National Science Foundation

Eascra Biotech specializes in developing DNA-inspired, nanoparticle-based delivery systems for targeted therapeutic treatment. Their platform, based on Janus base nanomaterials, encapsulates and stabilizes various therapeutic agents like mRNA, siRNA, proteins, and gene-editing tools, enabling precise delivery to hard-to-reach tissues such as cartilage, kidneys, and solid tumors. This approach enhances therapeutic efficacy, reduces systemic exposure, and preserves bioactivity, offering a low-cost, scalable alternative to existing treatments for chronic conditions.

Auxilium Health is creating low-cost, smart biomaterials for difficult-to-heal wounds.

Novaurum Biosciences develops AuPEC, a proprietary cell-based encapsulation technology for implanted orthopedic devices. This innovative approach combines microbiology and nanotechnology to create nano-biological coatings that significantly reduce infection rates and promote healing.

Students looking to work in state-of-the-art computer science and engineering facilities should look no further than the University of Nebraska at Omaha. UNO is a leader Bioinformatics, Computer Science and Management Information Systems programs. But UNO is not merely a four-year state university focused on science. With approximately 200 academic programs, this school offers an intimate atmosphere in a thriving city with numerous employment options for future graduates. The University of Nebraska at Omaha implements the Four-Year Guarantee resolution, meaning that the university will design a curriculum dedicated to permitting students to graduate as quickly as possible. UNO has a non-refundable $45 application fee for all applicants. The admissions requirements are based on core course prerequisites and performance requirements. The performance requirements for UNO admissions are a rank in the upper half of your graduating high school class and an ACT score of 20 or higher. The core course requirements are similar to the core requirements of other four-year colleges. UNO offers several types of financial aid to ease the cost of tuition. Not only do they have federal and state programs, but the school also offers scholarships, work-study programs and loans.

Rubi Laboratories is a California-based company that specializes in the development of technology to manufacture carbon-negative textiles. The firm utilizes innovative sustainable solutions to convert carbon emissions into natural fibers, resulting in biodegradable textiles. Its technology directly synthesizes threads, providing a natural resource for the production of viscose that is carbon-negative, as well as being water-chemical, land-neutral, traceable, and environmentally friendly. Rubi Laboratories aims to address the environmental impact of textile manufacturing by offering a more sustainable alternative in the industry.

Amphix Bio specializes in the development of therapeutic materials aimed at advancing regenerative medicine. The company focuses on creating nanofiber materials that replicate the structure and dynamic properties of human tissues. By integrating biological signals into these materials, Amphix Bio effectively guides cells to initiate regenerative processes. This innovative approach enables the development of therapies for repairing various tissues, including bone, cartilage, muscle, cardiovascular tissues, and nervous system components such as the brain and spinal cord. With expertise in materials science, stem cell biology, biomolecular design, engineering, medical physics, and informatics, Amphix Bio seeks to translate its promising preclinical and clinical trial results into viable treatment options.

Eradivir is a biotechnology company based in West Lafayette, Indiana. Founded in 2020, it focuses on developing a non-immunological targeting agent to combat the virus causing COVID-19.

The Wake Forest Institute for Regenerative Medicine (WFIRM) is a leader in translating scientific discovery into clinical therapies. Physicians and scientists at WFIRM were the first in the world to engineer laboratory-grown organs that were successfully implanted into humans. Today, this interdisciplinary team is working to engineer more than 30 different replacement tissues and organs and to develop healing cell therapies-all with the goal to cure, rather than merely treat, disease.

SMART Reproduction is a USDA-inspected and approved small ruminant semen and embryo collection facility.

Nanopath is a molecular diagnostics company that develops innovative platforms for rapid disease diagnosis. Its technology enables point-of-care testing, eliminating the need for nucleic acid amplification and supporting multiplexed detection. This allows patients and healthcare providers to access accurate diagnostic results within standard office visits, improving healthcare outcomes.

The Wistar Institute is a leading independent biomedical research institution dedicated to advancing medical knowledge through innovative research and training. Established as the first of its kind in the United States, it has grown from an anatomical teaching museum into a prominent center for basic biomedical research. Designated as a National Cancer Institute Cancer Center in 1972, The Wistar Institute focuses on critical areas such as cancer, immunology, and infectious diseases. Its groundbreaking discoveries have contributed to the development of vaccines for diseases like rabies, rubella, and rotavirus, as well as the identification of genes related to breast, lung, and prostate cancer. The Institute promotes a collaborative research environment aimed at addressing some of the most pressing challenges in the biomedical field.

Amplified Sciences is a molecular diagnostics company developing a point-of-care platform that enables early detection of debilitating diseases. Its sensor-based and optical reporter systems, combined with machine learning and multi-analyte assays, target cancers and chronic conditions such as pancreatic cancer and kidney disease. The technology supports detection of low-abundance disease markers in urine and saliva, with scalability to cost-effective point-of-care formats. The company leverages ultra-sensitive sensing and composition-of-matter intellectual property licensed from Purdue University to deliver single-molecule level detection. Its portfolio aims to improve patient outcomes by enabling rapid, minimally invasive testing, reducing unnecessary procedures, and expediting diagnosis across oncology and other disease areas. The platform has demonstrated prototype data and is positioned for broad applicability across multiple disease states.

MelliCell is a biotechnology company focused on addressing chronic diseases through innovative tissue engineering technology that targets fat cells. The company’s platform enables the conversion of human stem cells into mature fat cells, facilitating their accelerated growth to sizes that surpass conventional limits. This technology aims to shrink fat cells and improve metabolic health, making it applicable for treating conditions such as obesity, diabetes, aging, oncology, and inflammation. MelliCell’s experienced team is developing oral small molecules that not only decrease fat mass but also reverse disease hallmarks while preserving lean mass. The efficacy of MelliCell’s technology has been recognized through various awards and partnerships with leading biopharmaceutical firms, highlighting its potential to enhance health outcomes and quality of life for individuals worldwide.

Theromics Inc., founded in 2016, develops innovative cell therapies. It specializes in HeatSYNC Gel, a biopolymer thermal accelerant that enhances microwave and radiofrequency energy absorption during soft tissue ablation procedures. This gel amplifies heat movement, optimizes ablation zone shape, increases treatment area, and protects critical tissues.

The Wake Forest Institute for Regenerative Medicine (WFIRM) is a leader in translating scientific discovery into clinical therapies. Physicians and scientists at WFIRM were the first in the world to engineer laboratory-grown organs that were successfully implanted into humans. Today, this interdisciplinary team is working to engineer more than 30 different replacement tissues and organs and to develop healing cell therapies-all with the goal to cure, rather than merely treat, disease.

Astria Biosciences, based in Pittsburgh, specializes in developing innovative diagnostic and therapeutic solutions for cerebrovascular diseases. The company focuses on addressing neurosurgical challenges through molecular biology, advanced analytics, and small-molecule inhibitors, aiming to provide non-surgical alternatives for neurovascular conditions where surgery is currently the primary option.

New Jersey Institute of Technology (NJIT) is a research-focused university offering over 70 undergraduate and 15 graduate programs in technology, engineering, biological sciences, computer sciences, and related fields. NJIT is renowned for its state-of-the-art campus, highly qualified faculty, and pioneering research collaborations with local industries. The university's competitive admission process ensures high academic standards, with many students receiving financial aid.

Avisi Technologies Inc. is a Philadelphia-based company founded in 2017 that specializes in developing innovative solutions for glaucoma treatment. Its primary product, VisiPlate, is a next-generation, nanotechnology-enabled aqueous shunt designed to prevent blindness caused by glaucoma. Through its advanced technology, Avisi Technologies aims to enhance the effectiveness of glaucoma management and improve patient outcomes.

CerFlux develops advanced cancer modeling technology to enhance understanding and treatment of cancer. Its platform uses innovative ex vivo models to evaluate therapeutic efficacy on patient tumor tissue, enabling oncology professionals to improve patient outcomes through tailored therapy approaches.

Remedium Bio is a Boston-based gene therapy company dedicated to developing curative treatments for a variety of debilitating conditions. The company employs a unique approach that combines established technologies in innovative ways to address well-defined disease mechanisms. By modularly applying these proven technologies, Remedium Bio focuses on creating localized and targeted therapies centered on clinically validated molecules and pathways. Its pipeline includes leading gene therapy candidates in multiple fields, such as rheumatology, endocrinology, and neurology, aimed at providing effective treatments for a range of immune, age-related, and metabolic disorders.

Harpe Bioherbicide Solutions is a Raleigh-based company that provides sustainable weed-management solutions for organic and industrial agriculture. Harpe Bio's technologies deliver natural crop protection by utilizing a variety of plant extracts. The plant extracts serve as a platform that may be tailored to various weed management circumstances. Harpe's herbicide platform can be used alone or in conjunction with any currently marketed herbicide. Harpe's new modes and areas of action will improve synthetic herbicide efficacy, including the reduction of resistant weed populations.

Pheronym, Inc. is an agricultural biotechnology company based in Gainesville, Florida, that develops and manufactures environmentally friendly solutions for pest control. Founded in 2011 and formerly known as Kaplan Schiller Research, LLC, the company specializes in using pheromone-based technology to enhance the effectiveness of nematodes, microscopic roundworms that serve as organic insecticides. By leveraging pheromone spray, Pheronym is able to double the efficacy of nematodes, providing a sustainable alternative to traditional chemical pesticides while minimizing negative health and environmental impacts. In addition, the company offers an EPN-activator that utilizes nematodes’ own pheromones to influence their behavior and development, thereby enhancing pest management strategies for farmers and cultivators.

Founded in 2017, Nexilico is an early-stage biotechnology company based in Albany, California. It specializes in advancing microbiome and precision medicine research through the development of predictive computational platforms. These platforms aim to enhance drug design, development, and clinical outcomes for various therapeutics.

GENASSIST is a genetics company that provides assisted reproductive technology genetic consultation and testing services.

Oregon State University, founded in 1868, serves as the state’s Land Grant university and is distinguished by its Sea Grant, Space Grant, and Sun Grant designations, making it one of only two U.S. universities to hold this combination. It is recognized for its research excellence and community engagement, holding the Carnegie Foundation's top designation for research institutions. With a diverse student body of over 26,000 from across Oregon and more than 100 countries, Oregon State offers over 200 undergraduate and 80 graduate degree programs, including more than 30 online degrees through Oregon State Ecampus. The university operates 12 colleges, 15 Agricultural Experiment Stations, and 35 county Extension offices, as well as facilities such as the Hatfield Marine Sciences Center and OSU-Cascades. Oregon State's economic impact extends across all 36 counties in Oregon, contributing $2.06 billion to the state's economy. The university is noted for its strong programs in fields including conservation biology, agricultural sciences, nuclear engineering, and pharmacy, attracting high-achieving students committed to making a positive difference in society.

Oregon State University, founded in 1868, serves as the state’s Land Grant university and is distinguished by its Sea Grant, Space Grant, and Sun Grant designations, making it one of only two U.S. universities to hold this combination. It is recognized for its research excellence and community engagement, holding the Carnegie Foundation's top designation for research institutions. With a diverse student body of over 26,000 from across Oregon and more than 100 countries, Oregon State offers over 200 undergraduate and 80 graduate degree programs, including more than 30 online degrees through Oregon State Ecampus. The university operates 12 colleges, 15 Agricultural Experiment Stations, and 35 county Extension offices, as well as facilities such as the Hatfield Marine Sciences Center and OSU-Cascades. Oregon State's economic impact extends across all 36 counties in Oregon, contributing $2.06 billion to the state's economy. The university is noted for its strong programs in fields including conservation biology, agricultural sciences, nuclear engineering, and pharmacy, attracting high-achieving students committed to making a positive difference in society.

OmniVis is a biotechnology company specializing in pathogen detection. It offers an integrated portable platform that rapidly and accurately identifies pathogens in various environments, reducing the need for labor-intensive lab testing.

Atom Bioworks develops a DNA-antibody mimic platform for early detection and treatment of infectious diseases. Its technology combines computational biology, quantum chemistry, software, and machine learning to create pattern-recognition constructs.

Protabit develops protein engineering technology, combining computational modeling with high-throughput screening and directed evolution. This enables the exploration of diverse protein sequences for novel proteins, serving industrial, agricultural, and healthcare sectors.

Bespoke Biotherapeutics provides an effective natural immune response and overcomes the limitations of currently approved immunotherapies against cancer by inventing novel, customised living drugs called engineered B-cell therapeutics. They offer customised B-cell sourcing, isolation, activation, culture expansion, and non-viral genetic engineering methodologies uniquely suited to optimise commercial B-cell products for infusion.

BioSuperior Technology is a preclinical biotherapeutics company specializing in lung disease treatments. It has developed a novel, synthetic pulmonary surfactant prototype called BioSurf, which mimics the body's natural surfactant to facilitate breathing and deliver therapeutic drugs. This non-invasive, cost-effective technology aims to restore normal lung function and repair damaged lung tissue. Additionally, BioSuperior's platform has potential applications in treating other microvasculature-related illnesses, such as hemorrhagic stroke and chronic kidney disease.

Tiny Cargo specializes in the isolation and application of exosomes derived from bovine milk. Their technology enables industrial-scale production of these exosomes for various purposes, including pharmaceutical drug delivery, skin repair treatments, and nutritional applications.

Founded in Baltimore, Maryland in 2018, OncoSTING develops innovative therapies for bladder cancer. The company combines the potency of standard BCG immunotherapy with long-lived delivery of potent STING agonists to enhance immune response and improve safety profiles.

Brio provides strategic resourcing solutions to the biopharma, pharmaceutical, CRO, and medical device industries. They are skilled search experts with a passion for the science and art of recruiting, introducing only the best talent to preeminent companies.

NovoClade employs synthetic biology to develop environmentally friendly insect control solutions. It specializes in mosquito population management using gene-editing technology, creating sterile mosquitoes to reduce disease transmission without harming the environment.

Oculogenex is a biopharmaceutical company founded in 2020 and based in La Habra, California. It specializes in the development of gene therapies aimed at treating retinal disorders. The company’s innovative approach involves ocular regenerative gene therapy that protects retinal pigment epithelial cells from oxidative stress-induced cell death, a condition linked to macular degeneration. By focusing on these therapies, Oculogenex seeks to enable researchers to enhance the detection and treatment of retinal-related disorders, contributing significantly to advancements in this critical area of medical research.

Qualia Oto is a biomedical device company based in Dallas, Texas, founded in 2017. The company specializes in advanced cochlear implant technology, utilizing innovative shape-changing polymers and matrix-addressed electrode arrays to create high-quality devices tailored to individual medical and personal needs. Qualia Oto's technology aims to enhance auditory nerve stimulation through higher channel count cochlear implants and auditory brainstem implants, with future plans to incorporate machine learning-based stimulation for more precise outcomes.

Oxalo Therapeutics develops therapies to treat rare kidney diseases and prevent recurrent oxalate-related stones, focusing on primary hyperoxaluria and other oxalate pathologies. It leverages microbiome science, translational research, and early-stage technology to create a gut-derived therapy that safely removes oxalate from the body, reducing stone recurrence and related renal complications.

Aqua Science offers a global platform of technologies and fast and reliable solutions for the testing and treatment of water. They provide research and development, custom reagent and kit manufacture, product assembly, lyophilization services, and contract manufacturing services.

Uniphage is a biotechnology company specializing in the development of safer and more efficient alternatives to traditional pesticides in plant agriculture. It leverages artificial intelligence and bacteriophages (viruses that infect bacteria) to predict and combat specific bacterial infections. The company's primary focus is on citrus greening, a devastating disease costing the U.S. over $2 billion annually. By employing AI algorithms, Uniphage accelerates the discovery of effective and safe bacterial viruses, aiming to reduce the use of harmful fungicides, bactericides, and antibiotics, thereby minimizing risks to human health and the environment.

Simmbion develops a revolutionary system that manufactures therapies within the human body, acting as a 'living pharmacy'. This innovative approach aims to overcome challenges associated with traditional drug delivery methods such as complex manufacturing processes, repeated injections, and high costs. By creating adaptable, reversible cell therapies resistant to supply chain disruptions, Simmbion strives to provide affordable and equitable healthcare solutions globally.

EzraBio is a biotechnology company focused on enhancing ribosome profiling for researchers across various biological samples. The company specializes in RNA adenylation technology, which facilitates efficient and rapid cDNA library construction. By offering streamlined services that encompass sample preparation and deep sequencing, EzraBio aims to simplify the ribosome profiling process. This innovative approach allows medical professionals to uncover hidden coding potential, analyze translational responses, identify tumor-associated antigens, and advance mRNA therapeutics. Through its cutting-edge solutions, EzraBio supports researchers in their quest to deepen understanding of complex biological mechanisms.

Birch Biosciences develops a proprietary platform that uses artificial intelligence, bioinformatics, and high-throughput screening techniques to engineer enzymes. These enzymes efficiently break down plastic in a recycling process, producing virgin-quality, sustainable, and cost-competitive recycled outputs. This enables a circular plastics economy.

Creative BioTherapeutics is a biotechnology company dedicated to developing innovative therapies targeting the root causes of cancer affecting immune evasion and drug resistance. Its focus is on recurrent and drug-resistant cancers, aiming to provide effective treatments for adult and childhood cancers.

ViQi is a software-as-a-service company specializing in scientific image analysis. It offers a customizable platform that enables users to tailor services for data storage and analysis to meet their specific requirements. The company provides tools for image processing and informatics across various sectors, including life sciences, construction, and agriculture. ViQi's platform features a bio-image semantic query system, which facilitates module development and assists with intranet deployment. Additionally, it supports the hosting of image collections, allowing clients to view, investigate, share, and store complex data and images efficiently. This comprehensive approach enables swift results and enhances the discovery process for users in diverse fields.

Canomiks offers a genomics, bioinformatics, and AI-driven platform that empowers companies in functional food, dietary supplements, and skincare sectors to create safe and effective products. Its long-term goal is to make 'food as medicine' a reality.

Cryptyx Bioscience is a biopharmaceutical company focused on discovering new therapeutic natural products from bacteria without the use of genetics or cloning. Their innovative platform aims to activate silent biosynthetic gene clusters within bacteria, allowing them to unlock the full potential of culturable microbes. By employing a bioactivity-first approach, Cryptyx seeks to rapidly identify new antibiotics and antiviral drugs, addressing critical needs in combating infectious diseases prioritized by health organizations. The company's technology is designed to provide a broad range of medical services and therapeutic applications, ultimately enhancing treatment options for patients.

Iaso Therapeutics is a therapeutics company established in 2018 and located in East Lansing, Michigan. The company specializes in the development of vaccines aimed at improving human health and addressing infectious diseases. Its platform is designed to create vaccines targeting various deadly infections, including smallpox, yellow fever, and tetanus. By focusing on innovative vaccine technologies, Iaso Therapeutics seeks to equip healthcare professionals with effective tools to combat diseases and enhance overall public health.

PETL Fluidics is an operator of a microfluidics platform focused on laboratory research. The company specializes in controlling, managing, and experimenting within microfluidic environments. Its platform enables laboratories to conduct various applications, including chemical reactions, cell and organoid culture, advanced imaging, and mechanobiology. By providing custom-designed microfluidics, PETL Fluidics supports researchers in achieving precise control over experimental conditions, thus enhancing the capabilities of scientific inquiry and innovation.

NanoResearch is a technology company specializing in the research, design, development, and commercialization of advanced materials and energy storage solutions. The company focuses on creating innovative products, including energy storage devices, mechanical smart lighting systems, and nanobiomedical applications. By leveraging its nanotechnology expertise, NanoResearch aims to provide effective solutions to governments, businesses, and non-profit organizations, helping them to quickly enter the market with cutting-edge technologies. The company is committed to driving advancements in energy storage and smart materials, positioning itself as a key player in the development of breakthrough technologies that address contemporary challenges in these fields.

Ummino offers precision fermentation technology for fortified food and beverage products. The company's technology unlocks rare compounds to transform commodity ingredients into high-value functional foods.

Lura Health develops a non-invasive continuous health monitoring platform that uses saliva as a diagnostic fluid. The company integrates micro-sensors into orthodontic devices such as retainers, aligners, and brackets to continuously measure saliva analytes and securely transmit data to a smartphone app, enabling users to monitor oral health metrics and potentially support broader chronic disease management. Target markets include heart disease, chronic kidney disease, diabetes, and tooth decay. Founded in 2017, the company is based in Cambridge, Massachusetts.

Amphix Bio specializes in the development of therapeutic materials aimed at advancing regenerative medicine. The company focuses on creating nanofiber materials that replicate the structure and dynamic properties of human tissues. By integrating biological signals into these materials, Amphix Bio effectively guides cells to initiate regenerative processes. This innovative approach enables the development of therapies for repairing various tissues, including bone, cartilage, muscle, cardiovascular tissues, and nervous system components such as the brain and spinal cord. With expertise in materials science, stem cell biology, biomolecular design, engineering, medical physics, and informatics, Amphix Bio seeks to translate its promising preclinical and clinical trial results into viable treatment options.

Renerva is a rapidly-growing medical device company focused on developing and commercializing implantable technologies to enhance the outcomes of peripheral nerve repair procedures. The company specializes in creating surgical devices designed to facilitate nerve recovery and improve functionality post-injury, aiming to accelerate healing and restore patient mobility.

Hardshell Labs focuses on developing innovative, internet-controlled devices aimed at environmental conservation and wildlife protection. The company creates a network of remotely operable, artificial intelligence-enhanced rovers designed to deter bird pests from agricultural crops and various facilities, thereby minimizing avian damage. These devices are particularly valuable in protecting crops from ravens and crows, as well as in mitigating infestations at landfills and composting sites. Hardshell Labs also conducts predation research on endangered juvenile desert tortoises, assessing threats posed by avian predators, and engages in laser research for agricultural applications. Through these initiatives, the company provides humane and commercially viable solutions to wildlife management challenges, supporting both environmental conservation and agricultural productivity.

Cytocybernetics specializes in cellular electrophysiology. They offer a user-friendly plug-and-play dynamic clamp system called Cybercyte and provide comprehensive contract research organization (CRO) services, including FDA-mandated drug safety screening, custom electrophysiology studies, modeling, and analysis.

PureBiomass specializes in sustainable algae cultivation systems, offering innovative solutions that include waste water remediation, live feeds for shellfish, and omega-3 production. The company has developed a photo-bioreactor system designed to optimize algae growth, featuring a metal support cage, a plastic bladder for culture volume, and a sterile harvest apparatus for efficient collection of pre-concentrated culture. This system incorporates pH and temperature control options, allowing production facilities to minimize water consumption and reduce their carbon footprint. Through these services, PureBiomass aims to support sustainable fish production while contributing to environmental conservation efforts.

Visicell Medical develops innovative stem cell tracking tools designed to enhance the safety and efficacy of regenerative therapies. Their biodegradable tools enable real-time tracking of injected stem cells in both clinical and pre-clinical settings, aiming to improve treatment outcomes for patients with incurable diseases.

UCHU Biosensors develops a platform of tooth mounted sensors to effortlessly track health through saliva.

Stochastic Research Technologies is a software company specializing in providing research and innovative solutions for challenges within the chemical, pharmaceutical, and biomedical sectors. The company focuses on developing algorithms, methods, and tools that address complex issues related to energy and the environment, sustainability, molecular modeling, process management, and supply chain management. By leveraging advanced modeling and optimization techniques, Stochastic Research Technologies enables clients across various industries to effectively tackle biomedical problems and enhance their operational efficiencies. The company's commitment to applied research supports its mission to deliver practical and impactful solutions tailored to the needs of its diverse clientele.

Acrigen Biosciences is focused on advancing gene editing technologies to enhance the safety and efficiency of CRISPR-Cas based systems. Founded in 2019 and headquartered in Berkeley, California, the company develops precision gene editing solutions aimed at producing effective and safe in vivo drug therapies for various diseases. Acrigen's innovations include Acro proteins that regulate the CRISPR-Cas gene editing process, along with a bioinformatics discovery software platform designed to identify suitable CRISPR systems for human therapeutic applications. By improving anti-CRISPR proteins and optimizing genetic therapies, Acrigen aims to contribute significantly to the field of medicine and the treatment of debilitating conditions.

GeniPhys develops and commercializes standardized tunable collagen polymers and collagen-fibril materials for research and medical applications. It manufactures research-grade collymers and polymerization reagents that enable customization of 3D collagen-fibril matrices for in-vitro tissue systems used in drug discovery, toxicity testing, and basic cell and tissue research, as well as engineered tissue and organ constructs and 3D bioprinting. The product line includes oligomer polymerization kits, polymerization buffers, supplements, and related reagents, which are sold online. Founded in 2014 and based in Zionsville, Indiana, the company focuses on designing collagen materials for site-appropriate tissue generation and potential delivery of pharmaceutical and cell-based therapies.

Bactana Corporation develops a nutritional product platform aimed at enhancing microbiome health in livestock and other animals. Its core product, FPS-4, manipulates immunometabolism to boost productivity while promoting good health. Bactana serves cattle farmers primarily in Connecticut and New York, with headquarters in Farmington, Connecticut.

InvVax develops innovative vaccines using its proprietary platform. Its flagship product is a universal influenza vaccine designed to provide broad, long-lasting protection against all flu strains.

Isolere Bio, established in 2018, is a healthcare company specializing in biotherapeutic purification. Its core business involves simplifying and optimizing the manufacturing process of monoclonal antibodies and Adeno-Associated Viruses (AAVs) using Tangential Flow Filtration (TFF) technology. This streamlined approach aims to enhance global access to these vital drugs and research tools, while facilitating a seamless transition from laboratory-scale production to industrial-level output.

OmicsCraft offers customers access to a customised data analytics pipeline and a sample-to-solution service. They offer cloud-based platforms that allow them to build analytics pipelines for omic data preprocessing, mass spectrometric-based metabolite identification, differential analysis of metabolite profiles, and multi-omics integration.

Auctus Biologics is a pre-clinical biotechnology company that develops antibody mimetic scaffolds for therapeutic and diagnostic applications. The company is engineering a ribose-binding protein to bind clinical targets with an affinity comparable to monoclonal antibodies while offering enhanced stability that allows survival in extreme environments, including repeated boiling cycles. This approach aims to address antibodies' liabilities, such as instability and costly cold-chain requirements, in order to enable advanced treatments and reduce overall treatment costs.

Pathotrak specializes in rapid food safety testing. Its patented technology reduces detection time of pathogens like Salmonella and E. coli from days to hours, meeting FDA and USDA regulations. This innovation helps minimize holding costs, enables swift recalls, and enhances overall food safety.

Oncurie is a biotechnology company focused on developing targeted radionuclide therapy aimed at treating metastatic cancer. Utilizing innovative molecular radionuclide technology, Oncurie seeks to deliver radionuclides selectively to metastatic tissues, thereby enhancing treatment efficacy and improving patient outcomes. The company's goal is to provide healthcare providers with advanced therapeutic options that may lead to a cure for various forms of metastatic cancer, including breast cancer. Through its research and development efforts, Oncurie is committed to transforming cancer treatment and addressing unmet medical needs in oncology.

Psyonic, Inc. is a company that develops advanced bionic limbs aimed at enhancing the lives of individuals with amputations. Founded in 2015 and headquartered in Champaign, Illinois, Psyonic focuses on creating innovative prosthetic solutions, with its flagship product being an advanced bionic hand. This hand features muscle pattern recognition technology and provides sensory feedback, allowing users to perform everyday tasks with greater ease. Designed to be user-friendly and durable, it is also positioned to be affordable, with aspirations for full insurance coverage to eliminate out-of-pocket costs for users. The company's commitment to accessibility ensures that its products cater to a wide range of needs for those with amputations and injured limbs.

DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing innovative gene therapy treatments for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes advanced oral lipid nanoparticle technology to deliver mRNA and plasmid DNA directly to intestinal stem cells. This approach aims to address the root causes of gastrointestinal diseases, including Familial Adenomatous Polyposis (FAP), a hereditary condition that can lead to colorectal cancer and often necessitates invasive surgical interventions. DNALite's therapies seek to transform protein biologics into oral drugs, allowing for more effective and less invasive treatment options.

PZA Innovation is a biotechnology company focused on improving tuberculosis treatment through the development of a reliable pyrazinamide susceptibility testing method. By employing reverse engineering techniques, the company identifies the specific conditions under which pyrazinamide demonstrates effectiveness in vitro, targeting the living environment of mycobacterium tuberculosis within the host. This innovative approach aims to enable healthcare professionals to deliver next-generation pyrazinamide therapies, ultimately shortening the duration of tuberculosis treatment and enhancing patient outcomes.

BiRed Imaging specializes in advanced medical imaging technology focused on the early detection of breast cancer. The company has developed an innovative platform that combines infrared imaging with a proprietary computerized detection algorithm, enabling accurate identification of the size and location of tumors, particularly in patients with dense breast tissue. This technology serves as an effective adjunct to traditional breast cancer screening methods, helping clinicians to recognize high-risk patients at an early stage. By enhancing the accuracy and cost-effectiveness of breast cancer detection, BiRed Imaging aims to improve patient outcomes in oncology.

Lepidext is a company based in Lexington, Kentucky, founded in 2015 by Angelika Fath-Goodin and Bruce Webb. It specializes in pest control technology aimed at managing Lepidoptera populations, particularly targeting pests like the corn earworm. The company develops bio-pesticides that are species-specific, safe, and effective, providing an alternative to genetically modified plants and chemical pesticides. By leveraging a deep understanding of insect biology and collaborating closely with farmers, Lepidext seeks to enhance crop security and promote agricultural prosperity. Its innovative approach allows for improved pest management strategies, benefiting farmers and contributing to sustainable agricultural practices.

Nanopath is a molecular diagnostics company that develops innovative platforms for rapid disease diagnosis. Its technology enables point-of-care testing, eliminating the need for nucleic acid amplification and supporting multiplexed detection. This allows patients and healthcare providers to access accurate diagnostic results within standard office visits, improving healthcare outcomes.

MBF Therapeutics, Inc. is a veterinary oncology company based in Ambler, Pennsylvania, focused on developing and commercializing innovative therapies for cancer treatment in dogs and cats. The company specializes in targeted immunotherapies and small molecule drugs that effectively disrupt tumor cell metabolism while preserving healthy cells and organs. Its product portfolio includes MBFT-101, a combination therapy for sarcomas and lymphoma, featuring a proprietary polyamine transport inhibitor and a potent inhibitor of ornithine decarboxylase, as well as MBFT-102, an immunotherapy based on the tumor suppressor/cytokine mda-7/IL24, which has shown promise in human cancers. Additionally, MBF Therapeutics employs a proprietary DNA vaccine platform and delivery system to develop immunotherapeutic vaccines aimed at enhancing protective immunity against infectious diseases in companion animals and livestock. The company maintains a strategic partnership with the Lankenau Institute for Medical Research to further advance its research and development initiatives.

Atom Limbs is focused on advancing the field of prosthetics with its innovative mind-controlled artificial arms, specifically designed for under-elbow amputees and individuals with quadriplegia. The company’s flagship product, the Atom Touch, allows users to regain mobility by interpreting brain signals through implanted electrodes, facilitating natural and intuitive movement of the prosthetic limb. This technology is rooted in research and development conducted at the Johns Hopkins University Applied Physics Laboratory and has received substantial funding from DARPA. Atom Limbs aims to enhance the quality of life for those with mobility challenges by providing advanced, customizable solutions for artificial limbs.

Aqueduct Fluidics develops benchtop automation solutions for physical and life sciences research. Founded in 2019 and headquartered in Philadelphia, Pennsylvania, the company provides a software platform that streamlines workflows, integrates hardware components, and accelerates the development of benchtop-scale applications. The platform enables automation scripting and offers an interface to control and visualize hardware status while handling system integration tasks such as communication protocols, timing, user interfaces, and data persistence. By combining software tools with hardware control, Aqueduct Fluidics helps researchers design, test, and deploy automated experimental workflows with greater reliability and efficiency.

Rubi Laboratories is a California-based company that specializes in the development of technology to manufacture carbon-negative textiles. The firm utilizes innovative sustainable solutions to convert carbon emissions into natural fibers, resulting in biodegradable textiles. Its technology directly synthesizes threads, providing a natural resource for the production of viscose that is carbon-negative, as well as being water-chemical, land-neutral, traceable, and environmentally friendly. Rubi Laboratories aims to address the environmental impact of textile manufacturing by offering a more sustainable alternative in the industry.

Astek Diagnostics is a healthcare company that develops precision diagnostic technology aimed at improving the diagnosis and treatment of bacterial infections. The company has created a platform that assists physicians in prescribing the correct antibiotics for patients suffering from bacterial sepsis within one hour. Utilizing a single-use cartridge, Astek Diagnostics' device identifies bacterial infections in urine by measuring the oxygen consumption of bacterial species, significantly reducing the turnaround time for results. This innovative approach not only facilitates timely treatment but also helps combat antibiotic resistance through effective susceptibility testing.

Vulcan Biologics, established in 2019 and based in Irvine, California, specializes in biotechnology solutions for modulating microbiomes. Its core platform employs bacteriophages, which selectively target and alter specific gut bacteria without affecting the human host, aiming to achieve stable and persistent changes in the microbiome. This approach is primarily focused on treating gluten-related disorders, including gluten sensitivity and celiac disease.

FrostDefense, founded in 2018 and based in Champaign, Illinois, specializes in developing innovative frost protection solutions. The company focuses on creating environmentally friendly biofertilizers and patented sprayable compounds designed to combat early spring frost, particularly in vineyards and specialty fruit crops. By offering these frost protection products, FrostDefense aims to help vineyard owners prevent frost damage, thereby enhancing crop yield and improving labor management and mechanized farming operations.

Akttyva Therapeutics develops targeted therapeutics to address cell barrier dysfunction across multiple indications.

InsectaPel is a company specializing in biobased insect repellent textiles. It develops and manufactures fabrics treated with its proprietary, long-lasting repellent technology, aiming to protect users from biting insects that may transmit diseases. The company focuses on creating cost-effective, sustainable solutions that meet regulatory compliance standards, thereby offering an eco-friendly alternative to conventional repellents.

Zymosense specializes in automated aqueous two-phase extraction technology for efficient, scalable sorting of chiral-pure single-walled carbon nanotubes. Its platform enables various industries to access rapid evaluation, discovery, and design of new enzymes.

Synvivia, Inc. is a biotechnology company founded in 2016 and based in Berkeley, California. The company specializes in developing synthetic biology products, particularly ON-OFF switches for genetically engineered organisms. These protein switches are regulated by small molecules, allowing for precise control of biological functions within the organisms. Synvivia's innovations enable the creation of engineered organisms that can be utilized in healthcare, specifically for diagnosing diseases and enhancing treatment options. Additionally, the company is focused on generating biosensors to identify and improve enzymatic activities, thereby facilitating more effective disease management.

Uncaged Innovations develops sustainable alternatives to animal skin products. They create bio-based leather using plant materials and proprietary processing techniques, serving industries such as luxury fashion and automotives.

Cision Vision is a biotechnology company focused on developing and supplying innovative imaging medical products specifically designed for the examination of lymph nodes. Its advanced imaging devices enable pathologists to visualize, scan, and record lymph nodes in real-time with high contrast, eliminating the need for injections or radiation. By providing pathologists with tools that enhance the accuracy and consistency of pathology grossing, Cision Vision aims to modernize the field and improve the quality of care delivered to patients.

Organic Robotics Corporation, founded in 2018 and based in Rochester, New York, specializes in the design and development of advanced sensors for real-time touch measurement. The company's flagship product, Light Lace, utilizes fiber-optic technology to create a flexible sensor capable of bending and twisting to conform to the human body. This innovative sensor not only captures motion but also measures pressure, offering unique advantages in sensibility, elasticity, and washability at a competitive cost. Organic Robotics focuses on enhancing performance monitoring, particularly for professional athletes, by providing real-time feedback on motion, muscle fatigue, and vital signs. Their technology is designed for comfort and minimizes distraction, enabling accurate analysis of chest movement to deliver actionable insights that help optimize athletic performance.

Spekciton Biosciences specializes in biophotonic measurement systems and services aimed at enhancing agricultural performance and sustainability. The company develops innovative technologies that enable the rapid and precise detection of plant stress and viability, providing farmers with essential insights for improving crop management. Additionally, Spekciton offers biosensors designed to quickly identify soil and water contamination, supporting environmental health and agricultural productivity. Through its advanced measurement solutions, the company contributes to a better understanding of bioprocesses, ultimately aiding in the cultivation of resilient and sustainable crops.

BioSapien is a biotechnology company developing innovative, biodegradable implantable devices that deliver pharmaceuticals directly to cancer sites. Its flagship product, MediChip, uses 3D printing technology to create a mesh capable of sustained drug release, reducing systemic side effects and improving patient care.

Huue is a company specializing in sustainable dyeing solutions for the fashion and textile industries, particularly focusing on the denim supply chain. It employs innovative biotechnology to produce bio-synthesized dyes through a fermentation process involving naturally occurring microorganisms. This method not only eliminates the need for toxic chemicals traditionally used in dye production but also utilizes renewable resources, making it an eco-friendly alternative. By offering greener options for color production, Huue aims to support the industry's transition towards more sustainable practices, ultimately contributing to a more environmentally responsible approach to fashion.

Aracari Biosciences develops a vascularized micro-organ platform designed to accelerate drug discovery. This platform enables real-time imaging of vessel morphology, allowing for more authentic pre-clinical testing and enhancing decision-making in drug development.

Envivo Bio develops a non-invasive device that collects microbiome samples from all regions of the human gastrointestinal tract. The company is based in San Carlos, California.

Felix Biotechnology, Inc. is a San Francisco-based company founded in 2019 that specializes in developing biotherapeutics to combat microbial challenges in human health. The company focuses on creating treatments for antibiotic-resistant strains of bacteria and fungi, aiming to address the urgent need for effective management of infectious diseases. By accelerating the deployment of novel biotherapeutics, Felix Biotechnology seeks to provide healthcare professionals with precise and effective tools to tackle these pressing health issues.

Soil Culture Solutions, LLC, founded in 2014 and based in Tampa, Florida, specializes in innovative genetic alteration technology. The company focuses on developing citrus trees using CRISPR editing techniques to enhance their resistance to severe diseases that threaten the citrus industry. Soil Culture Solutions holds exclusive licenses to patents from community universities, enabling it to employ precision breeding methods to effectively combat these critical infections in citrus crops.

AgroSpheres, LLC is a biotechnology company based in Charlottesville, Virginia, that specializes in innovative pesticide delivery technologies for the agriculture industry. Founded in 2016, AgroSpheres develops engineered bio-particles designed to deliver pesticide-degrading enzymes, which help to minimize waiting periods between pesticide application and harvest. The company employs a unique platform technology that enhances the performance of various crop protection products, including fungicides, insecticides, and herbicides. By utilizing bioengineering and industrial fermentation techniques, AgroSpheres creates biodegradable encapsulation solutions that aim to reduce harmful pesticide residues on plants, ultimately promoting healthier agricultural practices and improving the overall well-being of crops.

Fortiphyte offers agricultural protection products that help to protect crops from disease and reduce fungicide use. The company was founded in 2017 and is based in Berkeley, California.

Labby Inc. is a technology company based in Cambridge, Massachusetts, specializing in smartphone-based optical spectrometry for agricultural applications. Founded in 2017, Labby develops an artificial intelligence-driven platform that translates raw optical data into actionable insights, primarily for farmers and dairy processors. Its flagship product allows for rapid and precise testing of milk composition, facilitating early mastitis detection and enabling timely intervention. Additionally, Labby's technology is applicable across various sectors, including the detection of spoilage, adulterants, and contamination in the supply chain, as well as providing analytics for tracking harvest cycles and meteorological data mapping. The company also caters to the beer and wine industries, offering portable testing devices for quality control and counterfeit detection, serving a diverse clientele that ranges from large breweries to homebrewers.

Biochip Labs is a company based in Cleveland, Ohio, founded in 2019. It specializes in providing laboratory testing services focused on blood disorders, particularly sickle cell disease and thalassemia. The company offers a range of proprietary microfluidic biomarker assays, including tests for blood cell adhesion, red blood cell deformability, whole blood rheology, and endothelialized microfluidics. These assays are designed to evaluate the effectiveness of emerging targeted and curative therapies, allowing clinicians to monitor patients' responses to treatment accurately.