National Science Foundation

The National Science Foundation is an independent federal agency in the United States that funds and supports research and education in science and engineering. It funds fundamental research and education across all fields of science and engineering and administers non-dilutive funding programs to aid early‑stage technology development, helping translate discoveries into commercially viable products and services. Through grants and fellowships, the NSF supports researchers, educators, and startups, contributing to innovation and U.S. competitiveness. The agency operates with a substantial budget to advance science, engineering, and STEM education nationwide.

James Donlon

Program Director

Sean L. Jones

Assistant Director for Mathematical and Physical Sciences

Debasis Majumdar

Program Director

Graciela Narcho

Staff Associate

Sethuraman Panchanathan

Director

Past deals in Wisconsin

University of Wisconsin-Madison

Grant in 2023
The University of Wisconsin-Madison is a comprehensive land-grant university offering over 600 undergraduate and graduate majors across a wide range of disciplines.

WiSys Technology Foundation

Grant in 2023
WiSys Technology Foundation works hand in hand with the University of Wisconsin System to support research and technology development, link campus innovators with industry leaders and speed technology transfer through patent and licensing activities.

The Water Council

Grant in 2023
The Water Council, established in 2009, is a Milwaukee-based organization dedicated to positioning the region as a global leader in water technology. It achieves this by fostering collaboration among water technology companies, entrepreneurs, academic research programs, and related professionals. The Council's primary focus is on driving economic development, research, and education in the water sector.

Marquette University Endowment

Grant in 2023
Marquette University is a prominent Catholic institution located in Milwaukee, Wisconsin, offering a diverse array of undergraduate and graduate programs. The university provides degrees in fields such as Civil and Environmental Engineering, Operations and Supply Chain Management, and Clinical Mental Health Counseling, alongside professional training in law, medicine, and dentistry. Marquette emphasizes the integration of Christian values into its educational framework, promoting community service and volunteerism among its students. The campus features dedicated resources for community engagement and spiritual growth, including a community service center and a ministry center. Additionally, the university supports students through financial aid options to help alleviate the cost of tuition. Marquette University aims to foster a comprehensive educational experience rooted in Jesuit principles, preparing students to contribute positively to society.

University of Wisconsin Oshkosh

Grant in 2022
University of Wisconsin Oshkosh provides students with state-wide resources and ensures academic quality and accountability. UW Oshkosh is committed to providing students with a broad knowledge base and transferable skills as well as a strong sense of values and ethics that prepares them for civic leadership in society. UW Oshkosh is part of the robust University of Wisconsin System—one of the largest systems of public higher education in the country. It was founded in 1871 and its headquarters is located in Oshkosh, Wisconsin.

Rapid Radicals Technology

Grant in 2021
Rapid Radicals Technology develops wastewater treatment solutions for municipal sewer systems to address combined sewer overflows. Founded in 2016 and based in Milwaukee, Wisconsin, the company operates a catalytically enhanced ozone-based oxidation process designed to treat wastewater cost-effectively, improving system performance and resilience for municipalities, industrial users, and emergency responders.

Pyran

Grant in 2021
Founded in 2017, Pyran develops renewable industrial chemicals from agricultural and wood waste. Its proprietary process converts these resources into a five-carbon diol used in coatings, adhesives, plastics, and polyols production. The company serves chemical industries, offering cost-effective and environmentally sustainable alternatives to petroleum-derived products.

AgraFilms

Grant in 2021
AgraFilms is a biotechnology company focused on mitigating crop loss through sustainable, natural solutions. Founded in 2019 and based in Madison, Wisconsin, the company develops biocontrol approaches that utilize amoebic biocontrol to promote crop health and reduce the need for synthetic antibiotics and pesticides. Its technology aims to prevent the spread of agricultural diseases and to protect crops by offering an all-natural method to address environmental and health challenges associated with crop damage, delivering long-term solutions for farmers.

Pyran

Grant in 2020
Founded in 2017, Pyran develops renewable industrial chemicals from agricultural and wood waste. Its proprietary process converts these resources into a five-carbon diol used in coatings, adhesives, plastics, and polyols production. The company serves chemical industries, offering cost-effective and environmentally sustainable alternatives to petroleum-derived products.

VasoGnosis

Grant in 2020
Founded in 2019, VasoGnosis is a Milwaukee-based healthcare technology company specializing in AI-powered diagnostic and surgical planning software for cerebrovascular diseases like brain aneurysms. Its platform automates analysis of brain aneurysms, providing advanced visualization tools to aid neurosurgeons and interventional neuroradiologists in decision-making.

Cellulose Sciences International

Grant in 2020
Cellulose Sciences International develops novel methods for utilizing celluloses and lignocellulosic. The headquarters of the company are in Madison, Wisconsin.

Rapid Radicals Technology

Grant in 2019
Rapid Radicals Technology develops wastewater treatment solutions for municipal sewer systems to address combined sewer overflows. Founded in 2016 and based in Milwaukee, Wisconsin, the company operates a catalytically enhanced ozone-based oxidation process designed to treat wastewater cost-effectively, improving system performance and resilience for municipalities, industrial users, and emergency responders.

Pyran

Grant in 2019
Founded in 2017, Pyran develops renewable industrial chemicals from agricultural and wood waste. Its proprietary process converts these resources into a five-carbon diol used in coatings, adhesives, plastics, and polyols production. The company serves chemical industries, offering cost-effective and environmentally sustainable alternatives to petroleum-derived products.

Cell Reprogramming & Therapeutics

Grant in 2018
Cell Reprogramming & Therapeutics is a Wisconsin-based company founded in 2013 that specializes in developing innovative cell reprogramming technologies aimed at treating central nervous system diseases. By transforming patients' somatic cells into specific differentiated cell types, the company enables the generation of stem cell lines that can be utilized for disease modeling, toxicity screening, and drug discovery. This approach facilitates the creation of cellular models and therapeutics tailored for neurological disorders, providing researchers with valuable tools to advance their understanding and treatment of these complex conditions.

SHINE

Series B in 2018
SHINE develops and deploys fusion-based technology to produce medical isotopes and neutron sources. Its processes generate molybdenum-99, a precursor to technetium-99m used in diagnostic imaging, and lutetium-177 for diagnostic and therapeutic use, along with iodine-131 and iodine-125 for thyroid treatment and brachytherapy, and xenon-133 for lung and brain imaging. The company’s systems also provide neutron sources for industrial imaging, radiation-effects testing, and fusion materials research. In addition to medical isotopes, SHINE aims to recycle nuclear waste and advance fusion power as a source of clean energy. The business serves health care and industrial customers worldwide. SHINE is based in Janesville, Wisconsin, with an office in Alkmaar, Netherlands.

Carroll University Endowment

Grant in 2018
Carroll University Endowment is a non-profit organization based in Waukesha, Wisconsin, managing an investment fund to support various educational initiatives at Carroll University. The earnings from these investments primarily finance scholarships, professorships, research projects, and academic programs, enhancing students' learning experiences and opportunities. The endowment's assets are overseen by the university's board of trustees, ensuring responsible management and growth.

ConsortiEX

Grant in 2017
ConsortiEX is a health care technology company that provides information technology systems and services for pharmacies to manage the ordering, distribution, and tracking of pharmaceuticals for hospitals in the United States. Its flagship product, Assure-Trak, is an enterprise resource planning system designed to collect, integrate, manage, and share pharmacy information for sterile product compounding.

Xylome

Grant in 2016
Xylome offers solutions that enable first generation biofuel manufacturers to use second generation technology solutions in their manufacturing process. It offers them with advisory, implementation, and support services. Xylome develops a range of non-conventional yeasts and yeast technology solutions for experimental assessments. Xylome was founded by Thomas W Jeffries in 2007. It is based in Madison, Wisconsin.

GlucanBio

Grant in 2016
GlucanBio is a biotechnology company specializing in the conversion of biomass into valuable chemical products. Originating from research at the University of Wisconsin and Iowa State's Center for Biorenewable Chemicals, GlucanBio aims to produce furan derivatives such as furfural, HMF, DMF, THF, and FDCA more efficiently and cost-effectively than traditional methods. The company leverages its team's expertise in catalysis, intellectual property management, engineering scale-up, and early-stage commercialization, led by renowned catalytic chemist Jim Dumesic and industry veteran Brent Shanks. GlucanBio's innovative technology fractionates biomass under mild conditions to generate solvents directly from the feedstock, facilitating a sustainable approach for clients seeking eco-friendly alternatives.

Fiberstar

Grant in 2015
Founded in 1998, Fiberstar specializes in researching, developing, and manufacturing natural ingredients that enhance food quality and nutrition. Its flagship product, Citri-Fi, derived from orange pulp, offers multi-functional benefits such as moisture management, partial fat replacement, and label-friendly properties. The company's products serve a wide range of industries including bakery, dairy, and meat products.

ConsortiEX

Grant in 2015
ConsortiEX is a health care technology company that provides information technology systems and services for pharmacies to manage the ordering, distribution, and tracking of pharmaceuticals for hospitals in the United States. Its flagship product, Assure-Trak, is an enterprise resource planning system designed to collect, integrate, manage, and share pharmacy information for sterile product compounding.

C-Motive

Grant in 2015
C-Motive Technologies Inc. is a cleantech startup based in Madison, Wisconsin, founded in 2012, that specializes in the development and manufacturing of innovative electric motors. The company has created a unique electrostatic motor technology that operates using static electricity, eliminating the need for rare earth materials and significantly reducing copper usage. This advanced motor design delivers high torque density suitable for various applications, including industrial use and e-mobility, while also contributing to lower carbon emissions. C-Motive's motors utilize lightweight metals, plastics, and dielectric materials, offering twice the power at half the weight compared to traditional electric motors. With a focus on efficiency, their technology boasts over 90% efficiency in direct drive and low-speed applications, positioning C-Motive at the forefront of sustainable motor solutions.

SHINE

Grant in 2015
SHINE develops and deploys fusion-based technology to produce medical isotopes and neutron sources. Its processes generate molybdenum-99, a precursor to technetium-99m used in diagnostic imaging, and lutetium-177 for diagnostic and therapeutic use, along with iodine-131 and iodine-125 for thyroid treatment and brachytherapy, and xenon-133 for lung and brain imaging. The company’s systems also provide neutron sources for industrial imaging, radiation-effects testing, and fusion materials research. In addition to medical isotopes, SHINE aims to recycle nuclear waste and advance fusion power as a source of clean energy. The business serves health care and industrial customers worldwide. SHINE is based in Janesville, Wisconsin, with an office in Alkmaar, Netherlands.

Xylome

Grant in 2015
Xylome offers solutions that enable first generation biofuel manufacturers to use second generation technology solutions in their manufacturing process. It offers them with advisory, implementation, and support services. Xylome develops a range of non-conventional yeasts and yeast technology solutions for experimental assessments. Xylome was founded by Thomas W Jeffries in 2007. It is based in Madison, Wisconsin.

GlucanBio

Grant in 2015
GlucanBio is a biotechnology company specializing in the conversion of biomass into valuable chemical products. Originating from research at the University of Wisconsin and Iowa State's Center for Biorenewable Chemicals, GlucanBio aims to produce furan derivatives such as furfural, HMF, DMF, THF, and FDCA more efficiently and cost-effectively than traditional methods. The company leverages its team's expertise in catalysis, intellectual property management, engineering scale-up, and early-stage commercialization, led by renowned catalytic chemist Jim Dumesic and industry veteran Brent Shanks. GlucanBio's innovative technology fractionates biomass under mild conditions to generate solvents directly from the feedstock, facilitating a sustainable approach for clients seeking eco-friendly alternatives.

HealthMyne

Grant in 2015
HealthMyne, Inc. is a healthcare informatics company based in Madison, Wisconsin, specializing in innovative search, analytics, and imaging solutions tailored for cancer care providers. Founded in 2013, the company aims to enhance clinical decision-making by offering real-time, evidence-based imaging insights that support optimized patient care and reduce delivery costs. HealthMyne's technology enables physicians to manipulate tumor images and access electronic health records and image repositories, facilitating the diagnosis and treatment of similar cases. The company’s platform also focuses on improving patient management through features such as automatic tumor staging, dose overlays, and specialized reporting, which streamline clinical workflows and support precision medicine initiatives.

Imbed Biosciences

Grant in 2013
Imbed Biosciences is a medical device company that develops technologies for embedding bioactive molecules in wound dressings and surgical implants. Its platform includes antimicrobial wound dressings and biocompatible matrices that balance moisture and enable long-term, non-toxic antibacterial release to prevent infections and promote wound healing. The company seeks to improve outcomes in burns, ulcers, and soft-tissue injuries while reducing wound-management costs. It originated as a spin-off from the University of Wisconsin–Madison and is based in Madison, Wisconsin.

C-Motive

Grant in 2013
C-Motive Technologies Inc. is a cleantech startup based in Madison, Wisconsin, founded in 2012, that specializes in the development and manufacturing of innovative electric motors. The company has created a unique electrostatic motor technology that operates using static electricity, eliminating the need for rare earth materials and significantly reducing copper usage. This advanced motor design delivers high torque density suitable for various applications, including industrial use and e-mobility, while also contributing to lower carbon emissions. C-Motive's motors utilize lightweight metals, plastics, and dielectric materials, offering twice the power at half the weight compared to traditional electric motors. With a focus on efficiency, their technology boasts over 90% efficiency in direct drive and low-speed applications, positioning C-Motive at the forefront of sustainable motor solutions.

NanoAffix

Grant in 2013
NanoAffix Science LLC is a small business focused on developing advanced technologies for real-time detection of contaminants in drinking water. Utilizing patented graphene-based sensors, the company enables rapid and cost-effective onsite testing for harmful substances like lead and other heavy metal ions, bacteria, and nutrients in water. Founded as a spin-off from the University of Wisconsin-Milwaukee Research Foundation, NanoAffix aims to provide cleaner, smarter, and digital water solutions. The company has gained support from notable water manufacturing firms to prototype innovative sensor chips leveraging graphene transistor technology. Through its efforts, NanoAffix is committed to enhancing water safety and quality for consumers.

HealthMyne

Grant in 2013
HealthMyne, Inc. is a healthcare informatics company based in Madison, Wisconsin, specializing in innovative search, analytics, and imaging solutions tailored for cancer care providers. Founded in 2013, the company aims to enhance clinical decision-making by offering real-time, evidence-based imaging insights that support optimized patient care and reduce delivery costs. HealthMyne's technology enables physicians to manipulate tumor images and access electronic health records and image repositories, facilitating the diagnosis and treatment of similar cases. The company’s platform also focuses on improving patient management through features such as automatic tumor staging, dose overlays, and specialized reporting, which streamline clinical workflows and support precision medicine initiatives.

GlucanBio

Grant in 2013
GlucanBio is a biotechnology company specializing in the conversion of biomass into valuable chemical products. Originating from research at the University of Wisconsin and Iowa State's Center for Biorenewable Chemicals, GlucanBio aims to produce furan derivatives such as furfural, HMF, DMF, THF, and FDCA more efficiently and cost-effectively than traditional methods. The company leverages its team's expertise in catalysis, intellectual property management, engineering scale-up, and early-stage commercialization, led by renowned catalytic chemist Jim Dumesic and industry veteran Brent Shanks. GlucanBio's innovative technology fractionates biomass under mild conditions to generate solvents directly from the feedstock, facilitating a sustainable approach for clients seeking eco-friendly alternatives.
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