National Science Foundation

Pennsylvania State University, founded in 1855, is Pennsylvania’s largest public university and the state’s only land‑grant institution. It operates 24 campuses across the Commonwealth, offering a broad range of undergraduate, graduate, and professional programs. The university emphasizes teaching, research, and public service, collaborating with partners to apply knowledge to community needs. Its specialized schools include the College of Medicine, Dickinson School of Law, World Campus, and Pennsylvania College of Technology. Students from around the world enroll, and many transfer from other Penn State campuses to the flagship University Park campus. The university’s governance is overseen by a board of trustees, and its assets are managed to support students, faculty, staff, and the broader community.

Avisi Technologies Inc. is a Philadelphia-based company founded in 2017 that specializes in developing innovative solutions for glaucoma treatment. Its primary product, VisiPlate, is a next-generation, nanotechnology-enabled aqueous shunt designed to prevent blindness caused by glaucoma. Through its advanced technology, Avisi Technologies aims to enhance the effectiveness of glaucoma management and improve patient outcomes.

Pennsylvania State University, founded in 1855, is Pennsylvania’s largest public university and the state’s only land‑grant institution. It operates 24 campuses across the Commonwealth, offering a broad range of undergraduate, graduate, and professional programs. The university emphasizes teaching, research, and public service, collaborating with partners to apply knowledge to community needs. Its specialized schools include the College of Medicine, Dickinson School of Law, World Campus, and Pennsylvania College of Technology. Students from around the world enroll, and many transfer from other Penn State campuses to the flagship University Park campus. The university’s governance is overseen by a board of trustees, and its assets are managed to support students, faculty, staff, and the broader community.

Carnegie Mellon University is a renowned private research university, offering undergraduate and graduate programs across diverse fields, with a strong focus on technology and arts. It is particularly distinguished for its School of Computer Science, recognized globally for its research and education, and the Heinz College of Information Systems and Public Policy, which uniquely combines management and policy expertise. The university serves various sectors, including education, technology, and the arts, contributing significantly to these fields through its academic programs and research.

Elizabethtown College, founded in 1899, is a private non-profit liberal arts institution located in the United States, with an enrollment of fewer than 2,000 students and a student-to-faculty ratio of less than 13:1. The college offers over 50 majors and 80 minors leading to bachelor's degrees, along with a recently introduced master's degree program in Occupational Therapy. Emphasizing the development of writing, communication, creativity, and critical thinking skills, Elizabethtown provides a comprehensive admissions process that evaluates academic achievements, integrity, work ethic, and extracurricular involvement. More than 85% of students reside on campus, contributing to a vibrant student life enriched by various clubs, organizations, and service opportunities. Financial aid options, including need-based federal aid and institutional merit scholarships, are available for eligible students, and all applicants are considered for merit scholarships during the review process.

Strados Labs, LLC is a medical technology company based in Philadelphia, Pennsylvania, specializing in respiratory health management through innovative sensor-based solutions. Founded in 2016, the company has developed a wearable device that provides real-time insights into breathing patterns, sounds, and speed. This device is equipped with clinical-grade biosensors and smart software, allowing for continuous monitoring of respiratory conditions such as asthma and chronic obstructive pulmonary disease. By connecting to a mobile application, Strados enables users and healthcare providers to access and analyze respiratory data, facilitating informed health decisions and remote patient monitoring.

Founded in 2020, Phlux Technologies specializes in developing innovative 3D sensor technology for robotics and automation. Its products enhance safety and efficiency by enabling robots to navigate effectively, protecting workers from hazards, and detecting obstacles.

OsciFlex LLC, established in 2017 and headquartered in Philadelphia, Pennsylvania, specializes in developing a medical device aimed at preventing blood clots from forming at valves. The company's innovative product mimics nature's process to provide more effective compression therapy, reducing the risk of Venous thromboembolism (VTE) in patients and potentially decreasing reliance on costly and risky anti-coagulation pharmaceuticals.

MBF Therapeutics, Inc. is a veterinary oncology company based in Ambler, Pennsylvania, focused on developing and commercializing innovative therapies for cancer treatment in dogs and cats. The company specializes in targeted immunotherapies and small molecule drugs that effectively disrupt tumor cell metabolism while preserving healthy cells and organs. Its product portfolio includes MBFT-101, a combination therapy for sarcomas and lymphoma, featuring a proprietary polyamine transport inhibitor and a potent inhibitor of ornithine decarboxylase, as well as MBFT-102, an immunotherapy based on the tumor suppressor/cytokine mda-7/IL24, which has shown promise in human cancers. Additionally, MBF Therapeutics employs a proprietary DNA vaccine platform and delivery system to develop immunotherapeutic vaccines aimed at enhancing protective immunity against infectious diseases in companion animals and livestock. The company maintains a strategic partnership with the Lankenau Institute for Medical Research to further advance its research and development initiatives.

Aqueduct Fluidics develops benchtop automation solutions for physical and life sciences research. Founded in 2019 and headquartered in Philadelphia, Pennsylvania, the company provides a software platform that streamlines workflows, integrates hardware components, and accelerates the development of benchtop-scale applications. The platform enables automation scripting and offers an interface to control and visualize hardware status while handling system integration tasks such as communication protocols, timing, user interfaces, and data persistence. By combining software tools with hardware control, Aqueduct Fluidics helps researchers design, test, and deploy automated experimental workflows with greater reliability and efficiency.

Precision Neuroscopics is a medical device company headquartered in Pittsburgh, Pennsylvania, specializing in the development of advanced high-density electroencephalography (EEG) systems. The company focuses on creating innovative technologies that enable the non-invasive detection of brain signals, particularly those indicative of worsening traumatic brain injury. By engineering high-density and user-friendly brain recording systems, Precision Neuroscopics aims to enhance the quality of EEG signal recording while reducing clinical time and costs for healthcare providers.

Learnics is a digital learning platform established in 2017 and headquartered in East Stroudsburg, Pennsylvania. The company focuses on equipping educators with tools to gain insights into students' online learning behaviors, thereby enhancing the teaching and learning experience. Learnics' platform supports schools in their transition to digital education by revealing students' online experiences. It allows teachers to guide students during research assignments, emphasizing the significance of the learning process alongside the final outcomes. Through its tools, the platform enables the creation of classes and assignments where learners can log their online research activities, capturing targeted records of student engagement and performance in a digital environment.

SusMaX is a construction company based in Philadelphia, Pennsylvania, founded in 2020. It specializes in the production of lightweight aggregate for the construction industry, utilizing innovative thermodynamics-based technology to convert waste coal combustion products into structural lightweight concrete. This process enhances the workability and extends the service life of concrete, offering a sustainable solution to the industry's demand for efficient building materials.

Workers First is a research and design company founded in 2016 and headquartered in Pittsburgh, Pennsylvania. The company specializes in developing innovative polymer materials that enhance worker protection, particularly in hazardous environments. Its patented polymer technology is designed to neutralize acids on contact, making it suitable for use in personal protective equipment and acid-proof linings. This advancement enables workers to perform their jobs safely and effectively in situations where they are exposed to corrosive substances, thereby improving overall safety and productivity in the workplace.

NeuroTechR3 is a biomedical device and digital health start-up focused on developing affordable rehabilitation technologies aimed at enhancing upper extremity function in individuals affected by brain injuries, such as stroke and cerebral palsy. The company's flagship innovation, R3THATM, leverages machine learning-driven cloud technology and exergames tailored to promote neuroplasticity, incorporating motion tracking, analytics, and real-time biofeedback. Founded in 2020 by four women as a spinout from the New Jersey Institute of Technology and Rutgers School of Health Professions, NeuroTechR3 is committed to transforming the rehabilitation industry into a proactive, patient-centered process. The company operates from locations in Newark, NJ, and Philadelphia, PA, and has established partnerships with rehabilitation hospitals, outpatient centers, and therapists. With its expertise in biomedical engineering and computer science, the team is equipped to adapt swiftly to industry needs, aiming to provide sustainable and accessible rehabilitation solutions for individuals with various impairments. Through the advancement of rehabilitation devices and machine learning technology, NeuroTechR3 seeks to make a significant positive impact on global health outcomes.

Arcadia University is a private institution located in Glenside, Pennsylvania, offering over 45 undergraduate, graduate, and doctoral programs. Known for its distinctive fields such as Creative Writing, Religion, Engineering, Fashion Studies, and Veterinary Medicine, Arcadia also provides unique dual degree options like Physical Therapy and Public Health. Recognized for its international study options and career services, the university supports students through financial aid opportunities.

NeuroTechR3 is a biomedical device and digital health start-up focused on developing affordable rehabilitation technologies aimed at enhancing upper extremity function in individuals affected by brain injuries, such as stroke and cerebral palsy. The company's flagship innovation, R3THATM, leverages machine learning-driven cloud technology and exergames tailored to promote neuroplasticity, incorporating motion tracking, analytics, and real-time biofeedback. Founded in 2020 by four women as a spinout from the New Jersey Institute of Technology and Rutgers School of Health Professions, NeuroTechR3 is committed to transforming the rehabilitation industry into a proactive, patient-centered process. The company operates from locations in Newark, NJ, and Philadelphia, PA, and has established partnerships with rehabilitation hospitals, outpatient centers, and therapists. With its expertise in biomedical engineering and computer science, the team is equipped to adapt swiftly to industry needs, aiming to provide sustainable and accessible rehabilitation solutions for individuals with various impairments. Through the advancement of rehabilitation devices and machine learning technology, NeuroTechR3 seeks to make a significant positive impact on global health outcomes.

Arieca LLC, founded in 2018 and based in Pittsburgh, Pennsylvania, specializes in the development and distribution of Thubber, a thermally conductive rubber composite. This innovative material merges the compliance and elasticity of soft silicone rubber with the thermal conductivity of metal, making it suitable for various applications such as circuit wiring, sensors, and passive heat exchangers. Arieca's product addresses heat management challenges in the electronics industry, enhancing performance while ensuring safe interactions between devices and users. By providing an alternative to traditional rubber, Arieca aims to improve the efficiency of electronic components across multiple sectors.

FloBio is a Philadelphia-based company founded in 2017 that specializes in point-of-care diagnostics for assessing bleeding risk through real-time blood analysis. The company has developed an innovative fluidic-based diagnostic platform that leverages microfluidic technology to measure blood clotting function under physiologic conditions. This platform delivers rapid and actionable measurements, allowing clinicians to make informed decisions and personalize patient management during critical moments. By focusing on enhancing the accuracy and immediacy of blood analysis, FloBio aims to improve outcomes in medical situations where bleeding risk is a significant concern.

OYS Mobility is a Philadelphia-based company founded in 2020 that specializes in developing innovative prosthetic technology aimed at improving access to healthcare and assistive devices for individuals with limb loss or deformity. The company utilizes a computational approach to digitize biomechanical designs, enabling healthcare professionals to create custom prosthetic devices tailored to individual needs. Through its advancements in prosthetic technology, OYS Mobility seeks to enhance the quality of life for those affected by limb loss or deformity, ensuring that essential healthcare solutions are within reach for all.

Plexision develops cellular biomarkers and personalized diagnostic tests for immunological disorders and solid organ transplantation. Its Pleximmune blood test predicts transplant rejection by measuring antigen-specific white blood cells, supported by patent-pending technology. The company operates a CLIA-certified central laboratory in Pittsburgh providing testing services for transplant recipients and drug developers. Its platform enables assessment of disease risk, prediction of drug efficacy for individual patients, and guidance on dosing for novel immunological therapies, with capabilities including rapid six-hour panels for conditions such as CMV infection and transplant rejection, and a focus on pediatric liver and intestine transplant patients.

Avisi Technologies Inc. is a Philadelphia-based company founded in 2017 that specializes in developing innovative solutions for glaucoma treatment. Its primary product, VisiPlate, is a next-generation, nanotechnology-enabled aqueous shunt designed to prevent blindness caused by glaucoma. Through its advanced technology, Avisi Technologies aims to enhance the effectiveness of glaucoma management and improve patient outcomes.

Founded in 2017, Thermaquil is a medical device company based in Philadelphia, Pennsylvania. It specializes in developing non-invasive, drug-free solutions to manage severe pain and other conditions caused by overactive nerves.

Behaivior LLC is a digital health company based in Pittsburgh, Pennsylvania, focused on predicting and preventing addiction relapses through innovative technology. Founded in 2017, Behaivior integrates wearable devices with machine learning algorithms to analyze real-time data from various physiological metrics, such as heart rate and skin temperature. The company’s platform, known as Recovery, employs this data to deliver timely interventions tailored to the needs of individuals in recovery. By utilizing a SaaS business model, Behaivior aims to democratize mental health recovery and support, assisting users in maintaining their wellness while enabling care providers to enhance their service delivery. Through its proactive approach, Behaivior seeks to improve mental health outcomes and reduce crisis events associated with addiction.

Founded in 2010, VaxForm specializes in vaccine formulation development services. It supports clients from project definition to implementation, focusing on bacterial or viral antigen formulations, vaccine combinations, and live attenuated vaccines. The company also assists in regulatory compliance, patent preparation, and scientific publication writing.

spotLESS Materials LLC is a company based in State College, Pennsylvania, founded in 2018. It specializes in the manufacture and marketing of liquid-entrenched smooth surface (LESS) coatings that make cleaning easier. The company's innovative products include bio-inspired coatings that are liquid and sludge-repellent, designed to simplify the cleaning process for various surfaces, including households and vehicles. By using these coatings, customers can maintain cleanliness more efficiently, reducing water consumption and cleaning costs. The research team at spotLESS Materials comprises professionals in materials, mechanical, and bio-inspired engineering, who engage in collaborative projects to explore materials and engineering solutions that address specific industry challenges and global concerns. The company's products are available for purchase online.

Strados Labs, LLC is a medical technology company based in Philadelphia, Pennsylvania, specializing in respiratory health management through innovative sensor-based solutions. Founded in 2016, the company has developed a wearable device that provides real-time insights into breathing patterns, sounds, and speed. This device is equipped with clinical-grade biosensors and smart software, allowing for continuous monitoring of respiratory conditions such as asthma and chronic obstructive pulmonary disease. By connecting to a mobile application, Strados enables users and healthcare providers to access and analyze respiratory data, facilitating informed health decisions and remote patient monitoring.

Mapless AI is a technology company based in Pittsburgh, Pennsylvania. It specializes in developing safe alternatives for transportation systems, focusing on autonomous driving applications.

Forest Devices, Inc. is a medical device company based in Pittsburgh, Pennsylvania, with an additional office in Canada. Founded in 2014, the company specializes in developing innovative solutions for stroke detection. Its flagship product, AlphaStroke, is a portable and non-invasive stroke screening device that assists medical personnel in identifying early signs of both ischemic and hemorrhagic strokes. By enabling pre-hospital providers to accurately assess patients, AlphaStroke facilitates timely triage and enhances decision-making in critical care scenarios, ultimately aiming to reduce treatment delays and improve patient outcomes.

Interphase Materials, established in 2015 and headquartered in Pittsburgh, Pennsylvania, specializes in developing advanced surface treatment technologies. The company's primary focus is to enhance the efficiency of industrial cooling systems, serving a diverse range of clients including power plants, commercial and industrial HVAC systems, international heat exchanger manufacturers, and the U.S. Navy. Interphase's signature Heat Transfer Enhancement (HTE) system has demonstrated the potential to increase heat exchanger efficiency by 5-10% in initial tests, thereby reducing maintenance costs and improving overall system performance.

Aqueduct Fluidics develops benchtop automation solutions for physical and life sciences research. Founded in 2019 and headquartered in Philadelphia, Pennsylvania, the company provides a software platform that streamlines workflows, integrates hardware components, and accelerates the development of benchtop-scale applications. The platform enables automation scripting and offers an interface to control and visualize hardware status while handling system integration tasks such as communication protocols, timing, user interfaces, and data persistence. By combining software tools with hardware control, Aqueduct Fluidics helps researchers design, test, and deploy automated experimental workflows with greater reliability and efficiency.

NeuroFlow, Inc. is a digital health company that develops a cloud-based platform designed to enhance access to behavioral health and engage patients throughout the continuum of mental healthcare. Founded in 2016 and headquartered in Philadelphia, Pennsylvania, NeuroFlow provides healthcare providers with tools for remote patient monitoring and integration of behavioral health across various care settings, including psychology, primary care, and pain management. The platform employs evidence-based practices to track, assess, and engage patients, promoting overall wellness and improving compliance with treatment. By utilizing patient-generated questionnaires and journaling, NeuroFlow enables individuals to monitor their mental health outcomes and achieve tangible progress. The company has established strategic partnerships with organizations like Smart Health Innovation Lab and Mental Health America to further its mission of improving mental health support and outcomes.

ESTAT Actuation is a company founded in 2019 and based in Pittsburgh, Pennsylvania, that specializes in the development of electroadhesive clutches. These innovative clutches are designed to enhance the performance of robots and machinery by reducing the size and cost of actuators. By providing engineers with lightweight and low-power actuation hardware, ESTAT Actuation enables clients to improve the capabilities and affordability of their robotic systems and machines.

AnkyrBio, headquartered in Pittsburgh, Pennsylvania, is a biotechnology company specializing in the development of a proprietary drug delivery system. This system enhances the efficacy of therapies in wet epithelial areas by enabling therapeutics to be administered as eye drops, remaining active on the eye's surface, and providing localized treatment, extended drug duration, and reduced systemic toxicity.

New York residents looking for a preparatory education that will prepare them for gainful employment or for higher education do not have to look any further than the North Hampton Community College in Bethlehem, New York. North Hampton maintains an open-door admissions policy so that students from varying educational backgrounds can be considered for enrollment, as long as they have earned a high school diploma or GED. The college understands that much of your maturation happens outside the classroom, which is why it offers plenty of college life opportunities. From its residential housing community to emerging leader seminars to a variety of student clubs and organizations, you will be able to find the friends and opportunities for personal, social and professional development. North Hampton offers academics in more than 100 areas of study. Students have the option of pursuing certificates, diplomas or associate’s degrees in many fields, some of which include: * Biotechnology * Journalism * Early Childhood Education * Small Business Management * Theatre A variety of foundational scholarships are awarded to students who meet need or merit qualifications. Other forms of financial aid North Hampton is authorized to offer include federal grants, loans and work-study programs. Tuition costs vary by residency. Students from a sponsored Bethlehem school district, Monroe County district or the state of Pennsylvania receive discounted prices.

Avisi Technologies Inc. is a Philadelphia-based company founded in 2017 that specializes in developing innovative solutions for glaucoma treatment. Its primary product, VisiPlate, is a next-generation, nanotechnology-enabled aqueous shunt designed to prevent blindness caused by glaucoma. Through its advanced technology, Avisi Technologies aims to enhance the effectiveness of glaucoma management and improve patient outcomes.

Founded in 2017, Thermaquil is a medical device company based in Philadelphia, Pennsylvania. It specializes in developing non-invasive, drug-free solutions to manage severe pain and other conditions caused by overactive nerves.

H Quest Vanguard develops plasma conversion processes to produce fuels, chemicals, and advanced carbon materials. The company was founded in 2014 and is based in Pittsburgh, Pennsylvania.

Learnics is a digital learning platform established in 2017 and headquartered in East Stroudsburg, Pennsylvania. The company focuses on equipping educators with tools to gain insights into students' online learning behaviors, thereby enhancing the teaching and learning experience. Learnics' platform supports schools in their transition to digital education by revealing students' online experiences. It allows teachers to guide students during research assignments, emphasizing the significance of the learning process alongside the final outcomes. Through its tools, the platform enables the creation of classes and assignments where learners can log their online research activities, capturing targeted records of student engagement and performance in a digital environment.

Precision Neuroscopics is a medical device company headquartered in Pittsburgh, Pennsylvania, specializing in the development of advanced high-density electroencephalography (EEG) systems. The company focuses on creating innovative technologies that enable the non-invasive detection of brain signals, particularly those indicative of worsening traumatic brain injury. By engineering high-density and user-friendly brain recording systems, Precision Neuroscopics aims to enhance the quality of EEG signal recording while reducing clinical time and costs for healthcare providers.

SpIntellx, Inc. is a computational and systems pathology company based in Pittsburgh, Pennsylvania, that specializes in spatial intelligence software products designed for analyzing pathology tissue sections in cancer diagnosis. Founded in 2017, the company offers innovative solutions such as SpIntellx, which processes image data sets from various imaging platforms and reagents, and HistoMapr, a computational guide for pathologists. Additionally, TumorMapr is utilized to analyze the spatial interactions of biomarkers within whole slide images using multiplexed fluorescence. With a focus on Precision Pathology and Spatially Intelligent Biology, SpIntellx leverages unbiased spatial analytics powered by explainable AI to enhance understanding of complex cancer biology, thereby facilitating advancements in drug development, diagnostics, and treatment strategies.

spotLESS Materials LLC is a company based in State College, Pennsylvania, founded in 2018. It specializes in the manufacture and marketing of liquid-entrenched smooth surface (LESS) coatings that make cleaning easier. The company's innovative products include bio-inspired coatings that are liquid and sludge-repellent, designed to simplify the cleaning process for various surfaces, including households and vehicles. By using these coatings, customers can maintain cleanliness more efficiently, reducing water consumption and cleaning costs. The research team at spotLESS Materials comprises professionals in materials, mechanical, and bio-inspired engineering, who engage in collaborative projects to explore materials and engineering solutions that address specific industry challenges and global concerns. The company's products are available for purchase online.

Founded in 2010, VaxForm specializes in vaccine formulation development services. It supports clients from project definition to implementation, focusing on bacterial or viral antigen formulations, vaccine combinations, and live attenuated vaccines. The company also assists in regulatory compliance, patent preparation, and scientific publication writing.

OsciFlex LLC, established in 2017 and headquartered in Philadelphia, Pennsylvania, specializes in developing a medical device aimed at preventing blood clots from forming at valves. The company's innovative product mimics nature's process to provide more effective compression therapy, reducing the risk of Venous thromboembolism (VTE) in patients and potentially decreasing reliance on costly and risky anti-coagulation pharmaceuticals.

Equilibria Leadership Consulting, established in 2007 and headquartered in Philadelphia, Pennsylvania, specializes in leadership and organizational development. The firm provides a range of services including executive coaching, leadership development, and organizational assessment. Focused on enhancing workplace culture, Equilibria offers tailored training programs and development initiatives designed to improve leadership effectiveness and foster organizational growth. Through its comprehensive approach, the company aims to support individuals and teams in achieving their full potential within various organizational settings.

Behaivior LLC is a digital health company based in Pittsburgh, Pennsylvania, focused on predicting and preventing addiction relapses through innovative technology. Founded in 2017, Behaivior integrates wearable devices with machine learning algorithms to analyze real-time data from various physiological metrics, such as heart rate and skin temperature. The company’s platform, known as Recovery, employs this data to deliver timely interventions tailored to the needs of individuals in recovery. By utilizing a SaaS business model, Behaivior aims to democratize mental health recovery and support, assisting users in maintaining their wellness while enabling care providers to enhance their service delivery. Through its proactive approach, Behaivior seeks to improve mental health outcomes and reduce crisis events associated with addiction.

Dynalene is a developer and supplier of industrial heat transfer fluids and coolants for ultra-low temperature cryogenic and other demanding applications. The company offers glycols, potassium formate, calcium chloride-based secondary refrigerants, and high-performance coolants, along with a range of high- and low-temperature fluids, nanodiamond products, and functionalized nanoparticle dispersions for water treatment, coatings, biomedical, and related uses. It provides laboratory services such as thermal and physical analysis, chemical testing, and materials/corrosion testing. Dynalene serves markets including fuel cells, solar and geothermal, HVAC, supermarket refrigeration, plastics processing, electronics, pharmaceutical, environmental testing, food and beverage, and wind tunnels, and markets its products via an online store. Based in Whitehall, Pennsylvania, the company focuses on cryogenic and precision cooling needs with chemistries spanning glycols, potassium formate, calcium chloride, hydrocarbons, and silicones.

BirdBrain Technologies LLC is a Pittsburgh-based company dedicated to fostering creativity and computational thinking among students and educators. They design and manufacture educational robotics products such as the Finch Robot and Hummingbird Robotics Kit. The Finch is a small, programmable robot designed to inspire learning in computer science, while the Hummingbird enables students to create and program robots using electronic components and craft materials. BirdBrain's products have been used by tens of thousands of students worldwide for various projects, including coding exploration, poetry creation, robot petting zoos, and combined physical-virtual games. The company aims to support educators introducing or advancing computer science, engineering, and making activities in classrooms.

NeuroFlow, Inc. is a digital health company that develops a cloud-based platform designed to enhance access to behavioral health and engage patients throughout the continuum of mental healthcare. Founded in 2016 and headquartered in Philadelphia, Pennsylvania, NeuroFlow provides healthcare providers with tools for remote patient monitoring and integration of behavioral health across various care settings, including psychology, primary care, and pain management. The platform employs evidence-based practices to track, assess, and engage patients, promoting overall wellness and improving compliance with treatment. By utilizing patient-generated questionnaires and journaling, NeuroFlow enables individuals to monitor their mental health outcomes and achieve tangible progress. The company has established strategic partnerships with organizations like Smart Health Innovation Lab and Mental Health America to further its mission of improving mental health support and outcomes.

Verix Health is a medical device company focused on creating a range of actively steerable surgical instruments designed for minimally invasive diagnosis and treatment of challenging lesions in hard-to-reach areas of the human body. Founded by Professor Mark Yim, PhD, in collaboration with PCI Ventures at the University of Pennsylvania, the company is incubated at the Pennovation Center in Philadelphia. Verix Health's innovative devices aim to enhance access and control during surgical procedures, allowing for precise targeting of tumors that are difficult to reach, thereby facilitating minimally invasive treatment options for patients with unfavorable tumor locations.

Instadiagnostics Inc. is a company based in Philadelphia, Pennsylvania, that focuses on developing a point-of-care (POC) diagnostic platform. Founded in 2015, the platform aims to bring centralized laboratory testing directly to patients at their bedside, facilitating early diagnosis and treatment monitoring. This innovative approach allows patients to receive timely medical care in various settings, including primary care centers, community clinics, and emergency departments, without the need for additional trips to have blood drawn or enduring long wait times for results. By streamlining the diagnostic process, Instadiagnostics seeks to enhance patient care and satisfaction, reduce the frequency of medical visits, and ultimately lower overall healthcare costs.

Amriton is a water treatment technology company founded in 2014 and headquartered in Philadelphia, Pennsylvania. The company specializes in developing innovative solutions to remove harmful pollutants from water, utilizing a unique method that incorporates polymer-coated sand to effectively eliminate organic contaminants. Amriton's focus is on creating efficient water treatment processes that facilitate the recycling and reuse of water, thereby promoting sustainability. By providing clients with novel, low-cost, reusable filters, Amriton aims to enhance water purification efforts and contribute to environmental improvement.

LumiShield Technologies develops and supplies sustainable metal oxide coatings that protect metal substrates from corrosion and enhance paint adhesion. Its flagship product, Lumidize®, is an aluminum oxide coating applied via electroplating that can be used on a wide range of metal substrates and multi‑metal components. The technology improves durability, reduces manufacturing costs, and eliminates many environmental problems associated with conventional pretreatment processes. The company serves industries such as automotive, aerospace, marine, electronics, and infrastructure, providing solutions that extend the life of metal parts and vessels used in chemical and other demanding environments.

Cognitive Operational Systems, LLC is an information technology company based in Philadelphia, Pennsylvania, specializing in inventory management solutions for the retail sector. Established in 2012, the company utilizes advanced robotics powered by computer vision and artificial intelligence to navigate retail environments. Its technology not only manages inventory and ensures compliance with planograms and promotions but also provides indoor localization and turn-by-turn navigation. Additionally, Cognitive Operational Systems maps retail layouts and architecture, integrating university research to develop practical industry applications in machine perception and software as a service.

BirdBrain Technologies LLC is a Pittsburgh-based company dedicated to fostering creativity and computational thinking among students and educators. They design and manufacture educational robotics products such as the Finch Robot and Hummingbird Robotics Kit. The Finch is a small, programmable robot designed to inspire learning in computer science, while the Hummingbird enables students to create and program robots using electronic components and craft materials. BirdBrain's products have been used by tens of thousands of students worldwide for various projects, including coding exploration, poetry creation, robot petting zoos, and combined physical-virtual games. The company aims to support educators introducing or advancing computer science, engineering, and making activities in classrooms.

Guiding Technologies Corporation develops GAINS, a guidance and assessment platform for applied behavior analysis. GAINS serves as a virtual assistant for supervisors and staff, enabling efficient program selection, data collection, progress tracking across programs, and automated data capture, while providing audit trails and tools to support parental involvement and organizational insight. The platform combines a web-based management console, an instructor interface on smartphones or tablets using a Bluetooth earpiece for staff guidance, and cloud-based storage of data, program information, and student databases. Founded in 2013, the company is based in Philadelphia, Pennsylvania.

BioSignal Analytics is a healthcare technology company headquartered in Philadelphia, Pennsylvania, focused on enhancing healthcare quality through automated interpretation technology. Utilizing advanced machine learning algorithms, the company has developed a decision-support tool that integrates seamlessly into the clinical workflow of neurologists. This tool leverages extensive big data resources to train sophisticated models that can self-organize information and uncover underlying patterns. By providing real-time seizure detection alerts, BioSignal Analytics aims to support healthcare professionals in delivering timely and effective patient care.

Instadiagnostics Inc. is a company based in Philadelphia, Pennsylvania, that focuses on developing a point-of-care (POC) diagnostic platform. Founded in 2015, the platform aims to bring centralized laboratory testing directly to patients at their bedside, facilitating early diagnosis and treatment monitoring. This innovative approach allows patients to receive timely medical care in various settings, including primary care centers, community clinics, and emergency departments, without the need for additional trips to have blood drawn or enduring long wait times for results. By streamlining the diagnostic process, Instadiagnostics seeks to enhance patient care and satisfaction, reduce the frequency of medical visits, and ultimately lower overall healthcare costs.

Dynalene is a developer and supplier of industrial heat transfer fluids and coolants for ultra-low temperature cryogenic and other demanding applications. The company offers glycols, potassium formate, calcium chloride-based secondary refrigerants, and high-performance coolants, along with a range of high- and low-temperature fluids, nanodiamond products, and functionalized nanoparticle dispersions for water treatment, coatings, biomedical, and related uses. It provides laboratory services such as thermal and physical analysis, chemical testing, and materials/corrosion testing. Dynalene serves markets including fuel cells, solar and geothermal, HVAC, supermarket refrigeration, plastics processing, electronics, pharmaceutical, environmental testing, food and beverage, and wind tunnels, and markets its products via an online store. Based in Whitehall, Pennsylvania, the company focuses on cryogenic and precision cooling needs with chemistries spanning glycols, potassium formate, calcium chloride, hydrocarbons, and silicones.

Digital Dream Labs is an education technology company focused on hands-on learning for children aged 4 to 9. It develops engaging, language- and system-agnostic products that enable pre-readers to interact with on-screen environments and with devices such as educational robots, smart speakers, other smart devices, and drones. The company was founded in 2012 and is headquartered in Pittsburgh, Pennsylvania.

Syandus Inc., established in 2001 and headquartered in Exton, Pennsylvania, specializes in intelligent simulation learning technology tailored for the pharmaceutical industry. The company offers two primary products: Virtual Conventions, which employs responsive technology to engage patients, and Medical Scenario Simulator, enabling clinicians to practice clinical decision-making virtually. Syandus' platform facilitates promotional experiential learning and multichannel marketing for pharmacies, aiming to increase sales, modify prescription behaviors, and enhance doctor reach. The company's vision is to transform life science and medical concept learning for healthcare professionals, students, and patients through innovative technology and modern learning principles.

PolyK Technologies is a high-tech company that focuses on high-voltage dielectrics, piezoelectric materials, and smart materials, and test instruments and applications. PolyK is based in State College, Pennsylvania, which is home to Penn State University's dielectric and piezoelectric technology.

LumiShield Technologies develops and supplies sustainable metal oxide coatings that protect metal substrates from corrosion and enhance paint adhesion. Its flagship product, Lumidize®, is an aluminum oxide coating applied via electroplating that can be used on a wide range of metal substrates and multi‑metal components. The technology improves durability, reduces manufacturing costs, and eliminates many environmental problems associated with conventional pretreatment processes. The company serves industries such as automotive, aerospace, marine, electronics, and infrastructure, providing solutions that extend the life of metal parts and vessels used in chemical and other demanding environments.

Ascent Bio-Nano Technologies develops and commercializes acoustofluidic chips and instruments for research, diagnostic, and therapeutic applications. Its core competency lies in rapid prototype development of acoustofluidic chips for sample preparation, separation, and manipulation of bioparticles such as cells and vesicles, and bioanalysis.

Amriton is a water treatment technology company founded in 2014 and headquartered in Philadelphia, Pennsylvania. The company specializes in developing innovative solutions to remove harmful pollutants from water, utilizing a unique method that incorporates polymer-coated sand to effectively eliminate organic contaminants. Amriton's focus is on creating efficient water treatment processes that facilitate the recycling and reuse of water, thereby promoting sustainability. By providing clients with novel, low-cost, reusable filters, Amriton aims to enhance water purification efforts and contribute to environmental improvement.

Longevity Biotech, Inc. is a biopharmaceutical company based in Philadelphia, Pennsylvania, that specializes in developing innovative therapeutic drug candidates through its proprietary Hybridtide peptide technology. Founded in 2010, the company focuses on creating customizable peptides that offer enhanced stability and absorption for various biological environments. Its product pipeline includes LBT-3627, a novel neuroprotective agent aimed at treating disorders such as Parkinson’s disease; LBT-6030, a dual agonist targeting glucagon for metabolic conditions; and LBT-5001, a fusion inhibitor among other oncology and cholesterol-related products. Additionally, Longevity Biotech is engaged in clinical studies to identify immune and inflammatory markers potentially useful for diagnosing Parkinson's disease, further underscoring its commitment to addressing significant medical needs.

PolyK Technologies is a high-tech company that focuses on high-voltage dielectrics, piezoelectric materials, and smart materials, and test instruments and applications. PolyK is based in State College, Pennsylvania, which is home to Penn State University's dielectric and piezoelectric technology.

Guiding Technologies Corporation develops GAINS, a guidance and assessment platform for applied behavior analysis. GAINS serves as a virtual assistant for supervisors and staff, enabling efficient program selection, data collection, progress tracking across programs, and automated data capture, while providing audit trails and tools to support parental involvement and organizational insight. The platform combines a web-based management console, an instructor interface on smartphones or tablets using a Bluetooth earpiece for staff guidance, and cloud-based storage of data, program information, and student databases. Founded in 2013, the company is based in Philadelphia, Pennsylvania.

ATRP SOLUTIONS develops and manufactures specialty polymers that meet their needs. It recognizes the polymeric materials for improving the performance of commercial products in the areas of personal care and cosmetics, detergents and surfactants, paints, pigments, coatings, and biocompatible materials. It was founded in 2006 and is headquartered in Pittsburgh, Pennsylvania.

ZSX Medical is a medical device development company based in Philadelphia, Pennsylvania, founded in 2009. The company specializes in creating bio-absorbable products for internal closure in minimally invasive surgeries. Their flagship product, Zip-stitch, is a surgical closure system designed to simplify and expedite difficult surgical closures, particularly for uterine closure during cesarean deliveries. By reducing operative time and potential complications such as infection and tissue adhesion, ZSX Medical aims to improve patient outcomes and lower healthcare costs for hospitals.

Founded in 2013, Impulse Technology specializes in nanofabrication and MEMS design. It offers thin film specimens for micro-electrodes and heaters, along with research services in thermoelectric energy conversion. The company also develops therapeutic devices, including a prosthetic leg component.

Citrine Informatics, Inc. is a software company based in Redwood City, California, with an additional office in Pittsburgh, Pennsylvania, founded in 2013. It specializes in materials informatics by developing an artificial intelligence platform that aggregates extensive data on materials, chemicals, and devices. This platform leverages machine learning and data science to enhance research and development, manufacturing, and supply chain operations for organizations involved in producing physical products. By streamlining the materials development process, Citrine Informatics aims to facilitate the discovery of new materials and reduce defects early in the research phase, thus improving product growth and design. The company's focus spans various sectors, including energy, aerospace, and electronics.

Actuated Medical, Inc. is a medical device company based in Bellefonte, Pennsylvania, that focuses on designing, developing, and manufacturing innovative solutions for healthcare. Established in 2006, the company specializes in devices that facilitate occlusion clearing, tissue penetration, and MRI-guided surgical procedures. Their product line includes systems like TubeClear and NG-Clear, which are designed to clear clogs in feeding tubes, as well as devices for controlled tissue penetration, such as the GentleSharp Device and OsteoAccess System. Additionally, Actuated Medical offers MRI-compatible technologies, including direct drive piezoelectric ultrasonic motors that enhance diagnostic and surgical capabilities during imaging procedures. The company's commitment to improving patient care is reflected in their range of minimally invasive instruments and transdermal delivery systems. Actuated Medical was previously known as Piezo Resonance Innovations, Inc. before rebranding in September 2011.

LimoLink, Inc. is a provider of ground chauffeured services, specializing in private aviation, executive travel, meetings, events, roadshows, and travel agencies. Established in 1998 and headquartered in Marion, Iowa, the company maintains additional account management offices in major cities including New York, Chicago, Atlanta, Philadelphia, and London. LimoLink aims to deliver a reliable and consistent worldwide solution for chauffeured ground transportation, enhanced by dedicated account management, reservation management, and advanced technology.

PolyK Technologies is a high-tech company that focuses on high-voltage dielectrics, piezoelectric materials, and smart materials, and test instruments and applications. PolyK is based in State College, Pennsylvania, which is home to Penn State University's dielectric and piezoelectric technology.

Longevity Biotech, Inc. is a biopharmaceutical company based in Philadelphia, Pennsylvania, that specializes in developing innovative therapeutic drug candidates through its proprietary Hybridtide peptide technology. Founded in 2010, the company focuses on creating customizable peptides that offer enhanced stability and absorption for various biological environments. Its product pipeline includes LBT-3627, a novel neuroprotective agent aimed at treating disorders such as Parkinson’s disease; LBT-6030, a dual agonist targeting glucagon for metabolic conditions; and LBT-5001, a fusion inhibitor among other oncology and cholesterol-related products. Additionally, Longevity Biotech is engaged in clinical studies to identify immune and inflammatory markers potentially useful for diagnosing Parkinson's disease, further underscoring its commitment to addressing significant medical needs.

Ascent Bio-Nano Technologies develops and commercializes acoustofluidic chips and instruments for research, diagnostic, and therapeutic applications. Its core competency lies in rapid prototype development of acoustofluidic chips for sample preparation, separation, and manipulation of bioparticles such as cells and vesicles, and bioanalysis.

CEINT is a collaborative research center headquartered at Duke University, investigating the environmental implications of nanomaterials. It explores their potential exposure, biological effects, and ecological impacts, involving researchers from multiple universities and international partners.

PolyK Technologies is a high-tech company that focuses on high-voltage dielectrics, piezoelectric materials, and smart materials, and test instruments and applications. PolyK is based in State College, Pennsylvania, which is home to Penn State University's dielectric and piezoelectric technology.

Carnegie Mellon University is a renowned private research university, offering undergraduate and graduate programs across diverse fields, with a strong focus on technology and arts. It is particularly distinguished for its School of Computer Science, recognized globally for its research and education, and the Heinz College of Information Systems and Public Policy, which uniquely combines management and policy expertise. The university serves various sectors, including education, technology, and the arts, contributing significantly to these fields through its academic programs and research.

Health Fidelity, Inc. is a technology-driven company based in San Mateo, California, specializing in risk adjustment solutions for healthcare organizations participating in Medicare Advantage, Medicaid, and Accountable Care Organization programs. Founded in 2011, the company utilizes advanced natural language processing technology to analyze clinical documentation, enabling the identification of hidden risk factors and extraction of critical insights from medical charts. Health Fidelity's offerings include a comprehensive risk adjustment solution that transforms the manual risk adjustment process into an integrated workflow, as well as Risk Analytics, which optimizes return on investment and identifies care gaps. Their HF360 Compliance solution further ensures accurate risk adjustment results and minimizes audit risks. By providing clear visibility and control over the risk adjustment process, Health Fidelity empowers organizations to enhance care planning and improve revenue capture in risk-sharing arrangements. The company operates as a subsidiary of the University of Pittsburgh Medical Center.

Founded in 1787, the University of Pittsburgh is a renowned research university offering professional medical education through its School of Medicine since 1886. It is ranked No. 24 worldwide and No. 9 among U.S. public universities.

ZSX Medical is a medical device development company based in Philadelphia, Pennsylvania, founded in 2009. The company specializes in creating bio-absorbable products for internal closure in minimally invasive surgeries. Their flagship product, Zip-stitch, is a surgical closure system designed to simplify and expedite difficult surgical closures, particularly for uterine closure during cesarean deliveries. By reducing operative time and potential complications such as infection and tissue adhesion, ZSX Medical aims to improve patient outcomes and lower healthcare costs for hospitals.

Love Park Robotics is a Philadelphia-based start-up that specializes in developing advanced technologies for intelligent products and services. The company's flagship platform, CoPilot, offers sliding-scale autonomous navigation for service vehicles in both indoor and dynamic outdoor environments. Love Park Robotics focuses on creating 3D perception software and advanced driver assistance systems that facilitate autonomous navigation, particularly addressing challenges such as automotive access for wheelchair users. By providing flexible licensing options and customizable solutions, the company collaborates with original equipment manufacturers (OEMs) to integrate its innovative technology into cutting-edge products and services, enabling industries to develop robots that can intelligently interact with their surroundings.

Actuated Medical, Inc. is a medical device company based in Bellefonte, Pennsylvania, that focuses on designing, developing, and manufacturing innovative solutions for healthcare. Established in 2006, the company specializes in devices that facilitate occlusion clearing, tissue penetration, and MRI-guided surgical procedures. Their product line includes systems like TubeClear and NG-Clear, which are designed to clear clogs in feeding tubes, as well as devices for controlled tissue penetration, such as the GentleSharp Device and OsteoAccess System. Additionally, Actuated Medical offers MRI-compatible technologies, including direct drive piezoelectric ultrasonic motors that enhance diagnostic and surgical capabilities during imaging procedures. The company's commitment to improving patient care is reflected in their range of minimally invasive instruments and transdermal delivery systems. Actuated Medical was previously known as Piezo Resonance Innovations, Inc. before rebranding in September 2011.

ATRP SOLUTIONS develops and manufactures specialty polymers that meet their needs. It recognizes the polymeric materials for improving the performance of commercial products in the areas of personal care and cosmetics, detergents and surfactants, paints, pigments, coatings, and biocompatible materials. It was founded in 2006 and is headquartered in Pittsburgh, Pennsylvania.

Health Fidelity, Inc. is a technology-driven company based in San Mateo, California, specializing in risk adjustment solutions for healthcare organizations participating in Medicare Advantage, Medicaid, and Accountable Care Organization programs. Founded in 2011, the company utilizes advanced natural language processing technology to analyze clinical documentation, enabling the identification of hidden risk factors and extraction of critical insights from medical charts. Health Fidelity's offerings include a comprehensive risk adjustment solution that transforms the manual risk adjustment process into an integrated workflow, as well as Risk Analytics, which optimizes return on investment and identifies care gaps. Their HF360 Compliance solution further ensures accurate risk adjustment results and minimizes audit risks. By providing clear visibility and control over the risk adjustment process, Health Fidelity empowers organizations to enhance care planning and improve revenue capture in risk-sharing arrangements. The company operates as a subsidiary of the University of Pittsburgh Medical Center.

PolyK Technologies is a high-tech company that focuses on high-voltage dielectrics, piezoelectric materials, and smart materials, and test instruments and applications. PolyK is based in State College, Pennsylvania, which is home to Penn State University's dielectric and piezoelectric technology.

Carley Technologies, established in 2007 in Sewickley, Pennsylvania, specializes in social network analysis and wireless communications. The company focuses on analyzing dynamic meta-networks and offers strategies for social network development, as well as communication networks and wireless network solutions. Carley Technologies provides services that assist in research related to social network-aware wireless communications, including programmable RF cognitive radios, to enhance communication services for its clients.

nanoGriptech, Inc. is a Pittsburgh-based company founded in 2012 that specializes in the manufacture of micro-fibrillar polymer-based dry adhesives and surfaces. Its key product offerings include Setex Gecko Tape, a reusable, residue-free tape, and the Setex Ultra-Thin Fastener, designed for seamless integration with smooth surfaces. The company draws inspiration from nature, mimicking the adhesion mechanism of gecko feet to create durable, versatile adhesives suitable for a wide range of applications. These include wearables, sports equipment, semiconductors, robotics, medical devices, automotive, and packaging. With a focus on innovation, nanoGriptech has established partnerships with several multinational corporations and has recently initiated its first sales in the high-friction clothing material market.

Actuated Medical, Inc. is a medical device company based in Bellefonte, Pennsylvania, that focuses on designing, developing, and manufacturing innovative solutions for healthcare. Established in 2006, the company specializes in devices that facilitate occlusion clearing, tissue penetration, and MRI-guided surgical procedures. Their product line includes systems like TubeClear and NG-Clear, which are designed to clear clogs in feeding tubes, as well as devices for controlled tissue penetration, such as the GentleSharp Device and OsteoAccess System. Additionally, Actuated Medical offers MRI-compatible technologies, including direct drive piezoelectric ultrasonic motors that enhance diagnostic and surgical capabilities during imaging procedures. The company's commitment to improving patient care is reflected in their range of minimally invasive instruments and transdermal delivery systems. Actuated Medical was previously known as Piezo Resonance Innovations, Inc. before rebranding in September 2011.

DVIRC is a leading private, non-profit economic development organization established in 1988 to serve the needs of nearly 5,000 Small to Midsized advanced manufacturing Enterprises (SME) in five counties throughout the Philadelphia region. The organization's primary focus is to grow business value for clients through consulting services, talent development and regional, state and federal resource assistance, helping to establish the region as an internationally recognized leader in manufacturing competitiveness. We believe growing business value improves the standard of living and quality of life for those that live and/or work in the region. A diverse board of directors comprised of executives from the manufacturing, banking, legal and economic development communities govern the DVIRC.