National Science Foundation

The National Science Foundation (NSF) is an independent federal agency established in 1950 and based in Alexandria, Virginia. It is dedicated to supporting research and education in science and engineering across a wide range of disciplines. The NSF provides significant non-dilutive funding, up to $1.5 million, to startups and small businesses through its America's Seed Fund initiative, which is part of the Small Business Innovation Research (SBIR) program mandated by Congress. With an operating budget of approximately $7.8 billion, the NSF is committed to advancing fundamental research and education, thus fostering innovation and technological development in the United States.

James Donlon

Program Director

Debasis Majumdar

Program Director

Graciela Narcho

Staff Associate

Sethuraman Panchanathan

Director

Past deals in Pennsylvania

University of Pennsylvania

Grant in 2024
The University of Pennsylvania, founded nearly 250 years ago, is a prestigious Ivy League institution known for its rigorous academic programs and commitment to research. It offers a wide array of undergraduate, graduate, and professional degrees across various fields, including liberal arts, sciences, and specialized disciplines. The university features over 140 undergraduate programs and more than 180 graduate options, fostering a vibrant intellectual community. Additionally, the Perelman School of Medicine, the oldest medical school in the United States, plays a crucial role in medical education and research, consistently ranking among the top in the nation. Community engagement is emphasized through numerous volunteer programs and academic service courses, reflecting Penn's dedication to public service. Admission to the university is highly competitive, requiring standardized test scores and a completed application. Financial aid is awarded based on need, with the university striving to provide packages without loans, ensuring accessibility for all students.

University of Pennsylvania

Grant in 2023
The University of Pennsylvania, founded nearly 250 years ago, is a prestigious Ivy League institution known for its rigorous academic programs and commitment to research. It offers a wide array of undergraduate, graduate, and professional degrees across various fields, including liberal arts, sciences, and specialized disciplines. The university features over 140 undergraduate programs and more than 180 graduate options, fostering a vibrant intellectual community. Additionally, the Perelman School of Medicine, the oldest medical school in the United States, plays a crucial role in medical education and research, consistently ranking among the top in the nation. Community engagement is emphasized through numerous volunteer programs and academic service courses, reflecting Penn's dedication to public service. Admission to the university is highly competitive, requiring standardized test scores and a completed application. Financial aid is awarded based on need, with the university striving to provide packages without loans, ensuring accessibility for all students.

Carnegie Mellon University

Grant in 2023
Carnegie Mellon University is a private research institution renowned for its innovative programs in technology and the arts. It offers a wide array of undergraduate and graduate degrees across diverse disciplines, with a strong emphasis on computer science, information systems, and public policy. The university's Heinz College of Information Systems and Public Policy features highly regarded graduate degree and executive education programs, combining expertise in information systems with public policy management. Additionally, the School of Computer Science is recognized globally as a leading center for research and education in computer science. Through its interdisciplinary approach, Carnegie Mellon University serves various sectors, including education, technology, and the arts, fostering a collaborative environment that prepares students for future challenges.

Elizabethtown College, Elizabethtown

Grant in 2022
If you’re looking for the traditional liberal arts college experience, Elizabethtown College delivers. The private school has an enrollment below 2000, with a student-to-faculty ratio of less than 13:1. Like similar schools, Elizabethtown College’s academics focus on developing writing skills, communication, creativity and critical thinking. However, Elizabethtown’s academics are quite extensive for a school of its size. The college offers over 50 majors and 80 minors leading to a bachelor’s degree. The school has recently begun a master’s degree program in Occupational Therapy, as well. Over 85% of Elizabethtown College students live on-campus, resulting in vibrant student life. Some of Elizabethtown’s residence halls are living-learning communities, which are based on shared academic interests. The college also features a number of student clubs, organizations and service opportunities. Elizabethtown’s admissions process is quite comprehensive. In addition to academic achievements, the college considers an applicant’s integrity, work ethic, level of interest, work experience and extracurricular involvement, to name a few. Your academics are a key point of consideration, but more important is how well you’ll fit with the school. Eligible Elizabethtown College students may receive financial aid. This includes need-based federal financial aid programs as well as institutional merit scholarships. Elizabethtown considers all applicants for merit scholarships as part of the application review.

OsciFlex

Grant in 2021
OsciFlex LLC, founded in 2017 and based in Philadelphia, Pennsylvania, specializes in developing a wearable medical device aimed at preventing blood clots in patients. The device functions by stimulating calf muscle contractions through a muscle stretch reflex, which promotes valve sinus recirculatory flow. This innovative approach helps to prevent venous thromboembolism (VTE), a serious condition that can lead to significant health complications. By offering an alternative to traditional anti-coagulation pharmaceuticals, which can be costly and carry risks, OsciFlex aims to enhance patient care and reduce healthcare costs associated with blood clot management.

MBF Therapeutics

Grant in 2021
MBF Therapeutics, Inc. is a veterinary oncology company that specializes in developing and commercializing innovative therapies for cancer treatment in dogs and cats. The company's product portfolio features targeted immunotherapies and small molecule drugs designed to disrupt tumor cell metabolism while sparing healthy tissues. Key products include MBFT-101, a combination therapy for sarcomas and lymphoma that utilizes a proprietary polyamine transport inhibitor alongside a potent inhibitor of ornithine decarboxylase, and MBFT-102, an immunotherapy based on the tumor suppressor/cytokine mda-7/IL24, which has shown promise in human clinical trials for various advanced cancers. Additionally, MBF Therapeutics is advancing a gene-based vaccine platform aimed at improving treatments for both cancer and infectious diseases in animals, with the potential to transform veterinary medicine. The company is located in Ambler, Pennsylvania, and maintains a strategic partnership with the Lankenau Institute for Medical Research.

Aqueduct Fluidics

Grant in 2021
Aqueduct Fluidics develops automation solutions for physical and life sciences research that fit on a laboratory benchtop. The company was founded in 2019 and is headquartered in Philadelphia, PA.

Precision Neuroscopics

Grant in 2021
Precision Neuroscopics is a medical device company located in Pittsburgh, Pennsylvania, specializing in the development of advanced high-density electroencephalography (EEG) systems. These innovative systems are designed to non-invasively detect brain signals that indicate worsening traumatic brain injuries. The company's focus is on creating engineering technologies that enhance the density, durability, and usability of brain recording systems. By improving the quality of EEG signal recordings, Precision Neuroscopics aims to assist clinicians in reducing clinical time and costs associated with brain monitoring, ultimately enhancing patient care.

Susmax

Grant in 2021
Susmax is a construction company based in Philadelphia, Pennsylvania, that focuses on producing lightweight aggregate for the construction industry. Founded in 2020, the company utilizes thermodynamics-based technology to transform waste coal combustion products into structural lightweight concrete. This innovative approach enhances the workability and extends the service life of concrete, offering a sustainable solution for construction needs.

Workers First

Grant in 2021
Workers First is a research and design company specialized in the creation of innovative materials for worker protection. The corporation was founded in 2016 and is based in Pittsburgh, Pennsylvania.

NeuroTechR3

Grant in 2021
NeuroTechR3 is a biomedical device and digital health start-up that focuses on developing affordable rehabilitation technologies to enhance upper extremity function for individuals affected by brain injuries, including stroke and cerebral palsy. The company's flagship innovation, R3THATM, leverages machine learning and cloud technology to enable personalized telerehabilitation through engaging exergames designed to foster neuroplasticity. This system includes features such as motion tracking, analytics, and real-time biofeedback, which help clinicians provide high-quality, efficient care while improving patient recovery outcomes. Founded in 2020 by a team of four women, NeuroTechR3 emerged from the New Jersey Institute of Technology and Rutgers University, and operates from locations in Newark, NJ, and Philadelphia, PA. The company's expertise lies in biomedical engineering and computer science, positioning it to address the needs of the rehabilitation industry effectively. By advancing rehabilitation devices and machine learning-driven technologies, NeuroTechR3 aims to transform healthcare and make rehabilitation more accessible and sustainable for individuals with various impairments.

Arcadia University Endowment

Grant in 2021
A high ranking from U.S. News and World Report and degree programs not found anywhere else are just some of the reasons to attend Arcadia University. Located in Glenside, Pennsylvania, Arcadia University’s campus features beautiful rolling green hills and historical buildings. It was also ranked as one of the “top up-and-coming” universities in the northeast by U.S. News and World Report and as one of the Northeast’s best colleges by Princeton Review. Arcadia University offers bachelor’s, master’s and doctoral degrees in more than 45 fields which include such distinctive fields as Creative Writing, Religion, Engineering, Fashion Studies, and Veterinary Medicine. Its graduate school offerings are some of the most compelling and unique degree options, including dual degree offerings in such combined fields as Physical Therapy and Public Health. Arcadia is also acknowledged for its international study options, which allow students to study abroad for varying lengths of time. Through career services, students may also apply for internships in their field of study. Financial aid options at Arcadia may be discussed with a financial aid counselor and include loans, grants and scholarships for eligible students.

NeuroTechR3

Grant in 2021
NeuroTechR3 is a biomedical device and digital health start-up that focuses on developing affordable rehabilitation technologies to enhance upper extremity function for individuals affected by brain injuries, including stroke and cerebral palsy. The company's flagship innovation, R3THATM, leverages machine learning and cloud technology to enable personalized telerehabilitation through engaging exergames designed to foster neuroplasticity. This system includes features such as motion tracking, analytics, and real-time biofeedback, which help clinicians provide high-quality, efficient care while improving patient recovery outcomes. Founded in 2020 by a team of four women, NeuroTechR3 emerged from the New Jersey Institute of Technology and Rutgers University, and operates from locations in Newark, NJ, and Philadelphia, PA. The company's expertise lies in biomedical engineering and computer science, positioning it to address the needs of the rehabilitation industry effectively. By advancing rehabilitation devices and machine learning-driven technologies, NeuroTechR3 aims to transform healthcare and make rehabilitation more accessible and sustainable for individuals with various impairments.

Arieca

Grant in 2021
Arieca LLC, established in 2018 and based in Pittsburgh, Pennsylvania, specializes in the development and distribution of Thubber, a thermally conductive rubber composite. This innovative material merges the elasticity of soft silicone rubber with the thermal conductivity of metal, making it suitable for applications such as circuit wiring, sensors, and passive heat exchangers. Arieca's product addresses heat management challenges in various industries, enabling manufacturers to utilize an alternative rubber solution that enhances electronic performance while ensuring safe interaction with human users.

FloBio

Grant in 2020
FloBio develops point-of-care diagnostics for bleeding risk based on real-time blood analysis. The company was founded in 2017 and is headquartered in Philadelphia, PA.

Plexision

Grant in 2020
Plexision develops cellular biomarkers for personalized diagnosis and drug development in solid organ transplantation, and immunological disorders. Plexision's first patented product, the PleximmuneTM assay, predicts the risk of transplant rejection. The test is based on patent-pending technology to measure antigen-specific white blood cells. Testing services for transplant recipients and drug developers are provided at Plexision’s CLIA-certified, central laboratory in Pittsburgh. Plexision currently offers cell-based testing for personalized assessment of rejection risk after solid organ transplantation The Pleximmune blood test is the first such test offered for children with liver or intestine transplantation.

Thermaquil

Grant in 2020
Thermaquil, Inc. is a Philadelphia-based company founded in 2017 that specializes in the development and sale of medical devices aimed at managing pain and other conditions linked to overactive nerves. The company is focused on creating an innovative reversible nerve block device designed to alleviate severe pain without the use of drugs or electrical stimulation, while also ensuring that no nerve damage occurs. This device is intended to provide relief to millions of individuals suffering from chronic pain, muscle spasms, and related ailments, thereby improving their quality of life.

Behaivior

Grant in 2020
Behaivior LLC is a digital health company based in Pittsburgh, Pennsylvania, focused on predicting and preventing addiction relapses through innovative technology. Founded in 2017, Behaivior develops a platform that combines wearable devices and machine learning algorithms to monitor key physiological signals such as heart rate and motion. This system, known as Recovery, is designed to support mental health recovery and wellness by delivering timely interventions based on real-time data. By utilizing a software-as-a-service (SaaS) model, Behaivior empowers individuals to maintain their recovery process while enabling care providers to better assist their clients. The integration of AI and behavioral health technology allows Behaivior to recognize patterns in human behavior, ultimately aiming to enhance mental well-being and reduce the incidence of crises, including relapse.

Strados Labs

Grant in 2020
Strados Labs is a medical technology company that innovates respiratory monitoring using smart biosensors and artificial intelligence. The company specializes in advancing respiratory health management using clinical-grade biosensors and intelligent software. It connects people with real-time respiratory monitoring using a wearable device and connected mobile platform so they can quantify their health and make more informed decisions. The company was founded in 2016 and is headquartered in Philadelphia, Pennsylvania.

Mapless AI

Grant in 2020
Mapless AI is a research company that develops safe alternatives for transportation systems. The company's headquarters are in Pittsburgh, Pennsylvania.

Forest Devices

Grant in 2020
Forest Devices, Inc. is a medical device company based in Pittsburgh, Pennsylvania, with an additional office in Canada. Founded in 2014, the company focuses on developing innovative solutions for stroke detection. Its primary product, AlphaStroke, is a portable and non-invasive stroke screening device that assists medical personnel in identifying early signs of both ischemic and hemorrhagic strokes. This device is designed to be low-cost and durable, enabling pre-hospital providers to triage patients effectively and make timely decisions regarding their care. By improving the speed and accuracy of stroke detection, Forest Devices aims to reduce delays in critical treatment for patients experiencing strokes.

Aqueduct Fluidics

Grant in 2020
Aqueduct Fluidics develops automation solutions for physical and life sciences research that fit on a laboratory benchtop. The company was founded in 2019 and is headquartered in Philadelphia, PA.

NeuroFlow

Grant in 2020
NeuroFlow, Inc. is a digital health company based in Philadelphia, Pennsylvania, that specializes in providing a platform for behavioral health and patient engagement throughout the mental healthcare continuum. Founded in 2016, NeuroFlow offers cloud-based tools designed for remote patient monitoring and the integration of behavioral health across various care settings, including psychology, primary care, and pain management. The platform empowers healthcare providers to track and engage patients through evidence-based practices, enhancing patient compliance and overall wellness. NeuroFlow's solutions cater to a diverse range of stakeholders, including practices, clinics, hospitals, health plans, and individuals. The company collaborates with several strategic partners, such as Smart Health Innovation Lab and Mental Health America, to further its mission of improving mental health outcomes.

Ankyrbio

Grant in 2019
AnkyrBio is a biotechnology company focused on commercializing its proprietary anchoring system. The company is based in Pittsburgh, Pennsylvania.

Northampton Community College, Bethlehem

Grant in 2019
New York residents looking for a preparatory education that will prepare them for gainful employment or for higher education do not have to look any further than the North Hampton Community College in Bethlehem, New York. North Hampton maintains an open-door admissions policy so that students from varying educational backgrounds can be considered for enrollment, as long as they have earned a high school diploma or GED. The college understands that much of your maturation happens outside the classroom, which is why it offers plenty of college life opportunities. From its residential housing community to emerging leader seminars to a variety of student clubs and organizations, you will be able to find the friends and opportunities for personal, social and professional development. North Hampton offers academics in more than 100 areas of study. Students have the option of pursuing certificates, diplomas or associate’s degrees in many fields, some of which include: * Biotechnology * Journalism * Early Childhood Education * Small Business Management * Theatre A variety of foundational scholarships are awarded to students who meet need or merit qualifications. Other forms of financial aid North Hampton is authorized to offer include federal grants, loans and work-study programs. Tuition costs vary by residency. Students from a sponsored Bethlehem school district, Monroe County district or the state of Pennsylvania receive discounted prices.

Avisi Technologies

Grant in 2019
Avisi Technologies Inc. is a company based in Philadelphia, Pennsylvania, that focuses on developing innovative solutions for glaucoma treatment. Founded in 2017, the company has created VisiPlate, a next-generation aqueous shunt that utilizes nanotechnology to provide a defense against blindness caused by glaucoma. This advanced technology aims to improve the effectiveness of glaucoma treatments and enhance patient outcomes.

Thermaquil

Grant in 2019
Thermaquil, Inc. is a Philadelphia-based company founded in 2017 that specializes in the development and sale of medical devices aimed at managing pain and other conditions linked to overactive nerves. The company is focused on creating an innovative reversible nerve block device designed to alleviate severe pain without the use of drugs or electrical stimulation, while also ensuring that no nerve damage occurs. This device is intended to provide relief to millions of individuals suffering from chronic pain, muscle spasms, and related ailments, thereby improving their quality of life.

Learnics

Grant in 2019
Learnics provides tools that enable teachers to gather vital information about their students' online learning behaviors. The company was founded in 2017 and is based in East Stroudsburg, Pennsylvania.

Precision Neuroscopics

Grant in 2019
Precision Neuroscopics is a medical device company located in Pittsburgh, Pennsylvania, specializing in the development of advanced high-density electroencephalography (EEG) systems. These innovative systems are designed to non-invasively detect brain signals that indicate worsening traumatic brain injuries. The company's focus is on creating engineering technologies that enhance the density, durability, and usability of brain recording systems. By improving the quality of EEG signal recordings, Precision Neuroscopics aims to assist clinicians in reducing clinical time and costs associated with brain monitoring, ultimately enhancing patient care.

SpIntellx

Grant in 2019
SpIntellx, Inc. is a computational and systems pathology company based in Pittsburgh, Pennsylvania, specializing in spatial intelligence software products for cancer diagnosis. Established in 2017, the company offers innovative solutions such as SpIntellx, which analyzes image data sets from various imaging platforms and reagent types, enabling precise analysis of pathology tissue sections. Additionally, SpIntellx provides HistoMapr, a computational guide for pathologists, and TumorMapr, which examines the spatial interactions of biomarkers within whole slide images using multiplexed fluorescence. By leveraging unbiased spatial analytics powered by explainable AI, SpIntellx aims to enhance the understanding of complex cancer biology, contributing to advancements in medicine and research across drug development, diagnostics, and treatment pipelines.

spotLESS Materials

Grant in 2019
spotLESS Materials LLC is a manufacturer based in State College, Pennsylvania, specializing in innovative cleaning solutions through its liquid-entrenched smooth surface (LESS) coatings. Founded in 2018, the company provides nature-inspired coatings that repel dirt and grime, including liquid and sludge-repellent products designed to keep surfaces clean for extended periods. These coatings aim to simplify the cleaning process for households and vehicles, helping customers reduce both water consumption and cleaning costs. Driven by a dedicated research team with expertise in materials, mechanical, and bio-inspired engineering, spotLESS Materials actively engages in collaborative projects to address various industry needs and enhance its product offerings. The company sells its products through online platforms, making its innovative solutions accessible to a wide audience.

VaxForm

Grant in 2019
VaxForm offers vaccine product consultation and contract development services. The company was founded in 2010 and is headquartered in Lehigh Valley, Pennsylvania.

OsciFlex

Grant in 2019
OsciFlex LLC, founded in 2017 and based in Philadelphia, Pennsylvania, specializes in developing a wearable medical device aimed at preventing blood clots in patients. The device functions by stimulating calf muscle contractions through a muscle stretch reflex, which promotes valve sinus recirculatory flow. This innovative approach helps to prevent venous thromboembolism (VTE), a serious condition that can lead to significant health complications. By offering an alternative to traditional anti-coagulation pharmaceuticals, which can be costly and carry risks, OsciFlex aims to enhance patient care and reduce healthcare costs associated with blood clot management.

Equilibria Leadership Consulting

Grant in 2018
Equilibria Leadership Consulting offers consulting, training, development programs, and coaching. The company was founded in 2007 and is headquartered in Philadelphia, Pennsylvania.

Behaivior

Grant in 2018
Behaivior LLC is a digital health company based in Pittsburgh, Pennsylvania, focused on predicting and preventing addiction relapses through innovative technology. Founded in 2017, Behaivior develops a platform that combines wearable devices and machine learning algorithms to monitor key physiological signals such as heart rate and motion. This system, known as Recovery, is designed to support mental health recovery and wellness by delivering timely interventions based on real-time data. By utilizing a software-as-a-service (SaaS) model, Behaivior empowers individuals to maintain their recovery process while enabling care providers to better assist their clients. The integration of AI and behavioral health technology allows Behaivior to recognize patterns in human behavior, ultimately aiming to enhance mental well-being and reduce the incidence of crises, including relapse.

Dynalene

Grant in 2018
Dynalene Inc. is a company based in Whitehall, Pennsylvania, specializing in the development, manufacturing, and distribution of industrial heat transfer fluids and coolants suitable for ultra-low temperature cryogenic applications. The product range includes glycols, brines, potassium formate, calcium chloride, and high-performance coolants, alongside nanodiamond products and functionalized nano-materials. These offerings cater to various industries, including fuel cells, solar and geothermal applications, HVAC, supermarket refrigeration, plastics manufacturing, and pharmaceuticals. Additionally, Dynalene provides lab services that encompass thermal and physical analysis, chemical testing, and material and corrosion testing. The company, founded in 1993, also sells its products through an online store, ensuring accessibility for its clients.

NeuroFlow

Grant in 2018
NeuroFlow, Inc. is a digital health company based in Philadelphia, Pennsylvania, that specializes in providing a platform for behavioral health and patient engagement throughout the mental healthcare continuum. Founded in 2016, NeuroFlow offers cloud-based tools designed for remote patient monitoring and the integration of behavioral health across various care settings, including psychology, primary care, and pain management. The platform empowers healthcare providers to track and engage patients through evidence-based practices, enhancing patient compliance and overall wellness. NeuroFlow's solutions cater to a diverse range of stakeholders, including practices, clinics, hospitals, health plans, and individuals. The company collaborates with several strategic partners, such as Smart Health Innovation Lab and Mental Health America, to further its mission of improving mental health outcomes.

Verix Health

Grant in 2017
Verix Health is focused on creating a range of steerable surgical devices designed for minimally invasive diagnosis and treatment of hard-to-reach lesions in the human body. Founded by Professor Mark Yim and PCI Ventures at the University of Pennsylvania, the company is incubated at the Pennovation Center in Philadelphia. Its innovative products aim to provide access and control for accurately targeting cancer in challenging anatomical locations, thereby allowing patients to receive effective treatments for tumors that are difficult to access through traditional surgical methods.

Amriton

Grant in 2017
Amriton is a water treatment technology company that provides treatment solutions to remove harmful pollutants from water. The company creates a technology that removes organic pollutants from water by using polymer-coated sand. Amriton was founded in 2014 and is headquartered in Philadelphia, PA.

LumiShield

Grant in 2017
LumiShield Technologies Inc. specializes in anti-corrosion products tailored for the metal plating industry. Founded in 2014 and headquartered in Pittsburgh, Pennsylvania, the company has introduced Lumidize®, an innovative aluminum oxide coating designed for the $11 billion metal pretreatment market. This coating enhances the adhesion of paints to various metal substrates, significantly improving corrosion resistance. LumiShield's products cater to diverse sectors, including biomedical, automotive, aerospace, infrastructure, electronics, manufacturing, marine, and consumer goods. By leveraging their proprietary chemistry, Lumidize® allows manufacturers to utilize existing capital equipment, streamlining production processes and reducing costs while addressing environmental concerns associated with traditional technologies.

BioSignal Analytics

Grant in 2016
BioSignal Analytics specializes in automated interpretation technology based on machine learning algorithms. The company's headquarters are in Philadelphia, Pennsylvania.

Instadiagnostics

Grant in 2016
Instadiagnostics Inc. develops a point-of-care (POC) diagnostic platform that aims to bring centralized laboratory testing directly to patients at their bedside. This innovative platform enables early diagnosis and treatment monitoring in various settings, including primary care centers, community clinics, and emergency departments. By eliminating the need for additional trips for blood tests and reducing lengthy wait times for results, Instadiagnostics enhances patient care and satisfaction. The company, incorporated in 2015 and based in Philadelphia, Pennsylvania, focuses on streamlining the diagnostic process, ultimately aiming to reduce the number of medical visits and overall healthcare costs.

Dynalene

Grant in 2016
Dynalene Inc. is a company based in Whitehall, Pennsylvania, specializing in the development, manufacturing, and distribution of industrial heat transfer fluids and coolants suitable for ultra-low temperature cryogenic applications. The product range includes glycols, brines, potassium formate, calcium chloride, and high-performance coolants, alongside nanodiamond products and functionalized nano-materials. These offerings cater to various industries, including fuel cells, solar and geothermal applications, HVAC, supermarket refrigeration, plastics manufacturing, and pharmaceuticals. Additionally, Dynalene provides lab services that encompass thermal and physical analysis, chemical testing, and material and corrosion testing. The company, founded in 1993, also sells its products through an online store, ensuring accessibility for its clients.

Syandus

Grant in 2016
Syandus Inc. is a company that specializes in intelligent simulation learning technology tailored for the pharmaceutical sector. Based in Exton, Pennsylvania, it offers a range of products, including the Virtual Conventions platform, which employs responsive technology to assist patients, and the Medical Scenario Simulator, designed for clinicians to practice clinical decision-making in a virtual setting. Syandus also provides a technology platform aimed at enhancing promotional experiential learning and multichannel marketing for pharmacies. This platform helps pharmacies boost sales, influence prescription behaviors, and connect more effectively with healthcare providers. Established in 2001, Syandus seeks to transform how healthcare professionals, students, and patients comprehend life science and medical concepts through innovative technology and engaging learning experiences.

PolyK Technologies

Grant in 2016
PolyK Technologies is a high-tech company that focuses on high-voltage dielectrics, piezoelectric materials, and smart materials, and test instruments and applications. PolyK is based in State College, Pennsylvania, which is home to Penn State University's dielectric and piezoelectric technology.

LumiShield

Grant in 2015
LumiShield Technologies Inc. specializes in anti-corrosion products tailored for the metal plating industry. Founded in 2014 and headquartered in Pittsburgh, Pennsylvania, the company has introduced Lumidize®, an innovative aluminum oxide coating designed for the $11 billion metal pretreatment market. This coating enhances the adhesion of paints to various metal substrates, significantly improving corrosion resistance. LumiShield's products cater to diverse sectors, including biomedical, automotive, aerospace, infrastructure, electronics, manufacturing, marine, and consumer goods. By leveraging their proprietary chemistry, Lumidize® allows manufacturers to utilize existing capital equipment, streamlining production processes and reducing costs while addressing environmental concerns associated with traditional technologies.

Ascent Bio-Nano Technologies

Grant in 2015
Ascent Bio-Nano Technologies, Inc. is engaged in the development and commercialization of miniature flow cytometry instruments and acoustofluidic chips for biomedical research, diagnostics, and therapeutic applications. Originating from research at Penn State University, the company's technology facilitates the rapid prototype development of devices that enable sample preparation, separation, and manipulation of bioparticles, including cells and vesicles. Based in State College, Pennsylvania, Ascent Bio-Nano Technologies focuses on providing low-cost solutions for biological studies and medical diagnostics, while also partnering with industry stakeholders for customized product development and integration.

Amriton

Grant in 2015
Amriton is a water treatment technology company that provides treatment solutions to remove harmful pollutants from water. The company creates a technology that removes organic pollutants from water by using polymer-coated sand. Amriton was founded in 2014 and is headquartered in Philadelphia, PA.

Longevity Biotech

Grant in 2015
Longevity Biotech, Inc. is a biopharmaceutical company focused on developing innovative therapeutic drug candidates using its proprietary Hybridtide peptide technology. This platform enables the creation of customizable peptides that offer improved stability and absorption, enhancing treatment options for various medical conditions. The company's pipeline includes LBT-3627, a neuroprotective agent aimed at treating disorders such as Parkinson's disease; LBT-6030, a dual agonist targeting glucagon for metabolic conditions; and LBT-5001, a fusion inhibitor. Additionally, Longevity Biotech is conducting clinical studies to identify specific immune and inflammatory markers for the diagnosis of Parkinson's disease. Founded in 2010 and based in Philadelphia, Pennsylvania, Longevity Biotech is committed to advancing drug discovery and development in the biopharmaceutical sector.

PolyK Technologies

Grant in 2015
PolyK Technologies is a high-tech company that focuses on high-voltage dielectrics, piezoelectric materials, and smart materials, and test instruments and applications. PolyK is based in State College, Pennsylvania, which is home to Penn State University's dielectric and piezoelectric technology.

ATRP Solutions

Grant in 2014
ATRP SOLUTIONS develops and manufactures specialty polymers that meet their needs. It recognizes the polymeric materials for improving the performance of commercial products in the areas of personal care and cosmetics, detergents and surfactants, paints, pigments, coatings, and biocompatible materials. It was founded in 2006 and is headquartered in Pittsburgh, Pennsylvania.

Impulse Technology

Grant in 2014
Impulse Technology LLC focuses on nanofabrication, MEMS design, and ultra-thin film characterization, offering specialized fabrication of nanoscale patterned thin film specimens. The company conducts mechanical, thermal, electrical, and optical characterization of materials at the micro-nano scales. Its product portfolio includes nanoscale patterned thin film specimens for applications such as micro-electrodes and heaters, as well as innovative technologies for thermoelectric energy conversion. Additionally, Impulse Technology develops therapeutic devices, including below-the-knee prosthetic leg components that aim to replicate natural leg functions, thereby enhancing mobility and quality of life for amputees. Founded in 2013 and based in State College, Pennsylvania, Impulse Technology serves both academic and industry researchers.

Citrine Informatics

Grant in 2014
Citrine Informatics, Inc. is a technology company that specializes in artificial intelligence and machine learning to enhance materials development. Founded in 2013 and headquartered in Redwood City, California, with an additional office in Pittsburgh, the company operates a platform that aggregates and analyzes extensive datasets related to materials, chemicals, and devices. This platform aims to streamline research and development, manufacturing, and supply chain processes for organizations involved in producing physical products. By employing data science and machine learning, Citrine Informatics accelerates the discovery of new materials and helps identify defects early in the research process, thereby improving product design and development efficiency across various sectors, including energy, aerospace, and electronics.

ActuatedMedical

Grant in 2014
Actuated Medical, Inc. engages in outsourced research and development, designing and modeling, prototyping, and manufacturing medical devices. It offers occlusion clearing systems, such as NG-Clear for removing and disintegrating nasogastric (NG) tube clogs; and PEG-Clear for clearing and breaking up percutaneous endoscopic gastrostomy (PEG) tube clogs. The company also provides controlled tissue penetration systems, including resonance assisted insertion lancets for humane blood sampling of research subjects; low insertion force epidural systems for the entry of epidural needles; and resonance assisted vascular entry needles for aiding in vascular access for compromised and difficult access patients. In addition, Actuated Medical, Inc. offers magnetic resonance imaging compatible systems, such as direct drive motor for improving patient care by enabling various diagnostic and surgical procedures to be performed during MRI imaging; and transdermal patches for administering long-term and controlled-delivery medications subcutaneously. The company was formerly known as Piezo Resonance Innovations, Inc. and changed its name to Actuated Medical, Inc. in September 2011. Actuated Medical, Inc. was founded in 2006 and is based in Bellefonte, Pennsylvania.

PolyK Technologies

Grant in 2013
PolyK Technologies is a high-tech company that focuses on high-voltage dielectrics, piezoelectric materials, and smart materials, and test instruments and applications. PolyK is based in State College, Pennsylvania, which is home to Penn State University's dielectric and piezoelectric technology.

Longevity Biotech

Grant in 2013
Longevity Biotech, Inc. is a biopharmaceutical company focused on developing innovative therapeutic drug candidates using its proprietary Hybridtide peptide technology. This platform enables the creation of customizable peptides that offer improved stability and absorption, enhancing treatment options for various medical conditions. The company's pipeline includes LBT-3627, a neuroprotective agent aimed at treating disorders such as Parkinson's disease; LBT-6030, a dual agonist targeting glucagon for metabolic conditions; and LBT-5001, a fusion inhibitor. Additionally, Longevity Biotech is conducting clinical studies to identify specific immune and inflammatory markers for the diagnosis of Parkinson's disease. Founded in 2010 and based in Philadelphia, Pennsylvania, Longevity Biotech is committed to advancing drug discovery and development in the biopharmaceutical sector.

Moai technologies

Grant in 2013
Moai Technologies Inc. specializes in integrated supply-chain management tools and services tailored for global commerce. The company's offerings encompass a wide range of solutions including logistics, sourcing, procurement, spend management, and contract management, along with e-sourcing consulting and technology-enabled services. Its RapidSource program delivers strategic sourcing analysis for specific commodities, while the CompleteSource Solution Suite facilitates the implementation of e-sourcing strategies through various online negotiation formats such as reverse auctions and multi-stage negotiations. Moai also provides comprehensive consulting services that cover custom commodity templates development, cost modeling, and performance tuning. Additionally, the company offers business process outsourcing (BPO) solutions and hosted services, catering to the needs of both enterprises and mid-sized companies across industries such as airline, food, gas, and water. Founded in 1996 and headquartered in Pittsburgh, Pennsylvania, Moai Technologies aims to enhance supply chain efficiency and cost-effectiveness for its clients.

CEINT

Grant in 2013
The Center for the Environmental Implications of NanoTechnology (CEINT) is exploring the relationship between a vast array of nanomaterials— from natural, to manufactured, to those produced incidentally by human activities— and their potential environmental exposure, biological effects, and ecological impacts. Headquartered at Duke University, CEINT is a collaborative effort bringing together researchers from Duke, Carnegie Mellon University, Howard University, Virginia Tech, University of Kentucky, and Stanford University. CEINT academic collaborations include on-going activities coordinated with faculty at Baylor, Clemson, North Carolina State, and North Carolina Central universities, with researchers at NIST and EPA government labs, and with key international partners.

Ascent Bio-Nano Technologies

Grant in 2013
Ascent Bio-Nano Technologies, Inc. is engaged in the development and commercialization of miniature flow cytometry instruments and acoustofluidic chips for biomedical research, diagnostics, and therapeutic applications. Originating from research at Penn State University, the company's technology facilitates the rapid prototype development of devices that enable sample preparation, separation, and manipulation of bioparticles, including cells and vesicles. Based in State College, Pennsylvania, Ascent Bio-Nano Technologies focuses on providing low-cost solutions for biological studies and medical diagnostics, while also partnering with industry stakeholders for customized product development and integration.

University of Pittsburgh

Grant in 2013
The University of Pittsburgh, established in 1787 as the Pittsburgh Academy, is a prominent state-related research university recognized for its academic excellence and research capabilities. It is a member of the Association of American Universities, which includes 62 leading doctorate-granting institutions in North America. The university ranks 24th globally and is recognized as one of the top public universities in the United States, holding the top position in Pennsylvania. The University of Pittsburgh is noted for its strong research productivity and impact, as evidenced by its high ranking in the Performance Rankings of Scientific Papers for World Universities. The university's Pittsburgh School of Medicine, founded in 1886, provides professional medical education, including a Doctor of Medicine (MD) degree. Pitt's students have received numerous prestigious awards, including four Rhodes Scholarships between 2006 and 2012, making it one of the few public institutions to achieve such recognition.

Love Park Robotics

Grant in 2013
Love Park Robotics is a Philadelphia-based start-up focused on developing advanced technologies for intelligent products and services. The company's flagship platform, CoPilot, offers sliding-scale autonomous navigation for service vehicles in both indoor and dynamic outdoor environments. Additionally, Love Park Robotics specializes in 3D perception software that enhances industrial robotic applications. This software supports advanced driver assistance systems, allowing service vehicles to navigate autonomously and addressing accessibility challenges for wheelchair users. By providing flexible licensing options and custom solutions, the company collaborates with original equipment manufacturers (OEMs) to integrate its technology into innovative products and services, facilitating the creation of robotics systems that utilize artificial intelligence to interact effectively with the physical world.

ActuatedMedical

Grant in 2012
Actuated Medical, Inc. engages in outsourced research and development, designing and modeling, prototyping, and manufacturing medical devices. It offers occlusion clearing systems, such as NG-Clear for removing and disintegrating nasogastric (NG) tube clogs; and PEG-Clear for clearing and breaking up percutaneous endoscopic gastrostomy (PEG) tube clogs. The company also provides controlled tissue penetration systems, including resonance assisted insertion lancets for humane blood sampling of research subjects; low insertion force epidural systems for the entry of epidural needles; and resonance assisted vascular entry needles for aiding in vascular access for compromised and difficult access patients. In addition, Actuated Medical, Inc. offers magnetic resonance imaging compatible systems, such as direct drive motor for improving patient care by enabling various diagnostic and surgical procedures to be performed during MRI imaging; and transdermal patches for administering long-term and controlled-delivery medications subcutaneously. The company was formerly known as Piezo Resonance Innovations, Inc. and changed its name to Actuated Medical, Inc. in September 2011. Actuated Medical, Inc. was founded in 2006 and is based in Bellefonte, Pennsylvania.

ATRP Solutions

Grant in 2012
ATRP SOLUTIONS develops and manufactures specialty polymers that meet their needs. It recognizes the polymeric materials for improving the performance of commercial products in the areas of personal care and cosmetics, detergents and surfactants, paints, pigments, coatings, and biocompatible materials. It was founded in 2006 and is headquartered in Pittsburgh, Pennsylvania.

nanoGriptech

Grant in 2012
nanoGriptech, Inc. specializes in manufacturing micro-fibrillar polymer-based dry adhesives and surfaces, drawing inspiration from the natural adhesion mechanism of gecko feet. Founded in 2012 and headquartered in Pittsburgh, Pennsylvania, the company offers a range of products, including the Setex Gecko Tape, which is a repeatable, residue-free, non-tacky tape, and the Setex Ultra-Thin Fastener, designed for seamless integration with smooth surfaces. Its innovative adhesive solutions are tailored for diverse applications such as wearables, sports gear, semiconductors, robotics, medical devices, automotive components, and packaging. nanoGriptech aims to provide a superior alternative to traditional reusable adhesives, focusing on durability and customization. The company has established partnerships with multinational corporations and has recently begun small volume sales in the high-friction clothing market.

ActuatedMedical

Grant in 2012
Actuated Medical, Inc. engages in outsourced research and development, designing and modeling, prototyping, and manufacturing medical devices. It offers occlusion clearing systems, such as NG-Clear for removing and disintegrating nasogastric (NG) tube clogs; and PEG-Clear for clearing and breaking up percutaneous endoscopic gastrostomy (PEG) tube clogs. The company also provides controlled tissue penetration systems, including resonance assisted insertion lancets for humane blood sampling of research subjects; low insertion force epidural systems for the entry of epidural needles; and resonance assisted vascular entry needles for aiding in vascular access for compromised and difficult access patients. In addition, Actuated Medical, Inc. offers magnetic resonance imaging compatible systems, such as direct drive motor for improving patient care by enabling various diagnostic and surgical procedures to be performed during MRI imaging; and transdermal patches for administering long-term and controlled-delivery medications subcutaneously. The company was formerly known as Piezo Resonance Innovations, Inc. and changed its name to Actuated Medical, Inc. in September 2011. Actuated Medical, Inc. was founded in 2006 and is based in Bellefonte, Pennsylvania.
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