National Science Foundation

The National Science Foundation is an independent federal agency in the United States that funds and supports research and education in science and engineering. It funds fundamental research and education across all fields of science and engineering and administers non-dilutive funding programs to aid early‑stage technology development, helping translate discoveries into commercially viable products and services. Through grants and fellowships, the NSF supports researchers, educators, and startups, contributing to innovation and U.S. competitiveness. The agency operates with a substantial budget to advance science, engineering, and STEM education nationwide.

James Donlon

Program Director

Sean L. Jones

Assistant Director for Mathematical and Physical Sciences

Debasis Majumdar

Program Director

Graciela Narcho

Staff Associate

Sethuraman Panchanathan

Director

Past deals in North Carolina

Harpe Bio

Grant in 2023
Harpe Bioherbicide Solutions is a Raleigh-based company that provides sustainable weed-management solutions for organic and industrial agriculture. Harpe Bio's technologies deliver natural crop protection by utilizing a variety of plant extracts. The plant extracts serve as a platform that may be tailored to various weed management circumstances. Harpe's herbicide platform can be used alone or in conjunction with any currently marketed herbicide. Harpe's new modes and areas of action will improve synthetic herbicide efficacy, including the reduction of resistant weed populations.

University of North Carolina at Wilmington

Grant in 2023
The University of North Carolina Wilmington, the state's coastal university, is dedicated to the integration of teaching and mentoring with research and service. University of North Carolina Wilmington, commitment to student engagement, creative inquiry, critical thinking, thoughtful expression and responsible citizenship is expressed in our baccalaureate and master's programs, as well as doctoral programs in areas of expertise that serve state needs. Our culture reflects our values of diversity and globalization, ethics and integrity, and excellence and innovation.

North Carolina Agricultural and Technical State University

Grant in 2022
North Carolina A&T State University is so many things to so many people, both in our state and around the country. North Carolina A&T State University is an HBCU. We are a top-flight research university, the largest historically black university (HBCU) in the country, the #1 producer of degrees awarded to African Americans in North Carolina and nationally recognized or our excellence in science, technology, mathematics and engineering (STEM) education. We are a diverse community, bound by intense pride and tradition, with fiercely loyal alumni who hold positions of importance and influence in companies and government agencies across the state, the country and the world. We are achievers, driven by a curious, limitless, fearless spirit that fuels discovery and innovation, resulting in 41 patents issued based on our research, as well as numerous spin-off and start-up companies. We are inclusive and welcoming, with students from many backgrounds and cultures, every part of our state, our nation and countries around the globe. We are passionate, driven by a desire to do more, be more and make more of a difference. Since we opened our doors in 1892, we have focused on giving every student the hands-on opportunities, core knowledge and global perspective that will lead them to make real and lasting change in their lives and the lives of others. At N.C. A&T, we have so much to be proud of, and you can learn more about those "Points of Pride" here. You can also use the links below to learn more about what makes N.C. A&T unique, from our leadership and history to our many rankings and recognitions.

University of North Carolina at Greensboro

Grant in 2022
The University of North Carolina at Greensboro, also known as UNCG and UNC Greensboro, is a public coeducational and research university in Greensboro in North Carolina in the United States of America, and it is a constituent institution of the system of the University of North Carolina. However, the University of North Carolina at Greensboro is a stand-alone university and awards its own degrees like all members of the system of the University of North Carolina . The Southern Association of Colleges and Schools Commission on Colleges accredits the University of North Carolina at Greensboro to award baccalaureate, masters, specialist, and doctoral degrees.

Ecoclosure

Grant in 2022
Ecoclosure, founded in 2019 and based in Charlotte, North Carolina, specializes in regenerable building enclosures suitable for commercial, industrial, and residential applications. The company focuses on developing technology that enhances indoor air quality while reducing energy consumption in buildings. Its innovative designs incorporate monitoring and automation features tailored to various building programs, climate zones, and orientations. By implementing these regenerable enclosures, Ecoclosure aims to create healthier indoor environments that prioritize occupant well-being and ensure revitalized air quality.

ColoWrap

Grant in 2021
ColoWrap, LLC is a medical device company based in Durham, North Carolina, established in 2012. The company specializes in developing a non-invasive device designed to enhance the efficiency and comfort of colonoscopy procedures. ColoWrap's innovative device exerts sustained, adjustable pressure on the patient's lower abdomen, effectively preventing looping in the colon. This minimizes the need for manual pressure and reduces the necessity for patient repositioning during the procedure. Constructed from latex-free material similar to that used in high-performance wetsuits, the device aims to facilitate a more comfortable and less invasive experience for patients while allowing medical practitioners to perform colonoscopies more effectively.

Minerva Lithium

Grant in 2021
Minerva Lithium, founded in 2020 in Greensboro, North Carolina, focuses on advancing critical mineral extraction technologies. The company has developed a proprietary nano mosaic membrane filter system that enhances the extraction of lithium from non-traditional water resources. This innovative approach aims to improve lithium recovery rates and support the clean energy sector, as well as the automotive and technology industries, by providing high-grade pure minerals essential for various applications. In addition to boosting lithium availability, Minerva's methods also facilitate the recovery of usable water, contributing to sustainable practices in mineral extraction.

North Carolina Central University

Grant in 2021
North Carolina Central University, founded in 1910 in Durham, North Carolina, is a historically black university that offers more than 100 undergraduate and graduate programs across nearly 30 academic departments. It is known for distinctive degrees such as a master’s in Jazz Studies and a bachelor’s in Apparel Design, as well as joint graduate programs that combine law, business, library science, and information science. The university provides a range of financial aid options, including need‑based government assistance and institutional scholarships, and encourages applications from students of all races and ethnicities. With a focus on academic excellence, research, and cultural awareness, the institution maintains a diverse student body and a commitment to inclusive education.

Kaleido

Grant in 2021
Kaleido, Inc. is a developer of a cloud-based blockchain platform that simplifies the creation and management of enterprise private blockchain networks. Founded in 2005 and based in Raleigh, North Carolina, the company provides a versatile platform that supports multiple blockchain protocols, including Ethereum, Polygon Edge, and Hyperledger Fabric. Kaleido's services encompass features such as token transfer, token swap, document storage, and identity management, ensuring compliance and scalability for enterprises in regulated industries. The platform is designed for high availability and disaster recovery, boasting a 99.99% uptime over the past four years. With its focus on simplifying the adoption of blockchain and digital asset technologies, Kaleido serves a diverse array of sectors, including finance, healthcare, and supply chain management, helping organizations accelerate their digital transformation efforts.

Gradient Medical

Grant in 2021
Gradient Medical develops innovative interventional oncology services focused on bringing Ablative Cancer Electroporation (ACE) therapy to clinical settings. Established in 2020, the company is based in Raleigh, North Carolina.

Novo Aero Technology

Grant in 2021
Founded in 2018, Novo Aero Technology specializes in developing Vertical Take-off and Landing (VTOL) aircraft. Its innovative technology features compact propellers positioned centrally within the aircraft fuselage, reducing moving parts and enhancing efficiency.

BioAesthetics

Grant in 2021
BioAesthetics develops tissue-engineered nipple-areolar complex grafts to support breast reconstruction after mastectomy. The graft is designed as a scaffold for the patient's own cells to populate and regenerate the nipple and areola during reconstruction, aiming to improve cosmetic and reconstructive outcomes. The company originated as a Tulane University spin-out and was founded in 2015.

Minerva Lithium

Pre Seed Round in 2021
Minerva Lithium, founded in 2020 in Greensboro, North Carolina, focuses on advancing critical mineral extraction technologies. The company has developed a proprietary nano mosaic membrane filter system that enhances the extraction of lithium from non-traditional water resources. This innovative approach aims to improve lithium recovery rates and support the clean energy sector, as well as the automotive and technology industries, by providing high-grade pure minerals essential for various applications. In addition to boosting lithium availability, Minerva's methods also facilitate the recovery of usable water, contributing to sustainable practices in mineral extraction.

Inanovate

Grant in 2020
Inanovate Inc. is a biotechnology company that specializes in the development of protein screening and analysis technologies for the life sciences industry. Founded in 2006 and headquartered in Sioux Falls, South Dakota, with an additional office in Raleigh, North Carolina, Inanovate offers its flagship product, Bio-ID, a protein screening biochip platform. This platform provides sensitive real-time kinetic data for multiple protein interactions, facilitating applications in protein research, drug development, quality control, biomarker profiling, and clinical diagnostics. The company also offers a range of services, including biomarker discovery and validation programs, nano-particle surface technology for protein immobilization, and various protein micro-array services. Inanovate serves a diverse clientele, including researchers, clinical centers, and biotech and pharmaceutical companies, with operations extending to the United States and the United Kingdom.

Lumedica

Grant in 2020
Lumedica develops affordable Optical Coherence Tomography (OCT) imaging technologies for medical applications. Its devices use optical components to capture detailed images from tissue micro-layers, enabling early detection of eye diseases at a lower cost.

BENANOVA

Grant in 2020
BENANOVA develops safer antimicrobial products and eco-friendly materials for disinfectant, cosmetic, agricultural, and textile applications. Its Environmentally-benign Nanoparticles provide high efficacy with a degradable design, offering environmentally friendly replacements for silver nanoparticle antimicrobials and the potential to reduce chemical use in crop protection by up to 90%. The company also uses lignin-based, biodegradable materials from bio-renewable sources to support sustainable agriculture and specialty textiles, combining strong performance with reduced environmental impact.

MuukTest

Grant in 2020
MuukTest is a software testing platform powered by artificial intelligence that enhances software testing productivity and quality assurance for development teams, with claims of substantial efficiency gains. Founded in 2019 and based in Raleigh, North Carolina, the company combines AI-powered software with expert QA services and integrates into existing CI/CD workflows. Its platform offers features such as self-healing tests and detailed bug reports, enabling comprehensive test coverage and streamlined testing within established development pipelines.

RENCI

Grant in 2020
RENCI develops and deploys advanced technologies to enable research discoveries and practical innovations. RENCI collaborates with researchers, government, and industry to engage and solve problems affecting North Carolina, the United States, and the world. RENCI is a critical catalyst for data-driven discoveries that lead to improved health, a safer environment, and increased economic and business success.

Ecoclosure

Grant in 2020
Ecoclosure, founded in 2019 and based in Charlotte, North Carolina, specializes in regenerable building enclosures suitable for commercial, industrial, and residential applications. The company focuses on developing technology that enhances indoor air quality while reducing energy consumption in buildings. Its innovative designs incorporate monitoring and automation features tailored to various building programs, climate zones, and orientations. By implementing these regenerable enclosures, Ecoclosure aims to create healthier indoor environments that prioritize occupant well-being and ensure revitalized air quality.

Third Floor Materials

Grant in 2020
Third Floor Materials develops algorithmic technology to support infrared spectroscopy and the design of optical components for specialized IR applications. The company provides coating services on a wide range of substrate materials and shapes, using deposition methods such as magnetron sputtering, plasma-assisted molecular beam epitaxy, pulsed laser deposition, resistive and e-beam evaporation, metal-organic vapor phase epitaxy, and chemical deposition. Its technology enables photonic design, concept development, and feasibility studies for infrared systems. Founded in 2016, the company is headquartered in Raleigh, North Carolina.

Kampanics

Grant in 2020
Kampanics is a research and development company based in Oak Ridge, North Carolina, specializing in microacoustic devices and piezomems technology. Founded by Kushal Bhattacharjee, the company focuses on providing innovative solutions in signal processing, sensing, and energy harvesting. By collaborating with academic associates, corporate partners, and domain experts, Kampanics aims to facilitate the development of new products and services that leverage its specialized technological expertise.

Microgrid Labs

Grant in 2020
Microgrid Labs is a software and consulting company specializing in microgrids, commercial fleet electrification, and energy storage. It provides software and consulting services for the design, deployment, and operation of microgrids and related energy systems, including electric vehicle infrastructure and solar forecasting. The company offers initial assessment, feasibility studies, modeling, simulation, and optimization to support fleet operators and energy project planners, enabling reliable operations, optimized charging, and cost-effective energy management.

BENANOVA

Grant in 2020
BENANOVA develops safer antimicrobial products and eco-friendly materials for disinfectant, cosmetic, agricultural, and textile applications. Its Environmentally-benign Nanoparticles provide high efficacy with a degradable design, offering environmentally friendly replacements for silver nanoparticle antimicrobials and the potential to reduce chemical use in crop protection by up to 90%. The company also uses lignin-based, biodegradable materials from bio-renewable sources to support sustainable agriculture and specialty textiles, combining strong performance with reduced environmental impact.

VitalFlo

Grant in 2019
VitalFlo is a digital health company that manufactures spirometers, handheld medical devices enabling asthmatic patients to track their lung health and asthma medications. It also develops software connecting patients with chronic respiratory diseases to their physicians, aiming to keep patients out of the ER by remotely monitoring lung function and air quality triggers.

North Carolina Agricultural and Technical State University

Grant in 2019
North Carolina A&T State University is so many things to so many people, both in our state and around the country. North Carolina A&T State University is an HBCU. We are a top-flight research university, the largest historically black university (HBCU) in the country, the #1 producer of degrees awarded to African Americans in North Carolina and nationally recognized or our excellence in science, technology, mathematics and engineering (STEM) education. We are a diverse community, bound by intense pride and tradition, with fiercely loyal alumni who hold positions of importance and influence in companies and government agencies across the state, the country and the world. We are achievers, driven by a curious, limitless, fearless spirit that fuels discovery and innovation, resulting in 41 patents issued based on our research, as well as numerous spin-off and start-up companies. We are inclusive and welcoming, with students from many backgrounds and cultures, every part of our state, our nation and countries around the globe. We are passionate, driven by a desire to do more, be more and make more of a difference. Since we opened our doors in 1892, we have focused on giving every student the hands-on opportunities, core knowledge and global perspective that will lead them to make real and lasting change in their lives and the lives of others. At N.C. A&T, we have so much to be proud of, and you can learn more about those "Points of Pride" here. You can also use the links below to learn more about what makes N.C. A&T unique, from our leadership and history to our many rankings and recognitions.

University of North Carolina at Greensboro

Grant in 2019
The University of North Carolina at Greensboro, also known as UNCG and UNC Greensboro, is a public coeducational and research university in Greensboro in North Carolina in the United States of America, and it is a constituent institution of the system of the University of North Carolina. However, the University of North Carolina at Greensboro is a stand-alone university and awards its own degrees like all members of the system of the University of North Carolina . The Southern Association of Colleges and Schools Commission on Colleges accredits the University of North Carolina at Greensboro to award baccalaureate, masters, specialist, and doctoral degrees.

3i Nanotech

Grant in 2019
Founded in 2018, 3i Nanotech develops point-of-care platform technology designed to track protein biomarkers in human samples. Its proprietary system enables early detection of cardiac biomarkers and infectious diseases, facilitating prehospital testing for medical professionals.

Telli Technologies

Grant in 2019
Telli Technologies develops sensors for SiC and GaN power electronics. The company was founded in 2016 and is headquartered in Charlotte, North Carolina.

Allumia

Grant in 2019
Founded in 2013, Allumia specializes in lighting upgrades for commercial facilities. It offers design, funding, installation, and maintenance services, serving markets such as office spaces, retail stores, and industrial plants. The company uses a software and IoT platform to optimize energy efficiency, enabling clients to reduce costs and increase savings.

Genoverde Biosciences

Grant in 2018
Founded in 2015 and based in Raleigh, North Carolina, Genoverde Biosciences specializes in developing cell wall technology to enhance lignocellulosic energy crops. Its innovative approach aims to increase biomass yield by improving the secondary cell wall thickness of dedicated bioenergy crops, facilitating the production of liquid fuels from plant sugars.

Lumedica

Grant in 2018
Lumedica develops affordable Optical Coherence Tomography (OCT) imaging technologies for medical applications. Its devices use optical components to capture detailed images from tissue micro-layers, enabling early detection of eye diseases at a lower cost.

Appia

Grant in 2018
Appia is a prominent mobile user acquisition network that specializes in delivering mobile app downloads to over 1 billion users across 200 countries. The company provides a marketplace platform for mobile application developers, offering them a distribution point while enabling advertisers to acquire high-value customers. Appia's advanced technology and extensive network ensure that applications reach a large and engaged audience, maximizing app installs and profit per install for its clients. With a diverse portfolio of trusted brands, Appia has established itself as a leader in mobile app discovery. The company operates from offices in San Francisco, California, and Durham, North Carolina, along with global sales offices, and has gained recognition for its rapid growth and innovation in the mobile advertising space.

High Road Learning

Grant in 2018
High Road Learning promotes a dual-language approach to personalizing English-language learners' literacy growth. The company is based in Raleigh, North Carolina.

BENANOVA

Grant in 2018
BENANOVA develops safer antimicrobial products and eco-friendly materials for disinfectant, cosmetic, agricultural, and textile applications. Its Environmentally-benign Nanoparticles provide high efficacy with a degradable design, offering environmentally friendly replacements for silver nanoparticle antimicrobials and the potential to reduce chemical use in crop protection by up to 90%. The company also uses lignin-based, biodegradable materials from bio-renewable sources to support sustainable agriculture and specialty textiles, combining strong performance with reduced environmental impact.

Microgrid Labs

Grant in 2018
Microgrid Labs is a software and consulting company specializing in microgrids, commercial fleet electrification, and energy storage. It provides software and consulting services for the design, deployment, and operation of microgrids and related energy systems, including electric vehicle infrastructure and solar forecasting. The company offers initial assessment, feasibility studies, modeling, simulation, and optimization to support fleet operators and energy project planners, enabling reliable operations, optimized charging, and cost-effective energy management.

VitalFlo

Grant in 2018
VitalFlo is a digital health company that manufactures spirometers, handheld medical devices enabling asthmatic patients to track their lung health and asthma medications. It also develops software connecting patients with chronic respiratory diseases to their physicians, aiming to keep patients out of the ER by remotely monitoring lung function and air quality triggers.

Techverse

Grant in 2017
Techverse, Inc., established in 1997 and based in Cary, North Carolina, is a research and development firm specializing in advanced energy generation and utilization concepts. The company offers consulting services, including process development, experimental studies, and model simulations, to enhance energy efficiency for both government and industrial clients. Techverse utilizes specialized membrane separation processes and conducts laboratory, pilot, and full-scale experimental studies to improve process and energy efficiency. The company, founded by Dr. Ashok Damle, operates on a flexible basis, renting laboratory and office space as needed, and has successfully secured government funding through programs like SBIR while also generating revenue through consulting services and industrial contracts.

MAA Laboratories

Grant in 2017
MAA Laboratories, Inc. is a pharmaceutical company based in North Carolina, founded in 2013. The company specializes in developing advanced nano drug delivery systems and continuous manufacturing technologies, focusing on small water-soluble drug molecules. MAA Laboratories aims to address various drug delivery and solubility challenges through its innovative nanomedicine platform. The company also develops oral nanomedicines targeting conditions such as Alzheimer's and migraines, providing solutions for a range of therapeutic needs.

Redbud Labs

Grant in 2017
Founded in 2010, Redbud Labs specializes in developing and manufacturing Micro-Electro-Mechanical Systems (MEMS) and microfluidics technologies for the life science industry. The company offers actuated surface-attached posts films for fluid manipulation and microfluidic technologies for biosensing, enabling small-volume sample collection, processing, and analysis.

Microgrid Labs

Grant in 2016
Microgrid Labs is a software and consulting company specializing in microgrids, commercial fleet electrification, and energy storage. It provides software and consulting services for the design, deployment, and operation of microgrids and related energy systems, including electric vehicle infrastructure and solar forecasting. The company offers initial assessment, feasibility studies, modeling, simulation, and optimization to support fleet operators and energy project planners, enabling reliable operations, optimized charging, and cost-effective energy management.

Metalytics

Grant in 2016
Metalytics is a biotechnology company based in Morrisville, NC, founded in 2016. The firm specializes in cell factory analysis, offering technology-enabled services designed to assist cell engineers in the biotechnology and pharmaceutical sectors. Its flagship product, CoreMFATM, facilitates optimal cell line selection and identifies the best conditions for cell line production. Metalytics' services enable the mapping of metabolism within industrial cell factories, allowing for the determination of metabolic rates in living cells, which is otherwise difficult to measure. This capability aids synthetic biology and pharmaceutical companies in enhancing their production processes and addressing complex production challenges, ultimately contributing to a deeper understanding of metabolic pathways.

BTI Targetry

Grant in 2016
BTI Targetry specializes in the development and deployment of high-performance targets for radionuclide production. The company was founded in 2002 and is headquartered in Cary, North Carolina.

Roundtable Analytics

Grant in 2016
Roundtable Analytics, Inc. specializes in developing predictive analytics software solutions tailored for the healthcare sector. The company’s flagship product, OptimizED, is an emergency department insights platform that integrates historical and real-time data to enhance performance tracking and improvement efforts. By utilizing advanced predictive analytics and simulation modeling, Roundtable Analytics aims to streamline patient flow, minimize variability in practices, optimize resource utilization, and uncover new revenue opportunities. Founded in 2013 and headquartered in Durham, North Carolina, Roundtable Analytics combines expertise from mathematics, statistics, computer science, and operations research with insights from healthcare professionals to address significant challenges in the industry.

Genoverde Biosciences

Grant in 2016
Founded in 2015 and based in Raleigh, North Carolina, Genoverde Biosciences specializes in developing cell wall technology to enhance lignocellulosic energy crops. Its innovative approach aims to increase biomass yield by improving the secondary cell wall thickness of dedicated bioenergy crops, facilitating the production of liquid fuels from plant sugars.

Alievio

Grant in 2016
Alievio, Inc. is a North Carolina-based company that specializes in the design, development, and manufacturing of innovative ophthalmic medical devices for glaucoma patients. The company has introduced a novel device, Sollevio, which offers a noninvasive method for titrating postoperative intraocular pressure in the treatment of refractory glaucoma. This device serves as a significant advancement in glaucoma therapy, aiming to address the complications associated with traditional glaucoma surgeries while providing ophthalmologists with a valuable tool to halt the progression of the disease. Founded in 2010 and originally known as Camras Vision, Inc., Alievio changed its name in June 2019 and operates from Research Triangle Park, North Carolina.

Akoustis Technologies

Grant in 2016
Akoustis Technologies, Inc. is a high-tech semiconductor company based in Huntersville, North Carolina, that specializes in the development, design, manufacturing, and sale of radio frequency (RF) filter products for the mobile wireless device industry. Established in 2013, the company operates through two main segments: Foundry Fabrication Services and RF Filters. The Foundry Fabrication Services segment offers engineering review and semiconductor wafer-manufacturing services, while the RF Filters segment focuses on producing innovative amplifier and filter products for various applications, including smartphones, tablets, cellular infrastructure, Wi-Fi equipment, and military uses. Akoustis utilizes a proprietary microelectromechanical systems-based technology known as XBAW to create its filters, enabling efficient production and unique performance characteristics. The company generates revenue primarily through individual customer purchase orders.

Redbud Labs

Grant in 2015
Founded in 2010, Redbud Labs specializes in developing and manufacturing Micro-Electro-Mechanical Systems (MEMS) and microfluidics technologies for the life science industry. The company offers actuated surface-attached posts films for fluid manipulation and microfluidic technologies for biosensing, enabling small-volume sample collection, processing, and analysis.

SonoVol

Grant in 2015
SonoVol, Inc. is a company that develops and manufactures advanced ultrasound imaging systems tailored for the biotechnology and pharmaceutical sectors. Founded in 2012 and based in Durham, North Carolina, SonoVol offers a fully automated benchtop ultrasound platform known as Vega, which utilizes acoustic angiography technology. This imaging system streamlines preclinical screening processes by enabling researchers to quickly assess tumor size, location, morphology, and vascular density. The platform features a robotic multiplexed workflow that ensures hands-free data acquisition, enhancing throughput and standardization in studies regardless of the operator. SonoVol's technology aims to lower barriers for biologists in academic, government, and industry settings, ultimately facilitating more effective detection and treatment of tumors.

BTI Targetry

Grant in 2015
BTI Targetry specializes in the development and deployment of high-performance targets for radionuclide production. The company was founded in 2002 and is headquartered in Cary, North Carolina.

Edison Agrosciences

Grant in 2015
Edison Agrosciences, Inc. is an agricultural biotechnology company based in Durham, North Carolina, established in 2013. It specializes in developing innovative biotechnological solutions for the production of plant-based industrial materials, particularly focusing on alternative rubber crops. The company employs advanced computational breeding and agronomic techniques to enhance rubber concentration in underutilized plant parts, thereby improving per-acre yields. Edison Agrosciences aims to provide sustainable natural rubber sourced from alternative sunflower crops, catering to consumer, medical, and industrial markets. With a growing intellectual property portfolio and a commitment to forming strategic partnerships, the company seeks to mitigate risks associated with pilot-scale crop and product validation while driving advancements in sustainable biomaterials.

Roundtable Analytics

Grant in 2014
Roundtable Analytics, Inc. specializes in developing predictive analytics software solutions tailored for the healthcare sector. The company’s flagship product, OptimizED, is an emergency department insights platform that integrates historical and real-time data to enhance performance tracking and improvement efforts. By utilizing advanced predictive analytics and simulation modeling, Roundtable Analytics aims to streamline patient flow, minimize variability in practices, optimize resource utilization, and uncover new revenue opportunities. Founded in 2013 and headquartered in Durham, North Carolina, Roundtable Analytics combines expertise from mathematics, statistics, computer science, and operations research with insights from healthcare professionals to address significant challenges in the industry.

Akoustis Technologies

Grant in 2014
Akoustis Technologies, Inc. is a high-tech semiconductor company based in Huntersville, North Carolina, that specializes in the development, design, manufacturing, and sale of radio frequency (RF) filter products for the mobile wireless device industry. Established in 2013, the company operates through two main segments: Foundry Fabrication Services and RF Filters. The Foundry Fabrication Services segment offers engineering review and semiconductor wafer-manufacturing services, while the RF Filters segment focuses on producing innovative amplifier and filter products for various applications, including smartphones, tablets, cellular infrastructure, Wi-Fi equipment, and military uses. Akoustis utilizes a proprietary microelectromechanical systems-based technology known as XBAW to create its filters, enabling efficient production and unique performance characteristics. The company generates revenue primarily through individual customer purchase orders.

Alievio

Grant in 2014
Alievio, Inc. is a North Carolina-based company that specializes in the design, development, and manufacturing of innovative ophthalmic medical devices for glaucoma patients. The company has introduced a novel device, Sollevio, which offers a noninvasive method for titrating postoperative intraocular pressure in the treatment of refractory glaucoma. This device serves as a significant advancement in glaucoma therapy, aiming to address the complications associated with traditional glaucoma surgeries while providing ophthalmologists with a valuable tool to halt the progression of the disease. Founded in 2010 and originally known as Camras Vision, Inc., Alievio changed its name in June 2019 and operates from Research Triangle Park, North Carolina.

GridBridge

Grant in 2014
GridBridge is a Raleigh, North Carolina-based company founded in 2012 that designs, develops, and deploys power delivery solutions to modernize electrical grids. It specializes in grid energy router technology and platform-based systems that combine advanced electronics with software to manage power flow, integrate renewable generation and energy storage, and improve distribution efficiency and reliability for electric utilities and consumers worldwide. These solutions support grid modernization and the integration of distributed generation resources.

InfoSense

Grant in 2014
InfoSense is a technology-driven company established in 2007 as a spin-off from the University of North Carolina at Charlotte. It specializes in the commercial application of innovative acoustic inspection technology developed by Dr. Ivan Howitt. The company has patented a system that utilizes sound waves to non-invasively detect blockages in small-diameter gravity sewer pipes. By employing a portable transmitter and receiver, or a network of stationary devices, InfoSense can assess pipe conditions quickly and efficiently, achieving blockage assessments in under three minutes and at a significantly lower cost compared to traditional methods. This technology allows wastewater operators to effectively target their pipe cleaning efforts, improving resource allocation and operational efficiency in the wastewater collection industry.

SonoVol

Grant in 2013
SonoVol, Inc. is a company that develops and manufactures advanced ultrasound imaging systems tailored for the biotechnology and pharmaceutical sectors. Founded in 2012 and based in Durham, North Carolina, SonoVol offers a fully automated benchtop ultrasound platform known as Vega, which utilizes acoustic angiography technology. This imaging system streamlines preclinical screening processes by enabling researchers to quickly assess tumor size, location, morphology, and vascular density. The platform features a robotic multiplexed workflow that ensures hands-free data acquisition, enhancing throughput and standardization in studies regardless of the operator. SonoVol's technology aims to lower barriers for biologists in academic, government, and industry settings, ultimately facilitating more effective detection and treatment of tumors.

CEINT

Grant in 2013
CEINT is a collaborative research center headquartered at Duke University, investigating the environmental implications of nanomaterials. It explores their potential exposure, biological effects, and ecological impacts, involving researchers from multiple universities and international partners.

Xanofi

Grant in 2013
Xanofi, Inc. is a nanotechnology company based in Raleigh, North Carolina, that specializes in the development of nanofibers from polymers. Founded in 2010, Xanofi has introduced a new platform process that significantly enhances the efficiency of nanofiber production, making it easier for manufacturers to integrate these components into their production environments. The company focuses on creating nanofiber products that facilitate the spray or dispersion of liquids, particularly for wetlaid manufacturing. By enabling businesses to produce short and staple nanofibers at high yields, Xanofi is transforming the landscape of nanofiber manufacturing on a global scale.

GrassRoots Biotechnology

Grant in 2013
GrassRoots Biotechnology is a Durham, North Carolina-based company that specializes in developing genomic technologies for agricultural applications. The firm focuses on gene expression and other innovative agricultural technologies aimed at improving crop productivity and sustainability. It conducts research to enhance biofuel feedstocks, particularly biomass crops like switchgrass and sorghum, enabling farmers to cultivate more efficient and sustainable crops. Through its advancements in agricultural biotechnology, GrassRoots Biotechnology aims to contribute to the development of more productive farming practices.

GridBridge

Grant in 2013
GridBridge is a Raleigh, North Carolina-based company founded in 2012 that designs, develops, and deploys power delivery solutions to modernize electrical grids. It specializes in grid energy router technology and platform-based systems that combine advanced electronics with software to manage power flow, integrate renewable generation and energy storage, and improve distribution efficiency and reliability for electric utilities and consumers worldwide. These solutions support grid modernization and the integration of distributed generation resources.

Alievio

Grant in 2012
Alievio, Inc. is a North Carolina-based company that specializes in the design, development, and manufacturing of innovative ophthalmic medical devices for glaucoma patients. The company has introduced a novel device, Sollevio, which offers a noninvasive method for titrating postoperative intraocular pressure in the treatment of refractory glaucoma. This device serves as a significant advancement in glaucoma therapy, aiming to address the complications associated with traditional glaucoma surgeries while providing ophthalmologists with a valuable tool to halt the progression of the disease. Founded in 2010 and originally known as Camras Vision, Inc., Alievio changed its name in June 2019 and operates from Research Triangle Park, North Carolina.

Agile Sciences

Grant in 2012
Agile Sciences is a biotechnology company based in Raleigh, North Carolina, established in 2007. The company specializes in developing commercial solutions for the biopharma industry, particularly targeting challenges posed by antibiotic resistance and biofilms. Agile Sciences focuses on creating biopharmaceutical products that utilize small molecules, specifically aminoimidazole, to inhibit bacterial resistance mechanisms. This innovative approach enhances the efficacy of antibiotics, allowing for more effective treatment of life-threatening infections, including those associated with cystic fibrosis and chronic wounds. Through its internal research and development efforts, Agile Sciences aims to address critical needs in the healthcare sector related to antibiotic resistance.

EnSolve Biosystems

Grant in 2012
EnSolve Biosystems, Inc. is a biotechnology company that specializes in developing and manufacturing solutions for the filtration and cleaning of maritime and industrial waste. Established in 1995 and based in Raleigh, North Carolina, the company offers a range of innovative products designed to address environmental challenges. Key offerings include PetroLiminator, which effectively separates oil from water, and GF 2010, a liquid detergent that biologically dissolves and consumes grease and oils. EnSolve also produces EnCell, designed to eliminate organic waste from water, and EnFlow, a technology that employs catalytic and biotechnology processes for air filtration. Additionally, the company provides OxiBlast, which is effective in removing organic stains from water-washable surfaces and fabrics. Overall, EnSolve Biosystems focuses on creating effective biotreatment systems to promote environmental sustainability.
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