National Science Foundation

The National Science Foundation (NSF) is an independent federal agency established in 1950 and based in Alexandria, Virginia. It is dedicated to supporting research and education in science and engineering across a wide range of disciplines. The NSF provides significant non-dilutive funding, up to $1.5 million, to startups and small businesses through its America's Seed Fund initiative, which is part of the Small Business Innovation Research (SBIR) program mandated by Congress. With an operating budget of approximately $7.8 billion, the NSF is committed to advancing fundamental research and education, thus fostering innovation and technological development in the United States.

James Donlon

Program Director

Debasis Majumdar

Program Director

Graciela Narcho

Staff Associate

Sethuraman Panchanathan

Director

Past deals in New England

Thiozen

Grant in 2024
Thiozen is a company based in Belmont, Massachusetts, that specializes in innovative hydrogen gas production technology aimed at reducing greenhouse gas emissions. Founded in 2020, Thiozen employs a unique chemical process that converts hydrogen sulfide into hydrogen gas. This method not only significantly lowers greenhouse gas emissions but also allows clients to bypass the carbon emissions typically associated with hydrogen production from natural gas and the high costs linked to electrolysis. By offering a low-cost and low-emission alternative, Thiozen positions itself as a key player in the transition to cleaner energy solutions.

Champlain College

Grant in 2023
Since 1878, Champlain College has provided career-focused education to students from its hilltop campus in Burlington, Vt. Champlain's distinctive educational approach embodies the notion that true learning only occurs when information and experience come together to create knowledge. Champlain offers traditional undergraduate and online undergraduate courses, along with online certificate and degree programs and eight master's degree programs. Champlain offers study abroad programs at its campuses in Montreal, Quebec and Dublin, Ireland. Champlain College is included in the Princeton Review's “The Best 376 Colleges: 2012 Edition.” Champlain was named a "Top-Up-and-Coming School" by U.S. News & World Report's America's Best Colleges and is ranked in the top tier of 2012 Regional Colleges in the North

The Engine

Grant in 2023
The Engine, established by the Massachusetts Institute of Technology (MIT) in 2016, is a venture firm focused on supporting early-stage companies that tackle significant global challenges through innovative science and engineering. The Engine prioritizes transformative ideas over immediate profitability, offering a streamlined system that accelerates the progression from concept to market. It provides a physical workspace for startups, along with essential resources such as business planning, legal assistance, and administrative support. The Engine also connects entrepreneurs with "patient capital" from like-minded investors, allowing startups to maintain greater control over their ventures. With plans to support up to 60 startups simultaneously over a 12-month period, The Engine aims to facilitate rapid development and validation of groundbreaking concepts. Additionally, it offers access to specialized equipment and lab space through the Engine Room, fostering a collaborative environment that nurtures innovation within the MIT community and beyond.

Rapid7

Grant in 2023
Rapid7 is a Boston-based cybersecurity company founded in 2000, specializing in security data and analytics solutions that empower organizations to adopt a proactive approach to cybersecurity. Originally focused on vulnerability management, the company has expanded its offerings to include extended detection and response, security information and event management, cloud security, threat intelligence, application security, and security orchestration, automation, and response. Rapid7 provides a range of services such as detection and response, vulnerability management, security advisory services, and IoT security testing, aiming to enhance organizations' security postures through innovative solutions and active engagement in the cybersecurity community.

Remedium Bio

Grant in 2023
Remedium Bio is a Boston-based gene therapy company dedicated to developing curative treatments for various debilitating conditions. The company employs a modular approach to research and development, utilizing established technologies in innovative ways to address well-understood disease mechanisms. By focusing on clinically validated molecules and targeted treatment strategies, Remedium Bio aims to create effective therapies for conditions within rheumatology, endocrinology, and neurology. Its pipeline includes promising gene therapy candidates designed to tackle a wide range of diseases, including immune and age-related disorders.

Quantivly

Grant in 2023
Quantivly, Inc. is a technology company based in Somerville, Massachusetts, that specializes in artificial intelligence solutions for radiology. Founded in 2019, it focuses on developing software that manages and analyzes MRI imaging workflows. The company's platform enables radiology providers to access a vendor-neutral, granular source of operational data by analyzing and harmonizing scanner information. This capability supports radiology departments and imaging centers in making data-driven decisions, improving operational efficiency, and enhancing patient-centered healthcare. By offering tools for data liquidity and analysis, Quantivly aims to increase access to medical imaging and drive advancements in research and patient care within the radiology sector.

University of Massachusetts Amherst

Grant in 2023
The University of Massachusetts Amherst is a public research and land-grant university that offers undergraduate, master's, and doctoral programs. It serves as the flagship campus of the University of Massachusetts system. The university has multiple academic departments and research facilities that support a range of disciplines.

Rich Earth Institute

Grant in 2022
Rich Earth Institute, established in 2012 and located in Brattleboro, Vermont, focuses on research and education to promote the use of human waste as a valuable resource. The organization develops technologies for urine-collecting portable toilets, facilitating a sustainable approach to waste management. By implementing a community-scale urine recycling program, Rich Earth Institute enables the diversion, collection, treatment, and application of urine for agricultural purposes. This innovative platform not only ensures a cleaner environment for communities but also fosters the beneficial use of human waste in farming and gardening practices.

QSimulate

Grant in 2022
QSimulate is a Boston-based company that develops cloud-based quantitative simulation tools aimed at addressing complex challenges in the chemical and pharmaceutical industries. By harnessing the principles of quantum mechanics, QSimulate’s platform facilitates quantum molecular simulations, allowing clients to tackle industrial-scale problems more effectively. The tools offered by the company automate workflows, relieving computational scientists of routine tasks and thereby increasing productivity. This innovation enables organizations to accelerate their research and development processes, ultimately enhancing their capacity to innovate and solve critical issues in their fields.

Singularity Energy

Grant in 2022
Singularity Energy, Inc. is a company focused on developing real-time carbon tracking and decision-making solutions aimed at helping corporate customers optimize their energy usage and reduce carbon emissions. Founded in 2018 by Wenbo Shi, the company utilizes artificial intelligence to integrate real-time carbon dioxide signals from the grid into its platform. This technology enables businesses, including climate regulators and sustainability directors, to visualize and co-optimize their energy resources while balancing cost and emissions. Based in Cambridge, Massachusetts, Singularity Energy provides essential data infrastructure that supports grid decarbonization efforts, allowing organizations to meet their sustainability targets with confidence and transparency.

Belmont Scientific

Grant in 2022
Belmont Scientific is a chemical and battery safety technology company that specializes in process safety and risk management. The company was founded in 2011 and is based in Lowell, Massachusetts.

Lura Health

Grant in 2022
Lura Health has developed a groundbreaking non-invasive health monitoring platform that utilizes saliva as a diagnostic fluid, aiming to enhance clinical outcomes in chronic disease management. Founded in 2017 and based in Cambridge, Massachusetts, the company targets various chronic disease markets, including heart disease, chronic kidney disease, diabetes, and tooth decay. Its innovative sensors are integrated into patient-friendly orthodontic devices such as removable retainers and fixed braces. These sensors continuously measure analytes in saliva and automatically transmit data to a smartphone application, allowing users to track key diagnostic metrics related to their oral health. By enabling individuals to monitor their health in real-time, Lura Health seeks to improve personal health management and empower users to take charge of their well-being.

Bactana

Grant in 2022
Bactana Corporation focuses on researching and developing nutritional products aimed at enhancing microbiome health in livestock and pets. The company has created a product platform called FPS-4, which leverages the beneficial interaction between an animal’s immune system and metabolism to boost productivity while ensuring good health. Bactana's approach includes identifying and isolating beneficial molecules from anaerobic bacteria found in the animal microbiome. The company also targets metabolic conditions and digestive disorders in pets, aiming to develop therapies for issues such as prediabetes and diabetes. Additionally, Bactana is committed to creating sustainable products that reduce the reliance on antibiotics and conserve natural resources in livestock production. Founded in 2016 and headquartered in Farmington, Connecticut, Bactana serves cattle farmers primarily in Connecticut and New York.

Dynocardia

Grant in 2022
Dynocardia, a biomedical device development company, committed to satisfying critical unmet needs to improve healthcare. It offers direct, beat-to-beat measurement of blood pressure that is wrist-wearable, mobile, and easy to use, with the accuracy of intra-arterial lines. The company was founded in 2018 and headquartered in Lowell, Massachusetts.

AM Batteries

Grant in 2022
AM Batteries manufactures Li-ion batteries using solvent-free electrode manufacturing technology. The company was founded in 2016 and is headquartered in Chelmsford, Massachusetts.

Boston Geospatial

Grant in 2021
Boston Geospatial specializes in delivering geospatial insights tailored for operators and risk managers within critical infrastructure sectors. The company has developed a comprehensive geospatial data platform that facilitates access to various satellite data providers. This platform allows users to search, compare, and analyze data in multiple ways, thereby enhancing decision-making processes and risk assessment. By offering ready-to-use insights, Boston Geospatial supports effective management and operational efficiency in vital industries.

Thiozen

Grant in 2021
Thiozen is a company based in Belmont, Massachusetts, that specializes in innovative hydrogen gas production technology aimed at reducing greenhouse gas emissions. Founded in 2020, Thiozen employs a unique chemical process that converts hydrogen sulfide into hydrogen gas. This method not only significantly lowers greenhouse gas emissions but also allows clients to bypass the carbon emissions typically associated with hydrogen production from natural gas and the high costs linked to electrolysis. By offering a low-cost and low-emission alternative, Thiozen positions itself as a key player in the transition to cleaner energy solutions.

Chibitronics

Grant in 2021
Chibitronics is an evolution of Jie Qi’s passion for combining technology and art through making electronics using paper craft. The circuit stickers were developed as part of her PhD research at the MIT Media Lab. Together with Andrew “bunnie” Huang and Patricia Ng, Jie’s research has evolved into the Chibitronics toolkits. We hope to share this new way of learning circuits and creating artwork, so that everyone can become technology creators!

Biko Biolabs

Grant in 2021
Biko Biolabs is a research company focused on the intersection of plastic waste and regenerative agriculture. The company was founded in 2020 and is based in Somerville, Massachusetts.

Skyhaven Systems

Grant in 2021
Skyhaven Systems is a research and development firm headquartered in Steamboat Springs, Colorado, with primary laboratories in Westford, Massachusetts. Established in 2017 through the merger of Reactive Innovations, LLC, the company specializes in addressing critical needs of the U.S. Government across the Defense, Energy, Aerospace, and Environmental sectors. Skyhaven employs advanced electrochemical engineering and reaction-based chemistry to tackle complex technical challenges, working closely with agencies such as the Department of Defense, NASA, and the Environmental Protection Agency. The firm focuses on innovative chemical process technologies, including reactor design and thermal management, to develop operational prototypes and deliver research findings. As a small business, Skyhaven retains technology rights from its government-funded projects, providing the government with a royalty-free license while also enabling the firm to pursue commercialization opportunities. This strategic approach allows Skyhaven to address high-risk development areas often overlooked by larger organizations, fostering innovation through government contracts and grants. The firm actively protects its intellectual property through patents and trade secrets, positioning itself for future growth in both governmental and commercial markets.

MedChem Partners

Grant in 2021
MedChem Partners is a medicinal chemistry CRO that specializes in developing small molecule therapeutics. The company was founded in 2006 and is headquartered in Lexington, Massachusetts.

Theromics

Grant in 2021
Theromics Inc. is a biotechnology company focused on developing innovative cell therapies, particularly in the field of thermal ablation for cancer treatment. Founded in 2016 and based in West Bridgewater, Massachusetts, the company has created HeatSYNC Gel, a biopolymer thermal accelerant designed to enhance the effectiveness of microwave and radiofrequency ablation procedures. This gel improves the delivery and absorption of thermal energy in soft tissue and bone, optimizing the ablation zone's shape and volume. By increasing local tissue electrical conductivity, HeatSYNC Gel helps to prevent heat loss due to blood flow, allowing for more precise targeting of tumors and protecting surrounding healthy tissue. The gel can be administered through various methods, including syringe, laparoscope, and bronchoscope, and is intended to improve the overall efficacy of thermal ablation therapies while enabling personalized treatment approaches.

Simpact

Grant in 2021
Simpact develops analytics and forecasting software to help businesses make data-driven decisions. The company's headquarters are in Boston, Massachusetts.

Xheme

Grant in 2021
Xheme is a technology company based in Newton, Massachusetts, founded in 2019. The company specializes in developing advanced blood bag technology that enhances the shelf life of blood and platelets. In addition to its focus on the healthcare sector, Xheme also creates specialty chemicals aimed at improving product quality, sustainability, and safety across various industrial applications. Its innovative products are designed to be programmable, offering multiple protective functions such as resistance to oxidation, ultraviolet light, corrosion, and microbial threats. This dual approach enables industries to preserve both the aesthetic and functional integrity of their products over time.

Heila Technologies

Grant in 2021
Heila Technologies develops a platform that connects solar arrays, batteries, and other distributed energy resources (DERs) to create self-managing microgrids. The Heila IQ Platform is a decentralized optimization system that simplifies the integration and operation of these resources, allowing for autonomous management and optimization. This technology transforms various components, such as batteries and solar arrays, into independent intelligent agents capable of self-organization and regulation. Heila Technologies serves a diverse clientele, including utility representatives, developers, energy users, and public officials. Founded in 2017 and based in Somerville, Massachusetts, the company aims to facilitate the commercialization of its platform, providing granular analysis and data-driven recommendations to enhance the resilience and efficiency of energy networks while promoting energy savings and reducing carbon emissions.

Irradiant Technologies

Grant in 2021
Irradiant Technologies, founded in 2020 and based in Cambridge, Massachusetts, specializes in advanced nanofabrication utilizing implosion fabrication lithography. The company focuses on developing a platform that facilitates the ultrafast three-dimensional assembly of mixed materials, such as conductors, semiconductors, dielectrics, proteins, and DNA, with nanoscale precision and gradient control. This innovative approach enables the creation of novel photonic and optical components, providing light-based alternatives for applications in telecommunications, computation, and sensing.

Aliro Technologies

Grant in 2021
Aliro Technologies, Inc., founded in 2019 and headquartered in Boston, Massachusetts, specializes in developing cloud-based software for quantum computing. The company's platform provides a hardware-independent toolkit that facilitates the creation of quantum algorithms and applications, catering to developers in the quantum environment. Known for its product AliroNet™, the company focuses on emulating, piloting, and deploying entanglement-based quantum networks that support various applications, including secure communications and distributed quantum sensing. Emerging from NarangLab at Harvard University, Aliro Technologies boasts a team of experts in quantum and classical networking and actively contributes to the advancement of quantum networking technologies. Its users range from utility companies and telecommunications providers to public sector organizations and researchers engaged in building scalable quantum systems. The company collaborates with industry and academic partners through initiatives like the Quantum Economic Development Consortium and the NSF Center for Quantum Networks, while also participating in several quantum networking standards groups.

FluidForm Bio

Grant in 2021
FluidForm Bio is a biotechnology company focused on creating living human tissue to enhance disease treatment. Utilizing its patented FRESH technology, the company specializes in 3D bioprinting, which enables the production of high-quality tissue that mimics real human tissue by integrating cells and proteins without additional materials. This innovative platform allows for the design and fabrication of complex tissue structures with embedded vasculature and multiple materials within a single print. Through collaborations with leading life science companies, FluidForm Bio's technology has been validated for various applications, paving the way for novel therapeutic programs in the healthcare sector. Founded in 2018 and headquartered in Waltham, Massachusetts, FluidForm Bio aims to provide better treatment options for patients through its transformational approach to tissue engineering.

Silartek

Grant in 2021
SilarTek, founded in 2020 and based in Leominster, Massachusetts, focuses on developing innovative solar silicon technology to enhance the affordability of solar panels. The company employs molten salt electrolysis combined with advanced molten salt compositions to produce low-cost solar-grade silicon. This technology aims to make solar energy more accessible to a broader consumer base, facilitating the adoption of renewable energy solutions.

SiTration

Grant in 2021
SiTration improves ultra-durable filtration membranes intended for efficient separations in the harshest environments. Brendan Smith established the company in Cambridge, Massachusetts in 2020.

Enable Therapeutics

Grant in 2021
Enable Therapeutics is a biotechnology company developing a patented drug delivery platform. The company was founded in 2020 and is headquartered in Hopedale, Massachusetts.

Junora

Grant in 2021
Junora LTD is a manufacturer based in Biddeford, Maine, specializing in rotary and planar sputter targets for the thin film deposition industry. Founded in 2017, the company provides a diverse range of thin film deposition products, including rotary and planar targets, as well as target fabrication services, engineering design, and precision machining. Junora offers its products in various materials such as aluminum, copper, indium, lithium, silver, tin, zinc, and custom alloys. The company's solutions cater to markets that require thin film coatings applied through vacuum deposition, enabling clients to access a wide array of sputtering targets through established manufacturing processes.

Quantivly

Grant in 2021
Quantivly, Inc. is a technology company based in Somerville, Massachusetts, that specializes in artificial intelligence solutions for radiology. Founded in 2019, it focuses on developing software that manages and analyzes MRI imaging workflows. The company's platform enables radiology providers to access a vendor-neutral, granular source of operational data by analyzing and harmonizing scanner information. This capability supports radiology departments and imaging centers in making data-driven decisions, improving operational efficiency, and enhancing patient-centered healthcare. By offering tools for data liquidity and analysis, Quantivly aims to increase access to medical imaging and drive advancements in research and patient care within the radiology sector.

Thinking Robots

Grant in 2020
Thinking Robots, founded in 2010 and based in Boston, Massachusetts, specializes in software solutions for robotic tasks applicable across various robotic platforms. The company develops custom software that integrates natural language dialogue, sensors, and actuators to enhance robotic architecture. This technology enables robots to interact with humans and includes high-level planning capabilities, allowing developers to create interactive and teachable robots that can be directly instructed by users.

Millimeter Wave Systems

Grant in 2020
Millimeter Wave Systems provides millimeter wave and microwave hardware solutions like subsystems, modules, components, and antennas. The company was founded in 2016 and is headquartered in Amherst, Massachusetts.

Paramount Planet Product

Grant in 2020
Paramount Planet Product is a startup based in Orono focused on reducing ocean pollution through the development of low-cost, compostable plant-based packaging. The company's innovative products mimic the characteristics of plastic while being environmentally safe, as they are designed to break down in ocean environments without causing harm. By utilizing ocean compostable materials, Paramount Planet Product aims to enhance packaging performance while minimizing environmental impact. Their commitment to creating fish-friendly packaging addresses the urgent need for sustainable solutions in single-use items, allowing customers to adopt environmentally responsible practices in their operations.

Armada Marine Robotics

Grant in 2020
Armada Marine Robotics develops asymmetric propulsion technology for enhancing marine maneuverability. The company's headquarters are in Falmouth, Massachusetts.

Full Circle Microbes

Grant in 2020
Full Circle Microbes provides a waste disposal service that converts organic waste into fertilizer. The company was founded in 2019 and is headquartered in Hinesburg, Vermont.

ActivSignal

Grant in 2020
ActivSignal is a biotech company that develops protein profiling for diagnostics and other applications. The company was founded in 2016 and is headquartered in Natick, Massachusetts.

Travera

Grant in 2020
Travera, LLC is a biotechnology company based in Cambridge, Massachusetts, founded in 2017. It specializes in a unique measurement technology that utilizes the Suspended Microchannel Resonator (SMR), a MEMS device capable of detecting minute changes in the weight of individual cancer cells. This technology focuses on the Mass Accumulation Rate (MAR) biomarker, which indicates how cancer cells respond to various drugs within hours of exposure. By measuring these rapid changes, Travera enables oncologists to make informed decisions about which therapies to prescribe based on the actual responses of a patient’s tumor cells. This approach aims to enhance the effectiveness of cancer treatment by distinguishing between natural cell death and drug-induced cell death, thereby improving patient outcomes.

Lura Health

Grant in 2020
Lura Health has developed a groundbreaking non-invasive health monitoring platform that utilizes saliva as a diagnostic fluid, aiming to enhance clinical outcomes in chronic disease management. Founded in 2017 and based in Cambridge, Massachusetts, the company targets various chronic disease markets, including heart disease, chronic kidney disease, diabetes, and tooth decay. Its innovative sensors are integrated into patient-friendly orthodontic devices such as removable retainers and fixed braces. These sensors continuously measure analytes in saliva and automatically transmit data to a smartphone application, allowing users to track key diagnostic metrics related to their oral health. By enabling individuals to monitor their health in real-time, Lura Health seeks to improve personal health management and empower users to take charge of their well-being.

Metalmark Innovations

Grant in 2020
Metalmark Innovations, Inc. develops advanced 3D nanostructured coatings designed to treat airborne pollutants and toxins, thereby enhancing indoor air quality. The company offers its innovative materials as coating additives for various applications, including building materials and vehicle interiors. Its technology effectively targets and breaks down harmful substances such as hydrocarbons, carbon monoxide, ozone, PM2.5, volatile organic compounds, odors, and germs in diverse transportation settings, including airplanes, ships, trains, cars, and buses. Founded in 2017 and based in Boston, Massachusetts, Metalmark Innovations aims to address the pressing challenges of air pollution and climate change through its cutting-edge air cleaning solutions. The company was previously known as Aircrew Technologies, Inc. before rebranding in January 2019.

Infinite Cooling

Grant in 2020
Infinite Cooling Inc. specializes in water recovery systems designed for power plants and other industrial facilities. Founded in 2017 and based in Massachusetts, the company focuses on mitigating water scarcity by employing innovative technology that utilizes high-voltage electric fields to capture and recycle water evaporating from cooling towers. This approach allows power plants, data centers, and factories to significantly reduce water consumption and treatment costs, thereby promoting more sustainable operations. Through its efforts in wastewater management and recycling, Infinite Cooling aims to address environmental challenges related to water waste in industrial processes.

Veramorph

Grant in 2020
VeraMorph is a pharmaceutical company established in 2017 and located in Mansfield, Massachusetts. The company specializes in developing an innovative oral drug delivery technology centered around proprietary oral hydrogel tablets. This technology is designed to enhance drug stability, expedite dissolution rates, and maintain prolonged high saturation levels, allowing for higher drug loading compared to existing formulations. By providing contract manufacturing and formulation services, VeraMorph aims to assist pharmaceutical companies in improving the performance of their products while reducing both costs and the time required to bring new drugs to market.

Ichosia Biotechnology

Grant in 2020
Ichosia Biotechnology, founded in 2019 and based in Worcester, Massachusetts, focuses on the development of derived red blood cells by leveraging natural genetic processes. The company has created a platform that genetically engineers human stem cells to produce red blood cells, aiming to support healthcare providers and patients in need. This innovative approach enables the provision of blood on demand for patients at risk, addressing critical shortages and improving patient care in medical settings.

Biocogniv

Grant in 2020
Biocogniv Inc. specializes in developing artificial intelligence-powered diagnostic tools designed for hospitals, with a focus on enhancing clinical operations. Founded in 2019 and based in Burlington, Vermont, the company provides plugins for electronic health record (EHR) systems that enable real-time screening of patients for conditions such as COVID-19 by analyzing standard blood test results. Biocogniv's platform is particularly beneficial for emergency departments, as it can predict sepsis-related mortality and the need for intensive care unit admission. By leveraging the vast amounts of clinical and administrative data generated by hospitals, Biocogniv aims to improve the quality, cost, and accessibility of healthcare while facilitating accurate and non-invasive diagnostic methods.

Neuright

Grant in 2020
Neuright is a biotech company that develops theragnostic devices for peripheral neuropathy. The company was founded in 2018 and is headquartered in Orono, Maine.

GelSight

Grant in 2020
GelSight, Inc. specializes in advanced sensor technology solutions for precise surface measurements. The company has developed the GelSight benchtop scanner, which captures the surface geometry of various materials and accurately measures rigid objects across a wide range of scales. Their innovative technology allows for detailed three-dimensional visualization and measurement, revealing features that are not discernible to the naked eye, and providing dimensional accuracy to single-digit microns. GelSight's products are utilized in diverse sectors, including aerospace, electronics, and forensics, as well as in academic and research environments. Founded in 2011 and headquartered in Waltham, Massachusetts, GelSight continues to enhance its offerings while addressing the evolving surface measurement needs of its clients.

Boston Materials

Seed Round in 2020
Boston Materials, Inc. is a manufacturer of advanced composite materials, specializing in 3D reinforced carbon fiber pre-pregs. Founded in 2016 and based in Bedford, Massachusetts, the company utilizes patented Z-axis Fiber technology, which incorporates vertically aligned carbon fibers to enhance energy transfer properties. Its product line includes Carbon Supercomposite, a magnetically assembled carbon fiber pre-preg, which finds applications across various sectors such as aerospace, automotive, marine, wind energy, and sports equipment. Boston Materials' advanced materials aim to improve thermal, electrical, and mechanical properties, offering a roll-to-roll manufacturing process with in-line quality control and an annual production capacity of one million square meters. These innovations enable industries like semiconductors and electrified vehicles to achieve greater efficiency, reliability, and weight reduction while addressing critical challenges in durability and performance.

Bitome

Grant in 2020
Bitome is a two-year-old, Boston-based connected med device company. Its first product is a noninvasive tool for monitoring hydration status with broad applications across the dialysis, diabetic, sports performance, and maternal / fetal monitoring spaces. In a first application, Bitome’s technology will precisely assess volume status in congestive heart failure (CHF) patients – a key, but hard to measure, biometric correlated with patient outcomes. In short, Bitome wants to use hydration monitoring technology to do for CHF, what glucose monitoring has done for diabetes.

Quinsigamond Community College

Grant in 2020
Quisigamond Community College, located in Worcester, MA, serves over 13,000 students and offers more than 70 associate degree and certificate programs. In addition to the traditional student academic program, Quisigamond offers online classes specifically geared toward working students or professionals who want to enhance their skills or build new ones. Those classes include Business Administration, Fire Science, Criminal Justice, Computer Science and Hospitality Management. Certificates are available in business administration/insurance or medical office options, Hotel and Restaurant Management, Early Childhood Education, and Law Enforcement. Various healthcare certificates are also offered including Surgery Technology, basic Paramedic and Dental Assisting. Associate Degrees are offered in Deaf Studies, Biomedical Engineering, Electromechanical Technology, Telecommunications Technology and Energy Utility. Quisigamond has developed outstanding relationships with potential employers in the central Massachusetts area including Intel, Verizon, Kennedy Diecasting, UPS and Ken-Weld and sponsors regular collaborations for workforce training. The Children’s School is available for enrolled students and members of the community with children between the ages of 2 to 5 years and also operates as a training center for Early Childhood Education students . The Division of Continuing Education hosts non-credit courses, workshops and seminars that are widely attended by the community and students.

Singularity Energy

Grant in 2019
Singularity Energy, Inc. is a company focused on developing real-time carbon tracking and decision-making solutions aimed at helping corporate customers optimize their energy usage and reduce carbon emissions. Founded in 2018 by Wenbo Shi, the company utilizes artificial intelligence to integrate real-time carbon dioxide signals from the grid into its platform. This technology enables businesses, including climate regulators and sustainability directors, to visualize and co-optimize their energy resources while balancing cost and emissions. Based in Cambridge, Massachusetts, Singularity Energy provides essential data infrastructure that supports grid decarbonization efforts, allowing organizations to meet their sustainability targets with confidence and transparency.

DeepHealth

Grant in 2019
DeepHealth, Inc. is a radiology artificial intelligence and machine learning company based in Cambridge, Massachusetts, founded in 2015. The company specializes in developing solutions for the medical interpretation of mammography exams, leveraging data science and imaging analysis to support radiologists in their diagnostic processes. By utilizing machine learning, DeepHealth distills extensive insights from medical experts into software designed to enhance the accuracy and reliability of radiological assessments. The company's mission is to improve patient care by providing trustworthy products that are grounded in rigorous scientific research and integrated into clinical practice.

Sober Grid

Grant in 2019
Sober Grid, Inc. operates a digital health platform that serves as a sober social network, facilitating connections among individuals recovering from substance use disorders. Launched in 2015 and headquartered in Boston, Massachusetts, the application is available on both Apple and Android devices and has been utilized over 20 million times across more than 170 countries. Developed in collaboration with researchers from Harvard Medical School and the University of Pennsylvania, Sober Grid employs a community-based approach to chronic disease management, incorporating evidence-based recovery tools and predictive analytics to assess relapse risk. The app features a GPS locator for users to find nearby sober individuals, along with direct messaging, a newsfeed, and access to certified coaching available 24/7. By combining technology with human connection, Sober Grid aims to improve health outcomes through real-time support and engagement, catering to a growing population of individuals in recovery.

Infinite Cooling

Grant in 2019
Infinite Cooling Inc. specializes in water recovery systems designed for power plants and other industrial facilities. Founded in 2017 and based in Massachusetts, the company focuses on mitigating water scarcity by employing innovative technology that utilizes high-voltage electric fields to capture and recycle water evaporating from cooling towers. This approach allows power plants, data centers, and factories to significantly reduce water consumption and treatment costs, thereby promoting more sustainable operations. Through its efforts in wastewater management and recycling, Infinite Cooling aims to address environmental challenges related to water waste in industrial processes.

Elephant Stem

Grant in 2019
Elephant Stem develops a video game platform to assist students in learning statistics. The company is based in Cambridge, Massachusetts.

Heila Technologies

Grant in 2019
Heila Technologies develops a platform that connects solar arrays, batteries, and other distributed energy resources (DERs) to create self-managing microgrids. The Heila IQ Platform is a decentralized optimization system that simplifies the integration and operation of these resources, allowing for autonomous management and optimization. This technology transforms various components, such as batteries and solar arrays, into independent intelligent agents capable of self-organization and regulation. Heila Technologies serves a diverse clientele, including utility representatives, developers, energy users, and public officials. Founded in 2017 and based in Somerville, Massachusetts, the company aims to facilitate the commercialization of its platform, providing granular analysis and data-driven recommendations to enhance the resilience and efficiency of energy networks while promoting energy savings and reducing carbon emissions.

AmberWave

Grant in 2019
AmberWave, Inc. is a research and development company specializing in photovoltaic technology solutions and semiconductor manufacturing, aimed at serving commercial and industrial sectors, as well as unmanned aerial vehicles. Founded in 1998 and headquartered in Ipswich, Massachusetts, the company focuses on advanced substrate engineering for integrated circuits, semiconductor lighting, and photovoltaics. AmberWave’s notable technologies include Strained Silicon, which enhances microchip performance while reducing power consumption, and Aspect Ratio Trapping, utilized in the production of silicon-based photonics and photovoltaic cells. Previously known as AmberWave Systems Corporation, the company rebranded in 2010 and continues to develop high-value materials for emerging markets and applications.

University of Massachusetts, Lowell

Grant in 2019
University of Massachusetts Lowell is a high-ranking university, with several nationally recognized academic departments. Located about 30 minutes from Boston in Lowell, Massachusetts, UMass Lowell offers more than 100 degree programs at the undergraduate and graduate levels. UMass Lowell has several nationally recognized, research-oriented programs, including science and engineering. These programs undertake groundbreaking research and also provide exceptional work opportunities for its students and graduates. Other programs at UMass Lowell include liberal and fine arts, humanities, health-related programs, teacher education and social sciences. UMass Lowell also offers a range of internship opportunities for students who wish to gain experience in their field of study. Student life options at UMass Lowell include more than 100 diverse student organizations, leadership programs and community service opportunities. Lowell’s admissions policies are moderately competitive. Financial aid is available to eligible students through loans, academic scholarships and other sources to help cover tuition.

Travera

Grant in 2019
Travera, LLC is a biotechnology company based in Cambridge, Massachusetts, founded in 2017. It specializes in a unique measurement technology that utilizes the Suspended Microchannel Resonator (SMR), a MEMS device capable of detecting minute changes in the weight of individual cancer cells. This technology focuses on the Mass Accumulation Rate (MAR) biomarker, which indicates how cancer cells respond to various drugs within hours of exposure. By measuring these rapid changes, Travera enables oncologists to make informed decisions about which therapies to prescribe based on the actual responses of a patient’s tumor cells. This approach aims to enhance the effectiveness of cancer treatment by distinguishing between natural cell death and drug-induced cell death, thereby improving patient outcomes.

Metalmark Innovations

Grant in 2019
Metalmark Innovations, Inc. develops advanced 3D nanostructured coatings designed to treat airborne pollutants and toxins, thereby enhancing indoor air quality. The company offers its innovative materials as coating additives for various applications, including building materials and vehicle interiors. Its technology effectively targets and breaks down harmful substances such as hydrocarbons, carbon monoxide, ozone, PM2.5, volatile organic compounds, odors, and germs in diverse transportation settings, including airplanes, ships, trains, cars, and buses. Founded in 2017 and based in Boston, Massachusetts, Metalmark Innovations aims to address the pressing challenges of air pollution and climate change through its cutting-edge air cleaning solutions. The company was previously known as Aircrew Technologies, Inc. before rebranding in January 2019.

Helios Applied Science

Grant in 2019
Helios Applied Science develops ultra-portable innovations for first-response rescue and humanitarian relief. The company is based in Hyde Park, Massachusetts.

ActivSignal

Grant in 2019
ActivSignal is a biotech company that develops protein profiling for diagnostics and other applications. The company was founded in 2016 and is headquartered in Natick, Massachusetts.

3Derm Systems

Grant in 2019
3Derm Systems, Inc. is a Boston-based company that specializes in 3D dermatology solutions. Founded in 2011, it has developed a handheld skin imager along with cloud-based software that enables users to capture, store, and transmit high-resolution 3D images of the skin to dermatologists. This innovative system allows non-dermatologists to take clinical-quality images remotely, facilitating efficient monitoring of skin conditions, particularly for patients at risk of skin cancer. By enabling images to be reviewed at medical kiosks and other referral sites, 3Derm helps dermatologists manage high patient volumes while reserving in-office visits for those requiring immediate attention. The company's approach aims to reduce healthcare costs, decrease wait times, and enhance access to dermatological care, allowing patients to monitor their skin from home instead of making frequent, often inconvenient, clinic appointments. 3Derm Systems operates as a subsidiary of Digital Diagnostics, Inc. as of August 2020.

Millimeter Wave Systems

Grant in 2019
Millimeter Wave Systems provides millimeter wave and microwave hardware solutions like subsystems, modules, components, and antennas. The company was founded in 2016 and is headquartered in Amherst, Massachusetts.

Gel4Med

Grant in 2019
Gel4Med LLC is a Boston-based medical technology company established in 2015, specializing in the development of innovative biomaterials for tissue treatment and regeneration. The company focuses on creating an antimicrobial tissue-scaffolding matrix designed to eliminate antibiotic-resistant bacteria while promoting tissue regeneration. By utilizing bioinspired and engineered materials, Gel4Med aims to address significant healthcare challenges, particularly in wound care. Their leading technology employs a self-assembling peptide mechanism that acts as both an antibacterial barrier and a promoter of tissue regeneration, thus enhancing patient outcomes and preventing infections during surgical procedures.

Root AI

Grant in 2019
Root AI, Inc. is a company that specializes in manufacturing artificial intelligence robots designed for indoor farming. Founded in 2018 and based in Woburn, Massachusetts, the company has developed Virgo 1, an autonomous robot specifically engineered for harvesting tomatoes. This robot excels in picking tomatoes without causing bruising and can assess ripeness with greater accuracy than human laborers. Root AI aims to enhance the efficiency of indoor agriculture by integrating advanced vision systems and AI technology, enabling growers to produce high-quality, chemical-free crops while maximizing productivity in smart farm environments.

Vaxess Technologies

Grant in 2018
Vaxess Technologies, Inc. is a biotechnology company based in Boston, Massachusetts, founded in 2011. The company focuses on developing and commercializing innovative silk biomaterial technologies. Its key product, the MIMIX microneedle platform, facilitates the transdermal delivery of vaccines and therapeutics. This sustained release patch technology allows for a controlled release of vaccines, mimicking the natural infection process to enhance immune response and effectiveness. Vaxess's patch is engineered for stability, eliminating the need for refrigeration, which enables shipping and application in low-resource settings. In addition to its vaccine delivery systems, Vaxess is also engaged in creating novel therapies aimed at oncology care and infectious diseases, ultimately striving to improve patient outcomes with reduced treatment burdens.

Nanoview Biosciences

Grant in 2018
NanoView Biosciences is a biotechnology company that specializes in the development of technologies for the characterization of extracellular vesicles, particularly exosomes. Founded in 2015 and based in Boston, Massachusetts, the company utilizes its proprietary ExoView technology to provide high-throughput and cost-effective analysis solutions for life science researchers. NanoView's products, which include the ExoView R100 and ExoView tetraspanin, enable precise detection and multiparametric characterization of exosomes from complex biological samples such as blood, serum, plasma, and urine. In addition to its core products, the company offers custom assays, sample services, and a support platform to aid researchers in understanding the biological roles of exosomes and utilizing them as biomarkers for disease diagnosis, treatment, and monitoring.

Via Separations

Grant in 2018
Via Separations, Inc. is focused on developing innovative membrane-based products for industrial liquid separation in challenging environments. Founded in 2016 and based in Somerville, Massachusetts, the company aims to address the significant energy waste in the chemical separation process, which accounts for 12% of U.S. energy consumption. By employing its advanced membrane technology, Via Separations can reduce energy use by up to 90% and enhance product output. Their highly selective and robust membrane filters replace traditional heat-based separation methods, contributing to industrial decarbonization efforts. The company is currently conducting pilot trials in pulp and paper facilities, with the goal of eliminating 100 million metric tons of CO2 emissions by 2050. Originating from MIT's Department of Material Science & Engineering, Via Separations has successfully scaled its technology and demonstrated working prototypes at a commercial level.

Elektrofi

Grant in 2018
Elektrofi is a preclinical-stage company based in Boston, Massachusetts, focused on advancing drug delivery methods to enhance patient experiences. Established in 2016, the company has developed a formulation system capable of processing a diverse array of therapeutic molecules, including large and complex proteins such as monoclonal antibodies, bispecifics, and fusion proteins. Its innovative technology aims to improve subcutaneous administration, allowing drug manufacturers to create breakthrough therapies that empower patients with more control over how they receive essential medications.

The University of Vermont Health Network

Grant in 2018
Welcome to The University of Vermont Health Network, five partner hospitals serving the residents of Vermont and northern New York. With over 4,000 health care providers throughout our region, they work together to offer high-quality care more cost-efficiently and as close to home as possible. Strengthened by their connection, each of their hospitals remains committed to its local community and to the heart and science of medicine: compassionate, personal care shaped by the latest medical advances and delivered by highly skilled experts.

University of Massachusetts Amherst

Grant in 2018
The University of Massachusetts Amherst is a public research and land-grant university that offers undergraduate, master's, and doctoral programs. It serves as the flagship campus of the University of Massachusetts system. The university has multiple academic departments and research facilities that support a range of disciplines.

KnipBio

Grant in 2018
KnipBio is a biotechnology company that develops responsible and sustainable commercial feed solutions for the aquaculture industry. It is committed to solving real-world challenges by working with global corporations. Its game-changing single-cell protein combines the attributes of premium, protein-packed fishmeal, and carotenoids into a single effective and affordable fishmeal replacement -- KnipBio Meal (KBM). KBM is a transformative breakthrough in the future of aquaculture feed. It was founded in 2013 and is based in Lowell, Massachusetts.

AI Strike

Grant in 2018
AI Strike provides big data and AI technology solutions and decision support systems that improve the bottom line of clients. The company's headquarters are in Shrewsbury, Massachusetts.

Resonant Link

Grant in 2018
Resonant Link LLC, founded in 2017 and based in Shelburne, Vermont, specializes in the development of advanced wireless charging solutions utilizing innovative coil technology. The company's signature product, the multi-layer self-resonant structure (MSRS), enhances the efficiency and performance of wireless power systems. Serving diverse industries including robotics, drones, and electric vehicles, Resonant Link aims to deliver wireless power solutions that are fast, safe, and reliable. By eliminating costly components found in traditional wireless chargers, Resonant Link's technology not only improves efficiency but also reduces the size, weight, and overall cost of charging systems. This enables a wide range of applications, from large industrial vehicles to compact medical devices.

Realtime Robotics

Grant in 2018
Realtime Robotics, Inc. is focused on developing advanced motion planning and control processors that enable robots and autonomous vehicles to react instantaneously to their surroundings. Founded in 2016 and based in Boston, Massachusetts, the company offers a collision-free motion planning platform that allows for safe operation of single or multiple robots in unstructured environments. Their specialized RapidPlan processor generates safe motion plans in microseconds, effectively eliminating the trade-off between speed and safety in automation. This innovative technology accommodates real-time changes in dynamic environments, enabling robots to navigate around both known static objects and other moving entities while performing various tasks. By addressing the limitations of traditional automation, Realtime Robotics is broadening the applications of robotics across industries and facilitating the adoption of autonomous vehicles.

Boston Materials

Grant in 2018
Boston Materials, Inc. is a manufacturer of advanced composite materials, specializing in 3D reinforced carbon fiber pre-pregs. Founded in 2016 and based in Bedford, Massachusetts, the company utilizes patented Z-axis Fiber technology, which incorporates vertically aligned carbon fibers to enhance energy transfer properties. Its product line includes Carbon Supercomposite, a magnetically assembled carbon fiber pre-preg, which finds applications across various sectors such as aerospace, automotive, marine, wind energy, and sports equipment. Boston Materials' advanced materials aim to improve thermal, electrical, and mechanical properties, offering a roll-to-roll manufacturing process with in-line quality control and an annual production capacity of one million square meters. These innovations enable industries like semiconductors and electrified vehicles to achieve greater efficiency, reliability, and weight reduction while addressing critical challenges in durability and performance.

Ernest Pharmaceuticals

Grant in 2018
Ernest Pharmaceuticals is a biotechnology company that develops cancer-killing bacteria. The company was founded in 2016 and is headquartered in Hadley, Massachusetts.

Norwich University

Grant in 2018
Norwich University, a small New England college located in Northfield, Vermont, is the home of the ROTC and offers the full range of academic and professional programs to cadets and others. The ROTC program, which trains cadets, is one of Norwich’s more noteworthy academic offerings. However, non-cadets also attend to take advantage of undergraduate liberal arts and science degrees as well as professional majors in Architecture, Computer Science, Engineering, Pre-Law and Pre-Medicine. Graduate degrees at Norwich are delivered through online study. Online master’s degrees are awarded in such fields as Diplomacy, Education, Military History, Civil Engineering, Public Administration and Nursing. Based in the experiential learning model, Norwich’s curriculum uses a combination of experiential and theoretical techniques, a highly effective strategy for long-term integration of knowledge. Since it is an ROTC-friendly school, there are several benefits financially and otherwise for current and former military. Other financial aid options include loans, grants and scholarships for those who qualify. Applicants will need to submit an application, a personal statement, a transcript, and test scores to the admissions department. Letters of recommendation are also strongly suggested.

KnipBio

Series B in 2018
KnipBio is a biotechnology company that develops responsible and sustainable commercial feed solutions for the aquaculture industry. It is committed to solving real-world challenges by working with global corporations. Its game-changing single-cell protein combines the attributes of premium, protein-packed fishmeal, and carotenoids into a single effective and affordable fishmeal replacement -- KnipBio Meal (KBM). KBM is a transformative breakthrough in the future of aquaculture feed. It was founded in 2013 and is based in Lowell, Massachusetts.

Tunxis Community College

Grant in 2018
In the Farmington, Connecticut area, Tunxis Community College has academic, workforce training, and personal enrichment courses for students with all sorts of different interests that can earn you an associate’s degree or certificate. Among the many majors to choose from are programs such as Allied Health, Graphic Design, Visual Fine Arts, Business Office Technology, Computer Information Systems, Criminal Justice, Drug and Alcohol Recovery Counselor, Early Childhood Education, Engineering Science and Technology Studies, and New Media Communication, as well as many more. Counselors in the financial aid office can point you toward programs that will help you earn loans, grants, scholarships, veteran’s benefits, and more if you qualify. These financial aid options can help you pay for tuition and other expenses. Student life at TCC includes a student lounge, The Cyber Café, and the Barnes-Franklin Gallery, which is filled with student, community, and professional art. Academic advising is available for any student who needs help. The career center can help students find employment. Other student resources includes child care, health care, media center, and student activities.

Central Connecticut State University

Grant in 2018
Central Connecticut State University is a public institution located in New Britain, Connecticut, offering a wide range of academic degrees and recreational opportunities. Students can earn a bachelor’s degree from a wide range of traditional disciplines, while graduate degrees are available in an almost equally long list of concentrations. Most graduate programs offer a master’s degree, while only Education is offered as a doctorate degree. Student life is a vibrant campus escape from the classroom. Students are drawn to the many student organizations, student government opportunities, residential life, campus activities, athletic teams, and outdoor recreational excursions and activities. Student support services are provided to help students focus on their academic and recreational college life. Students are encouraged to take advantage of the student center, academic advising, the women’s center, the health clinic, academic workshops, career center, and much more. The faculty at Central Connecticut is expected to make themselves available for personal instruction and student questions on a weekly basis. Students should never feel like they are without assistance inside and out of the classroom. Central Connecticut State University is committed to supporting the academic pursuits of all students on its campus.

Manchester Community College

Grant in 2018
As the largest and one of Connecticut’s oldest community colleges, Manchester Community College has a long tradition of academic excellence. The school offers more than 40 certificate programs and over 50 associate’s degree programs, as well as non-credit courses for professional development and personal enrichment. Moreover, MCC’s academics are as unique as they are plentiful. There are a number of programs of study that you’d be hard pressed to find elsewhere. Homeland Security, Computer Game Design, and Drug & Alcohol Recovery Counseling are just a few of the forward-thinking academic programs available at Manchester Community College. One of MCC’s goals is to make education universally accessible, so the school makes financial aid abundantly available to eligible students. In addition to state and federal grants, Manchester Community College funds a number of academic and need-based scholarships. Students that feel unprepared for postsecondary study can participate in the Summer Training and Academic Retention Service (STARS) program. STARS is a six-week summer intensive designed for incoming freshmen, in which you’ll learn key skills for college and work with peer advisors to prepare yourself for the postsecondary experience. This program is open to anyone who qualifies for financial aid or is a first-generation college student. Best of all, it’s completely free!

Anfiro

Grant in 2018
Anfiro, Inc. is a water technology start-up based in Cambridge, Massachusetts, founded in 2014. The company specializes in developing advanced reverse osmosis polymer membranes that are both chlorine resistant and exhibit high permeability. By utilizing self-assembling polymers, Anfiro's membranes significantly outperform traditional technologies, leading to reduced costs for desalinating and purifying water. This innovative approach not only enhances efficiency in water treatment processes but also aims to address global freshwater scarcity by making clean and affordable water more accessible. Through its cutting-edge membrane technology, Anfiro seeks to contribute to sustainable water solutions for a better future.

GelSight

Grant in 2017
GelSight, Inc. specializes in advanced sensor technology solutions for precise surface measurements. The company has developed the GelSight benchtop scanner, which captures the surface geometry of various materials and accurately measures rigid objects across a wide range of scales. Their innovative technology allows for detailed three-dimensional visualization and measurement, revealing features that are not discernible to the naked eye, and providing dimensional accuracy to single-digit microns. GelSight's products are utilized in diverse sectors, including aerospace, electronics, and forensics, as well as in academic and research environments. Founded in 2011 and headquartered in Waltham, Massachusetts, GelSight continues to enhance its offerings while addressing the evolving surface measurement needs of its clients.

Neurable

Grant in 2017
Neurable Inc. is a neurotechnology company based in Cambridge, Massachusetts, founded in 2016. The company focuses on developing artificial intelligence software that translates brain activity into actionable insights, allowing users to control software and devices solely with their thoughts. Neurable's technology facilitates various applications, including gaming, operating toys, and driving vehicles, as well as enhancing experiences in virtual and augmented reality. By leveraging patented signal processing methods and a multidisciplinary approach that combines neuroscience, biology, statistics, and machine learning, Neurable aims to create high-performance brain-computer interfaces that are accessible and user-friendly.

QSM Diagnostics

Grant in 2017
QSM Diagnostics, Inc. is a Boston-based company founded in 2014 as a spin-off from the Goluch Group at Northeastern University. The company specializes in the development and manufacture of point-of-care diagnostics for the rapid identification of bacterial infections, particularly focusing on ear infections caused by Pseudomonas aeruginosa in dogs. QSM Diagnostics offers testing kits that utilize single-use disposable sensor technology to detect target molecules at the wound site. This innovation aids veterinarians and physicians in enhancing their diagnostic accuracy and treatment plans, ultimately improving animal care. With decades of experience in medical device development, QSM Diagnostics is committed to advancing veterinary diagnostics through its electrochemical sensors and medical devices.

Perceptive Automata

Grant in 2017
Perceptive Automata, Inc. specializes in developing machine learning and computer vision solutions focused on human behavior prediction for automated vehicles. Founded in 2014 and based in Somerville, Massachusetts, the company addresses critical challenges in the safe deployment of highly automated and fully autonomous vehicles, particularly in urban settings. Its technology enables these vehicles to anticipate the actions of pedestrians, cyclists, and other drivers, allowing for safe navigation in human-dominated environments. By employing advanced AI inference models, Perceptive Automata enhances the driving experience, facilitating smoother and more natural interactions between autonomous vehicles and their surroundings. The company collaborates with original equipment manufacturers (OEMs), suppliers, and technology firms in the development of advanced driver-assistance systems (ADAS) and autonomous driving technologies, leveraging expertise from leading institutions such as Harvard, MIT, and Stanford.

Artaic

Grant in 2017
Artaic, LLC is a Boston-based company that specializes in designing and fabricating custom tile work for both commercial and residential markets. Founded in 2007 by Ted Acworth, Artaic focuses on innovative mosaics that enhance the architecture and interior design sectors. Utilizing advanced technology, including computer-aided design software and a robotic mosaic assembly system, the company offers a wide range of applications, such as bathroom backsplashes, flooring, and public art installations. Artaic's approach allows for complete control over the color, material, and layout of its mosaics, enabling clients to achieve customized designs while minimizing costs. Additionally, the company provides installation services, further streamlining the process for its clientele.

Flexcompute

Grant in 2017
FlexCompute is an IT company based in Boston, Massachusetts, established in 2016. It specializes in advanced computer simulation technology aimed at accelerating research and development in computing. The company develops proprietary R&D solvers that enhance innovation and efficiency, particularly for clients in the quantum computing sector. By providing simulation schemes that facilitate the design of complex quantum circuits, FlexCompute enables its clients to shorten calculation times and drive advancements in their technological pursuits.

Manus Bio

Grant in 2017
Manus Bio Inc. specializes in recreating plant processes within microorganisms to produce natural ingredients through advanced fermentation technology. Founded in 2011 and based in Cambridge, Massachusetts, the company focuses on converting sugar sources into a variety of applications, including flavors, fragrances, food ingredients, cosmetics, vitamins, pharmaceuticals, and agricultural chemicals. By integrating metabolic engineering, protein engineering, and systems biology, Manus Bio develops microbes that efficiently manufacture complex and bioactive natural products. The company operates manufacturing facilities in Cambridge and Augusta, Georgia, and has established a strategic partnership with BBGI Public Company Limited. Formerly known as Manus Biosynthesis, Inc., the company adopted its current name in June 2018.

Inkbit

Grant in 2017
Inkbit Corporation, founded in 2017 and based in Medford, Massachusetts, specializes in the research, development, and manufacturing of 3D printers. The company has developed an advanced additive manufacturing platform that integrates 3D printing with machine vision technology, allowing for the rapid production of polymer parts. By employing machine learning and artificial intelligence, Inkbit delivers a multi-material jetting platform that meets the speed and precision required for demanding industrial applications. The expertise of its team, comprised of MIT-trained scientists and engineers, spans industrial systems, design software, and material science, enabling Inkbit to bridge the gap between prototyping and large-scale manufacturing. This innovation facilitates the on-demand production of both multi-material and end-use products, positioning Inkbit as a leader in the mass-market additive manufacturing sector.

Sober Grid

Grant in 2017
Sober Grid, Inc. operates a digital health platform that serves as a sober social network, facilitating connections among individuals recovering from substance use disorders. Launched in 2015 and headquartered in Boston, Massachusetts, the application is available on both Apple and Android devices and has been utilized over 20 million times across more than 170 countries. Developed in collaboration with researchers from Harvard Medical School and the University of Pennsylvania, Sober Grid employs a community-based approach to chronic disease management, incorporating evidence-based recovery tools and predictive analytics to assess relapse risk. The app features a GPS locator for users to find nearby sober individuals, along with direct messaging, a newsfeed, and access to certified coaching available 24/7. By combining technology with human connection, Sober Grid aims to improve health outcomes through real-time support and engagement, catering to a growing population of individuals in recovery.

Ras Labs

Grant in 2017
Ras Labs produces Synthetic Muscle electroactive polymer-based materials and actuators that contract and expand at low voltages. The company is driven by its mission is developing capabilities to improve the interface between mechanical devices and humans, particularly for prosthetics, rehabilitative robotics, and protective devices. It was founded in 2003 and headquartered in Quincy, Massachusetts.

Packetized Energy

Grant in 2017
Packetized Energy Technologies, Inc. is focused on enhancing the integration of distributed energy resources into the power grid. The company develops systems that enable appliances such as water heaters, electric vehicle chargers, and battery storage to balance energy supply and demand. Its flagship product, Packetized Energy Management (PEM), coordinates connected devices to optimize energy usage, ensuring real-time alignment with renewable energy supply. This platform provides local decision-making, privacy for users, and equitable access to grid resources, catering primarily to utilities, solar developers, and energy providers. By utilizing advanced control systems, machine learning, and optimization techniques, Packetized Energy aims to simplify grid edge flexibility and support the transition to a renewable energy future. Founded in 2016 and based in Colchester, Vermont, the company seeks to create value for both consumers and the electricity industry through its innovative approach to energy management.

Nanoview Biosciences

Grant in 2017
NanoView Biosciences is a biotechnology company that specializes in the development of technologies for the characterization of extracellular vesicles, particularly exosomes. Founded in 2015 and based in Boston, Massachusetts, the company utilizes its proprietary ExoView technology to provide high-throughput and cost-effective analysis solutions for life science researchers. NanoView's products, which include the ExoView R100 and ExoView tetraspanin, enable precise detection and multiparametric characterization of exosomes from complex biological samples such as blood, serum, plasma, and urine. In addition to its core products, the company offers custom assays, sample services, and a support platform to aid researchers in understanding the biological roles of exosomes and utilizing them as biomarkers for disease diagnosis, treatment, and monitoring.

Solchroma Technologies

Grant in 2017
Solchroma Technologies, Inc. specializes in manufacturing innovative digital display screens designed for advertising applications. Founded in 2015 and headquartered in Somerville, Massachusetts, the company offers non-LED displays characterized by sunlight reflectivity and print-quality color properties. These displays are particularly suited for outdoor advertising and on-premise signage, providing a low-power alternative to traditional light-emitting technologies. Solchroma's proprietary system utilizes electroactive polymer actuators that function as hydraulic pumps to move colored ink from reservoirs into viewable color filter chambers, allowing for full-color reflective displays. This technology enables compliance with zoning regulations that restrict emissive signage, making it an environmentally friendly option for urban settings.

DropWise Technologies

Grant in 2017
DropWise Technologies Corp. specializes in manufacturing advanced coating materials aimed at reducing carbon emissions in power plants and enhancing the efficiency of thermal systems. The company utilizes a unique vapor-based deposition process, developed in collaboration with leading MIT labs, to create ultra-thin, durable coatings that effectively address fouling and corrosion in heat exchange equipment. These coatings are significantly thinner than conventional options, allowing for improved heat transfer and reducing the need for excessive coolant water. DropWise's technology is applicable across various sectors, including power generation, desalination, HVAC/R, and chemical refining. By chemically grafting coatings to surfaces with precision, DropWise enhances the performance of critical components such as heat exchangers, ultimately enabling operators to maintain higher efficiency and durability while minimizing operational costs. Established in 2014 and based in Cambridge, Massachusetts, DropWise Technologies is poised to transform traditional coating solutions and access markets previously deemed unattainable.

CueThink

Grant in 2017
CueThink Inc. is a Boston-based company that provides a peer-to-peer mobile learning platform aimed at enhancing math problem-solving skills for students in grades 4-12. Founded in 2012 and incubated by PayPal, CueThink's platform allows students to develop systematic problem-solving abilities, improve their math language, and engage in collaborative learning by sharing strategies with peers. Teachers benefit from analytics on student growth and can align their instruction with Common Core standards, while parents can monitor their children's progress through portfolios showcasing strategies and feedback. The company's offerings include Quantum, an iPad application designed for grades 4-8, which supports the growing trend of one-to-one technology in classrooms. CueThink's innovative approach addresses the need for deeper learning in mathematics, leveraging students' familiarity with social media and gaming to create an engaging educational experience. The development of its platform was supported by a grant from the National Science Foundation, and it has been successfully piloted in various classrooms.
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