National Science Foundation

Landmark College in southern Vermont is one of the only accredited schools nationwide that provides innovative techniques and programs for students with learning disabilities such as dyslexia and attention deficit hyperactivity disorder (ADHD). Landmark College offers associate’s degrees in areas like business, general studies, and liberal arts. The school has summer courses to help high school graduates transition to institutions for higher learning, and to assist college students in getting ahead on their academic degree credits. In addition, Landmark provides study abroad programs to Europe, South America, and more for those who are eligible. This is a great option for students who want to see the world and obtain college credit. If financial aid is an area of interest, the school offers assistance in the form of grants, loans and scholarships to those who qualify. The college is located in a close-knit community with lots to offer, and there are on-campus and off-campus resources available for students. Between athletics, social and recreational activities, and outdoor adventures, the school has many opportunities. If you are looking for that type of environment and experience, you might want to find out more about Landmark College.

Dynocardia is a biomedical device company developing wearable, non-invasive blood pressure monitoring technology. Its ViTrack wrist-wearable device provides direct, beat-by-beat measurement of blood pressure and tracks heart rate, respiration, and rhythm with accuracy comparable to intra-arterial lines. The platform uses a wearable optomechanical sensor to enable continuous, mobile monitoring of cardiovascular parameters. Founded in 2018, the company is headquartered in Massachusetts and focuses on meeting critical clinical needs with portable monitoring solutions.

Vermont State University offers career-focused education accessible to students in Vermont and the region.

Norwich University is a nonprofit educational institution located in Northfield, Vermont, founded in 1819. It offers a diverse range of academic programs, including undergraduate degrees in liberal arts, sciences, and professional fields such as Architecture, Computer Science, Engineering, Pre-Law, and Pre-Medicine. The university is notable for its ROTC program, which trains cadets while also accommodating non-cadets who seek high-quality education. Graduate degrees are predominantly delivered online, with options available in Diplomacy, Education, Military History, Civil Engineering, Public Administration, and Nursing. Norwich employs an experiential learning model that integrates practical and theoretical approaches to education, enhancing knowledge retention. The university provides various financial aid opportunities, including loans, grants, and scholarships, particularly benefitting current and former military personnel. Admission requirements include submission of an application, a personal statement, transcripts, test scores, and letters of recommendation, which are strongly encouraged.

Worcester Polytechnic Institute (WPI), located in Worcester, Massachusetts, is a prestigious technological university founded in 1865. Renowned for its commitment to project-based learning, WPI emphasizes practical application of theoretical knowledge to address real-world challenges. The university boasts a distinguished faculty and state-of-the-art research facilities, fostering an environment rich in innovation and collaboration. WPI attracts ambitious students eager to engage in hands-on experiences that prepare them to make meaningful contributions to society. With a strong focus on developing skills that are crucial in today’s dynamic landscape, WPI positions itself as a leader in education and research, dedicated to empowering its students and faculty to achieve excellence.

Brightwater Tools, headquartered in Vermont, is a woman-led startup specializing in sustainable sanitation solutions. The company has developed a unique, building-scale wastewater nutrient recovery system that transforms high-strength wastewater into natural, nutrient-rich fertilizer. This process not only reduces harmful algal blooms by minimizing nutrient discharge into waterways but also promotes a circular economy by recycling valuable resources. Brightwater Tools' system comprises three proprietary pieces of equipment, each facilitating key wastewater processes and available for individual or combined sale. The company aims to become a significant equipment provider in this industry, with a strong customer base expected as it completes prototype and beta testing.

Theromics Inc., founded in 2016, develops innovative cell therapies. It specializes in HeatSYNC Gel, a biopolymer thermal accelerant that enhances microwave and radiofrequency energy absorption during soft tissue ablation procedures. This gel amplifies heat movement, optimizes ablation zone shape, increases treatment area, and protects critical tissues.

Thiozen develops innovative hydrogen gas production technology aimed at reducing greenhouse gas emissions. Its proprietary chemical process converts hydrogen sulfide into hydrogen gas, enabling clients to bypass carbon emissions associated with natural gas-based hydrogen production and avoid the high costs of electrolysis.

Since 1878, Champlain College has provided career-focused education to students from its hilltop campus in Burlington, Vt. Champlain's distinctive educational approach embodies the notion that true learning only occurs when information and experience come together to create knowledge. Champlain offers traditional undergraduate and online undergraduate courses, along with online certificate and degree programs and eight master's degree programs. Champlain offers study abroad programs at its campuses in Montreal, Quebec and Dublin, Ireland. Champlain College is included in the Princeton Review's “The Best 376 Colleges: 2012 Edition.” Champlain was named a "Top-Up-and-Coming School" by U.S. News & World Report's America's Best Colleges and is ranked in the top tier of 2012 Regional Colleges in the North

The Engine is an incubator and venture platform founded by MIT in Cambridge, Massachusetts, launched in 2016. It provides startups with space, streamlined legalities, access to lab space and equipment, and connects to patient capital from investors who share a long-term vision. The Engine offers business planning guidance, enabling startups to move from concept to market quickly. It supports up to 60 locally based startups concurrently through a 12-month accelerator, taking less equity than typical programs to help founders retain control. It connects to MIT resources via the Engine Room, providing resources and expertise. It targets Tough Tech areas such as artificial intelligence, climate and energy, autonomous systems, robotics, biotech and life sciences, and advanced manufacturing, combining science, engineering, and leadership to accelerate path to market and impact.

Rapid7, established in 2000, is a cybersecurity company that offers a range of solutions to help organizations proactively manage their security. Initially focusing on vulnerability management, the company has since expanded its portfolio to include detection and response, security information and event management, cloud security, threat intelligence, application security, and security orchestration, automation, and response. Rapid7 empowers businesses with visibility and insights to make informed security decisions, create action plans, and monitor progress. The company, based in Boston, is committed to helping organizations enhance their security posture and is actively involved in the cybersecurity community.

Remedium Bio is a Boston-based gene therapy company dedicated to developing curative treatments for a variety of debilitating conditions. The company employs a unique approach that combines established technologies in innovative ways to address well-defined disease mechanisms. By modularly applying these proven technologies, Remedium Bio focuses on creating localized and targeted therapies centered on clinically validated molecules and pathways. Its pipeline includes leading gene therapy candidates in multiple fields, such as rheumatology, endocrinology, and neurology, aimed at providing effective treatments for a range of immune, age-related, and metabolic disorders.

Quantivly, Inc., established in 2019 and headquartered in Somerville, Massachusetts, specializes in developing artificial intelligence-based solutions tailored for the field of radiology. The company focuses on enhancing data liquidity and providing analytical tools that enable radiology providers to make informed decisions, thereby increasing access to medical imaging services. Quantivly's platform is designed to manage and analyze MRI imaging workflows by cleaning and harmonizing scanner data, resulting in a vendor-neutral and comprehensive source of operational knowledge. This innovative approach supports radiology departments and imaging centers in utilizing data analytics to improve decision-making, facilitate new research initiatives, and enhance the overall patient experience in healthcare.

The University of Massachusetts Amherst is a public research and land-grant university that offers undergraduate, master's, and doctoral programs. It serves as the flagship campus of the University of Massachusetts system. The university has multiple academic departments and research facilities that support a range of disciplines.

Rich Earth Institute, founded in 2012 and based in Brattleboro, Vermont, focuses on advancing the utilization of human waste as a valuable resource through research, education, and technological development. The organization specializes in the design and manufacture of portable toilets that collect urine, facilitating a clean and sustainable approach to waste management. Its innovative platform enables the diversion, collection, treatment, and application of urine within community-scale recycling programs. This process not only promotes environmental sanitation but also encourages communities to repurpose human waste for agricultural applications, thus contributing to sustainable farming practices.

Brightwater Tools, headquartered in Vermont, is a woman-led startup specializing in sustainable sanitation solutions. The company has developed a unique, building-scale wastewater nutrient recovery system that transforms high-strength wastewater into natural, nutrient-rich fertilizer. This process not only reduces harmful algal blooms by minimizing nutrient discharge into waterways but also promotes a circular economy by recycling valuable resources. Brightwater Tools' system comprises three proprietary pieces of equipment, each facilitating key wastewater processes and available for individual or combined sale. The company aims to become a significant equipment provider in this industry, with a strong customer base expected as it completes prototype and beta testing.

QSimulate is a Boston-based company that specializes in developing cloud-based quantitative simulation tools focused on quantum molecular simulations. By leveraging the principles of quantum mechanics, QSimulate aims to address significant industrial-scale challenges primarily within the chemical and pharmaceutical sectors. Its innovative platform automates various workflows, allowing computational scientists to shift their focus from repetitive tasks to more strategic activities, ultimately enhancing productivity. This approach enables clients to accelerate their research and development processes, positioning QSimulate as a key player in advancing scientific inquiry and innovation in these industries.

Singularity Energy, Inc. is a technology company focused on developing a platform for real-time carbon tracking and energy optimization. Founded in 2018 and headquartered in Cambridge, Massachusetts, the company utilizes artificial intelligence to integrate real-time carbon dioxide signals from the energy grid into its solutions. This enables corporate clients, including climate regulators and sustainability directors, to visualize and co-optimize their energy usage and carbon emissions effectively. Singularity Energy's innovative approach combines data analytics with carbon forecasting and optimization algorithms, allowing organizations to minimize their emissions while maximizing economic benefits. The company's mission is to support entities in achieving their sustainability goals with transparency and confidence.

Maine Shellfish Developers is a sustainable aquaculture company specializing in the production of oysters. They offer oyster seedlings and mature oysters, along with other related seafood products.

Belmont Scientific is a chemical and battery safety technology company that specializes in process safety and risk management. The company was founded in 2011 and is based in Lowell, Massachusetts.

RaySecur Inc. is a company based in Cambridge, Massachusetts, focused on developing advanced 3D package scanning and imaging devices for detecting concealed threats in mail and parcels. Founded in 2018, RaySecur's MailSecur systems utilize millimeter-wave technology to provide real-time, three-dimensional imaging, which allows for the detection of powders, solids, liquids, and hazardous materials such as chemical, biological, radiological, and explosive composites. Unlike traditional X-ray systems, RaySecur's solutions are user-friendly, portable, and do not require extensive training for effective operation, making them suitable for various environments, including small mailrooms. The company’s technology is employed by Fortune 500 companies and government organizations worldwide to enhance security and protect personnel and assets from potential threats.

Lura Health develops a non-invasive continuous health monitoring platform that uses saliva as a diagnostic fluid. The company integrates micro-sensors into orthodontic devices such as retainers, aligners, and brackets to continuously measure saliva analytes and securely transmit data to a smartphone app, enabling users to monitor oral health metrics and potentially support broader chronic disease management. Target markets include heart disease, chronic kidney disease, diabetes, and tooth decay. Founded in 2017, the company is based in Cambridge, Massachusetts.

Dynocardia is a biomedical device company developing wearable, non-invasive blood pressure monitoring technology. Its ViTrack wrist-wearable device provides direct, beat-by-beat measurement of blood pressure and tracks heart rate, respiration, and rhythm with accuracy comparable to intra-arterial lines. The platform uses a wearable optomechanical sensor to enable continuous, mobile monitoring of cardiovascular parameters. Founded in 2018, the company is headquartered in Massachusetts and focuses on meeting critical clinical needs with portable monitoring solutions.

Bactana Corporation develops a nutritional product platform aimed at enhancing microbiome health in livestock and other animals. Its core product, FPS-4, manipulates immunometabolism to boost productivity while promoting good health. Bactana serves cattle farmers primarily in Connecticut and New York, with headquarters in Farmington, Connecticut.

Founded in 2016, AM Batteries specializes in the manufacture of Li-ion batteries using solvent-free electrode technology. This innovative approach aims to enhance energy efficiency, enable faster charging, and reduce production costs.

Boston Geospatial provides ready‑to‑use geospatial intelligence for operators and risk managers in critical infrastructure. Its platform identifies, measures, and manages exposure to natural threats by monitoring how the planet changes daily. Using curated datasets, it offers risk screening, real‑time alerts, and monitoring tools that help owners and operators evaluate asset exposure, prioritize response, inspections, and compliance activities, thereby improving safety and outcomes in a changing threat landscape.

Alloy Enterprises is a Somerville, Massachusetts-based developer of 3D printing technologies and industrial-engineered products aimed at reducing inefficiencies in conventional manufacturing. The company has developed an aluminum additive technology that enables dense, low-cost parts without relying on expensive or hazardous powders, addressing limitations in traditional methods and supporting advances in lightweight components and emissions reduction.

Thiozen develops innovative hydrogen gas production technology aimed at reducing greenhouse gas emissions. Its proprietary chemical process converts hydrogen sulfide into hydrogen gas, enabling clients to bypass carbon emissions associated with natural gas-based hydrogen production and avoid the high costs of electrolysis.

Chibitronics is a company that specializes in the creation of circuit stickers, which integrate technology and art through an innovative approach to electronics. Founded from Jie Qi's PhD research at the MIT Media Lab, Chibitronics produces peel-and-stick electronics that allow users to engage in circuit building and programming in a creative manner. The company offers toolkits that combine conductive circuit stickers, coin cell batteries, and adhesive copper tape, enabling artists, crafters, tinkerers, and students to design their own expressive electronics. Through its products, Chibitronics aims to democratize technology creation, making it accessible and enjoyable for individuals interested in exploring the intersection of art and circuitry.

Biko Biolabs is a research company founded in 2020 in Somerville, Massachusetts, that explores the intersection of plastic waste and regenerative agriculture. The organization develops biodegradable alternatives to non‑recyclable plastics, investigates the environmental impact of microplastics, and employs fungi‑based processes to upcycle textile waste. Its work supports circular economy practices and seeks to enhance sustainability and self‑sufficiency for traditionally marginalized communities.

Skyhaven Systems is a specialty research and development firm based in Steamboat Springs, Colorado, with primary research and development facilities located in Westford, Massachusetts. Founded in 2017 through the merger of Reactive Innovations, LLC, the company focuses on addressing critical needs in the Defense, Energy, Aerospace, and Environmental sectors for various U.S. government agencies, including the Department of Defense and NASA. Skyhaven applies advanced electrochemical engineering and reaction-based chemical processes to tackle complex technical challenges, conducting innovative work in areas such as reactor design, separation systems, and materials development. The firm operates a 4,200 square foot facility for research, development, and light manufacturing, and it pursues government-funded contracts to explore high-risk development areas. By retaining ownership of the technology rights generated from these projects, Skyhaven can commercialize its innovations for non-government applications while providing the government with a royalty-free license to use the technologies developed. This approach positions Skyhaven as a key player in creating sustainable solutions that enhance performance and reduce costs across various industries.

MedChem Partners is a medicinal chemistry CRO that specializes in developing small molecule therapeutics. The company was founded in 2006 and is headquartered in Lexington, Massachusetts.

Theromics Inc., founded in 2016, develops innovative cell therapies. It specializes in HeatSYNC Gel, a biopolymer thermal accelerant that enhances microwave and radiofrequency energy absorption during soft tissue ablation procedures. This gel amplifies heat movement, optimizes ablation zone shape, increases treatment area, and protects critical tissues.

Founded in 2020, Stellate DNA specializes in developing proprietary DNA donor technology for synthesizing and producing single-strand DNA donors. Headquartered in Cambridge, Massachusetts.

Simpact is a Boston-based company that specializes in developing analytics and forecasting software designed to aid businesses in making informed, data-driven decisions. The software utilizes computer simulations to model target social systems, allowing clients to evaluate risks related to influencers, trends, and interventions. By doing so, Simpact enables organizations to effectively forecast the outcomes of various allocations of their limited resources, ultimately enhancing their strategic planning and decision-making processes.

Xheme is a technology company founded in 2019 and based in Newton, Massachusetts, that specializes in developing advanced blood bag technology aimed at extending the shelf life of blood and platelets. The company also focuses on creating specialty chemicals designed to enhance product quality, sustainability, and safety across various industrial sectors. Xheme's innovative products are programmable, allowing them to provide multiple protective functions such as resistance to oxidation, ultraviolet light, corrosion, and microbial threats. This versatility enables industries to preserve the aesthetic and functional quality of their products over extended periods.

Heila Technologies, Inc. is a Massachusetts-based company that specializes in the development of a platform designed to integrate and optimize distributed energy resources (DERs) such as solar arrays and batteries. The Heila Platform employs a decentralized optimization system that simplifies the management of these resources, enabling the creation of self-managing microgrids. By transforming individual nodes within the energy system into intelligent agents, the platform facilitates autonomous coordination and optimization of power assets. This approach helps to reduce complexity and costs while enhancing resilience and efficiency in energy operations. Heila Technologies serves a diverse clientele, including partners, utility representatives, developers, energy users, and public officials. Originally founded as Heila Technologies LLC, the company was incorporated in 2015 and has its roots in MIT.

Founded in 2020, Irradiant Technologies specializes in developing advanced lithography techniques for high-throughput microfabrication. Headquartered in Cambridge, Massachusetts, the company's core technology enables ultrafast three-dimensional assembly of diverse materials with nanoscale precision, facilitating innovation in photonic and optical components for telecommunications, computation, and sensing.

FluidForm Bio is a biotechnology company focused on creating living human tissue to improve disease treatment. Utilizing its patented FRESH technology, the company employs 3D printing to construct tissue using cells, proteins, and no other materials. This innovative platform has been validated through partnerships with leading life science companies, enabling the production of high-quality tissue for various applications. FluidForm Bio's advanced techniques integrate breakthroughs in 3D printing, computational and synthetic biology, artificial intelligence, and materials science to deliver human tissue that closely resembles natural tissue. Established in 2018 and headquartered in Waltham, Massachusetts, FluidForm Bio aims to provide transformative therapies that offer better treatment options for patients in need.

Aliro Technologies, Inc. specializes in developing a cloud-based software-as-a-service platform designed for coding within quantum environments. Founded in 2019 and headquartered in Boston, Massachusetts, the company provides a hardware-independent toolkit aimed at developers of quantum algorithms and applications for quantum computers. Known as AliroNet™, this platform facilitates the emulation, piloting, and deployment of entanglement-based quantum networks, which can support a wide range of applications from secure communications to clustered quantum computing and distributed quantum sensing. With a foundation rooted in research from Harvard University, Aliro Technologies comprises experts in both quantum and classical networking, positioning itself as a leader in quantum network development. Its user base spans utility companies, telecommunications providers, public sector organizations, enterprises, and researchers engaged in building the first entanglement-based quantum networks. The company also collaborates with industry and academic partners through various consortiums and is actively involved in quantum networking standards groups.

SilarTek is a technology company established in 2020 and located in Leominster, Massachusetts. The company specializes in developing innovative solar silicon technology aimed at making solar panels more affordable and accessible to a broader audience. SilarTek's unique approach involves utilizing molten salt electrolysis combined with an advanced molten salt composition, which enables the production of low-cost solar-grade silicon. This technology is designed to benefit both consumers and businesses by providing an efficient solution for solar panel manufacturing.

Enable Therapeutics is a biotechnology company developing a patented drug delivery platform. The company was founded in 2020 and is headquartered in Hopedale, Massachusetts.

SiTration, founded in Cambridge, Massachusetts in 2020 by Brendan Smith, specializes in developing ultra-durable filtration membrane technology. This technology is designed to efficiently separate substances in harsh and challenging industrial environments while reducing energy consumption compared to conventional methods. The company's membranes combine the advantages of various state-of-the-art commercial membranes, offering users resource-efficient operations even in unpleasant industrial settings.

Spero Therapeutics is a clinical-stage biopharmaceutical company dedicated to developing novel treatments for multi-drug resistant bacterial infections and rare diseases. Its primary focus is on tebipenem pivoxil hydrobromide, an oral carbapenem-class antibiotic intended for adult use in treating MDR Gram-negative infections.

Junora LTD is a manufacturer based in Biddeford, Maine, specializing in the design and production of rotary and planar sputter targets for the thin film deposition industry. Founded in 2017, the company offers a diverse range of thin film deposition products, including rotary and planar targets, as well as target fabrication services, engineering and design, and precision machining. Junora's products are available in various materials such as aluminum, copper, indium, lithium, silver, tin, zinc, and custom alloys. The company aims to introduce new technologies and capabilities to the market, enabling clients to access a wide variety of sputtering products used in vacuum deposition processes across multiple industries.

GreenSight develops a commercial drone platform for autonomous data collection. Its full-stack product combines custom hardware, software, advanced sensors, and data analytics to provide actionable insights in agriculture, energy, construction, and infrastructure sectors. The company initially focused on the golf course industry, offering daily agricultural analytics services and labor management solutions.

Quantivly, Inc., established in 2019 and headquartered in Somerville, Massachusetts, specializes in developing artificial intelligence-based solutions tailored for the field of radiology. The company focuses on enhancing data liquidity and providing analytical tools that enable radiology providers to make informed decisions, thereby increasing access to medical imaging services. Quantivly's platform is designed to manage and analyze MRI imaging workflows by cleaning and harmonizing scanner data, resulting in a vendor-neutral and comprehensive source of operational knowledge. This innovative approach supports radiology departments and imaging centers in utilizing data analytics to improve decision-making, facilitate new research initiatives, and enhance the overall patient experience in healthcare.

Vaxess Technologies is a biotechnology company focused on silk biomaterial platforms for vaccine and therapeutic delivery. It develops the MIMIX microneedle patch for transdermal, sustained-release delivery of vaccines and therapies, designed to improve stability and ease of use, including formulations that do not require cold chain storage. The MATRIX formulation and drying platform supports thermostable vaccine, therapeutic, and diagnostic products. The company aims to enable long-term immune responses and easier distribution, including in low-resource settings. Its technology supports oncology and infectious disease applications, including therapies that promote durable anti-tumor immunity and improved treatment outcomes. Founded in 2011 and based in Boston, the company positions its platforms to enable stable, targeted delivery and potentially reduce treatment burden for patients.

Founded in 2016, Ernest Pharmaceuticals is a biotechnology company based in Hadley, Massachusetts. It specializes in developing cancer-killing bacteria using synthetic techniques to create motile, tumor-penetrating bacterial therapeutics for treating metastatic and inoperable tumors.

Thinking Robots is a Boston-based company founded in 2010 that specializes in developing software solutions for robotic tasks applicable across various robotic platforms. The company focuses on creating custom software that enhances robotic capabilities, integrating natural language dialogue, sensors, actuators, and high-level planning. This advanced architecture enables robots to interact with humans, transforming them into interactive and teachable entities that can be directly instructed by users. Through its innovative approach, Thinking Robots aims to facilitate the development of more responsive and user-friendly robotic systems.

Millimeter Wave Systems, founded in 2016 and headquartered in Amherst, Massachusetts, specializes in millimeter wave and microwave hardware solutions. The company develops a range of products, including subsystems, modules, components, and antennas, as well as advanced technologies such as cryogenic quantum-limited parametric amplifiers and latching junction ferrite circulators. These innovations are utilized in various applications, including medical scanners, sensors, automobile radars, and high data-rate communications. Millimeter Wave Systems aims to provide consistent quality in production while offering customizable solutions tailored to specific industry needs.

Worcester Polytechnic Institute (WPI), located in Worcester, Massachusetts, is a prestigious technological university founded in 1865. Renowned for its commitment to project-based learning, WPI emphasizes practical application of theoretical knowledge to address real-world challenges. The university boasts a distinguished faculty and state-of-the-art research facilities, fostering an environment rich in innovation and collaboration. WPI attracts ambitious students eager to engage in hands-on experiences that prepare them to make meaningful contributions to society. With a strong focus on developing skills that are crucial in today’s dynamic landscape, WPI positions itself as a leader in education and research, dedicated to empowering its students and faculty to achieve excellence.

Founded in 2008, this company specializes in manufacturing equipment for solar panel production. Its core technology, the floating silicon method, enhances wafer efficiency, reduces manufacturing costs and emissions.

Paramount Planet Product is an Orono-based startup focused on addressing ocean pollution through the development of environmentally friendly packaging solutions. The company specializes in manufacturing low-cost, compostable plant-based single-use packaging that mimics plastic in appearance but is designed to be safe for marine environments if discarded. By utilizing ocean compostable materials, Paramount Planet Product aims to enhance the performance of its packaging while minimizing environmental impact. The company is dedicated to improving ocean safety through rigorous testing and innovation, allowing customers to adopt packaging solutions that align with sustainable practices.

Full Circle Microbes provides a waste disposal service that converts organic waste into fertilizer. The company was founded in 2019 and is headquartered in Hinesburg, Vermont.

Armada Marine Robotics, headquartered in Falmouth, Massachusetts, specializes in developing asymmetric propulsion technology. This innovation enhances marine maneuverability by providing both thrust and steering from a single motor, enabling customers to create more efficient and agile underwater vehicles.

ActivSignal, established in 2016 and based in Natick, Massachusetts, specializes in biotechnology. The company focuses on developing innovative protein profiling technologies, primarily serving the proteomics research sector. Their tools enable scientists to analyze multiple signaling pathways simultaneously, providing insights into cellular pathway activation or inhibition profiles.

Travera, LLC is a biotechnology company based in Cambridge, Massachusetts, founded in 2017. It specializes in cancer therapy guidance through its innovative measurement technology, utilizing the Suspended Microchannel Resonator (SMR). This advanced device functions as an extremely sensitive scale that can detect minute changes in the weight of individual cancer cells, specifically measuring the Mass Accumulation Rate (MAR) biomarker. By identifying rapid weight changes in response to cancer drugs, Travera enables oncologists to make informed decisions about which therapies to prescribe, based on the actual responses of patients' tumor cells. The technology is designed to differentiate between natural cell death and drug-induced cell death, providing timely and accurate insights that are critical for effective cancer treatment.

CoreMap, Inc. is a medical technology company based in Winooski, Vermont, focused on developing advanced diagnostic solutions for electrophysiologists treating atrial fibrillation. Incorporated in 2016, the company offers a micro-electrode solution that allows for sequential mapping of tissue properties, addressing significant challenges in the treatment of atrial fibrillation, such as poor spatial resolution and inadequate sample density. Additionally, CoreMap's ultra-high resolution electrodes provide detailed insights into cardiac activation, even during episodes of fibrillation. By enhancing the diagnostic capabilities of electrophysiologists, CoreMap aims to improve patient outcomes in the management of this complex condition.

Lura Health develops a non-invasive continuous health monitoring platform that uses saliva as a diagnostic fluid. The company integrates micro-sensors into orthodontic devices such as retainers, aligners, and brackets to continuously measure saliva analytes and securely transmit data to a smartphone app, enabling users to monitor oral health metrics and potentially support broader chronic disease management. Target markets include heart disease, chronic kidney disease, diabetes, and tooth decay. Founded in 2017, the company is based in Cambridge, Massachusetts.

Metalmark Innovations, Inc. focuses on developing and delivering advanced 3D nanostructured coatings designed to treat airborne pollutants and toxins, enhancing indoor air quality. The company offers its innovative materials as additive coatings for various applications, including building materials and vehicle interiors, effectively addressing pollutants such as hydrocarbons, carbon monoxide, ozone, PM2.5, volatile organic compounds, odors, and germs. Its air cleaning technology employs catalytic materials that filter air with nanoscale precision, contributing to solutions for air pollution and climate change challenges. Founded in 2017 and headquartered in Boston, Massachusetts, Metalmark Innovations was previously known as Aircrew Technologies, Inc. before rebranding in January 2019.

Founded in 2017, Infinite Cooling specializes in wastewater management and recycling. It uses high-voltage electric fields to capture and recycle vast amounts of water that would otherwise be lost at industrial facilities like power plants, data centers, and factories.

Founded in 2017, Mizar Imaging specializes in developing modular light sheet illumination systems for high-resolution imaging. Headquartered in Woods Hole, Massachusetts, the company's innovative technology reduces photobleaching and enables physiologically relevant biological process imaging on modern inverted microscopes.

VeraMorph is a pharmaceutical company established in 2017 and based in Mansfield, Massachusetts. The company specializes in developing an innovative oral drug delivery technology that utilizes proprietary oral hydrogel tablets. This technology aims to enhance drug stability, achieve a rapid dissolution rate, and maintain prolonged high saturation levels in oral dosage forms. VeraMorph's approach allows for higher drug loading compared to traditional formulations, enabling pharmaceutical companies to improve product performance while also reducing the cost and time required to bring their products to market. Through its focus on contract manufacturing and formulation services, VeraMorph seeks to advance the efficiency of drug delivery systems in the pharmaceutical industry.

Founded in 2019, Ichosia Biotechnology is based in Worcester, Massachusetts. The company specializes in developing laboratory-produced red blood cells, aiming to harness natural genetic processes to create a consistent and compatible alternative to traditional donor blood.

Alloy Enterprises is a Somerville, Massachusetts-based developer of 3D printing technologies and industrial-engineered products aimed at reducing inefficiencies in conventional manufacturing. The company has developed an aluminum additive technology that enables dense, low-cost parts without relying on expensive or hazardous powders, addressing limitations in traditional methods and supporting advances in lightweight components and emissions reduction.

InThePendant is a technological platform founded in 2019 and headquartered in Lexington, Massachusetts. The company focuses on delivering meaningful insights through its innovative technology. By leveraging advanced data analysis and user-friendly interfaces, InThePendant aims to enhance decision-making processes for its clients.

Biocogniv develops AI-powered diagnostic tools for hospitals, delivering real-time clinical intelligence by integrating with electronic health records. Its platform analyzes standard blood tests and other data to screen patients for COVID-19 and to predict sepsis-related in-hospital mortality and ICU admission at emergency department presentations, enabling non-invasive, data-driven decision making. The solution plugs into existing EHR workflows to improve quality, lower costs, and expand access to care. The company was founded in 2019 and is based in Burlington, Vermont.

Neuright is a biotech company that develops theragnostic devices for peripheral neuropathy. The company was founded in 2018 and is headquartered in Orono, Maine.

Rich Earth Institute, founded in 2012 and based in Brattleboro, Vermont, focuses on advancing the utilization of human waste as a valuable resource through research, education, and technological development. The organization specializes in the design and manufacture of portable toilets that collect urine, facilitating a clean and sustainable approach to waste management. Its innovative platform enables the diversion, collection, treatment, and application of urine within community-scale recycling programs. This process not only promotes environmental sanitation but also encourages communities to repurpose human waste for agricultural applications, thus contributing to sustainable farming practices.

GelSight is a sensor technology company that develops advanced surface measurement solutions, including a benchtop GelSight scanner that captures the surface geometry of a wide range of materials. Its technology can visualize three-dimensional topography and provide micron-level dimensional measurements by digitizing tactile sensing on an elastomeric interface, enabling detailed measurements across four orders of magnitude. The company serves aerospace, electronics, universities, research institutions, and forensics applications, with prototypes and tools designed to reveal surface features invisible to the naked eye. Based in Waltham, Massachusetts, GelSight focuses on flexible metrology solutions for quality control, testing, and research, helping clients obtain reliable, high-resolution surface data for design, inspection, and material studies.

Brightwater Tools, headquartered in Vermont, is a woman-led startup specializing in sustainable sanitation solutions. The company has developed a unique, building-scale wastewater nutrient recovery system that transforms high-strength wastewater into natural, nutrient-rich fertilizer. This process not only reduces harmful algal blooms by minimizing nutrient discharge into waterways but also promotes a circular economy by recycling valuable resources. Brightwater Tools' system comprises three proprietary pieces of equipment, each facilitating key wastewater processes and available for individual or combined sale. The company aims to become a significant equipment provider in this industry, with a strong customer base expected as it completes prototype and beta testing.

Boston Materials designs and manufactures advanced composite materials, including carbon fiber pre-pregs enabled by its patented Z-axis Fiber technology, which uses vertically aligned carbon fibers to improve energy transfer. The company produces magnetically assembled carbon fiber pre-pregs and other specialty materials for semiconductors, aerospace platforms, and thermal management, delivering lightweight, high-performance solutions for electronics, aviation, electrified vehicles, and related industries. Its processes include roll-to-roll manufacturing with in-line quality control to support scalable production and consistent quality across applications.

Bitome is a Boston-based connected medical device company focused on developing innovative monitoring solutions. Founded two years ago, it has created a noninvasive tool for assessing hydration status, which has significant applications in various fields, including dialysis, diabetes management, sports performance, and maternal/fetal health. The company's initial application targets patients with congestive heart failure (CHF), allowing for precise monitoring of volume status—an important yet challenging biometric to measure that is closely linked to patient outcomes. Bitome aims to revolutionize hydration monitoring in a manner comparable to the impact glucose monitoring has had on diabetes care.

Root AI, Inc. is a Woburn, Massachusetts-based company that develops artificial intelligence-powered robots specifically designed for indoor farming. Founded in 2018 by Joshua Lessing and Ryan Knopf, Root AI focuses on creating intelligent robotics that assist growers in building advanced agricultural systems. The company’s flagship product, the Virgo 1, is an autonomous robot capable of harvesting tomatoes without causing bruising and is equipped with advanced vision systems to better assess ripeness than human workers. Root AI aims to enhance efficiency in indoor farming, enabling growers to produce high-quality, chemical-free produce while optimizing operational processes.

Quisigamond Community College, located in Worcester, MA, serves over 13,000 students and offers more than 70 associate degree and certificate programs. In addition to the traditional student academic program, Quisigamond offers online classes specifically geared toward working students or professionals who want to enhance their skills or build new ones. Those classes include Business Administration, Fire Science, Criminal Justice, Computer Science and Hospitality Management. Certificates are available in business administration/insurance or medical office options, Hotel and Restaurant Management, Early Childhood Education, and Law Enforcement. Various healthcare certificates are also offered including Surgery Technology, basic Paramedic and Dental Assisting. Associate Degrees are offered in Deaf Studies, Biomedical Engineering, Electromechanical Technology, Telecommunications Technology and Energy Utility. Quisigamond has developed outstanding relationships with potential employers in the central Massachusetts area including Intel, Verizon, Kennedy Diecasting, UPS and Ken-Weld and sponsors regular collaborations for workforce training. The Children’s School is available for enrolled students and members of the community with children between the ages of 2 to 5 years and also operates as a training center for Early Childhood Education students . The Division of Continuing Education hosts non-credit courses, workshops and seminars that are widely attended by the community and students.

JuliaHub is a platform empowering scientists, engineers, and innovators with high-performance computing capabilities. It enables discovery, building, and sharing of packages, along with effortless parallel computing.

Singularity Energy, Inc. is a technology company focused on developing a platform for real-time carbon tracking and energy optimization. Founded in 2018 and headquartered in Cambridge, Massachusetts, the company utilizes artificial intelligence to integrate real-time carbon dioxide signals from the energy grid into its solutions. This enables corporate clients, including climate regulators and sustainability directors, to visualize and co-optimize their energy usage and carbon emissions effectively. Singularity Energy's innovative approach combines data analytics with carbon forecasting and optimization algorithms, allowing organizations to minimize their emissions while maximizing economic benefits. The company's mission is to support entities in achieving their sustainability goals with transparency and confidence.

Worcester Polytechnic Institute (WPI), located in Worcester, Massachusetts, is a prestigious technological university founded in 1865. Renowned for its commitment to project-based learning, WPI emphasizes practical application of theoretical knowledge to address real-world challenges. The university boasts a distinguished faculty and state-of-the-art research facilities, fostering an environment rich in innovation and collaboration. WPI attracts ambitious students eager to engage in hands-on experiences that prepare them to make meaningful contributions to society. With a strong focus on developing skills that are crucial in today’s dynamic landscape, WPI positions itself as a leader in education and research, dedicated to empowering its students and faculty to achieve excellence.

Belmont Scientific is a chemical and battery safety technology company that specializes in process safety and risk management. The company was founded in 2011 and is based in Lowell, Massachusetts.

RaySecur Inc. is a company based in Cambridge, Massachusetts, focused on developing advanced 3D package scanning and imaging devices for detecting concealed threats in mail and parcels. Founded in 2018, RaySecur's MailSecur systems utilize millimeter-wave technology to provide real-time, three-dimensional imaging, which allows for the detection of powders, solids, liquids, and hazardous materials such as chemical, biological, radiological, and explosive composites. Unlike traditional X-ray systems, RaySecur's solutions are user-friendly, portable, and do not require extensive training for effective operation, making them suitable for various environments, including small mailrooms. The company’s technology is employed by Fortune 500 companies and government organizations worldwide to enhance security and protect personnel and assets from potential threats.

Ras Labs, LLC is a company that specializes in the development and production of Synthetic Muscle, a polymer-based material that mimics natural muscle movement through expansion and contraction in response to electric impulses. Founded in 2003 and headquartered in Quincy, Massachusetts, Ras Labs focuses on enhancing the interface between mechanical devices and humans. Its innovations are particularly beneficial in the fields of prosthetics, rehabilitative robotics, and protective devices. The company also manufactures robotic arm products that incorporate material science and data engineering to achieve precise motion in automation processes. These products feature tactile sensors that enable soft gripping of fragile objects, improving touch detection and location sensing in robotic grippers. Ras Labs aims to facilitate gentle grasping and adaptive responses in robotic applications, promoting more intuitive interactions between humans and machines.

DeepHealth, Inc. is a radiology artificial intelligence and machine learning company based in Cambridge, Massachusetts, founded in 2015. The company specializes in developing solutions for the medical interpretation of mammography exams, leveraging machine learning to translate extensive insights from medical experts into software that supports radiologists. DeepHealth aims to enhance patient care by creating reliable products grounded in rigorous science and clinical integration, ultimately assisting clinicians in making informed decisions.

Boston Children's Museum, founded in 1913 by the Science Teachers' Bureau, is the second oldest and one of the most influential children's museums globally. Located in Boston, Massachusetts, it operates as an independent non-profit organization dedicated to promoting the healthy development of all children. The museum engages young visitors through interactive exhibits and joyful discovery experiences that foster an appreciation for their world, develop essential skills, and inspire a lifelong love of learning. For over a century, it has served as a vital resource for teachers and families, contributing to the collective well-being and future prosperity of the community.

Founded in 1881, the University of Connecticut is a public research university located in Storrs, Connecticut. It offers a comprehensive range of academic programs through its various schools and colleges, with a focus on driving innovation and preparing students for successful careers.

Sober Grid, Inc. is a digital health company that operates a sober social network aimed at supporting individuals in recovery from substance use disorders. Incorporated in 2015 and based in Boston, Massachusetts, the company has developed a mobile application available on both iOS and Android platforms. The app allows users to connect with others who are also navigating sobriety, fostering a community where they can share experiences and challenges. Sober Grid's platform is utilized in over 170 countries and has been accessed more than 20 million times. It integrates features such as GPS locator interfaces, direct messaging, and educational resources, while also offering certified coaching services available 24/7. The app employs a unique community-based approach to chronic disease management, utilizing predictive analytics to anticipate relapse risks and provide timely interventions. Sober Grid's commitment to improving health outcomes is supported by research collaborations with esteemed institutions like Harvard Medical School and the University of Pennsylvania, demonstrating its effectiveness in reducing relapse rates among users.

Founded in 2017, Infinite Cooling specializes in wastewater management and recycling. It uses high-voltage electric fields to capture and recycle vast amounts of water that would otherwise be lost at industrial facilities like power plants, data centers, and factories.

Elephant Stem develops a video game platform to assist students in learning statistics. The company is based in Cambridge, Massachusetts.

Heila Technologies, Inc. is a Massachusetts-based company that specializes in the development of a platform designed to integrate and optimize distributed energy resources (DERs) such as solar arrays and batteries. The Heila Platform employs a decentralized optimization system that simplifies the management of these resources, enabling the creation of self-managing microgrids. By transforming individual nodes within the energy system into intelligent agents, the platform facilitates autonomous coordination and optimization of power assets. This approach helps to reduce complexity and costs while enhancing resilience and efficiency in energy operations. Heila Technologies serves a diverse clientele, including partners, utility representatives, developers, energy users, and public officials. Originally founded as Heila Technologies LLC, the company was incorporated in 2015 and has its roots in MIT.

Ecto, established in 2013 at Harvard Innovation Labs by Dmitry Kozachenok and James Webb, specializes in developing advanced technology that intersects data and biology to enhance aquaculture efficiency and sustainability globally. Headquartered in Boston with offices in Atlanta and Stavanger, Norway, the company collaborates with farmers worldwide, offering a farm management platform that integrates operational data with molecular biology. This enables real-time insights, disease detection, and prevention, ultimately streamlining production processes and creating healthier protein servings. To date, Ecto's solutions have facilitated an additional 51.5 million healthy servings of protein. The company has been backed by competitive research grants from the US National Science Foundation, US Department of Agriculture, and Innovation Norway.

AmberWave, Inc. is a research and development company specializing in photovoltaic technology solutions for commercial buildings, as well as semiconductor manufacturing technologies. Founded in 1998, the company has developed a range of advanced materials and technologies, including Strained Silicon, which enhances microchip performance while reducing power consumption, and Aspect Ratio Trapping, used for silicon-based photonics and photovoltaic applications. AmberWave aims to provide high-value products for underrepresented markets and new applications, focusing on substrate engineering for integrated circuits, semiconductor lighting, and photovoltaics. The company is headquartered in Salem, New Hampshire, and was previously known as AmberWave Systems Corporation before changing its name in 2010.

Boston Microtechnology is a semiconductor company that specializes in the development of CMOS-integrated isolated AC/DC conversion. The company was founded in 2014 and is based in Burlington, Massachusetts.

University of Massachusetts Lowell is a high-ranking university, with several nationally recognized academic departments. Located about 30 minutes from Boston in Lowell, Massachusetts, UMass Lowell offers more than 100 degree programs at the undergraduate and graduate levels. UMass Lowell has several nationally recognized, research-oriented programs, including science and engineering. These programs undertake groundbreaking research and also provide exceptional work opportunities for its students and graduates. Other programs at UMass Lowell include liberal and fine arts, humanities, health-related programs, teacher education and social sciences. UMass Lowell also offers a range of internship opportunities for students who wish to gain experience in their field of study. Student life options at UMass Lowell include more than 100 diverse student organizations, leadership programs and community service opportunities. Lowell’s admissions policies are moderately competitive. Financial aid is available to eligible students through loans, academic scholarships and other sources to help cover tuition.

Metalmark Innovations, Inc. focuses on developing and delivering advanced 3D nanostructured coatings designed to treat airborne pollutants and toxins, enhancing indoor air quality. The company offers its innovative materials as additive coatings for various applications, including building materials and vehicle interiors, effectively addressing pollutants such as hydrocarbons, carbon monoxide, ozone, PM2.5, volatile organic compounds, odors, and germs. Its air cleaning technology employs catalytic materials that filter air with nanoscale precision, contributing to solutions for air pollution and climate change challenges. Founded in 2017 and headquartered in Boston, Massachusetts, Metalmark Innovations was previously known as Aircrew Technologies, Inc. before rebranding in January 2019.

Travera, LLC is a biotechnology company based in Cambridge, Massachusetts, founded in 2017. It specializes in cancer therapy guidance through its innovative measurement technology, utilizing the Suspended Microchannel Resonator (SMR). This advanced device functions as an extremely sensitive scale that can detect minute changes in the weight of individual cancer cells, specifically measuring the Mass Accumulation Rate (MAR) biomarker. By identifying rapid weight changes in response to cancer drugs, Travera enables oncologists to make informed decisions about which therapies to prescribe, based on the actual responses of patients' tumor cells. The technology is designed to differentiate between natural cell death and drug-induced cell death, providing timely and accurate insights that are critical for effective cancer treatment.

Helios Applied Science develops ultra-portable innovations for first-response rescue and humanitarian relief. The company is based in Hyde Park, Massachusetts.

3Derm Systems, Inc., based in Boston, Massachusetts, is a pioneering company in 3D dermatology that provides a specialized handheld skin imager and cloud-based software designed for capturing, storing, and transmitting high-resolution 3D images of the skin. Established in 2011, the company enables non-dermatologists to take clinical-quality skin images remotely, facilitating efficient monitoring of skin lesions by dermatologists. This innovative approach reduces healthcare costs, shortens wait times, and enhances access to dermatological care, particularly for the two million Americans diagnosed with skin cancer annually. By allowing patients to capture images from the comfort of their homes and upload them for review, 3Derm helps prioritize in-office appointments for those with more concerning conditions. The company's technology aims to transform teledermatology, offering a cost-effective solution that maintains the continuity of care with local dermatologists while ensuring high diagnostic quality. As of August 2020, 3Derm operates as a subsidiary of Digital Diagnostics, Inc.

ActivSignal, established in 2016 and based in Natick, Massachusetts, specializes in biotechnology. The company focuses on developing innovative protein profiling technologies, primarily serving the proteomics research sector. Their tools enable scientists to analyze multiple signaling pathways simultaneously, providing insights into cellular pathway activation or inhibition profiles.

Millimeter Wave Systems, founded in 2016 and headquartered in Amherst, Massachusetts, specializes in millimeter wave and microwave hardware solutions. The company develops a range of products, including subsystems, modules, components, and antennas, as well as advanced technologies such as cryogenic quantum-limited parametric amplifiers and latching junction ferrite circulators. These innovations are utilized in various applications, including medical scanners, sensors, automobile radars, and high data-rate communications. Millimeter Wave Systems aims to provide consistent quality in production while offering customizable solutions tailored to specific industry needs.

Gel4Med LLC is a Boston-based medical technology company founded in 2015, specializing in the development of innovative biomaterials for tissue treatment and regeneration. The company focuses on creating an antimicrobial tissue-scaffolding matrix that addresses the challenge of antibiotic-resistant bacteria while facilitating tissue regeneration. Utilizing bioinspired and engineering approaches, Gel4Med's technology aims to improve patient outcomes in various therapeutic areas, particularly in wound care and tissue regeneration. Their leading asset features a self-assembling peptide technology that acts as both an antibacterial barrier and a promoter of tissue regeneration, enabling patients to prevent infections during surgical procedures.