National Science Foundation

Eradivir is a biotechnology company based in West Lafayette, Indiana. Founded in 2020, it focuses on developing a non-immunological targeting agent to combat the virus causing COVID-19.

Indiana Wesleyan University is a Christian comprehensive university of The Wesleyan Church. The University was founded in 1920 as Marion College and is committed to liberal arts and professional education. Indiana Wesleyan is the largest member of the Council for Christian Colleges and Universities, the largest private college in Indiana, based on enrollment, and is one of the largest employers in Grant County. Nearly 3,000 students are enrolled in traditional programs on the University’s 350-acre residential campus in Marion. Most buildings on the Marion campus have been built in the past 25 years, so students live and learn in a visually striking environment with well-appointed residence halls and academic facilities, all on a campus that is only an hour away from both Fort Wayne and Indianapolis. IWU offers more than 80 undergraduate degrees, 38 graduate degrees and 5 doctorate degrees and students represent more than 80 Christian denominations and 10 foreign countries.

Amplified Sciences is a molecular diagnostics company developing a point-of-care platform that enables early detection of debilitating diseases. Its sensor-based and optical reporter systems, combined with machine learning and multi-analyte assays, target cancers and chronic conditions such as pancreatic cancer and kidney disease. The technology supports detection of low-abundance disease markers in urine and saliva, with scalability to cost-effective point-of-care formats. The company leverages ultra-sensitive sensing and composition-of-matter intellectual property licensed from Purdue University to deliver single-molecule level detection. Its portfolio aims to improve patient outcomes by enabling rapid, minimally invasive testing, reducing unnecessary procedures, and expediting diagnosis across oncology and other disease areas. The platform has demonstrated prototype data and is positioned for broad applicability across multiple disease states.

GeniPhys develops and commercializes standardized tunable collagen polymers and collagen-fibril materials for research and medical applications. It manufactures research-grade collymers and polymerization reagents that enable customization of 3D collagen-fibril matrices for in-vitro tissue systems used in drug discovery, toxicity testing, and basic cell and tissue research, as well as engineered tissue and organ constructs and 3D bioprinting. The product line includes oligomer polymerization kits, polymerization buffers, supplements, and related reagents, which are sold online. Founded in 2014 and based in Zionsville, Indiana, the company focuses on designing collagen materials for site-appropriate tissue generation and potential delivery of pharmaceutical and cell-based therapies.

Founded in 2018, Valgotech is a technology company based in Fishers, Indiana. It specializes in advanced materials and energy storage systems, aiming to make energy consumption more sustainable and affordable.

Compact Medical Solutions develops a medical bag-valve-mask used to assist patients experiencing emergency breathing issues. The ultra-compact device aims to improve resuscitation by preventing hyperventilation and enabling medical personnel to safely ventilate patients whose breathing is compromised. Founded in 2016 and based in Indianapolis, Indiana, the company focuses on creating portable respiratory support tools for first responders and healthcare providers.

CRCL Solutions, founded in 2021 and based in South Bend, Indiana, specializes in wind and solar forecasting services for energy markets, particularly within ERCOT's day-ahead and real-time markets. The company offers a weather forecasting platform designed to enhance forecast accuracy and strengthen power grid resiliency. By leveraging artificial intelligence, CRCL Solutions identifies discrepancies in current wind and solar forecasts and delivers improved atmospheric forecasting in real-time. This enables power traders to engage in low-risk, high-return trades and better anticipate market movements, ultimately supporting more efficient and reliable energy trading.

Lucata Corporation is a technology company that specializes in enhancing memory utilization through its innovative hardware and software solutions. Founded in 2008 and headquartered in New York City, with additional offices in South Bend, Indiana, Lucata develops motherboards, node cards, and memory servers tailored for various applications such as graph analysis, cyber security, data warehousing, machine learning, and risk analysis. Utilizing patented migrating thread technology, Lucata enables organizations to conduct high-performance analytics on extensive databases exceeding one trillion vertices, facilitating deeper insights into complex data relationships. Its solutions are designed for sectors including financial services, healthcare, telecommunications, and government, allowing for real-time analysis and scalable memory architecture without the need for additional software layers. Lucata's architecture supports energy-efficient processing and significant performance enhancements as hardware scales, positioning the company as a key player in the evolving landscape of big data and analytics.

MITS develops multiscale integrated technology solutions to improve mechanical, thermal, and electrical performance. The company was founded in 2019 and is headquartered in Carmel, Indiana.

South Bend Woodworks, established in 2013 and headquartered in South Bend, Indiana, specializes in creating handcrafted wooden toys and furniture designed for small children. The company offers a diverse product range that includes personalized name puzzles, memorabilia, blocks, cutting boards, and various play accessories. By focusing on high-quality craftsmanship, South Bend Woodworks aims to provide children with engaging and educational play experiences while also offering unique legacy gifts.

Eradivir is a biotechnology company based in West Lafayette, Indiana. Founded in 2020, it focuses on developing a non-immunological targeting agent to combat the virus causing COVID-19.

Ateios Inc. is a technology company based in Indianapolis, Indiana, specializing in the development of ultra-thin and customizable batteries for use in flexible electronics. Founded in 2018, Ateios focuses on zinc-oxide battery technology, which offers significantly higher energy density compared to traditional coin cells. The company's innovative manufacturing process enables the production of batteries that can be tailored to fit the specific requirements of various applications, including smart textiles, soft robotics, Internet-of-Things (IoT) devices, and wearable medical and fitness patches. By advancing the capabilities of thin and flexible electronics, Ateios is positioned to support the growing demand for integrated energy solutions in diverse industries.

Terran Robotics is a construction company based in Bloomington, Indiana, that focuses on the integration of artificial intelligence and robotics in home construction. The company specializes in automated adobe wall building, utilizing a custom-designed cable-driven robot to create three-dimensional printed homes. This innovative approach enhances traditional earthen building techniques, offering features such as fire resistance and superior sound dampening. By leveraging advanced technology, Terran Robotics aims to significantly reduce housing costs, lower energy expenses, and promote environmentally friendly construction practices.

Founded in 2013, MIFtek specializes in developing advanced cellular analysis platforms. These platforms are designed to extract intricate information from cells, utilizing innovative detectors and methods. Headquartered in West Lafayette, Indiana, the company empowers research organizations to understand cellular systems and their functions.

RightFit Analytics is a company founded in 2018 and located in West Lafayette, Indiana, specializing in a precision health-focused analytics platform. The platform employs artificial intelligence to analyze historical data and identify success patterns related to medical operations. By assessing physician strengths in relation to patient characteristics, RightFit Analytics empowers hospitals to make evidence-driven decisions that enhance their operational effectiveness. The company's innovative approach aims to improve healthcare outcomes by leveraging data insights to optimize medical practices.

Founded in 2018, Valgotech is a technology company based in Fishers, Indiana. It specializes in advanced materials and energy storage systems, aiming to make energy consumption more sustainable and affordable.

Founded in 1869, Purdue University is a public land-grant research university located in West Lafayette, Indiana. It is renowned for its programs in science, technology, engineering, and agriculture, offering a wide range of undergraduate and graduate degrees.

MITO Material Solutions is a specialty chemical company that develops and manufactures graphene-based hybrid polymer modifiers and nano-additives to improve the durability and performance of composite materials. Its product lines include hybridized graphene oxide and epoxide-based modifiers that strengthen fiber-reinforced thermoset and thermoplastic resins, and the E-GO material used in carbon fiber components. The company also markets the T-Series nano-additives, which toughen epoxy and resin systems to increase toughness and reduce material usage. These additives are used in resins and thermoplastics such as PA66 and find applications across aerospace, automotive, wind energy, and transportation sectors, including RVs and boats. MITO was founded in 2016 and is based in Indianapolis, with an additional office in Stillwater, Oklahoma.

NutraMaize is an Indiana-based AgBioScience company specializing in the commercialization of a non-GMO corn variety that is both more nutritious and better tasting. Its proprietary corn possesses a deep orange color due to its high carotenoid content, offering consumers potential health benefits such as antioxidant and anti-inflammatory properties.

Founded in 1869, Purdue University is a public land-grant research university located in West Lafayette, Indiana. It is renowned for its programs in science, technology, engineering, and agriculture, offering a wide range of undergraduate and graduate degrees.

GeniPhys develops and commercializes standardized tunable collagen polymers and collagen-fibril materials for research and medical applications. It manufactures research-grade collymers and polymerization reagents that enable customization of 3D collagen-fibril matrices for in-vitro tissue systems used in drug discovery, toxicity testing, and basic cell and tissue research, as well as engineered tissue and organ constructs and 3D bioprinting. The product line includes oligomer polymerization kits, polymerization buffers, supplements, and related reagents, which are sold online. Founded in 2014 and based in Zionsville, Indiana, the company focuses on designing collagen materials for site-appropriate tissue generation and potential delivery of pharmaceutical and cell-based therapies.

Vibronix Inc., established in 2013 by Drs. Ji-Xin Cheng and Pu Wang at Purdue University, specializes in developing advanced healthcare equipment for cancer diagnosis and treatment. Based in West Lafayette, Indiana, with an additional office in Suzhou, China, the company offers innovative imaging tools such as LipoPAT (multi-modal intraoperative imaging tool), AcouStar (optoacoustic fiber guide with augmented reality), and IVPA (intravascular photoacoustic catheter system). These technologies facilitate surgical guidance, enable real-time disease characterization, and aid in assessing therapeutic efficacy.

PC Krause and Associates (PCKA) was incorporated in the state of Indiana in 1983. After the successful completion of several small task-ordered contracts with government agencies and Midwest utilities, PCKA was starting to become recognized as an up-and-coming consulting company with highly-talented engineers. It is a high-tech company with a concentration of high-level expertise in the dynamics of electromechanical systems with particular emphasis on power-electronic-based systems of the types to be found in advanced aircraft, ships, and ground vehicles. The company has a well-established reputation for solving engineering challenges through the use of advanced modeling, simulation, analysis, and control techniques.

MITO Material Solutions is a specialty chemical company that develops and manufactures graphene-based hybrid polymer modifiers and nano-additives to improve the durability and performance of composite materials. Its product lines include hybridized graphene oxide and epoxide-based modifiers that strengthen fiber-reinforced thermoset and thermoplastic resins, and the E-GO material used in carbon fiber components. The company also markets the T-Series nano-additives, which toughen epoxy and resin systems to increase toughness and reduce material usage. These additives are used in resins and thermoplastics such as PA66 and find applications across aerospace, automotive, wind energy, and transportation sectors, including RVs and boats. MITO was founded in 2016 and is based in Indianapolis, with an additional office in Stillwater, Oklahoma.

VinSense is an Indiana-based company established in March 2015, focused on developing an innovative decision support software system tailored for agricultural crop production, particularly in the wine grape growing and winemaking sectors. The platform empowers producers, field managers, and winemakers to enhance crop management decisions, ultimately improving production volume, uniformity, and quality while promoting long-term sustainability and profitability. By utilizing real-time information, predictive modeling, and advanced scientific research in soil, viticulture, and enology, VinSense enables users to make timely interventions in areas such as cover crop management, irrigation practices, and nutrient management. The software features a user-friendly visual interface that transforms complex data into actionable insights, ensuring relevance and accessibility for its users. This comprehensive approach not only aids in optimizing yield quality but also supports better environmental protection and water conservation practices.

NutraMaize is an Indiana-based AgBioScience company specializing in the commercialization of a non-GMO corn variety that is both more nutritious and better tasting. Its proprietary corn possesses a deep orange color due to its high carotenoid content, offering consumers potential health benefits such as antioxidant and anti-inflammatory properties.

Sintact Medical Systems, Inc. is a medical technology company based in Bloomington, Indiana, founded in 2013. The company specializes in the development of non-resorbable films designed to prevent surgical adhesions, which are internal scar formations that cause adjacent organs and tissues to stick together following surgery. These films serve as a barrier, effectively separating organ and tissue surfaces to minimize the risk of adhesion formation and related post-operative complications. By providing a clear plane of dissection, Sintact's products also enhance the ease of re-operation when necessary, ultimately improving patient outcomes and advancing surgical practices.

Founded in 2014, Mobile Enerlytics develops technologies that enhance smartphone battery life. Its flagship product, Estar, helps users install energy-efficient apps and remove power-draining ones. Eprof, its diagnostic tool, aids app creators in minimizing battery drain.

Vibronix Inc., established in 2013 by Drs. Ji-Xin Cheng and Pu Wang at Purdue University, specializes in developing advanced healthcare equipment for cancer diagnosis and treatment. Based in West Lafayette, Indiana, with an additional office in Suzhou, China, the company offers innovative imaging tools such as LipoPAT (multi-modal intraoperative imaging tool), AcouStar (optoacoustic fiber guide with augmented reality), and IVPA (intravascular photoacoustic catheter system). These technologies facilitate surgical guidance, enable real-time disease characterization, and aid in assessing therapeutic efficacy.

Spero Energy, Inc. is an Indiana based company with the mission of developing cost competitive processes for the conversion of abundant non-food biomass to high value chemicals (HVCs) and renewable fuels. With its experienced and outstanding research and business team, Spero Energy has developed processes for a range of renewable chemicals targeting the flavor, fragrance, and pharmaceutical industries. Our initial lignin-derived flavor and fragrance chemicals target a multi-billion dollar market segment.

PC Krause and Associates (PCKA) was incorporated in the state of Indiana in 1983. After the successful completion of several small task-ordered contracts with government agencies and Midwest utilities, PCKA was starting to become recognized as an up-and-coming consulting company with highly-talented engineers. It is a high-tech company with a concentration of high-level expertise in the dynamics of electromechanical systems with particular emphasis on power-electronic-based systems of the types to be found in advanced aircraft, ships, and ground vehicles. The company has a well-established reputation for solving engineering challenges through the use of advanced modeling, simulation, analysis, and control techniques.

Founded in 1869, Purdue University is a public land-grant research university located in West Lafayette, Indiana. It is renowned for its programs in science, technology, engineering, and agriculture, offering a wide range of undergraduate and graduate degrees.

VinSense is an Indiana-based company established in March 2015, focused on developing an innovative decision support software system tailored for agricultural crop production, particularly in the wine grape growing and winemaking sectors. The platform empowers producers, field managers, and winemakers to enhance crop management decisions, ultimately improving production volume, uniformity, and quality while promoting long-term sustainability and profitability. By utilizing real-time information, predictive modeling, and advanced scientific research in soil, viticulture, and enology, VinSense enables users to make timely interventions in areas such as cover crop management, irrigation practices, and nutrient management. The software features a user-friendly visual interface that transforms complex data into actionable insights, ensuring relevance and accessibility for its users. This comprehensive approach not only aids in optimizing yield quality but also supports better environmental protection and water conservation practices.

Phytoption is a company focused on developing natural-derived materials and biopolymers from agricultural commodities for use across the food, health, pharmaceutical, personal care, and agricultural sectors. It specializes in phytoglycogen-based biopolymers and other enabling ingredients that enhance product performance, including antimicrobial agents, cosmetic formulations, and pharmaceutical substances. These components are designed to improve solubility, shelf life, sensory properties, bioavailability, functionality, and nutritional value of end products. Serving customers in pharma, personal care, agriculture, and the food-and-beverage industries, Phytoption operates from West Lafayette, Indiana, and was founded in 2011. The company emphasizes sustainable, natural-derived materials sourced from agricultural feedstocks to support applications in health, nutrition, and consumer products.

Founded in 2014, Mobile Enerlytics develops technologies that enhance smartphone battery life. Its flagship product, Estar, helps users install energy-efficient apps and remove power-draining ones. Eprof, its diagnostic tool, aids app creators in minimizing battery drain.

SensorHound Innovations LLC, founded in 2012 and based in West Lafayette, Indiana, specializes in Internet of Things (IoT) software products and services aimed at minimizing development and operational costs. The company has developed a proactive and automated operations monitoring platform that addresses the critical issues of reliability and security in IoT applications. By providing continuous monitoring, the platform detects failures, security vulnerabilities, and performance issues in real time, delivering immediate alerts and detailed diagnostic information to facilitate rapid root cause analysis. This innovative solution, built on over a decade of research by leading IoT experts, significantly enhances the efficiency of monitoring operations, ultimately reducing maintenance costs associated with IoT deployments.

Founded in 2011, Animated Dynamics specializes in developing and commercializing live-tissue imaging platform technologies. Its core product, BioDynamic Imaging, uses low-coherence digital holography to probe up to 1 mm deep into living tissue, providing label-free, physiologically meaningful drug assessment in three-dimensional samples.

Sintact Medical Systems, Inc. is a medical technology company based in Bloomington, Indiana, founded in 2013. The company specializes in the development of non-resorbable films designed to prevent surgical adhesions, which are internal scar formations that cause adjacent organs and tissues to stick together following surgery. These films serve as a barrier, effectively separating organ and tissue surfaces to minimize the risk of adhesion formation and related post-operative complications. By providing a clear plane of dissection, Sintact's products also enhance the ease of re-operation when necessary, ultimately improving patient outcomes and advancing surgical practices.

Founded in 2011, Animated Dynamics specializes in developing and commercializing live-tissue imaging platform technologies. Its core product, BioDynamic Imaging, uses low-coherence digital holography to probe up to 1 mm deep into living tissue, providing label-free, physiologically meaningful drug assessment in three-dimensional samples.

Spero Energy, Inc. is an Indiana based company with the mission of developing cost competitive processes for the conversion of abundant non-food biomass to high value chemicals (HVCs) and renewable fuels. With its experienced and outstanding research and business team, Spero Energy has developed processes for a range of renewable chemicals targeting the flavor, fragrance, and pharmaceutical industries. Our initial lignin-derived flavor and fragrance chemicals target a multi-billion dollar market segment.

WisdomTools LLC is a company that specializes in developing immersive and context-aware eLearning technologies tailored for various industries, including professional services, education, finance, and government. Founded in 1998 and headquartered in Bloomington, Indiana, the company creates customized training solutions incorporating virtual world simulations, serious games, and augmented reality. These offerings are designed to enhance learning experiences and performance across diverse settings, such as individual learning and hybrid eLearning environments. WisdomTools also provides a range of services, from game concept development and instructional design to usability testing and cognitive task analysis. By focusing on story-based and problem-based training approaches, WisdomTools aims to foster effective learning and retention, catering to the needs of both learners and organizations. The company operates as a subsidiary of Information in Place, Inc.

Nano-Meta Technologies develops and commercializes intellectual property. The company offers nano-antennas for heat-assisted magnetic data recording, ultra-thin optical elements, meta-surfaces, and chemical/bio/medical sensing and probing applications. It was founded in 2010 and headquartered in West Lafayette, Indiana.

Purdue Research Park, established in association with Purdue University, serves as a hub for innovation and entrepreneurship. It offers networking opportunities through events like Party in the Park, seminars, and academies, fostering collaboration among its tenants. The park provides low-cost or complimentary services to its occupants, enhancing their business operations.

SensorHound Innovations LLC, founded in 2012 and based in West Lafayette, Indiana, specializes in Internet of Things (IoT) software products and services aimed at minimizing development and operational costs. The company has developed a proactive and automated operations monitoring platform that addresses the critical issues of reliability and security in IoT applications. By providing continuous monitoring, the platform detects failures, security vulnerabilities, and performance issues in real time, delivering immediate alerts and detailed diagnostic information to facilitate rapid root cause analysis. This innovative solution, built on over a decade of research by leading IoT experts, significantly enhances the efficiency of monitoring operations, ultimately reducing maintenance costs associated with IoT deployments.

Phytoption is a company focused on developing natural-derived materials and biopolymers from agricultural commodities for use across the food, health, pharmaceutical, personal care, and agricultural sectors. It specializes in phytoglycogen-based biopolymers and other enabling ingredients that enhance product performance, including antimicrobial agents, cosmetic formulations, and pharmaceutical substances. These components are designed to improve solubility, shelf life, sensory properties, bioavailability, functionality, and nutritional value of end products. Serving customers in pharma, personal care, agriculture, and the food-and-beverage industries, Phytoption operates from West Lafayette, Indiana, and was founded in 2011. The company emphasizes sustainable, natural-derived materials sourced from agricultural feedstocks to support applications in health, nutrition, and consumer products.

Spensa Technologies Inc. is a company that specializes in developing software and technology solutions for the agriculture sector. Founded in 2009 and based in West Lafayette, Indiana, Spensa offers a range of tools designed to enhance crop protection and efficiency. Its flagship products include OpenScout, a mobile application for recording and tagging field notes and photos, and MyTraps, a tool for collecting and visualizing pest data. Additionally, the company provides Z-Trap, a smart insect trap system that helps farmers analyze and predict pest populations. With a mission to reduce reliance on manual labor while promoting sustainable farming practices, Spensa leverages advanced expertise in wireless sensor networks, robotics, and computer vision to innovate within the agricultural industry. As a subsidiary of Telvent DTN, LLC since 2018, Spensa continues to focus on fostering eco-friendly farming and improving agricultural productivity.

Founded in 2010, Tymora specializes in providing analytical tools for life sciences research. It offers products like pIMAGO and PolyMAC for detecting and isolating phosphoproteins, serving clients globally through distributors and online.

Medtric Biotech, LLC, founded in 2010 and based in Lafayette, Indiana, specializes in the development and commercialization of antibiotic-free germicidal solutions for various sectors, including medical, consumer, industrial, and agricultural applications. The company employs water-based nano-emulsion technology that utilizes plant-derived compounds as antimicrobial agents, enabling the creation of a range of products such as wound care solutions, hand sanitizers, skin antiseptics, and sanitizers designed to enhance shelf-life and consumer health. Medtric Biotech aims to address the growing challenge of antimicrobial resistance by offering innovative and clinically robust products, focusing on advancing patient care and expanding into various markets, including clinical and over-the-counter wound care, as well as treatment for topical infections like acne.

SmarterShade is a company based in South Bend, Indiana, specializing in innovative light-control technology that allows users to electronically darken windows, skylights, and other glass surfaces with ease. This technology enhances privacy and energy efficiency by enabling adjustable light levels based on individual preferences. SmarterShade's proprietary aftermarket solution can be applied to various glass surfaces, including residential doors and rear-view mirrors, making it versatile for both home and commercial applications. By integrating this smart tinting feature into buildings, SmarterShade aims to contribute to energy savings and improved comfort, positioning itself as a key player in the clean technology sector.