National Institutes of Health

The National Institutes of Health (NIH) is a leading biomedical research facility in the United States, operating under the Department of Health and Human Services. Established in 1887 and based in Bethesda, Maryland, NIH is the primary agency responsible for biomedical and health-related research in the country. It comprises 27 separate institutes and centers, each focusing on different disciplines within biomedical science. NIH conducts its own scientific research through the Intramural Research Program and provides significant funding for research at external institutions via the Extramural Research Program. With a workforce that includes 1,200 principal investigators and over 4,000 postdoctoral fellows, NIH has been instrumental in major medical breakthroughs, such as the development of vaccines for hepatitis and human papillomavirus, as well as the discovery of treatments for various health conditions. As the world's largest source of medical research funding, NIH continues to advance scientific knowledge and contribute to public health improvements.

Francis Collins

Director

Nick Langhals

Supervisory Program Director

Past deals in Personal Health

UCLA Health System

Grant in 2025
Comprised of Ronald Reagan UCLA Medical Center, UCLA Medical Center, Santa Monica; Resnick Neuropsychiatric Hospital at UCLA, Mattel Children's Hospital UCLA, and the UCLA Medical Group with its wide-reaching system of primary-care and specialty-care offices throughout the region, UCLA Health System is among the most comprehensive and advanced healthcare systems in the world.

Caretaker Medical

Grant in 2024
CareTaker is the worlds most innovative patient monitor Using only a simple finger cuff to measure Continuous Beat-by-Beat Blood Pressure (“cNIBP”), Heart Rate, and other physiological parameters enabling safe, secure, and accurate remote patient monitoring via their secure Android App, HIPPA-compliant Cloud Portals, or interfaced with other patient monitoring systems. CareTaker sets a new standard in mobility, simplicity, and cost, enabling continuous realtime monitoring as patients traverse the full continuum of care, within the hospital, during transport, and after discharge.

Metabolon

Grant in 2024
Metabolon, Inc. is a health technology company specializing in metabolomics, which focuses on the analysis of metabolites to aid in disease detection and precision medicine. The company develops a range of clinical diagnostic tests, including QUANTOSE IR for early-stage insulin resistance and Meta IMD for identifying metabolites linked to inherited metabolic disorders. Metabolon also offers customizable research services and multiomics solutions, enabling academic and commercial researchers to explore various life sciences areas effectively. The company's technologies address a wide array of health conditions, including cardiovascular issues, diabetes, and cancer, and are utilized across sectors such as biotechnology, pharmaceuticals, and nutrition. Founded in 2000 and headquartered in Morrisville, North Carolina, Metabolon has a global presence, including offices in Munich, London, Madrid, and China, and maintains strategic partnerships with major firms in the pharmaceutical and consumer health industries.

Preeclampsia Foundation

Grant in 2024
Preeclampsia Foundation is a nonprofit that focuses on reducing maternal and infant illness and death due to preeclampsia.

AegirBio

Grant in 2023
AegirBio AB is a Swedish diagnostics company focused on developing innovative home testing solutions for oral health, therapeutic drug monitoring, and infectious diseases. The company has established a platform that enhances lateral flow tests, significantly improving their sensitivity and precision compared to traditional methods. AegirBio's product lineup includes the Veritope technology, which measures intact natalizumab for multiple sclerosis, alongside the MagniaReader, designed for both research and veterinary use. Their advancements enable robust, affordable, and easy-to-use testing instruments applicable across human health, veterinary, food safety, and environmental sectors. By leveraging novel techniques, AegirBio aims to expand the market for lateral flow tests and enhance patient care through more reliable diagnostics.

Satio

Grant in 2023
Satio brings a dried blood spot and whole blood collection to the consumer; simple, painless, and clean using patches.

PediaMetrix

Grant in 2023
PediaMetrix Inc. is a company focused on developing innovative digital solutions for pediatric head measurement and monitoring. Founded in 2018 by alumni from Johns Hopkins, NIH, and Oxford, the company is based in Rockville, Maryland. Its primary product, SoftSpot, is a mobile application that leverages artificial intelligence and computer vision to provide accurate measurements of infants' head shapes. This app allows parents to receive personalized repositioning instructions and enables pediatricians to access easy-to-understand data analysis, facilitating timely and effective care. By focusing on early detection and management of head shape abnormalities, PediaMetrix aims to enhance healthcare outcomes and reduce costs associated with pediatric care.

CardieX

Grant in 2023
CardieX is a global health technology company that focuses on hypertension, cardiovascular disease, and other vascular health disorders.

Behaivior

Grant in 2023
Behaivior LLC is a digital health company based in Pittsburgh, Pennsylvania, focused on predicting and preventing addiction relapses through innovative technology. Founded in 2017, Behaivior develops a platform that combines wearable devices and machine learning algorithms to monitor key physiological signals such as heart rate and motion. This system, known as Recovery, is designed to support mental health recovery and wellness by delivering timely interventions based on real-time data. By utilizing a software-as-a-service (SaaS) model, Behaivior empowers individuals to maintain their recovery process while enabling care providers to better assist their clients. The integration of AI and behavioral health technology allows Behaivior to recognize patterns in human behavior, ultimately aiming to enhance mental well-being and reduce the incidence of crises, including relapse.

Ria Health

Grant in 2022
Ria Health is an online platform that provides telehealth services for individuals looking to improve their relationship with alcohol. It offers personalized treatment plans that include medication-assisted treatment options and behavioral therapies, all supported by licensed healthcare professionals. The platform emphasizes continuous monitoring to help users track their progress and maintain accountability in their recovery journey. Ria Health features a mobile app that grants users access to educational materials, support groups, and direct communication with care teams. This comprehensive approach aims to assist individuals in managing alcohol consumption and fostering healthier habits.

Whitman-Walker Health

Grant in 2022
Whitman-Walker Health provides health and wellness services. They provide HIV, prep, pep, medical and community care, insurance navigation services, gender affirming care and services, youth and family support, legal services, dental health, and behavorial health services.

Coprata

Grant in 2022
Coprata is a digital health and technology company that offers innovative solutions for monitoring gut health through stool analysis and artificial intelligence. By enabling hands-free stool sampling and automated monitoring of bowel movements during regular toilet use, Coprata provides individuals with valuable insights into their gut health. This service allows users to track the effects of their lifestyle choices and receive early warnings about potential changes in their gut health. The platform aims to facilitate the detection and management of both acute and chronic gastrointestinal diseases, as well as infectious diseases. Additionally, Coprata is focused on developing non-invasive methods for health monitoring that seamlessly integrate into daily routines, ultimately enhancing personalized wellness and health management.

PediaMetrix

Grant in 2022
PediaMetrix Inc. is a company focused on developing innovative digital solutions for pediatric head measurement and monitoring. Founded in 2018 by alumni from Johns Hopkins, NIH, and Oxford, the company is based in Rockville, Maryland. Its primary product, SoftSpot, is a mobile application that leverages artificial intelligence and computer vision to provide accurate measurements of infants' head shapes. This app allows parents to receive personalized repositioning instructions and enables pediatricians to access easy-to-understand data analysis, facilitating timely and effective care. By focusing on early detection and management of head shape abnormalities, PediaMetrix aims to enhance healthcare outcomes and reduce costs associated with pediatric care.

Enspectra Health

Grant in 2022
Enspectra Health, based in Mountain View, California, specializes in developing advanced imaging systems for medical applications. The company has created the first hand-held multiphoton imager for human use, enabling real-time imaging of live cellular anatomy beneath the skin. Its innovative device combines reflectance confocal and multiphoton laser scanning microscopy to produce multispectral images that reveal details not visible to the naked eye. This technology aids researchers and dermatologists in examining the structure and function of various tissues, including muscle, tendon, cartilage, and skin, thereby enhancing the diagnosis and treatment of skin conditions, particularly skin cancers. Enspectra Health aims to simplify the evaluation process for physicians and improve patient outcomes through its cutting-edge imaging solutions.

Epicore Biosystems

Series A in 2022
Epicore Biosystems, Inc. is a Cambridge, Massachusetts-based company founded in 2017 that specializes in developing and commercializing a wearable microfluidic sensing platform. This innovative technology analyzes small droplets of sweat directly from the skin to provide insights into health, hydration, and athletic performance. The platform is designed to measure various biomarkers, including proteomics and inflammatory markers, allowing for personalized management of health and nutrition. Epicore's approach leverages over two decades of research in microfluidics and soft materials conducted by leading experts at Northwestern University. By offering a non-invasive and cost-effective solution, Epicore aims to enhance athletic performance and improve overall health monitoring for users.

Bleep

Grant in 2021
Bleep provides best new CPAP solution on the market. Not sleeping sucks. Not sleeping and spending a fortune on CPAP devices that leak, fall off or leave marks on your face sucks even worse. That’s why they invented the DreamPort Sleep Solution – the world’s first-ever mask less CPAP device. The result is the smallest, lightest, most ergonomically accommodating CPAP solution on the market – a device that fits comfortably and doesn’t restrict your movement – enabling patients to get a better night’s sleep. Their goal is simple – to make the best bleeping CPAP products on the planet. They won’t stop until every sleep apnea patient is sleeping like a baby.

Viora Health

Pre Seed Round in 2021
Viora Health is a health and wellness company focused on advancing health equity among diverse populations. It offers tech-enabled, human-centered programs that utilize social and behavioral engagement to enhance capacity, satisfaction, outcomes, and revenue for healthcare providers. The company is backed by funding from reputable organizations such as the American Heart Association, the National Institutes of Health, Johnson and Johnson, and the National Science Foundation, with its initiatives validated through an Institutional Review Board-approved study. Viora Health's programs have demonstrated a 75% satisfaction score, double retention rates, and improved health outcomes, including reduced stress and better access to food and social support. Additionally, Viora Health develops a healthcare compliance platform aimed at enhancing adherence to diabetes prevention initiatives by connecting patients to programs, tracking data, and facilitating online engagement tools, which help diabetes prevention programs comply with insurance requirements and achieve outcome-based reimbursement.

Soterya

Seed Round in 2021
On average, we spend a third of our lives in bed. Our self-positioning bed; the Korus™, combined with our AI-driven software, is designed to provide precise sleep therapies improving lifestyle and medical care that benefits sleep wellness and faster recovery at home.

Enspectra Health

Grant in 2021
Enspectra Health, based in Mountain View, California, specializes in developing advanced imaging systems for medical applications. The company has created the first hand-held multiphoton imager for human use, enabling real-time imaging of live cellular anatomy beneath the skin. Its innovative device combines reflectance confocal and multiphoton laser scanning microscopy to produce multispectral images that reveal details not visible to the naked eye. This technology aids researchers and dermatologists in examining the structure and function of various tissues, including muscle, tendon, cartilage, and skin, thereby enhancing the diagnosis and treatment of skin conditions, particularly skin cancers. Enspectra Health aims to simplify the evaluation process for physicians and improve patient outcomes through its cutting-edge imaging solutions.

Xtrava

Grant in 2021
Xtrava Health specializes in creating and commercializing user-friendly diagnostic products for both health professionals and consumers. The company focuses on developing medical devices that enhance respiratory health monitoring, employee wellness, and baby monitoring, thereby addressing practical health-related challenges. By leveraging advanced technology and forming strategic global partnerships, Xtrava aims to provide accurate and affordable diagnostic solutions that simplify the process of health monitoring for everyday users.

Arcascope

Grant in 2020
Arcascope makes apps that utilize algorithms that track circadian rhythms and generates personalized recommendations to help people get their clocks back on track.

Intake Health

Grant in 2019
Intake Health is a developer of a continuous passive health monitoring device that operates at home without requiring changes in user behavior. The device is designed to be mounted on a toilet, where it automatically tests urine from flush water to deliver lab-quality results for various health and dietary indicators. By leveraging advanced biosensors and wireless technology, the system accurately tracks hydration and nutrition by quantifying specific urinary biomarkers. Users receive instant insights on their health metrics through a mobile application, facilitating informed decision-making regarding their well-being. Intake Health aims to enhance health predictions and personalized prevention strategies through the accumulation of personalized biomarkers over time. The company has received funding from the National Science Foundation and the National Institutes of Health.

Hackensack Meridian Health

Grant in 2019
Hackensack Meridian Health is a not-for-profit healthcare organization based in New Jersey that provides a comprehensive range of medical services and life-enhancing care. The organization operates a network that includes ambulatory care centers, surgery centers, home health services, long-term care facilities, and assisted living communities. Additionally, it offers ambulance services, lifesaving air medical transportation, rehabilitation services, urgent care, and fitness and wellness centers. Through its integrated approach, Hackensack Meridian Health aims to deliver innovative research and improve health outcomes for the communities it serves.

Recovery Force

Grant in 2019
Recovery Force Health, LLC, based in Fishers, Indiana, specializes in the development and manufacturing of innovative health care apparel and wearable medical technology. Founded in 2013 by Matthew Wyatt, the company emerged from a personal experience where Wyatt sought to improve patient care following surgical procedures. Recovery Force offers a range of products, including sleeves and shoes, designed for healthcare professionals, patients, and athletes. Central to their offerings is the MORPH system, which utilizes S.M.A.R.T. technology and nitinol to provide rhythmic, sequential compression that enhances blood flow to targeted areas of the body. Their non-pneumatic platform aims to reduce post-operative pain and swelling, expedite wound healing, treat chronic lymphedema, and alleviate joint pain and muscle soreness. Recovery Force is committed to integrating data-driven solutions throughout the continuum of care, from hospital settings to home recovery.

Bruin Biometrics

Grant in 2018
Bruin Biometrics LLC specializes in the development and manufacture of biometric-sensor based medical devices aimed at the early identification and monitoring of chronic and preventable conditions. The company offers innovative point-of-care solutions such as the Provizio SEM Scanner, a handheld wireless device designed for assessing the risk of pressure injuries and ulcers, as well as the OrthoSonos, which monitors joint health through acoustic emissions. Founded in 2009 and headquartered in Los Angeles, California, with an additional office in Manchester, United Kingdom, Bruin Biometrics is focused on delivering effective solutions for wound care and orthopedic care, emphasizing real-time data capture, analytics, and reporting. The company has licensed wireless health technologies from the UCLA Wireless Health Institute, aiming to address significant medical needs through its portfolio of patent-protected, FDA-approved devices.

Arcascope

Grant in 2018
Arcascope makes apps that utilize algorithms that track circadian rhythms and generates personalized recommendations to help people get their clocks back on track.

Behaivior

Grant in 2018
Behaivior LLC is a digital health company based in Pittsburgh, Pennsylvania, focused on predicting and preventing addiction relapses through innovative technology. Founded in 2017, Behaivior develops a platform that combines wearable devices and machine learning algorithms to monitor key physiological signals such as heart rate and motion. This system, known as Recovery, is designed to support mental health recovery and wellness by delivering timely interventions based on real-time data. By utilizing a software-as-a-service (SaaS) model, Behaivior empowers individuals to maintain their recovery process while enabling care providers to better assist their clients. The integration of AI and behavioral health technology allows Behaivior to recognize patterns in human behavior, ultimately aiming to enhance mental well-being and reduce the incidence of crises, including relapse.

HealthRhythms

Grant in 2017
HealthRhythms develops a mental health assessment and treatment platform that focuses on measuring and monitoring health conditions. Utilizing advanced machine learning and predictive analytics, the company offers innovative health assessments and personalized interventions aimed at enhancing the care delivery experience for patients, health plans, payers, and research organizations. Its platform enables continuous, objective monitoring of behavioral health, allowing for real-time tracking of mental health status. By anticipating clinical deterioration, HealthRhythms delivers tailored interventions based on individual patient profiles, assisting healthcare providers in effectively identifying, managing, and characterizing patients' mental health needs.

BioSensics

Grant in 2017
Wearable sensors are transforming healthcare by empowering health researchers, care providers, and patients with new insights.Together with their clinical research and enterprise partners, They develop innovative, market driven, wearable sensor solutions that address some of healthcare’s biggest challenges.

Accure Health

Grant in 2017
Accure Health is a privately held precision medicine company dedicated to developing AI-powered solutions that utilize patients' biomarker profiles. The company aims to enhance the delivery of precision therapies by ensuring that treatments are directed to the appropriate cells for the right patients. Accure Health's patented technologies integrate advanced protein design, an automated biomarker device, and a scalable, food-based production system. This innovative approach focuses on improving the targeted delivery of RNA and protein therapeutics, thereby facilitating access to more effective treatments tailored to individual patient needs.

Health Behavior Solutions

Grant in 2017
Health Behavior Solutions exists to break down the barriers to getting evidence-based mental health treatments. Our goal is to empower individuals to manage living with depression through the use of digital health technology augmented with health and wellness coaching. We are building products that actively engage people, while helping them make positive life changes that are readily integrated into their daily routines.

Ossium Health

Grant in 2016
Ossium Health, Inc. is engaged in the development and manufacturing of cell therapy products aimed at treating leukemia, other blood cancers, and tissue damage, as well as addressing radiation poisoning. The company offers a range of innovative therapies, including HPC, Marrow, which features HLA-matched bone marrow stem cells for hematopoietic reconstitution in blood cancer patients; Chimera, which enhances organ transplantation; and Chymalis, composed of mesenchymal stem cells that promote the healing of damaged bone and muscle tissue. Additionally, Ossium provides bone marrow cells for research purposes in oncology and immunology. Founded in 2016 and headquartered in San Francisco, California, Ossium Health focuses on improving health outcomes and longevity through advanced bioengineering techniques.

Neurotrack

Grant in 2016
Neurotrack is a digital health company focused on transforming the diagnosis and management of Alzheimer's and other dementias. Founded in 2012 by Elli Kaplan and neuroscientist Dr. Stuart Zola, the company is headquartered in Redwood City, California. Neurotrack develops user-friendly, clinically validated cognitive assessments that can be administered in clinical settings or at home, allowing for early detection of cognitive impairment and ongoing monitoring of cognitive function. The company's solutions are designed to fit seamlessly into various workflows, enabling healthcare providers to efficiently screen patients for cognitive decline and take necessary next steps. Neurotrack has published 27 peer-reviewed papers, holds 11 patents for its proprietary technology, and is registered as an FDA Class II medical device.

Inova Translational Medicine Institute

Grant in 2016
Inova Translational Medicine Institute (ITMI) is a not-for-profit research institute that applies genomic and clinical information from individuals to develop innovative methods for personalized healthcare. ITMI is part of Inova Center for Personalized Health (ICPH), which connects researchers, clinicians, and consumers to integrate genomic research for patient care, prevention, and wellness. This approach enables individuals to live longer and transforms healthcare from reactive to predictive. Research studies at ITMI generate a large genomic and clinical data set that can be used by researchers in a variety of fields, from computational biology to psychology, and biomedical research applications. ITMI’s utilizes genomic information from an individual to understand the onset of disease, leading to the implementation of preventative medicine, and to increase successful outcomes while reducing adverse reactions to treatment.

Health Behavior Solutions

Grant in 2016
Health Behavior Solutions exists to break down the barriers to getting evidence-based mental health treatments. Our goal is to empower individuals to manage living with depression through the use of digital health technology augmented with health and wellness coaching. We are building products that actively engage people, while helping them make positive life changes that are readily integrated into their daily routines.

Daktari Diagnostics

Grant in 2015
Daktari Diagnostics, Inc. is a healthcare solutions company based in Cambridge, Massachusetts, founded in 2008. The company specializes in developing portable point-of-care diagnostic platforms aimed at improving disease management worldwide, particularly in resource-poor settings. Its key offerings include the Daktari Virology platform for detecting Hepatitis C and HIV, the Daktari InSight data management service that facilitates connectivity between diagnostic systems and healthcare providers, and the Daktari Sickle Cell solution, which enables the identification of infants with sickle cell disease from a single drop of blood. Daktari's products are designed to provide real-time diagnostic information while ensuring that critical data flows efficiently throughout the healthcare system, ultimately supporting better clinical outcomes and global disease elimination efforts.

Daktari Diagnostics

Grant in 2014
Daktari Diagnostics, Inc. is a healthcare solutions company based in Cambridge, Massachusetts, founded in 2008. The company specializes in developing portable point-of-care diagnostic platforms aimed at improving disease management worldwide, particularly in resource-poor settings. Its key offerings include the Daktari Virology platform for detecting Hepatitis C and HIV, the Daktari InSight data management service that facilitates connectivity between diagnostic systems and healthcare providers, and the Daktari Sickle Cell solution, which enables the identification of infants with sickle cell disease from a single drop of blood. Daktari's products are designed to provide real-time diagnostic information while ensuring that critical data flows efficiently throughout the healthcare system, ultimately supporting better clinical outcomes and global disease elimination efforts.

Noom

Grant in 2013
Noom, Inc. is a digital health company that specializes in mobile health coaching solutions aimed at helping individuals manage and prevent chronic conditions such as obesity, diabetes, and hypertension. Founded in 2008 and headquartered in New York City, Noom offers a psychology-based platform that integrates evidence-based curricula with trained cognitive behavior coaches, mobile tracking, and scalable coaching tools. The platform empowers users to achieve their personal health and wellness goals, including weight management and stress reduction. Noom has received multiple grants from the National Institutes of Health and is recognized as a certified diabetes prevention program by the Centers for Disease Control. In addition to serving individual users, Noom also partners with businesses to promote health and wellness initiatives. The company has additional offices in Seoul, South Korea, and Tokyo, Japan.

Insightfil

Grant in 2013
Insightfil is dedicated to positively impacting patient outcomes by reducing medication errors, improving medication adherence (from norm of 40% to NIH goal of 75%), optimizing health professional time, and eliminating wasted drugs and packaging. They are delivering to the market with a unique “Personalized Wellness Portfolio” (PWP) that dispenses custom medication regimens. It is the first of its kind to connect the patient, clinic, and pill manufacturer in the administration of therapy.
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