National Institutes of Health

National Institutes of Health is a biomedical research agency of the U.S. Department of Health and Human Services, based in Bethesda, Maryland. It is the primary U.S. government organization devoted to biomedical and health research, conducting science through the Intramural Research Program and funding external research through the Extramural Research Program. The NIH comprises 27 institutes and centers and supports about 1,200 principal investigators and more than 4,000 postdoctoral fellows across basic, translational, and clinical research. It has contributed to major advances such as vaccines and therapies and is dedicated to advancing knowledge and translating discoveries into improvements in public health. Established in 1887, NIH operates as a central hub for medical research in the United States.

Francis Collins

Director

Nick Langhals

Supervisory Program Director

Past deals in Clinical Trials

SonoMotion

Grant in 2025
SonoMotion Inc. develops non-invasive medical devices for kidney stone disease, including Break Wave for fragmenting large stones and Stone Clear to remove fragments within about 15 minutes in office settings without general anesthesia or X-ray radiation. The company, founded in 2012 and based in San Mateo, California, focuses on office-based procedures that aim to simplify treatment, reduce hospital visits, and offer cost-efficient care for kidney stone patients.

Vast Therapeutics

Grant in 2025
Vast Therapeutics, Inc. is a preclinical-stage pharmaceutical company based in Durham, North Carolina, focused on developing inhalable treatments for antibiotic-resistant pathogens affecting patients with cystic fibrosis and other respiratory diseases. Established in 2017 and previously known as Novoclem Therapeutics, the company aims to address chronic infections that are prevalent in the cystic fibrosis population. Vast Therapeutics operates as a subsidiary of KNOW Bio, LLC, and is dedicated to advancing its innovative therapeutic solutions to improve health outcomes for patients facing these challenging conditions.

Arkansas Children's Research Institute

Grant in 2025
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

Feinstein Institute for Medical Research

Grant in 2025
Feinstein Institute For Medical Research is the research arm of Northwell Health, the largest health care provider and private employer in New York State. Home to 50 research labs, 3,000 clinical research studies and 5,000 researchers and staff, the Feinstein Institutes raises the standard of medical innovation through its five institutes of behavioral science, bioelectronic medicine, cancer, health innovations and outcomes, and molecular medicine. We make breakthroughs in genetics, oncology, brain research, mental health, autoimmunity, and are the global scientific leader in bioelectronic medicine – a new field of science that has the potential to revolutionize medicine.

University of Arkansas for Medical Sciences

Grant in 2025
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Sparian Biosciences

Grant in 2024
Sparian Biosciences is an early-stage biopharmaceutical company dedicated to the discovery and development of innovative therapies for the central nervous system (CNS). The firm specializes in creating unique and transformative medicines that specifically target brain-related conditions. Sparian is committed to advancing therapeutic solutions that address both acute and chronic pain through cutting-edge science and novel drug discovery methods.

Mount Sinai Health System

Grant in 2024
Mount Sinai Health System is an integrated healthcare system based in New York, providing exceptional medical care to local and global communities. Established in 2013 through the merger of Mount Sinai Medical Center and Continuum Health Partners, it encompasses the Icahn School of Medicine and operates seven hospital campuses throughout the New York metropolitan area. The system is recognized for its excellence in research, patient care, and education across various specialties. It features a vast network of over 7,000 primary and specialty care physicians, as well as more than 45 ambulatory practices and 12 minority-owned free-standing ambulatory surgery centers. Mount Sinai is committed to improving healthcare quality and accessibility, focusing on compassionate patient experiences and the development of strong relationships between staff and patients. Additionally, its venture capital arm, Mount Sinai Ventures, invests in healthcare startups, further enhancing its capacity to innovate and respond to the diverse health needs of the populations it serves.

Brixton Biosciences

Grant in 2024
Brixton Biosciences is a clinical-stage life sciences company developing therapies for pain management. The company focuses on non-addictive, locally targeted treatments delivered via a drug-free injectable that produces reversible nerve inhibition, aiming to provide long-lasting relief. Its lead approach seeks to extend pain relief from a single injection to thirty to sixty days, reducing reliance on systemic medications and addressing unmet needs in both chronic and acute pain.

Arkansas Children's Research Institute

Grant in 2024
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

Allyx Therapeutics

Grant in 2024
Allyx Therapeutics, Inc. is a clinical-stage biotechnology company founded in 2018 and based in Durham, Connecticut. The company specializes in developing disease-modifying treatments for Alzheimer's Disease, with a focus on reversing neurodegeneration. Its lead product is an orally bioavailable small molecule that functions as a silent allosteric modulator of mGluR5. This innovative approach aims to provide clinicians with a therapeutic option capable of preserving cognition in patients while addressing the underlying disease mechanisms.

Oklahoma Medical Research Foundation

Grant in 2024
The Oklahoma Medical Research Foundation (OMRF) is a non-profit biomedical research institute dedicated to understanding and treating various devastating illnesses, including Alzheimer's, heart disease, lupus, multiple sclerosis, and cancer. It operates a research facility, providing services and access to resources that facilitate drug discoveries and improve patient care.

Resvita Bio

Grant in 2024
Resvita Bio develops and manufactures engineered probiotics for treating skin-related diseases, including cancer. Leveraging a synthetic biology platform, the company uses genetically engineered bacteria to produce and deliver therapeutic proteins directly to affected skin areas, providing continuous treatment and addressing limitations of traditional therapies. It targets conditions such as Netherton Syndrome and Severe Atopic Dermatitis, pursuing novel methods to manage skin disorders through localized, sustained protein delivery.

Cenna Biosciences

Grant in 2024
Cenna Biosciences is a biosciences company focused on the discovery and development of innovative drugs aimed at preventing and treating Alzheimer's disease. The company employs a proprietary mechanism to address the underlying cause of the disease, specifically targeting the inappropriate deposition of toxic ß-amyloid species in the brains of affected patients. Cenna Biosciences has identified a novel target and is actively developing several lead peptide compounds as disease-modifying candidates for Alzheimer's treatment.

Tiziana Life Sciences

Grant in 2024
Tiziana Life Sciences is a UK-based clinical-stage biotechnology company focused on discovering and developing novel molecules to treat diseases in oncology and immunology. Its pipeline includes Foralumab for autoimmune and inflammatory diseases, Milciclib for hepatocellular carcinoma, Anti IL-6r for severe COVID-19 symptoms, and StemPrintER for breast cancer diagnosis.

TransCode Therapeutics

Grant in 2024
TransCode Therapeutics, founded in 2016 and based in Boston, Massachusetts, is a biopharmaceutical company dedicated to discovering, developing, and commercializing innovative RNA therapeutics for treating metastatic cancer. Its lead therapeutic candidate targets an RNA molecule that drives metastatic disease across multiple tumor types.

Subtle Medical

Grant in 2024
Subtle Medical is a healthcare technology company that develops artificial‑intelligence software for magnetic resonance and positron emission tomography imaging. Its flagship products, SubtleMR and SubtlePET, are FDA‑cleared and CE‑marked tools that enhance image quality by reducing noise and sharpening detail, allowing scans to be performed faster and with lower radiation or contrast dose. The company’s deep‑learning algorithms integrate with any scanner without changing existing workflows, enabling imaging centers and hospitals to increase throughput and improve patient safety. Subtle Medical also offers a vendor‑agnostic AI platform that delivers analytics and support to clinical imaging providers. Founded in 2017 and headquartered in Menlo Park, California, the firm has received an NIH SBIR grant and an RSNA award for its GAD technology.

Precision Epigenomics

Grant in 2024
Precision Epigenomics, established in 2020 and based in Tucson, Arizona, specializes in molecular diagnostics for cancer. The company focuses on developing innovative molecular diagnostic assays, leveraging DNA methylation analysis, an epigenetic modification, to enhance cancer diagnosis and treatment. Their offerings aim to address unmet clinical needs, aiding clinicians in improved patient management.

Ensysce Biosciences

Grant in 2024
Ensysce Biosciences is a clinical-stage biotechnology company developing safer prescription drugs using proprietary platforms. It focuses on creating abuse-resistant opioids and overdose-protection products to reduce addiction risks and accidental overdoses associated with traditional opioids.

Marker Therapeutics

Grant in 2024
Marker Therapeutics is a clinical-stage immuno-oncology company developing adoptive non-gene modified T cell therapies for treating hematologic malignancies. Its MultiTAA technology selectively expands non-engineered T cells to target and kill tumor cells expressing multiple tumor-associated antigens, preventing immune escape.

University of Arkansas for Medical Sciences

Grant in 2024
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Immunovia

Grant in 2024
Immunovia is a diagnostics company focused on the early detection of pancreatic cancer and other complex diseases. It develops and commercializes innovative diagnostic tools using its proprietary technology platform, IMMray, which is based on antibody microarray analysis. The company conducts clinical trials and validation studies to ensure the accuracy and reliability of its tests. By collaborating with medical institutions and research centers worldwide, Immunovia aims to bring its diagnostic solutions to market, significantly impacting the treatment and management of pancreatic cancer and potentially improving survival rates. Its approach to utilizing blood-based biomarkers may also enable early detection strategies for other cancers and autoimmune diseases.

Anebulo Pharmaceuticals

Grant in 2024
Anebulo Pharmaceuticals is a clinical-stage biotechnology company focused on developing therapies for cannabinoid overdose and substance addiction. Its lead candidate, ANEB-001, is designed to reverse the effects of cannabinoid overdose within about one hour of administration. Early clinical data indicate rapid absorption and tolerability, with weight loss observed potentially linked to central cannabinoid receptor type 1 antagonism. The company aims to address acute overdose symptoms such as sedation, anxiety, panic, and psychosis by restoring balance to the endocannabinoid system.

Arkansas Children's Research Institute

Grant in 2024
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

Weill Cornell Medicine

Grant in 2024
Weill Cornell Medicine is a renowned academic medical center dedicated to excellence in patient care, scientific discovery, and educating future physicians. With over 300 IT professionals supporting more than 10,000 users across its institutions, it offers comprehensive technology services, including infrastructure management, security, networking, software development, and innovative solutions for clinical and research projects.

Metabolon

Grant in 2024
Metabolon develops metabolomics-based platforms and clinical diagnostic tests for early disease detection and precision medicine. It offers blood tests like QUANTOSE IR and QUANTOSE IGT, and Meta IMD for inherited metabolic disorders. The company serves various sectors including academia, biotech/pharmaceuticals, and precision medicine. It has strategic partnerships with major pharmaceutical companies and other industries.

Ensysce Biosciences

Grant in 2024
Ensysce Biosciences is a clinical-stage biotechnology company developing safer prescription drugs using proprietary platforms. It focuses on creating abuse-resistant opioids and overdose-protection products to reduce addiction risks and accidental overdoses associated with traditional opioids.

Arkansas Children's Research Institute

Grant in 2024
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

University of Arkansas for Medical Sciences

Grant in 2024
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Cincinnati Children’s

Grant in 2024
Cincinnati Children’s Hospital Medical Center is a leading institution dedicated to improving child health, attracting patients and families both regionally and internationally. Recognized for its expertise, the hospital serves as a referral center for complex surgical procedures and treatments for rare pediatric diseases. The center is committed to advancing pediatric medicine by discovering innovative and effective treatment methods, solidifying its reputation as one of the foremost facilities for pediatric care globally.

Lamassu Pharma

Grant in 2024
Lamassu Pharma is a biotech startup developing small-molecule therapies for severe acute pancreatitis, with a lead candidate developed at Mayo Clinic that has shown strong preclinical results in reducing mortality and morbidity. The company is advancing this compound through safety testing in preparation for definitive clinical trials, aiming to deliver life-saving treatments to patients. In addition, Lamassu develops other small-molecule therapeutics targeting urgent medical needs, including potential cancer treatments, pursuing multiple candidates through clinical development. The organization emphasizes a patient-centric, evidence-based research approach to accelerate translation of science into therapies for unmet medical needs.

University of Arkansas for Medical Sciences

Grant in 2024
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

University of Arkansas for Medical Sciences

Grant in 2023
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

The Stark Neurosciences Research Institute

Grant in 2023
The Stark Neurosciences Research Institute is dedicated to improving outcomes for persons suffering from disorders of the nervous system.

Hillhurst Biopharmaceuticals

Grant in 2023
Hillhurst Biopharmaceuticals specializes in developing innovative, liquid therapeutic gases for treating sickle cell disease. Their core technology enables the oral delivery of low-dose carbon monoxide, targeting the protective heme oxygenase system to reduce inflammation, prevent cell death, and halt hemoglobin polymerization. This approach addresses challenges associated with traditional inhaled gas therapies, such as caregiver exposure and imprecise dosing, ensuring accurate and safe administration.

Center for HIV Identification, Prevention, and Treatment Services

Grant in 2023
Center for HIV Identification, Prevention, and Treatment Services is a research organisation that conducts HIV research. They offers customer support through email and phone contact.

L2P Research

Grant in 2023
L2P Research Labs is a preclinical contract research organization (CRO) that specializes in providing comprehensive research and development support. The company offers a range of preclinical and toxicology services, utilizing advanced technologies such as quantitative whole-body animal imaging, small animal ultrasound, MRI, and CT scans. L2P Research Labs also provides proprietary orthotopic and metastatic tumor models, enabling researchers to access a complete suite of research services tailored to their needs. Through its innovative approaches and state-of-the-art facilities, the company supports the advancement of scientific research in the fields of medicine and drug development.

Rational Vaccines

Grant in 2023
Rational Vaccines is a biotechnology company focused on developing vaccines for herpes simplex virus (HSV) and related diseases. It aims to revolutionize treatment, prevention, and diagnosis by creating rationally engineered, live-attenuated viral vaccines.

Magnasense

Grant in 2023
Founded in Finland in 2003, Magnasense specializes in developing and manufacturing lateral flow tests for various applications. These include human health, environmental analysis, and veterinary testing. The company's innovative magnetic labeling technique enables quantitative measurements, enhancing reliability and sensitivity. Magnasense offers a Pilot Feasibility test service and operates as a subsidiary of LifeAssays AB.

Clene Nanomedicine

Grant in 2023
Clene Nanomedicine, established in 2012 and headquartered in Salt Lake City, Utah, is a clinical-stage biopharmaceutical company dedicated to developing innovative therapeutics for neurodegenerative diseases. The company has pioneered a unique nanotechnology drug platform that enables the creation of orally-administered neurotherapeutic drugs. This technology, known as Clean-Surface Nanosuspension, produces clean-surface nanocrystal medicines and serves as a foundation for a pipeline of new drug candidates aimed at addressing various diseases with significant unmet medical needs. Clene Nanomedicine's primary focus areas include demyelinating disorders and oncology.

Actinium Pharmaceuticals

Grant in 2023
Actinium Pharmaceuticals is a biopharmaceutical company focused on developing and commercializing therapies for life-threatening diseases using its alpha particle immunotherapy platform. Its lead product candidates include Iomab-B, in Phase III trials as an induction agent for elderly AML patients prior to bone marrow transplant, and Actimab-A, in Phase II trials for newly diagnosed AML patients aged 60 and over.

Neurodon

Grant in 2023
Neurodon Corporation is a biopharmaceutical company focused on discovering and developing disease-modifying therapeutic candidates for intractable diseases. Established in 2019 and headquartered in Crown Point, Indiana, Neurodon specializes in molecular therapies that address endoplasmic reticulum (ER) stress, a significant factor in cell dysfunction and death. The company's innovative approach aims to restore calcium homeostasis through first-in-class modulators, addressing conditions such as Alzheimer's disease, Parkinson's disease, Huntington's disease, diabetes, and other rare diseases. Neurodon has made significant progress, with two candidates currently in IND-enabling studies and plans to enter clinical trials in 2025. The company has raised over $11 million through various funding sources, including state and federal grants, partnerships, and angel investments, and is actively seeking additional funding to support its first human studies for diabetes and rare disease programs.

SpineX

Grant in 2023
SpineX develops and tests neuromodulation technologies for non-invasive devices that aid recovery in individuals with neurological conditions such as strokes, spinal cord injuries, multiple sclerosis, and cerebral palsy. Their focus is on restoring bladder, bowel, respiration, sexual, and sensorimotor functions.

South Rampart Pharma

Grant in 2023
South Rampart Pharma is a clinical-stage biotechnology company focused on safer pain therapies. It develops synthesized, non-opioid and non-liver-toxic molecules that modulate pain signaling in the brain's periaqueductal gray (PAG) region, aiming to provide effective analgesia with reduced abuse potential and liver toxicity compared with traditional opioids. The company’s approach seeks to address key safety and tolerability challenges in current pain medicines while delivering meaningful relief for patients.

Glyphic Biotechnologies

Grant in 2023
Glyphic Biotechnologies is a biotechnology company focused on developing an advanced protein sequencing platform that aims to enhance the understanding of human biology and diseases. Recognizing that while DNA offers valuable biological insights, it is proteins that provide critical information about bodily functions, Glyphic Biotechnologies is creating a next-generation sequencing technology. This innovative platform is designed to increase binding affinity and improve consistency, ultimately facilitating the creation of personalized and precision cancer vaccines for diverse patient populations. By enabling scientists and researchers to perform single-molecule, massively parallel protein sequencing, the company aims to support the development of novel therapeutics and diagnostics, paving the way for significant advancements in biomedical research and healthcare.

Subtle Medical

Grant in 2023
Subtle Medical is a healthcare technology company that develops artificial‑intelligence software for magnetic resonance and positron emission tomography imaging. Its flagship products, SubtleMR and SubtlePET, are FDA‑cleared and CE‑marked tools that enhance image quality by reducing noise and sharpening detail, allowing scans to be performed faster and with lower radiation or contrast dose. The company’s deep‑learning algorithms integrate with any scanner without changing existing workflows, enabling imaging centers and hospitals to increase throughput and improve patient safety. Subtle Medical also offers a vendor‑agnostic AI platform that delivers analytics and support to clinical imaging providers. Founded in 2017 and headquartered in Menlo Park, California, the firm has received an NIH SBIR grant and an RSNA award for its GAD technology.

Glyphic Biotechnologies

Grant in 2023
Glyphic Biotechnologies is a biotechnology company focused on developing an advanced protein sequencing platform that aims to enhance the understanding of human biology and diseases. Recognizing that while DNA offers valuable biological insights, it is proteins that provide critical information about bodily functions, Glyphic Biotechnologies is creating a next-generation sequencing technology. This innovative platform is designed to increase binding affinity and improve consistency, ultimately facilitating the creation of personalized and precision cancer vaccines for diverse patient populations. By enabling scientists and researchers to perform single-molecule, massively parallel protein sequencing, the company aims to support the development of novel therapeutics and diagnostics, paving the way for significant advancements in biomedical research and healthcare.

Buck Institute

Grant in 2023
The Buck Institute is the nation’s first independent research facility focused solely on understanding the connection between aging and chronic disease. Their mission is to increase the healthy years of life. At the Buck Institute, world-class scientists work in a uniquely collaborative environment to understand how normal aging contributes to the development of conditions specifically associated with getting older such as Alzheimer’s and Parkinson’s diseases, cancer, stroke, osteoporosis, heart disease, diabetes, macular degeneration and glaucoma. Their interdisciplinary approach brings scientists from disparate fields together to develop diagnostic tests and treatments to prevent or delay these maladies. The stakes have never been higher. While it’s true that people are living longer, those “extra” years are often marked by disability and pain. In addition to personal hardship, there is also a cost to society. The financial burden of treating the chronic diseases of aging is expected to rise steadily as Baby Boomers get older. There is an urgency to Their mission.

University of Oklahoma - Health Sciences Center

Grant in 2023
University of Oklahoma Health Sciences Center, as a comprehensive academic health center, is to educate students, residents, and other trainees in professional and graduate programs to become Oklahoma’s future team of healthcare leaders, clinicians, researchers, and educators; to advance distinctive basic, translational, clinical, and population research; to innovate and commercialize discoveries; and to deliver exceptional patient care across the full breadth of adult, women’s, and children’s specialties.

Morehouse School of Medicine

Grant in 2023
Founded in 1975, Morehouse School of Medicine is a private medical school located in Atlanta, Georgia. It offers a Doctor of Medicine (MD) program with specializations in Family Medicine, Internal Medicine, Obstetrics and Gynecology, Pediatrics, Psychiatry and Behavioral Sciences, and Surgery. The school also provides master's degrees in Public Health and Biomedical Sciences. Morehouse is committed to educating minority students and reducing health disparities.

Inherent Biosciences

Grant in 2023
Inherent Biosciences is a molecular diagnostics company focused on transforming the traditional trial and error approach in medicine. The company leverages its innovative epigenetic medicine platform to address various health challenges by identifying gene dysregulation and its associated pathways. By translating biological insights into actionable information, Inherent Biosciences aims to enhance treatment strategies for conditions such as pain, infertility, embryo quality, autism, rheumatoid arthritis, psoriatic arthritis, fetal heart disease, and COVID-19. This approach not only guides healthcare professionals in managing complex diseases but also seeks to provide personalized insights that empower patients in their health journeys.

Glyphic Biotechnologies

Grant in 2023
Glyphic Biotechnologies is a biotechnology company focused on developing an advanced protein sequencing platform that aims to enhance the understanding of human biology and diseases. Recognizing that while DNA offers valuable biological insights, it is proteins that provide critical information about bodily functions, Glyphic Biotechnologies is creating a next-generation sequencing technology. This innovative platform is designed to increase binding affinity and improve consistency, ultimately facilitating the creation of personalized and precision cancer vaccines for diverse patient populations. By enabling scientists and researchers to perform single-molecule, massively parallel protein sequencing, the company aims to support the development of novel therapeutics and diagnostics, paving the way for significant advancements in biomedical research and healthcare.

Applied BioMath

Grant in 2023
Applied BioMath, LLC, established in 2013 and headquartered in Concord, Massachusetts, specializes in systems biology and pharmacology services aimed at accelerating drug research and development for biotechnology and pharmaceutical companies. The company employs advanced mathematical modeling and simulation techniques to provide predictive guidance and insights throughout the drug discovery process. Its offerings include pathway model development, target and biomarker discovery, and feasibility assessments for various drug targets. Additionally, Applied BioMath conducts analyses of competitor compounds and projects drug properties and dosing for clinical phases. The firm utilizes proprietary algorithms and high-performance computational biology to optimize decision-making and mitigate risks associated with late-stage attrition in drug development. With additional offices in Cambridge and Oakland, Applied BioMath collaborates strategically with industry leaders such as Sanofi and Xilio Therapeutics to enhance its service offerings.

iMetabolic Biopharma

Grant in 2023
iMetabolic Biopharma is an early-stage precision medicine drug development company focused on obesity-related diseases. It develops therapeutics using its iPlatform technology, a platform designed to accelerate drug discovery and reduce development costs, enabling potential life-saving solutions to reach the clinic faster and more affordably.

Opsin Biotherapeutics

Grant in 2023
Opsin Biotherapeutics specializes in the development of gene therapies based on opsins, a class of light-sensitive proteins. The company's primary focus is to create a pipeline of treatments for pain management, aiming to provide effective alternatives to opioids.

University of Arkansas for Medical Sciences

Grant in 2023
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Kintara Therapeutics

Grant in 2023
Kintara Therapeutics is a clinical-stage cancer drug development company focused on creating and advancing therapies for difficult-to-treat cancers. Its late-stage product candidates include VAL-083, a DNA-targeting chemotherapeutic agent in Phase III-ready development for drug-resistant solid tumors such as glioblastoma multiforme, and REM-001, a photodynamic therapy for cutaneous metastatic breast cancer. The company pursues strategic collaborations to expand access, including a partnership with Guangxi Wuzhou Pharmaceutical to manufacture and sell VAL-083 in China. By focusing on streamlined, high-need cancer indications, Kintara aims to bring novel treatments to patients with limited options.

Marker Therapeutics

Grant in 2023
Marker Therapeutics is a clinical-stage immuno-oncology company developing adoptive non-gene modified T cell therapies for treating hematologic malignancies. Its MultiTAA technology selectively expands non-engineered T cells to target and kill tumor cells expressing multiple tumor-associated antigens, preventing immune escape.

The University of Texas MD Anderson Cancer Center

Grant in 2023
The University of Texas MD Anderson Cancer Center is a leading institution dedicated exclusively to cancer patient care, research, education, and prevention. Located in the Texas Medical Center in Houston, Texas, it was established as one of the original three comprehensive cancer centers under the National Cancer Act of 1971. MD Anderson serves as both a degree-granting academic institution and a specialized cancer treatment facility. It is affiliated with two prominent medical schools: The University of Texas Medical School at Houston and Baylor College of Medicine. Renowned for its exceptional cancer care, MD Anderson has consistently ranked among the top cancer hospitals in the United States, earning the No. 1 position in U.S. News & World Report's "Best Hospitals" survey for ten of the past twelve years. The center is widely recognized for its commitment to advancing cancer treatment and improving patient outcomes.

University of Alabama at Birmingham

Grant in 2023
The University of Alabama at Birmingham (UAB), established in 1969, is a distinguished institution located in Birmingham, Alabama. It offers a diverse range of over 130 undergraduate and graduate programs, including degrees in the arts, sciences, business, education, engineering, and public health. UAB is particularly renowned for its medical school, which encompasses one of the largest university medical centers in the United States. The university has produced numerous scholars and award recipients, such as Fulbright, Rhodes, and Truman scholars, reflecting the high caliber of its education. Student life at UAB is dynamic, featuring more than 150 student organizations, an active Greek community, and a top-ranking recreation and fitness center, alongside year-round intramural sports. Most students reside in on-campus housing, and UAB provides financial aid and departmental fellowships to support those in need of tuition assistance. Through its commitment to education, research, and community service, UAB addresses both local and global challenges while fostering a culture of discovery and innovation.

Shirley Ryan AbilityLab

Grant in 2023
Shirley Ryan AbilityLab is a translational research hospital. Their services include spinal cord injury recovery, brain injury recovery, COVID recovery, pediatric and adolescent rehabilitation, nursing, cancer rehabilitation, limb loss and impairment, and pain management.

Domus Diagnostics

Grant in 2023
Founded in 2021, Domus Diagnostics specializes in respiratory disease home testing services via its care diagnostics platform. The company offers affordable, user-friendly, and accurate testing kits designed to address infectious disease outbreaks promptly.

Aphios

Grant in 2023
Aphios Corporation is a biotechnology company based in Woburn, Massachusetts, specializing in drug delivery platforms and the development of quality-of-life medicines. The company focuses on enhancing drug discovery and manufacturing through its innovative biotechnology and nanotechnology solutions. Aphios offers a range of therapeutic products aimed at health maintenance, disease prevention, and the treatment of various conditions, including cancers, infectious diseases, and central nervous system disorders. Notable products include Zindol, a ginger-based product, and various formulations of Taxotere for cancer treatment, which aim to improve oral bioavailability and target specific cancer cells. In addition to its therapeutic offerings, Aphios develops advanced technologies such as SuperFluids for pharmaceutical manufacturing and virology testing services, contributing to the safety and efficacy of drug therapies. Founded in 1993, Aphios continues to push the boundaries of medical science with its focus on innovative solutions for complex health challenges.

Health 360x

Grant in 2023
Health 360x brings together patients, clinicians, and researchers to enhance the health of neglected groups. Health 360x is changing clinical research through point-of-care access for patients and providers in non-academic practices that mostly serve African Americans and other patients who have historically been underrepresented in corporate and NIH clinical trials.

Washington University School Of Medicine

Grant in 2023
Washington University School of Medicine is the medical school of Washington University in St. Louis.A leader in medical research, teaching and patient care, Washington University School of Medicine is currently ranked fourth in the nation by U.S. News & World Report. The School’s 2,100 employed and volunteer faculty physicians and clinicians -- known as Washington University Physicians -- are also medical staff members of Barnes-Jewish and St. Louis Children’s hospitals. The clinical practice group provides care to more than 430,000 children and adults at 49 clinical sites annually. Together, the institutions located on the Washington University Medical Center campus employ more than 21,000 clinicians, scientists, residents, fellows, administrators and support staff.

University of Alabama at Birmingham

Grant in 2023
The University of Alabama at Birmingham (UAB), established in 1969, is a distinguished institution located in Birmingham, Alabama. It offers a diverse range of over 130 undergraduate and graduate programs, including degrees in the arts, sciences, business, education, engineering, and public health. UAB is particularly renowned for its medical school, which encompasses one of the largest university medical centers in the United States. The university has produced numerous scholars and award recipients, such as Fulbright, Rhodes, and Truman scholars, reflecting the high caliber of its education. Student life at UAB is dynamic, featuring more than 150 student organizations, an active Greek community, and a top-ranking recreation and fitness center, alongside year-round intramural sports. Most students reside in on-campus housing, and UAB provides financial aid and departmental fellowships to support those in need of tuition assistance. Through its commitment to education, research, and community service, UAB addresses both local and global challenges while fostering a culture of discovery and innovation.

Scene Health

Grant in 2023
Scene Health enhances medication adherence through its innovative video-based platform. It combines personalized coaching, education, and motivational content to engage patients, care teams, and families. The mobile app facilitates daily video check-ins with pharmacists, nurses, and health coaches, improving medication adherence for chronic and infectious diseases.

Feinstein Institute for Medical Research

Grant in 2023
Feinstein Institute For Medical Research is the research arm of Northwell Health, the largest health care provider and private employer in New York State. Home to 50 research labs, 3,000 clinical research studies and 5,000 researchers and staff, the Feinstein Institutes raises the standard of medical innovation through its five institutes of behavioral science, bioelectronic medicine, cancer, health innovations and outcomes, and molecular medicine. We make breakthroughs in genetics, oncology, brain research, mental health, autoimmunity, and are the global scientific leader in bioelectronic medicine – a new field of science that has the potential to revolutionize medicine.

TransCode Therapeutics

Grant in 2023
TransCode Therapeutics, founded in 2016 and based in Boston, Massachusetts, is a biopharmaceutical company dedicated to discovering, developing, and commercializing innovative RNA therapeutics for treating metastatic cancer. Its lead therapeutic candidate targets an RNA molecule that drives metastatic disease across multiple tumor types.

Oncospherix

Grant in 2023
OncoSpherix, Inc., based in Atlanta, Ga, is a pre-clinical stage oncology drug development company that is advancing a proprietary platform of first-in-class small molecule therapeutics that are designed to improve the quality of life and survival for people with many forms of cancer by targeting a common feature of solid tumors: the activation of hypoxia inducible factor-1 (HIF-1). Nearly all solid cancers grow faster than their blood supply, leading to regions of low oxygen in the tumors and HIF activation. The HIFs in turn induce the expression of over 100 genes that help tumor cells survive and spread. OncoSpherix has several classes of small molecules that block activation of HIF-1 through novel mechanisms. OncoSpherix’s lead clinical candiate has been shown in mouse models to reduce primary tumor growth, inhibit metastases, and prolong survival in many types of cancer (glioblastoma, pancreatic cancer, uveal melanoma, lung cancer, breast cancer). Importantly, the agents are well tolerated and can be combined with therapeutics that work in well oxygenated regions of cancers, leading to dramatically enhanced cancer control.

Arkansas Children's Research Institute

Grant in 2023
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

Oklahoma Medical Research Foundation

Grant in 2023
The Oklahoma Medical Research Foundation (OMRF) is a non-profit biomedical research institute dedicated to understanding and treating various devastating illnesses, including Alzheimer's, heart disease, lupus, multiple sclerosis, and cancer. It operates a research facility, providing services and access to resources that facilitate drug discoveries and improve patient care.

Chemeleon

Grant in 2023
Chemeleon is a company that has developed an innovative platform technology for rapid and affordable diagnostics capable of detecting a wide array of analytes, including drugs, proteins, and viruses. Their proprietary in vitro diagnostic format delivers a colorimetric readout within minutes, visible to the naked eye, and does not require reagents, instruments, or specialized training. This decentralized testing approach empowers clinicians to extend point-of-care diagnostics and allows individuals to self-administer tests at the point of need. Chemeleon's diagnostics utilize highly selective molecular receptors combined with colorimetric nanomaterial reporters, facilitating immediate and actionable diagnoses that can significantly improve patient outcomes while reducing healthcare costs. Notably, the company developed a diagnostic for detecting beta-2-transferrin, a biomarker for Cerebrospinal Fluid leaks, resulting in substantial reductions in morbidity and healthcare expenses. With a focus on providing specificity and selectivity comparable to lab-based tests but in a fraction of the time and cost, Chemeleon's technology stands to transform healthcare accessibility, especially in resource-limited environments.

Linshom

Grant in 2022
Linshom develops continuous respiratory monitoring solutions for bedside and home use, providing an operating-room quality respiratory profile including tidal volume through wearable, FDA-cleared sensors. The system enables continuous predictive monitoring of respiration, delivering early warnings of respiratory decline to help reduce rapid-response activations, rescue events, and ICU transfers. By capturing respiration data and relative tidal volume at the point of care, Linshom addresses an unmet clinical need with actionable insights for clinicians.

Aptinyx

Grant in 2022
Aptinyx Inc. is a clinical-stage biopharmaceutical company based in Evanston, Illinois, that specializes in discovering and developing innovative therapies for disorders of the brain and nervous system. Founded in 2015, the company focuses on proprietary synthetic small molecules that modulate the NMDA receptor, enhancing nerve cell communication. Aptinyx's pipeline includes NYX-2925, which is in Phase II clinical development for painful diabetic peripheral neuropathy and fibromyalgia, and NYX-783, currently in Phase I trials for post-traumatic stress disorder. Additionally, NYX-458, another NMDA receptor modulator, is undergoing Phase I studies aimed at treating cognitive impairment associated with Parkinson's disease. The company also collaborates with Allergan plc to develop a compound for major depressive disorder, highlighting its commitment to addressing significant unmet medical needs in the central nervous system arena.

Feinstein Institute for Medical Research

Grant in 2022
Feinstein Institute For Medical Research is the research arm of Northwell Health, the largest health care provider and private employer in New York State. Home to 50 research labs, 3,000 clinical research studies and 5,000 researchers and staff, the Feinstein Institutes raises the standard of medical innovation through its five institutes of behavioral science, bioelectronic medicine, cancer, health innovations and outcomes, and molecular medicine. We make breakthroughs in genetics, oncology, brain research, mental health, autoimmunity, and are the global scientific leader in bioelectronic medicine – a new field of science that has the potential to revolutionize medicine.

University of Arkansas for Medical Sciences

Grant in 2022
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Neurovations

Grant in 2022
Neurovations, a patient care and innovation company, was founded in 1992 by CEO Dr. Eric Grigsby. Today, Neurovations is a national leader in medical device and pharmaceutical innovation, clinical research, and a world-class education program focusing in pain and neuroscience. Dr. Grigsby is deeply connected to the healthcare community through our non-profit HealthRoots Foundation. Our unwavering mission is to inspire hope and to contribute to the health and well-being of our patients and communities through integrated clinical practice, research, and education.

Georgia CTSA

Grant in 2022
The Georgia Clinical & Translational Science Alliance (Georgia CTSA) is an inter-institutional magnet that concentrates basic, translational, and clinical research investigators, community clinicians, professional societies, and industry collaborators in dynamic clinical and translational research projects. Emory engaged three of its close academic partners - Morehouse School of Medicine (MSM), Georgia Institute of Technology (Georgia Tech), and the University of Georgia (UGA) - to form the Georgia CTSA. This partnership, a strategic multi-institutional alliance, offers compelling, unique, and synergistic advantages to research and patients statewide. Emory is a national leader in healthcare and biomedical research as well as an outstanding leader in clinical and translational research training and education. Morehouse School of Medicine is a nationally recognized historically black institution that brings ethnic diversity to biomedical research, addresses health disparities through successful community engagement research, and serves as a pipeline for training minority researchers. Georgia Tech is a national leader in biomedical engineering and the application of innovative systems engineering to healthcare solutions. UGA has a proven track record in outstanding basic and translational research and, as the State’s land-grant institution, offers a robust statewide network that enhances community outreach, service, and research. These institutions extend their current partnerships in healthcare, education, and cutting-edge interdisciplinary research to synergize Georgia CTSA. Created in 2017 as one of a national consortium striving to improve the way biomedical research is conducted across the country. The consortium, funded through the National Center for Advancing Translational Sciences, part of the National Institutes of Health's Clinical and Translational Science Awards (CTSA), shares a common vision to translate laboratory discoveries into treatments for patients, engage communities in clinical research efforts and train the next generation of clinical investigators.

Indiana University School of Medicine

Grant in 2022
The Indiana University School of Medicine is the largest medical school in the United States. The IU School of Medicine, which is made up of five fundamental science departments and twenty clinical departments, provides superior training for students interested in pursuing a medical degree. The school launched a new medical education curriculum with the Class of 2020 that better represents the modern U.S. health care environment and delivery methods, preparing students to practice medicine in a team-based, multidisciplinary setting.

Allen Institute for Brain Science

Grant in 2022
Allen Institute for Brain Science is a non-profit medical research organization dedicated to understanding the complexities of bioscience. The organization encompasses three entities, the Allen Institute for Brain Science, Allen Institute for Cell Science, and Paul G. Allen Frontiers Group. Its mission is to accelerate the understanding of how the brain works in health and disease. It creates useful public resources, drive technological and analytical advances, and discover fundamental brain properties through integration of experiments using a big science, team science, and open science approach. Allen Institute for Brain Science was founded on 2003 and is based in Seattle, Washington.

Wake Forest School of Medicine

Grant in 2022
Wake Forest School of Medicine is an educational institution based in Winston Salem, North Carolina, founded in 1902. It specializes in biomedical research and offers primary care education and training, with students gaining hands-on experience with patients from their first week of medical school. The school also provides tertiary care, which is crucial for a research and teaching hospital. Wake Forest School of Medicine has a nationally recognized research program, attracting over $400 million in extramural funding annually. It educates nearly 1,900 students and fellows, including physicians, basic scientists, and allied clinical professionals.

Arkana Laboratories

Grant in 2022
Arkana Laboratories offers renal pathology, neuropathology and testing, apol1, and biopharmaceutical services. It is a provider of esoteric pathologic services and a centre for pathology focused on improving care for patients. For inquiries, email, telephone numbers, and physical addresses are available on their website.

Evaxion Biotech

Grant in 2022
Evaxion Biotech is a clinical-stage company leveraging AI-immunology™ technology to decode the human immune system, developing novel immunotherapies for cancer and infectious diseases. Its pipeline includes three patient-specific cancer therapies in Phase I/IIa trials and vaccines targeting bacterial and viral infections.

Glyphic Biotechnologies

Grant in 2022
Glyphic Biotechnologies is a biotechnology company focused on developing an advanced protein sequencing platform that aims to enhance the understanding of human biology and diseases. Recognizing that while DNA offers valuable biological insights, it is proteins that provide critical information about bodily functions, Glyphic Biotechnologies is creating a next-generation sequencing technology. This innovative platform is designed to increase binding affinity and improve consistency, ultimately facilitating the creation of personalized and precision cancer vaccines for diverse patient populations. By enabling scientists and researchers to perform single-molecule, massively parallel protein sequencing, the company aims to support the development of novel therapeutics and diagnostics, paving the way for significant advancements in biomedical research and healthcare.

Oligomerix

Grant in 2022
Founded in 2006, Oligomerix is a biopharmaceutical company dedicated to developing therapeutics for Alzheimer's and related neurodegenerative diseases. It focuses on tau oligomer and tau protease inhibitor programs for small molecule drug discovery, and develops antibody fragments for tau oligomers as biomarkers.

Arkansas Children's Research Institute

Grant in 2022
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

Feinstein Institute for Medical Research

Grant in 2022
Feinstein Institute For Medical Research is the research arm of Northwell Health, the largest health care provider and private employer in New York State. Home to 50 research labs, 3,000 clinical research studies and 5,000 researchers and staff, the Feinstein Institutes raises the standard of medical innovation through its five institutes of behavioral science, bioelectronic medicine, cancer, health innovations and outcomes, and molecular medicine. We make breakthroughs in genetics, oncology, brain research, mental health, autoimmunity, and are the global scientific leader in bioelectronic medicine – a new field of science that has the potential to revolutionize medicine.

Oklahoma Medical Research Foundation

Grant in 2022
The Oklahoma Medical Research Foundation (OMRF) is a non-profit biomedical research institute dedicated to understanding and treating various devastating illnesses, including Alzheimer's, heart disease, lupus, multiple sclerosis, and cancer. It operates a research facility, providing services and access to resources that facilitate drug discoveries and improve patient care.

Eliaz Therapeutics

Grant in 2022
Eliaz Therapeutics is focused on developing innovative medical devices aimed at treating life-threatening diseases that are currently difficult to manage. The company's flagship device utilizes a patented apheresis column designed to selectively remove galectin-3 from human blood. This device targets both bound and free galectin-3, a protein linked to various serious health conditions, including diabetes, chronic kidney disease, organ fibrosis, and cancer. By efficiently eliminating galectin-3 from the bloodstream, the device offers a less invasive treatment option with fewer side effects compared to traditional therapies. Its design leverages a proprietary capturing molecule and is compatible with existing hospital systems, facilitating its adoption in clinical settings.

Reliant Glycosciences

Grant in 2022
Reliant Glycosciences is a biotechnology company dedicated to developing diagnostic and prognostic tools specifically for patients with IgA nephropathy. The company focuses on creating assays that identify biomarkers associated with this condition, which possess diagnostic and prognostic value. By characterizing disease-specific biomarkers, Reliant Glycosciences aims to facilitate the development and testing of innovative, targeted therapies for IgA nephropathy. This approach not only supports the advancement of transformative treatments but also enhances the overall understanding of the disease, ultimately benefiting patients affected by this condition.

Immunicom

Grant in 2022
Founded in 2013, Immunicom specializes in developing innovative, non-pharmaceutical immunotherapy treatments for cancer, inflammatory diseases, and autoimmune disorders. The company's core product is a therapeutic device designed to filter blood and directly target various types of cancer, potentially enhancing the effects of other treatments with fewer side effects.

AVM Biotechnology

Grant in 2022
AVM Biotechnology is a Seattle-based clinical-stage biotechnology company focused on regenerative medicine, oncology, and human biologics. It develops stem cell–based technologies and biologic therapies, including in-house compounds to modulate stem cell binding for enhanced organ regeneration and immune recovery, as well as platforms for personalized biologics that reduce immunogenicity and improve biodistribution. The Boutique Biologics platform supports patient-specific manufacturing approaches, while the Better Biologics platform provides methods for large-scale production of human biologics and aims to overcome resistance seen with non-human cell systems. The company also pursues preclinical programs, including repurposed small molecules and antibodies, and aims to provide cell lines for large-scale biologic production and patient-specific cell lines for personalized medicine. Led by oncology and immunology experts, AVM Biotechnology concentrates on translating stem cell and immune-based strategies to treat cancer, autoimmune diseases, and infectious diseases.

NovoMedix

Grant in 2022
NovoMedix is a biotechnology company focused on developing novel orally available small molecules to address fibrotic disorders and certain cancer types. The company utilizes a proprietary technology platform that includes a library of small-molecule inhibitors, which have demonstrated significant efficacy in animal models for both fibrosis and cancer. Notably, some of these compounds co-target pathways that offer cardioprotective benefits and enhance the effectiveness of standard chemotherapies for triple negative breast cancer. This dual action aims to improve patient responses to treatment while significantly reducing the cardiotoxic effects commonly associated with chemotherapies, such as doxorubicin. As cardiovascular disease is a leading cause of death among breast cancer survivors, NovoMedix's approach prioritizes long-term patient health by addressing both cancer and associated heart risks. The company is working towards initiating IND enabling studies for its lead candidate, with the objective of delivering a safe and effective therapy to patients as soon as possible.

Modality.AI

Grant in 2022
Modality.AI, Inc. is a healthcare technology company based in San Francisco, California, founded in 2018. It specializes in AI-powered solutions that enhance the efficiency of clinical trials for neurological and mental health therapies. The company's platform utilizes conversational AI to engage patients through naturalistic spoken interaction, allowing for continuous health assessments anytime and anywhere. By analyzing multimodal data, including audio-visual biomarkers, Modality.AI provides objective measures that correlate with clinical outcomes. This innovative approach enables pharmaceutical companies to conduct self-driven assessments and improve the monitoring of health conditions, ultimately facilitating more effective clinical trials.

University of Arkansas for Medical Sciences

Grant in 2022
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Benaroya Research Institute

Grant in 2022
Benaroya Research Institute at Virginia Mason (BRI) is one of the few research institutes in the world dedicated to discovering causes and cures to eliminate autoimmune and immune system diseases. At BRI, their scientists aren’t focused on eliminating one or two autoimmune diseases—they’re taking on all 80. Because autoimmune diseases are connected, so is the way they’re fighting them. They're applying the breakthroughs they make against individual autoimmune diseases to make progress against them all. Through collaboration and cooperation between researchers, across clinical trials and with other institutions, they connect laboratory research to clinical trials and translate discoveries to real-life applications. As a world leader in scientific innovation, they’re leveraging this progress to eliminate autoimmune and immune system diseases in the future. Their discoveries are also having significant impact on people living with autoimmune and immune system diseases today—by improving the ability to predict disease risk, facilitate treatment, decrease progression of these diseases and make related therapies safer and more effective.

Dascena

Grant in 2022
Dascena, Inc. is a healthcare technology company based in Oakland, California, that specializes in developing machine learning algorithms aimed at enhancing disease detection and improving patient care outcomes. Established in 2018, Dascena's flagship product, AlgoDiagnostics, autonomously processes electronic health record data to facilitate early intervention for conditions such as acute decompensation, sepsis, and acute kidney injury. The company focuses on addressing unmet healthcare needs through its innovative solutions in clinical decision support, point-of-care diagnostics, and biopharma companion diagnostics. By leveraging intensive clinical research, Dascena aims to enable clinical practitioners to make timely and accurate interventions, ultimately saving lives and enhancing the delivery of care.

Weill Cornell Medicine

Grant in 2022
Weill Cornell Medicine is a renowned academic medical center dedicated to excellence in patient care, scientific discovery, and educating future physicians. With over 300 IT professionals supporting more than 10,000 users across its institutions, it offers comprehensive technology services, including infrastructure management, security, networking, software development, and innovative solutions for clinical and research projects.

Genomenon

Grant in 2022
Genomenon, Inc. is a software development company based in Ann Arbor, Michigan, that specializes in tools for genetic diagnosis and discovery. Founded in 2014, it provides a suite of diagnostic and discovery solutions that enable physicians, researchers, and pharmaceutical companies to rapidly and accurately identify disease-causing variants from genomic sequencing data. The company’s flagship product, GENOMENON, automates the analysis of next-generation sequencing data, thereby enhancing decision-making processes in clinical settings and accelerating discoveries in genomics. With its focus on improving cancer diagnosis and treatment, Genomenon aims to support better patient outcomes through its innovative software solutions.

Meridian Bioscience

Grant in 2022
Meridian Bioscience is an integrated life science company that develops, manufactures, and distributes clinical diagnostic test kits for gastrointestinal, viral, respiratory, and parasitic infectious diseases. The company specializes in molecular and immunological reagents, providing tools that support the discovery and diagnosis of various medical conditions. In addition to diagnostic test kits, Meridian offers bulk antigens, antibodies, PCR and qPCR reagents, nucleotides, and bioresearch reagents, serving researchers and other diagnostic manufacturers. Moreover, the company engages in contract development and manufacturing of proteins and other biologicals under cGMP conditions, catering to biopharmaceutical and biotechnology firms involved in drug and vaccine research. Meridian operates through three segments: U.S. Diagnostics, European Diagnostics, and Life Science, emphasizing its commitment to enhancing healthcare outcomes through innovative solutions.
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