MedTech Innovator

INOPASE is a medical device company focused on developing wirelessly powered, closed-loop implantable neuromodulation systems. Currently, it specializes in the development of closed loop sacral neuromodulation for overactive bladder treatment and closed loop brain neuromodulation for epilepsy management.

Ortho-tag is a developer of innovative in-vivo platforms that facilitate the connection between digital health applications and implanted biosensors within the human body. The company's technologies focus on enhancing wireless communication with medical devices through proprietary transcutaneous volume conduction. This enables real-time data exchange, in-vivo storage, and the integration of nanodiagnostic and therapeutic functions in smart medical implants. By providing a comprehensive system for wireless communication and data management, Ortho-tag supports medical device developers in advancing the capabilities of healthcare technology.

Founded in 2015, Nanobiofab specializes in manufacturing smart, nanotech-based wearable healthcare devices for humans and pets. Its flagship product, iNose, detects and monitors skin vapor-print wirelessly via mobile phone, tracking fat burning rate, exercise effectiveness, and metabolic rate over time.

NXgenPort develops digital health technology for remote monitoring of cancer patients between chemotherapy visits. Its Smart Port device measures cell counts and heart function in vivo, alerting physicians to signs of infection and reducing hospitalizations. This data also improves patient outcomes and provides valuable insights for cancer researchers.

Healthcare is moving to the outpatient setting to save costs, but at home patients struggle with medication adherence and they are readmitted at alarming rates. Hospitals send 1.4 million patients home for 4-6 weeks to administer their own IV antibiotics every year. Twenty percent of patients on outpatient parenteral antimicrobial therapy (OPAT) are readmitted, each costing $80,000 on average. This is a $22.4 billion problem. Clinicians at the 12,200 home infusion providers in the US have no objective way to identify non-adherence to intervene and prevent readmissions. Rather, they call patients to detect non-adherence, which is time-consuming, inaccurate, and prone to reporting bias. They need a better tool than a phone to monitor adherence. The solution is HIVE’s patent pending CloudConnect smart catheter. CloudConnect is a reinvented IV line with a simple embedded mechanoelectrical sensor that detects when a medication source is connected. CloudConnect wirelessly sends this information to electronic medical records. HIVE’s value proposition is that clinicians can detect non-adherence in real time and make treatment decisions and prevent costly readmissions based on objective data. HIVE offers CloudConnect as an alternative to the need for clinicians to call every patient with standard IV lines.

CARI Health develops wearable remote medication monitors that attach to the skin and continuously transmit data about medication levels to the cloud, enabling clinicians to prescribe medications and monitor real-time exposure. The sensor-enabled system supports personalized dosing by facilitating safe titration of therapies with narrow therapeutic windows, potentially improving dosing precision and patient outcomes. The company was founded in 2015 and is based in San Diego, California.

Lazurite is a medical device company focused on wireless imaging and lighting technologies for minimally invasive surgery. It develops modular wireless camera and lighting platforms that remove wires and enhance operating room safety and efficiency. The product family includes ArthroFree, a fully wireless minimally invasive camera system for the operating room, and ORFree, a wireless mobile surgical camera platform, both enabled by the Meridiem light engine technology. These innovations aim to simplify the surgical setup, improve visualization, and enable greater maneuverability during procedures.

PyrAmes is a healthcare technology company that has created an innovative, paper-thin, flexible device for non-invasive blood pressure monitoring. This ultra low-power device is designed to deliver continuous and accurate blood pressure measurements wirelessly, making it suitable for patients of all ages, from newborns to seniors. PyrAmes aims to transform healthcare delivery by providing a platform that enables healthcare providers to conduct pain-free blood pressure monitoring, particularly benefiting vulnerable populations such as neonates.

Synotrac develops an implantable sensor technology that monitors infection post-joint surgery. The device detects infections in real-time by analyzing the body's immune response, enabling earlier detection compared to traditional methods.

Nanowear, Inc. is a technology company specializing in textile-based nanosensor solutions for wireless and real-time electrophysiological monitoring. Founded in 2014 and headquartered in Brooklyn, New York, with a research and development facility in University Park, Pennsylvania, Nanowear develops innovative products such as SimplECG, a remote cardiac monitoring undergarment, and SimpleSense, designed for the management of congestive heart failure. These garments collect multi-channel electrocardiogram (ECG), heart rate, and respiratory rate data, transmitting it to a web-based portal accessible by healthcare professionals via a mobile application. The company's proprietary technology serves various markets, including cardiac, neurological, industrial safety, government, sports medicine, and performance diagnostics, providing accurate, continuous, and cost-effective diagnostic data in an unobtrusive manner.

V-Sense Medical is a developer of innovative remote medical monitoring devices designed to enhance patient care in critical medical settings. Utilizing advanced radar technology originally developed by NASA, the company offers a contactless solution for monitoring vital signs, including heart rate and respiratory rate. This approach eliminates the need for traditional monitoring equipment such as wearables, leads, contacts, stickers, or wires, addressing key challenges in medical environments, such as patient safety, comfort, and measurement accuracy. By providing continuous health insights without the burdens of conventional monitoring systems, V-Sense Medical enables healthcare professionals to respond swiftly to patient needs, ultimately improving the efficiency of diagnostic and resuscitative efforts in hospitals and clinics.

TinyKicks is a technology company headquartered in Irvine, California, founded in 2014 by France Helfer. The company specializes in developing a wireless smart sensor system that captures fetal movement using machine learning to promote healthy pregnancy outcomes. Its flagship product, the TinyKicks eMotion fetal activity monitor, is a wearable device that detects the user's baby kicks, distinguishing them from the mother's movements. This continuous monitoring provides real-time data, which is automatically uploaded to the user's smartphone. The system utilizes machine learning algorithms to identify abnormal fetal movement, enabling pregnant women to receive timely notifications about potential complications, thereby reducing costs associated with pregnancy-related issues and enhancing overall pregnancy health tracking.