MedTech Innovator

DiaMonTech AG is a medical technology company based in Berlin, Germany, focused on developing non-invasive diagnostic devices for blood glucose monitoring. Founded in 2015, the company utilizes a proprietary laser-based photo-thermal detection technology to measure glucose levels without the need for blood draws or finger pricking, thereby offering a painless alternative for diabetes management. DiaMonTech's product lineup includes the D-BASE, a device designed for human trials, the D-pocket, a compact personal device for frequent glucose tracking, and the D-BAND, a wearable device that continuously monitors blood sugar levels. Through its innovative solutions, DiaMonTech aims to enhance the quality of life for individuals managing diabetes.

Nanobiofab, founded in 2015 and based in Frederick, Maryland, specializes in the development of wearable, smart healthcare and medical devices utilizing nanotechnology for both humans and pets. The company is known for its product, iNose, which enables users to detect, track, and monitor their body's skin vapor-print. This device wirelessly connects to mobile phones to help individuals assess their fat burning rate and evaluate the effectiveness of their exercise routines. Additionally, it provides insights into the effects of dietary choices over time and tracks metabolic rates. Beyond consumer products, Nanobiofab also offers technology and services aimed at accelerating nanomaterial research and development, including nanoprinting solutions and artificial intelligence sensors for telemedicine and personalized healthcare applications.

FibriCheck is a medically certified mobile application designed for the screening and monitoring of irregular heart rhythms, particularly atrial fibrillation. As a software-only solution, it allows users to measure their cardiac rhythm simply by placing their finger on their smartphone camera, making it accessible anytime and anywhere. The application automatically shares gathered information with medical professionals, facilitating quicker diagnoses and enabling tailored treatment plans. Additionally, FibriCheck employs an artificial intelligence platform that is device-agnostic, leveraging everyday smartphones and wearables to accurately detect and monitor heart rhythm issues. This innovative approach aims to enhance cardiovascular care by providing users with effective tools to manage their heart health, ultimately improving efficiency and reducing costs associated with cardiovascular treatments.

Invicta Medical is a medical technology company focused on developing innovative treatments for sleep apnea and snoring. Founded in 2013 and based in California, the company has created a wearable neurostimulation device that detects and treats disturbed breathing through electrical stimulation. This device aims to overcome the limitations of traditional therapies, which are often expensive, intrusive, and associated with low patient compliance rates. By providing a smart, comfortable, and cost-effective solution, Invicta Medical seeks to enhance the effectiveness of treatment for sleep disorders and improve patient outcomes.

SmartCardia’s platform combines medical wearable technology with Artificial Intelligence to provide unique insights into patient’s health. They have developed SmartNeuralNet, a world-leading machine learning technology that powers their medical wearables. Their mission is to empower the millions of patients with chronic conditions with actionable insights to improve their health.

Proton Intelligence is a Canadian company, founded in 2020 and based in Vancouver, that specializes in biomarker monitoring to assist in managing chronic diseases and improving patient outcomes. The company has developed a wearable continuous potassium monitoring platform aimed at individuals with hyperkalemia, particularly those suffering from chronic kidney disease and other co-morbidities. By providing accurate and real-time potassium measurements through interstitial fluid analysis, Proton Intelligence facilitates critical health monitoring for both clinicians and patients. This technology enables informed decision-making regarding medications, diet, and treatment options, thereby enhancing the management of hyperkalemia and promoting better overall health for affected individuals.

Senseye, Inc. is a company based in Los Angeles, California, focused on developing smart contact lenses that non-invasively gather data from users. Founded in 2015, the company aims to infer human emotions, thoughts, and health states to support various applications in market research, disease diagnosis, and early detection of conditions such as strokes and heart attacks. By utilizing innovative measurements of ocular physiology, Senseye quantifies cognitive abilities, health metrics, and psychological well-being, including vital signs and cognitive load. The platform is designed to enhance clinicians' ability to provide personalized care, allowing them to establish baselines and monitor patient outcomes effectively. As the technology advances, Senseye intends to place greater emphasis on emotional responses and mental health diagnostics, offering new insights into cognitive and health parameters through standard camera equipment.

Neurava is a company focused on developing non-invasive wearable diagnostic devices for patients with epilepsy, particularly those at risk of Sudden Unexpected Death in Epilepsy (SUDEP). The company's innovative device monitors critical biological signals related to epilepsy, providing timely alerts to caregivers and patients. By offering a reliable monitoring solution, Neurava aims to enhance patient autonomy and deliver peace of mind to families, facilitating timely intervention when necessary. The company's work lies at the intersection of medical device manufacturing and health diagnostics, addressing a significant need within the epilepsy patient community.

Flow Neuroscience AB is a healthcare company based in Malmö, Sweden, focused on developing innovative treatment solutions for depression. Established in 2011, the company creates a wearable device that delivers transcranial direct current stimulation (tDCS) to the forehead, targeting the left frontal lobe, an area often associated with reduced activity in individuals suffering from major depressive disorder (MDD). This headset is complemented by a personalized mobile application designed to encourage users to adopt healthier daily routines, such as improved sleep patterns and increased physical activity. By combining brain stimulation with behavioral therapy, Flow Neuroscience aims to provide a medication-free treatment option that is accessible and affordable, challenging the traditional pharmaceutical approaches to depression. The company aspires to make these effective treatments widely available, moving beyond the confines of specialized clinics.

Augment Health focuses on enhancing the management of bladder dysfunction, particularly for the 7 million patients affected by neurological diseases or injuries. The company is developing a noninvasive bladder monitor along with an AI algorithm that allows for home diagnostics, addressing the high rate of inconclusive results seen in clinical settings. By shifting bladder health monitoring out of the clinic, Augment Health's technology aims to prevent complications such as bladder muscle atrophy by notifying patients or caregivers when the catheter is full, thus promoting better bladder health management. This innovation targets a significant market valued at $12.3 billion, providing a practical solution to improve the quality of life for individuals facing bladder dysfunction.

LiveMetric is a medical device company focused on developing non-invasive sensing and deep data analytics solutions aimed at transforming the management of hypertension and cardiovascular diseases. The company has created a wearable, cuff-free device for blood pressure monitoring, which has received FDA clearance and is validated for accuracy against traditional arterial line measurements. This device offers continuous monitoring of vital signs, enabling healthcare providers to deliver AI-augmented care and treatment management. LiveMetric aims to empower patients, payors, and healthcare professionals with accurate, personalized data, facilitating better decision-making and improving the overall quality of care for individuals suffering from chronic cardiovascular conditions. By providing detailed daily activity mapping and real-time feedback, the company seeks to enhance the lives of millions worldwide affected by these health issues.

MindMics is an innovative wearable technology company focused on health monitoring through sound-based platforms integrated into earbuds and hearing aids. By capturing clinically meaningful biometrics in real-time, such as circadian rhythms, breathing rates, body temperature, and heartbeats, MindMics aims to enhance mental performance and overall well-being. The technology allows users to gain insights into their health, facilitating improved focus, satisfaction, and mindfulness. Through this approach, MindMics seeks to provide users with tailored products and experiences that promote mental peace and enhance daily living.

CardiaCare is a developer of a wearable medical device aimed at the non-invasive treatment and monitoring of atrial fibrillation (AFib) in patients at home. The device employs a closed-loop approach and machine learning algorithms to deliver personalized peripheral neuromodulation therapy. This innovative technology mediates a cardiovascular antiarrhythmic response, helping users to alleviate the burden of atrial fibrillation and address precursors such as premature atrial contractions. As a result, CardiaCare’s device offers users the potential for rapid clinical and symptomatic relief.

PyrAmes has developed a paper thin, flexible, ultra low power device for non-invasive monitoring of blood pressure

Flosonics Medical is a medical device company based in Sudbury, Canada, founded in 2017. It specializes in the development of non-invasive sensors aimed at enhancing the management of critically ill patients. The company's flagship product, the FloPatch, is a wearable sensor designed to monitor blood flow in patients' necks following clinical interventions. This innovative device addresses critical clinical needs for healthcare professionals, including physicians, nurses, and paramedics, working in various settings such as ambulances, emergency departments, operating rooms, and intensive care units. By integrating wearable ultrasound technology with connected devices, Flosonics Medical provides portable and user-friendly solutions that facilitate hands-free operation and improve patient care.

toSense, Inc. is a healthcare technology company based in San Diego, California, focused on developing innovative solutions for at-home monitoring of chronic illnesses, particularly for patients with conditions such as congestive heart failure and chronic obstructive pulmonary disease. The company's flagship product, the CoVa Monitoring System, is a wearable sensor designed to monitor various health parameters, including thoracic impedance, heart rate, and respiration rate. This device, worn as a necklace and secured with disposable electrodes, transmits vital signs to gateways that relay the data to a web-based system for clinical review. This technology allows healthcare providers to detect potential issues earlier than traditional monitoring methods, enabling timely intervention. Established in 2008 and formerly known as Perminova, Inc., toSense operates as a subsidiary of Baxter International Inc. and aims to address pressing medical challenges through its hardware and software solutions.

Sepsis Scout is a developer of a wearable patch aimed at predicting the onset of sepsis in high-risk patients in a home care setting. The device utilizes proprietary deep learning technology to enhance the accuracy of sepsis predictions compared to current standards of care. By enabling patients to monitor their health more effectively, Sepsis Scout's solution helps manage chronic illnesses and reduces the need for hospital visits, alleviating the fear and uncertainty associated with serious health conditions.

Bone Health Technologies, Inc. is a health-tech company based in Redwood City, California, focused on developing innovative solutions for individuals with low bone density. The company's flagship product, OsteoBoost, is a wearable medical device that has received FDA clearance and is clinically proven to significantly slow bone density loss and improve bone strength, particularly in postmenopausal women with osteopenia. Utilizing patented precision vibration therapy inspired by NASA-funded research, OsteoBoost provides a non-invasive, non-pharmacological treatment option that mimics the effects of weight-bearing exercise through mechanical stimulation. This device aims to offer a convenient, pain-free solution to the nearly 64 million Americans at risk of osteoporotic fractures, positioning itself as a potential new standard of care in bone health management.

Koya Medical, Inc., founded in 2018 and based in Oakland, California, specializes in developing innovative therapeutic devices aimed at treating cancer-related chronic lymphedema and various venous diseases. The company focuses on creating wearable technology that delivers active compression therapy, which is designed to enhance movement and mobility for patients. Koya Medical's approach offers a personalized alternative to traditional compression methods, utilizing a sensor-based closed-loop system to provide tailored compression patterns. This technology addresses the needs of patients suffering from conditions such as lymphedema, chronic edema, and chronic venous insufficiency, thereby improving their quality of care and overall treatment outcomes.

Spire, Inc. is a San Francisco-based company that specializes in the development of innovative health monitoring devices. Founded in 2013, it focuses on continuous respiration sensing and ambulatory monitoring, providing users with actionable insights into their physical and mental well-being. The company's flagship activity tracker measures key metrics such as inhalation and exhalation times, apneic events, steps, and calories burned. This data is accessible through a mobile application compatible with iPhones, iPods, and iPads, allowing users to gain a deeper understanding of their daily activities and overall state of mind. By leveraging advanced algorithms and sensor technology, Spire aims to enhance health outcomes for both patients and healthcare providers, promoting healthier lifestyles and improved performance through effective tracking of sleep, stress, and physical activity.

Nanowear, Inc. specializes in the development of textile-based nanosensor technology that facilitates wireless and real-time electrophysiological monitoring. Founded in 2014 and headquartered in Brooklyn, New York, the company offers products such as SimplECG, a remote cardiac monitoring undergarment, and SimpleSense, which focuses on the monitoring and management of congestive heart failure. These garments collect multi-channel electrocardiogram (ECG), heart rate, and respiratory rate data, which is transmitted to a web-based portal accessible by healthcare professionals via a mobile application. Nanowear's technology serves various sectors, including cardiac and neurological health, industrial safety, government, sports medicine, and performance diagnostics, providing accurate and continuous diagnostic data in a cost-effective and unobtrusive manner. The company also maintains a research and development facility in University Park, Pennsylvania.

Palmm is a venture capital investment firm that focuses on the development of innovative medical devices. One of its key products provides an at-home treatment for excessive sweating, effectively targeting areas such as the hands. This device utilizes a mild electrical current delivered through wearable garments to deactivate sweat glands, offering a safe and convenient solution to manage hyperhidrosis. By enabling individuals to control sweating, Palmm's technology helps users regain confidence and alleviate the social challenges associated with excessive perspiration.

MiNDERA Corporation specializes in the development of non-invasive molecular testing devices aimed at diagnosing skin cancer and other skin diseases. The company's innovative products include a micro-needle array patch that allows for pain-free and minimally invasive extraction of biomarkers such as RNA, DNA, and proteins from the skin, eliminating the need for traditional skin biopsies. Additionally, MiNDERA is working on a whole transcriptome extraction patch and a skin microbiome extraction patch for various research applications. Founded in 2013, the company is headquartered in Palo Alto, California.

TinyKicks is a technology company based in Irvine, California, founded in 2014 by France Helfer. The company specializes in developing a wireless smart sensor system that captures fetal movement to promote healthy pregnancy outcomes. Its flagship product, the TinyKicks eMotion fetal activity monitor, is a wearable device that detects and distinguishes between the baby's kicks and the mother's movements. This continuous monitoring system automatically uploads data to the user's smartphone, allowing pregnant women to track their baby's activity. By leveraging machine learning algorithms, TinyKicks can identify abnormal fetal movement patterns, alerting users to potential complications and thereby reducing the costs associated with pregnancy-related issues.

Vital's intelligent software for Smart Glasses dramatically improves the accuracy and efficiency of technicians engaged in complex manual tasks such as assembly and maintenance. Its Augmented Reality Dashboard actively supports the technician. Work instructions can be called into view completely hands-free. Each step of a task can be individually checked off, recorded and automatically logged. And see-what-I-see telepresence enables instant support from remote expert colleagues.

Aluna is focused on empowering patients with chronic respiratory conditions, particularly asthma, by providing tools for better understanding and management of their lung health. The company has developed a portable spirometer device that utilizes machine learning and integrates with a mobile app. This technology allows patients to take daily measurements of their asthma, track symptoms, medication use, exercise, and environmental factors. By objectively monitoring asthma severity, the device enables healthcare providers to detect early signs of asthma attacks and create personalized, real-time action plans for their patients. Aluna is committed to enhancing the quality of life for individuals with asthma through innovative medical devices and healthcare solutions.