MedTech Innovator

CytoVeris is a company focused on developing optical-based technologies to assist surgical oncologists in identifying and removing tumor tissue during cancer resection surgeries. Founded in 2018 by Alan Kersey in Farmington, Connecticut, CytoVeris aims to enhance the surgeon's ability to achieve clean margins, thereby improving patient outcomes. The company’s devices facilitate real-time assessment of tissue and generate molecular-specific information by detecting unique signatures created by cancer cells that alter cellular metabolic processes. This includes variations in lipids, proteins, and metabolites, which can be identified using their OncoMap system. By providing oncologists with critical information during surgery, CytoVeris seeks to reduce healthcare costs associated with repeat surgeries.

DiaMonTech AG is a medical technology company based in Berlin, Germany, focused on developing non-invasive diagnostic devices for blood glucose monitoring. Founded in 2015, the company utilizes a proprietary laser-based photo-thermal detection technology to measure glucose levels without the need for blood draws or finger pricking, thereby offering a painless alternative for diabetes management. DiaMonTech's product lineup includes the D-BASE, a device designed for human trials, the D-pocket, a compact personal device for frequent glucose tracking, and the D-BAND, a wearable device that continuously monitors blood sugar levels. Through its innovative solutions, DiaMonTech aims to enhance the quality of life for individuals managing diabetes.

Oxford Endovascular is focused on developing an innovative medical device for the treatment of brain aneurysms. The company's technology employs a laser-cut metal alloy with shape-memory properties, which can be inserted into a patient's brain via a catheter. Once in place, the device expands into a tiny mesh tube, known as a flow diverter, that conforms to the natural shape of the blood vessel. This design effectively diverts blood flow away from the aneurysm, facilitating its healing and reducing the risk of rupture. By utilizing advanced origami engineering, Oxford Endovascular aims to enhance patient outcomes and improve survival rates for those affected by intracranial aneurysms.

Digma Medical is a clinical stage medical device company revolutionizing the treatment of Type-2 Diabetes and other metabolic syndrome disease such as NASH. Founded in 2013 and backed by leading venture capital firms, Digma is dedicated to the development of the DiaGone™ to treat insulin resistance - the underlying mechanism of the disease. The DiaGone™ is an endoscopic, disposable device, that uses state of the art laser technology to treat the duodenum without an implant. The Duodenal Glycemic Control™ procedure is a one-time 30 minute GI procedure, in which the gastroenterologist uses the DiaGone™ to treat the duodenum for restoring the natural ability of the body to control glucose levels, which may provide long term remission from Type-2 Diabetes, NASH, and other metabolic syndrome related disease.

Deneb Medical is a start-up focused on creating a robotic platform intended for various surgical applications, including neurosurgery, cranio-maxillofacial surgery, head and neck surgery, urology, and general surgery. The company's technology centers around a laser-based robotic surgery system that assists surgeons, particularly in spine surgery, by utilizing optical and photonic techniques for tissue ablation. This innovative system enhances surgical precision and efficiency through features such as three-dimensional visualization and augmented reality guidance, ultimately aiming to facilitate minimally invasive procedures and improve patient outcomes.

Innoblative is developing Sira™, a Saline-assisted Intraoperative Radiofrequency Ablation device that uses bipolar current to intraoperatively create a controlled zone of ablation. Sira’s unique design and saline microinfusion system allow it to have unparalleled contact with target tissue and to be powered with existing electrosurgical generators already installed in the operating room. This device represents an exciting new option for intraoperative ablation of soft tissue which surgeons can easily adopt.

Enspectra Health, based in Mountain View, California, specializes in developing advanced imaging systems for medical applications. The company has created the first hand-held multiphoton imager for human use, enabling real-time imaging of live cellular anatomy beneath the skin. Its innovative device combines reflectance confocal and multiphoton laser scanning microscopy to produce multispectral images that reveal details not visible to the naked eye. This technology aids researchers and dermatologists in examining the structure and function of various tissues, including muscle, tendon, cartilage, and skin, thereby enhancing the diagnosis and treatment of skin conditions, particularly skin cancers. Enspectra Health aims to simplify the evaluation process for physicians and improve patient outcomes through its cutting-edge imaging solutions.