Medtronic

FIRE1 and is based in Dublin, Ireland, will focus on developing novel therapeutic devices.

Fortimedix is a global leader in the field of endovascular stents. With full in-house stent development and manufacturing capabilities, they have been a trusted partner for over 15 years. As a leader in stent technology, they invest heavily in research & development which fosters innovation, enables continuous improvement, and fulfils their dedication to operational excellence. At Fortimedix everything they do is inspired by their Mission and Vision. It is of great importance to us that their customers, employees and stakeholders know what they stand for and where they are going.

EOFlow Co., Ltd. is a South Korean company that specializes in drug delivery solutions, focusing primarily on the development and manufacturing of wearable insulin pumps. Its flagship product, EOPatch, is recognized as the world's smallest full-featured disposable insulin pump. This innovative device is designed to be smarter, better-connected, and longer-lasting than its competitors, while also being more cost-effective. EOFlow is also enhancing the EOPatch with software upgrades that will enable closed-loop insulin control, effectively functioning as an automated insulin delivery system. Additionally, the company is working on an all-in-one wearable disposable artificial pancreas solution, which has received Breakthrough Device designation from the FDA, highlighting its potential to significantly impact diabetes management.

FIRE1 and is based in Dublin, Ireland, will focus on developing novel therapeutic devices.

CathWorks Ltd. is a medical technology company that specializes in enhancing percutaneous coronary intervention (PCI) therapy decisions through its advanced computational science platform. Founded in 2013 and headquartered in Kfar-Saba, Israel, with an additional office in the United States, the company has developed the CathWorks FFRangio, a non-invasive device that provides objective, multi-vessel physiologic measurements. This tool transforms coronary angiography from a subjective visual assessment into an objective decision-making framework based on fractional flow reserve (FFR) metrics. By utilizing sophisticated algorithms to process visual information, CathWorks aims to improve the efficiency of cath lab operations and support healthcare providers in making data-driven clinical decisions.

Intersect ENT, Inc. is a medical device company focused on developing innovative therapies for patients with ear, nose, and throat conditions. Founded in 2003 and headquartered in Menlo Park, California, the company specializes in drug delivery products aimed at enhancing treatment outcomes for chronic sinusitis and other related ailments. Its key offerings include the PROPEL and PROPEL mini drug-releasing implants, designed for patients undergoing sinus surgery, as well as the PROPEL Contour implant, which targets frontal and maxillary sinus ostia. Additionally, Intersect ENT provides SINUVA, a steroid-releasing implant intended for use in a physician office setting to address refractory disease. The company was previously known as Sinexus, Inc. before rebranding in 2009.

Scivita Medical is a high-tech enterprise engaged in the field of optical diagnosis and treatment, multidimensional images development, high-performance materials research and precision manufacturing with minimally invasive medical treatment. Scivita Medical's product covers both flexible endoscopy and rigid endoscopy, and has unique advantages in the research and commercialization of all cutting-edge technologies in the field of medical endoscopes. It has ultra-high-definition visualization technology (such as 4K UHD visualization), 3D visualization technology, special light visualization technology (such as fluorescence visualization), ultra-fine endoscopic visualization technology, single-use technology, etc.

Triple Jump Medical is a developer of an insulin pump intended to treat diabetic patients.

Sinovation Medical specializes in the development of advanced medical robotic technology and innovative medical products. The company is dedicated to enhancing precision in healthcare through its surgical robots, which integrate clinical computer vision technology. These robots are primarily utilized in neurosurgery, addressing conditions such as epilepsy, Parkinson's disease, cerebral hemorrhage, and intracranial tumors. By providing reliable medical robotics, Sinovation aims to improve care for patients and support medical professionals in delivering effective treatments.

Medicrea is a specialized spinal implant company committed to delivering innovative technologies for the global healthcare market. With over 18 years of experience, the company offers a comprehensive range of patented products designed to enhance patient outcomes and support healthcare professionals. Medicrea develops personalized analytical services and implant systems aimed at providing long-lasting pain relief for patients undergoing spinal surgery. Its product portfolio includes the UNiD Adaptive Spine Intelligence technology, as well as the PASS Range, Cervical Range, and TH-LUMBAR Range, each tailored to meet specific clinical needs.

Stimgenics is a private company that pioneered a novel spinal cord stimulation waveform known as Differential Target Multiplexed (DTM) Spinal Cord Stimulation.

AV Medical is a medical device company focused on developing catheter-based interventions specifically for dialysis patients who require routine angioplasty procedures. Its primary product, the Chameleon PTA balloon catheter, incorporates innovative Supervision technology that allows for the targeted injection of diagnostic fluids. This feature enables physicians to visualize the status of the balloon—whether inflated or deflated—while maintaining wire position, thereby enhancing procedural efficiency and safety. The Chameleon catheter has undergone clinical testing in various dialysis access procedures, demonstrating its potential to improve outcomes for both patients and healthcare providers.

Saluda Medical is a commercial-stage medical device company focused on developing innovative treatments for chronic neurological conditions, particularly chronic neuropathic pain. The company utilizes a unique closed-loop neuromodulation platform that senses and measures neural responses to stimulation. This technology automatically adjusts the therapy based on real-time neurophysiological feedback, allowing for personalized treatment tailored to each patient's specific needs. By monitoring the patient's neural fingerprint, Saluda Medical’s devices enable the precise delivery of electrical stimulation, ultimately improving the management of chronic back pain and enhancing patient outcomes.

Mazor Robotics Ltd. specializes in developing, producing, and marketing medical devices designed to enhance surgical procedures in orthopedics and neurosurgery. The company focuses on computer-assisted surgery, which allows for the precise and minimally invasive use of surgical instruments, thereby simplifying complex operations. Its primary offerings include the Mazor X and Renaissance surgical guidance systems, which are utilized in spine surgeries for various applications such as spinal fusion, deformity correction, biopsy collection, tumor excision, and cement augmentation. Founded in 2000 and headquartered in Caesarea, Israel, Mazor Robotics primarily generates revenue from the United States market, aiming to improve patient safety and clinical outcomes during surgical procedures.

Nanos Medical specializes in the research, development, manufacturing, and sales of disposable medical devices, primarily focusing on the cardiovascular and ENT (ear, nose, and throat) sectors. The company's product offerings include a range of interventional devices such as sinus balloon catheters, eustachian tube balloons, disposable nasopharyngeal airways, nasolacrimal balloons, and sinus drug-eluting stents. By providing these advanced medical devices, Nanos Medical aims to enhance treatment options for hospitals and improve patient care.

Yosemite Clinic is a full-service clinic providing convenient walk-in medical services in a state-of-the-art environment in Central Pudong. They offer family medicine, internal medicine, surgery, orthopedics (sports medicine), dermatology, medical cosmetology, dentistry, gynecology, pediatrics, ophthalmology, anesthesiology, rehabilitation medicine, medical imaging, laboratory, pharmacy and more. Their onsite facilities and equipment include CT, X-ray, Ultrasound, Laboratory and Operating Rooms. Their doctors come from China and across the world, enabling us to serve you in many languages including, English, Japanese, Malay, Mandarin Chinese and Cantonese.

VisionSense develops innovative visualization solutions designed to enhance minimally invasive surgery (MIS). By utilizing advanced sensor technology and proprietary software, the VisionSense system provides surgeons with stereoscopic sight, delivering depth perception and high-definition 3D images through the smallest access points. Unlike traditional MIS vision solutions that offer only 2D images, VisionSense's technology significantly improves a surgeon's perspective by enabling better tissue understanding and hand-eye coordination. This enhancement allows for the confident use of advanced articulating surgical tools, ultimately facilitating more complex surgical procedures.

FIRE1 and is based in Dublin, Ireland, will focus on developing novel therapeutic devices.

AEGEA Medical, Inc. is a medical technology company based in Menlo Park, California, focused on improving women's healthcare through innovative treatment options. The company has developed a water vapor ablation system, known as Mara, which provides a safe and effective method for endometrial ablation to treat heavy menstrual bleeding, or menorrhagia. This FDA-approved technology allows for a straightforward, office-based procedure that typically takes only minutes to perform. AEGEA is dedicated to enhancing patient outcomes and expanding access to effective therapies, while also supporting physicians in delivering these procedures with confidence and ease. Founded in 2008, AEGEA Medical is committed to pioneering advancements in women’s health.

SetPoint Medical is a clinical-stage bioelectronic medicine company based in Valencia, California, focused on developing implantable neuromodulation devices aimed at treating chronic autoimmune diseases. The company is creating a platform that stimulates the vagus nerve to activate the body's natural inflammatory reflex, leading to a systemic immune-restorative effect. This innovative approach offers an alternative treatment option for conditions such as rheumatoid arthritis and inflammatory bowel disease, with the potential for reduced risks and costs compared to traditional drug therapies. SetPoint Medical, originally known as Innovative Metabolics Inc. until its name change in 2008, aims to provide patients and healthcare providers with effective solutions for managing debilitating inflammatory diseases.

Glooko is a company that develops a remote patient-monitoring platform specifically designed for individuals with diabetes. This platform integrates with various diabetes devices, fitness wearables, and activity trackers to capture and sync health data. It provides comprehensive reports and analytics aimed at promoting behavior change and improving health outcomes. By enhancing communication between patients and healthcare providers, Glooko facilitates better management of diabetes and supports remote monitoring efforts. The platform is accessible on both Android and iOS devices, allowing users to conveniently track their diabetes-related information on their smartphones.

Earlens is a medical technology company focused on improving the hearing experience for individuals with hearing loss. It has created the Earlens Contact Hearing Solution, a unique device that directly stimulates the eardrum using a small lens, replicating the natural hearing process. Unlike conventional hearing aids that amplify sound, the Earlens solution delivers sound directly to the eardrum, providing superior sound quality and a broader bandwidth. This innovative, non-surgical approach allows for automatic adjustments in challenging listening environments while minimizing feedback. The technology received FDA clearance in 2019 for its second generation, marking a significant advancement in hearing solutions aimed at enhancing the quality of life for those with hearing impairment.

Inspire Medical Systems, Inc. is a medical technology company dedicated to developing and commercializing minimally invasive solutions for obstructive sleep apnea (OSA). The company has created the Inspire system, a neurostimulation technology designed to provide safe and effective treatment for moderate to severe OSA. This system employs a proprietary Upper Airway Stimulation (UAS) therapy that utilizes established technologies from cardiac pacing and neurostimulation. Additionally, Inspire is developing a novel closed-loop solution that continuously monitors a patient's breathing and delivers mild hypoglossal nerve stimulation to keep the airway open. Founded in 2007 and headquartered in Golden Valley, Minnesota, Inspire primarily generates its revenue in the United States, with a growing presence in Europe.

MD Start is an incubator and fund dedicated to medical technologies. MD Start creates, develops, and operates medical projects, turning them into new companies with both strategic and hands-on approaches, in order to bring them to investment stage and commercial development.

Mazor Robotics Ltd. specializes in developing, producing, and marketing medical devices designed to enhance surgical procedures in orthopedics and neurosurgery. The company focuses on computer-assisted surgery, which allows for the precise and minimally invasive use of surgical instruments, thereby simplifying complex operations. Its primary offerings include the Mazor X and Renaissance surgical guidance systems, which are utilized in spine surgeries for various applications such as spinal fusion, deformity correction, biopsy collection, tumor excision, and cement augmentation. Founded in 2000 and headquartered in Caesarea, Israel, Mazor Robotics primarily generates revenue from the United States market, aiming to improve patient safety and clinical outcomes during surgical procedures.

HeartWare International, Inc. specializes in the development and manufacturing of small implantable heart pumps, also known as ventricular assist devices, aimed at treating advanced heart failure. The company offers the HeartWare Ventricular Assist System, which comprises a left ventricular assist device, patient accessories, and surgical tools designed to provide critical circulatory support for patients in the advanced stages of heart failure. Additionally, HeartWare is working on the Miniaturized Ventricular Assist Device, intended for chronic heart failure patients. The company markets its products through clinical studies in the United States and directly to cardiac centers and hospitals worldwide. Headquartered in Framingham, Massachusetts, HeartWare is committed to improving the quality of life for patients suffering from severe heart conditions.

Earlens is a medical technology company focused on improving the hearing experience for individuals with hearing loss. It has created the Earlens Contact Hearing Solution, a unique device that directly stimulates the eardrum using a small lens, replicating the natural hearing process. Unlike conventional hearing aids that amplify sound, the Earlens solution delivers sound directly to the eardrum, providing superior sound quality and a broader bandwidth. This innovative, non-surgical approach allows for automatic adjustments in challenging listening environments while minimizing feedback. The technology received FDA clearance in 2019 for its second generation, marking a significant advancement in hearing solutions aimed at enhancing the quality of life for those with hearing impairment.

Responsive Orthopedics is a start-up focused on sales of low-cost hip and knee replacements. Its products are intended exclusively for healthcare providers participating in federal programs to reduce the costs of hip and knee procedures. The company was founded in 2013 and is based in Minneapolis. In June 2016, Responsive Orthopedics was acquired by [Medtronic](/organization/medtronic).

Bellco is an Italian company recognized as a pioneer in the field of haemodialysis. It specializes in the manufacture and distribution of medical devices for renal care, including dialyzers, fluids, machines, and hematic lines specifically designed for treating kidney diseases. The company is committed to addressing the needs of both patients and healthcare professionals through continuous innovation and research. In addition to its core focus on haemodialysis, Bellco also develops products for extra-corporeal blood filtration, showcasing its dedication to advancing therapies in nephrology, intensive care, and cardiology.

Aircraft Medical Limited is a developer and producer of high-quality medical devices focused on anesthesia and critical care. The company specializes in portable solutions, notably the McGRATH video laryngoscope, which enhances the safety and efficiency of airway management. Its products are designed to minimize patient trauma, reduce cross-contamination, and facilitate better communication during clinical training. Aircraft Medical markets its offerings through distribution partners across multiple regions, including North America and Europe. Founded in 2001 and based in Edinburgh, United Kingdom, the company was previously known as Smartscope MD Ltd. and became a subsidiary of Medtronic plc in 2015.

SetPoint Medical is a clinical-stage bioelectronic medicine company based in Valencia, California, focused on developing implantable neuromodulation devices aimed at treating chronic autoimmune diseases. The company is creating a platform that stimulates the vagus nerve to activate the body's natural inflammatory reflex, leading to a systemic immune-restorative effect. This innovative approach offers an alternative treatment option for conditions such as rheumatoid arthritis and inflammatory bowel disease, with the potential for reduced risks and costs compared to traditional drug therapies. SetPoint Medical, originally known as Innovative Metabolics Inc. until its name change in 2008, aims to provide patients and healthcare providers with effective solutions for managing debilitating inflammatory diseases.

Twelve manufactures medical devices. It was formerly known as Foundry Newco XII, Inc. The company was incorporated in 2009 and is based in Menlo Park, California.

AEGEA Medical, Inc. is a medical technology company based in Menlo Park, California, focused on improving women's healthcare through innovative treatment options. The company has developed a water vapor ablation system, known as Mara, which provides a safe and effective method for endometrial ablation to treat heavy menstrual bleeding, or menorrhagia. This FDA-approved technology allows for a straightforward, office-based procedure that typically takes only minutes to perform. AEGEA is dedicated to enhancing patient outcomes and expanding access to effective therapies, while also supporting physicians in delivering these procedures with confidence and ease. Founded in 2008, AEGEA Medical is committed to pioneering advancements in women’s health.

Ortho Kinematics is a spine diagnostics company, provides spine motion analysis and diagnostic services. The company provides information to spine clinicians to assist them in diagnosing and treating back and neck pain. Its solution includes KineGraph Vertebral Motion Analyzer, an automated functional diagnostic test for the spine that uses fluoroscopy to capture the spine in motion, producing patient-specific graphs of the kinematics for each vertebral level. The company was founded in 2006 and is based in Austin, Texas.

DreaMed Diabetes, Ltd. is a medical device and software-as-a-service company focused on diabetes treatment and management. Founded in 2014 and based in Israel, the company is known for its innovative solutions, including Glucositter, a closed-loop insulin delivery system that monitors glucose levels in real-time and adjusts insulin delivery accordingly. DreaMed Diabetes has made significant advancements in decision support tools for diabetes management and was the first company to receive FDA clearance for a decision support system that utilizes data from continuous glucose monitors and insulin pumps. Its Advisor Pro software, developed by diabetes professionals, leverages artificial intelligence to enable healthcare providers to quickly analyze patient data and determine optimal treatment plans. This system aims to improve patient outcomes by facilitating frequent titration changes and enhancing online monitoring, ultimately helping to lower A1C levels and reduce the risk of complications. DreaMed Diabetes emphasizes patient-centered care, ensuring that all individuals receive high-quality treatment regardless of their circumstances.

Sophono, Inc. is a medical device manufacturer based in Boulder, Colorado, specializing in implantable magnetic bone conduction hearing devices. Founded in 2009, the company focuses on providing solutions for individuals with conductive hearing loss, mixed hearing loss, and single-sided deafness. Its flagship product, the Alpha 2 MPO, offers an abutment-free design that allows for under-the-skin implantation, enhancing user comfort and convenience. Sophono's devices are designed for patients experiencing severe to profound hearing impairment, and they are distributed through clinics. As of 2015, Sophono operates as a subsidiary of Medtronic plc.

Glooko is a company that develops a remote patient-monitoring platform specifically designed for individuals with diabetes. This platform integrates with various diabetes devices, fitness wearables, and activity trackers to capture and sync health data. It provides comprehensive reports and analytics aimed at promoting behavior change and improving health outcomes. By enhancing communication between patients and healthcare providers, Glooko facilitates better management of diabetes and supports remote monitoring efforts. The platform is accessible on both Android and iOS devices, allowing users to conveniently track their diabetes-related information on their smartphones.

Founded by Dr. Eugenio Cremascoli, the main business of NGC Medical Focuses are: Project planning, manufacturing and marketing of medical and surgical devices Import and distribution in national territory of medical devices, medical data management systems, medical communications database for remote access and medical equipment Design and turnkey implementation of Surgery Units, Intensive Care, Hemodynamics, Electrophysiology and Intervention Radiology Laboratories In-service management of Surgical Suites, Intensive Care, Hemodynamics, Electrophysiology and Intervention Radiology Laboratories Design and implementation of Information Management Software packages unifying the administrative and clinical departments within at single interface

Sapiens Steering Brain Stimulation GmbH is an emerging medical device company whose mission is to deliver superior solutions for deep brain stimulation (DBS) therapy. Sapiens' ambition is to provide a unique, high-resolution, and MRI- compatible DBS system that will improve patient comfort and therapeutic outcome, initially for patients with Parkinson's disease. Sapiens, with offices in Eindhoven, the Netherlands and Munich, Germany, is founded in 2011 as a spin-out of Royal Philips Electronics. Its steering brain stimulation (SBS) system and image-guided programming are based upon patented technologies.

Visualase, Inc. was founded in 2005 as a spin-off from BioTex, Inc., the original developer and current manufacturer of the Visualase technology. Visualase, Inc. is currently a privately held company located in Houston, Texas.

Inspire Medical Systems, Inc. is a medical technology company dedicated to developing and commercializing minimally invasive solutions for obstructive sleep apnea (OSA). The company has created the Inspire system, a neurostimulation technology designed to provide safe and effective treatment for moderate to severe OSA. This system employs a proprietary Upper Airway Stimulation (UAS) therapy that utilizes established technologies from cardiac pacing and neurostimulation. Additionally, Inspire is developing a novel closed-loop solution that continuously monitors a patient's breathing and delivers mild hypoglossal nerve stimulation to keep the airway open. Founded in 2007 and headquartered in Golden Valley, Minnesota, Inspire primarily generates its revenue in the United States, with a growing presence in Europe.

TyRx specializes in the design, development, and commercialization of resorbable polymeric biomaterials, focusing on drug-device combination products. The company offers PIVIT CRM, a mesh-based pouch designed to protect against microbial colonization of surgical implants such as generators and defibrillators during and immediately after surgery. Additionally, TyRx provides AIGISRx Flat, an antibacterial solution aimed at preventing infections linked to implanted pacemakers and defibrillators. Founded in 1997 and headquartered in Monmouth Junction, New Jersey, TyRx is committed to advancing medical technology through innovative products that enhance patient safety.

Cardiocom is the leader in telemedicine solutions for daily remote patient monitoring and disease management. Cardiocom provides health professionals with home telemonitoring equipment and telehealth services to identify symptomatic patients and intervene early to prevent unnecessary hospitalizations. Cardiocom addresses CHF, COPD, Asthma, Diabetes, Hypertension and Obesity. We offer a variety of health monitoring product and service options to meet your organization's specific needs. Cardiocom can provide in-house case managers with the Cardiocom OMNIVISOR PRO® Patient Management System, TELESCALE® for CHF management and COMMANDER for complex patients with multiple diseases. Cardiocom's proven, proactive solutions for daily patient disease management result in improved quality of life and direct savings to the health management group.

Intersect ENT, Inc. is a medical device company focused on developing innovative therapies for patients with ear, nose, and throat conditions. Founded in 2003 and headquartered in Menlo Park, California, the company specializes in drug delivery products aimed at enhancing treatment outcomes for chronic sinusitis and other related ailments. Its key offerings include the PROPEL and PROPEL mini drug-releasing implants, designed for patients undergoing sinus surgery, as well as the PROPEL Contour implant, which targets frontal and maxillary sinus ostia. Additionally, Intersect ENT provides SINUVA, a steroid-releasing implant intended for use in a physician office setting to address refractory disease. The company was previously known as Sinexus, Inc. before rebranding in 2009.

Mitralign is a privately held company based in a suburb of Boston, Massachusetts, focused on developing a catheter-based technology for the treatment of functional mitral regurgitation. The company has created an innovative system that mimics surgical annuloplasty by delivering surgical implants directly into the mitral annulus via a catheter. This process involves cinching the implants together to decrease the size of the mitral valve annulus and the valve opening. Mitralign's technology aims to provide a less invasive option for managing this life-threatening cardiac condition, enabling healthcare providers to effectively treat symptomatic functional mitral regurgitation through tissue-plication. The company is supported by prominent venture capitalists and has attracted investments from major cardiovascular device firms.

Inspire Medical Systems, Inc. is a medical technology company dedicated to developing and commercializing minimally invasive solutions for obstructive sleep apnea (OSA). The company has created the Inspire system, a neurostimulation technology designed to provide safe and effective treatment for moderate to severe OSA. This system employs a proprietary Upper Airway Stimulation (UAS) therapy that utilizes established technologies from cardiac pacing and neurostimulation. Additionally, Inspire is developing a novel closed-loop solution that continuously monitors a patient's breathing and delivers mild hypoglossal nerve stimulation to keep the airway open. Founded in 2007 and headquartered in Golden Valley, Minnesota, Inspire primarily generates its revenue in the United States, with a growing presence in Europe.

Visualase, Inc. was founded in 2005 as a spin-off from BioTex, Inc., the original developer and current manufacturer of the Visualase technology. Visualase, Inc. is currently a privately held company located in Houston, Texas.

AcuFocus, Inc. is an ophthalmic medical device company based in Irvine, California, specializing in small aperture technologies aimed at enhancing near vision. The company offers the KAMRA inlay, designed to restore near vision for presbyopic patients while preserving distance vision. Additionally, AcuFocus develops the IC-8 IOL, a small aperture lens that facilitates a range of vision for patients with cataracts. The AcuTarget HD is another key product, serving as a diagnostic and surgical planning instrument for various vision correction procedures, including LASIK and cataract surgeries. AcuFocus markets its products through distribution partners across the Americas, Asia-Pacific, Europe, and the Middle East, addressing the needs of both physicians and patients in the vision care sector. Founded in 2001, AcuFocus continues to focus on innovative solutions for vision-related challenges.

Spinal Modulation, Inc., based in Menlo Park, California, specializes in the research and development of medical devices aimed at treating chronic pain. With a significant portion of the adult population affected by severe chronic pain and limited treatment options available, the company addresses this critical healthcare challenge through its Axium Neurostimulator System. This next-generation intraspinal neuromodulation therapy specifically targets the dorsal root ganglion (DRG) to deliver electrical pulses that disrupt pain signals before they reach the brain. The system has demonstrated effectiveness in managing chronic intractable leg pain and other complex pain areas, such as the back and foot, providing a tailored approach for pain relief. By allowing adjustments to focus on either broad or specific pain areas, Spinal Modulation's technology aims to enhance patient comfort and reduce the adverse effects commonly associated with traditional spinal cord stimulators.

PhysioSonics, a development-stage device company based in Washington, focuses on ultrasound imaging to monitor blood flow in the brain.

Osteotech is focused on the development, manufacturing, and marketing of biologic, biomaterial, and device systems for musculoskeletal surgeries. It facilitates spinal, trauma, and total joint revision procedures. Osteotech was acquired by Medtronic in November 2010. It was founded in 1986 in Eatontown, New Jersey.

Intersect ENT, Inc. is a medical device company focused on developing innovative therapies for patients with ear, nose, and throat conditions. Founded in 2003 and headquartered in Menlo Park, California, the company specializes in drug delivery products aimed at enhancing treatment outcomes for chronic sinusitis and other related ailments. Its key offerings include the PROPEL and PROPEL mini drug-releasing implants, designed for patients undergoing sinus surgery, as well as the PROPEL Contour implant, which targets frontal and maxillary sinus ostia. Additionally, Intersect ENT provides SINUVA, a steroid-releasing implant intended for use in a physician office setting to address refractory disease. The company was previously known as Sinexus, Inc. before rebranding in 2009.

Axon Systems is the designer and manufacturer of various NIM Eclipse nerve monitoring systems, which have been marketed and sold in the United States by the Spinal and Biologics business at Medtronic for the past three years. These devices are used in surgery to enhance patient safety by protecting delicate nerves during implant procedures. Axon Systems has introduced an impressive number of "firsts" in the field of neuromonitoring, including: 16 and 32 channel simultaneous multimodality systems, integrated transcranial MEP, microscope and vital signs views, and integrated TCD and pulse oximetery.

CardioMEMS is a medical device company focused on the development and commercialization of proprietary wireless sensing and communication technology aimed at enhancing the management of severe chronic cardiovascular diseases, including heart failure, hypertension, and aneurysms. The company's innovative platform features miniature wireless sensors that can be implanted using minimally invasive techniques. These sensors transmit vital data, such as cardiac output, blood pressure, and heart rate, which are essential for effective patient management. By providing continuous monitoring, CardioMEMS' technology aims to improve patient outcomes and facilitate timely medical interventions.

Atreo Medical is focused on creating innovative medical tools designed to improve resuscitation efforts. The company's flagship product, the CPRGlove, serves as a guide for users to effectively perform cardiopulmonary resuscitation (CPR), enhancing the quality of this critical life-saving procedure both in hospital settings and in emergencies outside of medical facilities. By making resuscitation techniques more accessible, Atreo Medical aims to empower individuals to provide effective first aid in urgent situations.

Microchips Biotech, Inc. is dedicated to improving the lives of patients by revolutionizing drug delivery. Our proprietary microchip-based implant can store and release precise doses of drugs over months and years. The implant, which is placed under the skin by a trained physician during a simple office procedure using local anesthesia, can be wirelessly activated or deactivated by a physician or patient, without requiring removal. In addition, physicians can wirelessly modify the frequency or dose of the drug to meet the individual needs of each patient.

GI Dynamics, Inc., a medical device company, develops therapies for the treatment of type 2 diabetes and related metabolic diseases in the United States. Its products also include EndoBarrier, a non-surgical therapy to treat type 2 diabetes and obesity. The company was founded in 2003 and is based in Lexington, Massachusetts.

CardioMEMS is a medical device company focused on the development and commercialization of proprietary wireless sensing and communication technology aimed at enhancing the management of severe chronic cardiovascular diseases, including heart failure, hypertension, and aneurysms. The company's innovative platform features miniature wireless sensors that can be implanted using minimally invasive techniques. These sensors transmit vital data, such as cardiac output, blood pressure, and heart rate, which are essential for effective patient management. By providing continuous monitoring, CardioMEMS' technology aims to improve patient outcomes and facilitate timely medical interventions.

Inspire Medical Systems, Inc. is a medical technology company dedicated to developing and commercializing minimally invasive solutions for obstructive sleep apnea (OSA). The company has created the Inspire system, a neurostimulation technology designed to provide safe and effective treatment for moderate to severe OSA. This system employs a proprietary Upper Airway Stimulation (UAS) therapy that utilizes established technologies from cardiac pacing and neurostimulation. Additionally, Inspire is developing a novel closed-loop solution that continuously monitors a patient's breathing and delivers mild hypoglossal nerve stimulation to keep the airway open. Founded in 2007 and headquartered in Golden Valley, Minnesota, Inspire primarily generates its revenue in the United States, with a growing presence in Europe.

PreciSense A/S, a Denmark-based development company focused on continuous glucose monitoring (CGM) technology.

CryoCath Technologies develops, manufactures, and markets cryoablation catheter systems for the treatment of cardiac arrhythmias, tumours and other obstructions in the body. These systems comprise flexible, steerable catheters that are supported by electromechanical consoles that deliver and recover refrigerants from the catheters that are placed in the body through minimally-invasive means. The key offerings of CryoCath include electrophysiology products such as Achieve Mapping Catheter, Arctic Front and FlexCath, The CryoConsole, Freezor, Freezor MAX, and Freezor Xtra. The company offers its products through distributors in the regions of Europe, North America, Middle East and the Russian Federation. Currently, CryoCath Technologies operates as a subsidiary of Medtronic, Inc.

Established in 1999, Restore Medical is a privately-held company focused on becoming the primary resource for physicians specializing in sleep and breathing disorders. Restore Medical has developed and markets proprietary implant technology which addresses such disorders as snoring and sleep apnea. The company's first product based on this technology, the patented Pillar™ System, received market clearance from the Food and Drug Administration in late 2002 and is currently available throughout the United States. Restore Medical also distributes other related high-quality products to the Ear, Nose and Throat physicians through our dedicated sales team. Located in St. Paul, Minnesota, Restore Medical manufactures the Pillar™ System in its onsite state-of-the-art Class 100,000 Clean Room. The company is ISO 9001 certified and utilizes an intranet-based quality and product development system. Restore currently employs a team of approximately 55 professionals.

NDI Medical, established in 2002 and based in Cleveland, Ohio, operates as a medical device incubator specializing in neurostimulation technologies. The company is dedicated to developing high-growth enterprises that aim to address significant unmet health needs. NDI Medical's team comprises experienced entrepreneurs, scientists, and physician advisors, along with experts in clinical and regulatory affairs, product development, quality assurance, and finance. By focusing on innovative neuro-device technologies, NDI Medical seeks to advance the field of medical devices and improve therapeutic outcomes for patients.

Arbor Surgical Technologies, Inc. located in Irvine and Portola Valley, CA (USA), is a privately held cardiovascular medical device company focused on the heart valve replacement market. Founded in 2002 by Dr. Thomas J. Fogarty and noted heart valve designer, Ernie Lane, Arbor is developing multiple technologies that have the potential to deliver significant clinical benefit to patients worldwide. Arbor intends to develop and commercialize its core technologies in varying combinations, giving the company the opportunity to create a portfolio of product offerings. Currently in clinical trials, Arbor is developing a tissue heart valve family of products designed for improved performance over existing valves and compatible implantation tools that simplify and speed valve replacement surgery.

Mitralign is a privately held company based in a suburb of Boston, Massachusetts, focused on developing a catheter-based technology for the treatment of functional mitral regurgitation. The company has created an innovative system that mimics surgical annuloplasty by delivering surgical implants directly into the mitral annulus via a catheter. This process involves cinching the implants together to decrease the size of the mitral valve annulus and the valve opening. Mitralign's technology aims to provide a less invasive option for managing this life-threatening cardiac condition, enabling healthcare providers to effectively treat symptomatic functional mitral regurgitation through tissue-plication. The company is supported by prominent venture capitalists and has attracted investments from major cardiovascular device firms.

REVA Medical, Inc. is a medical device company specializing in the development and commercialization of polymer-based bioresorbable products for vascular applications. The company focuses on innovative solutions for coronary artery disease and peripheral artery disease, offering its lead products: the Fantom Encore, a bioresorbable vascular scaffold for coronary artery treatment, and the MOTIV scaffold for below-the-knee applications. These products are designed to support the artery during the healing process and subsequently dissolve, restoring natural artery function. REVA Medical markets its Fantom Encore product in several European countries, including Germany, Austria, and Italy. Founded in 1998 and headquartered in San Diego, California, REVA Medical aims to improve patient health through the use of advanced biomaterials in implantable medical devices.

Setagon, Inc. develops drug delivery technologies for the intravascular treatment of cardiovascular, peripheral vascular, and neurovascular diseases. The company offers drug delivery systems for coated stents market.

Kyphon is a medical device company based in Switzerland that specializes in developing minimally invasive technologies for the treatment of spinal conditions. As a subsidiary of Medtronic, Inc., Kyphon focuses on producing surgical systems, instruments, and materials designed to restore spinal anatomy and function. The company's primary offerings include devices used in balloon kyphoplasty, a procedure aimed at treating spinal compression fractures, often resulting from osteoporosis or cancer. Through its innovative approaches, Kyphon aims to enhance patient outcomes by providing effective solutions for diagnosing and addressing low back pain.

InnerPulse, Inc. develops technology, devices, software protocols, and procedures to transform the treatment of cardiac arrhythmias. It offers invasive treatment that enables physicians to implant the life-saving Percutaneous Implantable Cardioverter Defibrillator within the patient's vascular system. InnerPulse, Inc. was formerly known as Interventional Rhythm Management, Inc.

CardioMEMS is a medical device company focused on the development and commercialization of proprietary wireless sensing and communication technology aimed at enhancing the management of severe chronic cardiovascular diseases, including heart failure, hypertension, and aneurysms. The company's innovative platform features miniature wireless sensors that can be implanted using minimally invasive techniques. These sensors transmit vital data, such as cardiac output, blood pressure, and heart rate, which are essential for effective patient management. By providing continuous monitoring, CardioMEMS' technology aims to improve patient outcomes and facilitate timely medical interventions.

Odin Medical Technologies develops, manufactures and commercializes Intraoperative MRI systems designed for use by the neurosurgeon in standard ORs. The compact, open PoleStar N-10* is a real-time imaging and navigation system utilized during all stages of brain surgery. The unit offers the neurosurgeon the differentiation capabilities of MRI without restricting the freedom of the surgical team to access the patient. The Company�s mission is to improve neurosurgical interventions with minimally invasive procedures. *PoleStar N-10 is FDA cleared for intraoperative MR imaging in a conventional O.R.

Transneuronix, Inc. is a privately held medical device company focused on the treatment of obesity by stimulation of the stomach with an implantable pacemaker-like device.

Vascular Architects, Inc. specializes in designing, developing, manufacturing, and marketing medical devices aimed at treating vascular stenoses, occlusions, and non-vascular obstructions, with a particular focus on peripheral vascular disease. Founded in October 1997 by Dr. Thomas J. Fogarty, a distinguished surgeon and inventor, the company has established itself within the medical device industry by creating innovative surgical products for various markets, including cardiovascular and urology. Vascular Architects develops intraoperative vascular instruments such as Doppler probes and medical oxygen sensors, which are utilized across multiple surgical specialties. The company benefits from the expertise of a highly experienced management team and has engaged key opinion leaders from the interventional and vascular surgery communities to contribute to its Scientific Advisory Board.

As of January 27, 2004, Percutaneous Valve Technologies was acquired by Edwards Lifesciences Corp. The company develops medical devices for delivering heart valves to treat late-stage aortic stenosis. Percutaneous Valve Technologies, Inc. was founded in 1999 and is based in Fort Lee, New Jersey.

Transvascular develops products for the treatment of coronary and peripheral vascular disease and congestive heart failure.

Spinal Dynamics develops neuro-surgical devices for the replacement of spinal disks. The company's Bryan Cervical Disc System is an implanted prosthesis designed to replace and mimic the flexibility and shock-absorbing characteristics of natural intervertebral discs. It features a shock-absorbing elastomer that is intended to cushion the vertebrae and allow movement of the head and neck and is designed to replace the disc that is removed from the patient in cervical spine surgery.

Odin Medical Technologies develops, manufactures and commercializes Intraoperative MRI systems designed for use by the neurosurgeon in standard ORs. The compact, open PoleStar N-10* is a real-time imaging and navigation system utilized during all stages of brain surgery. The unit offers the neurosurgeon the differentiation capabilities of MRI without restricting the freedom of the surgical team to access the patient. The Company�s mission is to improve neurosurgical interventions with minimally invasive procedures. *PoleStar N-10 is FDA cleared for intraoperative MR imaging in a conventional O.R.

Paceart Optima System organizes and archives data for cardiac devices across multiple manufacturers and serves.

MiniMed, is currently developing an implantable insulin pump and a fully implanted long-term glucose sensor. In combination, these implantable products would create a closed-loop, ``artificial pancreas,'' allowing for more efficient regulation of blood glucose levels and a decrease in the frequency and severity of diabetic complications.

Spinal Dynamics develops neuro-surgical devices for the replacement of spinal disks. The company's Bryan Cervical Disc System is an implanted prosthesis designed to replace and mimic the flexibility and shock-absorbing characteristics of natural intervertebral discs. It features a shock-absorbing elastomer that is intended to cushion the vertebrae and allow movement of the head and neck and is designed to replace the disc that is removed from the patient in cervical spine surgery.

PercuSurge is a developer of emboli-protection devices for the prevention of stoke and heart attack.

Xomed Surgical Products makes image-guided products to treat chronic sinusitis, which the company said affects more than 35 million Americans each year, as well as products to treat middle-ear infections, tonsil infections and sleep apnea. It has manufacturing facilities in Florida, Connecticut and France.

Physio-Control, Inc. specializes in emergency medical response products and services, with a strong reputation for its LIFEPAK defibrillators, which are widely recognized by first responders and healthcare professionals. The company focuses on developing advanced technologies and designing high-quality devices that meet the needs of both clinical care providers and everyday citizens. In addition to defibrillators, Physio-Control offers chest compression systems and cloud-based data management solutions, establishing itself as a leader in the industry. Its commitment to customer-driven product development has set a benchmark for quality and reliability in emergency medical equipment.