Medtronic

Rosenbot provides medical robot technology and uses technological innovation to promote the reform of medical models. It is committed to creating a new generation of orthopedic surgery robot systems with intelligent fracture reduction functions, it is the first in the world to realize advanced technologies such as intraoperative real-time 3D navigation, assisted fracture reduction operation, automatic operation planning, etc. The intelligent surgical operation of the whole operation process meets the urgent needs of clinical treatment.

FIRE1 is an Irish-based company specializing in the development of innovative therapeutic devices. Its flagship product is a remote monitoring system designed to enhance heart failure patients' lives by providing real-time data to healthcare providers, facilitating early detection and proactive interventions.

Fortimedix B.V., founded in 1999 and based in Nuth, the Netherlands, specializes in the development and manufacturing of endovascular, coronary, and peripheral stents. As a global leader in stent technology, the company has established a strong presence in the medical device industry, focusing on innovation and continuous improvement. With full in-house capabilities for stent development and production, Fortimedix is dedicated to operational excellence. The company prioritizes research and development to advance its technology and meet the evolving needs of its customers and stakeholders.

Avation Medical, Inc. is a company focused on developing a non-invasive closed-loop neuromodulation system aimed at treating overactive bladder in a home setting. Incorporated in 2016 and based in Columbus, Ohio, Avation Medical is at the forefront of innovation in wearable nerve stimulation systems. The company emphasizes empowering patients to manage their therapies, facilitating a more personalized approach to care. By leveraging advanced technologies, Avation Medical seeks to transform the neuromodulation market, enhancing the quality of care for individuals with chronic conditions through patient-centric solutions.

EOFlow Co., Ltd. is a South Korean company specializing in drug delivery solutions, particularly in the development of wearable insulin pumps. Its flagship product, EOPatch, is recognized as the world's smallest full-featured disposable insulin pump, designed to be smarter, better-connected, and longer-lasting than competing devices, all while being more cost-effective. The company plans to enhance EOPatch with a software upgrade that will enable closed-loop insulin control, effectively functioning as an automated insulin delivery system or "artificial pancreas." Additionally, EOFlow is working on an all-in-one wearable disposable artificial pancreas solution, which has received Breakthrough Device designation from the FDA, highlighting its potential impact on diabetes management.

FIRE1 is an Irish-based company specializing in the development of innovative therapeutic devices. Its flagship product is a remote monitoring system designed to enhance heart failure patients' lives by providing real-time data to healthcare providers, facilitating early detection and proactive interventions.

CathWorks is a medical technology company that applies computational science platforms to enhance percutaneous coronary intervention (PCI) therapy decisions. It offers CathWorks FFRangio, a non-invasive device delivering objective multi-vessel physiologic measurements to optimize and confirm intra-procedural PCI therapies.

CathWorks is a medical technology company that applies computational science platforms to enhance percutaneous coronary intervention (PCI) therapy decisions. It offers CathWorks FFRangio, a non-invasive device delivering objective multi-vessel physiologic measurements to optimize and confirm intra-procedural PCI therapies.

Beijing Surgerii Technology Co., Ltd. specializes in the research, development, production, and sale of minimally invasive surgical robot systems in China. Founded in 2014 and based in Beijing, the company focuses on innovative technologies, particularly the next generation of flexible continuum robotic arms. Surgerii Technology aims to transform clinical practices through its single-hole and porous laparoscopic robot systems, enhancing the standard of care in minimally invasive surgeries. With a commitment to independent research and development, the company leverages its expertise in system design and integration to advance the medical equipment industry in China.

Titan Medical Inc. is a research and development stage company based in Toronto, Canada, specializing in the design and development of robotic surgical technologies for minimally invasive surgery (MIS). The company is advancing its flagship product, the SPORT Surgical System, which features a surgeon-controlled patient cart equipped with a 3D high-definition vision system and multi-articulating instruments. This system enables surgeons to perform a variety of surgical procedures, including gynecologic, urologic, colorectal, and abdominal surgeries, through a single port. Additionally, Titan Medical is also developing the Enos robotic single-access surgical system, further enhancing its focus on innovative solutions in the field of robotic-assisted surgery.

Affera, Inc. is a medical technology company founded in 2013 and based in Watertown, Massachusetts. It focuses on developing innovative solutions for the treatment of cardiac arrhythmia, a common condition that affects millions of patients globally. The company is engaged in the design and development of a novel medical system aimed at addressing the unmet needs in the treatment of heart rhythm disorders. Through its advancements, Affera seeks to enhance the capabilities of healthcare institutions in managing and treating these conditions effectively.

Beijing Surgerii Technology Co., Ltd. specializes in the research, development, production, and sale of minimally invasive surgical robot systems in China. Founded in 2014 and based in Beijing, the company focuses on innovative technologies, particularly the next generation of flexible continuum robotic arms. Surgerii Technology aims to transform clinical practices through its single-hole and porous laparoscopic robot systems, enhancing the standard of care in minimally invasive surgeries. With a commitment to independent research and development, the company leverages its expertise in system design and integration to advance the medical equipment industry in China.

Founded in 2003, Intersect ENT is a medical device company based in Menlo Park, California. It specializes in developing innovative therapies for Ear, Nose, and Throat surgeons to enhance patient care, focusing on treatments for chronic rhinosinusitis.

Scivita Medical is a high-tech enterprise specializing in optical diagnosis and treatment, as well as the development of multidimensional imaging technologies and high-performance materials. The company focuses on precision manufacturing for minimally invasive medical procedures and is recognized for its advancements in endoscopy technology. Scivita Medical offers a range of products that include flexible and rigid endoscopes, featuring innovations such as ultra-high-definition visualization, 3D imaging, and specialized light visualization techniques, including fluorescence. Its portfolio encompasses various medical devices, including 4K medical endoscope camera systems, integrated endoscope systems, and single-use electronic instruments like hysteroscopes, bladder pyeloscopes, and bronchoscopes. These products are designed to provide healthcare professionals with efficient tools for diagnosis and treatment, enhancing the capabilities of modern endoscopic procedures.

Marblehead Medical specializes in the development of a novel medical device designed to enhance the effectiveness of mechanical thrombectomy procedures in treating ischemic strokes. Their innovative device aims to improve support for distal access devices, boost suction efficiency, minimize the risk of embolic events, and accommodate modern catheters, ultimately offering stroke patients improved treatment options.

BrainsGate is a medical device company that develops therapies for central nervous system diseases, focusing on acute ischemic stroke. Its platform uses electrical stimulation of the spheno‑palatine ganglion (SPG) via a miniature electrode implanted in the roof of the mouth. The procedure is minimally invasive, performed at bedside under local anesthesia, and is designed to increase cerebral blood flow. The company has completed several clinical studies, including the ImPACT‑1 pilot, a 300‑patient randomized controlled trial, and is currently conducting the ImpACT‑24b pivotal study. Founded in 2000, BrainsGate is headquartered in Caesarea, Israel.

Ai Biomed is a Santa Barbara-based company that specializes in the development of advanced parathyroid detection systems. Its technology enables the real-time identification of parathyroid tissue during various surgical procedures, including thyroidectomy and parathyroidectomy, as well as radical neck dissection. This innovative approach enhances surgical accuracy and patient safety by facilitating the preservation of critical parathyroid glands during operations.

Triple Jump Medical is a developer of an insulin pump intended to treat diabetic patients.

BioProtect specializes in developing and commercializing biodegradable balloon spacers to protect normal tissue during cancer radiation therapy. Its flagship product, ProSpace, has demonstrated superior efficacy and safety in protecting the rectum during prostate cancer radiotherapy. BioProtect's technology platform caters to a wide range of applications for unmet clinical needs.

Companion Medical is a medical device company headquartered in San Diego that develops a wireless insulin delivery system called InPen. The system combines a Bluetooth‑enabled insulin pen with a mobile application that calculates optimal dosing, records injection history, monitors insulin temperature, displays the last dose and insulin‑on‑board, and sends reports to health‑care providers. Founded in 2013, the company has leveraged its expertise in medical devices and critical systems to improve diabetes care. As of 2020, Companion Medical operates as a subsidiary of Medtronic.

Sinovation Medical specializes in the development of advanced medical robot technology and intelligent medical products. The company designs innovative medical devices aimed at delivering enhanced precision care. Their surgical robots employ clinical computer visioning technology to offer precise solutions for doctors and medical institutions. These products are primarily used in neurosurgery, addressing conditions such as epilepsy, Parkinson's disease, cerebral hemorrhage, and intracranial tumors. Sinovation Medical provides reliable medical robotics to clients, focusing on improving the accuracy and effectiveness of surgical procedures.

Medicrea is a specialized spinal implant company committed to delivering innovative technologies aimed at improving patient outcomes in spinal surgery. With over 18 years of experience, the company designs, develops, and manufactures a comprehensive range of patented products. Its offerings include personalized analytical services and implant systems, such as the UNiD Adaptive Spine Intelligence technology, as well as various spinal implant ranges, including the PASS Range, Cervical Range, and TH-LUMBAR Range. These products are intended to provide long-lasting pain relief and enhance the effectiveness of medical professionals in treating spinal conditions.

Stimgenics is a private company that pioneered a novel spinal cord stimulation waveform known as Differential Target Multiplexed (DTM) Spinal Cord Stimulation.

AV Medical Technologies is a medical device company focused on developing catheter-based interventions specifically for dialysis patients undergoing routine angioplasty procedures. Its flagship product, the Chameleon PTA balloon catheter, incorporates Supervision technology, which enables targeted injection of diagnostic fluids for enhanced visualization during procedures. This innovative approach allows physicians to determine the status of the balloon—whether inflated or deflated—while maintaining wire position, thereby improving procedural efficiency and safety for both patients and operators. The Chameleon catheter has undergone clinical testing in various dialysis access procedures, demonstrating its potential to enhance patient care in this critical medical area.

Saluda Medical is a medical device company specializing in closed-loop neuromodulation therapies for chronic neurological conditions. Founded in 2010 and headquartered in Australia, the company develops innovative devices like Evoke, designed to optimize neural stimulation based on real-time feedback.

EPIX Therapeutics, Inc. is a medical device company focused on developing innovative temperature-sensing irrigated radiofrequency ablation catheters for treating atrial fibrillation and other cardiac arrhythmias. The company utilizes its proprietary TempaSure technology, which employs microwave radiometry to provide real-time assessment of temperature within the heart, allowing physicians to accurately control lesion formation and enhance clinical outcomes. Founded in 2007 and headquartered in Santa Clara, California, EPIX Therapeutics was previously known as Advanced Cardiac Therapeutics, Inc. and rebranded in August 2018. The company has established strategic partnerships with industry leaders, including Abbott Laboratories and Hansen Medical Inc., to further advance its catheter-based systems aimed at improving the management of irregular heart rhythms. EPIX Therapeutics operates as a subsidiary of Medtronic plc.

Mazor Robotics, founded in 2001 and headquartered in Caesarea, Israel, specializes in developing, producing, and marketing medical devices for orthopedic and neurosurgical procedures. The company's primary focus is on surgical robotic-guidance systems that enhance precision and minimize invasiveness during complex surgeries. Their flagship products include the Mazor X and Renaissance systems, which are used extensively in spine surgeries such as fusion, correction of spinal deformities, biopsy collection, tumor excision, and cement augmentations. These systems aim to provide a safer surgical environment for patients, surgeons, and operating room staff by transforming traditional freehand procedures into highly accurate, state-of-the-art operations with better clinical outcomes.

MC10, Inc. is a company that specializes in developing wearable medical sensors designed to collect clinical-grade biometric and physiological data. Founded in 2008 and based in Lexington, Massachusetts, the company offers a range of innovative products, including BioStamp nPoint for vital signs and activity monitoring, Kintinuum for orthopedic rehabilitation, WiSP for cardiac monitoring, and BioStampMD, a conformal sensor that gathers both objective and subjective health data. MC10 employs advanced flexible electronics technology, allowing its devices to bend and stretch with the body, ensuring comfort and ease of use. The company focuses on enhancing human capabilities and improving health insights through discreet, location-specific sensing that captures real-world data on muscle activation and movement, with applications extending across various sectors including sports, military, and energy.

Nanos Medical specializes in the research, development, manufacturing, and sales of disposable medical devices, primarily targeting the cardiovascular and ear, nose, and throat (ENT) fields. The company offers a range of innovative products, including sinus balloon catheters, eustachian tube balloons, disposable nasopharyngeal airways, nasolacrimal balloons, and drug-eluting stents for sinus applications. Through its advanced medical devices, Nanos Medical aims to enhance treatment options for hospitals and patients, contributing to improved healthcare outcomes.

Yosemite Clinic is a comprehensive medical facility located in Central Pudong, Shanghai, offering a wide range of walk-in medical services. The clinic specializes in various fields, including family and internal medicine, surgery, orthopedics, dermatology, medical cosmetology, dentistry, gynecology, pediatrics, ophthalmology, and rehabilitation medicine. Equipped with advanced technology, Yosemite Clinic features state-of-the-art facilities such as CT, X-ray, ultrasound, and operating rooms, ensuring high-quality care. The clinic's diverse team of medical professionals, hailing from both China and around the globe, allows it to provide services in multiple languages, including English, Japanese, Malay, Mandarin Chinese, and Cantonese. By combining a multidisciplinary approach with modern medical practices, Yosemite Clinic aims to meet the diverse healthcare needs of its patients effectively.

VisionSense is a company focused on developing innovative visualization solutions for minimally invasive surgery (MIS). By utilizing advanced sensor technology and proprietary software, VisionSense provides a system that offers natural stereoscopic sight, delivering depth perception and 3D-HD resolution images. This technology allows for maneuvering flexibility through the smallest access points, addressing the limitations of traditional 2D (monocular) imaging that often hinders a surgeon's perspective. With enhanced tissue understanding and improved hand-eye coordination, surgeons are empowered to perform more complex procedures with greater confidence, particularly when using advanced articulating surgical tools.

FIRE1 is an Irish-based company specializing in the development of innovative therapeutic devices. Its flagship product is a remote monitoring system designed to enhance heart failure patients' lives by providing real-time data to healthcare providers, facilitating early detection and proactive interventions.

AEGEA Medical, Inc. is a medical technology company based in Menlo Park, California, that specializes in innovative treatments for women's health. The company has developed a water vapor ablation system, known as Mara, which is designed for the in-office treatment of heavy menstrual bleeding, specifically menorrhagia. This FDA-approved technology utilizes adaptive vapor ablation to deliver safe and effective endometrial ablation in a simple procedure that takes only minutes. AEGEA Medical aims to expand treatment options for a broader range of patients while ensuring convenience and confidence for physicians performing these office-based procedures. The company was incorporated in 2007 and continues to focus on enhancing patient outcomes in women's healthcare.

Crospon Limited is a medical device company focused on developing minimally invasive technologies for imaging and assisting surgeries in the esophagus and stomach. Founded in 2006 and based in Galway, Ireland, Crospon offers a range of products, including the EndoFLIP imaging system, which measures the dimensions and function of hollow organs and sphincteric regions. Its product lineup also includes measurement and dilation catheters, along with various endoscopic and laparoscopic accessories. Crospon's technologies are utilized in applications such as upper gastrodiagnostics, bariatric surgery, upper GI imaging, cardiology, therapeutic endoscopy, and colorectal imaging. The company distributes its products across multiple regions, including the United States, Europe, and parts of Africa and Latin America. As of December 2017, Crospon operates as a subsidiary of Medtronic plc.

Mazor Robotics, founded in 2001 and headquartered in Caesarea, Israel, specializes in developing, producing, and marketing medical devices for orthopedic and neurosurgical procedures. The company's primary focus is on surgical robotic-guidance systems that enhance precision and minimize invasiveness during complex surgeries. Their flagship products include the Mazor X and Renaissance systems, which are used extensively in spine surgeries such as fusion, correction of spinal deformities, biopsy collection, tumor excision, and cement augmentations. These systems aim to provide a safer surgical environment for patients, surgeons, and operating room staff by transforming traditional freehand procedures into highly accurate, state-of-the-art operations with better clinical outcomes.

SetPoint Medical Corporation is a clinical-stage medical device company developing implantable neuromodulation therapies to treat chronic inflammatory and autoimmune diseases. Its platform uses vagus nerve stimulation to activate the body's inflammatory reflex, aiming to produce a systemic immune-restorative effect and offer an alternative to drug therapy for conditions such as rheumatoid arthritis and inflammatory bowel disease. Based in Valencia, California.

Glooko develops a remote patient-monitoring platform for individuals with diabetes. It integrates with diabetes devices, fitness wearables, and activity trackers to capture data and provide reports, aiming to drive behavior change and improve health outcomes. The platform facilitates communication between patients and healthcare providers, enhancing care. Glooko is available on Android and iOS.

EarLens is a privately held medical technology company focused on enhancing the hearing experience for individuals with hearing loss. The firm has pioneered the Earlens Contact Hearing Solution, a groundbreaking device that directly activates the natural hearing process. This innovative system utilizes low-frequency radio signals and a small lens placed on the eardrum to vibrate it, allowing for superior sound quality and a broader bandwidth than traditional hearing aids. Unlike conventional devices that amplify sound, the Earlens solution delivers sound directly to the eardrum, thereby minimizing feedback and ensuring clear hearing in various environments. The second generation of this technology received FDA clearance in 2019, marking a significant advancement in the standard of care for hearing performance.

Saluda Medical is a medical device company specializing in closed-loop neuromodulation therapies for chronic neurological conditions. Founded in 2010 and headquartered in Australia, the company develops innovative devices like Evoke, designed to optimize neural stimulation based on real-time feedback.

Forerunner Medical (Shanghai) Co., Ltd., established in 2009, specializes in the development and manufacturing of innovative medical devices aimed at minimally invasive treatments. The company focuses on creating low-temperature plasma radio-frequency generators and electrodes specifically designed for sports medicine and tumor treatment. By leveraging extensive domestic clinical data and advanced technology, Forerunner Medical aims to meet both domestic and global healthcare needs. The organization emphasizes the quality and safety of its products, ensuring high performance, aesthetic appeal, and user convenience. Its commitment to excellence is reflected in its state-of-the-art production equipment and professional expertise, which contribute to its competitive advantage in the medical device industry.

MD Start SA is a medical technology incubator based in Lausanne, Switzerland, that specializes in transforming innovative ideas into viable medical solutions. Founded in 2009, the company creates, develops, and operates medical projects, effectively turning them into new companies. MD Start employs both strategic and hands-on approaches to guide these projects through the investment stage and into commercial development. The firm collaborates with notable partners in the medical device sector, including Medtronic, Sofinnova Partners, and Versant Ventures, among others. Through its focused efforts, MD Start aims to support the growth of medical device start-ups and facilitate the advancement of healthcare technologies.

Mazor Robotics, founded in 2001 and headquartered in Caesarea, Israel, specializes in developing, producing, and marketing medical devices for orthopedic and neurosurgical procedures. The company's primary focus is on surgical robotic-guidance systems that enhance precision and minimize invasiveness during complex surgeries. Their flagship products include the Mazor X and Renaissance systems, which are used extensively in spine surgeries such as fusion, correction of spinal deformities, biopsy collection, tumor excision, and cement augmentations. These systems aim to provide a safer surgical environment for patients, surgeons, and operating room staff by transforming traditional freehand procedures into highly accurate, state-of-the-art operations with better clinical outcomes.

HeartWare International, Inc. specializes in the development and manufacturing of small implantable heart pumps, also known as ventricular assist devices, aimed at treating advanced heart failure. The company offers the HeartWare Ventricular Assist System, which comprises a left ventricular assist device, patient accessories, and surgical tools designed to provide critical circulatory support for patients in the advanced stages of heart failure. Additionally, HeartWare is working on the Miniaturized Ventricular Assist Device, intended for chronic heart failure patients. The company markets its products through clinical studies in the United States and directly to cardiac centers and hospitals worldwide. Headquartered in Framingham, Massachusetts, HeartWare is committed to improving the quality of life for patients suffering from severe heart conditions.

EarLens is a privately held medical technology company focused on enhancing the hearing experience for individuals with hearing loss. The firm has pioneered the Earlens Contact Hearing Solution, a groundbreaking device that directly activates the natural hearing process. This innovative system utilizes low-frequency radio signals and a small lens placed on the eardrum to vibrate it, allowing for superior sound quality and a broader bandwidth than traditional hearing aids. Unlike conventional devices that amplify sound, the Earlens solution delivers sound directly to the eardrum, thereby minimizing feedback and ensuring clear hearing in various environments. The second generation of this technology received FDA clearance in 2019, marking a significant advancement in the standard of care for hearing performance.

Responsive Orthopedics is a Minneapolis-based medical device company founded in 2013 that designs, develops, and sells knee and hip implant systems for hospitals and physician practices. It focuses on affordable solutions for providers participating in government or federal programs aimed at reducing procedure costs and provides logistical support to healthcare facilities. The company markets total knee systems and related devices and offers distribution and support services to clinicians. In 2016, Responsive Orthopedics was acquired by Medtronic.

Gynaecology has been rapidly built around Smith & Nephew's resection technologies and comprises, primarily, the TRUCLEAR◊ System for the hysteroscopic resection and removal of uterine tissue. Gynaecology delivered revenue of $56 million in 2015, representing a little over 1% of Group revenue.

Bellco is an Italian company recognized as a pioneer in the field of haemodialysis, dedicated to addressing the needs of patients and healthcare professionals through innovation and research. The company specializes in the manufacturing and distribution of medical devices for renal care, including dialyzers, fluids, machines, and hematic lines designed for the treatment of kidney diseases. In addition to its focus on haemodialysis, Bellco develops equipment for extra-corporeal blood filtration, supporting advanced therapies in Nephrology, Intensive Care, and Cardiology. Through its commitment to technological advancement, Bellco continues to play a significant role in improving patient care in the realm of renal health.

Aircraft Medical Limited is a developer and producer of handheld medical devices specializing in anesthesia and critical care. Founded in 2001 and based in Edinburgh, United Kingdom, the company is known for its flagship product, the McGRATH, a portable video laryngoscope designed to enhance the intubation process. Aircraft Medical's innovations aim to provide life-saving technology for anesthesia professionals, focusing on reducing patient trauma, minimizing cross-contamination, and improving communication and efficiency in clinical training. The company distributes its products through partners across various regions, including the United States, Canada, the United Kingdom, and several countries in Europe and Australasia. Aircraft Medical was formerly known as Smartscope MD Ltd. and adopted its current name in February 2004. As of November 2015, it operates as a subsidiary of Medtronic plc.

Lazarus Effect is a medical device company dedicated to creating innovative interventional devices designed to enhance the removal of blood clots. The company is focused on developing a comprehensive portfolio of vascular-device products leveraging a patented wire-frame technology platform. Currently, Lazarus Effect holds five issued US patents along with several pending patent applications both in the US and internationally. The company’s notable products include the Lazarus Funnel™ Guide Catheter and the Lazarus ReCover devices, which have received CE Mark approval for use in Europe, while the Funnel is also cleared for use in the United States. The Lazarus Cover device is in the process of obtaining CE Mark approval. However, the ReCover and Cover devices are not yet authorized for sale in the United States.

SetPoint Medical Corporation is a clinical-stage medical device company developing implantable neuromodulation therapies to treat chronic inflammatory and autoimmune diseases. Its platform uses vagus nerve stimulation to activate the body's inflammatory reflex, aiming to produce a systemic immune-restorative effect and offer an alternative to drug therapy for conditions such as rheumatoid arthritis and inflammatory bowel disease. Based in Valencia, California.

Twelve manufactures medical devices. It was formerly known as Foundry Newco XII, Inc. The company was incorporated in 2009 and is based in Menlo Park, California.

CardioInsight Technologies Inc. is a medical device company based in Cleveland, Ohio, specializing in non-invasive cardiac mapping systems. The company has developed a technology called Electrocardiographic Mapping (ECM), which generates three-dimensional images of the heart's electrical activity by integrating body surface electrical data with anatomical data obtained from CT scans. The CardioInsight system employs a single-use disposable multi-sensor vest to capture electrical signals from the body surface, enabling the creation of detailed epicardial 3D electroanatomic maps and virtual electrograms. This innovative approach allows physicians to visualize real-time cardiac electrical activity and enhances the accuracy of diagnosing and treating conditions such as arrhythmias and congestive heart failure. CardioInsight's technology has been validated through over 260 patient studies, demonstrating its effectiveness in guiding therapeutic interventions. Founded in 2006, the company operates as a subsidiary of Medtronic plc.

Aptus Endosystems, Inc. is a medical device company focused on developing advanced solutions for endovascular aneurysm repair (EVAR). Founded in 2002 and based in Sunnyvale, California, the company has created innovative technologies such as the Heli-FX EndoAnchor system, which provides a durable method for treating abdominal and thoracic aortic aneurysms. This system employs unique helical staple technology that allows for independent fixation of endografts, mimicking the precision of open surgical suturing while facilitating minimally invasive procedures. Additionally, Aptus Endosystems offers the Aptus TourGuide, a steerable sheath designed to enhance access and delivery of peripheral vascular products. The company's products are distributed in key markets including the United States and several European countries, and the Aptus Endovascular AAA Repair Systems hold CE Marking for distribution within the European Union.

AEGEA Medical, Inc. is a medical technology company based in Menlo Park, California, that specializes in innovative treatments for women's health. The company has developed a water vapor ablation system, known as Mara, which is designed for the in-office treatment of heavy menstrual bleeding, specifically menorrhagia. This FDA-approved technology utilizes adaptive vapor ablation to deliver safe and effective endometrial ablation in a simple procedure that takes only minutes. AEGEA Medical aims to expand treatment options for a broader range of patients while ensuring convenience and confidence for physicians performing these office-based procedures. The company was incorporated in 2007 and continues to focus on enhancing patient outcomes in women's healthcare.

Ortho Kinematics, Inc. is a healthcare diagnostics company based in Austin, Texas, specializing in spine imaging informatics. Founded in 2006, the company develops innovative diagnostic technology solutions for assessing spinal health. Its flagship product, the KineGraph Vertebral Motion Analyzer, employs fluoroscopy to capture spine motion and produce detailed patient-specific graphs that assist clinicians in diagnosing spinal instability and related conditions. In addition to its diagnostic devices, Ortho Kinematics offers comprehensive spine diagnostic imaging services through its imaging center in Austin, providing valuable information to healthcare professionals for the effective treatment of back and neck pain.

DreaMed Diabetes, Ltd. is an Israel-based company founded in 2014 that specializes in developing innovative solutions for diabetes treatment and management. The company has created a portfolio that includes Glucositter, a closed-loop insulin delivery system designed to monitor glucose levels in real-time and optimize insulin adjustments. DreaMed Diabetes is recognized for commercializing the first artificial pancreas technology, which has been validated in leading medical journals. It has also pioneered decision support tools for diabetes management, being the first company to receive FDA clearance for a system utilizing data from continuous glucose monitors and insulin pumps. Its Advisor Pro software, developed by diabetes professionals, leverages artificial intelligence to enable healthcare providers to quickly analyze patient data and recommend personalized treatment plans. Through frequent insulin titration and online monitoring, DreaMed Diabetes aims to enhance patient care by reducing A1C levels and the risk of complications, ensuring that all patients receive high-quality treatment regardless of their location or caregiver.

Sophono, Inc. is a medical device manufacturer based in Boulder, Colorado, specializing in magnetic bone conduction hearing devices designed for patients with conductive hearing loss, mixed hearing loss, and single-sided deafness. Founded in 2009, the company produces innovative products such as the Alpha 1 and Alpha 2 MPO hearing devices, which utilize a unique abutment-free design that allows for the implantation of sound processors beneath the skin. These devices aim to provide effective solutions for individuals experiencing severe to profound hearing impairment. Sophono sells its products through clinics and operates as a subsidiary of Medtronic plc as of 2015.

Glooko develops a remote patient-monitoring platform for individuals with diabetes. It integrates with diabetes devices, fitness wearables, and activity trackers to capture data and provide reports, aiming to drive behavior change and improve health outcomes. The platform facilitates communication between patients and healthcare providers, enhancing care. Glooko is available on Android and iOS.

Advanced Uro-Solutions is a medical device company specializing in the development and manufacture of innovative solutions for various health conditions. The company's flagship product is the NURO percutaneous tibial nerve stimulation system, which includes a compact external stimulator and a reusable lead designed to provide temporary stimulation to the tibial nerve. This system addresses urinary urgency and incontinence, as well as other related disorders. In addition to its core focus on urinary health, Advanced Uro-Solutions also develops medical devices for bowel control disorders, cardiac rhythm disorders, and neurological conditions, reflecting its commitment to enhancing patient care across multiple health issues.

AcuFocus, Inc. is an ophthalmic medical device company based in Irvine, California, specializing in small aperture technologies aimed at improving near vision. Founded in 2001, the company develops and markets innovative solutions for presbyopia, including the KAMRA inlay, which helps patients restore their near vision without compromising distance vision. Additionally, AcuFocus offers the IC-8 IOL, a small aperture lens designed for cataract patients, providing a broad range of vision from near to far distances. The company also produces the AcuTarget HD, a diagnostic and surgical planning instrument that assists in the optimal treatment selection for various eye conditions such as LASIK, cataracts, and dry eye. AcuFocus distributes its products through partners across the Americas, Asia-Pacific, Europe, and the Middle East, serving both physicians and patients in the vision care market.

Founded by Dr. Eugenio Cremascoli, the main business of NGC Medical Focuses are: Project planning, manufacturing and marketing of medical and surgical devices Import and distribution in national territory of medical devices, medical data management systems, medical communications database for remote access and medical equipment Design and turnkey implementation of Surgery Units, Intensive Care, Hemodynamics, Electrophysiology and Intervention Radiology Laboratories In-service management of Surgical Suites, Intensive Care, Hemodynamics, Electrophysiology and Intervention Radiology Laboratories Design and implementation of Information Management Software packages unifying the administrative and clinical departments within at single interface

Sapiens Steering Brain Stimulation GmbH is a medical device company focused on advancing deep brain stimulation (DBS) therapy. Founded in 2011 as a spin-out of Royal Philips Electronics, Sapiens operates from offices in Eindhoven, the Netherlands, and Munich, Germany. The company is dedicated to developing a high-resolution, MRI-compatible DBS system designed to enhance patient comfort and improve therapeutic outcomes, particularly for individuals with Parkinson's disease. Sapiens’ innovative approach includes a unique steering brain stimulation system and image-guided programming, both of which are based on patented technologies.

Visualase, Inc., established in 2005 as a spin-off from BioTex, Inc., is a privately held company based in Houston, Texas. It specializes in the development of advanced laser and image-guided technologies for thermal ablation markets, focusing on the treatment of cancer or other malignancies using innovative laser and MRI-based guidance systems.

Covidien plc is a healthcare company involved in the development, manufacture, and sale of a wide range of products intended for clinical and home use, aimed at improving patient outcomes while reducing healthcare costs. The company operates through four primary segments: Medical Devices, Imaging Solutions, Pharmaceutical Products, and Medical Supplies. Within the Medical Devices segment, Covidien produces endomechanical instruments, soft tissue repair products, energy devices, oximetry and monitoring products, airway and ventilation products, vascular devices, and SharpSafety products. The Imaging Solutions segment focuses on radiopharmaceuticals and contrast products, while the Pharmaceutical Products segment encompasses dosage pharmaceuticals and active pharmaceutical ingredients. Finally, the Medical Supplies segment includes nursing care products and medical surgical products. Covidien collaborates with medical professionals to enhance the quality of life for patients through its innovative healthcare solutions.

Corventis is a medical technology company focused on enhancing clinical outcomes and reducing healthcare costs through the early detection of cardiovascular events. Its primary product is a non-invasive monitor that measures various aspects of heart function, enabling proactive management of cardiovascular diseases. By providing patients with tools that support an active lifestyle, Corventis aims to improve overall health while addressing critical issues in cardiovascular care.

TyRx specializes in the development of resorbable polymeric biomaterials. It offers PIVIT CRM, an antibacterial mesh pouch protecting implantable cardiac devices from microbial infections during and post-surgery, and AIGISRx Flat, an antibacterial product safeguarding pacemakers and defibrillators against infections.

CardioInsight Technologies Inc. is a medical device company based in Cleveland, Ohio, specializing in non-invasive cardiac mapping systems. The company has developed a technology called Electrocardiographic Mapping (ECM), which generates three-dimensional images of the heart's electrical activity by integrating body surface electrical data with anatomical data obtained from CT scans. The CardioInsight system employs a single-use disposable multi-sensor vest to capture electrical signals from the body surface, enabling the creation of detailed epicardial 3D electroanatomic maps and virtual electrograms. This innovative approach allows physicians to visualize real-time cardiac electrical activity and enhances the accuracy of diagnosing and treating conditions such as arrhythmias and congestive heart failure. CardioInsight's technology has been validated through over 260 patient studies, demonstrating its effectiveness in guiding therapeutic interventions. Founded in 2006, the company operates as a subsidiary of Medtronic plc.

Cardiocom is a leading provider of telemedicine solutions focused on daily remote patient monitoring and disease management. The company specializes in the manufacturing and distribution of health monitoring products, including telehealth devices for conditions such as congestive heart failure, diabetes, obesity, hypertension, chronic obstructive pulmonary disease, and asthma. Cardiocom equips health professionals with home telemonitoring equipment and comprehensive telehealth services aimed at identifying symptomatic patients and facilitating early interventions to reduce unnecessary hospitalizations. The company offers tailored health monitoring options, including the Cardiocom OMNIVISOR PRO® Patient Management System, TELESCALE® for managing congestive heart failure, and COMMANDER for patients with multiple chronic conditions. Through its proactive solutions, Cardiocom enhances patient quality of life while providing cost savings to health management organizations.

Founded in 2003, Intersect ENT is a medical device company based in Menlo Park, California. It specializes in developing innovative therapies for Ear, Nose, and Throat surgeons to enhance patient care, focusing on treatments for chronic rhinosinusitis.

MC10, Inc. is a company that specializes in developing wearable medical sensors designed to collect clinical-grade biometric and physiological data. Founded in 2008 and based in Lexington, Massachusetts, the company offers a range of innovative products, including BioStamp nPoint for vital signs and activity monitoring, Kintinuum for orthopedic rehabilitation, WiSP for cardiac monitoring, and BioStampMD, a conformal sensor that gathers both objective and subjective health data. MC10 employs advanced flexible electronics technology, allowing its devices to bend and stretch with the body, ensuring comfort and ease of use. The company focuses on enhancing human capabilities and improving health insights through discreet, location-specific sensing that captures real-world data on muscle activation and movement, with applications extending across various sectors including sports, military, and energy.

Mitralign is a privately held medical device company based in a suburb of Boston, Massachusetts. It specializes in developing catheter-based technologies for the percutaneous treatment of functional mitral regurgitation, a global and life-threatening cardiac condition. The company's innovative Mitralign system mimics surgical annuloplasty by delivering a series of implants directly into the mitral annulus via a catheter, reducing its size and improving valve function. Mitralign is backed by top-tier venture capitalists and has strategic investments from major cardiovascular device companies.

Visualase, Inc., established in 2005 as a spin-off from BioTex, Inc., is a privately held company based in Houston, Texas. It specializes in the development of advanced laser and image-guided technologies for thermal ablation markets, focusing on the treatment of cancer or other malignancies using innovative laser and MRI-based guidance systems.

CardioInsight Technologies Inc. is a medical device company based in Cleveland, Ohio, specializing in non-invasive cardiac mapping systems. The company has developed a technology called Electrocardiographic Mapping (ECM), which generates three-dimensional images of the heart's electrical activity by integrating body surface electrical data with anatomical data obtained from CT scans. The CardioInsight system employs a single-use disposable multi-sensor vest to capture electrical signals from the body surface, enabling the creation of detailed epicardial 3D electroanatomic maps and virtual electrograms. This innovative approach allows physicians to visualize real-time cardiac electrical activity and enhances the accuracy of diagnosing and treating conditions such as arrhythmias and congestive heart failure. CardioInsight's technology has been validated through over 260 patient studies, demonstrating its effectiveness in guiding therapeutic interventions. Founded in 2006, the company operates as a subsidiary of Medtronic plc.

AcuFocus, Inc. is an ophthalmic medical device company based in Irvine, California, specializing in small aperture technologies aimed at improving near vision. Founded in 2001, the company develops and markets innovative solutions for presbyopia, including the KAMRA inlay, which helps patients restore their near vision without compromising distance vision. Additionally, AcuFocus offers the IC-8 IOL, a small aperture lens designed for cataract patients, providing a broad range of vision from near to far distances. The company also produces the AcuTarget HD, a diagnostic and surgical planning instrument that assists in the optimal treatment selection for various eye conditions such as LASIK, cataracts, and dry eye. AcuFocus distributes its products through partners across the Americas, Asia-Pacific, Europe, and the Middle East, serving both physicians and patients in the vision care market.

Functional Neuromodulation, Ltd. is a medical technology company focused on developing neuromodulation therapies for cognitive and memory disorders, particularly Alzheimer's disease and mild cognitive impairment. Founded in 2010, the company is headquartered in Minneapolis, Minnesota, with an additional office in Toronto, Canada. Its primary offering is deep brain stimulation (DBS) technology, which utilizes a surgically implanted medical device to deliver mild electrical pulses to specific areas of the brain. This approach aims to enhance neural activity and modulate the brain's memory circuits, helping patients diagnosed with Alzheimer’s and other cognitive disorders to maintain a healthier quality of life.

PEAK Surgical is a medical device company based in Palo Alto, California, specializing in innovative surgical tools designed to enhance precision and control during surgical procedures. The company offers the PEAK Surgery System, which includes a range of disposable cutting devices that combine the accuracy of a scalpel with the bleeding control typically associated with traditional electrosurgery, minimizing collateral damage. This system is approved for use in various surgical specialties, including general, plastic and reconstructive, ENT, gynecologic, orthopedic, arthroscopic, spinal, and neurological procedures in the United States, as well as for general surgery in the European Union. PEAK Surgical aims to address critical needs in the surgical market by providing advanced solutions that improve patient outcomes.

Spinal Modulation, Inc., headquartered in Menlo Park, California, specializes in the development of advanced medical devices aimed at treating chronic pain. The company's flagship product, the Axium Neurostimulator System, represents a novel approach to pain management through intraspinal neuromodulation. This system specifically stimulates the dorsal root ganglion (DRG), providing an innovative alternative for patients suffering from chronic intractable leg pain and other challenging pain conditions such as those affecting the back and foot. By effectively targeting the DRG, the Axium system offers the ability to deliver adjustable therapies that can be tailored to address both broad and localized pain areas, while minimizing discomfort associated with traditional spinal cord stimulators. This technology addresses a significant unmet need in pain management, aiming to alleviate the burden on patients and healthcare systems alike.

PhysioSonics, a development-stage device company based in Washington, focuses on ultrasound imaging to monitor blood flow in the brain.

Ardian, established in 1996, is a France-based asset manager offering global investment management services. It primarily focuses on fund of funds (55.21%), followed by direct funds (19.79%), infrastructure (16.67%), and private debt (7.29%), with a minor allocation to real estate (1.04%). Ardian invests across various sectors, including food value chain, healthcare, technology, and industrials, with a presence in Europe and North America.

Osteotech is focused on the development, manufacturing, and marketing of biologic, biomaterial, and device systems for musculoskeletal surgeries. It facilitates spinal, trauma, and total joint revision procedures. Osteotech was acquired by Medtronic in November 2010. It was founded in 1986 in Eatontown, New Jersey.

Founded in 2003, Intersect ENT is a medical device company based in Menlo Park, California. It specializes in developing innovative therapies for Ear, Nose, and Throat surgeons to enhance patient care, focusing on treatments for chronic rhinosinusitis.

Axon Systems is the designer and manufacturer of various NIM Eclipse nerve monitoring systems, which have been marketed and sold in the United States by the Spinal and Biologics business at Medtronic for the past three years. These devices are used in surgery to enhance patient safety by protecting delicate nerves during implant procedures. Axon Systems has introduced an impressive number of "firsts" in the field of neuromonitoring, including: 16 and 32 channel simultaneous multimodality systems, integrated transcranial MEP, microscope and vital signs views, and integrated TCD and pulse oximetery.

CardioMEMS is a medical device company specializing in wireless monitoring solutions for severe chronic cardiovascular conditions. Their proprietary technology involves miniature sensors implanted via minimally invasive procedures, transmitting vital data like cardiac output, blood pressure, and heart rate to enhance patient management, particularly for heart failure, hypertension, and aneurysms.

ATS Medical, doing business as Medtronic ATS Medical, Inc., is a medical device manufacturer that specializes in products for cardiovascular surgery. Mechanical heart valves, aortic valve graft prostheses, and other cardiovascular accessories are available from the company. Medtronic ATS Medical markets and distributes its products to the healthcare industry worldwide. ATS Medical was acquired by Medtronic on August 12, 2010

Atreo Medical is a company focused on developing innovative medical tools that enhance resuscitation efforts. Its flagship product, the CPRGlove, is designed to assist users in performing high-quality cardiopulmonary resuscitation (CPR) both in clinical settings and in emergencies outside of hospitals. By guiding users through the CPR process, the device aims to empower individuals to deliver effective first aid and improve survival rates in life-threatening situations.

Invatec is a European company specializing in the development and commercialization of interventional products for cardiovascular treatment, focusing on coronary and peripheral applications. Founded in 1996 by Andrea Venturelli and Stefan Widensohler, Invatec leverages advanced research and technology, collaborating with physicians and centers of excellence to enhance patient life expectancy and quality of life. The company offers a diverse portfolio of 35 product families, including drug-eluting balloons and solutions for critical limb ischemia and carotid artery stenting, which are sold in over 70 countries. Invatec's expertise encompasses polymer processing, metallurgy, surface treatments, and drug coatings, supported by a fully integrated in-house design, development, manufacturing, and assembly process. The company employs approximately 900 people, primarily based in Brescia, Italy, and Frauenfeld, Switzerland.

MicroCHIPS Biotech, Inc. specializes in developing a microchip-based implant designed for drug delivery applications across various therapeutic areas, including osteoporosis, diabetes, multiple sclerosis, women’s contraception, and pain management. This innovative implant can store and release precise doses of medication over extended periods, offering an alternative to traditional therapies that rely on frequent injections. The implant is surgically placed under the skin during a minimally invasive procedure and can be wirelessly activated or deactivated by healthcare providers or patients. Additionally, the device allows for real-time adjustments to the drug dosage and frequency, catering to the specific needs of each patient. Established in 1999 and headquartered in Lexington, Massachusetts, MicroCHIPS operates as a subsidiary of Daré Bioscience, Inc.

GI Dynamics, Inc. is a medical device company that specializes in designing, developing, and manufacturing non-surgical therapies for the treatment of type 2 diabetes and obesity. The company’s primary product, EndoBarrier, is aimed at helping patients manage their condition and reduce obesity without the need for surgical intervention. GI Dynamics serves healthcare providers and third-party distributors, selling its products mainly in Europe, the Middle East, the Asia Pacific, and South America. Founded in 2003, the company is headquartered in Lexington, Massachusetts.

CardioMEMS is a medical device company specializing in wireless monitoring solutions for severe chronic cardiovascular conditions. Their proprietary technology involves miniature sensors implanted via minimally invasive procedures, transmitting vital data like cardiac output, blood pressure, and heart rate to enhance patient management, particularly for heart failure, hypertension, and aneurysms.

PreciSense A/S, a Denmark-based development company focused on continuous glucose monitoring (CGM) technology.

CoreValve is a private company founded in 2001 by Dr. Jacques Seguin, a cardiac surgeon, with the aim of innovating heart valve replacement technologies. The company specializes in developing catheter-based aortic valve replacement products, allowing for the replacement of failing aortic heart valves without the need for traditional surgical access. CoreValve has successfully performed the ReValving™ procedure on over 200 patients, demonstrating the efficacy of its technology. While the current focus is on percutaneous aortic valve replacement, CoreValve plans to expand its efforts to include other minimally invasive treatments for structural heart disease. Headquartered in Irvine, California, the company is positioned in a region known for its advancements in heart valve technologies.

Ardian, established in 1996, is a France-based asset manager offering global investment management services. It primarily focuses on fund of funds (55.21%), followed by direct funds (19.79%), infrastructure (16.67%), and private debt (7.29%), with a minor allocation to real estate (1.04%). Ardian invests across various sectors, including food value chain, healthcare, technology, and industrials, with a presence in Europe and North America.

Ventor Technologies is a privately-held company based in Netanya, Israel. Dedicated to the development of minimally-invasive replacement aortic valves, Ventor has developed the transapically-implantable Ventor Embracer™,* which is under clinical investigation in Europe. The transapical approach is particularly suited to the minimally-invasive skills of cardiac surgeons, and provides a valuable option when a non-femoral approach is preferred because of factors such as peripheral artery disease.

Ablation Frontiers, Inc. is a medical device company located in Carlsbad, California, focused on developing innovative solutions for individuals suffering from atrial fibrillation (AF) and other cardiac arrhythmias. The company specializes in manufacturing mapping and ablation catheters, radiofrequency generators, and related accessories designed to assist healthcare professionals in effectively treating these conditions. In 2006, Ablation Frontiers received CE Mark approval to market its catheter system and the GENius Radiofrequency Generator in the European Union for the treatment of supraventricular arrhythmias and atrioventricular node ablation. Currently, the company is conducting a clinical trial under a United States Food and Drug Administration investigational device exemption to secure approval for its catheter system for use in chronic AF in the U.S. However, its products are not yet approved for marketing or sales in the United States.

CryoCath Technologies is a medical device company that specializes in the development, manufacturing, and marketing of cryoablation catheter systems for treating cardiac arrhythmias, tumors, and other obstructions. The company's innovative systems consist of flexible and steerable catheters, which are operated through electromechanical consoles that deliver and recover refrigerants for minimally invasive procedures. Key products include electrophysiology devices such as the Achieve Mapping Catheter, Arctic Front, FlexCath, CryoConsole, Freezor, Freezor MAX, and Freezor Xtra. CryoCath Technologies distributes its products across Europe, North America, the Middle East, and the Russian Federation. Currently, it operates as a subsidiary of Medtronic, Inc.

Established in 1999, Restore Medical is a privately-held company focused on becoming the primary resource for physicians specializing in sleep and breathing disorders. Restore Medical has developed and markets proprietary implant technology which addresses such disorders as snoring and sleep apnea. The company's first product based on this technology, the patented Pillar™ System, received market clearance from the Food and Drug Administration in late 2002 and is currently available throughout the United States. Restore Medical also distributes other related high-quality products to the Ear, Nose and Throat physicians through our dedicated sales team. Located in St. Paul, Minnesota, Restore Medical manufactures the Pillar™ System in its onsite state-of-the-art Class 100,000 Clean Room. The company is ISO 9001 certified and utilizes an intranet-based quality and product development system. Restore currently employs a team of approximately 55 professionals.

NDI Medical, established in 2002 and based in Cleveland, Ohio, operates as a medical device incubator specializing in neurostimulation technologies. The company is dedicated to developing high-growth enterprises that aim to address significant unmet health needs. NDI Medical's team comprises experienced entrepreneurs, scientists, and physician advisors, along with experts in clinical and regulatory affairs, product development, quality assurance, and finance. By focusing on innovative neuro-device technologies, NDI Medical seeks to advance the field of medical devices and improve therapeutic outcomes for patients.

Arbor Surgical Technologies, Inc. located in Irvine and Portola Valley, CA (USA), is a privately held cardiovascular medical device company focused on the heart valve replacement market. Founded in 2002 by Dr. Thomas J. Fogarty and noted heart valve designer, Ernie Lane, Arbor is developing multiple technologies that have the potential to deliver significant clinical benefit to patients worldwide. Arbor intends to develop and commercialize its core technologies in varying combinations, giving the company the opportunity to create a portfolio of product offerings. Currently in clinical trials, Arbor is developing a tissue heart valve family of products designed for improved performance over existing valves and compatible implantation tools that simplify and speed valve replacement surgery.

Mitralign is a privately held medical device company based in a suburb of Boston, Massachusetts. It specializes in developing catheter-based technologies for the percutaneous treatment of functional mitral regurgitation, a global and life-threatening cardiac condition. The company's innovative Mitralign system mimics surgical annuloplasty by delivering a series of implants directly into the mitral annulus via a catheter, reducing its size and improving valve function. Mitralign is backed by top-tier venture capitalists and has strategic investments from major cardiovascular device companies.

REVA Medical, Inc. is a medical device company based in San Diego, California, established in 1998. The company specializes in developing and commercializing polymer-based bioresorbable products for vascular applications. Its primary offerings include the Fantom Encore, a bioresorbable vascular scaffold designed for the treatment of coronary artery disease, and the MOTIV scaffold for below-the-knee peripheral artery disease. REVA Medical's products utilize proprietary tyrosine-derived polymer technologies that support the healing of arteries while eventually dissolving in the body, thus restoring natural function. The Fantom Encore is marketed in several European countries, including Germany, Switzerland, and Italy. Initially founded as MD3, Inc., the company rebranded to REVA Medical, Inc. in March 2002.