Main Sequence Ventures

Main Sequence Ventures, established in 2017 and based in Eveleigh, Australia, is a venture capital firm that invests in early-stage companies developing deep tech or frontier technologies to address global challenges. The firm backs ambitious founders creating the next set of global industries, with investments supported by the Australian National Science Agency, CSIRO, the Australian Federal Government, and private investors. Main Sequence leverages world-class research from Australian public research organizations, including CSIRO and universities, to identify and nurture promising startups.

Bill Bartee

General Partner

Alezeia Brown

Investor

Martin Duursma

Partner

Danielle Haj Moussa

Analyst

Phil Morle

Partner

Gabrielle Munzer

Partner

Mike Nicholls

Partner

Jun Qu

Investor

Alejandra Romero

Analyst

Elaine Stead Ph.D

Principal

Mike Zimmerman

Partner

Past deals in Autonomous Vehicles

Arkeus

Venture Round in 2025
Arkeus is a technology company that specializes in the rapid development of autonomous optical systems for various surveillance and reconnaissance applications. They design, innovate, and fabricate these systems, which are optimized for use on surface sensors, aircraft, or drones, to support missions such as intelligence gathering, border protection, and search and rescue. Their solutions enable the defense industry to make informed decisions in challenging environments.

Breaker

Pre Seed Round in 2025
Breaker develops cutting-edge software that transforms the interaction between humans and machines. Our platform leverages advanced decision-making, natural language communication, and enhanced perception to enable sophisticated autonomous capabilities in machines previously only achievable with human oversight. Designed for diverse industries, Breakers’ software facilitates a new level of efficiency and versatility in uncrewed systems, promising to revolutionize the way autonomous assets operate and collaborate with humans. Our mission is to make intelligent, autonomous collaboration a reality, bridging the gap between human intuition and machine precision.

Arkeus

Seed Round in 2023
Arkeus is a technology company that specializes in the rapid development of autonomous optical systems for various surveillance and reconnaissance applications. They design, innovate, and fabricate these systems, which are optimized for use on surface sensors, aircraft, or drones, to support missions such as intelligence gathering, border protection, and search and rescue. Their solutions enable the defense industry to make informed decisions in challenging environments.

Advanced Navigation

Series B in 2022
Advanced Navigation, established in 2012 and based in Sydney, Australia, specializes in developing and manufacturing high-quality navigational technologies and robotics. The company's portfolio includes acoustic underwater navigation systems, GNSS/INS devices, MEMS AHRS, logging and post-processing units, satellite compasses, speed sensors, subsea antennas, and INS. With a background in mission-critical robotics and expertise spanning sensors, GNSS, inertial navigation, RF technologies, acoustics, robotics, AI, and algorithms, Advanced Navigation's products are designed to operate accurately under challenging conditions, serving clients in manufacturing and warehousing facilities to enhance process optimization and productivity.

Swoop Aero

Series B in 2022
Swoop Aero, established in 2017 and headquartered in Melbourne, Australia, specializes in drone-powered logistics services. The company aims to revolutionize air transportation networks by integrating drone logistics into the first and last mile of supply chains, enhancing their strength and agility. Swoop Aero offers two-way deliveries across diverse destinations, organizations, and providers, utilizing autonomous drones to transport essential supplies, even to locations otherwise inaccessible. Their services cater to various industries, including health, transport, disaster management, and search and rescue, with a mission to make access to the skies seamless for 1 billion people by 2030.

Emesent

Series A in 2022
Emesent specializes in developing drone technology for data collection and analysis in challenging underground environments. Its flagship product, Hovermap, enables drones to fly and map in GPS-denied areas like mines, enhancing safety, efficiency, and operational insights.

Baraja

Series B in 2021
Baraja is a deep technology company specializing in advanced LiDAR solutions for autonomous vehicles. It has developed a unique platform called Spectrum-Scan™, which employs a novel approach to light detection and ranging by utilizing prisms instead of traditional moving parts and mirrors. This innovative method refracts light through optics connected to a wavelength-tunable laser, allowing for enhanced scanning capabilities. As a result, Baraja's technology offers superior range, precision, and reliability, even in challenging environments. This advancement enables manufacturers of self-driving cars to achieve instantaneous multi-angle scanning with high detail and adaptability, positioning Baraja as a leader in the autonomous vehicle technology sector.

Advanced Navigation

Series A in 2019
Advanced Navigation, established in 2012 and based in Sydney, Australia, specializes in developing and manufacturing high-quality navigational technologies and robotics. The company's portfolio includes acoustic underwater navigation systems, GNSS/INS devices, MEMS AHRS, logging and post-processing units, satellite compasses, speed sensors, subsea antennas, and INS. With a background in mission-critical robotics and expertise spanning sensors, GNSS, inertial navigation, RF technologies, acoustics, robotics, AI, and algorithms, Advanced Navigation's products are designed to operate accurately under challenging conditions, serving clients in manufacturing and warehousing facilities to enhance process optimization and productivity.

Baraja

Series A in 2019
Baraja is a deep technology company specializing in advanced LiDAR solutions for autonomous vehicles. It has developed a unique platform called Spectrum-Scan™, which employs a novel approach to light detection and ranging by utilizing prisms instead of traditional moving parts and mirrors. This innovative method refracts light through optics connected to a wavelength-tunable laser, allowing for enhanced scanning capabilities. As a result, Baraja's technology offers superior range, precision, and reliability, even in challenging environments. This advancement enables manufacturers of self-driving cars to achieve instantaneous multi-angle scanning with high detail and adaptability, positioning Baraja as a leader in the autonomous vehicle technology sector.

Emesent

Seed Round in 2018
Emesent specializes in developing drone technology for data collection and analysis in challenging underground environments. Its flagship product, Hovermap, enables drones to fly and map in GPS-denied areas like mines, enhancing safety, efficiency, and operational insights.
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