Lewis & Clark Ventures

Lewis & Clark Ventures, established in 2015 and located in Saint Louis, Missouri, is a venture capital firm focused on investing in high-potential B2B software, fintech, and digital health companies. Founded by former operators, the firm aims to identify and support innovation and entrepreneurial talent in often overlooked regions. By partnering with entrepreneurs, Lewis & Clark Ventures seeks to assist these companies in their growth and development, ultimately guiding them toward greater scale and significance. As a Registered Investment Adviser, the firm is committed to fostering strong relationships with the businesses it finances, positioning itself as a trusted ally in their journey.

Scott Bernstein

Principal

Brian Hopcraft

Managing Director and Founder

Nick Nardacci

Senior Associate

Michael Rockhold

Principal

Michael Rockhold

Principal

Rohan Verma

Principal

Past deals in Missouri

Sailes

Series A in 2023
Saile is a company that leverages artificial intelligence to enhance sales efficiency for leaders and organizations. Its innovative technology, known as Sailebots, automates a wide range of prospecting tasks, significantly reducing the time spent on manual labor while increasing revenue opportunities. Sailebots are capable of managing the entire prospecting lifecycle, which includes finding contacts, scheduling meetings, data cleansing, and summarizing reports related to prospective companies. This patent-pending digital labor solution is currently operational in 29 countries and supports multiple languages, making it a versatile tool for global sales teams. Headquartered in Kansas City, Missouri, Saile employs a diverse workforce distributed across various locations worldwide.

NewLeaf Symbiotics

Series C in 2017
NewLeaf Symbiotics is an agriculture technology company based in Saint Louis, Missouri, that specializes in the research, development, and commercialization of beneficial symbiotic bacteria aimed at enhancing plant health and increasing crop yields. The company focuses on natural bacteria, particularly pink pigmented facultative methylotrophs, which are utilized in various agricultural products for row crops, vegetables, fruits, and flowers. Through laboratory, greenhouse, and field trials, NewLeaf Symbiotics aims to provide sustainable agricultural solutions that assist farmers in combating plant diseases and improving overall agricultural productivity. Founded in 2011 and originally known as TrophoMax, LLC, the company rebranded to its current name in 2012.

Adarza BioSystems

Series C in 2017
Adarza BioSystems is an early-stage medical diagnostics company based in St. Louis, Missouri, founded in 2008. The company specializes in developing a rapid and label-free biological assay platform that measures clinical and point-of-care samples. This innovative platform employs diagnostic arrayed imaging reflectometry (AIR) to enable the simultaneous detection of hundreds of analytes from a single drop of fluid, allowing healthcare professionals to conduct sophisticated tests with high sensitivity and specificity. By significantly reducing the time required for testing, Adarza BioSystems aims to enhance diagnostic capabilities in various healthcare settings.

Adarza BioSystems

Series B in 2016
Adarza BioSystems is an early-stage medical diagnostics company based in St. Louis, Missouri, founded in 2008. The company specializes in developing a rapid and label-free biological assay platform that measures clinical and point-of-care samples. This innovative platform employs diagnostic arrayed imaging reflectometry (AIR) to enable the simultaneous detection of hundreds of analytes from a single drop of fluid, allowing healthcare professionals to conduct sophisticated tests with high sensitivity and specificity. By significantly reducing the time required for testing, Adarza BioSystems aims to enhance diagnostic capabilities in various healthcare settings.
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