Legend Capital

Core Medical Technology is a technology enterprise mainly engaged in the research, production, development, and sales of implantable left ventricular assist devices, extracorporeal ventricular assist devices, percutaneous interventional ventricular assist devices, and equipment. The company was founded in 2016 and is based in Shenzhen, China.

Easy-Flow is committed to efficiently creating a complete set of solutions in the field of peripheral interventional devices.

TOPI Imaging Technology is a medical device firm providing OCT retinal diagnostic system and sweep optical biometer.

Chuangrui Spectrum specializes in the design and manufacture of time-resolved spectroscopy devices and equipment. Chuangrui Spectrum focuses mainly on research and development, as well as the manufacture and marketing of high-end scientific research equipment.

Ensurge Medical is a medical equipment developer, specializing in research, development, production, and sales of intelligent medical products like surgical energy instruments and ultrasonic scalpels.

DK Medtech is a medical technology company based in Suzhou, China, specializing in the development and production of balloon catheter medical devices. Founded in 2015, the company has positioned itself as a leader in the medical device industry, focusing on innovative solutions to address complex healthcare challenges. Through its commitment to excellence, DK Medtech aims to improve patient outcomes and enhance the quality of healthcare.

Dearer Medical is a medical device company based in China that specializes in the development, production, and sales of eye-related products, particularly contact lenses. The company is dedicated to research and development in this field, focusing on both practical and fashionable color contact lens options. By combining innovation with quality manufacturing, Dearer Medical aims to meet the diverse needs of customers seeking enhanced vision solutions.

Ligatech Bioscience, established in 2014 and headquartered in Qingpu, China, specializes in the design, development, production, and sales of medical devices for orthopedic and sports medicine. Its product portfolio includes molecular weight polyethylene suture and striped titanium plates, along with artificial ligaments and fixation systems. The company also offers technical advice and services to its users.

Jinqirui Biology is a biotechnology company that focuses on the research and development, manufacturing, production & sales of vitro diagnostics equipment and reagents.

Chuangrui Spectrum specializes in the design and manufacture of time-resolved spectroscopy devices and equipment. Chuangrui Spectrum focuses mainly on research and development, as well as the manufacture and marketing of high-end scientific research equipment.

Tripod Preclinical Research is a Contract Research Organization that specializes in preclinical research services tailored for the biopharmaceutical industry. The company offers a comprehensive range of services, including nonhuman primate disease models, pharmacological efficacy assessments, early drug evaluations, and GLP toxicology. Tripod is committed to supporting global pharmaceutical companies, research and development enterprises, and medical device manufacturers in the evaluation of new chemical entities, food additives, biologics, pesticides, veterinary drugs, and cosmetics. Additionally, the organization provides technology support in areas such as translational medicine, clinical trials, biological analysis, and the management of biological sample banks, ensuring that its clients have the necessary resources to advance their research and development efforts effectively.

Sifli Technologies specializes in the design and development of chips for embedded artificial intelligence and Internet of Things (IoT) applications. The company creates platforms that facilitate data collection and processing for IoT sensors, as well as inferential processing for edge artificial intelligence. Its products support a range of applications, including smart wearables, medical and health equipment, home automation, intelligent terminals, industrial instruments, and intelligent buildings. By focusing on these areas, Sifli Technologies aims to enhance the functionality and efficiency of connected devices across various industries.

Easy-Flow is committed to efficiently creating a complete set of solutions in the field of peripheral interventional devices.

VectorBuilder is an online platform specializing in the development and optimization of gene delivery solutions, catering to both basic research and clinical applications. The platform enables researchers to design and order custom gene delivery vectors with ease, effectively simplifying the traditionally complex processes involved in vector construction and production. VectorBuilder offers a comprehensive array of contract research organization (CRO) services, including scientific research vector customization and clinical vector preparation. Additionally, the company provides advanced capabilities in gene delivery technologies and AAV capsid engineering, supported by extensive inventories and state-of-the-art facilities that comply with Good Manufacturing Practices (GMP). By streamlining the process of vector cloning and offering personalized solutions, VectorBuilder supports advancements in life sciences and drug development.

Joymed Technology specializes in the research and development, registration, and manufacturing of medical devices, providing comprehensive solutions tailored for medical equipment businesses. The company focuses on delivering innovative and reliable technology while ensuring high-quality standards in its products. By offering services such as device design, risk management, marketing, and product verification and validation, Joymed Technology enables its clients to develop and launch safe and affordable medical products efficiently. The company aims to become a trusted partner for both domestic and international medical device firms, particularly assisting small and medium-sized enterprises in navigating the complexities of the medical product market. Through flexible collaboration and optimized design processes, Joymed Technology seeks to accelerate mutual growth with its customers.

ClinChoice, also known as Fountain Medical Development Ltd, is a contract research organization based in Beijing, China. The company specializes in providing comprehensive, ICH GCP compliant clinical research services to multinational clients in both China and the United States. Its offerings include consulting, project management, regulatory affairs, and clinical operations, as well as central laboratory services. ClinChoice also focuses on site management, biometrics, and designing clinical trials. Additional services encompass the collection, review, assessment, and reporting of adverse events and serious adverse events, along with data and safety monitoring board handling and signal detection services. Founded in 2006, ClinChoice has established itself as a key player in the clinical research sector.

Reliable Med is a medical device developer focused on creating and providing clinical mass spectrometry equipment for in vitro diagnostic (IVD) tests. The company addresses a significant need in the medical industry by offering high-end clinical mass spectrometry solutions and IVD detection kits. By enhancing diagnostic capabilities, Reliable Med aims to enable healthcare professionals to diagnose patients more efficiently and accurately.

Beijing Tianxing is a clinical solutions company for sports medicine for implants, arthroscopy devices, and sports medicine equipment.

ColorTech Bio researches and develops precision molecular diagnostic equipment. It offers medical devices to improve biotechnology services and solutions. ColorTech Bio was founded in 2018 and is based in Suzhou, China.

Sailner 3D Technology specializes in the development and sale of industrial-grade 3D printers, focusing on color and multi-material printing capabilities. The company's innovative WJP white ink filling technology enables voxel-level precision, allowing for the creation of detailed and customizable products. Sailner's 3D printing solutions find applications in various sectors, including digital medical education, surgical planning, and industrial design, as well as in the production of high-precision jewelry models. Through its commitment to research and development, Sailner aims to enhance additive manufacturing technology and provide tailored applications to meet diverse industrial needs.

ForQaly is a medical device company specializing in the development of minimally invasive ventricular assist devices aimed at treating heart failure. The company focuses on creating therapeutic solutions that enhance circulation for patients, ensuring affordability and ease of use for healthcare providers. By prioritizing small trauma and large auxiliary flow in its designs, ForQaly's products are intended to offer effective and accessible care for individuals suffering from heart-related conditions, ultimately improving patient outcomes and quality of life.

Dearer Medical is a medical device company based in China that specializes in the development, production, and sales of eye-related products, particularly contact lenses. The company is dedicated to research and development in this field, focusing on both practical and fashionable color contact lens options. By combining innovation with quality manufacturing, Dearer Medical aims to meet the diverse needs of customers seeking enhanced vision solutions.

Reliable Med is a medical device developer focused on creating and providing clinical mass spectrometry equipment for in vitro diagnostic (IVD) tests. The company addresses a significant need in the medical industry by offering high-end clinical mass spectrometry solutions and IVD detection kits. By enhancing diagnostic capabilities, Reliable Med aims to enable healthcare professionals to diagnose patients more efficiently and accurately.

Jinqirui Biology is a biotechnology company that focuses on the research and development, manufacturing, production & sales of vitro diagnostics equipment and reagents.

Kunya Medical is a provider of medical equipment management services, specializing in the maintenance, installation, and repair of hospital medical equipment. The company offers comprehensive outsourcing solutions that enhance the efficiency of medical equipment management within hospitals, thereby extending the lifecycle of critical clinical devices. Kunya Medical caters to both domestic and international brands of large and medium-sized medical equipment, delivering services such as technical maintenance, equipment relocation, installation, and debugging. Additionally, the company supplies a full range of spare parts and equipment management software, ensuring that hospitals can effectively manage their medical assets.

GensKey is a medical diagnostic service provider specializing in genetic testing for pathogen diagnosis. The company utilizes high-throughput sequencing technology combined with intelligent algorithm analysis to address challenges associated with traditional diagnostic methods, such as low detection rates, lengthy processes, and accuracy issues. By improving the timeliness and precision of pathogen diagnosis, GensKey enables patients suffering from severe infections to receive prompt and reliable diagnoses, thereby enhancing the potential for effective treatment and recovery.

Hemu (China) Biological Engineering is a Chinese blood vessel intervention medical equipment firm.

HEMO BIOENGINEERING develops and provides innovative interventional medical devices to patients.

JenaValve Technology, Inc. is a medical device company specializing in the design, development, and manufacturing of transcatheter aortic valve replacement (TAVR) systems for patients with severe aortic regurgitation and aortic stenosis. Founded in 2006 and headquartered in Irvine, California, with additional locations in Munich, Germany, and Leeds, United Kingdom, the company focuses on providing innovative solutions for high-risk patients who may not be suitable candidates for traditional surgical aortic valve replacement. The company's flagship product, the Trilogy™ Heart Valve System, received CE Mark approval in May 2021 and is notable for its dual-disease treatment capabilities. JenaValve's TAVR systems feature a porcine pericardial trileaflet valve mounted on a low-profile nitinol self-expanding frame, designed to engage with the native valve structures for optimal performance. The company has also received Breakthrough Device Designation from the U.S. Food and Drug Administration to facilitate the review of its pivotal trial for the Trilogy Heart Valve System in the United States.

GensKey is a medical diagnostic service provider specializing in genetic testing for pathogen diagnosis. The company utilizes high-throughput sequencing technology combined with intelligent algorithm analysis to address challenges associated with traditional diagnostic methods, such as low detection rates, lengthy processes, and accuracy issues. By improving the timeliness and precision of pathogen diagnosis, GensKey enables patients suffering from severe infections to receive prompt and reliable diagnoses, thereby enhancing the potential for effective treatment and recovery.

Nanovision Technology, based in the Zhongguancun Yongfeng high-tech industrial base, specializes in high-speed and high-precision radiology imaging solutions. With a significant research and development presence in Yonyou Industrial Park and a subsidiary in Chengdu, the company focuses on static computed tomography (CT), X-ray CMOS detectors, and X-ray imaging software. Notably, Nanovision developed China's first self-designed CMOS flat panel detector, known as the Merak series, which serves a diverse range of applications across medical, industrial, and security sectors. By providing advanced technological support both domestically and internationally, Nanovision aims to enhance imaging capabilities in various fields.

dMed Company Limited, also known as dMed Biopharmaceutical Co., Ltd., is a clinical contract research organization based in Shanghai, China. Established in 2016, dMed specializes in offering a comprehensive range of services to support the development of medicines and medical devices. Its offerings include consulting, clinical operations, biostatistics and programming, data management, pharmacovigilance, clinical science and medical affairs, quality assurance, and regulatory affairs and strategy. The company serves a diverse clientele, including biopharmaceutical and medical device companies, and aims to establish itself as a prominent international brand in the field of drug innovation services and solutions.

Guoke Hengtai (Beijing) Medical Technology Co., Ltd. is a Chinese company established in February 2013 and headquartered in the Yizhuang Economic and Technological Development Zone of Beijing. It operates under the umbrella of Oriental Science and Technology Holding Group Co., Ltd., which is connected to the State-owned Assets Supervision and Administration Commission of the Chinese Academy of Sciences. GKHT Medical Technology specializes in the distribution and direct sales of medical devices, offering a range of professional services, including warehousing logistics, distribution channel management, and hospital SPD operation management. Since its inception, the company has demonstrated significant growth, achieving a compound annual growth rate of over 50%, and it is currently pursuing an initial public offering.

Bondent Technology Co., Ltd., headquartered in Shanghai, China, specializes in supplying dental equipment and materials. It offers a comprehensive range of services, including technical training, operational and management consulting, decoration design, and financial solutions. Bondent's core business involves the design, development, manufacturing, and sales of oral medical equipment, creating a full ecosystem for the dental and oral health industry.

New Horizon Health is a biotechnology company based in Hangzhou, China, with an additional office in Beijing, specializing in the development of innovative technologies for early cancer detection and screening. Founded in 2015, the company primarily focuses on gastrointestinal cancers, offering products such as the ColoClear and Pupu Tube, which utilize fecal gene analysis (FIT-DNA) technology for colorectal cancer screening. These products enable users to conduct in-home tests, allowing for the early detection of colon cancer and precancerous lesions that may not be identified through traditional blood tests. New Horizon Health aims to reduce cancer morbidity and mortality rates by promoting accessible and efficient health services, leveraging big data and artificial intelligence in its screening technologies. The company's commitment to early cancer screening reflects its mission to enhance public health by facilitating widespread access to vital diagnostic tools.

GensKey is a medical diagnostic service provider specializing in genetic testing for pathogen diagnosis. The company utilizes high-throughput sequencing technology combined with intelligent algorithm analysis to address challenges associated with traditional diagnostic methods, such as low detection rates, lengthy processes, and accuracy issues. By improving the timeliness and precision of pathogen diagnosis, GensKey enables patients suffering from severe infections to receive prompt and reliable diagnoses, thereby enhancing the potential for effective treatment and recovery.

Jinqirui Biology is a biotechnology company that focuses on the research and development, manufacturing, production & sales of vitro diagnostics equipment and reagents.

Aohua is a global provider of endoscopy devices and solutions, focused on advancing endoscope technology and enhancing diagnostic and treatment capabilities in endoscopy. Founded in 1994 and based in Shanghai, China, the company specializes in the research, development, production, and sales of electronic endoscope equipment, along with associated diagnostic and surgical consumables. Aohua aims to lead innovation in endoscopic technology, contributing to the overall progress of medical endoscopy practices.

Urotronic Inc., established in 2014 and headquartered in Plymouth, Minnesota, specializes in developing and manufacturing medical devices for urological applications. The company's primary product is Optilume, a Drug Coated Balloon (DCB) catheter designed to treat urethral strictures in men by dilating the blocked area and delivering a drug that prevents scar tissue formation. This minimally invasive procedure reduces patient discomfort and recovery time compared to traditional surgical methods. Urotronic serves both urologists and patients, aiming to improve treatment outcomes for urinary tract conditions.

Chemclin Biotech is a Chinese technical service provider specializing in in-vitro diagnostic instruments and auxiliary reagents for clinical diagnosis. The company develops, produces, and sells clinical immunochemiluminescence diagnostic testing reagents and instruments. Its service offerings encompass clinical inspection instruments, various types of auxiliary reagents, technical support, management and certification, as well as the operation of independent medical laboratories. Chemclin is committed to introducing advanced diagnostic products and services to the Chinese market, thereby enhancing the capabilities of clinical diagnostics in the region.

Puyi Biotechnology is a company focused on the high-value medical device market, with a specialization in material science and drug delivery technology. It has established a distinctive presence in several medical fields, including ear, nose, and throat (ENT) care, reproductive health, and medical aesthetics. The company develops minimally-invasive implanted medical devices designed for healthcare professionals, particularly emphasizing degradable, drug-releasing sinus stents that enhance patient outcomes following surgery. Through its innovative approach, Puyi Biotechnology aims to improve treatment efficacy and patient recovery in various medical applications.

Yosemite Clinic is a comprehensive medical facility located in Central Pudong, Shanghai, offering a wide range of walk-in medical services. The clinic specializes in various fields, including family and internal medicine, surgery, orthopedics, dermatology, medical cosmetology, dentistry, gynecology, pediatrics, ophthalmology, and rehabilitation medicine. Equipped with advanced technology, Yosemite Clinic features state-of-the-art facilities such as CT, X-ray, ultrasound, and operating rooms, ensuring high-quality care. The clinic's diverse team of medical professionals, hailing from both China and around the globe, allows it to provide services in multiple languages, including English, Japanese, Malay, Mandarin Chinese, and Cantonese. By combining a multidisciplinary approach with modern medical practices, Yosemite Clinic aims to meet the diverse healthcare needs of its patients effectively.

Kunya Medical is a provider of medical equipment management services, specializing in the maintenance, installation, and repair of hospital medical equipment. The company offers comprehensive outsourcing solutions that enhance the efficiency of medical equipment management within hospitals, thereby extending the lifecycle of critical clinical devices. Kunya Medical caters to both domestic and international brands of large and medium-sized medical equipment, delivering services such as technical maintenance, equipment relocation, installation, and debugging. Additionally, the company supplies a full range of spare parts and equipment management software, ensuring that hospitals can effectively manage their medical assets.

ImmunoChina Pharmaceuticals manufactures medical products. The Company produces cell injections, cell therapy drugs, and other products. ImmunoChina Pharmaceuticals also provides medical technology development, medical research, medical trial development, and other services.

New Horizon Health is a biotechnology company based in Hangzhou, China, with an additional office in Beijing, specializing in the development of innovative technologies for early cancer detection and screening. Founded in 2015, the company primarily focuses on gastrointestinal cancers, offering products such as the ColoClear and Pupu Tube, which utilize fecal gene analysis (FIT-DNA) technology for colorectal cancer screening. These products enable users to conduct in-home tests, allowing for the early detection of colon cancer and precancerous lesions that may not be identified through traditional blood tests. New Horizon Health aims to reduce cancer morbidity and mortality rates by promoting accessible and efficient health services, leveraging big data and artificial intelligence in its screening technologies. The company's commitment to early cancer screening reflects its mission to enhance public health by facilitating widespread access to vital diagnostic tools.

Indi Molecular is a life sciences company based in Culver City, California, developing a fully synthetic class of diagnostic and therapeutic agents with antibody-like properties, known as protein-catalyzed capture agents (PCCs). PCCs are designed to replace traditional antibodies in in vivo imaging, therapeutics, and diagnostics, using a shared chelation chemistry platform that enables tailoring for therapeutic or PET imaging radionuclides. Produced via click chemistry, PCCs offer high selectivity, strong binding affinity, low molecular weight, and a fully synthetic composition compared with monoclonal antibodies. The company originated as a spinout from Integrated Diagnostics in 2013.

PhiSkin is a skin and laser clinic based in China that specializes in aesthetic medicine. The company offers a range of services including aesthetic product injections, such as Botox and hyaluronic acid, laser treatments, double eyelid surgery, and various non-surgical beauty procedures. PhiSkin aims to provide customers with a thorough understanding of their skin conditions while delivering tailored skincare solutions to meet individual needs.

Shanghai Neuromedical Center is a specialized neurology clinic dedicated to advancing functional neurosurgery and providing comprehensive care in areas such as neurosurgery, neurology, neurorehabilitation, neuropsychology, and emergency critical care medicine. The center focuses on delivering expert treatment for conditions such as brain tumors and epilepsy, ensuring that patients receive high-quality, specialized care. By integrating clinical practice with scientific research and education, Shanghai Neuromedical Center aims to enhance patient outcomes and contribute to the evolution of neurosurgical techniques and methodologies.

Hisky Medical is a company based in Beijing, China, established in 2010, that specializes in the development, manufacturing, and marketing of medical equipment aimed at non-invasive liver diagnosis. The firm focuses on innovative technologies for disease diagnosis and has developed a product called FibroTouch, which is designed to facilitate the assessment of liver conditions without the need for invasive procedures. Through its advancements in medical technology, Hisky Medical aims to improve diagnostic accuracy and patient comfort in the evaluation of liver health.

DBSec is a reputable supplier of data security products, services, and solutions. They provide database encryption systems, database audit systems, cloud data security products, and holistic data security solutions. They serve the government, finance, social security, energy, military, operator, education, medical, and other industries.

New Horizon Health is a biotechnology company based in Hangzhou, China, with an additional office in Beijing, specializing in the development of innovative technologies for early cancer detection and screening. Founded in 2015, the company primarily focuses on gastrointestinal cancers, offering products such as the ColoClear and Pupu Tube, which utilize fecal gene analysis (FIT-DNA) technology for colorectal cancer screening. These products enable users to conduct in-home tests, allowing for the early detection of colon cancer and precancerous lesions that may not be identified through traditional blood tests. New Horizon Health aims to reduce cancer morbidity and mortality rates by promoting accessible and efficient health services, leveraging big data and artificial intelligence in its screening technologies. The company's commitment to early cancer screening reflects its mission to enhance public health by facilitating widespread access to vital diagnostic tools.

Bionano Genomics, Inc. is a biotechnology company focused on genome mapping and analysis. It develops and markets the Saphyr system, an advanced platform designed for ultra-sensitive and specific detection of structural variations in DNA, such as insertions, deletions, and translocations, which are often linked to genetic disorders and diseases, including cancer. The Saphyr system employs optical genome mapping technology, allowing for direct visualization and analysis of long DNA molecules without relying on sequencing. This capability provides researchers and clinicians with critical insights into the structural variations within genomes, enhancing the understanding of disease mechanisms and supporting the development of personalized treatment strategies. Bionano Genomics also offers essential reagents and data solutions, including Bionano prep kits, labeling kits, and software tools for comprehensive experiment management. Its products are primarily sold to academic and governmental research laboratories, as well as pharmaceutical, biotechnology, and contract research organizations across multiple regions, including North America, Europe, and Asia. Founded in 2003 and headquartered in San Diego, California, the company was previously known as BioNano Genomics, Inc. until its name change in July 2018.

Aohua is a global provider of endoscopy devices and solutions, focused on advancing endoscope technology and enhancing diagnostic and treatment capabilities in endoscopy. Founded in 1994 and based in Shanghai, China, the company specializes in the research, development, production, and sales of electronic endoscope equipment, along with associated diagnostic and surgical consumables. Aohua aims to lead innovation in endoscopic technology, contributing to the overall progress of medical endoscopy practices.

Audoline is a hearing healthcare platform. They provide hearing medical services. They also provide a cochlear implant, a hearing aid, bone anchored hearing aids, and hearing accessories.

JenaValve Technology, Inc. is a medical device company specializing in the design, development, and manufacturing of transcatheter aortic valve replacement (TAVR) systems for patients with severe aortic regurgitation and aortic stenosis. Founded in 2006 and headquartered in Irvine, California, with additional locations in Munich, Germany, and Leeds, United Kingdom, the company focuses on providing innovative solutions for high-risk patients who may not be suitable candidates for traditional surgical aortic valve replacement. The company's flagship product, the Trilogy™ Heart Valve System, received CE Mark approval in May 2021 and is notable for its dual-disease treatment capabilities. JenaValve's TAVR systems feature a porcine pericardial trileaflet valve mounted on a low-profile nitinol self-expanding frame, designed to engage with the native valve structures for optimal performance. The company has also received Breakthrough Device Designation from the U.S. Food and Drug Administration to facilitate the review of its pivotal trial for the Trilogy Heart Valve System in the United States.

MNCHIP is a developer and supplier of a comprehensive range of in vitro diagnostic (IVD) equipment aimed at enhancing clinical decision-making and treatment pathways. The company focuses on delivering high-quality medical devices at affordable prices, thereby ensuring accessibility for patients across different income levels. Among its current offerings are a chemistry analyzer and a PCR analyzer that utilize microfluidics technology, which improve the efficiency of IVD tests. Additionally, MNCHIP is preparing to launch an immunoassay analyzer and a hematology analyzer, further expanding its product line. By consistently bringing innovative solutions to market, MNCHIP plays a significant role in reducing healthcare spending while supporting healthcare professionals in their diagnostic efforts.

Bionano Genomics, Inc. is a biotechnology company focused on genome mapping and analysis. It develops and markets the Saphyr system, an advanced platform designed for ultra-sensitive and specific detection of structural variations in DNA, such as insertions, deletions, and translocations, which are often linked to genetic disorders and diseases, including cancer. The Saphyr system employs optical genome mapping technology, allowing for direct visualization and analysis of long DNA molecules without relying on sequencing. This capability provides researchers and clinicians with critical insights into the structural variations within genomes, enhancing the understanding of disease mechanisms and supporting the development of personalized treatment strategies. Bionano Genomics also offers essential reagents and data solutions, including Bionano prep kits, labeling kits, and software tools for comprehensive experiment management. Its products are primarily sold to academic and governmental research laboratories, as well as pharmaceutical, biotechnology, and contract research organizations across multiple regions, including North America, Europe, and Asia. Founded in 2003 and headquartered in San Diego, California, the company was previously known as BioNano Genomics, Inc. until its name change in July 2018.

LenoMed Medical is a manufacturer of medical devices focused on improving diabetes management. With over 15 years of research and development experience in infusion technology, the company specializes in creating innovative products such as the InnoTech insulin pump, drug infusion pumps, and related disposables. LenoMed is dedicated to enhancing diabetes care through the integration of continuous glucose monitoring technology with their insulin pumps, aiming to provide patients with better treatment options and monitoring capabilities. Their commitment to advancing diabetes management is reflected in their comprehensive diabetes care management system.

JenaValve Technology, Inc. is a medical device company specializing in the design, development, and manufacturing of transcatheter aortic valve replacement (TAVR) systems for patients with severe aortic regurgitation and aortic stenosis. Founded in 2006 and headquartered in Irvine, California, with additional locations in Munich, Germany, and Leeds, United Kingdom, the company focuses on providing innovative solutions for high-risk patients who may not be suitable candidates for traditional surgical aortic valve replacement. The company's flagship product, the Trilogy™ Heart Valve System, received CE Mark approval in May 2021 and is notable for its dual-disease treatment capabilities. JenaValve's TAVR systems feature a porcine pericardial trileaflet valve mounted on a low-profile nitinol self-expanding frame, designed to engage with the native valve structures for optimal performance. The company has also received Breakthrough Device Designation from the U.S. Food and Drug Administration to facilitate the review of its pivotal trial for the Trilogy Heart Valve System in the United States.

Aohua is a global provider of endoscopy devices and solutions, focused on advancing endoscope technology and enhancing diagnostic and treatment capabilities in endoscopy. Founded in 1994 and based in Shanghai, China, the company specializes in the research, development, production, and sales of electronic endoscope equipment, along with associated diagnostic and surgical consumables. Aohua aims to lead innovation in endoscopic technology, contributing to the overall progress of medical endoscopy practices.

Reach Surgical is a manufacturer of surgical instruments and medical equipment that integrates research and development, production, and sales. Founded in 2005, the company is based in China and operates three research and development centers located in Cincinnati, USA, and in Beijing and Shanghai. Reach Surgical specializes in producing high-end surgical devices, including open series staplers and endoscopic staplers designed for thoracic and general surgery. Its products have received approvals from the US FDA and the EU CE, ensuring compliance with international standards. The company is dedicated to providing advanced and minimally invasive surgical solutions to enhance the efficiency of clinical surgeries worldwide.

JenaValve Technology, Inc. is a medical device company specializing in the design, development, and manufacturing of transcatheter aortic valve replacement (TAVR) systems for patients with severe aortic regurgitation and aortic stenosis. Founded in 2006 and headquartered in Irvine, California, with additional locations in Munich, Germany, and Leeds, United Kingdom, the company focuses on providing innovative solutions for high-risk patients who may not be suitable candidates for traditional surgical aortic valve replacement. The company's flagship product, the Trilogy™ Heart Valve System, received CE Mark approval in May 2021 and is notable for its dual-disease treatment capabilities. JenaValve's TAVR systems feature a porcine pericardial trileaflet valve mounted on a low-profile nitinol self-expanding frame, designed to engage with the native valve structures for optimal performance. The company has also received Breakthrough Device Designation from the U.S. Food and Drug Administration to facilitate the review of its pivotal trial for the Trilogy Heart Valve System in the United States.

Bonovo Orthopedics, Inc. is a provider of orthopedic implants and related products tailored for the Chinese healthcare market. Established in 2005 and headquartered in Scottsdale, Arizona, the company specializes in a wide range of products, including artificial discs, plates, and fixation systems for spinal treatments, as well as hip and knee joint systems and bone void fillers. Bonovo also offers minimally invasive surgical solutions, such as kyphoplasty systems for vertebral fracture management, along with a variety of surgical instruments and devices. With over 15 years of experience in manufacturing and distributing orthopedic products, Bonovo Orthopedics has built strong relationships with leading clinicians and hospitals, positioning itself as a key player in the Chinese orthopedic landscape. The company operates manufacturing facilities in Beijing and Shanghai, further supporting its commitment to providing advanced healthcare solutions.