Asynt Solutions
Seed Round in 2024
Founded in 2021, Asynt Solutions specializes in innovative safety solutions for transportation infrastructure and construction. The company manufactures lightweight, durable composite traffic barrier systems designed to absorb more energy during impact compared to traditional concrete barriers. These systems prioritize safety while enabling faster installation, removal, and reduced maintenance costs.
NeverEnding
Pre Seed Round in 2022
NeverEnding is a creative platform founded in 2020, headquartered in Cleveland, Ohio. It empowers creators and teams to bring their stories and imagination to life through animations and social content. The platform offers intuitive tools for designing characters for tabletop gaming, avatars for streaming, webcomics, and animated videos.
Axuall provides a digital platform for verifying identities, credentials, and authenticity across various sectors. It specializes in healthcare workforce intelligence, enabling healthcare systems, staffing firms, and telehealth providers to streamline onboarding processes and gain valuable data insights for network planning and analytics.
Checkpoint Surgical
Venture Round in 2021
Checkpoint Surgical Inc., established in 2009 and headquartered in Cleveland, Ohio, specializes in manufacturing neuro devices for surgeons. Their primary products are CHECKPOINT 9094 and CHECKPOINT 9394, both designed to locate, identify, and evaluate motor nerve tissue and muscle function during complex surgical procedures. These devices cater to various applications such as head and neck surgeries, hand and extremities procedures, targeted muscle re-innervation, orthopedic oncology and trauma, and plastic reconstruction. The company sells its products through a network of distributors in the United States, aiming to enhance patient outcomes by providing surgeons with precise nerve stimulation and monitoring equipment.
S4 Medical
Series A in 2021
Founded in 2017, S4 Medical specializes in developing medical devices for cardiac procedures. Its flagship product is a device designed to protect the esophagus during catheter ablation treatments for atrial fibrillation.
ReadySet Surgical
Series A in 2020
ReadySet Surgical LLC is a company based in Cincinnati, Ohio, that specializes in cloud-based software solutions for managing surgical vendor inventory. The platform enhances coordination and communication among surgical teams, sterilization departments, and medical device vendors, ensuring that every procedure is equipped with the correct contracted inventory and documentation. ReadySet Surgical also offers RS Analyze, a tool for hospitals to evaluate vendor performance and detect off-contract implant purchases through real-time data analytics, allowing for timely corrective actions. The company focuses on providing a user-friendly experience and seamless installation for hospital staff and vendor representatives. Established in 2014, ReadySet Surgical aims to improve the efficiency and transparency of the surgical supply chain, ultimately reducing delays and errors in surgical procedures.
S4 Medical
Venture Round in 2020
Founded in 2017, S4 Medical specializes in developing medical devices for cardiac procedures. Its flagship product is a device designed to protect the esophagus during catheter ablation treatments for atrial fibrillation.
Able (formerly EmployStream)
Series B in 2020
EmployStream is a hiring workflow automation software platform for staffing companies and other high-volume employers. It also creates high-quality, user-friendly for high-volume employers that automates the hiring and onboarding process for employers. The platform eliminates costly mistakes and delays allowing companies to hire up to 90% faster and at half the cost.
The company provides an online hiring platform which offers different features such as paper onboarding, real-time alerting, online application, background checks, applicant pre & interview screening, and verification.
EmployStream was founded in 2014 and is headquartered in Cleveland Ohio, USA.
MedPilot
Seed Round in 2019
MedPilot Inc. is a Cleveland-based company that offers an AI-driven patient relationship management platform, established in 2014. The company specializes in addressing administrative and billing challenges within the healthcare sector. MedPilot provides a payment platform that simplifies the verification process for patients, clearly explaining their financial obligations. Additionally, it enhances the patient experience through post-payment surveys that gather valuable feedback for healthcare providers. The platform includes a network of patient navigators who assist in managing medical payments, offering billing discounts and customizable payment plans. By focusing on advocacy services, MedPilot aims to resolve payment issues and optimize the overall patient experience in the healthcare community.
Vitalxchange
Pre Seed Round in 2019
Vitalxchange operates a holistic virtual platform for families of children with autism and developmental disabilities. The platform combines human expertise with a proprietary expert system to support parenting and child development across areas such as behavioral, learning, and overall well-being. Families are matched with a team of VitalGuides who provide ongoing support, identify problems early, and facilitate connections with clinical or educational providers. The service offers a subscription model that can be purchased directly or accessed through employer benefits programs, and emphasizes fast, actionable information from peer experts and professionals on topics ranging from picky eating to disability planning. The company aims to empower parents to show up confidently and access timely guidance for their child’s needs.
Able (formerly EmployStream)
Series A in 2019
EmployStream is a hiring workflow automation software platform for staffing companies and other high-volume employers. It also creates high-quality, user-friendly for high-volume employers that automates the hiring and onboarding process for employers. The platform eliminates costly mistakes and delays allowing companies to hire up to 90% faster and at half the cost.
The company provides an online hiring platform which offers different features such as paper onboarding, real-time alerting, online application, background checks, applicant pre & interview screening, and verification.
EmployStream was founded in 2014 and is headquartered in Cleveland Ohio, USA.
enosiX, Inc. is a technology company that specializes in real-time integration solutions connecting Salesforce with SAP systems. Founded in 2014 and based in Cincinnati, Ohio, enosiX develops a range of products that facilitate seamless data exchange and enhance business processes. Key offerings include Enosix Connect, which integrates SAP/ERP systems with cloud applications, and Enosix Engage, which enables direct access to SAP ERP data within Salesforce without the need for middleware. The company's platform empowers Salesforce users with essential information such as customer data, inventory, and order management, all in real-time. This integration allows organizations to improve productivity, increase sales effectiveness, and enhance customer engagement. Additionally, enosiX provides mobile solutions for various business functions, ensuring that critical SAP data is accessible to an increasingly mobile workforce. With a focus on reducing integration time from months to days, enosiX enhances operational efficiency and drives better business outcomes.
Mezu
Venture Round in 2018
Mezu, Inc. is a banking technology company based in Cleveland Heights, Ohio, incorporated in 2017. It operates a mobile payment application that enables users to send and receive money privately and securely, without the need to share personal information. The app facilitates cash-like transactions, allowing users to pay, tip, earn, and donate without incurring fees. Available on both iOS and Android platforms in the United States, Mezu prioritizes user privacy, emphasizing that financial activities should remain confidential.
S4 Medical
Seed Round in 2018
Founded in 2017, S4 Medical specializes in developing medical devices for cardiac procedures. Its flagship product is a device designed to protect the esophagus during catheter ablation treatments for atrial fibrillation.
Wisr Inc. operates an online platform that enhances alumni engagement and student outcomes for higher education institutions. Founded in 2016 and based in Rocky River, Ohio, Wisr facilitates digital coaching by connecting current students with alumni, allowing for personalized guidance in career development. Its platform supports career services and alumni relations offices by automating the matching process, scheduling, and follow-up communications. This approach enables students to build a personal board of advisors, fostering meaningful connections that can positively influence their career paths.
Komae, Inc. is an application-based platform founded in 2015 and headquartered in Akron, Ohio, that facilitates the exchange of babysitting services among parents within their personal networks. The app enables users to create trusted social connections with friends and family to trade babysitting hours using a point system. With over 12,500 accounts created, Komae allows parents to manage child care more flexibly by scheduling playdates and coordinating care without financial transactions. The company operates on the principle that community support is vital for parenting, as reflected in its name, which means "village" in Greek. Komae aims to expand its services beyond child care to include pet sitting, carpooling, and elder care, fostering a broader communal sharing platform.
Able (formerly EmployStream)
Series A in 2017
EmployStream is a hiring workflow automation software platform for staffing companies and other high-volume employers. It also creates high-quality, user-friendly for high-volume employers that automates the hiring and onboarding process for employers. The platform eliminates costly mistakes and delays allowing companies to hire up to 90% faster and at half the cost.
The company provides an online hiring platform which offers different features such as paper onboarding, real-time alerting, online application, background checks, applicant pre & interview screening, and verification.
EmployStream was founded in 2014 and is headquartered in Cleveland Ohio, USA.
Able (formerly EmployStream)
Seed Round in 2017
EmployStream is a hiring workflow automation software platform for staffing companies and other high-volume employers. It also creates high-quality, user-friendly for high-volume employers that automates the hiring and onboarding process for employers. The platform eliminates costly mistakes and delays allowing companies to hire up to 90% faster and at half the cost.
The company provides an online hiring platform which offers different features such as paper onboarding, real-time alerting, online application, background checks, applicant pre & interview screening, and verification.
EmployStream was founded in 2014 and is headquartered in Cleveland Ohio, USA.
Neuros Medical
Series A in 2017
Neuros Medical, Inc. is a neuromodulation company dedicated to developing innovative therapies to address unmet medical needs for patients globally. Founded in 2008 and headquartered in Willoughby Hills, Ohio, the company specializes in its proprietary platform technology known as Electrical Nerve Block. This technology is designed to eliminate chronic pain across various conditions, including neuroma/residual limb pain, chronic post-surgical pain, and chronic migraine. The Neuros Altius System, one of its key products, includes an implantable generator with an integrated rechargeable battery, a cuff electrode, and external devices, further demonstrating the company's commitment to advancing pain management solutions.
Wisr Inc. operates an online platform that enhances alumni engagement and student outcomes for higher education institutions. Founded in 2016 and based in Rocky River, Ohio, Wisr facilitates digital coaching by connecting current students with alumni, allowing for personalized guidance in career development. Its platform supports career services and alumni relations offices by automating the matching process, scheduling, and follow-up communications. This approach enables students to build a personal board of advisors, fostering meaningful connections that can positively influence their career paths.
Monarch Teaching Technologies
Venture Round in 2017
Monarch Teaching Technologies, Inc. specializes in developing technology-enhanced solutions aimed at supporting educators, clinicians, and parents in the engagement and education of individuals with autism and other communication disorders. The company's flagship product, VizZle, is a web-based educational software that allows educators to create visually-supported curricula tailored to the needs of visual learners. This tool includes access to a peer-reviewed shared library of pre-made lessons as well as the ability to customize lessons using flexible templates, images, audio, and video clips. Additionally, Monarch Teaching Technologies provides training and help desk support to ensure effective use of its resources. Founded in 2005 and based in Shaker Heights, Ohio, the company was previously known as Ladybug, Inc.
StreamLink Software
Venture Round in 2016
StreamLink Software-is a Software-as-a-Service company that develops grant management software for nonprofits and the public sector. Ther grants management solution, AmpliFund, is designed for managing every stage of the grant lifecycle and is at the forefront of automating grant compliance and data standardization in the public sector.
It was founded in 2008 and is headquartered in Cleveland, Ohio.
ExpenseBot
Seed Round in 2016
ExpenseBot Inc. is a developer of an expense management platform that simplifies the process of business expense reporting. Founded in 2013 and headquartered in Shaker Heights, Ohio, the company offers a dashboard that allows users to create, approve, and reimburse expense reports efficiently. The platform leverages artificial intelligence, predictive analytics, and machine learning to automate the expense reporting process, pulling data from various sources such as calendar apps, emails, credit card transactions, and GPS. By analyzing expense data, ExpenseBot identifies reimbursable items and automatically generates expense reports when certain thresholds are met. This integration helps clients save time and reduces the challenges associated with organizing and submitting expenses.
Milo Biotechnology
Venture Round in 2016
Founded in 2011, Milo Biotechnology develops therapies aimed at increasing muscle strength and preventing muscle atrophy. Its primary focus is on an early-stage follistatin program, exclusively licensed from Nationwide Children's Hospital, designed to enhance muscle size and strength for patients with neuromuscular diseases.
StreamLink Software
Venture Round in 2016
StreamLink Software-is a Software-as-a-Service company that develops grant management software for nonprofits and the public sector. Ther grants management solution, AmpliFund, is designed for managing every stage of the grant lifecycle and is at the forefront of automating grant compliance and data standardization in the public sector.
It was founded in 2008 and is headquartered in Cleveland, Ohio.
Checkpoint Surgical
Series C in 2015
Checkpoint Surgical Inc., established in 2009 and headquartered in Cleveland, Ohio, specializes in manufacturing neuro devices for surgeons. Their primary products are CHECKPOINT 9094 and CHECKPOINT 9394, both designed to locate, identify, and evaluate motor nerve tissue and muscle function during complex surgical procedures. These devices cater to various applications such as head and neck surgeries, hand and extremities procedures, targeted muscle re-innervation, orthopedic oncology and trauma, and plastic reconstruction. The company sells its products through a network of distributors in the United States, aiming to enhance patient outcomes by providing surgeons with precise nerve stimulation and monitoring equipment.
Zuga Medical
Seed Round in 2013
Zuga Medical designs, manufactures, and markets innovative dental implant systems. Its patent-pending system enables dental professionals to reduce chair time, eliminate outsourced patient and laboratory services, allowing general dentists to perform complete patient services with fewer visits.
Intellirod Spine
Seed Round in 2013
Intellirod Spine, Inc. is a biomedical company based in Akron, Ohio, focused on the development and commercialization of innovative solutions for spinal surgery. The company's flagship product, the IntelliRod system, is a wireless implantable microelectronic sensor that attaches to spinal fusion implants. This sensor measures the load on the rod, providing surgeons with real-time data to assess the progress of spinal fusion over time. By offering objective insights into rod strain, the IntelliRod system helps spine surgeons evaluate the success of procedures, potentially reducing the need for unnecessary post-operative CT scans and exploratory surgeries. This technology not only aims to improve surgical outcomes but also facilitates quicker patient recovery and return to work after surgery. Intellirod Spine was previously known as OrthoData and was incorporated in 2003.
Casentric
Convertible Note in 2013
Casentric, LLC is a software company based in Shaker Heights, Ohio, founded in 2009. It specializes in developing CaseXpert, a cloud-based claims software designed for the property and casualty insurance sector. CaseXpert facilitates the evaluation and resolution of third-party personal injury and property damage claims, enabling claims handlers to assess liability and damages more accurately and efficiently. The application comprises four key components that streamline the claims process, including tools for evaluating comparative fault, assessing damages, generating reports, and providing negotiation guidance. By offering an intuitive interface, CaseXpert enhances the expertise of claims adjusters, reduces variability in claim outcomes, and helps organizations control expenses associated with claims. The software stands out in a market where many companies still rely on manual processes, contributing to inefficiencies and rising costs. Casentric's innovative approach addresses the industry's challenges, such as a shortage of experienced claims handlers and the need for improved training and evaluation methods, thereby positioning itself as a valuable solution for insurance companies looking to optimize their claims handling processes.
Guided Interventions
Seed Round in 2013
Guided Interventions is a Cleveland-based medical device startup led by CEO Dr. Matthew Pollman. The company specializes in the development of innovative wire-based medical devices, particularly a fractional flow reserve (FFR) guidewire aimed at enhancing coronary catheterization procedures. This guidewire is engineered to improve maneuverability and handling, allowing healthcare professionals to obtain accurate FFR measurements effectively. By focusing on maximizing efficacy while minimizing risks and costs, Guided Interventions seeks to reduce the reliance on stents for opening blocked arteries and to alleviate the painful and potentially dangerous side effects associated with heart surgery. Ultimately, the company aims to empower doctors to better assess the physiological impact of coronary artery blockages, thereby improving patient outcomes.
MedCity News
Seed Round in 2012
MedCity News creates content for people who care about health care.
It is a solution for media companies and organizations that need content, stakeholders who need actionable information about the medical industry, and advertisers who want to speak to this valuable niche audience.
Founded by veteran journalists with both health care reporting and online editorial experience, MedCity News is poised to build an innovative new-media enterprise capable of taking advantage of these converging forces while building a profitable national business and brand.
It operates the MedCity News Service, a type of niche wire service focused on the innovation economies in major "medical cities" and states (it has offices in Minnesota and Ohio, but also covers dealflow in the Midwest and Pittsburgh). It also operates MedCityNews.com and a custom content service that creates made-to-order content for anyone that wants it.
Its news content is syndicated throughthe Ohio News Network, Akron Beacon Journal, The Kindle, WKYC, the Boston online journal MassDevice and the Zemanta blog aggregator, among others.
Enforcer eCoaching
Seed Round in 2012
Enforcer eCoaching, Inc. is an email-based health coaching company based in Lyndhurst, Ohio, that specializes in delivering personalized wellness programs aimed at improving health outcomes, particularly for weight loss and diabetes management. Established in 2010, the company provides interactive and tailored health coaching services that focus on fostering enduring behavioral changes and enhancing the quality of life for its participants. By offering daily personalized advice and guidance, Enforcer eCoaching enables clients to adopt effective health-improvement strategies, including tobacco cessation and weight management, through a structured approach to wellness. The company collaborates with health systems and healthcare plans to reach a broader audience in its mission to promote healthier lifestyles.
Neuros Medical
Series B in 2012
Neuros Medical, Inc. is a neuromodulation company dedicated to developing innovative therapies to address unmet medical needs for patients globally. Founded in 2008 and headquartered in Willoughby Hills, Ohio, the company specializes in its proprietary platform technology known as Electrical Nerve Block. This technology is designed to eliminate chronic pain across various conditions, including neuroma/residual limb pain, chronic post-surgical pain, and chronic migraine. The Neuros Altius System, one of its key products, includes an implantable generator with an integrated rechargeable battery, a cuff electrode, and external devices, further demonstrating the company's commitment to advancing pain management solutions.
GenomOncology
Seed Round in 2012
GenomOncology is a Cleveland, Ohio based healthcare technology company focused on precision medicine. It translates next generation sequencing data into actionable information for clinicians and researchers. The company offers GO Clinical Workbench, a decision support tool that converts raw sequencing data into patient-specific molecular reports; GenomAnalytics, a research platform for rapid, near real-time genome analysis and data mining for new discoveries; and igniteIQ, a tool that extracts clinically relevant data from scanned or digital reports and converts it into discrete data elements. It supports assay validation, integrates with laboratory information systems and electronic medical records, and provides custom feature development services. GenomOncology serves clinical and research settings, enabling molecular tumor profiling, clinical decision support, and data-driven insights for cancer precision medicine. Founded in 2012 and based in Cleveland, Ohio.
Intelligent Mobile Support
Series A in 2012
Intelligent Mobile Support, Inc. is a technology company based in Solon, Ohio, founded in 2009. It specializes in developing a mobile cloud-computing platform aimed at enhancing the productivity and profitability of field sales and service teams, particularly within the HVAC industry. The company's product suite includes Sales Builder Pro, which automates the point-of-sale experience for clients, and Axon, an app that provides mobile access to essential parts information and technical support. Additionally, HVAC Proposal Builder Pro allows users to create professional proposals that facilitate immediate customer commitments. Intelligent Mobile Support serves a range of partners in the HVAC sector, including original equipment manufacturers, distributors, contractors, as well as providers in other home services such as plumbing and electrical work. The company's innovative solutions are designed to support sales representatives and technicians in the field, ultimately improving sales efficiency and closing rates.
Milo Biotechnology
Pre Seed Round in 2012
Founded in 2011, Milo Biotechnology develops therapies aimed at increasing muscle strength and preventing muscle atrophy. Its primary focus is on an early-stage follistatin program, exclusively licensed from Nationwide Children's Hospital, designed to enhance muscle size and strength for patients with neuromuscular diseases.
Intelligent Mobile Support
Seed Round in 2011
Intelligent Mobile Support, Inc. is a technology company based in Solon, Ohio, founded in 2009. It specializes in developing a mobile cloud-computing platform aimed at enhancing the productivity and profitability of field sales and service teams, particularly within the HVAC industry. The company's product suite includes Sales Builder Pro, which automates the point-of-sale experience for clients, and Axon, an app that provides mobile access to essential parts information and technical support. Additionally, HVAC Proposal Builder Pro allows users to create professional proposals that facilitate immediate customer commitments. Intelligent Mobile Support serves a range of partners in the HVAC sector, including original equipment manufacturers, distributors, contractors, as well as providers in other home services such as plumbing and electrical work. The company's innovative solutions are designed to support sales representatives and technicians in the field, ultimately improving sales efficiency and closing rates.
SpearFysh
Pre Seed Round in 2011
SpearFysh, Inc., based in Twinsburg, Ohio, develops sales force automation tools designed to enhance business effectiveness and efficiency. The company's flagship product, SpearFysh, is a web-based application that enables executives, sales managers, and salespeople to manage, share, coach, and search conversations that have been machine analyzed. SpearFysh also offers a tablet device that captures field sales interactions in real-time, allowing organizations to share, search, and analyze customer and prospect interactions. Founded by Marc Miller, the company leverages proprietary software to translate captured sales interactions into valuable business intelligence, aiming to increase sales, accelerate selling cycles, and improve win rates. SpearFysh's technology supports various industries, including sales, consulting, healthcare, financial services, training, human resources, and hospitality.
Anderson Aerospace
Seed Round in 2011
Anderson Aerospace is a Kent, Ohio-based company specializing in the design and manufacture of advanced satellite antenna systems for the aviation industry. Founded to explore new opportunities in aerospace, advanced manufacturing, and satellite communications, the company boasts a team with over 140 years of collective experience, including 82 years specifically in the design, manufacture, and sale of aircraft satellite antenna systems. Their products are engineered to comply with the latest ARINC antenna specifications for large fuselage-mounted designs, allowing clients to achieve reductions in weight and power consumption while minimizing operational and installation costs.
Cervilenz
Venture Round in 2011
CerviLenz is a new, disposable device that measure vaginal cervical length during a speculum exam. Cervical length is a powerful predictor of preterm birth risk and influences patient management decisions. CerviLenz gives clinicians an immediate, reliable method for measuring the cervix at the point of care. CerviLenz is manufactured and distributed by Cervilenz Inc. headquartered in Chagrin Falls, Ohio.
Segmint
Venture Round in 2011
Segmint, Inc. is a data-driven technology company based in Cuyahoga Falls, Ohio, that specializes in providing customer insights through advanced data tagging, categorization, and contextualization. Founded in 2007, Segmint empowers financial institutions and fintech providers to effectively leverage customer data, enabling them to enhance customer interactions and measure marketing outcomes. The company's product suite includes Merchant Payment Cleansing, Transaction Analytics, and a Data-Driven Marketing Platform, along with solutions for competitor analysis, customer onboarding, and personalized marketing. Segmint's platform delivers targeted messages across various channels while adhering to privacy and security standards. With insights derived from billions of transactions, the company serves a diverse range of industries, including banking, retail, media, and insurance, helping organizations inform their strategies in competitive analysis, risk management, and product innovation.
CardioInsight Technologies
Series B in 2011
CardioInsight Technologies Inc. is a medical device company based in Cleveland, Ohio, specializing in non-invasive cardiac mapping systems. The company has developed a technology called Electrocardiographic Mapping (ECM), which generates three-dimensional images of the heart's electrical activity by integrating body surface electrical data with anatomical data obtained from CT scans. The CardioInsight system employs a single-use disposable multi-sensor vest to capture electrical signals from the body surface, enabling the creation of detailed epicardial 3D electroanatomic maps and virtual electrograms. This innovative approach allows physicians to visualize real-time cardiac electrical activity and enhances the accuracy of diagnosing and treating conditions such as arrhythmias and congestive heart failure. CardioInsight's technology has been validated through over 260 patient studies, demonstrating its effectiveness in guiding therapeutic interventions. Founded in 2006, the company operates as a subsidiary of Medtronic plc.
Thermalin
Series A in 2011
Thermalin, Inc. is a biotechnology company based in Cleveland, Ohio, founded in 2010, that focuses on developing innovative insulin therapies for individuals with Type 1 and Type 2 diabetes. The company aims to transform the insulin and insulin delivery market, valued at $30 billion, through its cutting-edge, highly concentrated, ultra-rapid acting insulin and a novel glucose management system that is the size of a postage stamp. This insulin can also be utilized in existing insulin pumps, enhancing their efficiency. In addition to its lead program, Thermalin is exploring partnerships to create no-cold-chain basal and mix insulins, as well as glucose-responsive insulins. Its products are designed to be rapidly absorbing and do not require refrigeration, thereby reducing the burden of insulin therapy and improving patient adherence and health outcomes.
MedCity News
Seed Round in 2010
MedCity News creates content for people who care about health care.
It is a solution for media companies and organizations that need content, stakeholders who need actionable information about the medical industry, and advertisers who want to speak to this valuable niche audience.
Founded by veteran journalists with both health care reporting and online editorial experience, MedCity News is poised to build an innovative new-media enterprise capable of taking advantage of these converging forces while building a profitable national business and brand.
It operates the MedCity News Service, a type of niche wire service focused on the innovation economies in major "medical cities" and states (it has offices in Minnesota and Ohio, but also covers dealflow in the Midwest and Pittsburgh). It also operates MedCityNews.com and a custom content service that creates made-to-order content for anyone that wants it.
Its news content is syndicated throughthe Ohio News Network, Akron Beacon Journal, The Kindle, WKYC, the Boston online journal MassDevice and the Zemanta blog aggregator, among others.
Thermalin
Venture Round in 2010
Thermalin, Inc. is a biotechnology company based in Cleveland, Ohio, founded in 2010, that focuses on developing innovative insulin therapies for individuals with Type 1 and Type 2 diabetes. The company aims to transform the insulin and insulin delivery market, valued at $30 billion, through its cutting-edge, highly concentrated, ultra-rapid acting insulin and a novel glucose management system that is the size of a postage stamp. This insulin can also be utilized in existing insulin pumps, enhancing their efficiency. In addition to its lead program, Thermalin is exploring partnerships to create no-cold-chain basal and mix insulins, as well as glucose-responsive insulins. Its products are designed to be rapidly absorbing and do not require refrigeration, thereby reducing the burden of insulin therapy and improving patient adherence and health outcomes.
TheraVasc
Series A in 2010
TheraVasc Inc. is a pharmaceutical company based in Cleveland, Ohio, focused on developing treatments for chronic vascular diseases. Incorporated in 2009, the company specializes in repurposing existing drugs to address unmet medical needs. Its primary product, TV1001, is an oral formulation of sodium nitrite that targets conditions such as peripheral artery disease and diabetic neuropathy. This formulation aims to improve blood flow to the extremities, facilitating better management of diabetic complications and promoting wound healing. By concentrating on underserved markets, TheraVasc seeks to provide effective solutions for patients suffering from various vascular disorders.
Laguna Pharmaceuticals
Seed Round in 2010
Laguna Pharmaceuticals Inc. is a biopharmaceutical company focused on the development and marketing of small molecule pharmaceuticals, specifically targeting the treatment of atrial fibrillation (AF) and atrial flutter (AFL). The company, originally established as ChanRx Corp. in 2006, rebranded to its current name in February 2015. With its headquarters in La Jolla, California, Laguna Pharmaceuticals is dedicated to advancing therapeutic options for patients suffering from these common cardiac conditions, which can lead to serious health complications such as heart attacks and strokes.
Echogen Power Systems
Series A in 2010
Echogen Power Systems, LLC is a developer of innovative heat-to-power generation systems that efficiently capture and convert waste heat into usable electricity. Founded in 2007 and based in Akron, Ohio, the company specializes in solutions for various applications, including gas turbines, industrial waste heat recovery, solar thermal, geothermal, and hybrid alternatives to internal combustion engines. Echogen's technology utilizes a carbon dioxide heat pump cycle to create emission-free renewable electricity, enabling clients to monetize their otherwise wasted heat and improve their energy returns. The company caters to businesses that produce heat as a byproduct of their processes, providing scalable and cost-effective energy solutions.
Checkpoint Surgical
Series A in 2010
Checkpoint Surgical Inc., established in 2009 and headquartered in Cleveland, Ohio, specializes in manufacturing neuro devices for surgeons. Their primary products are CHECKPOINT 9094 and CHECKPOINT 9394, both designed to locate, identify, and evaluate motor nerve tissue and muscle function during complex surgical procedures. These devices cater to various applications such as head and neck surgeries, hand and extremities procedures, targeted muscle re-innervation, orthopedic oncology and trauma, and plastic reconstruction. The company sells its products through a network of distributors in the United States, aiming to enhance patient outcomes by providing surgeons with precise nerve stimulation and monitoring equipment.
ABSMaterials
Series A in 2010
ABS Materials designs, develops, and delivers solutions for ground, surface, and municipal water contamination. Its solutions include VoC-Eater system, which destroys pharmaceuticals, chlorinated solvents, herbicides, endocrine disruptors, PCBs, dyes, and phenols to outflow clean water; Osorb, a solution to destroy persistent organic pollutants in the groundwater; and Iron-Osorb, an inert sand-like glass used on TCE/PCE/DCE/PCBs. The company’s solutions are used to clean solvents, pesticides, and other persistent organic pollutants from the water, soil, and air. It offers its systems on a rental and long term lease basis.
The company was founded in 2008 and is based in Wooster, Ohio with an additional office in Houston, Texas.
Melody Management
Seed Round in 2010
Melody Management LLC is a company based in Columbus, Ohio, that specializes in providing technology services for managing music careers. It offers a centralized music management console, which includes tools such as Melody Music Desk and Melody Card, a payment system designed for the distributed music business. These professional management tools assist artists in establishing a consistent online presence by enabling them to upload music, photos, videos, and news updates to keep their fans informed.
TheraVasc
Seed Round in 2010
TheraVasc Inc. is a pharmaceutical company based in Cleveland, Ohio, focused on developing treatments for chronic vascular diseases. Incorporated in 2009, the company specializes in repurposing existing drugs to address unmet medical needs. Its primary product, TV1001, is an oral formulation of sodium nitrite that targets conditions such as peripheral artery disease and diabetic neuropathy. This formulation aims to improve blood flow to the extremities, facilitating better management of diabetic complications and promoting wound healing. By concentrating on underserved markets, TheraVasc seeks to provide effective solutions for patients suffering from various vascular disorders.
Electron Database
Seed Round in 2009
Electron Database Company (EDC) is a Cleveland, Ohio-based company building advanced software technology designed to dramatically improve the performance of enterprise applications, data warehouses and cloud computing infrastructures. EDC's patented technology is expected to deliver over 40 times faster performance on existing disk-based hardware versus existing database software and over 400 times faster performance on advanced, solid-state based hardware currently in development. Once released, EDC's technology will be the only database that fully leverages multi-core technology, 64-Bit computing, and solid-state memory drives that are expected to transform the hardware market and deliver material gains in energy efficiency.
Checkpoint Surgical
Series A in 2009
Checkpoint Surgical Inc., established in 2009 and headquartered in Cleveland, Ohio, specializes in manufacturing neuro devices for surgeons. Their primary products are CHECKPOINT 9094 and CHECKPOINT 9394, both designed to locate, identify, and evaluate motor nerve tissue and muscle function during complex surgical procedures. These devices cater to various applications such as head and neck surgeries, hand and extremities procedures, targeted muscle re-innervation, orthopedic oncology and trauma, and plastic reconstruction. The company sells its products through a network of distributors in the United States, aiming to enhance patient outcomes by providing surgeons with precise nerve stimulation and monitoring equipment.
Inspiron Logistics
Seed Round in 2009
Inspiron Logistics LLC is a provider of wireless emergency notification systems designed to facilitate instant communication during emergencies. Founded in 2003 and based in Cuyahoga Falls, Ohio, the company offers a technology that utilizes text messaging protocols, voice calls, email, NOAA alerts, and GIS mapping to deliver timely alerts and information. Its systems are tailored for local governments, schools, colleges, companies, and municipalities, enabling officials to effectively manage and disseminate emergency notifications to users with registered profiles. By leveraging multiple communication channels, Inspiron Logistics ensures that critical information reaches individuals swiftly and reliably in times of need.
MesoCoat
Seed Round in 2009
MesoCoat, Inc. is a surface engineering company based in Euclid, Ohio, that specializes in metal protection and repair services through advanced thermal spray coatings and metallurgical cladding technologies. Founded in 2007, the company produces a variety of cladding products made from corrosion-resistant alloys and stainless steel, as well as wear-resistant materials like chromium carbide and tungsten carbide. MesoCoat also offers low thickness clad products and heat-resistant cladding solutions using aluminide and nickel alloys. In addition to these products, the company provides coating solutions, including particulate composite powders, and thermal spray coating services. MesoCoat serves a wide range of industries, including oil and gas, aerospace, defense, transportation, and infrastructure, among others. The company operates as a subsidiary of Abakan, Inc.
MAR Systems
Seed Round in 2008
MAR Systems, founded in 2006 and headquartered in Cleveland, Ohio, specializes in advanced water purification technology aimed at removing harmful metal contaminants such as mercury, selenium, and arsenic from water and industrial waste streams. The company has developed a patented process utilizing its proprietary Sorbster media technology, which effectively chemisorbs these contaminants, allowing clients to meet stringent EPA standards. This innovative approach not only enhances water purification but also provides a non-hazardous option for the disposal of removed contaminants. Co-developed with the EPA, MAR Systems' technology is quickly establishing itself as a standard in the water treatment industry, offering cost-efficient solutions for clients seeking to improve water quality.
Juventas Therapeutics
Seed Round in 2008
Juventas Therapeutics is a privately-held clinical-stage biotechnology company developing regenerative therapies. Founded in 2007, it focuses on treating life-threatening diseases using non-viral gene therapies that activate natural processes to repair the body.
Cervilenz
Seed Round in 2008
CerviLenz is a new, disposable device that measure vaginal cervical length during a speculum exam. Cervical length is a powerful predictor of preterm birth risk and influences patient management decisions. CerviLenz gives clinicians an immediate, reliable method for measuring the cervix at the point of care. CerviLenz is manufactured and distributed by Cervilenz Inc. headquartered in Chagrin Falls, Ohio.
STACK Media Powered by Stack Sports
Series A in 2008
STACK Media, Inc. specializes in providing sports performance, training, and lifestyle content tailored for high school athletes and the broader sports community. Founded in 2005 and headquartered in Cleveland, Ohio, the company offers valuable resources on training, nutrition, and life skills, including team building, goal setting, and mental preparation. By addressing both athletic and personal development, STACK Media empowers athletes to reach their full potential, whether they aim to make their team, secure scholarships, or pursue professional careers. The company operates through various platforms, including magazines, websites, and events, and features STACK Varsity, a social content platform that enables high school teams and athletes to create and share content. STACK Media has established strategic partnerships with organizations such as Varsity Networks and Yahoo! Sports to further enhance its offerings and impact on the culture of high school sports in the United States.
CardioInsight Technologies
Series A in 2008
CardioInsight Technologies Inc. is a medical device company based in Cleveland, Ohio, specializing in non-invasive cardiac mapping systems. The company has developed a technology called Electrocardiographic Mapping (ECM), which generates three-dimensional images of the heart's electrical activity by integrating body surface electrical data with anatomical data obtained from CT scans. The CardioInsight system employs a single-use disposable multi-sensor vest to capture electrical signals from the body surface, enabling the creation of detailed epicardial 3D electroanatomic maps and virtual electrograms. This innovative approach allows physicians to visualize real-time cardiac electrical activity and enhances the accuracy of diagnosing and treating conditions such as arrhythmias and congestive heart failure. CardioInsight's technology has been validated through over 260 patient studies, demonstrating its effectiveness in guiding therapeutic interventions. Founded in 2006, the company operates as a subsidiary of Medtronic plc.
Inspiron Logistics
Venture Round in 2008
Inspiron Logistics LLC is a provider of wireless emergency notification systems designed to facilitate instant communication during emergencies. Founded in 2003 and based in Cuyahoga Falls, Ohio, the company offers a technology that utilizes text messaging protocols, voice calls, email, NOAA alerts, and GIS mapping to deliver timely alerts and information. Its systems are tailored for local governments, schools, colleges, companies, and municipalities, enabling officials to effectively manage and disseminate emergency notifications to users with registered profiles. By leveraging multiple communication channels, Inspiron Logistics ensures that critical information reaches individuals swiftly and reliably in times of need.
Aria Analytics
Series B in 2007
Aria Analytics, Inc. develops and commercializes analytical technology to characterize liquids for healthcare and industrial applications. The company’s Aria technology is used for testing of raw materials, manufacturing process, contaminated products, counterfeit drugs and finished goods. Aria Analytics also offers subassembly systems and software for automated analytical diagnostics. It serves specialty chemical, healthcare, pharmaceuticals, and counterfeit product markets.
The company was founded in 2003 and is based in Cleveland, Ohio. Aria Analytics, Inc. is a former subsidiary of 5iTech, LLC.
HF Food Technologies
Seed Round in 2007
HF Food Technologies, Ltd. is a Cleveland, Ohio-based company that specializes in developing and marketing seasonings, coatings, sauces, and various food specialties. Established in 1981, the company focuses on enhancing food flavor while reducing fat content, offering innovative products such as Nutrigras, which allows for the one-to-one replacement of fat in meat products like beef and pork. HF Food Technologies distributes its products through retail stores in several states, including Chicago, Alabama, Georgia, South Carolina, and Tennessee, in addition to operating an online store.
Echogen Power Systems
Seed Round in 2007
Echogen Power Systems, LLC is a developer of innovative heat-to-power generation systems that efficiently capture and convert waste heat into usable electricity. Founded in 2007 and based in Akron, Ohio, the company specializes in solutions for various applications, including gas turbines, industrial waste heat recovery, solar thermal, geothermal, and hybrid alternatives to internal combustion engines. Echogen's technology utilizes a carbon dioxide heat pump cycle to create emission-free renewable electricity, enabling clients to monetize their otherwise wasted heat and improve their energy returns. The company caters to businesses that produce heat as a byproduct of their processes, providing scalable and cost-effective energy solutions.
Embrace Pet Insurance
Seed Round in 2007
Founded in 2003, Embrace specializes in comprehensive pet insurance for dogs and cats across the United States. Its policies cover a wide range of incidents and illnesses, including accidents, genetic conditions, alternative therapies, chronic illnesses, and diagnostic tests.
Logos Energy
Series A in 2007
Logos Energy, Inc. is an alternative energy company based in Highland Heights, Ohio, with a focus on developing innovative products utilizing fuel cells and alternative liquid fuels. Founded in 2004, the company specializes in novel direct carbon fuel cell technology aimed at the efficient creation, storage, and delivery of electrical power. In addition to its headquarters, Logos Energy operates a research laboratory in St. Louis, where it conducts advanced energy research and product development. As a mid-sized organization, it is dedicated to advancing sustainable energy solutions.
Telerad Express
Seed Round in 2007
Telerad Express provides remote daytime radiology interpretations in multiple modalities to imaging centers, hospitals, and medical practices.
Telerad Express was founded in 2006 and is based in Beachwood, Ohio, United States.
MAR Systems
Seed Round in 2007
MAR Systems, founded in 2006 and headquartered in Cleveland, Ohio, specializes in advanced water purification technology aimed at removing harmful metal contaminants such as mercury, selenium, and arsenic from water and industrial waste streams. The company has developed a patented process utilizing its proprietary Sorbster media technology, which effectively chemisorbs these contaminants, allowing clients to meet stringent EPA standards. This innovative approach not only enhances water purification but also provides a non-hazardous option for the disposal of removed contaminants. Co-developed with the EPA, MAR Systems' technology is quickly establishing itself as a standard in the water treatment industry, offering cost-efficient solutions for clients seeking to improve water quality.
Stanton Advanced Ceramics
Angel Round in 2007
Stanton Advanced Ceramics manufactures industrial ceramics that are used in heating and cooling applications such as in glass or steel making. The company offers proprietary thermally shock resistant, high temperature ceramic matrix composite (CMC) technologies.
Stanton Advanced Ceramics was founded in 2001 and is based in Cleveland, Ohio.
Embrace Pet Insurance
Seed Round in 2007
Founded in 2003, Embrace specializes in comprehensive pet insurance for dogs and cats across the United States. Its policies cover a wide range of incidents and illnesses, including accidents, genetic conditions, alternative therapies, chronic illnesses, and diagnostic tests.
Banyan Technology
Series B in 2007
Banyan Technology provides web-based logistics solutions that connect manufacturers, distributors, and third-party logistics providers with their preferred freight carriers. Its platform includes Carrier Connect, a freight management and profitability toolkit linking shippers to carriers; Client Connect, which helps 3PLs attract and retain clients through client-specific connections; and Digital Broker, a carrier-sourcing tool for 3PLs and high-volume truckload shippers. The company emphasizes carrier neutrality and focuses on moving information between business systems and people to enable faster, better-informed freight decisions. The solution enables live carrier connections and direct quotes from multiple carriers for each shipment, driving operational efficiency and profitability. Banyan Technology serves direct manufacturers and distributors, 3PLs, and related logistics stakeholders, and is based in Elyria, Ohio.
Banyan Technology
Series A in 2006
Banyan Technology provides web-based logistics solutions that connect manufacturers, distributors, and third-party logistics providers with their preferred freight carriers. Its platform includes Carrier Connect, a freight management and profitability toolkit linking shippers to carriers; Client Connect, which helps 3PLs attract and retain clients through client-specific connections; and Digital Broker, a carrier-sourcing tool for 3PLs and high-volume truckload shippers. The company emphasizes carrier neutrality and focuses on moving information between business systems and people to enable faster, better-informed freight decisions. The solution enables live carrier connections and direct quotes from multiple carriers for each shipment, driving operational efficiency and profitability. Banyan Technology serves direct manufacturers and distributors, 3PLs, and related logistics stakeholders, and is based in Elyria, Ohio.
Nine Iron Innovations
Seed Round in 2006
Nine Iron Innovations provides automated mobile video monitoring systems for golf course contests and events. The company’s product portfolio includes VerishotMobile, a golf shot video monitoring, contest, and marketing program for golf courses, event managers, golf management organizations, and independent representatives; and Sharegolf.com, a social networking site that connects golf courses and golfers, and allows them to view and share videos of their swings with other members.
Nine Iron Innovations was founded in 2004 and is based in Ohio, United States.
FLX Micro
Venture Round in 2006
FLX Micro manufactures silicon carbide-based microsensors. The company develops its products through silicon carbide deposition and microfabrication technology platform. Its products are used in various applications, such as automotive, energy, environmental, and manufacturing. The company was formerly known as Fiberlead, Inc. FLX Micro, Inc. was founded in 2000 and is headquartered in Cleveland, Ohio.
HF Food Technologies
Seed Round in 2006
HF Food Technologies, Ltd. is a Cleveland, Ohio-based company that specializes in developing and marketing seasonings, coatings, sauces, and various food specialties. Established in 1981, the company focuses on enhancing food flavor while reducing fat content, offering innovative products such as Nutrigras, which allows for the one-to-one replacement of fat in meat products like beef and pork. HF Food Technologies distributes its products through retail stores in several states, including Chicago, Alabama, Georgia, South Carolina, and Tennessee, in addition to operating an online store.
Delta Plant Technologies
Seed Round in 2006
Delta Plant Technologies, established in 2003 and headquartered in Akron, Ohio, specializes in producing ethanol as an alternative fuel source from the liquid byproduct stream of its natural rubber production process. The company focuses on developing agronomics and processing technologies to produce both natural rubber and fuel ethanol feedstock in North America.
Embrace Pet Insurance
Seed Round in 2006
Founded in 2003, Embrace specializes in comprehensive pet insurance for dogs and cats across the United States. Its policies cover a wide range of incidents and illnesses, including accidents, genetic conditions, alternative therapies, chronic illnesses, and diagnostic tests.
Synapse Biomedical
Seed Round in 2006
Synapse Biomedical Inc. is a medical device company based in Oberlin, Ohio, founded in 2002. It specializes in the research, development, and commercialization of neurostimulation products aimed at improving the quality of life for individuals with neurological impairments, such as spinal cord injuries and Amyotrophic Lateral Sclerosis. The company's flagship product, the NeuRx Diaphragm Pacing System, utilizes a minimally invasive outpatient procedure to enhance breathing patterns in patients. Additionally, Synapse Biomedical has developed the TransAeris System, a temporary diaphragm stimulator designed for patients at risk of or requiring prolonged mechanical ventilation. The company's innovations stem from extensive research conducted at Case Western Reserve University and University Hospitals of Cleveland, contributing to advancements in the treatment of chronic respiratory insufficiency.
Knotice
Venture Round in 2006
Knotice is a direct digital marketing services and software company based in Akron, Ohio, specializing in relevant marketing communications tailored to individual consumers. The company has developed a cloud-based platform known as Concentri®, which integrates multiple marketing channels, including mobile, web, and email, allowing marketers to create and manage targeted, multi-stage communications efficiently. Knotice's approach emphasizes personalization and process automation to enhance the return on investment for direct digital marketing efforts. Concentri® offers a range of features such as onsite targeting, testing and optimization, email and mobile marketing, landing page management, and universal profile management, all within a unified environment. This comprehensive platform aims to foster customer loyalty, strengthen relationships, and drive sales opportunities through individualized digital messaging.
ComSense Technology
Seed Round in 2005
ComSense Technology manufactures high temperature pressure sensors that enable the precision control of diesel, gasoline, and turbine engines. This results in improved fuel efficiency and reduced emissions.
ComSense Technology is based in Cleveland, Ohio, United States.
Stanton Advanced Ceramics
Seed Round in 2005
Stanton Advanced Ceramics manufactures industrial ceramics that are used in heating and cooling applications such as in glass or steel making. The company offers proprietary thermally shock resistant, high temperature ceramic matrix composite (CMC) technologies.
Stanton Advanced Ceramics was founded in 2001 and is based in Cleveland, Ohio.
Stanton Advanced Ceramics
Seed Round in 2004
Stanton Advanced Ceramics manufactures industrial ceramics that are used in heating and cooling applications such as in glass or steel making. The company offers proprietary thermally shock resistant, high temperature ceramic matrix composite (CMC) technologies.
Stanton Advanced Ceramics was founded in 2001 and is based in Cleveland, Ohio.