JumpStart Inc. is a non-profit organization based in Cleveland, Ohio, dedicated to enhancing the economic impact of entrepreneurial ventures and the ecosystems that support them. Founded in 2004, the organization provides intensive entrepreneurial development assistance to Ohio entrepreneurs leading high-potential, early-stage companies. JumpStart is committed to fostering economic inclusion by focusing on the success of minority and women entrepreneurs in building high-impact businesses. In addition to direct support for entrepreneurs, JumpStart works to strengthen Ohio's innovation and entrepreneurial ecosystem by securing resources and collaborating with community and regional leaders to promote the growth of high-growth companies. Through these efforts, JumpStart aims to create significant and sustainable economic impacts across the region.
Asynt Solutions creates innovative, safe, and efficient solutions for transportation infrastructure and construction. The company was founded in 2021 and is headquartered in Columbus, Ohio, United States.
Axuall
Series A in 2021
Axuall, Inc. is a workforce intelligence company that operates a digital network designed to verify identities, credentials, and authenticity across various sectors, including healthcare, insurance, and logistics. Founded in 2018 and based in Cleveland, Ohio, Axuall offers an integrated platform that facilitates smarter decision-making and expedites the onboarding process for healthcare providers. By leveraging real-time practitioner data, the company enhances workforce deployment and efficiency, and provides critical insights for network planning, analytics, and reporting. Its solutions aim to empower healthcare professionals by granting them control over their career identities while connecting health systems, staffing firms, and telehealth organizations to valuable data resources.
S4 Medical
Series A in 2021
S4 Medical Corp. is a medical device company based in Cleveland, Ohio, founded in 2017. The company specializes in developing innovative solutions for catheter ablation treatment, specifically targeting atrial fibrillation. Its primary product, the eSolution device, is designed to minimize complications to the esophagus during ablation procedures. This device allows healthcare providers to protect the esophagus and aids electrophysiologists in determining the necessary adjustments for effective treatment. S4 Medical's focus on enhancing patient safety in cardiac procedures reflects its commitment to improving outcomes in the field of electrophysiology.
ReadySet Surgical
Series A in 2020
ReadySet Surgical LLC is a company based in Cincinnati, Ohio, that specializes in cloud-based software solutions for managing surgical vendor inventory. The platform enhances coordination and communication among surgical teams, sterilization departments, and medical device vendors, ensuring that every procedure is equipped with the correct contracted inventory and documentation. ReadySet Surgical also offers RS Analyze, a tool for hospitals to evaluate vendor performance and detect off-contract implant purchases through real-time data analytics, allowing for timely corrective actions. The company focuses on providing a user-friendly experience and seamless installation for hospital staff and vendor representatives. Established in 2014, ReadySet Surgical aims to improve the efficiency and transparency of the surgical supply chain, ultimately reducing delays and errors in surgical procedures.
S4 Medical
Venture Round in 2020
S4 Medical Corp. is a medical device company based in Cleveland, Ohio, founded in 2017. The company specializes in developing innovative solutions for catheter ablation treatment, specifically targeting atrial fibrillation. Its primary product, the eSolution device, is designed to minimize complications to the esophagus during ablation procedures. This device allows healthcare providers to protect the esophagus and aids electrophysiologists in determining the necessary adjustments for effective treatment. S4 Medical's focus on enhancing patient safety in cardiac procedures reflects its commitment to improving outcomes in the field of electrophysiology.
Able (formerly EmployStream)
Series B in 2020
EmployStream is a hiring workflow automation software platform for staffing companies and other high-volume employers. It also creates high-quality, user-friendly for high-volume employers that automates the hiring and onboarding process for employers. The platform eliminates costly mistakes and delays allowing companies to hire up to 90% faster and at half the cost. The company provides an online hiring platform which offers different features such as paper onboarding, real-time alerting, online application, background checks, applicant pre & interview screening, and verification. EmployStream was founded in 2014 and is headquartered in Cleveland Ohio, USA.
MedPilot
Seed Round in 2019
MedPilot Inc. is a Cleveland-based company founded in 2014 that provides an AI-driven patient relationship management platform. The company focuses on simplifying administrative and billing processes for healthcare providers and patients. MedPilot's platform features a payment system that clearly explains patient obligations and the reasons behind them. Additionally, it includes post-payment surveys that gather meaningful feedback on the patient experience. The platform also supports patients through a network of navigators who offer billing discounts, customizable payment plans, and advocacy services. By streamlining medical payments and addressing payment-related challenges, MedPilot aims to enhance the overall experience for both patients and healthcare providers.
Vitalxchange
Pre Seed Round in 2019
Vitalxchange, Inc. is a company based in North Royalton, Ohio, focused on developing a virtual platform designed to assist parents of children with autism and developmental disabilities. Established in 2018, the platform offers a unique blend of human expertise and a proprietary expert system to support families in navigating their child's developmental, behavioral, learning, and overall well-being. Each family is paired with a team of VitalGuides, who provide comprehensive support throughout the parenting journey, helping to identify issues early and facilitating connections with clinical or educational providers for diagnosis and treatment. The service covers a wide range of parenting topics, from behavioral challenges to disability planning, and is accessible through a monthly subscription model available directly or via employer benefits programs.
Able (formerly EmployStream)
Series A in 2019
EmployStream is a hiring workflow automation software platform for staffing companies and other high-volume employers. It also creates high-quality, user-friendly for high-volume employers that automates the hiring and onboarding process for employers. The platform eliminates costly mistakes and delays allowing companies to hire up to 90% faster and at half the cost. The company provides an online hiring platform which offers different features such as paper onboarding, real-time alerting, online application, background checks, applicant pre & interview screening, and verification. EmployStream was founded in 2014 and is headquartered in Cleveland Ohio, USA.
enosiX
Series B in 2018
enosiX, Inc. specializes in creating integration solutions that connect front-end platforms, particularly Salesforce, with SAP systems. Founded in 2014 and based in Cincinnati, Ohio, the company offers a range of products designed to facilitate seamless data access and business process flows. Their solutions include Enosix Connect for cloud application integration, Enosix Engage for real-time SAP data access without middleware, and various tools for managing sales processes, such as Enosix Sales CPQ, which utilizes SAP data for pricing and quotes. By enabling real-time data sharing, enosiX enhances productivity and customer engagement, allowing sales teams to respond more quickly to opportunities. The company's platform minimizes coding requirements and provides bi-directional integration, ensuring that businesses can leverage SAP data efficiently across various functions, including order management and logistics. Additionally, enosiX supports mobile access to SAP data, empowering a mobile workforce to improve customer relationships and overall productivity.
Mezu
Venture Round in 2018
Mezu, Inc., established in 2017 and based in Cleveland Heights, Ohio, operates in the banking industry with a focus on mobile payments. The company offers a secure and private mobile payment app that allows users to send and receive money without revealing personal information. This platform enables users to pay, tip, earn, and donate easily and at no cost, prioritizing user privacy and discretion in financial transactions. Mezu's app is accessible on both iOS and Android devices in the United States, reflecting its commitment to providing a cash-like experience in digital payments.
Wisr
Seed Round in 2017
Wisr Inc. operates an online platform that enhances alumni engagement and student outcomes for higher education institutions. Founded in 2016 and based in Rocky River, Ohio, Wisr facilitates digital coaching by connecting current students with alumni, allowing for personalized guidance in career development. Its platform supports career services and alumni relations offices by automating the matching process, scheduling, and follow-up communications. This approach enables students to build a personal board of advisors, fostering meaningful connections that can positively influence their career paths.
Able (formerly EmployStream)
Seed Round in 2017
EmployStream is a hiring workflow automation software platform for staffing companies and other high-volume employers. It also creates high-quality, user-friendly for high-volume employers that automates the hiring and onboarding process for employers. The platform eliminates costly mistakes and delays allowing companies to hire up to 90% faster and at half the cost. The company provides an online hiring platform which offers different features such as paper onboarding, real-time alerting, online application, background checks, applicant pre & interview screening, and verification. EmployStream was founded in 2014 and is headquartered in Cleveland Ohio, USA.
Neuros Medical
Series A in 2017
Neuros Medical, Inc. is a neuromodulation company based in Willoughby Hills, Ohio, that specializes in developing proprietary neurostimulation therapies aimed at addressing unmet medical needs for patients globally. The company's flagship technology, known as Electrical Nerve Block, targets chronic pain conditions, including neuroma and residual limb pain, chronic post-surgical pain, and chronic migraine. Neuros Medical also offers the Neuros Altius System, which features an implantable generator with an integrated rechargeable battery, a cuff electrode, and associated external devices. Established in 2008, the company is dedicated to advancing innovative solutions for pain management.
Wisr
Seed Round in 2017
Wisr Inc. operates an online platform that enhances alumni engagement and student outcomes for higher education institutions. Founded in 2016 and based in Rocky River, Ohio, Wisr facilitates digital coaching by connecting current students with alumni, allowing for personalized guidance in career development. Its platform supports career services and alumni relations offices by automating the matching process, scheduling, and follow-up communications. This approach enables students to build a personal board of advisors, fostering meaningful connections that can positively influence their career paths.
StreamLink Software
Venture Round in 2016
StreamLink Software-is a Software-as-a-Service company that develops grant management software for nonprofits and the public sector. Ther grants management solution, AmpliFund, is designed for managing every stage of the grant lifecycle and is at the forefront of automating grant compliance and data standardization in the public sector. It was founded in 2008 and is headquartered in Cleveland, Ohio.
ExpenseBot
Seed Round in 2016
ExpenseBot Inc. is a company that offers an expense management platform aimed at simplifying business expense reporting. Founded in 2013 and headquartered in Shaker Heights, Ohio, ExpenseBot's software automates the creation and approval of expense reports by integrating data from various sources such as calendar applications, emails, credit card transactions, and GPS data. Utilizing artificial intelligence, the platform analyzes expense data to identify reimbursable items and generates reports automatically when certain thresholds are met. This technology helps users save time and reduces the complexity associated with organizing and submitting expense reports, ultimately enhancing the efficiency of expense management for businesses.
Milo Biotechnology
Venture Round in 2016
MILO BIOTECHNOLOGY Milo Biotechnology is a Cleveland-based company dedicated to improving the lives of patients with neuromuscular diseases. Milo's early clinical stage follistatin program, exclusively licensed from Nationwide Children's Hospital, is designed to increase muscle size and strength.
StreamLink Software
Venture Round in 2016
StreamLink Software-is a Software-as-a-Service company that develops grant management software for nonprofits and the public sector. Ther grants management solution, AmpliFund, is designed for managing every stage of the grant lifecycle and is at the forefront of automating grant compliance and data standardization in the public sector. It was founded in 2008 and is headquartered in Cleveland, Ohio.
Zuga
Seed Round in 2013
Zuga Medical Inc. specializes in designing, manufacturing, and marketing innovative dental implant systems aimed at simplifying the implant process. The company's offerings include a range of products such as bone level dental implants, abutments, implant toolkits, bone grafts, and surgical instruments. Their patent-pending system utilizes a surgical-grade titanium threaded rod that can be inserted directly into the jaw, allowing dentists to deliver implant services more efficiently without the need for complex alignment systems or outsourced laboratory services. Zuga Medical also provides training services to dental professionals. Founded in 2009 and headquartered in Beachwood, Ohio, the company sells its products directly and online in the United States, as well as through distributor partnerships in China.
Intellirod Spine
Seed Round in 2013
Intellirod Spine, Inc. is a biomedical company based in Akron, Ohio, focused on developing and commercializing a wireless implantable microelectronic sensor specifically designed for lumbar spine fusion. The company's primary product, the IntelliRod system, is an implanted sensor that attaches to spinal fusion implants and measures the load on the rod, providing surgeons with real-time data on the progress of spinal fusion. This innovative technology enables spine surgeons to accurately assess the success of the fusion process, thereby reducing the need for unnecessary post-operative CT scans and exploratory surgeries. By offering objective insights into rod strain, Intellirod Spine aims to improve patient outcomes and decrease overall healthcare costs associated with postoperative care. The company was originally established as OrthoData, Inc. in 2003.
Casentric
Convertible Note in 2013
Casentric, LLC is a software company based in Shaker Heights, Ohio, specializing in claims management solutions for the property and casualty insurance industry. The company's flagship product, CaseXpert, is a cloud-based application that enhances the evaluation and resolution of third-party personal injury and property damage claims. CaseXpert integrates components for assessing liability, damages, and provides reporting and negotiation guidance, allowing claims handlers to make informed decisions efficiently. By offering a user-friendly interface, CaseXpert addresses the industry's challenges, such as variability in claims outcomes and a shortage of experienced adjusters. The software aims to streamline the claims process, reduce costs, and improve settlement accuracy for insurance companies and self-insured organizations. Since its inception in 2009, Casentric has engaged multiple pilots with clients, demonstrating significant reductions in claims costs and improved operational efficiencies. The firm has received funding from its founders and local venture associations to support its growth and development.
Guided Interventions
Seed Round in 2013
Guided Interventions is a Cleveland-based medical device startup focused on developing innovative wire-based medical devices aimed at enhancing the efficacy and safety of interventional procedures. Led by CEO Dr. Matthew Pollman, the company specializes in a fractional flow reserve (FFR) guidewire that facilitates accurate FFR measurements during coronary catheterization. This device is designed to improve maneuverability and handling, thereby enabling healthcare professionals to assess the physiological impact of coronary artery blockages more effectively. By minimizing the use of stents and reducing the risks associated with heart surgery, Guided Interventions aims to lower costs and improve patient outcomes in the treatment of cardiovascular conditions.
MedCity News
Seed Round in 2012
MedCity News creates content for people who care about health care. It is a solution for media companies and organizations that need content, stakeholders who need actionable information about the medical industry, and advertisers who want to speak to this valuable niche audience. Founded by veteran journalists with both health care reporting and online editorial experience, MedCity News is poised to build an innovative new-media enterprise capable of taking advantage of these converging forces while building a profitable national business and brand. It operates the MedCity News Service, a type of niche wire service focused on the innovation economies in major "medical cities" and states (it has offices in Minnesota and Ohio, but also covers dealflow in the Midwest and Pittsburgh). It also operates MedCityNews.com and a custom content service that creates made-to-order content for anyone that wants it. Its news content is syndicated throughthe Ohio News Network, Akron Beacon Journal, The Kindle, WKYC, the Boston online journal MassDevice and the Zemanta blog aggregator, among others.
Enforcer eCoaching
Seed Round in 2012
Enforcer eCoaching, Inc. is an email-based health coaching company based in Lyndhurst, Ohio, established in 2010. The company specializes in providing personalized wellness programs aimed at weight loss and diabetes management, among other health improvement needs. Its interactive programs are designed to foster enduring behavioral changes and improve participants' overall quality of life. By offering tailored daily advice and guidance, Enforcer eCoaching helps clients adopt effective health practices and achieve significant health transformations. The services are delivered through partnerships with health systems and healthcare plans, ensuring accessibility to a broad audience seeking to enhance their well-being.
Neuros Medical
Series B in 2012
Neuros Medical, Inc. is a neuromodulation company based in Willoughby Hills, Ohio, that specializes in developing proprietary neurostimulation therapies aimed at addressing unmet medical needs for patients globally. The company's flagship technology, known as Electrical Nerve Block, targets chronic pain conditions, including neuroma and residual limb pain, chronic post-surgical pain, and chronic migraine. Neuros Medical also offers the Neuros Altius System, which features an implantable generator with an integrated rechargeable battery, a cuff electrode, and associated external devices. Established in 2008, the company is dedicated to advancing innovative solutions for pain management.
Milo Biotechnology
Pre Seed Round in 2012
MILO BIOTECHNOLOGY Milo Biotechnology is a Cleveland-based company dedicated to improving the lives of patients with neuromuscular diseases. Milo's early clinical stage follistatin program, exclusively licensed from Nationwide Children's Hospital, is designed to increase muscle size and strength.
Anderson Aerospace
Seed Round in 2011
Anderson Aerospace, based in Kent, Ohio, specializes in the design and manufacture of advanced satellite antenna systems tailored for the aviation industry. Founded to explore opportunities in aerospace, advanced manufacturing, and satellite communications, the company boasts a team with over 140 years of combined experience in the sector. Their innovative antenna systems comply with the new ARINC antenna specifications for large fuselage-mounted designs, allowing clients to achieve significant reductions in weight and power consumption, while also lowering operational and installation costs.
Segmint
Venture Round in 2011
Segmint, Inc. is a data-driven technology company based in Cuyahoga Falls, Ohio, that specializes in providing customer insights through advanced data tagging, categorization, and contextualization. Founded in 2007, Segmint empowers financial institutions and fintech providers to effectively leverage customer data, enabling them to enhance customer interactions and measure marketing outcomes. The company's product suite includes Merchant Payment Cleansing, Transaction Analytics, and a Data-Driven Marketing Platform, along with solutions for competitor analysis, customer onboarding, and personalized marketing. Segmint's platform delivers targeted messages across various channels while adhering to privacy and security standards. With insights derived from billions of transactions, the company serves a diverse range of industries, including banking, retail, media, and insurance, helping organizations inform their strategies in competitive analysis, risk management, and product innovation.
CardioInsight Technologies
Series B in 2011
CardioInsight Technologies Inc. is a medical device company based in Cleveland, Ohio, that specializes in a non-invasive cardiac mapping system designed to visualize electrical disorders of the heart. The company's flagship product, ECVUE, utilizes an electrocardiographic mapping platform that combines body surface electrical data with anatomical information from CT scans to create simultaneous, multi-chamber, three-dimensional (3D) maps of cardiac electrical activity. The system employs a single-use, disposable multi-sensor vest to capture electrical signals from the body surface, which are then processed by software to produce detailed epicardial 3D electroanatomic maps and virtual electrograms. This innovative approach aids physicians in accurately diagnosing and treating heart conditions such as arrhythmias and congestive heart failure, a capability supported by over 260 patient studies. CardioInsight Technologies operates as a subsidiary of Medtronic plc, having been founded in 2006.
Thermalin
Series A in 2011
Thermalin, Inc. is a biotechnology company based in Cleveland, Ohio, founded in 2010, that specializes in developing innovative insulin therapies for individuals with Type 1 and Type 2 diabetes. The company aims to disrupt the insulin and insulin delivery market with its first-in-class, ultra-rapid acting insulin, which is stabilized and highly concentrated. This new insulin formulation is designed for use in a disposable, postage-stamp-sized glucose management system and can also be utilized in existing insulin pumps. In addition to its lead program, Thermalin is exploring partnerships to develop no-cold-chain basal and mix insulins, as well as glucose-responsive insulins. By creating insulin analogs that do not require refrigeration and are rapidly absorbed, Thermalin seeks to reduce the burden of insulin therapy, thereby improving patient adherence and health outcomes.
MedCity News
Seed Round in 2010
MedCity News creates content for people who care about health care. It is a solution for media companies and organizations that need content, stakeholders who need actionable information about the medical industry, and advertisers who want to speak to this valuable niche audience. Founded by veteran journalists with both health care reporting and online editorial experience, MedCity News is poised to build an innovative new-media enterprise capable of taking advantage of these converging forces while building a profitable national business and brand. It operates the MedCity News Service, a type of niche wire service focused on the innovation economies in major "medical cities" and states (it has offices in Minnesota and Ohio, but also covers dealflow in the Midwest and Pittsburgh). It also operates MedCityNews.com and a custom content service that creates made-to-order content for anyone that wants it. Its news content is syndicated throughthe Ohio News Network, Akron Beacon Journal, The Kindle, WKYC, the Boston online journal MassDevice and the Zemanta blog aggregator, among others.
Thermalin
Venture Round in 2010
Thermalin, Inc. is a biotechnology company based in Cleveland, Ohio, founded in 2010, that specializes in developing innovative insulin therapies for individuals with Type 1 and Type 2 diabetes. The company aims to disrupt the insulin and insulin delivery market with its first-in-class, ultra-rapid acting insulin, which is stabilized and highly concentrated. This new insulin formulation is designed for use in a disposable, postage-stamp-sized glucose management system and can also be utilized in existing insulin pumps. In addition to its lead program, Thermalin is exploring partnerships to develop no-cold-chain basal and mix insulins, as well as glucose-responsive insulins. By creating insulin analogs that do not require refrigeration and are rapidly absorbed, Thermalin seeks to reduce the burden of insulin therapy, thereby improving patient adherence and health outcomes.
TheraVasc
Series A in 2010
TheraVasc Inc. is a pharmaceutical and biotechnology company based in Cleveland, Ohio, that focuses on developing treatments for chronic medical diseases, particularly in the vascular disease market. Incorporated in 2009, the company specializes in repurposing drugs and offers TV1001, an oral formulation of sodium nitrite. This product is designed to improve blood flow and address conditions such as peripheral arterial disease and diabetic neuropathy, which significantly affect patients' quality of life. By targeting specific patient populations with poor blood circulation, TheraVasc aims to provide effective treatment options for underserved markets, promoting wound healing and preventing tissue necrosis in both humans and animals.
Laguna Pharmaceuticals
Seed Round in 2010
ChanRx Corp. intends to develop and market small molecule pharmaceuticals to treat atrial fibrillation, a common arrhythmia that can cause heart attacks and strokes. The company was founded in 2008 and is based in Cleveland, Ohio.
Echogen Power Systems
Series A in 2010
Echogen Power Systems, LLC specializes in developing heat-to-power generation systems that capture and convert waste heat into usable electricity. Founded in 2007 and based in Akron, Ohio, the company offers a range of heat recovery solutions suitable for applications such as gas turbines, industrial waste heat recovery, solar thermal, and geothermal energy, as well as hybrid alternatives to traditional internal combustion engines. Echogen's technology employs a carbon dioxide heat pump cycle to efficiently generate clean, renewable electricity, allowing businesses to monetize otherwise wasted heat and improve their overall energy investment returns. The company serves various industries that produce heat as a byproduct of their operations, helping to create reliable and emission-free energy options.
ABSMaterials
Series A in 2010
ABS Materials designs, develops, and delivers solutions for ground, surface, and municipal water contamination. Its solutions include VoC-Eater system, which destroys pharmaceuticals, chlorinated solvents, herbicides, endocrine disruptors, PCBs, dyes, and phenols to outflow clean water; Osorb, a solution to destroy persistent organic pollutants in the groundwater; and Iron-Osorb, an inert sand-like glass used on TCE/PCE/DCE/PCBs. The company’s solutions are used to clean solvents, pesticides, and other persistent organic pollutants from the water, soil, and air. It offers its systems on a rental and long term lease basis. The company was founded in 2008 and is based in Wooster, Ohio with an additional office in Houston, Texas.
Melody Management
Seed Round in 2010
Melody Management LLC, based in Columbus, Ohio, specializes in technology services designed to assist in the management of music careers. The company offers a central music management console that includes tools such as Melody Music Desk and Melody Card, which facilitate the distribution of music and streamline payment processes. Through its professional management tools, Melody Management enables artists to establish a consistent online presence and share essential content, including music, photos, videos, and news, to keep their fans engaged and informed.
TheraVasc
Seed Round in 2010
TheraVasc Inc. is a pharmaceutical and biotechnology company based in Cleveland, Ohio, that focuses on developing treatments for chronic medical diseases, particularly in the vascular disease market. Incorporated in 2009, the company specializes in repurposing drugs and offers TV1001, an oral formulation of sodium nitrite. This product is designed to improve blood flow and address conditions such as peripheral arterial disease and diabetic neuropathy, which significantly affect patients' quality of life. By targeting specific patient populations with poor blood circulation, TheraVasc aims to provide effective treatment options for underserved markets, promoting wound healing and preventing tissue necrosis in both humans and animals.
Electron Database
Seed Round in 2009
Electron Database Company (EDC) is a Cleveland, Ohio-based company building advanced software technology designed to dramatically improve the performance of enterprise applications, data warehouses and cloud computing infrastructures. EDC's patented technology is expected to deliver over 40 times faster performance on existing disk-based hardware versus existing database software and over 400 times faster performance on advanced, solid-state based hardware currently in development. Once released, EDC's technology will be the only database that fully leverages multi-core technology, 64-Bit computing, and solid-state memory drives that are expected to transform the hardware market and deliver material gains in energy efficiency.
Inspiron Logistics
Seed Round in 2009
Inspiron Logistics LLC specializes in developing and selling wireless emergency notification systems designed to facilitate effective communication during emergencies. Founded in 2003 and located in Cuyahoga Falls, Ohio, the company provides a technology that utilizes various communication methods, including text messaging, voice calls, email, and alerts from the National Oceanic and Atmospheric Administration (NOAA). This system enables clients, which include local governments, schools, colleges, businesses, and municipalities, to promptly send emergency alerts and information to users with profiles in their system. By integrating Geographic Information System (GIS) mapping, Inspiron Logistics enhances the capability of its clients to deliver mobile alerts to cellphones and connected devices, ensuring timely dissemination of critical information during emergency situations.
MAR Systems
Seed Round in 2008
MAR Systems, founded in 2006 and headquartered in Cleveland, Ohio, specializes in water purification technology that effectively removes metal contaminants such as mercury, selenium, and arsenic from water and industrial waste streams. The company has developed a patented process using Sorbster media technology, which assists clients in meeting stringent EPA standards by chemisorbing contaminants and providing a non-hazardous disposal solution. This innovative approach, co-developed with the EPA, is gaining traction as an industry standard, enabling clients to achieve efficient and cost-effective water purification.
Cervilenz
Seed Round in 2008
CerviLenz is a new, disposable device that measure vaginal cervical length during a speculum exam. Cervical length is a powerful predictor of preterm birth risk and influences patient management decisions. CerviLenz gives clinicians an immediate, reliable method for measuring the cervix at the point of care. CerviLenz is manufactured and distributed by Cervilenz Inc. headquartered in Chagrin Falls, Ohio.
CardioInsight Technologies
Series A in 2008
CardioInsight Technologies Inc. is a medical device company based in Cleveland, Ohio, that specializes in a non-invasive cardiac mapping system designed to visualize electrical disorders of the heart. The company's flagship product, ECVUE, utilizes an electrocardiographic mapping platform that combines body surface electrical data with anatomical information from CT scans to create simultaneous, multi-chamber, three-dimensional (3D) maps of cardiac electrical activity. The system employs a single-use, disposable multi-sensor vest to capture electrical signals from the body surface, which are then processed by software to produce detailed epicardial 3D electroanatomic maps and virtual electrograms. This innovative approach aids physicians in accurately diagnosing and treating heart conditions such as arrhythmias and congestive heart failure, a capability supported by over 260 patient studies. CardioInsight Technologies operates as a subsidiary of Medtronic plc, having been founded in 2006.
Inspiron Logistics
Venture Round in 2008
Inspiron Logistics LLC specializes in developing and selling wireless emergency notification systems designed to facilitate effective communication during emergencies. Founded in 2003 and located in Cuyahoga Falls, Ohio, the company provides a technology that utilizes various communication methods, including text messaging, voice calls, email, and alerts from the National Oceanic and Atmospheric Administration (NOAA). This system enables clients, which include local governments, schools, colleges, businesses, and municipalities, to promptly send emergency alerts and information to users with profiles in their system. By integrating Geographic Information System (GIS) mapping, Inspiron Logistics enhances the capability of its clients to deliver mobile alerts to cellphones and connected devices, ensuring timely dissemination of critical information during emergency situations.
Aria Analytics
Series B in 2007
Aria Analytics, Inc. develops and commercializes analytical technology to characterize liquids for healthcare and industrial applications. The company’s Aria technology is used for testing of raw materials, manufacturing process, contaminated products, counterfeit drugs and finished goods. Aria Analytics also offers subassembly systems and software for automated analytical diagnostics. It serves specialty chemical, healthcare, pharmaceuticals, and counterfeit product markets. The company was founded in 2003 and is based in Cleveland, Ohio. Aria Analytics, Inc. is a former subsidiary of 5iTech, LLC.
Echogen Power Systems
Seed Round in 2007
Echogen Power Systems, LLC specializes in developing heat-to-power generation systems that capture and convert waste heat into usable electricity. Founded in 2007 and based in Akron, Ohio, the company offers a range of heat recovery solutions suitable for applications such as gas turbines, industrial waste heat recovery, solar thermal, and geothermal energy, as well as hybrid alternatives to traditional internal combustion engines. Echogen's technology employs a carbon dioxide heat pump cycle to efficiently generate clean, renewable electricity, allowing businesses to monetize otherwise wasted heat and improve their overall energy investment returns. The company serves various industries that produce heat as a byproduct of their operations, helping to create reliable and emission-free energy options.
Logos Energy
Series A in 2007
Logos Energy is a mid-sized energy research organization based in Cleveland, Ohio.
Embrace Pet Insurance
Seed Round in 2007
Embrace Pet Insurance Agency LLC, based in Cleveland, Ohio, specializes in providing pet insurance services for dogs and cats across the United States. Founded in 2003, the company offers a range of insurance policies that cover unexpected accidents, genetic conditions, chronic illnesses, and various diagnostic tests, such as blood work, ultrasounds, and MRIs. Additionally, Embrace has developed Embrace360, a software application designed to help veterinary hospitals integrate pet insurance into their practices. The company aims to support pet owners in prioritizing their pets' health while maintaining their financial well-being. Embrace Pet Insurance Agency LLC operates as a subsidiary of Cleverland Holdings, LLC since 2019.
Telerad Express
Seed Round in 2007
Telerad Express provides remote daytime radiology interpretations in multiple modalities to imaging centers, hospitals, and medical practices. Telerad Express was founded in 2006 and is based in Beachwood, Ohio, United States.
Stanton Advanced Ceramics
Angel Round in 2007
Stanton Advanced Ceramics manufactures industrial ceramics that are used in heating and cooling applications such as in glass or steel making. The company offers proprietary thermally shock resistant, high temperature ceramic matrix composite (CMC) technologies. Stanton Advanced Ceramics was founded in 2001 and is based in Cleveland, Ohio.
Banyan Technology
Series B in 2007
Banyan Technology, Inc. is a provider of web-based logistics solutions that facilitate transportation management for manufacturers, distributors, and third-party logistics providers. Founded in 2000 and headquartered in Elyria, Ohio, Banyan offers a suite of tools designed to enhance freight management and improve operational efficiency. Its key offerings include Banyan Carrier Connect, which connects clients directly to their preferred carriers for profit and loss management, and Banyan Client Connect, aimed at helping third-party logistics providers retain and attract clients. Additionally, Banyan Digital Broker serves as a carrier sourcing tool for high-volume truckload shippers. By creating direct and instantaneous connections between clients and freight carriers, Banyan empowers over 27,000 businesses to make faster, more informed decisions regarding their freight operations, ultimately enhancing profitability and operational effectiveness. The company maintains a carrier-neutral approach, focusing on facilitating seamless communication between various business systems and stakeholders in the logistics sector.
Nine Iron Innovations
Seed Round in 2006
Nine Iron Innovations provides automated mobile video monitoring systems for golf course contests and events. The company’s product portfolio includes VerishotMobile, a golf shot video monitoring, contest, and marketing program for golf courses, event managers, golf management organizations, and independent representatives; and Sharegolf.com, a social networking site that connects golf courses and golfers, and allows them to view and share videos of their swings with other members. Nine Iron Innovations was founded in 2004 and is based in Ohio, United States.
FLX Micro
Venture Round in 2006
FLX Micro manufactures silicon carbide-based microsensors. The company develops its products through silicon carbide deposition and microfabrication technology platform. Its products are used in various applications, such as automotive, energy, environmental, and manufacturing. The company was formerly known as Fiberlead, Inc. FLX Micro, Inc. was founded in 2000 and is headquartered in Cleveland, Ohio.
HF Food Technologies
Seed Round in 2006
HF Food Technologies provides food technologies to enhance food flavor while minimizing fat content. The company’s product portfolio includes Nutrigras, a product that enables the one-to-one replacement of fat in beef, pork, and other related food products. This is addition to the seasonings, coatings, sauces and other food specialties they offer. HF Food Technologies operates retail stores in Chicago, Alabama, Georgia, South Carolina, and Tennessee, as well as an online store. The company was founded in 1981 and is headquartered in Cleveland, Ohio, Unites States.
Delta Plant Technologies
Seed Round in 2006
Delta Plant Technologies, Ltd. is a company based in Akron, Ohio, specializing in the production of ethanol as an alternative fuel source derived from the liquid byproduct of its natural rubber production. Established in 2003, the company focuses on developing innovative agronomics and processing technologies to enhance the production of both natural rubber and fuel ethanol feedstock in North America.
Embrace Pet Insurance
Seed Round in 2006
Embrace Pet Insurance Agency LLC, based in Cleveland, Ohio, specializes in providing pet insurance services for dogs and cats across the United States. Founded in 2003, the company offers a range of insurance policies that cover unexpected accidents, genetic conditions, chronic illnesses, and various diagnostic tests, such as blood work, ultrasounds, and MRIs. Additionally, Embrace has developed Embrace360, a software application designed to help veterinary hospitals integrate pet insurance into their practices. The company aims to support pet owners in prioritizing their pets' health while maintaining their financial well-being. Embrace Pet Insurance Agency LLC operates as a subsidiary of Cleverland Holdings, LLC since 2019.
Synapse Biomedical
Seed Round in 2006
Synapse Biomedical Inc. specializes in the research, development, and commercialization of neurostimulation products aimed at improving the lives of individuals with neurological impairments. Founded in 2002 and based in Oberlin, Ohio, the company has developed the NeuRx Diaphragm Pacing System, which utilizes a minimally invasive outpatient procedure to enhance breathing patterns. Additionally, Synapse Biomedical offers the TransAeris System, a temporary diaphragm stimulator designed for patients who are at risk of or require prolonged mechanical ventilation. These innovations are particularly beneficial for individuals suffering from conditions such as spinal cord injuries and amyotrophic lateral sclerosis (ALS), providing new treatment options that address the ventilatory needs of these patients. The company's advancements are rooted in over two decades of research conducted at Case Western Reserve University and the University Hospitals of Cleveland.
Knotice
Venture Round in 2006
Knotice is a direct digital marketing services and software company headquartered in Akron, Ohio that uses direct digital marketing to provide relevant marketing communications to consumers. Knotice maximizes the ROI of direct digital marketing through process automation, increased relevance, and improved performance. The company pioneered the concept of direct digital marketing – relevant digital communications that are addressed to individual recipients through an email address, Web browser cookie, or a mobile phone number, from a unified marketing database. Knotice’s on-demand software platform, Concentri®, offers simple, powerful ways to create and manage highly targeted, multi-stage communications across mobile, Web, and email. Concentri® is the only software that unifies the vital direct digital marketing channels of mobile, Web, and email. Concentri® provides onsite targeting, testing and optimization, email marketing, mobile marketing, landing page management, and universal profile management all from a unified environment.
Stanton Advanced Ceramics
Seed Round in 2005
Stanton Advanced Ceramics manufactures industrial ceramics that are used in heating and cooling applications such as in glass or steel making. The company offers proprietary thermally shock resistant, high temperature ceramic matrix composite (CMC) technologies. Stanton Advanced Ceramics was founded in 2001 and is based in Cleveland, Ohio.
Stanton Advanced Ceramics
Seed Round in 2004
Stanton Advanced Ceramics manufactures industrial ceramics that are used in heating and cooling applications such as in glass or steel making. The company offers proprietary thermally shock resistant, high temperature ceramic matrix composite (CMC) technologies. Stanton Advanced Ceramics was founded in 2001 and is based in Cleveland, Ohio.
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