Invest Detroit

CircNova is a biotechnology company that specializes in the development of non-coding RNA therapies aimed at addressing challenging disease targets. By leveraging artificial intelligence, CircNova generates, analyzes, and identifies circular RNA, which offers various mechanisms of action for therapeutic applications. The company's innovative approach focuses on harnessing the potential of circular RNA to create effective treatments for diseases that are traditionally considered undruggable.

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Treehouse is a venture-backed software-enabled home electrification startup focused on delivering turnkey EV charging solutions to EV buyers at the point of sale.

Voxel51, Inc., founded in 2016 and based in Ann Arbor, Michigan, specializes in computer vision and machine learning analytics for video and image understanding. The company develops AI software that transforms raw video footage and images into actionable intelligence, facilitating the exploration, visualization, curation, and testing of datasets alongside machine learning models. Voxel51's technology employs machine learning to process video content, providing simple image recognition and an understanding of motions and objects over time. This empowers computer vision data scientists to efficiently curate and experiment with their datasets, ultimately enhancing the performance of their machine learning systems.

SwishBx powers a revolutionary data-driven, product sampling marketplace to connect retailers and brands. With SwishBx, retailers enhance loyalty, strengthen supplier relationships and naturally expand their retail media offerings while seamlessly rewarding shoppers. For brands, SwishBx makes sponsored product sampling viable for all categories with self-serve, transparent, highly targeted and measurable technology that leverages first-party data to determine relevancy. SwishBx’s sponsored product sampling platform is available to online retailers and innovative brands of all sizes to deploy automated sampling campaigns which inspire incremental sales and expand lifetime customer value.

Opnr is an online platform that serves as a comprehensive marketplace for the entertainment industry, focusing on talent discovery and booking. It utilizes data-driven insights to streamline the process for both musicians and concert organizers. By providing relevant analytics, Opnr enables organizers to identify and book suitable artists for their events, while also assisting musicians in finding local performance opportunities. Additionally, the platform incorporates fanbase-influenced ticket sales, further enhancing its utility for both performers and event coordinators. Through its innovative approach, Opnr aims to reduce the time and friction typically associated with booking talent in the entertainment sector.

Treehouse is a venture-backed software-enabled home electrification startup focused on delivering turnkey EV charging solutions to EV buyers at the point of sale.

Judy Security is a cyber security company servicing small and medium businesses. The company's technology Judy uses a secure and private vault to create, store and protect all their passwords, keeping unauthorized users out of their login data.

Thread Medical operates an AI-based medical scribe platform designed specifically for ambulatory clinics, particularly in urgent care settings. The company's flagship product automates the creation of medical notes, capturing detailed data from patient encounters. This automation not only enhances the physician and patient experience but also supports precision medicine and billing tools, improving clinical decision-making and patient safety. By streamlining documentation processes, Thread Medical enables clinicians to save significant time—up to five hours per day—allowing them to focus more on patient care. Additionally, the structured data generated by the platform facilitates downstream automation and analytics, contributing to more efficient revenue cycle management in acute care environments.

CubeWorks Inc. specializes in developing millimeter-scale computing solutions, focusing on autonomous wireless sensing technology. Founded in 2013 and based in Ann Arbor, Michigan, the company has created the Cubisens platform, which includes ultra-small wireless smart sensors for various applications such as healthcare logistics, supply chain management, cold chain monitoring, security, and environmental monitoring. These sensors are characterized by their lightweight and durable design, making them suitable for deployment in challenging environments. By enabling real-time tracking and providing critical data access, CubeWorks aims to enhance the Internet of Things (IoT) landscape with innovative sensing solutions that address a wide range of monitoring needs.

Claira is an AI-powered competency analytics engine that assists organizations in understanding their talent and improving their hiring processes. Founded in 2020 and based in Grand Rapids, Michigan, Claira offers a platform that leverages a comprehensive dataset of competencies to provide insights into the current workforce, identify gaps, and analyze trends and future needs. This enables businesses to dynamically match resources and make informed decisions about their talent management strategies.

Plinqit provides smart savings app.

Judy Security is a cyber security company servicing small and medium businesses. The company's technology Judy uses a secure and private vault to create, store and protect all their passwords, keeping unauthorized users out of their login data.

Pocketnest is a financial planning platform that targets Generation X and millennials by providing comprehensive guidance on personal finances. The company employs a technology-driven approach grounded in psychology and behavioral science to create a tailored experience for users, covering all ten themes of personal finance. Its software is white-labeled for financial institutions such as banks, credit unions, investment advisors, insurance companies, and benefit providers. By utilizing Pocketnest's platform, these institutions gain access to valuable personal, behavioral, and financial data about their customers, enhancing their ability to serve a wider audience, identify cross-selling opportunities, and ultimately increase profitability. The platform is designed to guide users through systematic financial planning, resulting in actionable recommendations that promote financial wellness.

Ulendo provides software to improve the speed and accuracy of advanced manufacturing machines such as 3D printers and robots. The company's first product, Ulendo VC (vibration compensation), doubles the speed of extrusion-based 3D printers without sacrificing quality. Using its patented algorithm, Ulendo enhances a printer's firmware to anticipate vibration and change the tool path in order to avoid the quality issues that result from vibration. The company is also applying a similar vibration compensation approach to address vibration in industrial thereby enabling them to operate at faster speeds and with heavier payloads. This product, Ulendo VC-R, will be launched in 2025. The company recently launched Ulendo Calibration-as-a-ServiceTM, a hosted subscription-based software platform that calibrates an extrusion-based printer within seconds, thereby avoiding the current time-consuming practice of printing and measuring parts to determine the appropriate printing parameters. The company's third product, Ulendo HC (heat compensation), uses a patent-pending algorithm to optimize the laser path of a metal laser powder bed fusion (LPBF) printer to significantly reduce deformation and stress in the printed part.

InvestNext, founded in 2016 and based in Detroit, Michigan, focuses on transforming the way investment firms manage capital and engage with investors. The company developed an intuitive investment management platform that streamlines administrative processes and enhances investor relations. This platform offers features such as risk assessment, reporting, fundraising capabilities, and digitized client onboarding services, providing real-time insights that facilitate optimized decision-making. By fostering close partnerships with commercial real estate syndicators and investment firms globally, InvestNext aims to enhance transparency and efficiency in the investment management process. The platform is trusted by tens of thousands of investors, with billions of dollars managed, reflecting its impact on improving the investment experience and empowering firms to grow their businesses.

Traxen Inc. is a pioneering company at the forefront of innovative solutions in the transportation industry. Committed to revolutionizing the way we move goods, Traxen specializes in the development of cutting-edge technologies that optimize fleet management and enhance overall efficiency. Through a blend of advanced data analytics, artificial intelligence, and a deep understanding of logistics, Traxen strives to create intelligent solutions that not only improve operational performance but also contribute to a more sustainable and connected future in transportation. With a focus on safety, energy conservation, and smart mobility, Traxen Inc. is dedicated to shaping the next generation of transportation solutions for a rapidly evolving world.

86 Repairs is a Chicago-based software company that offers a subscription platform for managing the entire repair process for restaurant groups. Founded in 2018, the company provides a comprehensive maintenance management solution that covers equipment repairs for appliances such as ice machines, dishwashers, and ovens. With 24/7 support from a team of experts, 86 Repairs helps restaurant owners streamline their operations by relieving them of repair-related burdens, allowing them to concentrate on customer service. The platform delivers actionable insights to enhance back-of-house operations and ensures complete management of the service process, thereby improving efficiency and reducing downtime for restaurants.

Genomenon develops software tools to rapidly and autonomously prioritize data points for decision-making. It revolutionizes the way genetic diagnoses and discoveries are made. The company’s suite of diagnostic and discovery tools enable physicians, pharma, and researchers to quickly and accurately identify disease-causing variants from genomic-sequencing datasets. It was founded in 2014 and is headquartered in Ann Arbor, Michigan.

Asalyxa Bio, Inc. is a drug development company based in Southfield, Michigan, specializing in novel therapeutics aimed at addressing significant unmet medical needs resulting from the dysregulation of immune signaling. The company has developed a platform technology that facilitates the targeted delivery of both existing and innovative drugs directly into over-reactive immune cells. This approach is particularly focused on combating severe neutrophil-mediated diseases, including conditions such as Covid-19, and has applications across a broad range of disease areas. By leveraging this technology, Asalyxa Bio aims to enhance treatment options and improve patient outcomes in various therapeutic contexts.

Claira is an AI-powered competency analytics engine that assists organizations in understanding their talent and improving their hiring processes. Founded in 2020 and based in Grand Rapids, Michigan, Claira offers a platform that leverages a comprehensive dataset of competencies to provide insights into the current workforce, identify gaps, and analyze trends and future needs. This enables businesses to dynamically match resources and make informed decisions about their talent management strategies.

FlexTal is a talent matching platform that connects companies with experts for various projects, utilizing artificial intelligence to streamline the sourcing, vetting, and engagement process. The platform offers access to a curated network of elite professionals across multiple fields, including business, sales, marketing, finance, design, and technology. By enabling companies to engage top-tier independent contractors on an hourly, part-time, full-time, or project basis, FlexTal enhances operational efficiency and agility in a rapidly changing workforce landscape. The company has experienced significant growth and aims to democratize access to specialized talent, facilitating improved productivity, efficiency, and overall quality of work life for both businesses and professionals. As the nature of work evolves alongside advancements in digital transformation and automation, FlexTal positions itself as a vital resource for organizations seeking to adapt to new workforce dynamics.

Auralab Technologies is customized in the development of innovative technologies to promote deep Slow Breathing, a clinically validated practice that reduces anxiety and promotes wellness. AuraLab has been instrumental in bringing the core algorithm to the iPhone, as well as taking on both front and backend software development, in addition to participating in the company's strategy development.

ToDooly is a social platform that connects community members with local students to assist with everyday tasks. Founded in 2017 and based in Grosse Pointe Park, Michigan, the platform allows users to hire students for simple outdoor jobs at a rate of $20 per hour, plus a $5 booking fee. The services offered focus on basic household tasks such as yard work and routine cleaning, but do not include specialized services that require professional expertise. By leveraging the availability of college students, ToDooly aims to make it easier for busy individuals to manage their to-do lists effectively.

Airspace Link digitizes local airspace for urban air mobility. It provides government, citizen, and business drone solutions to support local government airspace management, fostering citizen empowerment, and business innovation through consumer and b2b air logistical support and services. It was founded in 2018 and is based in Detroit, Michigan.

Alerje, Inc. is a company based in Detroit, Michigan, specializing in emergency medicine and digital oral immunotherapy management for individuals with food allergies. Founded in 2015, Alerje has developed an innovative epinephrine auto-injector designed to fit within a smartphone case, enhancing patient adherence and emergency response capabilities. The accompanying mobile application allows users to create personalized food allergy profiles, share this information with their CareCircle—comprising family, friends, caregivers, and medical professionals—and receive location alerts. Additionally, the platform enables users to filter recipes and scan grocery items for potential allergens, thereby improving dietary decision-making. Alerje's system has been validated by the National Science Foundation, emphasizing its commitment to enhancing the quality of life for those affected by food allergies.

Orbion Space Technology, based in Houghton, Michigan, specializes in the development and manufacture of plasma propulsion systems for small satellites. Founded in 2016, the company provides advanced electric propulsion technology that enhances satellite functionality by enabling precise maneuverability in space. Orbion's thrusters facilitate essential tasks such as the last-mile delivery of spacecraft from launch vehicles to their designated orbits, extending the operational life of satellites, and ensuring safe de-orbiting at the end of their missions. By offering a cost-effective solution that can significantly reduce operational expenses for spacecraft operators, Orbion contributes to the growing demand for efficient propulsion systems in the rapidly evolving space industry.

Alerje, Inc. is a company based in Detroit, Michigan, specializing in emergency medicine and digital oral immunotherapy management for individuals with food allergies. Founded in 2015, Alerje has developed an innovative epinephrine auto-injector designed to fit within a smartphone case, enhancing patient adherence and emergency response capabilities. The accompanying mobile application allows users to create personalized food allergy profiles, share this information with their CareCircle—comprising family, friends, caregivers, and medical professionals—and receive location alerts. Additionally, the platform enables users to filter recipes and scan grocery items for potential allergens, thereby improving dietary decision-making. Alerje's system has been validated by the National Science Foundation, emphasizing its commitment to enhancing the quality of life for those affected by food allergies.

86 Repairs is a Chicago-based software company that offers a subscription platform for managing the entire repair process for restaurant groups. Founded in 2018, the company provides a comprehensive maintenance management solution that covers equipment repairs for appliances such as ice machines, dishwashers, and ovens. With 24/7 support from a team of experts, 86 Repairs helps restaurant owners streamline their operations by relieving them of repair-related burdens, allowing them to concentrate on customer service. The platform delivers actionable insights to enhance back-of-house operations and ensures complete management of the service process, thereby improving efficiency and reducing downtime for restaurants.

GreenMark Biomedical Inc. is a healthcare company focused on developing minimally invasive technologies utilizing biopolymer nanoparticles derived from natural starch. Founded in 2016 and based in East Lansing, Michigan, with a laboratory in Ann Arbor, the company aims to enhance diagnostic and treatment capabilities in dentistry and oncology. GreenMark offers a mouth rinse product that highlights cavities and early-stage lesions, allowing dentists to accurately assess dental issues using standard dental curing lamps. Additionally, the company is working on medical applications that target anti-cancer drug delivery, facilitating site-specific treatments. Through its innovative approach, GreenMark Biomedical seeks to provide effective health-based solutions that improve patient care.

SpellBound is a company based in Ann Arbor, Michigan, that specializes in providing immersive augmented reality tools aimed at enhancing the experience of pediatric patients undergoing medical treatment. Founded in 2015, SpellBound's platform leverages existing iOS and Android devices used by hospital staff and families to bring educational content, such as books and printed materials, to life in three dimensions. This technology is designed to assist children in coping with medical procedures by offering procedural support that helps manage acute pain and improves patient education. By transforming the hospital environment digitally, SpellBound enables therapists to reduce trauma for young patients while also lowering costs for healthcare facilities.

Bloomscape, Inc. is an online retailer based in Detroit, Michigan, specializing in the sale of houseplants and related care tools. Founded in 2017, the company provides customers with a variety of fully grown potted plants, including popular species such as tradescantia zebriana, pinstripe, and spider plants. Bloomscape focuses on enhancing the plant-buying experience by delivering ready-to-go plants directly to customers' doors, along with essential post-purchase care instructions. Additionally, the company offers a Plant Mom service, allowing customers to seek expert advice on plant care. Bloomscape aims to foster strong relationships between customers and their plants, simplifying the process of purchasing and maintaining indoor greenery.

Mi Padrino is an event planning service tailored for the Hispanic community, assisting families in organizing, planning, and funding significant cultural celebrations such as Quinceañeras, weddings, and baptisms. Founded by Kim Gamez, who recognized the complexities involved in coordinating these traditional events, Mi Padrino offers an innovative platform that simplifies the process. The service allows users to manage event details and share them with friends and family worldwide, ensuring that loved ones can participate in celebrations regardless of their location. Additionally, the platform facilitates the acceptance of funds from sponsors, making financial contributions more accessible and efficient. Overall, Mi Padrino provides a comprehensive solution for families to honor their traditions while embracing modern technology.

Ripple Science Corporation specializes in developing web-based software aimed at enhancing the recruitment and management of participants in clinical, translational, and social science studies. Founded in 2016 and headquartered in Ann Arbor, Michigan, the company offers solutions that streamline various aspects of the research process, including participant tracking, recruitment campaign management, and task management. Ripple Science's flagship product, Ripple SaaS, leverages sales and marketing automation tools to expedite participant recruitment, significantly benefiting academic researchers and clinical trial sites. Currently, its software is utilized by over 75 academic and research centers globally, including prestigious institutions such as Johns Hopkins University and the University of California, Los Angeles. By addressing the challenges of patient recruitment and engagement, Ripple Science enables researchers to enhance communication and collaboration, leading to more efficient study operations and quicker completion times.

Shoptelligence Inc. is a company based in Ann Arbor, Michigan, that operates an AI-powered style discovery platform designed to enhance the shopping experience for customers and drive sales for retailers. Founded in 2018, the platform utilizes an AI Style Assistant to curate product collections based on individual style preferences, enabling shoppers to discover new items across a retailer's entire catalog. The platform includes features such as virtual sales assistants, email marketing tools, and customer style curation, which collectively aim to increase customer engagement, retention, and average order value. By providing a personalized shopping experience, Shoptelligence helps retailers foster customer loyalty and boost revenue.

PawnGuru has set out to revolutionize the way 30 million US consumers interact with the growing pawnshop industry. By creating a harmonious marketplace for consumers and local shops to interact, PawnGuru aims to bring the 10+ billion dollar pawnshop industry online.

Workit Health, Inc. is a provider of online therapeutic content and professional counseling services focused on substance use recovery. Established in 2014 and based in Ann Arbor, Michigan, the company operates the Workit platform, which offers clinically proven telemedicine treatment for substance use disorder, including online therapy, medication-assisted treatment, psychiatric support, and primary care. Workit Health's services are designed to help individuals achieve long-term recovery from drugs and alcohol while minimizing disruption to their daily lives. The platform facilitates access to on-demand, in-person, and virtual medical and psychosocial support, catering to a wide range of clients including employers, educational institutions, healthcare facilities, and recovery communities. Additionally, Workit Health provides accredited opioid addiction treatment featuring buprenorphine, enhancing its commitment to harm reduction in addiction care. The company has locations in California, New Jersey, Alaska, and Washington.

Sportsman Tracker is a cross-platform digital toolset designed to increase success opportunities for hunters and fishermen and allow them to quickly share their experiences. Powered by W.I.T. (Wild Life Intelligence Technology), the tracker calculates the variables that directly affect wildlife behavior. The platform lets track species and gets adaptive features that are specific only the species. Founded in 2012 by Jon Schwander and Jeffrey James Courter, Sportsman Tracker is headquartered in Grand Rapids, Michigan.

Genomenon develops software tools to rapidly and autonomously prioritize data points for decision-making. It revolutionizes the way genetic diagnoses and discoveries are made. The company’s suite of diagnostic and discovery tools enable physicians, pharma, and researchers to quickly and accurately identify disease-causing variants from genomic-sequencing datasets. It was founded in 2014 and is headquartered in Ann Arbor, Michigan.

VNN, Inc. operates a leading high school sports marketing and networking platform that enables athletes to share videos, pictures, stories, and scores via various digital devices. The platform also allows coaches to report game results to media outlets, enhancing the visibility of high school sports. Serving schools across more than 40 states, VNN has established itself as the largest and fastest-growing entity in the high school sports marketing sector, connecting over seven million fans and adding thousands of new users daily. Founded in 2010 and based in Grand Rapids, Michigan, VNN is dedicated to transforming the consumer experience in the multi-billion dollar high school sports market.

Akadeum Life Sciences, Inc. is a life sciences company based in Ann Arbor, Michigan, founded in 2014. The company specializes in manufacturing microbubble cell separation products designed to facilitate the removal of target cells from biological samples. Its product line includes T cell and B cell isolation kits for both human and mouse cells, as well as products for red blood cell depletion. Akadeum utilizes buoyancy-activated cell sorting technology, employing microscopic microbubbles that capture target cells and float them to the surface for efficient removal. This innovative approach enhances the efficiency of downstream testing and analysis for medical practitioners. The company's products are available for purchase online, and it maintains a strategic partnership with Agilent Technologies.

ardentCause provides online solutions for using data, to achieve better outcomes, to foundations, funders, nonprofits, collaborations and schools.Outcomes and Impact – Data collection, analysis and visualization across multiple programs can help you gauge your community impact. Visual Knowledge for Nonprofits – Use data you have for informed decision making. Nonprofit Collaboration Dashboard – Share Information across the collaborative. Self Sufficiency Matrices (SSM) – Collective impact using SSM data of any type across your community! Online Client, Activity and Asset Tracking. MatrixPath: Outcomes Assessment Matrices – Data entry and management solutions. LiteracyPath: Adult Literacy – Client and activity tracking with robust reporting functionality. Education Solutions - Collects separated student data into ONE easy to access location, automatic alerts and indicator formulas for student performance; school and district dashboards that help visualize performance trends for improved communication and decision making.

PawnGuru has set out to revolutionize the way 30 million US consumers interact with the growing pawnshop industry. By creating a harmonious marketplace for consumers and local shops to interact, PawnGuru aims to bring the 10+ billion dollar pawnshop industry online.

PeachWorks Inc. is a cloud-based software provider focused on the restaurant, hospitality, and retail industries. Founded in 2005 and based in Southfield, Michigan, the company offers a suite of tools that facilitate employee scheduling, inventory management, reporting, and recipe management. By streamlining these essential functions, PeachWorks enables businesses to address operational challenges effectively, enhance efficiency, and boost profitability. Originally known as WhenToManage Inc., the company rebranded to PeachWorks in March 2015 and has been operating as a subsidiary of Beyond since April 2018.

Sportsman Tracker is a cross-platform digital toolset designed to increase success opportunities for hunters and fishermen and allow them to quickly share their experiences. Powered by W.I.T. (Wild Life Intelligence Technology), the tracker calculates the variables that directly affect wildlife behavior. The platform lets track species and gets adaptive features that are specific only the species. Founded in 2012 by Jon Schwander and Jeffrey James Courter, Sportsman Tracker is headquartered in Grand Rapids, Michigan.

Tome is a tech company that develops connectivity products to keep people and mobiles active, and creates value as a focused niche within the larger Internet of Things movement. It was created as the result of a passion for connecting hardware products to software applications. Tome was founded in 2014 by Jake Sigal and Massimo Baldini. It is based in Royal Oak, M.I. Tome is a member of the StartUp Health accelerator, based in New York City.

American Mountain Co. specializes in high-quality mountain wear, offering a range of apparel designed for both performance and style. Their product line includes jackets, sweaters, t-shirts, and hand gloves, all meticulously crafted to ensure optimal functionality without compromising on aesthetic appeal. The company is dedicated to delivering durable and versatile outdoor clothing that meets the demands of mountainous environments while maintaining a classic style.

TurtleCell is a mobile accessories company that specializes in innovative protective cases for popular smartphones. Its flagship product features a unique design that incorporates retractable earbuds stored within the case, allowing users to keep their headphones secure and untangled while providing essential protection for their devices. This proprietary mechanism enables the storage of a full-length headphone cord within a case that is thinner than typical external battery cases, offering both functionality and style. TurtleCell aims to address common issues faced by smartphone users, such as losing or damaging their headphones, while delivering an effective and aesthetically pleasing solution.

Livio Radio, operating under Myine Electronics, LLC, specializes in designing and manufacturing electronic audio products. Founded in 2008 and based in Ferndale, Michigan, the company offers a range of Bluetooth Internet radio car kits compatible with iPhones and Android devices, as well as car audio players tailored for both personal and commercial use. In addition to its hardware offerings, Livio Radio provides the Livio Connect API, a middleware framework that facilitates the connection and interaction between hardware and various mobile applications. Its products are distributed through retailers, resellers, and online platforms, ensuring accessibility for a wide audience.

MI Bioresearch is a specialty contract research organization (CRO) providing in vivo preclinical imaging services. With a proven track record of imaging and drug discovery expertise, the company enhances preclinical and translational research through its in vivo pharmaco-IMAGING platform. This combination of traditional pharmacology and innovative imaging includes MRI, micro-CT, micro-PET, SPECT and optical (bioluminescence and fluorescence molecular tomography) tools to quantitatively measure the response to therapy at anatomical, functional and molecular levels. Molecular Imaging also provides supportive in vitro services. They have performed over 2000 cell line based traditional oncology studies and over 500 imaging enhanced studies since their founding in 2003.