IndieBio

Fermeate is a stealth-mode biotechnology company that specializes in photomolecular fermentation technology. This innovative approach aims to enhance sustainability and efficiency within the biomanufacturing industry.

Materia Bioworks is a pioneering company that develops data-driven informatics tools to facilitate the creation and adoption of sustainable biomaterials. Their AI-powered platform streamlines the process of developing and manufacturing biomaterial products, from sourcing materials to final production. This enables material scientists, product developers, suppliers, and converters to accelerate and enhance their work in biomaterial applications, fostering a more sustainable future across various industries.

Prellis Biologics, Inc. is a biotechnology company based in San Francisco, California, that specializes in bioprinting human tissues for drug development and organ transplantation. Founded in 2016, the company focuses on overcoming the challenges of creating vascularized human tissues and organs, aiming to revolutionize healthcare. Its innovative technology allows for the precise engineering of human tissues, including lymph node organoids, which can replicate human immune responses for various applications such as antibody discovery and tumor-immune modeling. Prellis Biologics offers a range of products, including TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X, which collectively enhance early-stage drug discovery and translational pharmacology.

Particella is a biotechnology company that specializes in developing a proprietary oral lipid nanoparticle technology designed to deliver mRNA and other nucleic acids. This innovative approach aims to transform the administration of biological medicines by utilizing the intestinal tract to facilitate the secretion of proteins into the bloodstream. By enabling the oral delivery of protein biologics, Particella's technology seeks to address the limitations of current methods, ultimately allowing healthcare providers to prevent gastrointestinal diseases in patients more effectively. The company's advancements hold the potential to create a new category of medicines, enhancing the accessibility and efficacy of treatments.

Ten63 Therapeutics, Inc. is a biotechnology company based in Chapel Hill, North Carolina, focused on developing potent therapeutics for medically validated yet undruggable targets. Founded in 2017, the company utilizes its innovative platform, COPPER, which combines machine learning-based computational chemistry with advanced physical modeling to explore an extensive chemical space. This approach allows Ten63 Therapeutics to discover novel drug candidates for some of the most lethal diseases by employing proprietary algorithms for scaffold redesign and optimizing chemical design. By integrating these technologies, the company aims to produce durable therapies and improve drug resistance prediction, ultimately addressing challenges in drug development for previously intractable targets.

Giraffe Bio specializes in developing biomolecular technology to enhance the efficiency and sustainability of critical mineral extraction. Their platform tailors biomolecules to the specific geology of each mine, boosting metal recovery, reducing water usage, and minimizing environmental impact. This is achieved by integrating biology, artificial intelligence, and hardware to optimize extraction processes, enabling clients to improve recovery rates and reduce extraction times.

AlkaLi Labs is a biotechnology research company founded in 2023 and based in San Francisco, California. The company focuses on developing biological solutions to unlock domestic mineral resources. Currently operating in stealth mode, AlkaLi Labs aims to innovate in the field of biotechnology by leveraging natural processes to enhance resource extraction and sustainability.

Unlocked Labs specializes in the development of genetically optimized probiotics aimed at addressing chronic health conditions. The company focuses on activating dormant microbial abilities within a safe and established framework. Its rigorously tested probiotic strains are specifically designed to target and eliminate harmful compounds in the gastrointestinal tract. Unlocked Labs' inaugural product is formulated to reduce the risk of kidney stones by digesting stone-forming compounds that may be ingested from healthy foods, such as leafy vegetables. By utilizing alternative regulatory pathways, the company seeks to expedite the availability of safe and effective probiotic solutions for consumers, enabling them to detoxify their bodies and manage acid levels affordably and effectively.

BioLattice is a biotechnology company focused on developing tissue-engineered cornea technology. Their primary goal is to provide a viable alternative to donor tissue for full-thickness corneal transplants. The company's innovative technology offers a corneal prototype with vision-correcting capabilities, aiming to restore sight for patients requiring corneal transplants.

Vitarka Therapeutics is a London-based company that specializes in developing medical technologies and solutions aimed at treating various types of cancer. The company has created a targeted non-viral delivery platform designed for intracellular targets, particularly in oncology, neuroscience, and neurodegeneration. This innovative platform works by activating the immune system and normalizing tumor vasculature, significantly improving outcomes for late-stage cancer patients, including those with lung, colon, and breast cancers. By utilizing re-engineered pore-forming proteins, Vitarka Therapeutics enables cell-specific targeting and endosomal release of therapeutic cargo, providing cancer patients with improved prospects for leading normal lives and maintaining hope for the future.

ViAn Therapeutics is an early-stage biotechnology company dedicated to innovating treatments for retinal diseases. The company is developing a first-in-class, non-invasive eyedrop treatment aimed at replacing traditional invasive injections for conditions such as age-related macular degeneration and diabetic macular edema. With robust preclinical data and ongoing clinical testing, ViAn is poised to address significant unmet medical needs within the retinal disease sector, which represents a substantial market opportunity. In addition to its focus on ophthalmology, ViAn is also engaged in creating peptide drugs designed to inhibit angiogenesis, potentially benefiting patients suffering from cancer and other angiogenesis-dependent diseases. Through its innovative approaches, ViAn Therapeutics seeks to enhance patient outcomes and improve the overall quality of life for individuals affected by these conditions.

Asterix Foods is a biotechnology company based in Tel Aviv, Israel, founded in 2022. The company specializes in developing protein production through plant-cell culture techniques, focusing on the creation of bioactive proteins for food applications. Asterix Foods aims to provide scalable, functional, and complex proteins that are derived from plant cell cultures, offering an animal-free alternative for consumers.

Sun Genomics, Inc. is a microbiome health company based in San Diego, California, specializing in customized probiotics aimed at addressing dysbiosis. Founded in 2014, the company’s flagship product, Floré, combines a gut microbiome test with personalized probiotic formulations tailored to individual gut profiles, assessed through whole-genome sequencing. The Floré Gut Test includes a microflora collection kit, a comprehensive microflora profile analysis, and wellness consultations. Additionally, Sun Genomics offers Floré Tots, a probiotic solution designed for children up to age 12, which comes in a convenient powder form that can be easily mixed with beverages. The company sells its products online, providing an automatic renewal service to enhance customer convenience.

Capra Biosciences is a biotechnology company focused on the sustainable and efficient production of everyday chemicals through innovative bioreactor technology. The company has developed a biofilm bioreactor that aims to streamline the bio-manufacturing process, effectively reducing downstream processing requirements and associated costs. This technology not only enhances the production efficiency of bio-based chemicals but also enables the creation of hydrophobic products, including retinol and performance lubricants. By harnessing biological processes, Capra Biosciences contributes to a low-carbon future while addressing the growing demand for sustainable chemical solutions.

Synplexity is a biotechnology company located in New Castle, Delaware, specializing in mutational scanning and multiplexed gene synthesis through advanced artificial intelligence technology. The company operates a large-scale gene synthesis and proteomics discovery platform that utilizes microdroplets as microreactors. This innovative approach allows for the efficient creation of multiplex gene libraries, which have applications across various sectors, including therapeutics, biomanufacturing, agriculture, and climate systems. Synplexity aims to drive advancements in healthcare and other industries through its cutting-edge genetic technologies.

Laguna Bio is a biotechnology company focused on cancer treatment through its innovative drug discovery platform. Founded in 2022 and headquartered in Berkeley, California, the company specializes in selectively activating and expanding the innate immune system to combat solid tumors. By enhancing the response rate of bispecific antibody drugs, Laguna Bio aims to provide specific T cells that strengthen the immune system's ability to fight cancer, ultimately improving survival rates for patients facing this deadly disease.

FREZENT is a biotechnology company focused on developing innovative therapeutics for advanced-stage cancer patients. It specializes in creating biological inhibitors that target cancer-specific lipid metabolism, aiming to prevent the reactivation of dormant cancer cells.

NanoPlume is a biomaterial manufacturer specializing in the large-scale production of innovative, eco-friendly biomaterials, notably Bio-Aerogel. The company focuses on creating advanced insulating biomaterials and aerogels, aiming to enhance energy and space efficiency, as well as promote circularity across various industries. By utilizing organic and recycled feedstocks and green technology, NanoPlume reduces waste and minimizes energy consumption. Its products are designed to insulate cargo boxes in the cold chain healthcare logistics sector, reducing payload and energy consumption, and extending battery range.

DisperseBio is a Biotechnology Research firm developing a mechanism to counter microbial contamination on natural surfaces like human body.

Huue is a company specializing in sustainable dyeing solutions for the fashion and textile industries, particularly focusing on the denim supply chain. It employs innovative biotechnology to produce bio-synthesized dyes through a fermentation process involving naturally occurring microorganisms. This method not only eliminates the need for toxic chemicals traditionally used in dye production but also utilizes renewable resources, making it an eco-friendly alternative. By offering greener options for color production, Huue aims to support the industry's transition towards more sustainable practices, ultimately contributing to a more environmentally responsible approach to fashion.

Mothership Materials specializes in converting agricultural waste into valuable biomolecules using its proprietary Targeted Molecular Recovery (TMR) technology. The company's process efficiently extracts proteins, lipids, antioxidants, sugars, and cellulose from waste streams, enabling agricultural producers and waste managers to create a circular economy and maximize waste value.

Gatehouse Bio is a biotech company based in Waltham, Massachusetts, founded in 2016. The company specializes in the development of therapies utilizing a novel bioinformatics platform that focuses on small ribonucleic acid (RNA) biomarkers. This platform is designed to classify patient samples with binary accuracy and identifies disease-associated mutations, enabling the creation of targeted therapeutics. By employing artificial intelligence, Gatehouse Bio aims to analyze small RNA genes and design oligonucleotides that can effectively counteract the effects of these mutations. Their research and development efforts target therapeutic areas with known heterogeneity, such as fibrosis, inflammation, and neurodegeneration, with the goal of unlocking the potential for improved patient outcomes through personalized medicine.

Sóliome is a biotechnology company based in San Francisco, California, founded in 2021. The company specializes in the development of protein-based sunscreens designed to be safe for both human use and the environment. Sóliome's innovative products aim to reduce the absorption of harmful chemicals found in traditional sunscreens, which can contribute to skin inflammation and ecological damage. By focusing on skin protection from harmful rays while minimizing environmental impact, Sóliome addresses growing concerns about both personal health and sustainability in skincare.

Minutia is a biotechnology company focused on developing innovative stem cell-derived transplants aimed at treating Type 1 Diabetes. The company specializes in creating insulin-producing cell transplants that incorporate proprietary nanosensors, allowing for real-time monitoring of transplant status. These immune-evasive cells are designed for subcutaneous implantation, addressing common challenges associated with transplant procedures. By advancing this technology, Minutia seeks to transform the clinical landscape for diabetes management and cell replacement therapies, ultimately working towards a functional cure for this condition.

Calyx specializes in developing advanced sensor technology focused on monitoring environmental parameters, particularly in the poultry and livestock sectors. The company integrates artificial intelligence, computer vision, and bio-engineered sensors to create versatile platforms capable of detecting airborne chemical emissions with high specificity and sensitivity. Its innovative sensors are designed using patterned viruses that bind to specific gas molecules, allowing for accurate detection of various airborne chemicals. This technology not only addresses complex challenges in livestock management but also enables commercial customers to monitor and respond to daily environmental health changes effectively.

Asta Bio is a biotechnology company specializing in the development of radiotherapeutics for cancer treatment. It focuses on combining the alpha-emitting radioisotope 211-Astatine with multivalent single-domain antibodies to deliver targeted alpha radiation to tumor cells, sparing healthy cells. This approach aims to effectively destroy cancer cells by breaking their DNA strands.

DNAzyme is a biotechnology company specializing in the development of enzymes derived from Antarctic extremophile microorganisms as active ingredients for skin health applications. Utilizing recombinant DNA repair technology, the company produces highly pure enzymes at an industrial scale, enabling clinicians to create innovative solutions for skin health and rejuvenation in both the cosmetic and pharmaceutical industries.

Tinkeso Therapeutics is a biotechnology company specializing in the development of innovative, off-the-shelf cell therapies for treating cancer and autoimmune diseases. The company focuses on creating allogeneic chimeric antigen receptor (CAR) engineered natural killer T (NKT) cell therapies, which use NKT cells to target and destroy cancer cells or modulate the immune response in autoimmune conditions. This approach aims to increase treatment accessibility and scalability by utilizing non-patient-specific cells.

heXem bio specializes in recording solutions for the early development of humans for longevity.

BugBiome is a biotechnology company that develops eco-friendly bio-repellents to create natural pest control products. It focuses on identifying and enhancing beneficial microbes that deter pests organically, providing an alternative to traditional chemical methods. The company aims to minimize environmental impact and promote sustainable pest management practices, potentially benefiting sectors such as agriculture and households.

Restoring crops' ability to defend against pests.

Fermeate is a stealth-mode biotechnology company that specializes in photomolecular fermentation technology. This innovative approach aims to enhance sustainability and efficiency within the biomanufacturing industry.

Oobli is a food company focused on developing innovative protein sweeteners derived from exotic plants. These unique sweeteners offer a delicious taste while significantly reducing calories, making them a healthier alternative to traditional sugars. Produced through fermentation, Oobli's sweeteners have no glycemic impact and do not influence the gut microbiome, allowing consumers to enjoy sweetness without concerns related to blood sugar, insulin, or weight management. The company has successfully obtained regulatory approvals, including FDA "no questions" letters and GRAS status for multiple protein sources, which positions it as a leader in the healthy sweetener market. By transforming flavors, Oobli aims to enhance everyday food experiences while promoting better health outcomes for its users.

CellCrine focuses on discovering enzymes that transform cell culture for the cell-based meats industry. CellCrine was founded in 2021and was headquartered in United, States.

Transition Biomining is a technology-focused company specializing in copper ore mining. It employs data-driven methods to enhance copper extraction and mining efficiency. The company's core innovation lies in optimizing microbial communities for heap-leaching operations, aiming to boost metal recovery rates, expedite extraction, and minimize environmental impact. By harnessing the power of microbiomes, Transition Biomining provides sustainable and data-driven solutions to improve clients' extraction processes in both new and existing heap-leaching operations.

MycoWorks is a biotech company that specializes in producing sustainable materials derived from mycelium, the root structure of fungi. By utilizing this natural resource, MycoWorks offers innovative alternatives to conventional plastic foams, synthetic textiles, and leather. Their products are designed to be energy-efficient and biodegradable, catering to various industries, including aerospace, automotive, apparel, and architectural interiors. Through a carbon-negative process, the company transforms agricultural byproducts and mycelium into high-quality materials, allowing clients to access rapidly grown, eco-friendly leather substitutes. MycoWorks aims to address environmental concerns associated with traditional materials while promoting the use of bio-based solutions.

OncoPrecision is a biotechnology company focused on enhancing cancer treatment through its innovative patient micro avatar platform. This platform utilizes single-cell high-throughput biology and advanced machine learning techniques to develop comprehensive patient-derived phenotypic biomarkers. By tailoring cancer therapies to individual patients, OncoPrecision aims to significantly increase the success rates of treatments. The company's approach enables oncologists to make informed, data-driven decisions regarding therapy selection based on unique patient samples, thereby improving outcomes in cancer care.

BugBiome is a biotechnology company that develops eco-friendly bio-repellents to create natural pest control products. It focuses on identifying and enhancing beneficial microbes that deter pests organically, providing an alternative to traditional chemical methods. The company aims to minimize environmental impact and promote sustainable pest management practices, potentially benefiting sectors such as agriculture and households.

Avalo is a plant biology company that employs interpretable machine learning, genomic discovery, and evolutionary theory to expedite the development of new crops tailored for future agricultural needs. Utilizing AI-assisted plant breeding methods, Avalo creates non-GMO products that foster natural biodiversity. Its core technology, a discovery engine, can swiftly identify genetic bases of complex traits even in understudied crops, reducing time and cost significantly compared to traditional methods. This enables Avalo to forecast and enhance crop traits like drought tolerance and nutrient density, adapting agriculture to changing climates.

HelEx is a biotechnology company founded in 2021 and based in New York, specializing in genomic medicines tailored for renal indications. The company utilizes its proprietary genomics data and bioinformatics to develop, validate, and distribute therapy-specific guide RNAs (gRNAs). HelEx's innovative platform leverages data-driven deep-learning modeling, utilizing high-throughput next-generation sequencing data derived from CRISPR edits on human cell lines. This approach provides reliable predictions and allows for in-house validation, thereby facilitating the acceleration of drug discovery and the development of cell and gene therapies in the CRISPR-based market.

Calder Biosciences is a biotechnology company focused on developing advanced vaccines to combat life-threatening viruses. Recognizing that traditional vaccines often fail to provide adequate protection against evolving viral threats, Calder employs its proprietary 3D-Vaxlock technology, which utilizes structure-based design to enhance the stability and efficacy of vaccine candidates. This innovative platform creates molecular staples that maintain vaccines in their most effective configurations, addressing the common shortcomings of subunit vaccines, such as limited potency and shelf-life. Calder's current projects include a universal flu vaccine aimed at covering all seasonal strains and a respiratory syncytial virus (RSV) vaccine tailored for the elderly. By prioritizing the development of vaccines with exceptional safety, efficacy, and durability, Calder aims to reduce severe disease and mortality rates while alleviating the burden on healthcare systems, ultimately contributing to healthier lives for vulnerable populations.

ClimateCrop, founded in 2021 and based in Ness Ziona, specializes in agricultural technologies that enhance the ability of plants to store carbon and energy. The company employs gene editing techniques to optimize the performance of crops, enabling them to harness greater energy and improve resilience against extreme weather conditions. This innovative approach not only facilitates better adaptation to current and future climate challenges but also supports agricultural companies in achieving higher yields, whether in biomass or fruit production.

Finless Foods Inc. is a biotechnology company based in Emeryville, California, that specializes in producing seafood products for human consumption using cellular-agriculture technologies. Founded in 2017, the company focuses on cultivating marine-animal cells to create sustainable fish and seafood alternatives, including bluefin tuna. Finless Foods aims to provide a variety of food options that cater to diverse tastes and dietary preferences while promoting responsible production practices. By offering accessible plant-based and cell-cultured seafood alternatives, the company seeks to contribute to better ocean health and foster a more sustainable future for food consumption.

Bloomlabs provides a method to catalyze waste value by regenerating it as adaptable and appealing bio-plastics and textile fibers. It envisions a future in which outmoded, resource-intensive processes are phased out in favor of cutting-edge, sustainable, and scalable alternatives.

Cayuga Biotech is a startup focused on the development of innovative hemostatic drugs and devices aimed at reducing uncontrollable bleeding, a major cause of death from traumatic injuries. The company utilizes a polyphosphate-based drug that enhances the body's natural clotting process at the injury site, thereby minimizing the risk of side effects associated with bleeding. Cayuga's pipeline includes a clinic-ready drug designed for life-threatening hemorrhage and additional therapeutics in the discovery stage targeting rare inherited bleeding disorders, central nervous system bleeding, severe burns, and non-healing wounds. Through its biomimetic therapeutics technology, Cayuga Biotech seeks to harness the body's innate ability to promote healing and improve survival rates, while also reducing disability resulting from trauma.

California Cultured is a food company based in Davis, California, that specializes in creating sustainable, lab-grown cocoa and coffee through advanced cellular agriculture techniques. Founded in 2020, the company focuses on producing cocoa that is less bitter and requires less sugar, while also ensuring its products are healthier for consumers. By stimulating cocoa cell growth using common food ingredients, California Cultured aims to provide high-quality cocoa products that are free from the ethical issues traditionally associated with cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious and sustainable cocoa without the environmental and social drawbacks of conventional methods.

Avisa Myko Inc. is a biotechnology company based in San Francisco, California, specializing in the production of natural, water-soluble melanin through precision fermentation technology. This innovative approach allows the company to manufacture melanin at scale and at an affordable cost, making it suitable for diverse applications across various industries. Avisa Myko's melanin serves multiple purposes, including protection against ionizing radiation and use in electricity generation. Its high-purity melanin is easily redissolved, facilitating incorporation into products such as cosmetics, biomedicine, organic semiconductors, biosensors, latex products, and fabrics. The company is also developing a prototype sunscreen that utilizes melanin as an ultraviolet blocker, distinguishing itself by avoiding traditional chemical or mineral UV blockers. Through its patented technology, Avisa Myko aims to contribute to better health and environmental sustainability.

Reactosome is a biotechnology company that develops synthetic nuclei for gene therapy. Its core product, a synthetic nucleus, operates continuously within cells, mimicking the natural nucleus to affect multiple genes simultaneously. This approach aims to enhance the safety and longevity of gene expression, thereby enabling the development of treatments for complex diseases such as cancer and age-related disorders.

Bioeutectics is a company focused on enhancing the sustainability of industrial processes by providing high-performance, natural solvents. Utilizing proprietary eutectic technology, Bioeutectics mimics the natural solvent production methods of plants and relies on 100% renewable resources. This innovative approach enables the company to replace traditional petrochemical solvents with eco-friendly alternatives in various industries, including food, pharmaceuticals, and personal care. The solvents produced are non-toxic, biodegradable, and customizable, allowing for tailored solutions that meet specific industry needs while promoting environmental responsibility. Through its commitment to sustainable practices, Bioeutectics positions itself as a leader in the production of green solvents, contributing to a more sustainable future.

ZymoChem, Inc. is a biotechnology company based in Emeryville, California, founded in 2013. The company specializes in developing microbes and bioprocesses that convert renewable feedstocks, such as sugars, into bio-based chemicals. ZymoChem's innovative platform focuses on creating eco-friendly chemical solutions while minimizing carbon dioxide emissions during production. By engineering novel microbes and establishing cost-effective bioprocesses, the company enhances the biological conversion of renewable materials into various industrial chemicals. This approach not only lowers production costs for clients but also contributes to sustainability by promoting a carbon-efficient manufacturing process. ZymoChem aims to support the transition to a real-zero economy by providing alternatives that reduce carbon emissions across product development, usage, and disposal.

Chronus Health, Inc. is a medical technology company that specializes in developing a portable diagnostic device capable of delivering rapid point-of-care lab results, specifically for complete blood count and comprehensive metabolic panel tests. Founded in 2017 and headquartered in Mountain View, California, the company utilizes advanced microfluidics and semiconductor technology, combined with data analytics, to provide healthcare providers with real-time diagnostic capabilities. This innovative system allows for the delivery of lab results within minutes, significantly enhancing the speed of diagnosis and improving patient outcomes by enabling timely and informed treatment decisions.

Sun Genomics, Inc. is a microbiome health company based in San Diego, California, specializing in customized probiotics aimed at addressing dysbiosis. Founded in 2014, the company’s flagship product, Floré, combines a gut microbiome test with personalized probiotic formulations tailored to individual gut profiles, assessed through whole-genome sequencing. The Floré Gut Test includes a microflora collection kit, a comprehensive microflora profile analysis, and wellness consultations. Additionally, Sun Genomics offers Floré Tots, a probiotic solution designed for children up to age 12, which comes in a convenient powder form that can be easily mixed with beverages. The company sells its products online, providing an automatic renewal service to enhance customer convenience.

Unlocked Labs specializes in the development of genetically optimized probiotics aimed at addressing chronic health conditions. The company focuses on activating dormant microbial abilities within a safe and established framework. Its rigorously tested probiotic strains are specifically designed to target and eliminate harmful compounds in the gastrointestinal tract. Unlocked Labs' inaugural product is formulated to reduce the risk of kidney stones by digesting stone-forming compounds that may be ingested from healthy foods, such as leafy vegetables. By utilizing alternative regulatory pathways, the company seeks to expedite the availability of safe and effective probiotic solutions for consumers, enabling them to detoxify their bodies and manage acid levels affordably and effectively.

RyboDyn is a biotechnology research company focused on developing innovative therapeutics aimed at training the immune system to identify and eliminate cancer from within the body. By leveraging cutting-edge scientific breakthroughs, RyboDyn creates advanced treatments that promise significant improvements in the management of terminal diseases and various ailments. The company's commitment to enhancing medicine through its research positions it at the forefront of the fight against cancer, with the potential to transform patient care and outcomes.

Prellis Biologics, Inc. is a biotechnology company based in San Francisco, California, that specializes in bioprinting human tissues for drug development and organ transplantation. Founded in 2016, the company focuses on overcoming the challenges of creating vascularized human tissues and organs, aiming to revolutionize healthcare. Its innovative technology allows for the precise engineering of human tissues, including lymph node organoids, which can replicate human immune responses for various applications such as antibody discovery and tumor-immune modeling. Prellis Biologics offers a range of products, including TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X, which collectively enhance early-stage drug discovery and translational pharmacology.

Hypercell Technologies specializes in developing innovative tools for controlling infectious diseases in animals. The company's core focus is on creating rapid, accurate diagnostic tools using molecular biology techniques, which enable veterinarians to detect and manage infections swiftly. Additionally, Hypercell develops monoclonal antibodies designed to proactively control viruses in production animal reservoirs, aiming to prevent potential zoonotic disease outbreaks in humans by addressing the source in animals.

Lillianah Technologies is a company dedicated to developing innovative carbon capture technology aimed at restoring marine ecosystems affected by pollution and other environmental challenges. Comprising a team of scientists, Lillianah focuses on optimizing the biological pump in oceans, which is crucial for maintaining ecological balance. By harnessing the ocean's potential, the company seeks to address the detrimental impacts of human activity, such as fertilizer runoff, and contribute to reversing environmental degradation. Through its efforts, Lillianah Technologies aspires to create sustainable solutions that benefit both the oceans and the broader environment.

BioFluff is a manufacturer specializing in plant-based fur designed to serve the fashion industry by providing a sustainable alternative to animal and plastic fur. The company utilizes a patented process along with retrofitted equipment to ensure a scalable production of its eco-friendly materials. Sourced from organic renewable fiber plants, BioFluff’s products are developed without gene splicing, gene editing, or the use of petrochemicals and unsustainable raw-oil derivatives. This commitment to sustainability extends to its customization services, allowing clients to personalize their materials according to specific features such as fur length, fiber density, color, top fur strength, bottom fur insulation properties, and suppleness. By combining innovation with customization options, BioFluff aims to meet the growing demand for luxury, sustainable textiles within the fashion industry.

Pyrone Systems, established in 2021, specializes in the development of biopesticides that integrate biology with chemistry. The company focuses on creating safe, effective, and sustainable products through innovative, biology-based methodologies. Pyrone Systems aims to produce bio-based chemicals that can replace harmful petrochemicals, contributing to environmental sustainability and promoting safer agricultural practices. By prioritizing a biology-driven approach, the company seeks to provide efficient alternatives that minimize the ecological impact of traditional chemical products.

BioAesthetics LLC, founded in 2015 as a spin-out from Tulane University, is dedicated to improving reconstruction options for breast cancer patients post-mastectomy. The company specializes in developing tissue-engineered nipple-areolar complex (NAC) grafts, which are designed to be used during the breast reconstruction phase. These off-the-shelf, acellular NAC grafts serve as a framework for the patient's own cells to regenerate their nipple and areola, providing a more natural outcome. The company is based in New Orleans, Louisiana.

FREZENT is a biotechnology company focused on developing innovative therapeutics for advanced-stage cancer patients. It specializes in creating biological inhibitors that target cancer-specific lipid metabolism, aiming to prevent the reactivation of dormant cancer cells.

Gatehouse Bio is a biotech company based in Waltham, Massachusetts, founded in 2016. The company specializes in the development of therapies utilizing a novel bioinformatics platform that focuses on small ribonucleic acid (RNA) biomarkers. This platform is designed to classify patient samples with binary accuracy and identifies disease-associated mutations, enabling the creation of targeted therapeutics. By employing artificial intelligence, Gatehouse Bio aims to analyze small RNA genes and design oligonucleotides that can effectively counteract the effects of these mutations. Their research and development efforts target therapeutic areas with known heterogeneity, such as fibrosis, inflammation, and neurodegeneration, with the goal of unlocking the potential for improved patient outcomes through personalized medicine.

Diptera.ai is a Jerusalem-based company specializing in innovative mosquito control solutions. The firm has developed a technology that employs the sterile insect technique, utilizing advanced optics, computer vision, and artificial intelligence. Its ready-to-use module is designed to release sterile male mosquitoes over several weeks, allowing municipal corporations to implement large-scale mosquito control initiatives effectively. This approach eliminates the need for traditional mosquito rearing and sorting facilities, making the technology more affordable and accessible for municipalities. By focusing on biological solutions, Diptera.ai aims to address the challenges posed by mosquito-borne diseases and improve public health outcomes.

Calder Biosciences is a biotechnology company focused on developing advanced vaccines to combat life-threatening viruses. Recognizing that traditional vaccines often fail to provide adequate protection against evolving viral threats, Calder employs its proprietary 3D-Vaxlock technology, which utilizes structure-based design to enhance the stability and efficacy of vaccine candidates. This innovative platform creates molecular staples that maintain vaccines in their most effective configurations, addressing the common shortcomings of subunit vaccines, such as limited potency and shelf-life. Calder's current projects include a universal flu vaccine aimed at covering all seasonal strains and a respiratory syncytial virus (RSV) vaccine tailored for the elderly. By prioritizing the development of vaccines with exceptional safety, efficacy, and durability, Calder aims to reduce severe disease and mortality rates while alleviating the burden on healthcare systems, ultimately contributing to healthier lives for vulnerable populations.

BryoSphere is a company specializing in the manufacturing of specialty chemicals, employing moss plants and biotechnology methods in the production of their goods. The company is currently focused on the development of two key products: one for addressing skin hyperpigmentation in topical treatments, and another as an anti-cancer drug.

Xias Bio is a biotechnology startup focused on the development and production of recombinant proteins. The company specializes in creating non-immunogenic natural motifs that enhance the delivery of functionalities for various applications in research, beauty, and healthcare. Xias Bio's innovative platform provides a versatile, animal product-free biomaterial that offers tailored biological functionality. This approach enables pharmaceutical and cosmetic companies to access designer proteins that serve as non-immunogenic, non-toxic alternatives to traditional synthetic and animal-derived materials. By improving attributes such as gel and film formation, as well as antioxidant properties, Xias Bio addresses the limitations of conventional solutions, positioning itself as a valuable partner in the biotechnology sector.

Veloz Bio is a biotechnology company founded in 2021 and based in Monterrey, Nuevo León. The company specializes in molecular farming to develop and manufacture animal-free and alternative proteins. Utilizing a rapid protein production system, Veloz Bio leverages efficient plant metabolism to create sustainable and affordable protein solutions. This innovative approach enables the company to support biotechnology firms by providing expertise in key areas such as protein production, supercritical fluid extraction, and membrane purification. Through its focus on scalable protein development, Veloz Bio aims to contribute to the advancement of alternative protein sources in the food industry.

QuantumCyte, Inc. is a technology platform company focused on advancing cancer treatment and drug efficacy prediction through innovative cell analysis systems. Established in 2014 and headquartered in Sunnyvale, California, QuantumCyte develops automated microdissection solutions that utilize digital tissue maps to pinpoint regions of interest containing critical biomarkers for treatment decisions. By leveraging artificial intelligence in its digital pathology and molecular analysis technologies, the company provides healthcare providers with precise cellular data, enabling in-depth single-cell analysis that enhances understanding of immune system and cancer biology. Through its efforts, QuantumCyte aims to improve cancer outcomes and contribute to more effective therapeutic interventions.

CroBio Ltd is an agricultural biotechnology company that focuses on developing innovative solutions to enhance water retention in soil, particularly in the face of global agricultural drought. Founded in 2019 and based in Macclesfield, United Kingdom, the company specializes in genetically engineered root-associated bacteria that create a self-sustaining, biologically active material capable of improving soil health. By harnessing expertise in microbiology and engineering, CroBio aims to provide environmentally sustainable solutions that address the challenges of water scarcity in agriculture.

Cell BioEngines, Inc. is a clinical-stage biotechnology company dedicated to the development of allogeneic "off-the-shelf" stem cell therapies aimed at treating various human diseases. The company employs a unique blood stem cell-derived epigenetic platform designed to enhance donor source availability, improve cellular potency, and simplify the manufacturing processes of clinical-grade cell products. In addition, Cell BioEngines is advancing a pre-clinical stage immunotherapy platform focused on making all cancers treatable, thereby offering the potential for long-lasting benefits in oncology. Through its innovative approach, Cell BioEngines seeks to address significant challenges in the field of cell-based therapies and improve patient outcomes.

Avisa Myko Inc. is a biotechnology company based in San Francisco, California, specializing in the production of natural, water-soluble melanin through precision fermentation technology. This innovative approach allows the company to manufacture melanin at scale and at an affordable cost, making it suitable for diverse applications across various industries. Avisa Myko's melanin serves multiple purposes, including protection against ionizing radiation and use in electricity generation. Its high-purity melanin is easily redissolved, facilitating incorporation into products such as cosmetics, biomedicine, organic semiconductors, biosensors, latex products, and fabrics. The company is also developing a prototype sunscreen that utilizes melanin as an ultraviolet blocker, distinguishing itself by avoiding traditional chemical or mineral UV blockers. Through its patented technology, Avisa Myko aims to contribute to better health and environmental sustainability.

Transition Biomining is a technology-focused company specializing in copper ore mining. It employs data-driven methods to enhance copper extraction and mining efficiency. The company's core innovation lies in optimizing microbial communities for heap-leaching operations, aiming to boost metal recovery rates, expedite extraction, and minimize environmental impact. By harnessing the power of microbiomes, Transition Biomining provides sustainable and data-driven solutions to improve clients' extraction processes in both new and existing heap-leaching operations.

Bloomlabs provides a method to catalyze waste value by regenerating it as adaptable and appealing bio-plastics and textile fibers. It envisions a future in which outmoded, resource-intensive processes are phased out in favor of cutting-edge, sustainable, and scalable alternatives.

TippingPoint Biosciences is focused on developing innovative therapeutics that address diseases caused by defects in DNA packaging, with an emphasis on conditions such as cancer and neurodegenerative disorders. Utilizing a specialized drug discovery platform, the company aims to identify new treatment options that specifically target unique genome packaging states associated with various diseases. This approach not only facilitates the treatment of cancer but also holds potential for advancing stem cell therapies by correcting dysfunctional genome packaging. Through its research and development efforts, TippingPoint Biosciences seeks to provide effective solutions for complex medical challenges.

California Cultured is a food company based in Davis, California, that specializes in creating sustainable, lab-grown cocoa and coffee through advanced cellular agriculture techniques. Founded in 2020, the company focuses on producing cocoa that is less bitter and requires less sugar, while also ensuring its products are healthier for consumers. By stimulating cocoa cell growth using common food ingredients, California Cultured aims to provide high-quality cocoa products that are free from the ethical issues traditionally associated with cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious and sustainable cocoa without the environmental and social drawbacks of conventional methods.

Pannex Therapeutics is a New York-based biopharmaceutical startup focused on developing innovative therapies for cancer treatment. The company specializes in creating Pannexin 1 channel (Panx1) blockers, which represent a novel class of drugs aimed at inhibiting multiple pathways that contribute to the growth, spread, and survival of cancer cells. Pannex Therapeutics' therapies are designed to provide high specificity for cancer cells, ensuring effective treatment while minimizing side effects and the risk of addiction. By advancing these promising treatments, the company seeks to transform cancer therapy and improve patient outcomes.

VIA BioFuels is a biotechnology research company based in Houston, Texas, founded in 2023. The company specializes in the development of proprietary engineered yeast strains, specifically S. cerevisiae, which produce aromatic 3-methyl anisole (3-MA) from conventional ethanol feedstocks. VIA BioFuels’ technology is designed to be scalable, utilizing existing ethanol production methods and infrastructure. The high-purity 3-MA produced can be transformed into various valuable compounds, enhancing the market potential of the output and allowing consumers to substitute traditional fuels without blending restrictions.

Diadem Biotherapeutics is a biotechnology company dedicated to developing bio-therapeutical materials through organic methods. The company specializes in the creation of exosomes, which are cell-free vesicles engineered to signal through validated targets. Diadem's therapeutic platform aims to treat a variety of chronic inflammatory conditions, autoimmune diseases, and cancers. By focusing on the genetic engineering, manufacturing, and purification of these exosomes, Diadem provides innovative solutions for clinicians to effectively address immunopathologies and improve patient outcomes.

AlkaLi Labs is a biotechnology research company founded in 2023 and based in San Francisco, California. The company focuses on developing biological solutions to unlock domestic mineral resources. Currently operating in stealth mode, AlkaLi Labs aims to innovate in the field of biotechnology by leveraging natural processes to enhance resource extraction and sustainability.

Kresko RNAtech is a biotechnology company focused on the development and production of nutraceuticals. It specializes in identifying bioactive ribonucleic acids (RNAs) from natural sources, utilizing advanced techniques such as machine learning and bioinformatics. By discovering RNAs that may offer health benefits, Kresko RNAtech aims to assist researchers in enhancing human well-being and addressing the challenges posed by stressful and changing environments through innovative RNA technologies.

Gozen Bioworks offers solutions and biomaterials developed with a biomimicry approach by combining science, art, philosophy, and design to raise awareness and provide help to the planet, living creatures, and humanity. They develop and invent high-performance microbe-derived materials from natural inputs, such as next-generation leather, biotextiles, bioplastics, packaging, and interior materials.

Forte Protein is a company founded in 2021 and based in Trumansburg, New York, that focuses on developing an innovative expression system for the production of bio-identical animal proteins. The company aims to provide a sustainable alternative to traditional animal agriculture by offering a complete range of plant-based proteins that mimic the nutritional profiles and functional characteristics of animal proteins. By doing so, Forte Protein seeks to eliminate the carbon footprint associated with conventional animal farming, catering to the growing demand for environmentally friendly protein sources among consumers.

Geltor, Inc. is a biodesign company focused on producing bioactive, animal-free collagens and proteins for a range of applications including beauty and nutrition. The company offers innovative products such as Collume, a bio-designed collagen technology that supports skincare cellular regeneration, and HumaColl21, which enhances the skin's appearance by boosting collagen, elastin, laminin, and fibronectin levels. Geltor also provides vegan collagen peptides and other novel proteins for use in functional foods and nutraceuticals. Established in 2015 and based in San Leandro, California, Geltor is committed to sustainable practices and aims to support a plant-based future through its clinically validated, biocompatible materials.

Unibaio specializes in biodegradable nano-encapsulation technology designed to optimize the delivery of agrochemicals, thereby reducing the need for harmful chemicals in pesticide formulations. The company's innovative particles enable pesticide manufacturers to comply with stringent environmental regulations while maintaining effective chemical use. Unibaio's technology enhances the uptake of fertilizers and pesticides, minimizing runoff and lowering application doses, which ultimately decreases costs for farmers. By utilizing natural compounds such as shrimp waste and clay, Unibaio adheres to a circular model in producing its micro-nanocapsules. This approach supports the development of both traditional and organic agricultural products, improving yield and competitiveness in the sector while promoting the health and well-being of crops.

Stämm Biotech is a San Francisco-based company specializing in advanced bioproduction systems designed to address the scaling challenges in the biotech industry. Founded in 2014, Stämm has developed an innovative biomanufacturing solution that integrates microfluidics, electroporation, and robotics, resulting in a compact, all-in-one Bioprocessor. This system has demonstrated productivity levels at least 70 times greater than traditional bioreactors, enabling clients to miniaturize bioreactors and optimize conditions more efficiently. Stämm's technology incorporates various sensors to monitor biological, physical, and chemical variations throughout the bioprocess, facilitating a streamlined approach to microbial growth and monoclonal cell line development. By transforming large-scale biotech operations into a more manageable micro-factory network, Stämm aims to unlock significant market potential in the coming years.

Vitarka Therapeutics is a London-based company that specializes in developing medical technologies and solutions aimed at treating various types of cancer. The company has created a targeted non-viral delivery platform designed for intracellular targets, particularly in oncology, neuroscience, and neurodegeneration. This innovative platform works by activating the immune system and normalizing tumor vasculature, significantly improving outcomes for late-stage cancer patients, including those with lung, colon, and breast cancers. By utilizing re-engineered pore-forming proteins, Vitarka Therapeutics enables cell-specific targeting and endosomal release of therapeutic cargo, providing cancer patients with improved prospects for leading normal lives and maintaining hope for the future.

Beeflow S.A., founded in 2016 and based in Buenos Aires, Argentina, specializes in professional pollination services that leverage scientific knowledge and technology to enhance bee health and efficiency. The company develops organic compounds that improve the immune systems of bees and train them to pollinate specific crops, such as blueberries, almonds, raspberries, and kiwifruit. By providing these specialized pollination services, Beeflow enables farmers to significantly increase crop yields, with reported improvements ranging from 20% to 90%, while simultaneously addressing the decline in bee populations. Through its innovative approach, Beeflow aims to support agricultural productivity and ecosystem sustainability.

Cayuga Biotech is a startup focused on the development of innovative hemostatic drugs and devices aimed at reducing uncontrollable bleeding, a major cause of death from traumatic injuries. The company utilizes a polyphosphate-based drug that enhances the body's natural clotting process at the injury site, thereby minimizing the risk of side effects associated with bleeding. Cayuga's pipeline includes a clinic-ready drug designed for life-threatening hemorrhage and additional therapeutics in the discovery stage targeting rare inherited bleeding disorders, central nervous system bleeding, severe burns, and non-healing wounds. Through its biomimetic therapeutics technology, Cayuga Biotech seeks to harness the body's innate ability to promote healing and improve survival rates, while also reducing disability resulting from trauma.

Particella is a biotechnology company that specializes in developing a proprietary oral lipid nanoparticle technology designed to deliver mRNA and other nucleic acids. This innovative approach aims to transform the administration of biological medicines by utilizing the intestinal tract to facilitate the secretion of proteins into the bloodstream. By enabling the oral delivery of protein biologics, Particella's technology seeks to address the limitations of current methods, ultimately allowing healthcare providers to prevent gastrointestinal diseases in patients more effectively. The company's advancements hold the potential to create a new category of medicines, enhancing the accessibility and efficacy of treatments.

DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing innovative gene therapy treatments for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes advanced oral lipid nanoparticle technology to deliver mRNA and plasmid DNA directly to intestinal stem cells. This approach aims to address the root causes of gastrointestinal diseases, including Familial Adenomatous Polyposis (FAP), a hereditary condition that can lead to colorectal cancer and often necessitates invasive surgical interventions. DNALite's therapies seek to transform protein biologics into oral drugs, allowing for more effective and less invasive treatment options.

Mimio Health is a nutraceutical company dedicated to the research and development of fasting mimetic supplements. The company has created a patent-pending formulation that utilizes a carefully chosen blend of bioactive human metabolites designed to mimic the body's natural response to fasting. This innovative approach aims to replicate the cellular health benefits associated with fasting, enabling users to experience anti-inflammatory and antioxidant effects that may help combat age-related chronic inflammation and cellular damage, without the need for actual fasting. Through its scientific research, Mimio Health seeks to enhance overall wellness and longevity.

FluoSphera is a biotechnology company focused on developing safer and more effective drugs. It aims to minimize adverse side effects and reduce reliance on animal testing by leveraging innovative drug discovery technologies. This enables FluoSphera's partners to better understand human physiological responses and safeguard populations from harmful chemicals more efficiently.

CroBio Ltd is an agricultural biotechnology company that focuses on developing innovative solutions to enhance water retention in soil, particularly in the face of global agricultural drought. Founded in 2019 and based in Macclesfield, United Kingdom, the company specializes in genetically engineered root-associated bacteria that create a self-sustaining, biologically active material capable of improving soil health. By harnessing expertise in microbiology and engineering, CroBio aims to provide environmentally sustainable solutions that address the challenges of water scarcity in agriculture.

Bioeutectics is a company focused on enhancing the sustainability of industrial processes by providing high-performance, natural solvents. Utilizing proprietary eutectic technology, Bioeutectics mimics the natural solvent production methods of plants and relies on 100% renewable resources. This innovative approach enables the company to replace traditional petrochemical solvents with eco-friendly alternatives in various industries, including food, pharmaceuticals, and personal care. The solvents produced are non-toxic, biodegradable, and customizable, allowing for tailored solutions that meet specific industry needs while promoting environmental responsibility. Through its commitment to sustainable practices, Bioeutectics positions itself as a leader in the production of green solvents, contributing to a more sustainable future.

BiomeSense, Inc. is a Chicago-based company founded in 2018 that focuses on developing a comprehensive platform for microbiome data collection and analysis. Its primary innovation is the GutLab, a "smart bathroom" system designed for continuous, at-home monitoring of the human gut microbiome. This technology is integrated with the MetaBiome time-series analytics platform, offering a seamless end-to-end solution that enables real-time tracking of microbiome changes and their correlation with clinical outcomes. By generating and analyzing extensive longitudinal microbiome datasets, BiomeSense aims to discover and commercialize novel microbiome biomarkers, providing healthcare professionals with a high-resolution microbiome database. This resource supports the development of advanced microbiome-based therapeutics and consumer products, ultimately enhancing precision medicine and improving health outcomes.

Lillianah Technologies is a company dedicated to developing innovative carbon capture technology aimed at restoring marine ecosystems affected by pollution and other environmental challenges. Comprising a team of scientists, Lillianah focuses on optimizing the biological pump in oceans, which is crucial for maintaining ecological balance. By harnessing the ocean's potential, the company seeks to address the detrimental impacts of human activity, such as fertilizer runoff, and contribute to reversing environmental degradation. Through its efforts, Lillianah Technologies aspires to create sustainable solutions that benefit both the oceans and the broader environment.

Veloz Bio is a biotechnology company founded in 2021 and based in Monterrey, Nuevo León. The company specializes in molecular farming to develop and manufacture animal-free and alternative proteins. Utilizing a rapid protein production system, Veloz Bio leverages efficient plant metabolism to create sustainable and affordable protein solutions. This innovative approach enables the company to support biotechnology firms by providing expertise in key areas such as protein production, supercritical fluid extraction, and membrane purification. Through its focus on scalable protein development, Veloz Bio aims to contribute to the advancement of alternative protein sources in the food industry.

Multus is a London-based company established in 2019 that specializes in providing tailored growth media solutions for the cultivated meat industry. By utilizing a machine learning-based approach, Multus develops completely animal-free growth media designed specifically for the efficient growth of animal cells. This innovative technology enables cultivated meat companies to scale their production affordably and sustainably, allowing them to focus on creating delicious and environmentally friendly meat alternatives. Additionally, Multus optimizes a variety of growth factor proteins produced by genetically engineered microorganisms, thereby eliminating the reliance on traditional animal serum-based media. Through its efforts, Multus aims to address the diverse needs of various animal cell types and tissues, facilitating the growth of the cultivated meat sector while significantly reducing the environmental and economic impacts associated with conventional meat production.

Michroma Corporation is a biotechnology company that specializes in producing natural thermostable colorants derived from filamentous fungi for the food and cosmetics industries. Founded in 2019, the company operates from locations in San Francisco, California, and Rosario, Argentina. By leveraging synthetic biology, Michroma develops proprietary fungal strains that can be cultivated in bioreactors, allowing for the sustainable and cost-effective production of high-performance ingredients. Its initial offerings focus on pH-stable and heat-stable colorants, which are designed to replace synthetic pigments and those sourced from animals and plants. In addition to colorants, Michroma is also engaged in the production of mycoprotein and other innovative ingredients, collaborating with leading companies in the food and beverage and cosmetic sectors.

Atlantic Fish Company is focused on producing cultivated seafood through cellular agriculture, operating from its headquarters in Raleigh-Durham, North Carolina. The company aims to provide sustainable seafood options by cultivating fish in a controlled environment. This innovative approach allows Atlantic Fish Company to offer fresh fish meat that maintains the natural taste while minimizing the environmental impact associated with traditional fishing practices. By leveraging cellular agriculture, the company seeks to meet the growing demand for sustainable protein sources.