IndieBio

IndieBio is an accelerator that supports startups using biology to solve major problems, delivering four-month programs for companies and teams with ideas. Based in San Francisco with an office in New York, it focuses on life sciences, biotechnology and synthetic biology, investing in seed and early-stage ventures that place biology at the core of their technology across products, processes and software. The program favors teams with two or more co-founders and generally provides equity-based funding in the early stages, often combining direct investments with additional financing options. Founded in 2014, IndieBio operates within the SOSV accelerator network, a global platform that supports portfolio companies through mentorship, resources and cross-border programs.

Arvind Gupta

Founder

Alexander Hall-Daniels

Associate

Past deals in AgTech

Capro-X

Seed Round in 2025
Capro-X is an ag-tech company focused on sustainability in the dairy industry. It develops fermentation bioprocess technology to convert acid whey, a dairy waste stream, into valuable products such as bio-oils, biofuels, and bioplastics, while producing clean water. The WheyAway treatment uses naturally occurring, non-GMO microbes to upgrade dairy waste on site at the point of generation. By upcycling acid from dairy waste, Capro-X helps dairy producers reduce waste and improve sustainability and yield over time. Founded in 2017 and based in Ithaca, New York, Capro-X serves dairy processors seeking to turn waste streams into value.

Puna Bio

Series A in 2025
Puna Bio specializes in developing biological products for the agricultural sector. Based in Buenos Aires, Argentina, the company focuses on enhancing crop nutrition using extremophile microorganisms, aiming to improve yields and soil quality sustainably.

Farm Minerals

Seed Round in 2024
Farm Minerals is a pioneering agricultural company that produces innovative, emissions-free NPK fertilizers at market prices, without compromising on quality or cost. Utilizing proprietary carbon capsule technology, the company enhances nutrient bioavailability, boosting efficiency up to 100 times compared to traditional inputs. By avoiding the Haber-Bosch process, Farm Minerals eliminates CO₂ emissions, reduces nutrient runoff, and minimizes waste. Its product line combines essential macro and microelements, promoting crop performance and animal health, and contributing to sustainable, high-yield agriculture.

Asterix Foods

Convertible Note in 2024
Asterix Foods is a biotechnology company based in Tel Aviv, Israel, founded in 2022. The company specializes in developing protein production through plant-cell culture techniques, focusing on the creation of bioactive proteins for food applications. Asterix Foods aims to provide scalable, functional, and complex proteins that are derived from plant cell cultures, offering an animal-free alternative for consumers.

Quorum Earth

Seed Round in 2024
Quorum Earth, based in Brooklyn, New York, is a pioneering agricultural technology company. It specializes in the development of innovative, eco-friendly pesticides, harnessing the power of the fungal kingdom to create products that are safe for the planet and effective in controlling pests. Currently, the company operates in stealth mode.

Mothership Materials

Seed Round in 2024
Mothership Materials specializes in converting agricultural waste into valuable biomolecules using its proprietary Targeted Molecular Recovery (TMR) technology. The company's process efficiently extracts proteins, lipids, antioxidants, sugars, and cellulose from waste streams, enabling agricultural producers and waste managers to create a circular economy and maximize waste value.

Calyx

Funding Round in 2024
Calyx develops advanced sensor platforms that monitor various parameters in poultry farming with exceptional specificity and sensitivity. The company combines AI computer vision technology, bio-engineered sensors, and data science to address complex challenges in the poultry industry.

PhytoGenesis

Seed Round in 2024
PhytoGenesis is a company that specializes in developing sustainable plant protection products. It focuses on creating safe and non-toxic alternatives to traditional fungicides and pesticides, using plant-based compounds. The company's technology ensures effectiveness across a broad spectrum of crops, including grains, feed, fiber, oil, vegetables, and fruits. PhytoGenesis aims to minimize environmental impact while maintaining crop health and productivity, contributing to global food security.

Capro-X

Seed Round in 2024
Capro-X is an ag-tech company focused on sustainability in the dairy industry. It develops fermentation bioprocess technology to convert acid whey, a dairy waste stream, into valuable products such as bio-oils, biofuels, and bioplastics, while producing clean water. The WheyAway treatment uses naturally occurring, non-GMO microbes to upgrade dairy waste on site at the point of generation. By upcycling acid from dairy waste, Capro-X helps dairy producers reduce waste and improve sustainability and yield over time. Founded in 2017 and based in Ithaca, New York, Capro-X serves dairy processors seeking to turn waste streams into value.

Farm Minerals

Seed Round in 2024
Farm Minerals is a pioneering agricultural company that produces innovative, emissions-free NPK fertilizers at market prices, without compromising on quality or cost. Utilizing proprietary carbon capsule technology, the company enhances nutrient bioavailability, boosting efficiency up to 100 times compared to traditional inputs. By avoiding the Haber-Bosch process, Farm Minerals eliminates CO₂ emissions, reduces nutrient runoff, and minimizes waste. Its product line combines essential macro and microelements, promoting crop performance and animal health, and contributing to sustainable, high-yield agriculture.

ClimateCrop

Seed Round in 2024
ClimateCrop develops gene editing and related plant technologies to enable crops to store more carbon and energy, with the goal of increasing yields in biomass and fruit. The approach also enhances crop resilience to extreme weather, supporting climate adaptation and more reliable production for agricultural companies. Founded in 2021 and based in Ness Ziona, the company focuses on leveraging plant energy capture to boost productivity.

California Cultured

Series A in 2024
California Cultured is a food company that uses cellular agriculture to produce cocoa and coffee, with the aim of delivering sustainable, lab-grown ingredients. Its cocoa is described as less bitter and requiring less sugar to achieve flavor, enabling premium quality products with a smaller environmental footprint. The company seeks to address social and environmental concerns linked to traditional cocoa production by avoiding practices such as slavery, deforestation, and child labor. California Cultured was founded in 2020 and is based in Davis, California.

Hypercell Technologies

Seed Round in 2023
Hypercell Technologies develops tools to control infectious diseases in animals, including diagnostics and monoclonal antibodies designed to curb viruses in production animal reservoirs. The company employs molecular biology to create rapid, on-farm diagnostics that enable veterinarians to detect infections quickly and implement preventive measures. By focusing on proactive control of viruses in animal populations, Hypercell aims to reduce the emergence of diseases that could threaten human health and improve animal health management across production settings.

Cereswaves

Seed Round in 2023
Cereswaves is a specialized machinery manufacturer focused on mining, agriculture, and construction processes.

California Cultured

Convertible Note in 2023
California Cultured is a food company that uses cellular agriculture to produce cocoa and coffee, with the aim of delivering sustainable, lab-grown ingredients. Its cocoa is described as less bitter and requiring less sugar to achieve flavor, enabling premium quality products with a smaller environmental footprint. The company seeks to address social and environmental concerns linked to traditional cocoa production by avoiding practices such as slavery, deforestation, and child labor. California Cultured was founded in 2020 and is based in Davis, California.

Protogenix

Convertible Note in 2023
Protogenix develops a platform technology to replace the mammalian cell system for manufacturing complex proteins. The decentralized plug-and-play platform enables high-yield production at greater speed and lower cost, helping food and pharmaceutical producers access sustainably produced, safe protein ingredients while aiming to reduce the carbon footprint of animal agriculture.

Unibaio

Pre Seed Round in 2023
Unibaio develops biodegradable nano-encapsulation technology that optimizes agrochemical delivery. Its particles enable pesticide companies to modify formulations, meeting stringent environmental regulations without replacing chemicals used by farmers. This reduces application doses and toxicity levels, lowering farmer costs and improving yields.

Atlantic Fish Company

Pre Seed Round in 2023
Atlantic Fish Company is focused on producing cultivated seafood through cellular agriculture, operating from its headquarters in Raleigh-Durham, North Carolina. The company aims to provide sustainable seafood options by cultivating fish in a controlled environment. This innovative approach allows Atlantic Fish Company to offer fresh fish meat that maintains the natural taste while minimizing the environmental impact associated with traditional fishing practices. By leveraging cellular agriculture, the company seeks to meet the growing demand for sustainable protein sources.

Atlantic Fish Company

Seed Round in 2022
Atlantic Fish Company is focused on producing cultivated seafood through cellular agriculture, operating from its headquarters in Raleigh-Durham, North Carolina. The company aims to provide sustainable seafood options by cultivating fish in a controlled environment. This innovative approach allows Atlantic Fish Company to offer fresh fish meat that maintains the natural taste while minimizing the environmental impact associated with traditional fishing practices. By leveraging cellular agriculture, the company seeks to meet the growing demand for sustainable protein sources.

Protogenix

Seed Round in 2022
Protogenix develops a platform technology to replace the mammalian cell system for manufacturing complex proteins. The decentralized plug-and-play platform enables high-yield production at greater speed and lower cost, helping food and pharmaceutical producers access sustainably produced, safe protein ingredients while aiming to reduce the carbon footprint of animal agriculture.

Puna Bio

Seed Round in 2022
Puna Bio specializes in developing biological products for the agricultural sector. Based in Buenos Aires, Argentina, the company focuses on enhancing crop nutrition using extremophile microorganisms, aiming to improve yields and soil quality sustainably.

ClimateCrop

Seed Round in 2022
ClimateCrop develops gene editing and related plant technologies to enable crops to store more carbon and energy, with the goal of increasing yields in biomass and fruit. The approach also enhances crop resilience to extreme weather, supporting climate adaptation and more reliable production for agricultural companies. Founded in 2021 and based in Ness Ziona, the company focuses on leveraging plant energy capture to boost productivity.

UPSIDE Foods

Series C in 2022
UPSIDE Foods, formerly known as Memphis Meats, is a cultivated meat company founded in 2015 and headquartered in Berkeley, California. The company specializes in producing real meat, poultry, and seafood directly from animal cells, eliminating the need to raise and slaughter animals. This innovative approach significantly reduces the resource consumption associated with traditional meat production, requiring less water, land, and energy. UPSIDE Foods aims to offer consumers clean, humane, and sustainable meat products, such as beef meatballs, chicken, and duck, all grown in controlled environments. The company is led by Dr. Uma Valeti, who is committed to transforming the food industry with healthier and environmentally friendly alternatives to conventional meat.

Innatrix

Convertible Note in 2022
Innatrix is an agricultural biotechnology company focused on developing innovative biological and chemical solutions to address crop diseases, pests, and weeds that are otherwise difficult to manage. Utilizing patented protein evolution technology, the company has established a peptide and RNA interference delivery platform that offers eco-friendly alternatives for crop protection. Innatrix's proprietary automated platform facilitates protein engineering through continuous laboratory evolution and advanced techniques such as phage display. This technology empowers researchers with enhanced control, reporting, recording, simulation, and remote access capabilities, thereby advancing the field of agricultural biotechnology and promoting sustainable farming practices.

Innatrix

Seed Round in 2022
Innatrix is an agricultural biotechnology company focused on developing innovative biological and chemical solutions to address crop diseases, pests, and weeds that are otherwise difficult to manage. Utilizing patented protein evolution technology, the company has established a peptide and RNA interference delivery platform that offers eco-friendly alternatives for crop protection. Innatrix's proprietary automated platform facilitates protein engineering through continuous laboratory evolution and advanced techniques such as phage display. This technology empowers researchers with enhanced control, reporting, recording, simulation, and remote access capabilities, thereby advancing the field of agricultural biotechnology and promoting sustainable farming practices.

Ceragen

Convertible Note in 2022
Ceragen is a biotechnology company that helps farmers increase crop yields through plant microbiome engineering. It develops precision microbiome engineering via inoculant products tailored for controlled environment agriculture, enabling crops to respond to environmental stress and to produce more in limited space with an all-natural solution. Ceragen was established in Kitchener, Ontario.

ClimateCrop

Seed Round in 2021
ClimateCrop develops gene editing and related plant technologies to enable crops to store more carbon and energy, with the goal of increasing yields in biomass and fruit. The approach also enhances crop resilience to extreme weather, supporting climate adaptation and more reliable production for agricultural companies. Founded in 2021 and based in Ness Ziona, the company focuses on leveraging plant energy capture to boost productivity.

ClimateCrop

Convertible Note in 2021
ClimateCrop develops gene editing and related plant technologies to enable crops to store more carbon and energy, with the goal of increasing yields in biomass and fruit. The approach also enhances crop resilience to extreme weather, supporting climate adaptation and more reliable production for agricultural companies. Founded in 2021 and based in Ness Ziona, the company focuses on leveraging plant energy capture to boost productivity.

California Cultured

Seed Round in 2021
California Cultured is a food company that uses cellular agriculture to produce cocoa and coffee, with the aim of delivering sustainable, lab-grown ingredients. Its cocoa is described as less bitter and requiring less sugar to achieve flavor, enabling premium quality products with a smaller environmental footprint. The company seeks to address social and environmental concerns linked to traditional cocoa production by avoiding practices such as slavery, deforestation, and child labor. California Cultured was founded in 2020 and is based in Davis, California.

Puna Bio

Convertible Note in 2021
Puna Bio specializes in developing biological products for the agricultural sector. Based in Buenos Aires, Argentina, the company focuses on enhancing crop nutrition using extremophile microorganisms, aiming to improve yields and soil quality sustainably.

Ceragen

Convertible Note in 2021
Ceragen is a biotechnology company that helps farmers increase crop yields through plant microbiome engineering. It develops precision microbiome engineering via inoculant products tailored for controlled environment agriculture, enabling crops to respond to environmental stress and to produce more in limited space with an all-natural solution. Ceragen was established in Kitchener, Ontario.

Ceragen

Seed Round in 2021
Ceragen is a biotechnology company that helps farmers increase crop yields through plant microbiome engineering. It develops precision microbiome engineering via inoculant products tailored for controlled environment agriculture, enabling crops to respond to environmental stress and to produce more in limited space with an all-natural solution. Ceragen was established in Kitchener, Ontario.

California Cultured

Seed Round in 2021
California Cultured is a food company that uses cellular agriculture to produce cocoa and coffee, with the aim of delivering sustainable, lab-grown ingredients. Its cocoa is described as less bitter and requiring less sugar to achieve flavor, enabling premium quality products with a smaller environmental footprint. The company seeks to address social and environmental concerns linked to traditional cocoa production by avoiding practices such as slavery, deforestation, and child labor. California Cultured was founded in 2020 and is based in Davis, California.

Reazent

Convertible Note in 2020
Reazent is an agricultural technology company focused on developing safe, natural, biologically based alternatives to agrochemicals. Founded in 2018 and based in Halifax, Canada, it seeks to replace synthetic agrochemicals with sustainable, economically viable solutions. The company develops products that support crop growth, yield, and stress resistance, addressing diseases such as bacterial soft rot, Phytophthora blight, and anthracnose in leafy fruits and vegetables, enabling farmers to improve crop health and return on investment through safer disease control and abiotic stress resilience.

Reazent

Seed Round in 2020
Reazent is an agricultural technology company focused on developing safe, natural, biologically based alternatives to agrochemicals. Founded in 2018 and based in Halifax, Canada, it seeks to replace synthetic agrochemicals with sustainable, economically viable solutions. The company develops products that support crop growth, yield, and stress resistance, addressing diseases such as bacterial soft rot, Phytophthora blight, and anthracnose in leafy fruits and vegetables, enabling farmers to improve crop health and return on investment through safer disease control and abiotic stress resilience.

Reazent

Seed Round in 2020
Reazent is an agricultural technology company focused on developing safe, natural, biologically based alternatives to agrochemicals. Founded in 2018 and based in Halifax, Canada, it seeks to replace synthetic agrochemicals with sustainable, economically viable solutions. The company develops products that support crop growth, yield, and stress resistance, addressing diseases such as bacterial soft rot, Phytophthora blight, and anthracnose in leafy fruits and vegetables, enabling farmers to improve crop health and return on investment through safer disease control and abiotic stress resilience.

UPSIDE Foods

Series B in 2020
UPSIDE Foods, formerly known as Memphis Meats, is a cultivated meat company founded in 2015 and headquartered in Berkeley, California. The company specializes in producing real meat, poultry, and seafood directly from animal cells, eliminating the need to raise and slaughter animals. This innovative approach significantly reduces the resource consumption associated with traditional meat production, requiring less water, land, and energy. UPSIDE Foods aims to offer consumers clean, humane, and sustainable meat products, such as beef meatballs, chicken, and duck, all grown in controlled environments. The company is led by Dr. Uma Valeti, who is committed to transforming the food industry with healthier and environmentally friendly alternatives to conventional meat.

Calyx

Seed Round in 2018
Calyx develops advanced sensor platforms that monitor various parameters in poultry farming with exceptional specificity and sensitivity. The company combines AI computer vision technology, bio-engineered sensors, and data science to address complex challenges in the poultry industry.

SmartShepherd

Seed Round in 2017
SmartShepherd, founded in 2017 and headquartered in Armidale, Australia with a manufacturing facility in Shenzhen, China, specializes in designing and producing wearable devices for collecting pedigree data in the livestock industry. The company's products include smart tags and the SmartShepherd system, which utilize low-cost Bluetooth technology and an IoT architecture to make full pedigree recording more accessible. This solution empowers farmers to enhance their breeding practices by providing detailed data on livestock genetics, thereby improving productivity and reducing inbreeding.

SmartShepherd

Convertible Note in 2017
SmartShepherd, founded in 2017 and headquartered in Armidale, Australia with a manufacturing facility in Shenzhen, China, specializes in designing and producing wearable devices for collecting pedigree data in the livestock industry. The company's products include smart tags and the SmartShepherd system, which utilize low-cost Bluetooth technology and an IoT architecture to make full pedigree recording more accessible. This solution empowers farmers to enhance their breeding practices by providing detailed data on livestock genetics, thereby improving productivity and reducing inbreeding.

UPSIDE Foods

Seed Round in 2016
UPSIDE Foods, formerly known as Memphis Meats, is a cultivated meat company founded in 2015 and headquartered in Berkeley, California. The company specializes in producing real meat, poultry, and seafood directly from animal cells, eliminating the need to raise and slaughter animals. This innovative approach significantly reduces the resource consumption associated with traditional meat production, requiring less water, land, and energy. UPSIDE Foods aims to offer consumers clean, humane, and sustainable meat products, such as beef meatballs, chicken, and duck, all grown in controlled environments. The company is led by Dr. Uma Valeti, who is committed to transforming the food industry with healthier and environmentally friendly alternatives to conventional meat.

Endura Bio

Seed Round in 2016
Endura Bio, Inc. is a biotechnology company based in Sunnyvale, California, focused on developing solutions to enhance plant growth while minimizing water usage. Incorporated in 2016, the company offers ClimateGuard, a proprietary blend of enzymes designed to reduce water requirements in crops, which can be applied through traditional irrigation or as a soil amendment. This product aims to prevent yield loss by addressing oxidative stress and water imbalance in plants. Additionally, Endura Bio is engaged in engineering salt and drought-tolerant plants, addressing the challenges posed by salt groundwater contamination and arid environments. By improving the resilience of crops grown on marginal lands, Endura Bio seeks to contribute to global food security.

Genome Surveillance

Seed Round in 2016
Genome Surveillance is a pioneering company focused on advancing DNA sequencing technologies to enhance speed and accuracy in genomic analysis. By utilizing innovative scaffold sequencing methods, Genome Surveillance addresses the challenges of high computational costs and inaccuracies associated with traditional sequencing approaches. The company's technology enables medical researchers to efficiently obtain reliable genomic information, facilitating genome reconstruction, structural variation discovery, molecular marker development, and agricultural research. By significantly reducing both the time and cost of sequencing, Genome Surveillance is positioned to meet the growing demand for precise genomic data in various scientific fields.

UPSIDE Foods

Seed Round in 2015
UPSIDE Foods, formerly known as Memphis Meats, is a cultivated meat company founded in 2015 and headquartered in Berkeley, California. The company specializes in producing real meat, poultry, and seafood directly from animal cells, eliminating the need to raise and slaughter animals. This innovative approach significantly reduces the resource consumption associated with traditional meat production, requiring less water, land, and energy. UPSIDE Foods aims to offer consumers clean, humane, and sustainable meat products, such as beef meatballs, chicken, and duck, all grown in controlled environments. The company is led by Dr. Uma Valeti, who is committed to transforming the food industry with healthier and environmentally friendly alternatives to conventional meat.

DTOR

Pre Seed Round in 2015
At DtoR they have developed the PCR of gene expression—a disruptive technology that will revolutionize the tools used to “tune” protein production in any organism. In one step, and for any cell type, they can identify all of the switches regulating expression of the genome, as well as how active they are. They can also rapidly evolve or synthesize new switches to adapt to any application. Applications developed using their platform will lead to improved product yields in bioreactors, engineered specialty crops, optimized cancer therapeutics, and much more. The possibilities are limited only by their partners' imaginations.
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