General Catalyst

Aura is an information technology company dedicated to creating a safer internet for everyone. People are doing more online than ever, but as our lives get more connected, it's hard to know what’s safe. Aura believes people should be able to live their digital lives with peace of mind. Its mission is to create a safer internet by making comprehensive digital security simple to understand and easy to use so everyone can stay safe online.

Ramp is a company that specializes in providing modern solutions for financial operations and enterprise content delivery. Its financial platform includes tools for corporate card management, expense tracking, bill payments, and seamless accounting integrations, aimed at helping organizations optimize their financial tasks and reduce costs. Additionally, Ramp offers advanced video management and delivery software, enabling companies to enhance video content discovery, user engagement, and secure delivery. Its products, such as VideoVerge and AltitudeCDN, leverage innovative technologies like speech-to-text and natural language processing to create rich metadata for video assets, allowing them to be effectively integrated into popular content management systems. Ramp serves a diverse clientele, including prominent media companies and organizations across various industries such as healthcare, finance, and technology. Founded in 1948 and based in Boston, Massachusetts, Ramp operates as a subsidiary of Raytheon BBN Technologies Corporation.

Overjet, Inc. specializes in developing artificial intelligence (AI) software aimed at enhancing dental care. Founded by experts from MIT and Harvard, the company produces clinical optimization and utilization software that analyzes dental clinical data to assess practice performance and identify growth opportunities. Its AI technology is designed to automatically review claims, highlighting instances of over and underutilization to ensure appropriate care at reduced costs. Overjet's FDA-cleared platform is the first objective standard for oral health decision-making, enabling dentists to detect pathologies accurately and communicate effectively with patients. Established in 2018, Overjet is headquartered in Allston, Massachusetts.

Eleanor Health is a provider of addiction and mental health services focused on delivering long-term recovery outcomes through a value-based care model. Established in 2019 and headquartered in Waltham, Massachusetts, Eleanor Health offers comprehensive, whole-person care for mental health and substance misuse. Its services include evidence-based outpatient care, medication-assisted treatment for addiction, and personalized recovery plans, which are delivered through a network of outpatient clinics, virtually, and in community and home settings. This integrated approach aims to expedite the recovery process for individuals suffering from substance use disorders.

Commure, Inc. is a technology company that develops an open platform aimed at healthcare software developers, enabling the creation and deployment of advanced healthcare applications. The platform is built on the open HL7 FHIR standard and offers various features, including an FHIR API server, security framework, event service bus, EHR integration, and a flexible data store. Commure's solutions facilitate the unification of disparate datasets, providing meaningful insights and enhancing performance through intuitive applications. The company collaborates with health systems, digital innovators, and payors to foster a vibrant healthcare ecosystem, ultimately empowering clinicians and staff to improve patient care. Established in 2017, Commure is headquartered in San Francisco, California, with additional offices in Boston, Montreal, and Bogota.

Cartwheel offers mental health support to students in order to help schools regain balance in the midst of the student mental health crisis. It works hand in hand to empower school staff, reduce family stress, and improve all students' mental health outcomes. Its FERPA- and HIPAA-compliant program is built specifically for schools and their unique needs in the wake of the COVID-19 pandemic. Cartwheel was founded in 2022 and is based in Cambridge, Massachusetts.

Zageno Inc. is an online retailer specializing in life science research products, aiming to streamline the purchasing process for researchers globally. Founded in 2015 and headquartered in Cambridge, Massachusetts, Zageno offers a diverse range of over 10 million products, including preparation items, gene editing tools, PCR products, sequencing kits, and various detection and lab accessories. The company features a unique Scientific Score, which provides unbiased, peer-reviewed ratings to assist customers in making informed purchasing decisions. Zageno's platform is designed to enhance convenience and efficiency in acquiring research materials, serving as a reliable sales channel for suppliers and partners in the biotechnology sector. The company also has an office in Berlin, Germany, reflecting its commitment to fostering scientific innovation.

Fractyl Health, based in Lexington, Massachusetts, specializes in developing innovative medical device solutions for metabolic diseases, particularly type 2 diabetes and obesity. The company’s primary offering, Revita DMR, is a minimally invasive therapy that utilizes hydrothermal ablation to rejuvenate the duodenal lining, which can become compromised due to high-fat and high-sugar diets. By focusing on durable disease-modifying therapies rather than just symptomatic management, Fractyl Health aims to address the underlying causes of metabolic diseases, improving patient outcomes and reducing healthcare burdens. Founded in 2010 and originally named MedCatalyst, Inc., the company envisions a future where less invasive, device-based therapies provide effective solutions for large populations affected by metabolic disorders.

Eleanor Health is a provider of addiction and mental health services focused on delivering long-term recovery outcomes through a value-based care model. Established in 2019 and headquartered in Waltham, Massachusetts, Eleanor Health offers comprehensive, whole-person care for mental health and substance misuse. Its services include evidence-based outpatient care, medication-assisted treatment for addiction, and personalized recovery plans, which are delivered through a network of outpatient clinics, virtually, and in community and home settings. This integrated approach aims to expedite the recovery process for individuals suffering from substance use disorders.

Avant-garde Health, Inc. is a healthcare solutions company based in Allston, Massachusetts, founded in 2014. It specializes in developing a web-based analytics platform that assists hospitals and healthcare providers in analyzing and comparing their costs and outcomes in care delivery. The platform measures the costs of various care processes and evaluates treatment-specific data, enabling providers to learn from peer institutions and enhance their results. Avant-garde Health partners with leading healthcare providers committed to improving the value of care, offering actionable insights that facilitate better clinical decision-making and promote value-based payment models. The company was inspired by research on value-based healthcare delivery conducted at Harvard Business School.

Dewpoint Therapeutics is a Boston-based biotech company focused on the research and development of treatments targeting biomolecular condensates to address various diseases, including cancer, neurodegenerative disorders, and immunological conditions. Founded in 2018, the company employs an innovative drug platform that utilizes machine-learning-based image analysis for visualizing condensates. This technology supports an engine of engineered cell lines designed to track and mitigate harmful protein sequestration. By leveraging its proprietary platform, Dewpoint seeks to facilitate drug discovery across a wide range of medical indications and collaborates with leading academic and pharmaceutical partners to enhance the accessibility of new therapies for unmet healthcare needs.

Superpedestrian, Inc. is a robotics company based in Cambridge, Massachusetts, that specializes in developing lightweight electric vehicles designed for eco-friendly transportation. The company’s flagship product, the Copenhagen Wheel, integrates advanced technology to enhance cycling safety and wellness, while also offering a platform for developers to create various applications. These applications range from navigation assistance to customization of the wheel's behavior. Superpedestrian sells its products through both retail channels and online platforms. Founded in 2012, the company aims to provide a comfortable and secure cycling experience by utilizing vehicle intelligence to monitor and address potential malfunctions proactively.

Superpedestrian, Inc. is a robotics company based in Cambridge, Massachusetts, that specializes in developing lightweight electric vehicles designed for eco-friendly transportation. The company’s flagship product, the Copenhagen Wheel, integrates advanced technology to enhance cycling safety and wellness, while also offering a platform for developers to create various applications. These applications range from navigation assistance to customization of the wheel's behavior. Superpedestrian sells its products through both retail channels and online platforms. Founded in 2012, the company aims to provide a comfortable and secure cycling experience by utilizing vehicle intelligence to monitor and address potential malfunctions proactively.

Overjet, Inc. specializes in developing artificial intelligence (AI) software aimed at enhancing dental care. Founded by experts from MIT and Harvard, the company produces clinical optimization and utilization software that analyzes dental clinical data to assess practice performance and identify growth opportunities. Its AI technology is designed to automatically review claims, highlighting instances of over and underutilization to ensure appropriate care at reduced costs. Overjet's FDA-cleared platform is the first objective standard for oral health decision-making, enabling dentists to detect pathologies accurately and communicate effectively with patients. Established in 2018, Overjet is headquartered in Allston, Massachusetts.

Well Dot, Inc. is a health technology company that has developed an artificial intelligence-based consumer health engagement platform and mobile application. Founded in 2019 and headquartered in Chapel Hill, North Carolina, with additional offices in Massachusetts, New York, and Minnesota, Well's platform uses clinical and consumer data to offer personalized health guidance and support. It analyzes individual health triggers to promote tailored, achievable steps for members to improve their health. The platform is designed to engage, educate, and empower users, providing easy-to-understand explanations and active assistance from health teams. By focusing on creating a meaningful and personalized health journey, Well aims to motivate individuals to adopt healthier habits and achieve better health outcomes.

Hometap is a fintech company founded in 2018 and based in Boston, Massachusetts, that specializes in home equity investments. It offers homeowners a unique opportunity to access cash without incurring debt or selling their property. By providing immediate funds in exchange for a percentage of the home's future value, Hometap enables homeowners to utilize the money for various purposes, such as paying off debt or financing renovations. This approach allows homeowners to improve their financial situation without the burden of monthly payments or additional loans.

Zageno Inc. is an online retailer specializing in life science research products, aiming to streamline the purchasing process for researchers globally. Founded in 2015 and headquartered in Cambridge, Massachusetts, Zageno offers a diverse range of over 10 million products, including preparation items, gene editing tools, PCR products, sequencing kits, and various detection and lab accessories. The company features a unique Scientific Score, which provides unbiased, peer-reviewed ratings to assist customers in making informed purchasing decisions. Zageno's platform is designed to enhance convenience and efficiency in acquiring research materials, serving as a reliable sales channel for suppliers and partners in the biotechnology sector. The company also has an office in Berlin, Germany, reflecting its commitment to fostering scientific innovation.

Aura is an information technology company dedicated to creating a safer internet for everyone. People are doing more online than ever, but as our lives get more connected, it's hard to know what’s safe. Aura believes people should be able to live their digital lives with peace of mind. Its mission is to create a safer internet by making comprehensive digital security simple to understand and easy to use so everyone can stay safe online.

Overjet, Inc. specializes in developing artificial intelligence (AI) software aimed at enhancing dental care. Founded by experts from MIT and Harvard, the company produces clinical optimization and utilization software that analyzes dental clinical data to assess practice performance and identify growth opportunities. Its AI technology is designed to automatically review claims, highlighting instances of over and underutilization to ensure appropriate care at reduced costs. Overjet's FDA-cleared platform is the first objective standard for oral health decision-making, enabling dentists to detect pathologies accurately and communicate effectively with patients. Established in 2018, Overjet is headquartered in Allston, Massachusetts.

JuliaHub is a platform that facilitates modeling, simulation, and the development of user-built applications, primarily targeting scientists, engineers, and innovators. Established in 2015 by Viral Shah in Cambridge, Massachusetts, JuliaHub provides high-performance computing capabilities that enable users to bring their innovative ideas to fruition at any scale. The platform supports the open-source Julia programming language, which is designed to simplify programming tasks related to data science, machine learning, and scientific computing. This includes applications in research, backtesting, trading, and contract modeling. With features that emphasize ease of use and an intuitive syntax, JuliaHub enhances the user experience while maintaining robust performance for complex data analysis and computations.

OM1, Inc. is a digital health company that specializes in developing a platform for healthcare organizations to measure and forecast patient outcomes. The platform is designed to assist hospitals, health systems, and other healthcare providers in meeting various patient reported and clinical outcomes requirements for value-based care programs. By leveraging advanced predictive and prescriptive analytics, OM1 aims to mitigate risks, lower costs, and enhance the understanding of treatment outcomes across the care continuum. The company's technology gathers and synthesizes clinical data to provide AI-driven insights, enabling healthcare organizations to analyze and utilize outcomes data effectively. Founded in 2014 and based in Boston, Massachusetts, OM1 was previously known as Better Outcomes Corporation.

NewStore, Inc. is a technology company that offers an Omnichannel-as-a-Service platform designed for retailers to enhance their operations and customer engagement. The platform facilitates mobile commerce through an integrated cloud order management system and mobile point of sale, enabling seamless shopping experiences such as endless aisle access, mobile checkout, and real-time inventory management. NewStore allows brands to create a unified experience by connecting consumers, stores, and sales associates, thereby fostering innovation in retail. The company provides valuable insights into various aspects of retail operations, including store health and performance tracking, which helps retailers optimize their strategies. Founded in 2012 and based in Boston, Massachusetts, NewStore also has offices in New York and Germany. It was originally known as GoodsCloud Inc. before rebranding in 2015.

PathAI, Inc. is a company that develops artificial intelligence-based technology solutions aimed at enhancing the accuracy and efficiency of pathology laboratories. Founded in 2016 and headquartered in Boston, Massachusetts, with an additional office in Austin, Texas, PathAI's platform utilizes machine and deep learning techniques to process large datasets, enabling pathologists to diagnose cancer and other conditions rapidly and accurately. The technology not only assists in making precise diagnoses but also identifies patients who may benefit from innovative therapies, thereby facilitating personalized medicine. PathAI addresses complex challenges in pathology for both the research and pharmaceutical industries, providing reliable and scalable solutions.

Alyce is an AI-powered platform that works as a door-opener or to continue to develop real sales relationships. The platform redefining direct mail, swag and gifts with its scalable, sustainable, hyper-personalized approach to account-based marketing. It uses personal social data to tell you the perfect gift to give and handles orders, shipping, and reporting for 1-10,000 gifts, and is 100% free. Alyce builds real, personal relationships that deliver up to twice the named account penetration and drives 5x pipeline versus traditional approaches. It makes B2B gift-giving simple, effective and measurable. The company was founded in December of 2015, Alyce is a privately held company headquartered in Boston, MA.

airSlate, Inc. is a technology company based in Brookline, Massachusetts, that specializes in workflow automation and document management solutions. Founded in 2006, the company provides a range of no-code tools, including document generation, contract negotiation, and robotic process automation. Its offerings also include electronic signature solutions, customizable web forms, and comprehensive workflow automation software designed to streamline document processes across various industries such as finance, human resources, legal, and marketing. airSlate's products, which include pdfFiller, signNow, and USLegal, integrate with major platforms like Salesforce and Microsoft Dynamics 365, allowing users to enhance operational efficiency and improve employee satisfaction. Additionally, the company offers online certification programs focused on automation. Formerly known as PDFfiler, airSlate rebranded in January 2019 to reflect its expanded capabilities in the digital transformation space.

TowerIQ is a broker first platform that brings transparency to insurance markets. The company seamlessly brings clients from application to binding by augmenting broker expertise with a low touch technology platform that distributes ingestible data directly to any carrier. This frees brokers and agents to focus their efforts on solving the business challenges facing the clients that allow them to win more business and improve client retention. TowerIQ was founded in 2017 and is headquartered in Boston, Massachusetts.

Superpedestrian, Inc. is a robotics company based in Cambridge, Massachusetts, that specializes in developing lightweight electric vehicles designed for eco-friendly transportation. The company’s flagship product, the Copenhagen Wheel, integrates advanced technology to enhance cycling safety and wellness, while also offering a platform for developers to create various applications. These applications range from navigation assistance to customization of the wheel's behavior. Superpedestrian sells its products through both retail channels and online platforms. Founded in 2012, the company aims to provide a comfortable and secure cycling experience by utilizing vehicle intelligence to monitor and address potential malfunctions proactively.

Catalant is a software company that offers a platform designed to connect global enterprises with business expertise on demand. The company supports over 30% of the Fortune 100 in accelerating their strategy execution through its innovative software solutions. Catalant's platform allows businesses to define their strategic objectives, break them down into actionable elements, and access both internal and external resources for execution. With a network of more than 65,000 experts and 1,000 firms, the platform facilitates collaboration and measures the value of work undertaken. Additionally, Catalant provides tools to manage this network efficiently. Headquartered in Boston, Massachusetts, the company serves clients worldwide, including private equity firms seeking to connect with qualified business professionals.

Evolv Technology specializes in AI-based touchless security screening systems that prioritize safety while enhancing the visitor experience. The company's Mosaiq Platform integrates real-time video surveillance with advanced detection capabilities for firearms and explosives, facial recognition, and security analytics, all designed to minimize false alarms. Headquartered in Waltham, Massachusetts, Evolv is led by professionals with extensive backgrounds in security, including experience with the TSA, FBI, CIA, Secret Service, and Homeland Security. The firm offers its products through direct sales and a multi-year security-as-a-service subscription model, which not only provides ongoing value to clients but also fosters predictable revenue streams and opportunities for expansion. Evolv Technology aims to protect both public and private sectors by securing soft targets and vital assets.

Evolv Technology specializes in AI-based touchless security screening systems that prioritize safety while enhancing the visitor experience. The company's Mosaiq Platform integrates real-time video surveillance with advanced detection capabilities for firearms and explosives, facial recognition, and security analytics, all designed to minimize false alarms. Headquartered in Waltham, Massachusetts, Evolv is led by professionals with extensive backgrounds in security, including experience with the TSA, FBI, CIA, Secret Service, and Homeland Security. The firm offers its products through direct sales and a multi-year security-as-a-service subscription model, which not only provides ongoing value to clients but also fosters predictable revenue streams and opportunities for expansion. Evolv Technology aims to protect both public and private sectors by securing soft targets and vital assets.

Aura is an information technology company dedicated to creating a safer internet for everyone. People are doing more online than ever, but as our lives get more connected, it's hard to know what’s safe. Aura believes people should be able to live their digital lives with peace of mind. Its mission is to create a safer internet by making comprehensive digital security simple to understand and easy to use so everyone can stay safe online.

Alyce is an AI-powered platform that works as a door-opener or to continue to develop real sales relationships. The platform redefining direct mail, swag and gifts with its scalable, sustainable, hyper-personalized approach to account-based marketing. It uses personal social data to tell you the perfect gift to give and handles orders, shipping, and reporting for 1-10,000 gifts, and is 100% free. Alyce builds real, personal relationships that deliver up to twice the named account penetration and drives 5x pipeline versus traditional approaches. It makes B2B gift-giving simple, effective and measurable. The company was founded in December of 2015, Alyce is a privately held company headquartered in Boston, MA.

Well Dot, Inc. is a health technology company that has developed an artificial intelligence-based consumer health engagement platform and mobile application. Founded in 2019 and headquartered in Chapel Hill, North Carolina, with additional offices in Massachusetts, New York, and Minnesota, Well's platform uses clinical and consumer data to offer personalized health guidance and support. It analyzes individual health triggers to promote tailored, achievable steps for members to improve their health. The platform is designed to engage, educate, and empower users, providing easy-to-understand explanations and active assistance from health teams. By focusing on creating a meaningful and personalized health journey, Well aims to motivate individuals to adopt healthier habits and achieve better health outcomes.

Zageno Inc. is an online retailer specializing in life science research products, aiming to streamline the purchasing process for researchers globally. Founded in 2015 and headquartered in Cambridge, Massachusetts, Zageno offers a diverse range of over 10 million products, including preparation items, gene editing tools, PCR products, sequencing kits, and various detection and lab accessories. The company features a unique Scientific Score, which provides unbiased, peer-reviewed ratings to assist customers in making informed purchasing decisions. Zageno's platform is designed to enhance convenience and efficiency in acquiring research materials, serving as a reliable sales channel for suppliers and partners in the biotechnology sector. The company also has an office in Berlin, Germany, reflecting its commitment to fostering scientific innovation.

PathAI, Inc. is a company that develops artificial intelligence-based technology solutions aimed at enhancing the accuracy and efficiency of pathology laboratories. Founded in 2016 and headquartered in Boston, Massachusetts, with an additional office in Austin, Texas, PathAI's platform utilizes machine and deep learning techniques to process large datasets, enabling pathologists to diagnose cancer and other conditions rapidly and accurately. The technology not only assists in making precise diagnoses but also identifies patients who may benefit from innovative therapies, thereby facilitating personalized medicine. PathAI addresses complex challenges in pathology for both the research and pharmaceutical industries, providing reliable and scalable solutions.

Lola.com is an easy-to-use travel management tool that helps companies book, report, and save on business travel. Life becomes simpler with employee friendly business travel policies, fun travel tracking tools, and transparent spend reporting for business travel managers. For the business travelers, it enables easy flight and hotel booking, team destination sharing, loyalty points from the actual hotels and airlines, and 24/7 agent support. Its book on behalf feature lets executive assistants, easily book travel like a boss. Founded on 2015, Lola.com works for both employers and employees. It is headquartered in Boston, Massachusetts.

Yottaa, Inc. is a cloud-based company that specializes in optimizing eCommerce experiences for brands and retailers. Founded in 2009 and based in Boston, Massachusetts, with an additional office in Beijing, Yottaa offers a range of solutions designed to enhance online consumer engagement. Its key products include InstantON, which accelerates page rendering to capture user attention, and AppSequencing, which prioritizes application elements for improved user interaction. The Rapid CTRL software enables online retailers to manage third-party applications effectively, while ImpactAnalytics provides insights on the return on investment from application optimization. Additionally, ContextIntelligence automates the contextual optimization of online and mobile applications. Yottaa serves a diverse clientele, including Internet retailers and Fortune 500 companies, helping them achieve faster, more secure, and efficient online interactions that drive conversions and enhance customer satisfaction. The company is trusted by over 1,500 leading sites, significantly boosting site speed and improving the overall shopper journey.

Allego, Inc. is a provider of a mobile-first sales learning platform that enhances workforce performance through mobile, video, and peer learning. Founded in 2013 and based in Needham, Massachusetts, Allego's flagship product includes a comprehensive sales learning platform designed specifically for sales teams. It facilitates various forms of learning, such as curriculum-based, just-in-time, and reinforcement learning, while also offering tools for knowledge assessment, sequenced learning paths, and video-based coaching. Allego's platform supports quicker employee onboarding and timely sales coaching, catering to industries such as high technology, financial services, medical devices, and pharmaceuticals. The platform is accessible via mobile devices and browsers, allowing hybrid sales teams to efficiently manage and activate content, ultimately driving improved sales performance and engagement with buyers. The company is recognized as a trusted partner for numerous leading global enterprises.

Superpedestrian, Inc. is a robotics company based in Cambridge, Massachusetts, that specializes in developing lightweight electric vehicles designed for eco-friendly transportation. The company’s flagship product, the Copenhagen Wheel, integrates advanced technology to enhance cycling safety and wellness, while also offering a platform for developers to create various applications. These applications range from navigation assistance to customization of the wheel's behavior. Superpedestrian sells its products through both retail channels and online platforms. Founded in 2012, the company aims to provide a comfortable and secure cycling experience by utilizing vehicle intelligence to monitor and address potential malfunctions proactively.

OM1, Inc. is a digital health company that specializes in developing a platform for healthcare organizations to measure and forecast patient outcomes. The platform is designed to assist hospitals, health systems, and other healthcare providers in meeting various patient reported and clinical outcomes requirements for value-based care programs. By leveraging advanced predictive and prescriptive analytics, OM1 aims to mitigate risks, lower costs, and enhance the understanding of treatment outcomes across the care continuum. The company's technology gathers and synthesizes clinical data to provide AI-driven insights, enabling healthcare organizations to analyze and utilize outcomes data effectively. Founded in 2014 and based in Boston, Massachusetts, OM1 was previously known as Better Outcomes Corporation.

NewStore, Inc. is a technology company that offers an Omnichannel-as-a-Service platform designed for retailers to enhance their operations and customer engagement. The platform facilitates mobile commerce through an integrated cloud order management system and mobile point of sale, enabling seamless shopping experiences such as endless aisle access, mobile checkout, and real-time inventory management. NewStore allows brands to create a unified experience by connecting consumers, stores, and sales associates, thereby fostering innovation in retail. The company provides valuable insights into various aspects of retail operations, including store health and performance tracking, which helps retailers optimize their strategies. Founded in 2012 and based in Boston, Massachusetts, NewStore also has offices in New York and Germany. It was originally known as GoodsCloud Inc. before rebranding in 2015.

Circle is a financial technology firm that leverages blockchain technology and stablecoins to facilitate payments and e-commerce. Founded in 2013 by Jeremy Allaire and Sean Neville, Circle enhances the way users send and receive money through its platform, Circle Pay. The company offers a cryptocurrency investment product called Circle Invest, enabling users to buy and sell various crypto assets. Additionally, Circle provides over-the-counter trading services through Circle Trade, featuring one of the largest global liquidity pools for digital asset trading, with an average monthly volume of $2 billion. Backed by significant investments from notable firms, Circle operates from its headquarters in Boston and has branches in New York, San Francisco, Dublin, London, and Hong Kong.

Hometap is a fintech company founded in 2018 and based in Boston, Massachusetts, that specializes in home equity investments. It offers homeowners a unique opportunity to access cash without incurring debt or selling their property. By providing immediate funds in exchange for a percentage of the home's future value, Hometap enables homeowners to utilize the money for various purposes, such as paying off debt or financing renovations. This approach allows homeowners to improve their financial situation without the burden of monthly payments or additional loans.

Avant-garde Health, Inc. is a healthcare solutions company based in Allston, Massachusetts, founded in 2014. It specializes in developing a web-based analytics platform that assists hospitals and healthcare providers in analyzing and comparing their costs and outcomes in care delivery. The platform measures the costs of various care processes and evaluates treatment-specific data, enabling providers to learn from peer institutions and enhance their results. Avant-garde Health partners with leading healthcare providers committed to improving the value of care, offering actionable insights that facilitate better clinical decision-making and promote value-based payment models. The company was inspired by research on value-based healthcare delivery conducted at Harvard Business School.

Fractyl Health, based in Lexington, Massachusetts, specializes in developing innovative medical device solutions for metabolic diseases, particularly type 2 diabetes and obesity. The company’s primary offering, Revita DMR, is a minimally invasive therapy that utilizes hydrothermal ablation to rejuvenate the duodenal lining, which can become compromised due to high-fat and high-sugar diets. By focusing on durable disease-modifying therapies rather than just symptomatic management, Fractyl Health aims to address the underlying causes of metabolic diseases, improving patient outcomes and reducing healthcare burdens. Founded in 2010 and originally named MedCatalyst, Inc., the company envisions a future where less invasive, device-based therapies provide effective solutions for large populations affected by metabolic disorders.

PathAI, Inc. is a company that develops artificial intelligence-based technology solutions aimed at enhancing the accuracy and efficiency of pathology laboratories. Founded in 2016 and headquartered in Boston, Massachusetts, with an additional office in Austin, Texas, PathAI's platform utilizes machine and deep learning techniques to process large datasets, enabling pathologists to diagnose cancer and other conditions rapidly and accurately. The technology not only assists in making precise diagnoses but also identifies patients who may benefit from innovative therapies, thereby facilitating personalized medicine. PathAI addresses complex challenges in pathology for both the research and pharmaceutical industries, providing reliable and scalable solutions.

Alyce is an AI-powered platform that works as a door-opener or to continue to develop real sales relationships. The platform redefining direct mail, swag and gifts with its scalable, sustainable, hyper-personalized approach to account-based marketing. It uses personal social data to tell you the perfect gift to give and handles orders, shipping, and reporting for 1-10,000 gifts, and is 100% free. Alyce builds real, personal relationships that deliver up to twice the named account penetration and drives 5x pipeline versus traditional approaches. It makes B2B gift-giving simple, effective and measurable. The company was founded in December of 2015, Alyce is a privately held company headquartered in Boston, MA.

Commure, Inc. is a technology company that develops an open platform aimed at healthcare software developers, enabling the creation and deployment of advanced healthcare applications. The platform is built on the open HL7 FHIR standard and offers various features, including an FHIR API server, security framework, event service bus, EHR integration, and a flexible data store. Commure's solutions facilitate the unification of disparate datasets, providing meaningful insights and enhancing performance through intuitive applications. The company collaborates with health systems, digital innovators, and payors to foster a vibrant healthcare ecosystem, ultimately empowering clinicians and staff to improve patient care. Established in 2017, Commure is headquartered in San Francisco, California, with additional offices in Boston, Montreal, and Bogota.

NewStore, Inc. is a technology company that offers an Omnichannel-as-a-Service platform designed for retailers to enhance their operations and customer engagement. The platform facilitates mobile commerce through an integrated cloud order management system and mobile point of sale, enabling seamless shopping experiences such as endless aisle access, mobile checkout, and real-time inventory management. NewStore allows brands to create a unified experience by connecting consumers, stores, and sales associates, thereby fostering innovation in retail. The company provides valuable insights into various aspects of retail operations, including store health and performance tracking, which helps retailers optimize their strategies. Founded in 2012 and based in Boston, Massachusetts, NewStore also has offices in New York and Germany. It was originally known as GoodsCloud Inc. before rebranding in 2015.

Catalant is a software company that offers a platform designed to connect global enterprises with business expertise on demand. The company supports over 30% of the Fortune 100 in accelerating their strategy execution through its innovative software solutions. Catalant's platform allows businesses to define their strategic objectives, break them down into actionable elements, and access both internal and external resources for execution. With a network of more than 65,000 experts and 1,000 firms, the platform facilitates collaboration and measures the value of work undertaken. Additionally, Catalant provides tools to manage this network efficiently. Headquartered in Boston, Massachusetts, the company serves clients worldwide, including private equity firms seeking to connect with qualified business professionals.

OM1, Inc. is a digital health company that specializes in developing a platform for healthcare organizations to measure and forecast patient outcomes. The platform is designed to assist hospitals, health systems, and other healthcare providers in meeting various patient reported and clinical outcomes requirements for value-based care programs. By leveraging advanced predictive and prescriptive analytics, OM1 aims to mitigate risks, lower costs, and enhance the understanding of treatment outcomes across the care continuum. The company's technology gathers and synthesizes clinical data to provide AI-driven insights, enabling healthcare organizations to analyze and utilize outcomes data effectively. Founded in 2014 and based in Boston, Massachusetts, OM1 was previously known as Better Outcomes Corporation.

Evolv Technology specializes in AI-based touchless security screening systems that prioritize safety while enhancing the visitor experience. The company's Mosaiq Platform integrates real-time video surveillance with advanced detection capabilities for firearms and explosives, facial recognition, and security analytics, all designed to minimize false alarms. Headquartered in Waltham, Massachusetts, Evolv is led by professionals with extensive backgrounds in security, including experience with the TSA, FBI, CIA, Secret Service, and Homeland Security. The firm offers its products through direct sales and a multi-year security-as-a-service subscription model, which not only provides ongoing value to clients but also fosters predictable revenue streams and opportunities for expansion. Evolv Technology aims to protect both public and private sectors by securing soft targets and vital assets.

Lola.com is an easy-to-use travel management tool that helps companies book, report, and save on business travel. Life becomes simpler with employee friendly business travel policies, fun travel tracking tools, and transparent spend reporting for business travel managers. For the business travelers, it enables easy flight and hotel booking, team destination sharing, loyalty points from the actual hotels and airlines, and 24/7 agent support. Its book on behalf feature lets executive assistants, easily book travel like a boss. Founded on 2015, Lola.com works for both employers and employees. It is headquartered in Boston, Massachusetts.

Enchi Corporation, based in Waltham, Massachusetts, specializes in the development of biological conversion systems that utilize engineered bacteria to convert non-food cellulosic biomass into fuels and chemicals. The company primarily focuses on the production of ethanol, which is recognized as a promising renewable fuel. Founded in 2005, Enchi Corporation operates as a subsidiary of Marathon Petroleum Corporation, contributing to advancements in biofuel technology and sustainable energy solutions.

Yottaa, Inc. is a cloud-based company that specializes in optimizing eCommerce experiences for brands and retailers. Founded in 2009 and based in Boston, Massachusetts, with an additional office in Beijing, Yottaa offers a range of solutions designed to enhance online consumer engagement. Its key products include InstantON, which accelerates page rendering to capture user attention, and AppSequencing, which prioritizes application elements for improved user interaction. The Rapid CTRL software enables online retailers to manage third-party applications effectively, while ImpactAnalytics provides insights on the return on investment from application optimization. Additionally, ContextIntelligence automates the contextual optimization of online and mobile applications. Yottaa serves a diverse clientele, including Internet retailers and Fortune 500 companies, helping them achieve faster, more secure, and efficient online interactions that drive conversions and enhance customer satisfaction. The company is trusted by over 1,500 leading sites, significantly boosting site speed and improving the overall shopper journey.

Catalant is a software company that offers a platform designed to connect global enterprises with business expertise on demand. The company supports over 30% of the Fortune 100 in accelerating their strategy execution through its innovative software solutions. Catalant's platform allows businesses to define their strategic objectives, break them down into actionable elements, and access both internal and external resources for execution. With a network of more than 65,000 experts and 1,000 firms, the platform facilitates collaboration and measures the value of work undertaken. Additionally, Catalant provides tools to manage this network efficiently. Headquartered in Boston, Massachusetts, the company serves clients worldwide, including private equity firms seeking to connect with qualified business professionals.

Circle is a financial technology firm that leverages blockchain technology and stablecoins to facilitate payments and e-commerce. Founded in 2013 by Jeremy Allaire and Sean Neville, Circle enhances the way users send and receive money through its platform, Circle Pay. The company offers a cryptocurrency investment product called Circle Invest, enabling users to buy and sell various crypto assets. Additionally, Circle provides over-the-counter trading services through Circle Trade, featuring one of the largest global liquidity pools for digital asset trading, with an average monthly volume of $2 billion. Backed by significant investments from notable firms, Circle operates from its headquarters in Boston and has branches in New York, San Francisco, Dublin, London, and Hong Kong.

Lola.com is an easy-to-use travel management tool that helps companies book, report, and save on business travel. Life becomes simpler with employee friendly business travel policies, fun travel tracking tools, and transparent spend reporting for business travel managers. For the business travelers, it enables easy flight and hotel booking, team destination sharing, loyalty points from the actual hotels and airlines, and 24/7 agent support. Its book on behalf feature lets executive assistants, easily book travel like a boss. Founded on 2015, Lola.com works for both employers and employees. It is headquartered in Boston, Massachusetts.

Kuvee is a direct to consumer wine service that also offers a wine bottle which keeps wine fresh for 30 days. Kuvee was launched by Vijay Manwani, Geoffrey Lansberry, and Mike Tomovich in 2014 and is based in Boston, Massachusetts.

BiOM (fromerly iWalk) is a Massachusetts based company whose sole product is the PowerFoot One. The Powerfoot One has two powerful microprocessors and six environmental sensors evaluate and adjust ankle position, stiffness, damping and power thousands of times a second. Control algorithms generate human-like force while traversing level ground, slopes and stairs, providing active amputees with near-normal gait and lower energy expenditure compared to state-of-the-art passive prosthetics.

Semantic Machines, Inc. is focused on developing advanced artificial intelligence technology to enhance human-computer interaction through conversational computing. The company specializes in creating conversational interfaces that enable computers to understand and engage in dialogue with users across various platforms, including speech and text. Their technology encompasses a Conversation Engine for fluid discourse, neural networks for semantic analysis and dialogue management, and speech recognition and synthesis capabilities. Additionally, Semantic Machines employs reinforcement learning to improve system performance over time by learning from user interactions. The company aims to transform customer experiences and reduce costs in sectors such as customer service and home automation. Based in Newton, Massachusetts, with additional offices in Berkeley and Boston, Semantic Machines operates as a subsidiary of Microsoft Corporation.

Fractyl Health, based in Lexington, Massachusetts, specializes in developing innovative medical device solutions for metabolic diseases, particularly type 2 diabetes and obesity. The company’s primary offering, Revita DMR, is a minimally invasive therapy that utilizes hydrothermal ablation to rejuvenate the duodenal lining, which can become compromised due to high-fat and high-sugar diets. By focusing on durable disease-modifying therapies rather than just symptomatic management, Fractyl Health aims to address the underlying causes of metabolic diseases, improving patient outcomes and reducing healthcare burdens. Founded in 2010 and originally named MedCatalyst, Inc., the company envisions a future where less invasive, device-based therapies provide effective solutions for large populations affected by metabolic disorders.

Outlearn Inc. is a Boston-based company that operates a cloud-based platform designed for creating, sharing, and delivering custom online learning for professional software developers. The platform allows individual developers and teams to assemble modular learning content from various sources into personalized learning paths. Outlearn also features a curated content catalog, enabling users to discover and publish original content while facilitating trackable learning experiences for organizations. Originally established as Hatchlearn Inc. in 2014, the company rebranded to Outlearn Inc. in February 2015. The goal of Outlearn is to simplify and enhance the process of online learning for developers, akin to the transformative impacts of GitHub, Wikipedia, and iTunes in their respective fields.

FlightCar, Inc. is a car rental service that operates an online platform connecting car owners with travelers in need of vehicles while at the airport. Founded in 2012 and based in San Francisco, California, FlightCar allows individuals who are parking their cars at airports to rent them out to other approved travelers, providing a cost-effective and convenient option for transportation. The company has expanded its services to multiple locations across the United States, including major cities such as Austin, Boston, Chicago, Los Angeles, and Seattle. By facilitating this peer-to-peer rental system, FlightCar aims to enhance the travel experience for both car owners and renters, promoting a collaborative community among travelers.

NewStore, Inc. is a technology company that offers an Omnichannel-as-a-Service platform designed for retailers to enhance their operations and customer engagement. The platform facilitates mobile commerce through an integrated cloud order management system and mobile point of sale, enabling seamless shopping experiences such as endless aisle access, mobile checkout, and real-time inventory management. NewStore allows brands to create a unified experience by connecting consumers, stores, and sales associates, thereby fostering innovation in retail. The company provides valuable insights into various aspects of retail operations, including store health and performance tracking, which helps retailers optimize their strategies. Founded in 2012 and based in Boston, Massachusetts, NewStore also has offices in New York and Germany. It was originally known as GoodsCloud Inc. before rebranding in 2015.

Superpedestrian, Inc. is a robotics company based in Cambridge, Massachusetts, that specializes in developing lightweight electric vehicles designed for eco-friendly transportation. The company’s flagship product, the Copenhagen Wheel, integrates advanced technology to enhance cycling safety and wellness, while also offering a platform for developers to create various applications. These applications range from navigation assistance to customization of the wheel's behavior. Superpedestrian sells its products through both retail channels and online platforms. Founded in 2012, the company aims to provide a comfortable and secure cycling experience by utilizing vehicle intelligence to monitor and address potential malfunctions proactively.

Circle is a financial technology firm that leverages blockchain technology and stablecoins to facilitate payments and e-commerce. Founded in 2013 by Jeremy Allaire and Sean Neville, Circle enhances the way users send and receive money through its platform, Circle Pay. The company offers a cryptocurrency investment product called Circle Invest, enabling users to buy and sell various crypto assets. Additionally, Circle provides over-the-counter trading services through Circle Trade, featuring one of the largest global liquidity pools for digital asset trading, with an average monthly volume of $2 billion. Backed by significant investments from notable firms, Circle operates from its headquarters in Boston and has branches in New York, San Francisco, Dublin, London, and Hong Kong.

Yottaa, Inc. is a cloud-based company that specializes in optimizing eCommerce experiences for brands and retailers. Founded in 2009 and based in Boston, Massachusetts, with an additional office in Beijing, Yottaa offers a range of solutions designed to enhance online consumer engagement. Its key products include InstantON, which accelerates page rendering to capture user attention, and AppSequencing, which prioritizes application elements for improved user interaction. The Rapid CTRL software enables online retailers to manage third-party applications effectively, while ImpactAnalytics provides insights on the return on investment from application optimization. Additionally, ContextIntelligence automates the contextual optimization of online and mobile applications. Yottaa serves a diverse clientele, including Internet retailers and Fortune 500 companies, helping them achieve faster, more secure, and efficient online interactions that drive conversions and enhance customer satisfaction. The company is trusted by over 1,500 leading sites, significantly boosting site speed and improving the overall shopper journey.

Outlearn Inc. is a Boston-based company that operates a cloud-based platform designed for creating, sharing, and delivering custom online learning for professional software developers. The platform allows individual developers and teams to assemble modular learning content from various sources into personalized learning paths. Outlearn also features a curated content catalog, enabling users to discover and publish original content while facilitating trackable learning experiences for organizations. Originally established as Hatchlearn Inc. in 2014, the company rebranded to Outlearn Inc. in February 2015. The goal of Outlearn is to simplify and enhance the process of online learning for developers, akin to the transformative impacts of GitHub, Wikipedia, and iTunes in their respective fields.

Visible Measures Corporation, established in 2005 and headquartered in Boston, Massachusetts, specializes in content advertising technology that assists brands in enhancing consumer engagement through video content. The company provides independent third-party measurement solutions for internet video publishers and advertisers, enabling the analysis of video performance data and the measurement of content consumption and viral distribution. Its data management platform, known as VisibleSuite, offers insights into audience interactions with video content, allowing advertisers to optimize their strategies and maximize their share of attention relative to media spending. Visible Measures operates as a subsidiary of AcuityAds US Inc. since March 2017.

FlightCar, Inc. is a car rental service that operates an online platform connecting car owners with travelers in need of vehicles while at the airport. Founded in 2012 and based in San Francisco, California, FlightCar allows individuals who are parking their cars at airports to rent them out to other approved travelers, providing a cost-effective and convenient option for transportation. The company has expanded its services to multiple locations across the United States, including major cities such as Austin, Boston, Chicago, Los Angeles, and Seattle. By facilitating this peer-to-peer rental system, FlightCar aims to enhance the travel experience for both car owners and renters, promoting a collaborative community among travelers.

Fractyl Health, based in Lexington, Massachusetts, specializes in developing innovative medical device solutions for metabolic diseases, particularly type 2 diabetes and obesity. The company’s primary offering, Revita DMR, is a minimally invasive therapy that utilizes hydrothermal ablation to rejuvenate the duodenal lining, which can become compromised due to high-fat and high-sugar diets. By focusing on durable disease-modifying therapies rather than just symptomatic management, Fractyl Health aims to address the underlying causes of metabolic diseases, improving patient outcomes and reducing healthcare burdens. Founded in 2010 and originally named MedCatalyst, Inc., the company envisions a future where less invasive, device-based therapies provide effective solutions for large populations affected by metabolic disorders.

Black Duck secures and manages open source software worldwide, eliminating open source security vulnerabilities and license compliance pain. With the rapid, widespread adoption of open-source software, Black Duck is a key component of Synopsys’ Software Integrity Platform, the most comprehensive solution for integrating security into the SDLC and software supply chain. Black Duck was established in 2002 and is based in Burlington, Massachusetts, United States.

Corvia Medical is a medical device company based in Andover, Massachusetts, established in 2009. The company specializes in developing innovative solutions for heart failure, particularly through its InterAtrial Shunt Device (IASD). This transcatheter device is designed to address diastolic heart failure, also known as heart failure with preserved ejection fraction. The IASD works by creating a small opening between the left and right atria, which helps to lower blood pressure in the left atrium and lungs. This reduction in pressure aims to alleviate symptoms and slow the progression of heart failure, allowing patients to maintain a healthier lifestyle and reduce their risk of severe heart-related complications.

Superpedestrian, Inc. is a robotics company based in Cambridge, Massachusetts, that specializes in developing lightweight electric vehicles designed for eco-friendly transportation. The company’s flagship product, the Copenhagen Wheel, integrates advanced technology to enhance cycling safety and wellness, while also offering a platform for developers to create various applications. These applications range from navigation assistance to customization of the wheel's behavior. Superpedestrian sells its products through both retail channels and online platforms. Founded in 2012, the company aims to provide a comfortable and secure cycling experience by utilizing vehicle intelligence to monitor and address potential malfunctions proactively.

Circle is a financial technology firm that leverages blockchain technology and stablecoins to facilitate payments and e-commerce. Founded in 2013 by Jeremy Allaire and Sean Neville, Circle enhances the way users send and receive money through its platform, Circle Pay. The company offers a cryptocurrency investment product called Circle Invest, enabling users to buy and sell various crypto assets. Additionally, Circle provides over-the-counter trading services through Circle Trade, featuring one of the largest global liquidity pools for digital asset trading, with an average monthly volume of $2 billion. Backed by significant investments from notable firms, Circle operates from its headquarters in Boston and has branches in New York, San Francisco, Dublin, London, and Hong Kong.

Kensho Technologies, Inc. specializes in analytics, artificial intelligence, machine learning, and data visualization systems tailored for global banks and investment institutions. Founded in 2012 and headquartered in Cambridge, Massachusetts, with additional offices in New York, Virginia, and California, Kensho develops financial analytics software that enables scalable analytics solutions for commercial entities. Its offerings include Kensho Applied Mind, an AI software that enhances decision-making by addressing complex financial inquiries in natural language. The company also operates a national security division known as Koto. As of April 2018, Kensho operates as a subsidiary of S&P Global Inc.

ownCloud is the company behind the ownCloud project – the most downloaded open source project for data and file sync, share and view. ownCloud enables businesses to host their own, on premises or remote, cloud storage while maintaining regulatory and compliance needs. Located in Boston, Massachusetts with an international office in Germany we offer your cloud with your data – your way!

CoachUp, Inc. is a private coaching company that operates an online platform designed to connect athletes with private coaches across the United States. Founded in 2011 and headquartered in Newton Upper Falls, Massachusetts, the website allows users to search for coaches by location and sport, including basketball, soccer, fitness, and yoga. Athletes can read coach profiles, send messages, and book sessions, while coaches benefit from resources that help them manage and grow their coaching practices. The platform provides various services for coaches, including liability insurance, certification courses, payment processing, and marketing support. By facilitating this connection, CoachUp aims to enhance athletic performance and help individuals achieve their personal fitness goals.

Paydiant, Inc. offers a cloud-based white label mobile wallet platform that allows merchants, banks, and partners to integrate mobile payments, loyalty programs, offers, and ATM cash access into their own branded mobile applications. Founded in 2010 and located in Auburndale, Massachusetts, the company enables its clients to deploy secure mobile wallet solutions tailored to their brand without the need for new intermediaries. Paydiant's patented technology supports the development of customized mobile wallet experiences, facilitating a seamless connection between businesses and their customers. As of April 2015, Paydiant operates as a subsidiary of PayPal Holdings.

Datto provides backup, recovery, and business continuity solutions to managed service providers worldwide. Its products include ALTO, a business continuity solution designed specifically for small businesses, SIRIS, a family of enterprise business continuity solutions that are available in physical and virtual platforms, Datto NAS, a cloud storage solution, and Backupify, a cloud-to-cloud backup and recovery solution for Software-as-a-Service (SaaS) applications that include Google Apps and Salesforce. Datto offers its solutions for data on-premises in a physical or virtual server, or in the cloud via SaaS applications. It serves small businesses to enterprises in the United States, Canada, and the United Kingdom. Austin McChord founded Datto in 2007. Its headquarters in Norwalk in Connecticut, with additional offices in Germany and the Netherlands. Datto has operations in Australia and New Zealand. Datto operates as a subsidiary of Autotask Corporation as of December 11, 2017.

Evolv Technology specializes in AI-based touchless security screening systems that prioritize safety while enhancing the visitor experience. The company's Mosaiq Platform integrates real-time video surveillance with advanced detection capabilities for firearms and explosives, facial recognition, and security analytics, all designed to minimize false alarms. Headquartered in Waltham, Massachusetts, Evolv is led by professionals with extensive backgrounds in security, including experience with the TSA, FBI, CIA, Secret Service, and Homeland Security. The firm offers its products through direct sales and a multi-year security-as-a-service subscription model, which not only provides ongoing value to clients but also fosters predictable revenue streams and opportunities for expansion. Evolv Technology aims to protect both public and private sectors by securing soft targets and vital assets.

Yottaa, Inc. is a cloud-based company that specializes in optimizing eCommerce experiences for brands and retailers. Founded in 2009 and based in Boston, Massachusetts, with an additional office in Beijing, Yottaa offers a range of solutions designed to enhance online consumer engagement. Its key products include InstantON, which accelerates page rendering to capture user attention, and AppSequencing, which prioritizes application elements for improved user interaction. The Rapid CTRL software enables online retailers to manage third-party applications effectively, while ImpactAnalytics provides insights on the return on investment from application optimization. Additionally, ContextIntelligence automates the contextual optimization of online and mobile applications. Yottaa serves a diverse clientele, including Internet retailers and Fortune 500 companies, helping them achieve faster, more secure, and efficient online interactions that drive conversions and enhance customer satisfaction. The company is trusted by over 1,500 leading sites, significantly boosting site speed and improving the overall shopper journey.

Datalogix is a prominent company specializing in connecting digital media with offline purchasing data, enabling marketers to enhance the effectiveness and measurability of their advertising efforts. The company serves more than half of the top 100 consumer marketers and manages the DLX Platform, which encompasses over $1 trillion in consumer spending and supports campaigns for a significant majority of online media companies. Datalogix's DLX ROI is becoming a standard for measuring the impact of digital media on offline sales. Additionally, the company provides predictive analytics for direct mail and integrated media solutions through the DLX Net. Its expertise covers various consumer sectors, including retail, consumer packaged goods, automotive, telecommunications, travel, and financial services. Headquartered in Colorado, Datalogix has established offices in key cities such as New York City, San Francisco, Boston, Chicago, Detroit, and London.

FlightCar, Inc. is a car rental service that operates an online platform connecting car owners with travelers in need of vehicles while at the airport. Founded in 2012 and based in San Francisco, California, FlightCar allows individuals who are parking their cars at airports to rent them out to other approved travelers, providing a cost-effective and convenient option for transportation. The company has expanded its services to multiple locations across the United States, including major cities such as Austin, Boston, Chicago, Los Angeles, and Seattle. By facilitating this peer-to-peer rental system, FlightCar aims to enhance the travel experience for both car owners and renters, promoting a collaborative community among travelers.

Corvia Medical is a medical device company based in Andover, Massachusetts, established in 2009. The company specializes in developing innovative solutions for heart failure, particularly through its InterAtrial Shunt Device (IASD). This transcatheter device is designed to address diastolic heart failure, also known as heart failure with preserved ejection fraction. The IASD works by creating a small opening between the left and right atria, which helps to lower blood pressure in the left atrium and lungs. This reduction in pressure aims to alleviate symptoms and slow the progression of heart failure, allowing patients to maintain a healthier lifestyle and reduce their risk of severe heart-related complications.

DataGravity, Inc. is a software company that specializes in data management, focusing on enhancing data visibility, security, and availability for IT professionals. Founded in 2012 and headquartered in Nashua, New Hampshire, DataGravity offers solutions that help identify and protect sensitive data from exposure, loss, and regulatory noncompliance. Its products include DataGravity for Availability, which integrates with Veeam availability suite backups to monitor and analyze data usage, and DataGravity for Virtualization, which provides file and user activity tracking. The platform is designed to assist IT managers and administrators in extracting valuable insights from stored data, ultimately improving data security and management practices. As of July 2017, DataGravity operates as a subsidiary of HyTrust, Inc.

ownCloud is the company behind the ownCloud project – the most downloaded open source project for data and file sync, share and view. ownCloud enables businesses to host their own, on premises or remote, cloud storage while maintaining regulatory and compliance needs. Located in Boston, Massachusetts with an international office in Germany we offer your cloud with your data – your way!

CoachUp, Inc. is a private coaching company that operates an online platform designed to connect athletes with private coaches across the United States. Founded in 2011 and headquartered in Newton Upper Falls, Massachusetts, the website allows users to search for coaches by location and sport, including basketball, soccer, fitness, and yoga. Athletes can read coach profiles, send messages, and book sessions, while coaches benefit from resources that help them manage and grow their coaching practices. The platform provides various services for coaches, including liability insurance, certification courses, payment processing, and marketing support. By facilitating this connection, CoachUp aims to enhance athletic performance and help individuals achieve their personal fitness goals.

SynapDx is a laboratory testing service provider focused on the early detection of autism spectrum disorders (ASDs) in children. Founded by Stanley Lapidus, the company aims to assist physicians in evaluating developmental disorders through innovative blood-based diagnostic tests and equipment. By collaborating with experts in ASD and gene expression from prominent institutions, SynapDx seeks to enhance the capability of healthcare providers to identify early symptoms of autism. The company is headquartered in Lexington, Massachusetts, and has secured funding from notable investors, including North Bridge Venture Partners, Bain Capital Ventures, and General Catalyst Partners.

Ramp is a company that specializes in providing modern solutions for financial operations and enterprise content delivery. Its financial platform includes tools for corporate card management, expense tracking, bill payments, and seamless accounting integrations, aimed at helping organizations optimize their financial tasks and reduce costs. Additionally, Ramp offers advanced video management and delivery software, enabling companies to enhance video content discovery, user engagement, and secure delivery. Its products, such as VideoVerge and AltitudeCDN, leverage innovative technologies like speech-to-text and natural language processing to create rich metadata for video assets, allowing them to be effectively integrated into popular content management systems. Ramp serves a diverse clientele, including prominent media companies and organizations across various industries such as healthcare, finance, and technology. Founded in 1948 and based in Boston, Massachusetts, Ramp operates as a subsidiary of Raytheon BBN Technologies Corporation.

BiOM (fromerly iWalk) is a Massachusetts based company whose sole product is the PowerFoot One. The Powerfoot One has two powerful microprocessors and six environmental sensors evaluate and adjust ankle position, stiffness, damping and power thousands of times a second. Control algorithms generate human-like force while traversing level ground, slopes and stairs, providing active amputees with near-normal gait and lower energy expenditure compared to state-of-the-art passive prosthetics.

Visible Measures Corporation, established in 2005 and headquartered in Boston, Massachusetts, specializes in content advertising technology that assists brands in enhancing consumer engagement through video content. The company provides independent third-party measurement solutions for internet video publishers and advertisers, enabling the analysis of video performance data and the measurement of content consumption and viral distribution. Its data management platform, known as VisibleSuite, offers insights into audience interactions with video content, allowing advertisers to optimize their strategies and maximize their share of attention relative to media spending. Visible Measures operates as a subsidiary of AcuityAds US Inc. since March 2017.

Paydiant, Inc. offers a cloud-based white label mobile wallet platform that allows merchants, banks, and partners to integrate mobile payments, loyalty programs, offers, and ATM cash access into their own branded mobile applications. Founded in 2010 and located in Auburndale, Massachusetts, the company enables its clients to deploy secure mobile wallet solutions tailored to their brand without the need for new intermediaries. Paydiant's patented technology supports the development of customized mobile wallet experiences, facilitating a seamless connection between businesses and their customers. As of April 2015, Paydiant operates as a subsidiary of PayPal Holdings.

Shareaholic, Inc. offers a content amplification platform that enhances the way marketers, publishers, and website owners present and share relevant content. Established in 2008 and based in Boston, Massachusetts, the platform helps increase website traffic, engagement, and time spent on site by highlighting pertinent content. It allows users to share various activities, such as articles and purchases, across multiple social media channels including Facebook, Twitter, and LinkedIn. Additionally, Shareaholic provides actionable metrics that offer insights into content performance and audience engagement. With its tools, the company supports over 300,000 websites in promoting their content and fostering customer loyalty, thereby driving online success for businesses globally.

DataGravity, Inc. is a software company that specializes in data management, focusing on enhancing data visibility, security, and availability for IT professionals. Founded in 2012 and headquartered in Nashua, New Hampshire, DataGravity offers solutions that help identify and protect sensitive data from exposure, loss, and regulatory noncompliance. Its products include DataGravity for Availability, which integrates with Veeam availability suite backups to monitor and analyze data usage, and DataGravity for Virtualization, which provides file and user activity tracking. The platform is designed to assist IT managers and administrators in extracting valuable insights from stored data, ultimately improving data security and management practices. As of July 2017, DataGravity operates as a subsidiary of HyTrust, Inc.

Yottaa, Inc. is a cloud-based company that specializes in optimizing eCommerce experiences for brands and retailers. Founded in 2009 and based in Boston, Massachusetts, with an additional office in Beijing, Yottaa offers a range of solutions designed to enhance online consumer engagement. Its key products include InstantON, which accelerates page rendering to capture user attention, and AppSequencing, which prioritizes application elements for improved user interaction. The Rapid CTRL software enables online retailers to manage third-party applications effectively, while ImpactAnalytics provides insights on the return on investment from application optimization. Additionally, ContextIntelligence automates the contextual optimization of online and mobile applications. Yottaa serves a diverse clientele, including Internet retailers and Fortune 500 companies, helping them achieve faster, more secure, and efficient online interactions that drive conversions and enhance customer satisfaction. The company is trusted by over 1,500 leading sites, significantly boosting site speed and improving the overall shopper journey.

OvaScience, Inc. was a fertility company focused on developing innovative treatments for women facing infertility challenges. The company was founded in 2011 and was headquartered in Waltham, Massachusetts. OvaScience specialized in proprietary technology derived from the discovery of egg precursor (EggPC) cells, which allowed for the enhancement of egg quality and improved outcomes in in vitro fertilization (IVF). Their treatment options included OvaPrime, which aimed to restore a woman's egg production using her own EggPC cells, OvaTure, designed to mature these cells into fertilizable eggs outside the body, and AUGMENT, which utilized mitochondria from EggPC cells to enhance fertilization and pregnancy rates. The company also explored OvaXon for preventing inherited diseases. OvaScience was co-founded by a team of experts from Harvard Medical School and was backed by prominent life science investors. In December 2018, OvaScience was acquired by Millendo Therapeutics in a reverse merger.

Shareaholic, Inc. offers a content amplification platform that enhances the way marketers, publishers, and website owners present and share relevant content. Established in 2008 and based in Boston, Massachusetts, the platform helps increase website traffic, engagement, and time spent on site by highlighting pertinent content. It allows users to share various activities, such as articles and purchases, across multiple social media channels including Facebook, Twitter, and LinkedIn. Additionally, Shareaholic provides actionable metrics that offer insights into content performance and audience engagement. With its tools, the company supports over 300,000 websites in promoting their content and fostering customer loyalty, thereby driving online success for businesses globally.

Black Duck secures and manages open source software worldwide, eliminating open source security vulnerabilities and license compliance pain. With the rapid, widespread adoption of open-source software, Black Duck is a key component of Synopsys’ Software Integrity Platform, the most comprehensive solution for integrating security into the SDLC and software supply chain. Black Duck was established in 2002 and is based in Burlington, Massachusetts, United States.