Ripcord
Venture Round in 2024
Ripcord, Inc. is a robotic digitization company that specializes in automating the management of paper records. Founded in 2014 and headquartered in Los Angeles, California, Ripcord develops a platform that utilizes advanced technologies, including artificial intelligence, machine learning, and vision-guided robotics, to create digital twins of physical documents. Its flagship solution, Canopy, captures, enriches, and organizes critical content, allowing enterprises to enhance their business processes with improved speed, quality, and accuracy. Formerly known as Ripcord Digital, Inc., the company rebranded in June 2017 to reflect its focus on innovative digitization solutions.
Tome Biosciences
Series A in 2023
Tome Biosciences is a biotechnology company specializing in programmable gene insertion technology. Utilizing CRISPR, the company develops methods to insert genetic sequences of any size at various locations within any genome. This innovative approach aims to enhance the ability to detect and eliminate deoxyribonucleic acid from similar bacteriophages during infections. By advancing cell and genome engineering, Tome Biosciences seeks to provide effective therapeutic solutions for patients, paving the way for significant advancements in genetic medicine.
MicroChannel Services
Acquisition in 2023
MicroChannel Services is a multi-award-winning provider of business solutions and technology, established in 1995. The company serves mid-sized businesses, corporate divisions, and government agencies, assisting them in leveraging technology for improved commercial success. MicroChannel offers a range of services including customer relationship management, marketing technology, enterprise resource planning, warehouse management, and retail management. In addition, the company provides managed IT services and comprehensive business consultancy, enabling clients to enhance productivity, drive growth, and improve competitiveness in their respective markets. With a focus on delivering end-to-end operational and back-office systems, MicroChannel has successfully supported hundreds of clients in achieving their business objectives.
Inspirata
Acquisition in 2022
Inspirata, Inc. is an oncology informatics company dedicated to enhancing the cancer care experience for patients and clinicians. The firm provides innovative software solutions that utilize advanced artificial intelligence and natural language processing to streamline clinical trials and cancer registry operations. With over two decades of collaboration with the National Cancer Institute, Inspirata's proprietary AI and NLP engine powers key products such as Trial Navigator, which automates clinical trial matching, and E-Path Plus, a leading solution for cancer registry reporting and data abstraction. These tools are used by numerous healthcare institutions worldwide, aiming to improve patient outcomes and support healthcare professionals in their fight against cancer.
24M Technologies specializes in the development of innovative energy storage systems aimed at enhancing the operational reliability and efficiency of electric power systems for both grid and transportation applications. The company is known for its advanced lithium-ion batteries, which feature binder-free semisolid electrodes and unit cells. These designs not only improve battery performance but also streamline the recycling process by eliminating the need for traditional hydro or pyrometallurgical methods. Additionally, 24M facilitates the direct reuse of active materials within its manufacturing process, supporting sustainable end-of-life recycling practices. Through these innovations, 24M aims to provide clients with improved economic outcomes while contributing to more efficient energy storage solutions.
Cuorips
Venture Round in 2021
Cuorips Inc. is a medical care company based in Chuo, Japan, with an additional office in Osaka. Founded in 2017, it focuses on the research, development, and commercialization of iPS cell-derived cardiomyocyte sheets and various cell therapeutic products. The company offers manufacturing and sales of cellular and tissue-based products, along with contract development and manufacturing services. Cuorips aims to advance medical treatments through innovation in cell processing and therapeutic applications.
Rege Nephro
Series A in 2020
Rege Nephro Co., Ltd. is a biotechnology company based in Kyoto, Japan, founded in 2019. It specializes in the research and development, production, and marketing of therapeutics for renal diseases, utilizing nephron progenitor cells and induced pluripotent stem cell (iPSC) technology from the Center for iPS Cell Research and Application at Kyoto University. The company focuses on developing innovative treatments and cell therapies for kidney, liver, and pancreas diseases, aiming to reduce the reliance on dialysis for patients with renal failure. Additionally, Rege Nephro produces kidney organoids that facilitate nephrotoxicity screening for drug discovery, enhancing applied research in the field of nephrology.
Nanox Imaging
Series B in 2020
Nanox Imaging is a Gibraltar-based company founded in 2011 that specializes in advanced imaging technology for medical, security, and telecommunications applications. The company is pioneering next-generation X-ray emitters utilizing innovative nanotechnology to modernize X-ray imaging, enabling the development of novel 3D imaging systems with superior performance. Central to Nanox's offerings is the Nanox System, which provides a preventative healthcare service known as Medical Screening As A Service (MSaaS). The company has leveraged over two decades of research and development, investing more than $1 billion to create proprietary cold cathode technology that enhances X-ray imaging capabilities. This technology features a chip composed of nano-scale structures, designed through unique nanofabrication techniques, which supports various medical imaging applications and is complemented by additional technologies to maximize its practical benefits in real-world scenarios.
Lunit Inc. is a medical AI software company based in Seoul, South Korea, specializing in advanced algorithms for medical image analysis and general object detection. The company focuses on developing solutions that aid physicians in making objective diagnoses through machine learning technology. Lunit's expertise encompasses various medical imaging fields, including digital chest X-ray, digital mammography, digital pathology, and fundus photography. The company's products include Lunit INSIGHT CXR for chest X-rays, Lunit INSIGHT MMG for mammography, and Lunit SCOPE, which provides AI-powered biomarkers for immuno-oncology. Lunit aims to enhance clinical decision-making by leveraging data-driven imaging biomarker technology, ultimately improving the accuracy and efficiency of cancer care. The effectiveness of Lunit's deep learning technology has been validated through its recognition in major image recognition competitions, showcasing its capacity to process complex medical imaging data.
Fuji Xerox
Acquisition in 2019
Fuji Xerox New Zealand is part of a global enterprise group that specializes in business and document management services. The company offers a comprehensive suite of technologies and solutions, including digital printing, document management, and business process outsourcing. By helping businesses reduce printing costs, streamline processes, and automate tasks, Fuji Xerox New Zealand aims to enhance operational efficiency and drive cost savings. The organization is committed to fostering long-term relationships with its clients and communities, and it actively supports various environmental, educational, and sporting initiatives. Through its scalable and cost-effective solutions, Fuji Xerox New Zealand seeks to empower local businesses to grow and transform.
Century Therapeutics
Series A in 2019
Century Therapeutics, Inc. is a biotechnology company focused on developing innovative cell therapies derived from induced pluripotent stem cells (iPSCs) to treat hematologic and solid malignancies. Founded in 2018 and headquartered in Philadelphia, Pennsylvania, the company utilizes a specialized platform that integrates gene editing and protein engineering to create allogeneic therapies. This platform allows for the generation of master cell banks of modified immune effector cells, specifically engineered to optimize performance and reduce the risk of rejection by the host immune system. By employing advanced technologies such as CRISPR-mediated gene editing and proprietary chimeric antigen receptors, Century Therapeutics aims to address significant unmet medical needs in cancer and other diseases.
PuREC is a biotechnology company focused on developing advanced culture technologies to enhance treatment efficacy. The company specializes in rapidly evolving cell therapies and mesenchymal stem cell therapies. Its innovative approach addresses specific medical conditions, including hypophosphatasia, a rare bone-formation deficiency affecting newborns, and spinal canal stenosis, which is often caused by disc herniation. By leveraging its technological advancements, PuREC aims to empower healthcare providers in their efforts to combat various diseases and transform the landscape of transplantation medicine.
Junten Bio
Corporate Round in 2019
Junten Bio is a biotechnology company focused on the research and development of cell medicines utilizing regenerative medicine technology. The company aims to enhance medical care through innovative products that address the challenges of immune rejection in organ transplantation. By investigating the mechanisms behind immune rejection, Junten Bio works on developing cell therapies that can minimize the side effects associated with immunosuppressive treatments, ultimately helping patients achieve a better quality of life while reducing overall medical expenses.
LPixel Inc. is a Tokyo-based company that specializes in life science image analysis software solutions. Founded in 2014 as a spin-out from the University of Tokyo, LPixel develops a range of products, including plugins for ImageJ that assist life science researchers, as well as LP-exam, a tool for detecting image manipulations and plagiarism. The company’s flagship offering, IMACEL, leverages cloud computing and artificial intelligence to provide advanced image analysis capabilities, enabling morphological analysis, total cell count calculations, and automatic image classification. This innovative platform supports researchers in identifying anomalies in medical images and aims to enhance research efficiency. In addition to its software solutions, LPixel offers educational programs tailored for life science researchers and students, further contributing to the advancement of the field.
Suono Bio
Corporate Round in 2018
Suono Bio, Inc. is a biotechnology company based in Medford, Massachusetts, that focuses on designing and developing innovative therapeutic products with a unique delivery technology. Established in 2016, the company specializes in enabling ultra-rapid, localized delivery of small molecules, biologics, nucleic acids, and gene therapies directly to the gastrointestinal tract without the need for encapsulation. Suono Bio aims to transform the treatment landscape for difficult-to-treat diseases, particularly those mediated by inflammatory processes, by facilitating effective therapy delivery that enhances patient recovery from gastrointestinal conditions.
Perseus Proteomics
Venture Round in 2018
Perseus Proteomics Inc. is a biotechnology company based in Tokyo, Japan, focused on drug discovery. Established in 2001, it specializes in antibody discovery, engineering, and research support activities. The company engages in target discovery and functional protein expression, offering services such as mouse hybridoma sequencing, recombinant protein production, and contract research for antibodies. Additionally, Perseus Proteomics develops, manufactures, and supplies a range of antibody products. By leveraging advanced antibody technology, the company aims to create innovative medicines that address the needs of patients worldwide seeking improved medical care.
IS Japan
Acquisition in 2018
IS Japan, founded in 1989, manufactures in vitro fertilization products, products for cell culture, and products for research on regenerative medicine and cell therapy, and distributes Irvine Scientific's products in and outside Japan.
Xerox is a global technology company specializing in document management and printing solutions. It offers a wide range of products and services, including printing systems, digital presses, multifunction devices, and related software. Xerox also provides consulting, outsourcing, and managed print services to businesses, helping them optimize their document workflows and IT infrastructure. The company operates primarily in the U.S. (60% of revenue) and internationally (40%).
EdiGENE Japan
Series A in 2017
EdiGENE Japan, now known as Modalis Therapeutics Corporation, is an emerging biotechnology company based in Tokyo, Japan. Founded in 2016, it specializes in the research and development of innovative therapeutics aimed at addressing serious genetic disorders. The company utilizes its proprietary CRISPR-GNDM technology, which allows for locus-specific modulation of gene expression and histone modification without the necessity for double-stranded DNA cleavage or traditional gene editing techniques. Modalis Therapeutics has established a solid intellectual property foundation, including licenses from the University of Tokyo, to support its focus on developing treatments for orphan genetic diseases and other unmet medical needs.
EdiGene Inc. is a biotechnology company specializing in the development of genome editing technologies for therapeutic applications in cancer and various genetic diseases. Founded in 2015 and headquartered in Beijing, China, with additional offices in Guangzhou and Cambridge, Massachusetts, EdiGene focuses on both ex vivo and in vivo gene-editing therapies. The company has established proprietary platforms for editing hematopoietic stem cells and T cells, as well as an RNA base editing approach for in vivo applications. EdiGene's innovative methods enable targeted modifications of genetic information in human cells and facilitate high-throughput drug discovery through advanced screening techniques. By translating these technologies into novel therapeutics, EdiGene aims to improve the safety and efficacy of gene therapy, ultimately benefiting patients, the pharmaceutical industry, and the scientific research community.
Cyfuse Biomedical
Venture Round in 2017
Cyfuse Biomedical K.K., established in 2010 with headquarters in Tokyo, Japan, specializes in the research, development, and commercialization of tissue fabrication systems and cell-based products on a global scale. The company's core business involves creating and selling advanced 3D BioFabrication systems along with associated consumables. These systems automate the assembly of cells into complex 3D structures, enabling researchers to explore various cell delivery strategies. Cyfuse Biomedical also develops and licenses 3D tissue products for therapeutic applications and drug development purposes, spanning blood vessel grafts for hemodialysis patients or coronary bypasses, cardiac grafts for drug screening or myocardial infarction therapy, cartilage grafts for reconstructive surgeries, and hepatocyte grafts for drug metabolism studies or hemophilia treatment. Additionally, the company offers contract manufacturing services for 3D tissue products tailored to research needs. Its primary clientele comprises research institutions and universities worldwide.
Tokiwa Bio
Venture Round in 2017
Tokiwa Bio Inc. is a Japanese company based in Tsukuba that specializes in the development and manufacturing of drugs for regenerative medicine, particularly focusing on gene therapy. Founded in 2014, the company utilizes artificially synthesized vectors to introduce multiple genes into the cytoplasm of cells without causing damage to the existing genetic material. This innovative approach facilitates the creation of gene therapy drugs aimed at treating rare diseases, including hemophilia and ischemia. In addition to its gene therapy efforts, Tokiwa Bio also produces biopharmaceuticals, antibody drugs, and research reagents, positioning itself as a key player in the biopharmaceutical industry.
Bonac
Venture Round in 2017
BONAC Corporation is a biotechnology company focused on the research, development, and commercialization of nucleic acid pharmaceutical products utilizing advanced nucleic acid platform technology. Established in 2010 and headquartered in Kurume, Japan, with a branch office in Tokyo, BONAC specializes in manufacturing nucleic acid drug substances and providing comprehensive drug development support. The company aims to enable drug and cosmetic manufacturers to access innovative drug substances that address unmet medical needs through its expertise in nucleic acid medicines and RNA technology.
RegCell
Venture Round in 2017
RegCell is a biotechnology company focused on developing innovative therapeutic technologies to address autoimmune diseases and cancer. The company specializes in creating advanced cell therapies that work by controlling and augmenting the immune system. RegCell's approach involves returning regulatory T cells and activating them in vitro, allowing for effective treatment options for patients facing these challenging health conditions. By targeting unmet medical needs, RegCell aims to improve patient outcomes and provide new hope for those suffering from autoimmune disorders and cancer.
Cynata Therapeutics Limited is an Australian company focused on developing and commercializing its proprietary Cymerus™ mesenchymal stem cell technology for therapeutic applications. The company’s lead product candidate, CYP-001, has completed Phase I clinical trials aimed at treating graft versus host disease. In addition to this, Cynata is exploring treatments for various conditions such as asthma, heart attack, diabetic wounds, coronary artery disease, and acute respiratory distress syndrome, among others, which are currently in preclinical stages. The Cymerus technology utilizes induced pluripotent stem cells (iPSCs) derived from adult donors, enabling the efficient and scalable production of mesenchymal stem cells. This innovative approach addresses existing limitations in stem cell manufacturing, allowing for virtually limitless quantities of therapeutic cells without the need for continuous donor sourcing. Cynata collaborates with several prestigious institutions, including Monash University and Massachusetts General Hospital, to advance its research and development efforts. Founded in 2011 and based in Carlton, Australia, Cynata is positioned to significantly contribute to the field of regenerative medicine.
Ultra Pure Solutions
Acquisition in 2015
Ultra Pure Solutions, Inc. is one of the largest manufacturers of high purity chemicals in North America.
TeraMedica
Acquisition in 2015
FUJIFILM TeraMedica, Inc., based in Milwaukee, WI, is a prominent healthcare informatics company specializing in vendor-neutral, enterprise-wide solutions for medical image management. Founded in 2001, the company gained recognition for deploying the first cross-departmental, patient-centric clinical image archive at Mayo Clinic in 2003. TeraMedica's software has since been implemented in over 600 healthcare facilities across six continents, demonstrating its adaptability and commitment to meeting customer needs. The company's focus on providing comprehensive clinical content management services positions it as a leader in the healthcare informatics sector, dedicated to enhancing the efficiency and accessibility of medical imaging for healthcare enterprises.
Cellular Dynamics International
Acquisition in 2015
Cellular Dynamics International Inc., (CDI) is a developer and manufacturer of fully functioning cells in industrial quantities to precise specifications. CDI's proprietary products include true human cells in multiple cell types (iCell products), human induced pluripotent stem cells (iPSCs) and custom iPSCs and iCell products (MyCell Products). CDI's products provide standardized, easy-to-use, cost-effective access to the human cell, the smallest fully functioning operating unit of human biology. Customers use our products, among other purposes, for drug discovery and screening, to test the safety and efficacy of their small molecule and biological drug candidates, for stem cell banking, and in the research and development of cellular therapeutics.
Sonosite
Acquisition in 2011
SonoSite, Inc. is a leading provider of hand-carried ultrasound systems, specializing in the portable ultrasound market. The company has revolutionized diagnostic imaging by developing systems that deliver high-quality performance traditionally found in larger, expensive machines but in a compact, laptop-sized format. This innovation allows for enhanced efficiency in existing clinical settings and introduces new point-of-care applications in areas where ultrasound was previously impractical due to size or cost. SonoSite's products cater to various medical fields, including radiology, cardiology, obstetrics and gynecology, emergency medicine, and critical care. With over 40,000 systems sold since its inception in 1999, the company is recognized for its exceptional imaging performance, user-friendly design, and durability, ultimately contributing to safer and more affordable healthcare delivery in hospitals and clinical environments.
Perseus Proteomics
Acquisition in 2009
Perseus Proteomics Inc. is a biotechnology company based in Tokyo, Japan, focused on drug discovery. Established in 2001, it specializes in antibody discovery, engineering, and research support activities. The company engages in target discovery and functional protein expression, offering services such as mouse hybridoma sequencing, recombinant protein production, and contract research for antibodies. Additionally, Perseus Proteomics develops, manufactures, and supplies a range of antibody products. By leveraging advanced antibody technology, the company aims to create innovative medicines that address the needs of patients worldwide seeking improved medical care.
Perseus Proteomics
Venture Round in 2009
Perseus Proteomics Inc. is a biotechnology company based in Tokyo, Japan, focused on drug discovery. Established in 2001, it specializes in antibody discovery, engineering, and research support activities. The company engages in target discovery and functional protein expression, offering services such as mouse hybridoma sequencing, recombinant protein production, and contract research for antibodies. Additionally, Perseus Proteomics develops, manufactures, and supplies a range of antibody products. By leveraging advanced antibody technology, the company aims to create innovative medicines that address the needs of patients worldwide seeking improved medical care.
Dimatix
Acquisition in 2006
Dimatix is a world leader in the research, development, manufacture and sale of printheads used in industrial inkjet printers, which are increasingly being used in such fields as outdoor advertising and packaging materials. As such, the company supplies printheads and provides after-sales service to printer manufacturers and various other users. Using MEMS1, Dimatix has developed advanced piezoelectric printheads2 that feature superior quality and excellent durability.
Perseus Proteomics
Corporate Round in 2006
Perseus Proteomics Inc. is a biotechnology company based in Tokyo, Japan, focused on drug discovery. Established in 2001, it specializes in antibody discovery, engineering, and research support activities. The company engages in target discovery and functional protein expression, offering services such as mouse hybridoma sequencing, recombinant protein production, and contract research for antibodies. Additionally, Perseus Proteomics develops, manufactures, and supplies a range of antibody products. By leveraging advanced antibody technology, the company aims to create innovative medicines that address the needs of patients worldwide seeking improved medical care.
Sericol Group
Acquisition in 2005
Sericol is a global corporation engaged in the development, manufacturing and sale of inks for screen and package printing as well as industrial inkjet inks and materials. With inks for screen printing and wide format digital UV inkjet inks, the company maintains a leading market share position worldwide.