Fountain Healthcare Partners

Mainstay Medical is a global medical device company based in Dublin, Ireland, with additional operations in the United States and Australia. The company specializes in developing innovative therapies for individuals suffering from chronic low back pain, a condition that affects a significant underserved population. Mainstay Medical has created an FDA-approved restorative treatment designed to enhance muscle control and improve functionality in the lumbar spine. This therapy aims to help patients regain mobility and enhance their overall quality of life. By collaborating with scientists and clinical experts, Mainstay Medical is committed to advancing solutions for those affected by debilitating back pain.

Vivasure Medical Limited is a medical device company based in Galway, Ireland, that specializes in the research, development, and manufacture of arterial and venous closure devices utilizing its patented PerQseal technology. The company focuses on creating polymer implants and delivery systems aimed at minimally invasive vessel closures, primarily in cardiology, interventional radiology, and vascular surgery. Its flagship product is an absorbable patch-based large-bore percutaneous closure device, designed to effectively close large arteriotomies resulting from transcatheter procedures, including transcatheter aortic valve replacement and endovascular aneurysm repair. Founded in 2008, Vivasure Medical is committed to advancing techniques that enhance patient outcomes in vascular access procedures.

Mainstay Medical is a global medical device company based in Dublin, Ireland, with additional operations in the United States and Australia. The company specializes in developing innovative therapies for individuals suffering from chronic low back pain, a condition that affects a significant underserved population. Mainstay Medical has created an FDA-approved restorative treatment designed to enhance muscle control and improve functionality in the lumbar spine. This therapy aims to help patients regain mobility and enhance their overall quality of life. By collaborating with scientists and clinical experts, Mainstay Medical is committed to advancing solutions for those affected by debilitating back pain.

Neurent Medical Limited is a medical device company based in Galway, Ireland, founded in 2015 by Brian Shields and David Townley. The company specializes in developing non-surgical treatments for inflammatory sino-nasal diseases, specifically focusing on chronic rhinitis. Neurent Medical offers a single-use, minimally invasive device designed for ENT surgeons, which utilizes a hand-held radio-frequency mechanism. This device is introduced through the nostrils into the nasal cavity under direct endoscopic visualization, where it deploys a microelectrode array to deliver targeted energy. This intervention interrupts the autonomic function of the mucosal structures in the nasal cavities, effectively reversing the inflammatory cascade. By enabling treatment in an office setting, Neurent Medical aims to eliminate the complications and costs typically associated with traditional surgical procedures for rhinitis.

Priothera Ltd is a clinical-stage biotechnology company based in Dublin, Ireland, with an additional location in Saint Louis, France. Founded in 2020, Priothera specializes in the development of orally administered sphingosine 1 phosphate (S1P) receptor modulators aimed at treating haematological malignancies. The company's leading candidate, mocravimod, is designed to reduce the egress of T cell subsets from lymphatic tissue, thereby enhancing the curative potential of allogeneic hematopoietic stem cell transplantation. By providing dual inhibition of graft versus host disease while promoting graft versus leukemia effects, Priothera aims to significantly improve outcomes for patients undergoing such transplants.

Neurent Medical Limited is a medical device company based in Galway, Ireland, founded in 2015 by Brian Shields and David Townley. The company specializes in developing non-surgical treatments for inflammatory sino-nasal diseases, specifically focusing on chronic rhinitis. Neurent Medical offers a single-use, minimally invasive device designed for ENT surgeons, which utilizes a hand-held radio-frequency mechanism. This device is introduced through the nostrils into the nasal cavity under direct endoscopic visualization, where it deploys a microelectrode array to deliver targeted energy. This intervention interrupts the autonomic function of the mucosal structures in the nasal cavities, effectively reversing the inflammatory cascade. By enabling treatment in an office setting, Neurent Medical aims to eliminate the complications and costs typically associated with traditional surgical procedures for rhinitis.

Mainstay Medical is a global medical device company based in Dublin, Ireland, with additional operations in the United States and Australia. The company specializes in developing innovative therapies for individuals suffering from chronic low back pain, a condition that affects a significant underserved population. Mainstay Medical has created an FDA-approved restorative treatment designed to enhance muscle control and improve functionality in the lumbar spine. This therapy aims to help patients regain mobility and enhance their overall quality of life. By collaborating with scientists and clinical experts, Mainstay Medical is committed to advancing solutions for those affected by debilitating back pain.

Inflazome Ltd. is a biotechnology company based in Dublin, Ireland, established in 2016. The company specializes in developing orally available drugs aimed at addressing unmet clinical needs in inflammatory diseases by targeting inflammasomes, which are critical in the inflammatory process. Inflazome's innovative therapies are designed to block inflammasome signals, thereby addressing the root causes of inflammation. The company's portfolio includes treatments for a range of conditions, such as neurological disorders like Alzheimer's and Parkinson's, systemic inflammatory diseases, and certain orphan diseases. As of September 2020, Inflazome operates as a subsidiary of Roche Holding AG, further enhancing its capacity to deliver targeted therapies in the field of inflammatory diseases.

Vivasure Medical Limited is a medical device company based in Galway, Ireland, that specializes in the research, development, and manufacture of arterial and venous closure devices utilizing its patented PerQseal technology. The company focuses on creating polymer implants and delivery systems aimed at minimally invasive vessel closures, primarily in cardiology, interventional radiology, and vascular surgery. Its flagship product is an absorbable patch-based large-bore percutaneous closure device, designed to effectively close large arteriotomies resulting from transcatheter procedures, including transcatheter aortic valve replacement and endovascular aneurysm repair. Founded in 2008, Vivasure Medical is committed to advancing techniques that enhance patient outcomes in vascular access procedures.

Opsona Therapeutics is a Dublin-based drug development company specializing in immunology, particularly the modulation of innate immunity pathways. Founded in 2004, the company has developed innovative therapeutic approaches aimed at treating autoimmune and inflammatory diseases, as well as cancer. By targeting the innate immune system, Opsona addresses a spectrum of significant health challenges, including transplant rejection, diabetes, Alzheimer's disease, and atherosclerosis. The company seeks to improve patient outcomes through its novel drug candidates and strategies, positioning itself as a leader in emerging immunology research and drug development in Europe.

Opsona Therapeutics is a Dublin-based drug development company specializing in immunology, particularly the modulation of innate immunity pathways. Founded in 2004, the company has developed innovative therapeutic approaches aimed at treating autoimmune and inflammatory diseases, as well as cancer. By targeting the innate immune system, Opsona addresses a spectrum of significant health challenges, including transplant rejection, diabetes, Alzheimer's disease, and atherosclerosis. The company seeks to improve patient outcomes through its novel drug candidates and strategies, positioning itself as a leader in emerging immunology research and drug development in Europe.

Mainstay Medical is a global medical device company based in Dublin, Ireland, with additional operations in the United States and Australia. The company specializes in developing innovative therapies for individuals suffering from chronic low back pain, a condition that affects a significant underserved population. Mainstay Medical has created an FDA-approved restorative treatment designed to enhance muscle control and improve functionality in the lumbar spine. This therapy aims to help patients regain mobility and enhance their overall quality of life. By collaborating with scientists and clinical experts, Mainstay Medical is committed to advancing solutions for those affected by debilitating back pain.

Cappella, Inc., a Dover, Del.- and Galway, Ireland-based medical device company that is developing novel solutions for the treatment of Complex Coronary Artery Disease (CAD) and specifically bifurcation vascular disease. The company was founded in 2004 by Antonio Columbo, M.D., Chief of Invasive Cardiology at San Raffaele Hospital in Milan, Italy, and Ascher Shmulewitz, M.D., Ph.D., a cardiologist, medical device entrepreneur and founder of NeoVision, Xcardia and Labcoat Ltd., and established its European headquarters in Galway in 2005.

Genable Technologies Limited is a bio-pharmaceutical company based in Dublin, Ireland, specializing in the development of gene therapies for autosomal dominant genetic diseases. The company focuses on innovative treatments for inherited disorders, notably its RhoNova product aimed at addressing rhodopsin (RHO)-linked autosomal dominant retinitis pigmentosa, a progressive form of inherited blindness caused by mutations in the RHO gene. Genable employs a unique approach that combines suppression and replacement of faulty gene copies using adeno-associated virus (AAV) vectors to deliver RNA interference (RNAi) molecules. This method allows the company to tackle the variability of mutations in dominant diseases without the need to target specific mutations. Genable Technologies was incorporated in 1998 and operates as a subsidiary of Spark Therapeutics, Inc. The company's technology is backed by a comprehensive portfolio of patents in the United States, Europe, and globally.

Amarin Corporation plc, a pharmaceutical company based in Dublin, Ireland, develops and markets therapeutics for cardiovascular disease treatment. Its primary product, Vascepa, is a prescription omega-3 fatty acid capsule used to lower triglyceride levels in adults with severe hypertriglyceridemia. Amarin also has a pipeline for REDUCE-IT, targeting patients with high triglyceride levels on statin therapy. The company sells its products through a direct sales force to wholesalers and specialty pharmacies, and collaborates with Mochida Pharmaceutical Co., Ltd. for further drug development. Amarin's expertise lies in lipid science and the therapeutic benefits of essential fatty acids in cardiovascular disease management.

Cappella, Inc., a Dover, Del.- and Galway, Ireland-based medical device company that is developing novel solutions for the treatment of Complex Coronary Artery Disease (CAD) and specifically bifurcation vascular disease. The company was founded in 2004 by Antonio Columbo, M.D., Chief of Invasive Cardiology at San Raffaele Hospital in Milan, Italy, and Ascher Shmulewitz, M.D., Ph.D., a cardiologist, medical device entrepreneur and founder of NeoVision, Xcardia and Labcoat Ltd., and established its European headquarters in Galway in 2005.

Opsona Therapeutics is a Dublin-based drug development company specializing in immunology, particularly the modulation of innate immunity pathways. Founded in 2004, the company has developed innovative therapeutic approaches aimed at treating autoimmune and inflammatory diseases, as well as cancer. By targeting the innate immune system, Opsona addresses a spectrum of significant health challenges, including transplant rejection, diabetes, Alzheimer's disease, and atherosclerosis. The company seeks to improve patient outcomes through its novel drug candidates and strategies, positioning itself as a leader in emerging immunology research and drug development in Europe.

Vivasure Medical Limited is a medical device company based in Galway, Ireland, that specializes in the research, development, and manufacture of arterial and venous closure devices utilizing its patented PerQseal technology. The company focuses on creating polymer implants and delivery systems aimed at minimally invasive vessel closures, primarily in cardiology, interventional radiology, and vascular surgery. Its flagship product is an absorbable patch-based large-bore percutaneous closure device, designed to effectively close large arteriotomies resulting from transcatheter procedures, including transcatheter aortic valve replacement and endovascular aneurysm repair. Founded in 2008, Vivasure Medical is committed to advancing techniques that enhance patient outcomes in vascular access procedures.