European Innovation Council

Chipiron develops portable MRI technology that uses quantum sensing to produce three-dimensional anatomical images at ultra-low magnetic fields. The devices are lightweight, portable, and priced at about one-tenth of conventional MRI systems. The technology supports disease detection, diagnosis, and treatment monitoring, with a focus on brain-related conditions, and aims to reduce fatality rates by expanding access to MRI imaging in diverse clinical settings.

AMT Medical B.V., established in 2015 and located in Ede, the Netherlands, specializes in the development of innovative medical devices for heart bypass surgery. The company's flagship product, the AMT Heart Bypass System, utilizes a minimal invasive technique known as the ELANA bypass, which was invented by neurosurgeon Prof. Dr. C.A.F. Tulleken and his research team. This advanced technology aims to enhance traditional heart bypass procedures by making them faster, safer, and less invasive, thereby improving patient outcomes and reducing complications. AMT Medical has completed the full development of its product and the production process, with all pre-clinical trials successfully concluded. The company is also preparing to initiate a clinical multi-center trial to further validate the technology's efficacy.

QDI Systems B.V. is a startup based in Groningen, the Netherlands, focused on developing advanced imaging devices for medical applications using quantum dot technology. The company specializes in creating X-ray sensors that deliver high-contrast and high-resolution imaging, particularly for mammography, while also reducing radiation exposure for patients. QDI Systems aims to provide user-friendly quantum dot materials accompanied by comprehensive instructions for constructing high-performance imaging devices. By leveraging innovative technology, the company enhances the precision of medical imaging, enabling healthcare professionals to obtain critical diagnostic information efficiently and safely.

QDI Systems B.V. is a startup based in Groningen, the Netherlands, focused on developing advanced imaging devices for medical applications using quantum dot technology. The company specializes in creating X-ray sensors that deliver high-contrast and high-resolution imaging, particularly for mammography, while also reducing radiation exposure for patients. QDI Systems aims to provide user-friendly quantum dot materials accompanied by comprehensive instructions for constructing high-performance imaging devices. By leveraging innovative technology, the company enhances the precision of medical imaging, enabling healthcare professionals to obtain critical diagnostic information efficiently and safely.

TENSIVE s.r.l. is a biomedical company based in Milan, Italy, founded in 2012. It specializes in the development of innovative prostheses for natural breast reconstruction and augmentation. The company's products utilize biodegradable synthetic biomaterials and feature an internal micro-architecture that mimics blood vessel structures. These vascularized prostheses aim to enhance the quality of life for patients undergoing treatment for breast cancer, offering a solution that reduces the need for recurrent and costly surgical interventions. Through its focus on advanced biomaterials and design, TENSIVE seeks to provide effective and sustainable options for breast reconstruction.

Dotlumen is a research startup founded in 2020 and based in Cluj, Romania, focused on enhancing the quality of life for visually impaired individuals. The company develops innovative glasses equipped with a sensory and feedback system that aids users in navigating their environments. By leveraging advancements in artificial intelligence, robotics, and neuroscience, Dotlumen aims to empower blind individuals to better understand and interact with the world around them.

Patient-specific right heart pumps that free patients from heavy battery packages and increase patient's quality of life.

Innoventric is an Israeli medical device company specializing in percutaneous solutions for Tricuspid Regurgitation and right heart disease. Founded in 2017, the company's flagship product is the Trillium™ technology, designed to treat Tricuspid Valve Regurgitation through functional valve replacement using Cross-Caval anchoring and a unique multi-valve design.

Inbrain Neuroelectronics is a medical device company that designs and commercializes graphene-based neural interfaces and intelligent neuromodulation systems to treat brain disorders. The core platform is an implantable system that decodes brain activity with high resolution and provides focal, adaptive stimulation, enabling real-time precision neurology and autonomous therapy adjustments. This approach aims to maximize therapeutic outcomes while minimizing side effects for conditions such as Parkinson’s disease, epilepsy, and stroke rehabilitation. The company pursues strategic collaborations to extend its solutions to peripheral nerve and systemic disease applications, expanding the potential of neurotechnology and bioelectronics.

Oryl Photonics specializes in developing laboratory instruments for pharmaceutical and biotech companies. Their core product provides a simple, reliable, and cost-effective method for measuring solubility, contributing to accelerated drug development and improved medicine. The company's unique technology preserves valuable substances during testing, offering a solubility measurement service that empowers researchers to make data-driven decisions and expedite product development.

Dotlumen is a research startup founded in 2020 and based in Cluj, Romania, focused on enhancing the quality of life for visually impaired individuals. The company develops innovative glasses equipped with a sensory and feedback system that aids users in navigating their environments. By leveraging advancements in artificial intelligence, robotics, and neuroscience, Dotlumen aims to empower blind individuals to better understand and interact with the world around them.

Endoron Medical develops a catheter-based device to secure endografts during endovascular aneurysm repair. The treatment uses a stapling mechanism that mimics hand-sewn suturing by deploying multiple staples around the aortic circumference to achieve transmural attachment of the stent graft to the aortic wall. The device aims to reduce endoleaks and graft migration and to enable treatment of complex abdominal aortic aneurysm anatomies by improving fixation and sealing of the endograft.

UroMems is a medical device company dedicated to addressing specific clinical needs related to urinary conditions that significantly impact patients' quality of life. The company specializes in the design, development, and commercialization of active implantable medical devices. Its innovative approach aims to enhance existing surgical treatments by minimizing associated side effects and ensuring that patients receive appropriate care promptly. Through its commitment to improving treatment options, UroMems seeks to benefit a wide range of patients facing urinary health challenges.

King's College London is a public research university in London, United Kingdom, and a constituent college of the University of London. Founded in 1829 by King George IV and the Duke of Wellington, it operates from multiple central London campuses and a campus in Denmark Hill, with a strong emphasis on medical and biomedical research and education. The institution supports a large community of students and staff and is known for its extensive graduate and postgraduate programmes. It is a founding member of the King's Health Partners academic health sciences centre and participates in major research and academic networks, including the Russell Group and Universities UK.

Vitestro develops autonomous blood drawing technology aimed at transforming patient care.

Vitestro develops autonomous blood drawing technology aimed at transforming patient care.

Sentante is a medical technology company specialising in the development of robotic teleoperated systems for endovascular procedures. Their core product enables physicians to perform complex surgeries remotely, reducing their exposure to harmful X-rays and expanding telesurgery capabilities.

Quantum Diamonds specializes in the development of nitrogen-vacancy (NV) diamonds for quantum sensing applications. The company designs advanced quantum sensors capable of measuring magnetic fields, temperature, and pressure, offering enhanced sensitivity and resolution compared to traditional sensors. These sensors enable a range of applications, including navigation, bio-imaging, geographical surveying, and spectroscopy, even under challenging conditions. Quantum Diamonds focuses on optimizing performance in areas such as crystal lattice strain, Rabi contrast, and charge state stability, catering to both industrial and academic customers seeking innovative solutions in quantum mechanics.

RespiQ is a healthtech company developing portable, non-invasive breath analysis technology that uses emission spectroscopy and artificial intelligence to detect biomarkers in breath for early identification and real-time monitoring of respiratory diseases such as COPD, as well as other conditions like asthma, lung cancer, and infectious diseases. Its device aims to be affordable and user-friendly, democratizing access to advanced diagnostics, while its platform can also identify digestive issues through breath biomarkers and support personalized guidance via an app that analyzes a digital breath print to deliver diet and health insights, enabling individuals to monitor changes and improve health outcomes.

Methinks is a developer of a medical imaging platform that leverages advanced artificial intelligence techniques to enhance the diagnosis of brain-related diseases, particularly acute stroke. Utilizing Google's deep learning framework, Tensorflow, Methinks analyzes neuroimaging data to facilitate accurate and timely diagnoses. The platform offers a significant advantage by enabling stroke assessments through non-contrast CT scans, thereby eliminating the need for contrast CT and reducing the time required for treatment. This innovative approach enhances communication between radiologists, hospitals, stroke units, and other healthcare professionals, ultimately aiming to improve clinical outcomes in stroke care.

NEOGAP Therapeutics is a clinical-stage biopharmaceutical startup focused on immuno oncology. Their pharmaceutical product, personalized tumor trained lymphocytes, offers even one customized cell treatment that is meant to precisely target and destroy cancer in a tailored environment, with very minor side effects.

Founded in 2014, Microsure specializes in enhancing microsurgical procedures. Its flagship product is a motion stabilizer system designed by and for microsurgeons to overcome physical limitations and improve surgical precision. This technology has successfully been used in clinical trials, with the aim of increasing treatment options for patients.

Innitius specializes in developing diagnostic devices aimed at enhancing women's health, particularly in the context of preterm birth. Utilizing innovative torsional ultrasound technology, the company has created a patented intravaginal probe that transmits torsional waves to assess changes in tissue consistency. This technology enables medical practitioners to evaluate the risk of preterm birth and the likelihood of successful labor induction. By providing actionable diagnostics, Innitius helps healthcare providers accurately identify false indications of premature labor, thereby improving patient care and outcomes in obstetrics.

Ligence is a Deep Tech startup based in Lithuania that combines medical expertise with artificial intelligence to automate echocardiography image analysis. The company develops tools for automatic recognition of heart image views, measurement, and report generation, accessible via a web-based platform and designed to integrate with hospital information systems. Its flagship solution, Ligence Heart, aims to reduce manual measurements by physicians and enhance consistency in heart ultrasound examinations through automated analysis. The offering targets clinicians and healthcare providers seeking to streamline cardiovascular imaging workflows.

RUBYnanomed provides non-invasive monitoring of cancer progression. They enable the analysis of their phenotypic, genetic, and functional characteristics, facilitating unprecedentedly frequent monitoring of cancer progression in a minimally invasive, cost-efficient way. They enable oncologists to detect and analyze the evolution of cancer subtypes and therapeutic resistance mechanisms in each patient, providing personalized therapy insights to treat their patients.

Xeltis is a clinical-stage medical device company developing bio-absorbable heart valves and blood vessels. Its RestoreX technology enables the body's natural healing system to create functional tissue within its devices, forming new valves or vessels over time. Headquartered in Zurich, Switzerland, with R&D and manufacturing facilities in Eindhoven, Netherlands, Xeltis aims to transform cardiovascular care.

Inbrain Neuroelectronics is a medical device company that designs and commercializes graphene-based neural interfaces and intelligent neuromodulation systems to treat brain disorders. The core platform is an implantable system that decodes brain activity with high resolution and provides focal, adaptive stimulation, enabling real-time precision neurology and autonomous therapy adjustments. This approach aims to maximize therapeutic outcomes while minimizing side effects for conditions such as Parkinson’s disease, epilepsy, and stroke rehabilitation. The company pursues strategic collaborations to extend its solutions to peripheral nerve and systemic disease applications, expanding the potential of neurotechnology and bioelectronics.

Rockfield Medical Devices is a forward-thinking small to medium enterprise focused on human-centered design within the medical device sector. Founded by an industry expert, the company comprises a team of recognized professionals from medical device research and design. Rockfield is dedicated to becoming a global leader in the enteral feeding market, aiming to enhance user satisfaction through innovative, plug-and-play technologies that prioritize design, usability, and mobility. The company's platform significantly improves the mobility and quality of life for individuals relying on tube feeding, while also streamlining technical support and reducing maintenance costs for sales partners. By offering a user-friendly, lightweight, and discreet mobile feeding system, Rockfield Medical Devices seeks to transform service models in the enteral feeding community.

Trisol Medical is a medical device company focused on addressing tricuspid regurgitation through innovative treatment solutions. The company specializes in the development of a transcatheter tricuspid replacement valve, which is engineered from a nitinol frame and features specially designed leaflets. This design effectively eliminates tricuspid regurgitation while preserving the function of the right ventricle. Trisol Medical's offerings aim to provide comprehensive treatment for patients suffering from tricuspid regurgitation and associated right ventricle dysfunction, enhancing patient outcomes and quality of life.

Cellbox Solutions is a technology company that specializes in innovative logistic solutions for the global BioMed industry. It has developed a carbon dioxide incubator designed for the storage, isolation, handling, and analysis of biological materials. This incubator offers essential logistic services and ensures the proper handling of living cells, facilitating their storage, reproduction, transportation, and analysis. By enabling the transportation of living cells via various methods, including road, rail, and air, Cellbox Solutions supports healthcare providers in their efforts to deliver the latest therapies to patients.

EBAMed develops a non-invasive ultrasound-based device to monitor and treat heart motion using proton beams. Founded in 2018, the company is based in Geneva, Switzerland.

Carthera is a clinical-stage medtech company focused on developing innovative ultrasound-based medical devices for treating brain disorders. Its proprietary device, SonoCloud®, is an intracranial ultrasound implant that, when used in conjunction with an intravenous microbubble agent, temporarily opens the blood-brain barrier. This mechanism significantly enhances the delivery of therapeutic molecules to the brain, potentially providing new treatment options for debilitating neurological conditions. Through its technology, Carthera aims to enable healthcare professionals to address challenging brain disorders more effectively.

Escala Medical is focused on developing a pioneering medical device aimed at treating pelvic organ prolapse (POP) in women. The company has created a minimally invasive, incision-free, and mesh-free repair system that addresses the long-standing need for effective POP treatment options. This innovative device allows for a nonsurgical approach that can be performed in outpatient and office settings, ensuring a safe and quick procedure with minimal discomfort for patients. By connecting the vaginal apex to the sacrospinous ligament without incisions, Escala Medical's technology preserves organ functionality while providing a much-needed solution for those affected by POP.

Escala Medical is focused on developing a pioneering medical device aimed at treating pelvic organ prolapse (POP) in women. The company has created a minimally invasive, incision-free, and mesh-free repair system that addresses the long-standing need for effective POP treatment options. This innovative device allows for a nonsurgical approach that can be performed in outpatient and office settings, ensuring a safe and quick procedure with minimal discomfort for patients. By connecting the vaginal apex to the sacrospinous ligament without incisions, Escala Medical's technology preserves organ functionality while providing a much-needed solution for those affected by POP.

Scandinavian Real Hearts is a medical technology company developing an artificial heart to address the needs of patients awaiting heart transplantation. Its Total Artificial Heart is designed to closely resemble the shape, function, and blood flow of the human heart, with the aim of serving as a bridging solution for transplant candidates.

AGADE specializes in robotic exoskeletons. Its flagship product, AGADEXO, significantly reduces muscle fatigue and injury risks associated with repetitive tasks by providing variable support, mimicking zero-gravity movements.

Tada Group AB, founded in 2016 and headquartered in Stockholm, Sweden, specializes in the manufacturing of medical products, primarily focusing on intravenous solutions. The company offers products such as the Thoor infusion tube, which is designed for efficiency in medical applications. Additionally, Tada Group has developed the ReLink connector, an innovative solution aimed at minimizing complications and costs related to accidental disconnections in IV lines, which is a significant issue in both hospital and homecare environments. Through its product offerings, Tada Group addresses critical challenges in healthcare, enhancing safety and reliability in infusion practices.

Founded in 2014, Bluedrop Medical develops an IoT-enabled device for early detection of diabetic foot ulcers. Its home-based system scans patients' feet daily, sends data to the cloud for analysis, and alerts healthcare providers to potential abnormalities, reducing amputation risks.

Nemysis is a Dublin-based specialty pharmaceutical company focused on developing and manufacturing food supplements, medical matrix products and prescription medicines. Founded in 2005, it pursues a staged development strategy to commercialize OTC and prescription products across different market segments addressing nutritional disorders and deficiencies. The company develops products such as a novel nanoparticulate oral iron supplement with a unique absorption mechanism to treat iron deficiency or anemia while minimizing gastrointestinal side effects, and glutenase capable of functioning in both the stomach and intestine to protect individuals with celiac disease or gluten sensitivity from inadvertent gluten exposure.

Sunrise is a medical technology company focused on improving the diagnosis and management of sleep disorders, particularly sleep apnea, which affects nearly one billion people worldwide. The company has developed a 3-gram sensor that allows for rapid and accurate at-home diagnosis of sleep conditions, utilizing trigeminal drive analysis to detect respiratory events. This innovative device is clinically validated for use in both adults and children and provides a cost-effective alternative to traditional in-lab sleep studies. Users receive a single-use sensor delivered to their home, which connects easily to their phone for seamless operation. Following the test, Sunrise facilitates consultations with certified sleep doctors or connections to local sleep centers, addressing a critical need in a healthcare landscape where 80% of sleep apnea cases remain undiagnosed.

Syntach is a medical technology company focused on developing innovative cardiac support devices aimed at enhancing the care of individuals suffering from heart failure. The company's flagship product is a permanent, active implant designed to restore the impaired movement of the mitral valve while providing natural support to the heart. This device can be inserted using minimally invasive techniques and is smaller than traditional left ventricular assist devices (LVADs), which contributes to a better quality of life for patients and reduces the risk of complications. Syntach's technology is intended to benefit both men and women who require cardiac support.

Ganymed Robotics is a medical device company that develops robotics technologies for orthopedic surgeons, including a therapeutic device designed to improve precision in knee replacement procedures. Founded in 2018 and based in Paris, the company aims to enhance surgical accuracy, reduce operating times, and improve patient outcomes by integrating robotics into the orthopedic workflow.

Sonio is an AI-based support platform for fetal ultrasound, helping practitioners analyze and diagnose congenital malformations. Sonio combines the patient’s medical history, genetic and biological data, and ultrasound semiology to assist physicians on the path to the right diagnosis. It assists sonographers during prenatal screening scans, helping them ensure that they have not forgotten anything, take risk factors into account, and facilitate the sharing of images with patients and other health professionals.

Sonio is an AI-based support platform for fetal ultrasound, helping practitioners analyze and diagnose congenital malformations. Sonio combines the patient’s medical history, genetic and biological data, and ultrasound semiology to assist physicians on the path to the right diagnosis. It assists sonographers during prenatal screening scans, helping them ensure that they have not forgotten anything, take risk factors into account, and facilitate the sharing of images with patients and other health professionals.

Dxcover is a clinical-stage liquid biopsy company based in Glasgow, established in 2016 by David S Palmer, Holly Butler, and Matthew Baker. The firm specializes in developing advanced diagnostics for the early detection of various cancers, focusing on Stage I and Stage II malignancies where timely intervention can significantly improve patient outcomes. Utilizing a combination of infrared spectroscopy and artificial intelligence, Dxcover's technology enables the detection of cancer from a simple blood sample, allowing for same-day diagnosis and patient stratification. This innovative approach aims to enhance treatment options and ultimately improve survival rates and quality of life for patients.

iThera Medical develops biomedical imaging technology based on photonic molecular imaging and multispectral optoacoustic tomography (MSOT) for preclinical and clinical applications. The company leverages the photoacoustic effect to visualize and quantify anatomical, functional, and molecular information in vivo, including deep tissue visualization and real-time imaging, enabling non-invasive assessment of tumors and inflammatory diseases. Founded in 2010 as a spin-off from Helmholtz Zentrum München, iThera Medical focuses on advancing MSOT technology for use in preclinical research and clinical trials, supporting researchers and clinicians in obtaining deeper insights into biological processes without invasive procedures.

Founded in 2018, Resistell develops and markets a diagnostic device for phenotypic antibiotic susceptibility testing. Its unique method detects movement caused by living bacterial cells to determine bacterial resistance to antibiotics.

Avatar Medical is a developer of a virtual reality medical platform that creates 3D patient avatars to assist surgeons in visualizing medical images. By generating interactive representations based on medical data, the platform enables clinicians to accurately and instantly access critical clinical information. This innovative approach not only enhances the understanding of surgical options but also facilitates the training of medical fellows and improves patient engagement. Avatar Medical aims to transform how medical professionals interact with imaging data, ultimately contributing to better surgical outcomes and patient care.

ABCDx is a Geneva-based company that develops and validates biomarker panels and related diagnostics for brain injury care. It aims to identify patients at risk of severe long-term complications after traumatic brain injury or stroke and to educate clinicians on using these tests. The company is building a platform that analyzes brain biomarkers from a finger-prick blood sample to enable rapid, point-of-care diagnosis of brain injuries, supporting timely treatment decisions. Founded in 2014 by researchers from the University of Geneva and related institutes, ABCDx translates biomarker discovery and clinical validation into practical tools for stroke and brain injury management.

Akknatek is an ophthalmology technology company developing postoperative monitoring and treatment solutions for intraocular lenses (IOLs). Its patented lens reviewer aids clinicians in deciding how to manage dislocated IOLs, with the aim of reducing post-operative refractive complications after cataract surgery and lowering the need for additional refractive procedures. The technology is designed to simplify postoperative management and support improved visual outcomes for patients undergoing cataract surgery.

CorWave is a company focused on developing innovative implanted cardiac support devices aimed at improving the quality of life for patients suffering from heart failure. Its flagship product, the CorWave LVAD, employs a unique undulating disc wave pumping mechanism, which replaces traditional high-speed impellers used in current continuous flow rotary pumps. This design significantly reduces trauma to blood, thereby minimizing complications such as clotting and bleeding. The CorWave pump generates a pulsatile flow that closely resembles the natural heartbeat, addressing a key limitation of existing LVADs that provide only continuous flow. Additionally, the device's low power consumption and compact size facilitate its potential for complete implantation, enhanced by a wireless energy transfer system. Through these advancements, CorWave aims to alleviate the burdens associated with heart failure and invasive surgical procedures.

Gold Standard Phantoms specializes in the development, marketing, and sale of calibration services and devices for quantitative medical imaging, particularly in the realm of MRI technology. The company manufactures cylindrical phantoms that streamline the preparation process by eliminating the need for multiple sample vials, facilitating more efficient calibration. Its offerings include a cloud-based data analysis platform that ensures traceability to standardized values, allowing clinicians, medical physicists, and radiographers to obtain consistent quantitative measurements of diseases across different patients, scanners, and clinical environments. By enhancing the precision of MRI imaging, Gold Standard Phantoms aims to improve diagnostic accuracy and potentially reduce healthcare costs.

Carmat is a French medtech company that specializes in the development and manufacturing of bioprosthetic artificial hearts. Founded in 2008 and headquartered in Vélizy-Villacoublay, the company creates biocompatible, auto-regulated total artificial hearts designed to closely mimic the human heart's structure, including both right and left ventricles. These devices are intended for patients suffering from chronic terminal heart failure classified as class IV by the New York Heart Association, as well as those experiencing acute terminal heart failure due to massive myocardial infarction. Carmat aims to provide a reliable and innovative therapeutic solution for heart failure patients who are ineligible for transplants and have exhausted other treatment options. In addition to the artificial hearts, the company develops the necessary power supply systems and remote diagnostic systems for these devices.

timeisbrain is a medical device for improving the diagnostics and prognostics of acute ischaemic stroke

ELEM Biotech SL is a biomedical software company based in Barcelona, Spain, that specializes in creating virtual human models through advanced mathematical modeling and cloud computing. Founded in 2018 by researchers from the Barcelona Supercomputing Center, ELEM has developed a suite of simulation tools known as Alya Red. This platform operates on a Software-as-a-Service model and is designed for the medical device and pharmaceutical industries. Alya Red allows for the simulation of cardiovascular and respiratory systems on virtual patients, utilizing high-performance computing, computational biomechanics, and data analysis. These virtual avatars enable biomedical companies and healthcare professionals to enhance diagnostics, plan treatments, optimize drug delivery, and improve medical devices.

Vigor Medical Technologies Ltd. develops innovative devices for treating chest trauma and managing thoracic/abdominal drainage. Its self-fixation sealing devices prevent lung and heart collapse, reducing fatality rates associated with chest trauma, which affects over 4 million people worldwide annually.

Founded in 2018, Axiles Bionics is a Belgian company specializing in the manufacture of robotic ankle-foot prosthetics. Their primary product is a bionic foot designed to enhance mobility for lower limb amputees.

Inbrain Neuroelectronics is a medical device company that designs and commercializes graphene-based neural interfaces and intelligent neuromodulation systems to treat brain disorders. The core platform is an implantable system that decodes brain activity with high resolution and provides focal, adaptive stimulation, enabling real-time precision neurology and autonomous therapy adjustments. This approach aims to maximize therapeutic outcomes while minimizing side effects for conditions such as Parkinson’s disease, epilepsy, and stroke rehabilitation. The company pursues strategic collaborations to extend its solutions to peripheral nerve and systemic disease applications, expanding the potential of neurotechnology and bioelectronics.

Afon Technology specializes in the development of non-invasive blood glucose monitoring devices aimed at benefiting individuals with diabetes. The company’s innovative technology allows for real-time, pain-free tracking of blood glucose levels, offering features such as continuous detection, potential pre-diabetic identification, and alarm alerts for high and low glucose levels. Users can access trend profiles and time-in-range statistics through a user-friendly app compatible with both iOS and Android systems. Additionally, Afon Technology’s device can transform any smartwatch into a glucose monitoring tool, providing fast and accurate measurements, data logging, and personalized health trends. This approach enhances daily management for diabetics, ultimately reducing the risk of diabetes-related complications.

Newronika develops innovative neuro-modulation devices aimed at restoring brain and body functions. The company translates its deep expertise in biosignal decoding into clinical practice, enabling patients to receive targeted stimulation for improved daily activities and enhanced quality of life.

Carmat is a French medtech company that specializes in the development and manufacturing of bioprosthetic artificial hearts. Founded in 2008 and headquartered in Vélizy-Villacoublay, the company creates biocompatible, auto-regulated total artificial hearts designed to closely mimic the human heart's structure, including both right and left ventricles. These devices are intended for patients suffering from chronic terminal heart failure classified as class IV by the New York Heart Association, as well as those experiencing acute terminal heart failure due to massive myocardial infarction. Carmat aims to provide a reliable and innovative therapeutic solution for heart failure patients who are ineligible for transplants and have exhausted other treatment options. In addition to the artificial hearts, the company develops the necessary power supply systems and remote diagnostic systems for these devices.

CorTec specializes in developing innovative medical devices for neuromodulation and brain-computer interfaces. Its flagship product is the CorTec Brain Interchange™ System, featuring flexible electrode arrays and a hermetically sealed electronics unit with custom microchip technology. The system enables permanent brain recordings and stimulation without the need for battery replacement surgery.

TENSIVE s.r.l. is a biomedical company based in Milan, Italy, founded in 2012. It specializes in the development of innovative prostheses for natural breast reconstruction and augmentation. The company's products utilize biodegradable synthetic biomaterials and feature an internal micro-architecture that mimics blood vessel structures. These vascularized prostheses aim to enhance the quality of life for patients undergoing treatment for breast cancer, offering a solution that reduces the need for recurrent and costly surgical interventions. Through its focus on advanced biomaterials and design, TENSIVE seeks to provide effective and sustainable options for breast reconstruction.

CYTO365 manufactures RondelO multi inlet stopcocks, designed to integrate into IV-sets to prevent drug incompatibility due to parallel infusion.

Inbrain Neuroelectronics is a medical device company that designs and commercializes graphene-based neural interfaces and intelligent neuromodulation systems to treat brain disorders. The core platform is an implantable system that decodes brain activity with high resolution and provides focal, adaptive stimulation, enabling real-time precision neurology and autonomous therapy adjustments. This approach aims to maximize therapeutic outcomes while minimizing side effects for conditions such as Parkinson’s disease, epilepsy, and stroke rehabilitation. The company pursues strategic collaborations to extend its solutions to peripheral nerve and systemic disease applications, expanding the potential of neurotechnology and bioelectronics.

ValueBiotech Srl is a medical device company focused on developing robotic surgical tools that enhance laparoscopic techniques. Designed by practicing surgeons, these innovative tools integrate seamlessly into operating rooms, enabling surgeons to perform procedures through a single incision or natural orifices, resulting in a painless and scarless experience for patients. The company's mission is to improve clinical outcomes while ensuring safety and cost-effectiveness in surgical practices. By transforming traditional surgical methods, ValueBiotech aims to provide better healthcare solutions for millions of patients each year.

Alesi Surgical Ltd. is a company based in Cardiff, United Kingdom, specializing in the development and commercialization of laparoscopic surgical smoke handling systems. Founded in 2009 as a spin-out from the Welsh Institute for Minimal Access Therapy, Alesi Surgical focuses on creating products that enhance the safety, efficiency, and outcomes of surgical procedures. Its innovative tools are portable and suitable for both laparoscopic and robot-assisted surgeries, utilizing electrostatic precipitation technology to eliminate surgical smoke and maintain a clear visual field during operations. The company distributes its products to hospitals across Europe, the Middle East, New Zealand, and Australia, leveraging its access to experienced surgeons and surgical trainers to identify challenges in surgical procedures and design effective solutions.

Precisis is a medical technology company founded in 2004 and headquartered in Heidelberg, Germany, focused on developing innovative devices for epilepsy treatment. The company designs a brain-computer interface device that delivers individualized brain stimulation by positioning beneath the scalp over the epileptic focus. The device enables deep, targeted stimulation of the affected brain region without direct contact with the skull or skull penetration, aiming to improve seizure control and quality of life for patients with epilepsy through precise anatomical targeting.

Novus Diagnostics develops a point-of-care diagnostic system for infectious diseases, including a sample-to-answer sepsis platform that rapidly detects and classifies pathogens in whole blood. The device provides automated pathogen identification within minutes from a blood sample, allowing healthcare providers to diagnose sepsis-related infections and initiate timely, cost-effective treatment.

FEops is a pioneering company specializing in physics-based simulations for minimally invasive cardiovascular devices and procedures. It develops advanced cardiac imaging technology that enhances personalized treatment for patients with structural heart disease. By providing artificial intelligence-enabled anatomical analyses, FEops generates data-driven insights that facilitate improvements in transcatheter valve procedures. The company collaborates with medical device developers and healthcare professionals, offering valuable simulations that accelerate research and development processes while ensuring device safety. Physicians benefit from these patient-specific insights, which enhance their efficiency and ultimately lead to improved clinical outcomes and patient safety.

Lattice Medical is a French medical device company focused on breast reconstruction after cancer. It designs and manufactures implantable devices that promote regeneration of autologous adipose tissue to enable natural breast reconstruction following mastectomy. The flagship implant, MATTISSE, uses 3D printing and fully biodegradable materials to provide personalized reconstruction in a single surgery, reducing operative time and invasiveness. The company aims to offer an alternative to silicone-based implants by supporting tissue regeneration rather than replacement. Founded in 2017 and based in Loos, France, Lattice Medical develops solutions to address clinical and societal needs by restoring form and function for women recovering from breast cancer.

Positrigo develops and manufactures dedicated brain positron emission tomography (PET) scanners. Its mission is to make functional brain imaging accessible for early detection of neurodegenerative diseases like Alzheimer's, Lewy body dementia, vascular dementia, and frontotemporal dementia.

Ostoform is a Dublin, Ireland-based medical device company focused on ostomy skin health. It develops patented devices designed to manage skin complications for ostomy patients, including OSTOFORM, a mouldable seal that wraps around the stoma, and FLOWASSIST, which directs stoma output away from the skin. The technology is designed to prevent skin contact with corrosive output, reduce leakage, and improve skin health. The business originated as a spin-out from the University of Limerick and was established in 2016, leveraging patented technology to scale its solutions globally.

Fineheart is a France-based medical device company specializing in innovative technologies for cardiovascular care. It focuses on the development of implantable cardiac devices aimed at treating cardiovascular diseases. The company's flagship product is a novel, wirelessly powered, fully implantable mechanical circulatory support device. This device is designed to optimize cardiac output while preserving the heart's natural contractility, thereby enabling patients to restore normal cardiac function. Fineheart's technology aims to improve the quality of life for heart failure patients, allowing them to return to normal daily activities.

Fineheart is a France-based medical device company specializing in innovative technologies for cardiovascular care. It focuses on the development of implantable cardiac devices aimed at treating cardiovascular diseases. The company's flagship product is a novel, wirelessly powered, fully implantable mechanical circulatory support device. This device is designed to optimize cardiac output while preserving the heart's natural contractility, thereby enabling patients to restore normal cardiac function. Fineheart's technology aims to improve the quality of life for heart failure patients, allowing them to return to normal daily activities.

AVVie GmbH is a medical device startup that specializes in developing minimally invasive implants for heart valve repair, specifically targeting mitral regurgitation. This condition arises when the mitral valve leaflets fail to close properly, potentially leading to serious heart complications over time. The flagship product, the Mitral Butterfly® implant, is designed to be deployed via catheter, allowing for the repair of the mitral valve without the need for open-heart surgery. This innovative approach not only shortens hospitalization times but also expands treatment options for patients who may not be suitable candidates for traditional surgeries. The implant features a one-stage delivery system and a design that allows the leaflets to function normally after implantation, significantly improving upon existing solutions. The procedure to repair the valve is efficient, taking less than 12 minutes, and utilizes a combination of a nitinol stent and a polymer matrix to mimic conventional chordal repair techniques.

Methinks is a developer of a medical imaging platform that leverages advanced artificial intelligence techniques to enhance the diagnosis of brain-related diseases, particularly acute stroke. Utilizing Google's deep learning framework, Tensorflow, Methinks analyzes neuroimaging data to facilitate accurate and timely diagnoses. The platform offers a significant advantage by enabling stroke assessments through non-contrast CT scans, thereby eliminating the need for contrast CT and reducing the time required for treatment. This innovative approach enhances communication between radiologists, hospitals, stroke units, and other healthcare professionals, ultimately aiming to improve clinical outcomes in stroke care.

Orixha is a medical technology company focused on developing an innovative device that enhances patient cooling in critical situations, particularly after cardiac arrest. The device employs a specialized liquid ventilator that utilizes perfluorocarbons to fill the lungs, effectively transforming them into a highly efficient heat exchange chamber. This method allows for rapid cooling of the patient, thereby improving their prognosis by protecting vital organs from damage associated with reperfusion. By leveraging the unique properties of the liquid and the extensive surface area of the lungs, Orixha aims to provide a significant advancement in post-cardiac arrest care.

Nanordica Medical is an Estonian medical technology company that develops wound care solutions based on patented nanotechnology, combining copper and silver in nanofibers to remove infection and support healing in chronic wounds. The company has launched a veterinary wound dressing and is developing a first-in-class human dressing for hard-to-heal wounds such as diabetic foot ulcers. Clinical data suggest superior efficacy of the Nanordica dressing compared with conventional silver-based dressings. The underlying technology uses silver nanoparticles blended with other components to broaden antibacterial activity, including against drug-resistant strains.

Akknatek is an ophthalmology technology company developing postoperative monitoring and treatment solutions for intraocular lenses (IOLs). Its patented lens reviewer aids clinicians in deciding how to manage dislocated IOLs, with the aim of reducing post-operative refractive complications after cataract surgery and lowering the need for additional refractive procedures. The technology is designed to simplify postoperative management and support improved visual outcomes for patients undergoing cataract surgery.

CYTO365 manufactures RondelO multi inlet stopcocks, designed to integrate into IV-sets to prevent drug incompatibility due to parallel infusion.

neuroClues develops AI-driven eye-tracking technology for clinical use that quantifies neurological function during exams. The platform provides an easy-to-use eye-tracking environment enabling clinicians to assess brain health non-invasively and monitor neurological conditions. By applying AI to eye movement data, the company aims to enable earlier detection of neurological disorders such as Parkinson's and Alzheimer's disease, potentially improving patient outcomes and informing treatment decisions. The approach offers a non-invasive diagnostic aid that can complement traditional assessments and support streamlined clinical workflows.

timeisbrain is a medical device for improving the diagnostics and prognostics of acute ischaemic stroke

timeisbrain is a medical device for improving the diagnostics and prognostics of acute ischaemic stroke

Innitius specializes in developing diagnostic devices aimed at enhancing women's health, particularly in the context of preterm birth. Utilizing innovative torsional ultrasound technology, the company has created a patented intravaginal probe that transmits torsional waves to assess changes in tissue consistency. This technology enables medical practitioners to evaluate the risk of preterm birth and the likelihood of successful labor induction. By providing actionable diagnostics, Innitius helps healthcare providers accurately identify false indications of premature labor, thereby improving patient care and outcomes in obstetrics.

ABCDx is a Geneva-based company that develops and validates biomarker panels and related diagnostics for brain injury care. It aims to identify patients at risk of severe long-term complications after traumatic brain injury or stroke and to educate clinicians on using these tests. The company is building a platform that analyzes brain biomarkers from a finger-prick blood sample to enable rapid, point-of-care diagnosis of brain injuries, supporting timely treatment decisions. Founded in 2014 by researchers from the University of Geneva and related institutes, ABCDx translates biomarker discovery and clinical validation into practical tools for stroke and brain injury management.

ELEM Biotech SL is a biomedical software company based in Barcelona, Spain, that specializes in creating virtual human models through advanced mathematical modeling and cloud computing. Founded in 2018 by researchers from the Barcelona Supercomputing Center, ELEM has developed a suite of simulation tools known as Alya Red. This platform operates on a Software-as-a-Service model and is designed for the medical device and pharmaceutical industries. Alya Red allows for the simulation of cardiovascular and respiratory systems on virtual patients, utilizing high-performance computing, computational biomechanics, and data analysis. These virtual avatars enable biomedical companies and healthcare professionals to enhance diagnostics, plan treatments, optimize drug delivery, and improve medical devices.

Founded in 2018, Axiles Bionics is a Belgian company specializing in the manufacture of robotic ankle-foot prosthetics. Their primary product is a bionic foot designed to enhance mobility for lower limb amputees.

CorTec specializes in developing innovative medical devices for neuromodulation and brain-computer interfaces. Its flagship product is the CorTec Brain Interchange™ System, featuring flexible electrode arrays and a hermetically sealed electronics unit with custom microchip technology. The system enables permanent brain recordings and stimulation without the need for battery replacement surgery.

AcouSort develops and sells laboratory equipment and integrated solutions using ultrasound to separate, wash, and enrich cells, exosomes, and other biological particles for research and diagnostics.

Selio Medical is a medical device company focused on reducing pneumothorax during lung biopsies. It develops a single-use device with a novel needle technology that temporarily seals the needle access route into the lung before biopsy, enabling interventional radiologists to perform procedures more safely and efficiently. The technology is protected by patents, and prototypes have been validated in laboratory tests and preclinical in vivo studies with positive results.

AMT Medical B.V., established in 2015 and located in Ede, the Netherlands, specializes in the development of innovative medical devices for heart bypass surgery. The company's flagship product, the AMT Heart Bypass System, utilizes a minimal invasive technique known as the ELANA bypass, which was invented by neurosurgeon Prof. Dr. C.A.F. Tulleken and his research team. This advanced technology aims to enhance traditional heart bypass procedures by making them faster, safer, and less invasive, thereby improving patient outcomes and reducing complications. AMT Medical has completed the full development of its product and the production process, with all pre-clinical trials successfully concluded. The company is also preparing to initiate a clinical multi-center trial to further validate the technology's efficacy.

Ganymed Robotics is a medical device company that develops robotics technologies for orthopedic surgeons, including a therapeutic device designed to improve precision in knee replacement procedures. Founded in 2018 and based in Paris, the company aims to enhance surgical accuracy, reduce operating times, and improve patient outcomes by integrating robotics into the orthopedic workflow.

AVertto is a medical device manufacturer specializing in telemonitoring technology. Its primary product is an AI-powered device designed to detect and alert healthcare providers about changes in blood flow and physiological parameters, focusing on signal analysis of carotid pulse waves.

Restore Medical develops a device-based therapy for congestive heart failure. Its product, ContraBand, is a catheter-delivered implant in the pulmonary arteries designed to improve patient quality of life and reduce hospital readmission rates.

Ovagen is a biotechnology company specializing in the commercial production of germ-free chicken eggs and birds. Primarily serving the pharmaceutical industry, Ovagen offers contract research services and expertise in specific poultry and rodent research technologies to Good Manufacturing Practice (GMP) standards.

Orixha is a medical technology company focused on developing an innovative device that enhances patient cooling in critical situations, particularly after cardiac arrest. The device employs a specialized liquid ventilator that utilizes perfluorocarbons to fill the lungs, effectively transforming them into a highly efficient heat exchange chamber. This method allows for rapid cooling of the patient, thereby improving their prognosis by protecting vital organs from damage associated with reperfusion. By leveraging the unique properties of the liquid and the extensive surface area of the lungs, Orixha aims to provide a significant advancement in post-cardiac arrest care.

Lindhe Xtend is a company specializing in the development and sale of user-friendly, flexible prostheses and accessories. Committed to enhancing the quality of life for amputees, Lindhe Xtend designs its products with the goal of enabling users to lead active and independent lives. The company's prosthetics are crafted from composite materials, allowing for adaptability to uneven terrain and various daily situations. By collaborating closely with users during the design process, Lindhe Xtend ensures that its solutions are tailored to meet the real needs of individuals, ultimately promoting freedom of movement and a more natural lifestyle.

GlucoSet is a medical device company developing sensor technology for improved glucose control in intensive care units. Its intravascular blood glucose monitoring system provides continuous and accurate readings, enabling clinicians to normalize glucose levels and reduce harmful hypoglycemia, thereby lowering mortality rates, complications, and healthcare costs.

PhosPrint, established in 2019 and headquartered in Agia Paraskevi, Attiki, specializes in laser bioprinting systems and regenerative medicine. The company's core business involves developing and providing on-site cell printing during surgeries, aiming to facilitate tissue regeneration and advance medical research. PhosPrint's offerings include healthcare technology products that leverage laser bioprinting and biotechnology research, enabling researchers and medical professionals to access innovative tools and procedures to combat diseases and medical conditions.