Yale University Investments serves as the endowment arm of Yale University, managing a diverse array of investment portfolios that encompass public equity, fixed income, alternative investments, private equity, and real estate. Established in 1973 and headquartered in New Haven, Connecticut, the organization employs both fundamental and quantitative analyses to build its portfolios, primarily focusing on value stocks to enhance returns. To mitigate risk, it diversifies investments across global markets and various asset classes, including absolute return securities. The performance of its portfolios is benchmarked against several prominent indices. The endowment's earnings play a crucial role in supporting the university's academic mission by funding scholarships, professorships, fellowships, and research initiatives, all overseen by the Yale Corporation Investment Committee and an executive management team with significant investment expertise.
Behaivior LLC is a digital health company based in Pittsburgh, Pennsylvania, focused on predicting and preventing addiction relapses through innovative technology. Founded in 2017, Behaivior develops a platform that combines wearable devices and machine learning algorithms to monitor key physiological signals such as heart rate and motion. This system, known as Recovery, is designed to support mental health recovery and wellness by delivering timely interventions based on real-time data. By utilizing a software-as-a-service (SaaS) model, Behaivior empowers individuals to maintain their recovery process while enabling care providers to better assist their clients. The integration of AI and behavioral health technology allows Behaivior to recognize patterns in human behavior, ultimately aiming to enhance mental well-being and reduce the incidence of crises, including relapse.
Banofi Leather
Grant in 2023
Banofi Leather is to protect our only planet, by creating plant-based leather from banana crop waste. Banofi believe that customers should not have to compromise but also that fashion should be guilt and cruelty-free. So, we dedicated ourselves to creating Banofi, which looks, feels, and smells like traditional leather.
Coral Vita
Seed Round in 2021
Coral Vita Inc. is a reef restoration company based in San Diego, California, focused on protecting and restoring vulnerable coral reefs affected by climate change. Founded in 2015, the company specializes in coral farming, where it grows diverse and resilient corals in land-based farms. This innovative approach allows for the cultivation of corals that are better equipped to thrive in changing ocean conditions. Coral Vita transplants these resilient corals into degraded reefs, employing advanced techniques to enhance growth rates and bolster their resistance to warming and ocean acidification. By providing tailored reef restoration plans, Coral Vita aims to address the urgent challenges facing coral ecosystems while promoting biodiversity and marine health.
Forested
Pre Seed Round in 2020
Forested is an agroforestry enterprise focused on combating deforestation through partnerships with forest communities. The company specializes in regeneratively growing, processing, and marketing specialty non-timber forest products. By collaborating with smallholder farmers, Forested strengthens natural ingredient supply chains while providing producers with guaranteed markets and premium prices for their products. This approach enables farmers living near forest edges to sustainably cultivate agricultural products that thrive in forest ecosystems, thereby promoting climate neutrality and enhancing social equity. With a multidisciplinary team possessing extensive experience in agroforestry, Forested is dedicated to fostering a nature-positive and economically viable future for both communities and the environment.
IvyTech Design
Seed Round in 2020
IvyTech Design was founded with a mission to develop adjustable-angle orthopedic instruments that can distract, align, and compress bones more precisely than current tools. Our patented and patent-pending technology addresses key challenges in foot and spine procedures, which suffer from high complication rates (up to 20-25%), costly revision surgeries, and suboptimal patient outcomes. IvyTech Design’s instruments will enable surgeons to precisely angle bones, providing superior alignment and access in foot and spine operations. Surgeons, hospitals, and patients will all benefit from this technology, as we aim to lower complication and revision rates, reduce surgical times, and improve patient outcomes.
Thermaband
Pre Seed Round in 2020
Thermaband is a company focused on addressing menopause through innovative technology and community support. Founded by Debbie and Markea Dickinson, the business emerged from their own frustrations with ineffective cooling solutions for hot flashes, a common challenge faced by many women, particularly women of color. Thermaband's flagship product, the Zone device, is a smart wrist-wearable that uses sensors and machine learning algorithms to monitor body temperature and adjust cooling or heating sensations accordingly. This device aims to provide immediate comfort while empowering women to manage their menopausal symptoms effectively. Accompanying the device is the Zone App, which offers personalized insights into thermal wellness, enhancing the user experience through a digital subscription model that fosters community and support. By combining technology with a holistic approach, Thermaband seeks to improve the quality of life for women navigating this significant life stage.
Neurotype
Pre Seed Round in 2019
Neurotype is a medical device company dedicated to addressing the challenges of addiction, particularly the environmental triggers that can lead to drug cravings and relapse. Its flagship product, the NeuromarkR platform, consists of a headset and accompanying software that objectively measures brain signatures associated with drug cravings. This innovative technology aims to enhance treatment for individuals recovering from addiction by identifying specific triggers linked to their past drug use. Neurotype's approach incorporates tailored psychotherapy strategies, including Cognitive Behavioral Therapy and Mindfulness-Based Treatment, to provide targeted interventions that help patients manage their cravings more effectively. By focusing on the underlying brain circuits involved in addiction, Neurotype seeks to improve mental and behavioral healthcare for those affected by substance use disorders.
RxAll
Grant in 2017
RxAll is a Deep Learning-Hyperspectral IoT Platform for instant authentication and real-time global tracking of quality of drugs- prescription & OTC meds., opioids, recreational drugs and cannabis- through mobile phones and a cloud based platform. We deliver authenticated medicines to hospitals, pharmacies and patients.
Verb Energy
Grant in 2017
Verb Energy, Inc. is a manufacturer of caffeinated energy bars founded in 2015 and based in Lexington, Massachusetts. The company focuses on creating simple, healthy, and delicious energy products that cater to a wide audience. Its flagship offering, the Verb Caffeinated Energy Bar, incorporates caffeine sourced from organic green tea, combined with carbohydrates and protein to ensure prolonged caffeine absorption. This formulation aims to provide consumers with a convenient and effective source of long-lasting energy at an affordable price. Verb Energy emphasizes the importance of health and taste in its products, making them suitable for everyday consumption.
Tonebase
Grant in 2017
tonebase gives you access to educational content produced by the world's greatest musicians and music educators. By giving everyone access to the world's greatest musical minds, tonebase hopes to democratize music education. https://tonebase.co/
Saphlux
Seed Round in 2015
Saphlux, Inc. is a company focused on the development, production, and commercialization of semi-polar gallium nitride (GaN) materials and micro-LED technologies. Founded in 2014 and headquartered in New Haven, Connecticut, Saphlux addresses key issues in the LED and laser industries, such as droop and green gap problems, by offering semi-polar GaN templates in various sizes. Additionally, Saphlux is a pioneer in quantum dot (QD) micro-LED solutions, designing and manufacturing micro-LED chips and micro-display modules for diverse applications, including automotive displays and augmented reality glasses. Their current product offerings include the NPQD R1 chip for public information displays and the NPQD T1 micro-display for AR applications. Operating globally, Saphlux has established a presence in the United States, China, and Japan, aiming to enhance the efficiency and performance of LED products while maintaining competitive pricing.
New Haven Pharmaceuticals
Series B in 2014
New Haven Pharmaceuticals (NHP) is a specialty pharmaceuticals company focused on developing proprietary prescription medications that leverage currently marketed drugs and generally recognized as safe (GRAS) active pharmaceutical ingredients for therapeutic applications with substantial market potential. The company is advancing a product pipeline that features innovative, oral, controlled-release technologies, enhancing dosing accuracy, safety, efficacy, and patient convenience. NHP's research is supported by intellectual property licensed from Yale University, allowing for the development of new therapeutic indications using established compounds.
IsoPlexis
Series A in 2014
IsoPlexis is a life science technology company based in Branford, Connecticut, founded in 2013. It focuses on developing a single-cell detection system that identifies patient immune responses at the single-cell level. This innovative platform enables the assessment of therapeutic safety and efficacy, as well as the monitoring of disease progression. IsoPlexis specializes in cell-based proteomic systems and biomarkers, providing insights into functional protein biology and cellular signaling networks with high resolution. By offering these capabilities, the company aids in predicting patient responses to novel immunotherapies and cellular therapies, ultimately enhancing therapeutic development and informing clinical decisions.
New Haven Pharmaceuticals
Series A in 2012
New Haven Pharmaceuticals (NHP) is a specialty pharmaceuticals company focused on developing proprietary prescription medications that leverage currently marketed drugs and generally recognized as safe (GRAS) active pharmaceutical ingredients for therapeutic applications with substantial market potential. The company is advancing a product pipeline that features innovative, oral, controlled-release technologies, enhancing dosing accuracy, safety, efficacy, and patient convenience. NHP's research is supported by intellectual property licensed from Yale University, allowing for the development of new therapeutic indications using established compounds.
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