Temasek Holdings

Temasek Holdings, established in 1974 and based in Singapore, is an investment company managing a diversified portfolio valued at approximately S$242 billion. The firm actively invests across various sectors, including telecommunications, media and technology, financial services, transportation, consumer products, real estate, life sciences, and energy. Temasek focuses on long-term investment themes such as transforming economies, growing middle-income populations, deepening comparative advantages, and supporting emerging champions. Its investment strategy encompasses a combination of liquid assets, listed and unlisted equities, and private equity opportunities, with a notable emphasis on mid-stage technology and life sciences investments through its private equity arm, Temasek Capital Management. Furthermore, Temasek aims to be the preferred investor for companies in Singapore and internationally, reflecting its commitment to global investment opportunities.

Pradyumna Agrawal

Director

Soyoun Ahn

Managing Director, Investment (Credit and Hybrid Solutions)

Gary Ang

Managing Director, Macro Strategy

Parimal Aswani

Managing Director, Technology

Ravi Balasubramanian

Managing Director, Portfolio Development, New Energy and Industrials

Siddartha Bhattacharjee

Head of Mobility and Logistics and Managing Director of Portfolio Strategy & Risk Group

Eric Bielke

Director

Wendy Chandra

Managing Director, Technology

Yuliang Chang

Managing Director, Investment (China)

Eu Chua

Managing Director, Institutional Relations and Singapore Market

Ranjit Dandekar

Managing Director, Investment

Promit Ghosh

Managing Director

Reena Kanagasingam

Managing Director, Investment (Public Markets)

Ming Pey Lim

Chief of Staff, Executive Office, Deputy Chief Corporate Officer and Managing Director, Strategy Office

Sheau Ming Lim

Director

Paul Liu

Managing Director, Investment (Financial Services), Portfolio Strategy and Risk Group

Anuj Maheshwari

Head, Agri-Food Managing Director, Investment (Middle East and Africa)

Nicolas Meier

Managing Director, Investment (EMEA) and Director

Jingwen Miao

Managing Director, Investment (China)

Suranjan Mukherjee

Managing Director, Cross Asset Macro Portfolio and Joint Head, Public Market Investment Strategies

Jonathan Popper

Managing Director, Portfolio Development Group

Ryan Rakestraw

Director

Parangam Ray

Managing Director, Organisation and People

Pierce Scranton

Managing Director, Institutional Relations and Deputy Head, North America

Shaun Seow

Managing Director, Singapore Market and Head, Community Stewardship

Rohit Sobti

Managing Director, New Energy and Industrials

Jason Sun

Chief Representative, Beijing and Managing Director, Investment (China)

Belinda Tan

Managing Director, Finance (Financial Management)

Man-Keung Tang

Managing Director, Macro Strategy

Sulian Tay

Operating Partner

Alan Thompson

Operating Partner

Karen Toh

Managing Director, Finance (Treasury)

Damien Vacherot

Director

Benoit Valentin

Senior Managing Director EMEA and Head of Private Equity Fund Investments

Rob Williams

Managing Director, Investment (EMEA)

Ye Xu

Managing Director, Investment (China)

Past deals in Life Science

Molbio Diagnostics

Venture Round in 2022
Molbio Diagnostics Private Limited manufactures and distributes medical appliances, instruments, and appliances for measuring, checking, testing, navigating, and other purposes. The company products include Truelab; real-time quantitative micro PCR and micro PCR printer, Truenat; chip-based real-time PCR test for mycobacterium tuberculosis, and Trueprep; pre-treatment pack for non-MTB samples. Molbio Diagnostics Private Limited was founded in 2000 and is based in Verna, India with additional offices in Goa, West Bengal, Delhi, Maharashtra, Tamil Nadu, and Karnataka.

Brightseed

Series B in 2022
Brightseed, Inc. is a biotechnology company that specializes in discovering clinically beneficial molecules found in plants through its innovative Forager platform. Founded in 2017 and based in San Francisco, California, the company employs artificial intelligence and machine learning algorithms to screen plant genes, identifying the most effective sources for addressing various health conditions. By uncovering naturally occurring compounds with potential health benefits, Brightseed aims to enhance the quality of life and support chronic disease management. The company’s mission is to strengthen the connection between people and plants, ultimately facilitating a healthier future for individuals and communities.

Abogen Biosciences

Series C in 2021
Abogen Biosciences is a discovery stage biotechnology company focuses on developing nucleic acid-based (RNA and DNA) therapeutics for treatment of cancer and infectious diseases.

Pivot Bio

Series D in 2021
Pivot Bio is a biotechnology company founded in 2010 and based in Emeryville, California, that focuses on enhancing crop nutrition through the use of engineered microbes. The company leverages its deep understanding of the plant microbiome, employing engineering principles and data science to map microbial dynamics and develop beneficial traits. Pivot Bio's proprietary ON Technology utilizes naturally occurring microbes to provide crops with essential nutrients, particularly nitrogen, which is crucial for growth. This innovative approach aims to replace synthetic nitrogen fertilizers, thereby reducing the environmental impact associated with conventional farming practices. By enhancing crops' ability to capture and metabolize atmospheric nitrogen, Pivot Bio seeks to lower farming costs, improve crop yields, and contribute to a sustainable agricultural future that benefits both the planet and food supply.

RecBio

Series C in 2021
Jiangsu Recbio Technology Co Ltd is a vaccine company dedicated to the development and commercialization of safer and more effective vaccines to address the far-unmet public needs. Hygiene needs. The company focuses on the R&D of HPV vaccine candidates. The company's vaccine portfolio currently consists of 12 vaccines, including three strategic products, namely REC603, a recombinant HPV 9-valent vaccine under phase III clinical trial.

Helix

Series C in 2021
Helix is a prominent population genomics company that operates at the intersection of clinical care, research, and data analytics. The company provides an end-to-end platform designed to facilitate genomic research and the incorporation of genomic data into healthcare practices. Helix operates one of the largest CLIA/CAP-certified next-generation sequencing laboratories and utilizes its proprietary Exome+™ assay to support various aspects of population genomics. These include recruitment and engagement, clinically actionable disease screening, and the return of results. Additionally, Helix engages in large-scale genetic analysis and viral surveillance, delivering actionable genetic insights that aid health systems, life sciences companies, payers, and government entities in enhancing patient care and informing public health decisions.

Clover Biopharmaceuticals

Series C in 2021
Clover Biopharmaceuticals is a clinical-stage biotechnology company based in Chengdu, China, focused on discovering and developing innovative biologic therapies for cancer, autoimmune diseases, and infectious diseases. Founded in 2007, the company utilizes its proprietary Trimer-Tag technology platform to create novel biologics that target trimerization-dependent pathways. Clover also offers integrated biopharmaceutical drug manufacturing services and has in-house capabilities for cGMP biomanufacturing, which support the development of select biosimilars. Through its research and development efforts, Clover aims to bring transformative therapies to the market.

Provivi

Series C in 2020
Provivi Inc. develops biopesticides for agriculture, commercial, household, and public health pest management. It develops research quantities of carbene/nitrene transferase enzymes that activate diazo and azide compounds to generate iron-carbenoids and iron-nitrenoids through a mode of activation. The company also develops a biocatalysis and fermentation technology, which is based on biocatalysts that enable efficient synthesis of biopesticides. Its technology has applications in industries, such as pharmaceuticals, nutrition, flavors, and fragrances. The company offers its products through distributors worldwide. Provivi Inc. was incorporated in 2012 and is based in Santa Monica, California.

Verily

Venture Round in 2020
Verily, founded in 2015 and based in San Francisco, California, focuses on integrating technology with life sciences to enhance health understanding and disease prevention. Formerly known as Google Life Sciences, the company aims to leverage advanced research tools and computing power to develop innovative healthcare solutions. Verily's multidisciplinary teams collaborate with various industry partners and researchers to create products such as glucose monitors, smart lenses, bioelectronic medicines, surgical robots, and precision medicines. These tools are designed to facilitate timely health data collection, enabling effective decision-making and interventions to predict and prevent disease onset and progression.

Locanabio

Series B in 2020
Locanabio, Inc. develops RNA-targeted gene therapies to treat a spectrum of underserved diseases. It offers therapies for neuromuscular, neurodegeneration, and ophthalmology diseases. Locanabio, Inc. was formerly known as Locana, Inc. and changed its name to Locanabio, Inc. in July 2020. The company was founded in 2016 and is based in San Diego, California.

D3 Bio

Series A in 2020
D3 Bio Inc. is a biotechnology company founded in 2020 and based in China. It specializes in the development and registration of innovative medicines, primarily focusing on oncology and immunology. The company adopts a unique approach to medicine development by first identifying significant unmet patient and market needs, particularly in areas where current treatments are inadequate. This understanding informs their research and guides the selection of appropriate scientific and technological methods to define their drug development strategy. Through this differentiated approach, D3 Bio aims to address critical health challenges and improve clinical outcomes for patients.

Tropic Biosciences

Series B in 2020
Tropic Biosciences UK LTD is a biotechnology company focused on developing high-performing commercial varieties of tropical crops, specifically targeting the coffee and banana industries. Established in 2016 and headquartered in Norwich, United Kingdom, the company employs advanced non-GMO gene editing technologies to enhance crop performance while promoting grower wellbeing and consumer health. Through its innovative approach, Tropic Biosciences aims to improve sustainable agricultural practices and address the challenges faced by tropical crop producers.

Ascus Biosciences

Series B in 2020
Ascus Biosciences, founded in 2015 and headquartered in San Diego, California, focuses on developing a computational and genomics-based technology platform aimed at discovering and creating next-generation microbial products. The company's innovative approach leverages advanced data analysis and genomic insights to enhance the development of microbial solutions, catering to various applications in biotechnology and related fields.

SQZ Biotech

Series D in 2020
SQZ Biotechnologies Company is a clinical-stage biotechnology firm based in Watertown, Massachusetts, focused on developing innovative cell therapies for cancer and other serious diseases. Its primary product candidate, SQZ-PBMC-HPV, is currently undergoing Phase I clinical trials as both a standalone treatment and in combination with other immuno-oncology agents for HPV16+ advanced or metastatic solid tumors. The company utilizes its proprietary CellSqueeze technology to deliver various materials into patient cells, aiming to engineer the immune system for both activation and suppression. Additionally, SQZ Biotech is advancing multiple platforms, including SQZ Activating Antigen Carriers and SQZ Tolerizing Antigen Carriers, to address diverse clinical challenges. Established in 2013, the company is dedicated to transforming cell therapies through internal research and strategic partnerships.

Pivot Bio

Series C in 2020
Pivot Bio is a biotechnology company founded in 2010 and based in Emeryville, California, that focuses on enhancing crop nutrition through the use of engineered microbes. The company leverages its deep understanding of the plant microbiome, employing engineering principles and data science to map microbial dynamics and develop beneficial traits. Pivot Bio's proprietary ON Technology utilizes naturally occurring microbes to provide crops with essential nutrients, particularly nitrogen, which is crucial for growth. This innovative approach aims to replace synthetic nitrogen fertilizers, thereby reducing the environmental impact associated with conventional farming practices. By enhancing crops' ability to capture and metabolize atmospheric nitrogen, Pivot Bio seeks to lower farming costs, improve crop yields, and contribute to a sustainable agricultural future that benefits both the planet and food supply.

Ceva Sante Animale

Venture Round in 2020
Ceva Sante Animale S.A. engages in the research, development, production, and marketing of pharmaceutical products and vaccines for companion and farm animals. They work with welfare and social programmes around the world to bring this vision to life – anywhere their products and know-how can make a difference and with all kinds of partners. From Uganda, working with small-scale livestock owners and vets to stop sleeping sickness in its tracks, to the UK and USA, where they supply the biggest animal welfare charities with Adaptil® collars to help re-home shelter dogs.

SQZ Biotech

Series D in 2019
SQZ Biotechnologies Company is a clinical-stage biotechnology firm based in Watertown, Massachusetts, focused on developing innovative cell therapies for cancer and other serious diseases. Its primary product candidate, SQZ-PBMC-HPV, is currently undergoing Phase I clinical trials as both a standalone treatment and in combination with other immuno-oncology agents for HPV16+ advanced or metastatic solid tumors. The company utilizes its proprietary CellSqueeze technology to deliver various materials into patient cells, aiming to engineer the immune system for both activation and suppression. Additionally, SQZ Biotech is advancing multiple platforms, including SQZ Activating Antigen Carriers and SQZ Tolerizing Antigen Carriers, to address diverse clinical challenges. Established in 2013, the company is dedicated to transforming cell therapies through internal research and strategic partnerships.

Provivi

Series C in 2019
Provivi Inc. develops biopesticides for agriculture, commercial, household, and public health pest management. It develops research quantities of carbene/nitrene transferase enzymes that activate diazo and azide compounds to generate iron-carbenoids and iron-nitrenoids through a mode of activation. The company also develops a biocatalysis and fermentation technology, which is based on biocatalysts that enable efficient synthesis of biopesticides. Its technology has applications in industries, such as pharmaceuticals, nutrition, flavors, and fragrances. The company offers its products through distributors worldwide. Provivi Inc. was incorporated in 2012 and is based in Santa Monica, California.

Viela Bio

Series B in 2019
Viela Bio, Inc. is a clinical-stage biotechnology company based in Gaithersburg, Maryland, focused on developing treatments for severe inflammation and autoimmune diseases. Its lead product candidate, inebilizumab, is a humanized monoclonal antibody targeting CD19, aimed at treating conditions such as neuromyelitis optica spectrum disorder, kidney transplant desensitization, myasthenia gravis, and IgG4-related diseases. The company is also advancing additional candidates, including VIB4920 for kidney transplantation rejection and Sjögren’s syndrome, as well as VIB7734 for cutaneous lupus erythematosus. Viela Bio has formed a strategic collaboration with Mitsubishi Tanabe Pharma Corporation to develop and commercialize inebilizumab for autoimmune diseases across several countries in Asia. Founded in 2017, the company is dedicated to addressing unmet medical needs in the field of autoimmune disorders.

Locanabio

Series A in 2019
Locanabio, Inc. develops RNA-targeted gene therapies to treat a spectrum of underserved diseases. It offers therapies for neuromuscular, neurodegeneration, and ophthalmology diseases. Locanabio, Inc. was formerly known as Locana, Inc. and changed its name to Locanabio, Inc. in July 2020. The company was founded in 2016 and is based in San Diego, California.

Genuity Science

Series C in 2018
Genuity Science is a contract genomics and data-sourcing organization based in Boston, Massachusetts, with additional offices in Dublin, Ireland, and Reykjavik, Iceland. The company collaborates with global biopharma firms to provide comprehensive discovery services that enhance precision health and improve patient outcomes. Its offerings encompass population-scale, disease-specific data sourcing, high-quality sequencing, and advanced statistical analysis, along with software tools for managing large datasets and artificial intelligence applications. Genuity operates state-of-the-art CAP/CLIA genomics laboratories in Woburn, Massachusetts, and Dublin, emphasizing a strong commitment to data stewardship and governance. The company focuses on exploring biological data insights, storage, interpretation, and scalable analytics, particularly in the central nervous system, cardiometabolic, and inflammatory disease sectors.

Pivot Bio

Series B in 2018
Pivot Bio is a biotechnology company founded in 2010 and based in Emeryville, California, that focuses on enhancing crop nutrition through the use of engineered microbes. The company leverages its deep understanding of the plant microbiome, employing engineering principles and data science to map microbial dynamics and develop beneficial traits. Pivot Bio's proprietary ON Technology utilizes naturally occurring microbes to provide crops with essential nutrients, particularly nitrogen, which is crucial for growth. This innovative approach aims to replace synthetic nitrogen fertilizers, thereby reducing the environmental impact associated with conventional farming practices. By enhancing crops' ability to capture and metabolize atmospheric nitrogen, Pivot Bio seeks to lower farming costs, improve crop yields, and contribute to a sustainable agricultural future that benefits both the planet and food supply.

Helix

Series B in 2018
Helix is a prominent population genomics company that operates at the intersection of clinical care, research, and data analytics. The company provides an end-to-end platform designed to facilitate genomic research and the incorporation of genomic data into healthcare practices. Helix operates one of the largest CLIA/CAP-certified next-generation sequencing laboratories and utilizes its proprietary Exome+™ assay to support various aspects of population genomics. These include recruitment and engagement, clinically actionable disease screening, and the return of results. Additionally, Helix engages in large-scale genetic analysis and viral surveillance, delivering actionable genetic insights that aid health systems, life sciences companies, payers, and government entities in enhancing patient care and informing public health decisions.

Viela Bio

Series A in 2018
Viela Bio, Inc. is a clinical-stage biotechnology company based in Gaithersburg, Maryland, focused on developing treatments for severe inflammation and autoimmune diseases. Its lead product candidate, inebilizumab, is a humanized monoclonal antibody targeting CD19, aimed at treating conditions such as neuromyelitis optica spectrum disorder, kidney transplant desensitization, myasthenia gravis, and IgG4-related diseases. The company is also advancing additional candidates, including VIB4920 for kidney transplantation rejection and Sjögren’s syndrome, as well as VIB7734 for cutaneous lupus erythematosus. Viela Bio has formed a strategic collaboration with Mitsubishi Tanabe Pharma Corporation to develop and commercialize inebilizumab for autoimmune diseases across several countries in Asia. Founded in 2017, the company is dedicated to addressing unmet medical needs in the field of autoimmune disorders.

Genuity Science

Series B in 2017
Genuity Science is a contract genomics and data-sourcing organization based in Boston, Massachusetts, with additional offices in Dublin, Ireland, and Reykjavik, Iceland. The company collaborates with global biopharma firms to provide comprehensive discovery services that enhance precision health and improve patient outcomes. Its offerings encompass population-scale, disease-specific data sourcing, high-quality sequencing, and advanced statistical analysis, along with software tools for managing large datasets and artificial intelligence applications. Genuity operates state-of-the-art CAP/CLIA genomics laboratories in Woburn, Massachusetts, and Dublin, emphasizing a strong commitment to data stewardship and governance. The company focuses on exploring biological data insights, storage, interpretation, and scalable analytics, particularly in the central nervous system, cardiometabolic, and inflammatory disease sectors.

Genuity Science

Series B in 2017
Genuity Science is a contract genomics and data-sourcing organization based in Boston, Massachusetts, with additional offices in Dublin, Ireland, and Reykjavik, Iceland. The company collaborates with global biopharma firms to provide comprehensive discovery services that enhance precision health and improve patient outcomes. Its offerings encompass population-scale, disease-specific data sourcing, high-quality sequencing, and advanced statistical analysis, along with software tools for managing large datasets and artificial intelligence applications. Genuity operates state-of-the-art CAP/CLIA genomics laboratories in Woburn, Massachusetts, and Dublin, emphasizing a strong commitment to data stewardship and governance. The company focuses on exploring biological data insights, storage, interpretation, and scalable analytics, particularly in the central nervous system, cardiometabolic, and inflammatory disease sectors.

Verily

Private Equity Round in 2017
Verily, founded in 2015 and based in San Francisco, California, focuses on integrating technology with life sciences to enhance health understanding and disease prevention. Formerly known as Google Life Sciences, the company aims to leverage advanced research tools and computing power to develop innovative healthcare solutions. Verily's multidisciplinary teams collaborate with various industry partners and researchers to create products such as glucose monitors, smart lenses, bioelectronic medicines, surgical robots, and precision medicines. These tools are designed to facilitate timely health data collection, enabling effective decision-making and interventions to predict and prevent disease onset and progression.

Visterra

Series B in 2014
Visterra, Inc. is a clinical-stage biopharmaceutical company focused on developing precision antibody-based treatments for difficult-to-treat diseases, particularly infectious diseases. Utilizing its Hierotope platform, Visterra designs monoclonal antibodies such as VIS410, aimed at treating hospitalized patients with influenza A, and VIS513 for Dengue fever. The company is also advancing VIS705, an antibody-drug conjugate for Pseudomonas aeruginosa infections, and VIS649, which targets Immunoglobulin A Nephropathy (IgAN). Founded in 2007 and based in Waltham, Massachusetts, Visterra was previously known as Parasol Therapeutics, Inc. The company operates as a subsidiary of Otsuka America, Inc. and emphasizes innovative therapeutic solutions to address significant unmet medical needs.

Ceva Sante Animale

Venture Round in 2014
Ceva Sante Animale S.A. engages in the research, development, production, and marketing of pharmaceutical products and vaccines for companion and farm animals. They work with welfare and social programmes around the world to bring this vision to life – anywhere their products and know-how can make a difference and with all kinds of partners. From Uganda, working with small-scale livestock owners and vets to stop sleeping sickness in its tracks, to the UK and USA, where they supply the biggest animal welfare charities with Adaptil® collars to help re-home shelter dogs.

Cyclacel Pharmaceuticals

Series D in 2004
Cyclacel Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on developing oral therapies for cancer and other proliferative diseases. Founded in 1996 by Professor Sir David Lane, a pioneer in tumor suppressor biology, the company specializes in targeting cell cycle control mechanisms. Its oncology programs include CYC065, a cyclin-dependent kinase inhibitor currently in Phase I trials for solid tumors and chronic lymphocytic leukemia, and CYC140, a polo-like kinase inhibitor also in Phase I trials for advanced leukemias. Additionally, Cyclacel is advancing sapacitabine, an oral nucleoside analogue, through multiple studies, including a Phase III trial for acute myeloid leukemia and combination studies with other agents for patients with BRCA mutations. The company collaborates with the University of Texas MD Anderson Cancer Center to evaluate the safety and efficacy of its drugs in hematological malignancies, and has a partnership with ManRos Therapeutics for the development of oral seliciclib capsules for cystic fibrosis. Cyclacel is headquartered in Berkeley Heights, New Jersey.

BioVex

Series C in 2003
BioVex is a biotechnology company focused on the development and commercialization of biological treatments for cancer and the prevention of infectious disease. Their cancer program, OncoVEXGM-CSF, is a oncolytic vaccine or cancer destroying virus technology that works by replicating and spreading within solid tumors, causing the death of cancer cells while leaving surrounding healthy cells unharmed. The attenuated virus has also been constructed to induce a powerful systemic anti tumor immune response. OncoVEXGM-CSF has now been tested in >110 patients in a broad range of solid tumors including melanoma, head & neck cancer, breast cancer and pancreatic cancer. Both the direct cell killing and systemic immune mediated mechanisms of action of OncoVEX have been clearly validated in the clinic; OncoVEX routinely destroys tumors it is directly injected into and has led to overall disease responses in multiple patients in Phase II testing. Tumors resolved through OncoVEX treatment have not been known to recur.
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