Khosla Impact

Khosla Impact, established in 2013, is an impact investment firm based in Menlo Park, California. It focuses on assisting high-impact entrepreneurs who develop products and services for the three billion people at the bottom of the world's economic pyramid. The firm invests in for-profit enterprises serving low-income individuals and small businesses in emerging markets, with a primary focus on South Asia. Khosla Impact encourages experimentation and supports entrepreneurs passionate about solving socio-economic challenges through technology and innovative business models.

Alex Bentley

Partner and Investor

Ryno Blignaut

Operating Partner

Alice Brooks

Partner and Investor

Peter Buckland

COO, Partner, and Managing Director

Brian Byun

Operating Partner

Catherine Casuga

Operating Partner

Jonathan Chu

Partner and Investor

Ardy Daie

Operating Partner

Ece Erdagoz Wyrick

Principal and Investor

Kanu Gulati

Partner

Judy Huang

Operating Partner

Jun Jeon MD

Principal

Samir Kaul

Founding Partner and Managing Director

Vinod Khosla

Managing Director

Kelly Kinnard

Operating Partner

Nicholas Moryl

Associate

Keith Rabois

Managing Director

Arash Rebek

Partner, Capital Formation

Jessy Rivest

Partner and Investor

Jai Sajnani

Partner and Investor

Jai Sajnani

Partner

Leah Scanlan

Operating Partner

Nikita Shamgunov

Partner and Investor

Sven Strohband

Managing Director

Rajesh Swaminathan

Partner and Investor

Adina Tecklu

Partner and Investor

David Weiden

Managing Director

Reze Wong

Partner

Kanupriya Gulati Ph.D

Partner and Investor

Adam Coates

Operating Partner

Past deals in Life Science

Viome Life Sciences

Series D in 2024
Viome Life Sciences, established in 2016 and headquartered in Bellevue, Washington, specializes in providing comprehensive health insights through its proprietary at-home clinical-grade tests. The company analyzes RNA from stool samples, along with other bodily fluids, to determine the makeup of microbial communities, offering personalized recommendations for diet and lifestyle based on the results. Viome's services aim to empower individuals to track their microbiome health, mitochondrial health, cellular health, and biological age, ultimately aiding in the prevention and reversal of chronic diseases. The company operates as a subsidiary of BlueDot LLC and sells its products through distributors and online channels.

Karius

Series C in 2024
Karius, Inc. is a life sciences company based in Redwood City, California, with an additional office in Menlo Park. Founded in 2014, Karius specializes in generating genomic insights for infectious diseases through its innovative Karius Test. This non-invasive blood test utilizes sequencing of microbial cell-free DNA to identify and quantify a wide range of pathogens, including bacteria, DNA viruses, fungi, and parasites. The Karius Test is particularly useful in the diagnosis of complicated pneumonia, infections in immunocompromised patients, and endocarditis, enabling clinicians to make rapid and informed treatment decisions. Karius operates a CLIA-certified and CAP-accredited laboratory, providing high-complexity clinical laboratory testing and offering services for pathogen biomarker detection aimed at biopharmaceutical companies. The company is dedicated to advancing the understanding and management of infectious diseases, striving for a future where these conditions pose less of a threat to human health.

Rubedo Life Sciences

Series A in 2024
Rubedo Life Sciences, Inc. is a biopharmaceutical company based in Sunnyvale, California, focused on developing innovative therapies that target senescent cells implicated in age-related diseases. Established in 2018, the company utilizes its proprietary ALEMBIC drug discovery platform to create a pipeline of therapeutic candidates. These candidates are designed to selectively address senescent cells, as well as pro-inflammatory and pro-fibrotic cell populations that contribute to various chronic conditions, including pulmonary, dermatological, oncological, neurodegenerative, and fibrotic diseases. Rubedo's leadership team comprises industry experts with significant experience in drug development and commercialization across both large pharmaceutical companies and biotech firms.

Nabla Bio

Series A in 2024
Nabla Bio is a biotechnology company that specializes in the development of an autoreverse platform for the discovery of innovative protein variants. These proteins, which exhibit unique qualities, are engineered to create new medicines and enhance nutritional products. By leveraging insights gained from billions of natural proteins, Nabla Bio enhances these variants through extensive experimentation, allowing for advanced applications in both medical and industrial fields. The company's focus on complex measurements of protein function positions it as a leader in the pursuit of previously unattainable protein capabilities.

Loyal

Series B in 2024
Loyal is a biotechnology company focused on developing veterinary pharmaceuticals aimed at extending the health span and lifespan of dogs. The company creates medicines designed to delay the onset of age-related diseases such as cancer, heart disease, and metabolic disorders. By quantifying and regulating the aging process, Loyal seeks to mitigate the effects of aging, thereby promoting healthier and longer lives for dogs. Through its innovative approach, the company aspires to improve the quality of life for pets and enhance their longevity.

Relation Therapeutics

Seed Round in 2024
Relation Therapeutics is a biotechnology company focused on advancing drug discovery and development. It utilizes human genetics and clinical omics data, alongside patient-derived tissue samples, to identify and validate therapeutic programs. The company employs machine learning to explore the relationships between genes, proteins, and drugs, generating insights that have real translational validity. By combining single-cell multi-omics from patient tissues with functional assays, Relation Therapeutics aims to deepen the understanding of biological processes in human health and disease. This approach enables healthcare providers to discover and develop novel treatments, particularly in areas with unmet medical needs.

Siolta Therapeutics

Series C in 2024
Siolta Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing microbiome-based therapeutics and diagnostics aimed at preventing and treating chronic inflammatory diseases, particularly asthma and atopic conditions. Founded in 2016 and headquartered in San Francisco, California, the company utilizes its extensive understanding of the developing gut microbiome to promote immune tolerance. Siolta Therapeutics is advancing pharmaceutical-grade anaerobic organisms and is currently in phase 2 of development for its products. By leveraging insights from human microbiome studies, the company aims to create targeted microbial therapeutics and companion diagnostics that facilitate precision medicine in the management of inflammatory diseases.

Moonwalk Biosciences

Series A in 2024
Moonwalk Biosciences is a genomic medicine startup focused on developing precision epigenetic therapeutics. The company specializes in creating a profiling and engineering technology platform that leverages advanced artificial intelligence predictions to offer a comprehensive view of the epigenome in both health and disease states. This innovative approach aims to revolutionize therapy discovery and development, enabling healthcare providers to reprogram cells back to their healthy state.

Encellin

Series A in 2023
Encellin Inc., established in 2016, is a biotechnology company based in San Francisco, California. It specializes in developing innovative thin-film cell encapsulation devices for cell-based therapeutics, aiming to improve the lives of patients with chronic diseases initially focusing on Type 1 diabetes. The company's technology enables encapsulated cells to function as smart molecular factories, providing potential therapeutic solutions.

Eligo Bioscience

Series B in 2023
Eligo Bioscience S.A.S is a biotechnology company founded in 2014 and based in Paris, France, specializing in the development of Eligobiotics, a novel class of antimicrobials. These therapeutics are designed to target specific bacteria based on their genomic information, utilizing a combination of CRISPR/Cas technology and engineered phage capsids. This advanced approach allows Eligo to create precision antibiotics aimed at eradicating resistant pathogens and virulent bacteria within the human microbiome. The applications of Eligobiotics extend beyond pharmaceuticals; they also encompass areas such as cosmetics and biodefense, addressing a variety of bacteria-associated diseases and offering next-generation solutions to combat superbugs.

Vivodyne

Seed Round in 2023
Vivodyne is a biotechnology company that specializes in developing an advanced automated robotic system aimed at discovering innovative drugs and cellular therapies. The company has created a microfluidic bioengineering platform that focuses on single-cell 4D phenomics, allowing for a detailed exploration of biological complexities. Its technology enables the cultivation of highly realistic human tissue models for drug discovery, incorporating an integrated confocal microscope. This platform not only accelerates the drug development process but also allows researchers to formulate tunable mixtures of compounds and cell therapies. Through its unique approach, Vivodyne seeks to advance the understanding of human health and facilitate the creation of effective treatments for various diseases.

CellFE

Series A in 2023
CellFE Inc. is a biotechnology company based in San Carlos, California, established in 2017. It specializes in the development of a microfluidics-based device designed to deliver gene-editing molecules into human cells. This innovative platform enhances the manufacturing and development of cell therapies by utilizing rapid cell compression techniques that facilitate the uptake of therapeutic molecules from surrounding fluids. By enabling the transport of hard-to-deliver molecules, CellFE aims to improve the effectiveness of treatments for various disorders, supporting medical researchers in their efforts to advance patient care and outcomes.

Rejuvenation Technologies

Seed Round in 2023
Rejuvenation Technologies Inc., established in 2016 and based in Mountain View, California, is a biotechnology company specializing in developing nucleoside-modified TERT mRNA. This technology safely and rapidly extends telomeres, enabling cells to proliferate more effectively. The company focuses on regenerative medicine applications, aiming to target age-related diseases and conditions across various organs such as the liver, lungs, and immune system. Their offerings include cell therapies like tissue engineering, transplants, skin grafts, immunotherapy, and regeneration medicine.

Viome Life Sciences

Series C in 2023
Viome Life Sciences, established in 2016 and headquartered in Bellevue, Washington, specializes in providing comprehensive health insights through its proprietary at-home clinical-grade tests. The company analyzes RNA from stool samples, along with other bodily fluids, to determine the makeup of microbial communities, offering personalized recommendations for diet and lifestyle based on the results. Viome's services aim to empower individuals to track their microbiome health, mitochondrial health, cellular health, and biological age, ultimately aiding in the prevention and reversal of chronic diseases. The company operates as a subsidiary of BlueDot LLC and sells its products through distributors and online channels.

SiPhox Health

Seed Round in 2023
SiPhox Health, based in Cambridge, Massachusetts, specializes in designing and manufacturing innovative diagnostic solutions. The company develops next-generation diagnostics infrastructure, including at-home test kits and central lab systems. Their flagship product is a disposable biosensor cartridge that assesses 17 blood biomarkers, providing insights into inflammation, hormonal health, metabolic fitness, and cardiovascular health. SiPhox Health's platform merges biochemistry, photonic chip technology, integrated photonics, electronics, and microfluidics to enable sensitive readouts of immunoassays and nucleic acid tests, facilitating point-of-need and at-home diagnostics.

Surge Therapeutics

Series B in 2023
SURGE Therapeutics is a biotechnology company focused on enhancing cancer treatment outcomes through innovative immunotherapy solutions. It has developed a proprietary injectable biodegradable hydrogel designed to deliver cancer therapeutics in a prolonged and localized manner. This technology enables targeted release of immunotherapy agents at the surgical site following tumor resection, allowing for more effective treatment administration. By optimizing the timing and location of drug delivery, SURGE Therapeutics aims to improve patient survival rates and minimize systemic side effects, representing a significant advancement in the field of cancer care.

SiPhox Health

Series A in 2023
SiPhox Health, based in Cambridge, Massachusetts, specializes in designing and manufacturing innovative diagnostic solutions. The company develops next-generation diagnostics infrastructure, including at-home test kits and central lab systems. Their flagship product is a disposable biosensor cartridge that assesses 17 blood biomarkers, providing insights into inflammation, hormonal health, metabolic fitness, and cardiovascular health. SiPhox Health's platform merges biochemistry, photonic chip technology, integrated photonics, electronics, and microfluidics to enable sensitive readouts of immunoassays and nucleic acid tests, facilitating point-of-need and at-home diagnostics.

Tachyon

Series A in 2023
Tachyon Therapeutics is a biotechnology company focused on research and development aimed at creating innovative therapeutics for cancer treatment. The company is dedicated to developing first-in-class compounds that target new drug mechanisms in cancer biology, employing advanced techniques in molecular cancer biology, epigenetics, and cancer stem cell research. Currently, Tachyon is conducting Phase 1 clinical trials to evaluate the safety, pharmacokinetics, and anti-tumor effectiveness of its lead candidate, TACH101, in patients with advanced cancer. Through a commitment to high-quality and scientifically sound practices, Tachyon aims to provide novel treatment options that unlock new pathways for addressing complex cancer cases.

Surge Therapeutics

Series A in 2022
SURGE Therapeutics is a biotechnology company focused on enhancing cancer treatment outcomes through innovative immunotherapy solutions. It has developed a proprietary injectable biodegradable hydrogel designed to deliver cancer therapeutics in a prolonged and localized manner. This technology enables targeted release of immunotherapy agents at the surgical site following tumor resection, allowing for more effective treatment administration. By optimizing the timing and location of drug delivery, SURGE Therapeutics aims to improve patient survival rates and minimize systemic side effects, representing a significant advancement in the field of cancer care.

Viome Life Sciences

Series C in 2022
Viome Life Sciences, established in 2016 and headquartered in Bellevue, Washington, specializes in providing comprehensive health insights through its proprietary at-home clinical-grade tests. The company analyzes RNA from stool samples, along with other bodily fluids, to determine the makeup of microbial communities, offering personalized recommendations for diet and lifestyle based on the results. Viome's services aim to empower individuals to track their microbiome health, mitochondrial health, cellular health, and biological age, ultimately aiding in the prevention and reversal of chronic diseases. The company operates as a subsidiary of BlueDot LLC and sells its products through distributors and online channels.

Ochre Bio

Series A in 2022
Ochre Bio Ltd is a biotechnology company focused on developing genomic medicines specifically for transplanted livers and the treatment of fatty liver conditions. Founded in 2019 and based in Headington, United Kingdom, the company employs advanced genomic techniques to identify and inhibit overactive genes associated with liver diseases. This approach includes testing therapies in discarded donor livers that are maintained outside the body, ensuring that potential treatments can be evaluated in a relevant biological context. With over 15 years of expertise in liver genomics research, Ochre Bio aims to create a pipeline of innovative medicines that address liver and liver-mediated conditions, ultimately enhancing the availability of healthy livers for transplantation and reducing complications associated with cirrhosis. The company operates within Oxford's biotechnology innovation hub, leveraging its scientific foundation to advance therapeutic solutions in the field of liver health.

Prellis Biologics

Series C in 2022
Prellis Biologics, Inc. is a biotechnology company based in San Francisco, California, that specializes in bioprinting human tissues for drug development and organ transplantation. Founded in 2016, the company focuses on overcoming the challenges of creating vascularized human tissues and organs, aiming to revolutionize healthcare. Its innovative technology allows for the precise engineering of human tissues, including lymph node organoids, which can replicate human immune responses for various applications such as antibody discovery and tumor-immune modeling. Prellis Biologics offers a range of products, including TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X, which collectively enhance early-stage drug discovery and translational pharmacology.

Genecis

Series A in 2022
Genecis is an early-stage organic waste processing startup that uses biotechnology to convert waste into biodegradable plastics and other high-value materials. It converts organic waste into PHA (Polyhydroxyalkanoate), a biodegradable, compostable, and non-toxic polymer that can be tuned to replace a wide variety of traditional plastics. PHA can be used for single-use plastics, clothing and textiles, automotive interiors, medical tools and products, and food contact applications.

Faeth Therapeutics

Series A in 2022
Faeth Therapeutics is a healthcare company dedicated to enhancing cancer treatment through a deep understanding of the relationship between dietary nutrients and tumor growth. By aligning specific diets with tumor genotypes and treatment regimens, Faeth aims to limit the energy and resources that tumors need to proliferate, thereby improving patient outcomes in cancer therapy. Founded by leading researchers and clinicians, the company seeks to translate significant discoveries from cancer research laboratories into effective clinical practices, focusing on evidence-based approaches to optimize treatment strategies for cancer patients.

Relation Therapeutics

Seed Round in 2022
Relation Therapeutics is a biotechnology company focused on advancing drug discovery and development. It utilizes human genetics and clinical omics data, alongside patient-derived tissue samples, to identify and validate therapeutic programs. The company employs machine learning to explore the relationships between genes, proteins, and drugs, generating insights that have real translational validity. By combining single-cell multi-omics from patient tissues with functional assays, Relation Therapeutics aims to deepen the understanding of biological processes in human health and disease. This approach enables healthcare providers to discover and develop novel treatments, particularly in areas with unmet medical needs.

Anagenex

Series A in 2022
Anagenex is a seed stage biotechnology company that specializes in drug discovery, focusing on challenging medical targets. The company has developed an innovative platform that significantly accelerates the discovery of small molecule drugs and the identification of pharmaceutical compounds. By utilizing machine learning in conjunction with DNA-encoded libraries, Anagenex's technology can rapidly analyze a vast number of compounds, generating extensive data sets and conducting parallel biochemical experiments. This capability is enhanced by proprietary artificial intelligence models, which facilitate the development of new therapeutic drugs aimed at addressing critical medical needs.

Ultima Genomics

Venture Round in 2022
Ultima Genomics is a biotechnology company established in 2016 and headquartered in Newark, California. It specializes in genome-scale sequencing technology, focusing on providing analytical services to various enterprises. By employing an open substrate, Ultima Genomics creates a vast, low-cost reaction surface that facilitates billions of reads without relying on expensive flow cells or complex fluidic systems. The company utilizes specialized sequencing hardware combined with machine learning techniques to ensure reproducible and accurate results. This innovative approach enables clients to obtain genomic reports at scale, enhancing the speed and efficiency of sequencing while significantly reducing costs. Ultima Genomics aims to harness the potential of genomic information to drive advancements in biology and improve human health.

VitroLabs

Series A in 2022
VitroLabs, Inc. is a San Jose, California-based startup specializing in 3D tissue engineering and biomaterials. Founded in 2016, the company focuses on developing innovative, scalable solutions for creating authentic leather and other luxury materials through advanced stem cell technologies. By leveraging breakthroughs in tissue engineering, VitroLabs produces lab-grown leather that eliminates the need for animal raising and slaughter, promoting sustainability in the fashion and interior design industries. Its unique approach allows fashion brands to manufacture high-quality products while adhering to ethical practices.

turn.bio

Venture Round in 2022
Turn.bio is a biotechnology company focused on developing innovative therapies aimed at reversing aging and age-related diseases. Leveraging a patented mRNA platform technology known as ERA, along with a specialized delivery system called eTurna, the company targets the epigenome to restore optimal gene expression. By designing tailored therapies, Turn.bio addresses a range of conditions, including immune-related diseases such as cancer, dermatological issues, and ailments in ophthalmology, osteoarthritis, and the muscular system. The company's approach involves inducing the body to heal itself by instructing specific cells to combat disease and repair damaged tissue, thereby reprogramming cellular functions to enhance health and longevity.

Volta Labs

Series A in 2022
Volta Labs, Inc. is a biotechnology company based in Cambridge, Massachusetts, founded in 2018. The company specializes in engineering and developing innovative tools for biological automation, focusing on scalable automation solutions for genetic engineering. Its platform is designed to revolutionize genomics research by providing affordable genomic sample preparation and automation for complex biological workflows. By integrating expertise from engineering, surface chemistry, and molecular biology, Volta Labs aims to streamline sample processing and enhance the capabilities of biotech organizations in the next generation of genomic automation.

Scipher Medicine

Series D in 2022
Scipher Medicine Corporation is a biotechnology company based in Waltham, Massachusetts, that specializes in precision medicine for patients with autoimmune and cardiovascular diseases. The company has developed a molecular technology platform that utilizes blood samples to analyze RNA and predict patient responses to drug therapies. Its primary offerings include PrismDx tests, which identify patients who may not respond to certain medications, ensuring they can be prescribed alternative treatments. Notably, the PrismRA test assesses patients with rheumatoid arthritis to determine their likelihood of responding to anti-TNF therapies, while PrismUC serves a similar purpose for patients with ulcerative colitis. By focusing on the underlying disease biology rather than just symptoms, Scipher Medicine aims to optimize treatment from the outset, potentially reducing the healthcare costs associated with ineffective therapies. Established in 2013 and rebranded in 2015, Scipher Medicine is committed to transforming drug prescription practices and advancing drug development through its innovative approach.

Cellino

Series A in 2022
Cellino is focused on developing a scalable, automated biomanufacturing system aimed at producing personalized cell therapies. The company's innovative platform leverages AI-guided laser editing to generate autologous induced pluripotent stem cells (iPSCs) efficiently and at scale. By utilizing image-guided machine learning, single-cell laser processing, and robotics, Cellino seeks to make advanced, potentially curative treatments accessible for a range of chronic degenerative diseases, including vision loss and Parkinson's disease. The company's mission is to transform healthcare by enabling personalized therapies that can significantly improve patient outcomes and overall health.

Faeth Therapeutics

Seed Round in 2022
Faeth Therapeutics is a healthcare company dedicated to enhancing cancer treatment through a deep understanding of the relationship between dietary nutrients and tumor growth. By aligning specific diets with tumor genotypes and treatment regimens, Faeth aims to limit the energy and resources that tumors need to proliferate, thereby improving patient outcomes in cancer therapy. Founded by leading researchers and clinicians, the company seeks to translate significant discoveries from cancer research laboratories into effective clinical practices, focusing on evidence-based approaches to optimize treatment strategies for cancer patients.

Anagenex

Seed Round in 2022
Anagenex is a seed stage biotechnology company that specializes in drug discovery, focusing on challenging medical targets. The company has developed an innovative platform that significantly accelerates the discovery of small molecule drugs and the identification of pharmaceutical compounds. By utilizing machine learning in conjunction with DNA-encoded libraries, Anagenex's technology can rapidly analyze a vast number of compounds, generating extensive data sets and conducting parallel biochemical experiments. This capability is enhanced by proprietary artificial intelligence models, which facilitate the development of new therapeutic drugs aimed at addressing critical medical needs.

Prellis Biologics

Series B in 2021
Prellis Biologics, Inc. is a biotechnology company based in San Francisco, California, that specializes in bioprinting human tissues for drug development and organ transplantation. Founded in 2016, the company focuses on overcoming the challenges of creating vascularized human tissues and organs, aiming to revolutionize healthcare. Its innovative technology allows for the precise engineering of human tissues, including lymph node organoids, which can replicate human immune responses for various applications such as antibody discovery and tumor-immune modeling. Prellis Biologics offers a range of products, including TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X, which collectively enhance early-stage drug discovery and translational pharmacology.

NextVivo

Seed Round in 2021
NextVivo is a biotech company focused on advancing drug development through its innovative immune organoid technology platform. The company aims to create safer and more effective therapies by utilizing immune-competent, human-derived models. Its technology involves the use of miniature 3D cell cultures, known as organoids, which accurately replicate the composition, structure, and function of human tissue. This unique approach allows for the modeling of both humoral and cellular immune responses outside the human body. By enabling the testing of pre-clinical candidates on ex vivo human tissue models, NextVivo facilitates the identification of the most promising therapies for clinical development, thereby enhancing the drug discovery process.

Nabla Bio

Seed Round in 2021
Nabla Bio is a biotechnology company that specializes in the development of an autoreverse platform for the discovery of innovative protein variants. These proteins, which exhibit unique qualities, are engineered to create new medicines and enhance nutritional products. By leveraging insights gained from billions of natural proteins, Nabla Bio enhances these variants through extensive experimentation, allowing for advanced applications in both medical and industrial fields. The company's focus on complex measurements of protein function positions it as a leader in the pursuit of previously unattainable protein capabilities.

Fountain Therapeutics

Series A in 2021
Fountain Therapeutics, established in 2018 and headquartered in San Francisco, specializes in developing treatments for age-related diseases using cellular models and an AI-based platform for target discovery. The company aims to recreate aging's complex hallmarks in lab dishes, combining this model with artificial intelligence and computer vision to identify novel targets unbiasedly.

Viome Life Sciences

Series C in 2021
Viome Life Sciences, established in 2016 and headquartered in Bellevue, Washington, specializes in providing comprehensive health insights through its proprietary at-home clinical-grade tests. The company analyzes RNA from stool samples, along with other bodily fluids, to determine the makeup of microbial communities, offering personalized recommendations for diet and lifestyle based on the results. Viome's services aim to empower individuals to track their microbiome health, mitochondrial health, cellular health, and biological age, ultimately aiding in the prevention and reversal of chronic diseases. The company operates as a subsidiary of BlueDot LLC and sells its products through distributors and online channels.

Pearl Bio

Seed Round in 2021
Pearl Bio is a synthetic biology company focused on innovating biologics and biomaterials through advanced technologies. It has developed a platform that encompasses genome engineering, ribosome engineering, and biomanufacturing. This platform enables the creation of smart biologics and biomaterials, allowing scientists to enhance their understanding of gene function. By employing these techniques, Pearl Bio aims to facilitate the development of products, tools, and processes that can be scaled for commercial use, ultimately contributing to the treatment of genetic and acquired diseases.

Lightship

Series C in 2021
Lightship is a company founded in 2018 that focuses on transforming clinical trials to enhance health equity globally. By leveraging digital health innovations and remote care, it aims to make clinical research more accessible and patient-centered. Lightship provides decentralized and hybrid clinical services that improve patient experience, retention, and trial diversity. Its approach expands the pool of potential participants by moving beyond traditional research centers, effectively meeting patients in their own environments. This strategy helps to eliminate the barriers and inefficiencies associated with conventional clinical trial models, ultimately making medical research more inclusive and effective.

VitroLabs

Series A in 2021
VitroLabs, Inc. is a San Jose, California-based startup specializing in 3D tissue engineering and biomaterials. Founded in 2016, the company focuses on developing innovative, scalable solutions for creating authentic leather and other luxury materials through advanced stem cell technologies. By leveraging breakthroughs in tissue engineering, VitroLabs produces lab-grown leather that eliminates the need for animal raising and slaughter, promoting sustainability in the fashion and interior design industries. Its unique approach allows fashion brands to manufacture high-quality products while adhering to ethical practices.

Loyal

Series A in 2021
Loyal is a biotechnology company focused on developing veterinary pharmaceuticals aimed at extending the health span and lifespan of dogs. The company creates medicines designed to delay the onset of age-related diseases such as cancer, heart disease, and metabolic disorders. By quantifying and regulating the aging process, Loyal seeks to mitigate the effects of aging, thereby promoting healthier and longer lives for dogs. Through its innovative approach, the company aspires to improve the quality of life for pets and enhance their longevity.

Encellin

Seed Round in 2021
Encellin Inc., established in 2016, is a biotechnology company based in San Francisco, California. It specializes in developing innovative thin-film cell encapsulation devices for cell-based therapeutics, aiming to improve the lives of patients with chronic diseases initially focusing on Type 1 diabetes. The company's technology enables encapsulated cells to function as smart molecular factories, providing potential therapeutic solutions.

Deep Genomics

Series C in 2021
Deep Genomics Inc. is an artificial intelligence therapeutics company based in Toronto, Canada, founded in 2014. The company focuses on developing individualized genetic medicines by utilizing AI systems to enhance various aspects of drug discovery and development, such as target discovery, lead optimization, toxicity assessment, and innovative trial design. Deep Genomics specializes in creating oligonucleotide therapies that address the genetic underpinnings of diseases at the RNA and DNA levels, targeting rare metabolic, ophthalmologic, and neurodegenerative disorders. Its AI-powered platform decodes the complexities of RNA biology, enabling the identification of novel therapeutic targets and mechanisms that traditional methods cannot access. This innovative approach positions Deep Genomics at the forefront of revolutionizing drug discovery, ultimately aiming to provide new treatments for currently untreatable diseases.

Ochre Bio

Seed Round in 2021
Ochre Bio Ltd is a biotechnology company focused on developing genomic medicines specifically for transplanted livers and the treatment of fatty liver conditions. Founded in 2019 and based in Headington, United Kingdom, the company employs advanced genomic techniques to identify and inhibit overactive genes associated with liver diseases. This approach includes testing therapies in discarded donor livers that are maintained outside the body, ensuring that potential treatments can be evaluated in a relevant biological context. With over 15 years of expertise in liver genomics research, Ochre Bio aims to create a pipeline of innovative medicines that address liver and liver-mediated conditions, ultimately enhancing the availability of healthy livers for transplantation and reducing complications associated with cirrhosis. The company operates within Oxford's biotechnology innovation hub, leveraging its scientific foundation to advance therapeutic solutions in the field of liver health.

turn.bio

Funding Round in 2021
Turn.bio is a biotechnology company focused on developing innovative therapies aimed at reversing aging and age-related diseases. Leveraging a patented mRNA platform technology known as ERA, along with a specialized delivery system called eTurna, the company targets the epigenome to restore optimal gene expression. By designing tailored therapies, Turn.bio addresses a range of conditions, including immune-related diseases such as cancer, dermatological issues, and ailments in ophthalmology, osteoarthritis, and the muscular system. The company's approach involves inducing the body to heal itself by instructing specific cells to combat disease and repair damaged tissue, thereby reprogramming cellular functions to enhance health and longevity.

Scipher Medicine

Series C in 2021
Scipher Medicine Corporation is a biotechnology company based in Waltham, Massachusetts, that specializes in precision medicine for patients with autoimmune and cardiovascular diseases. The company has developed a molecular technology platform that utilizes blood samples to analyze RNA and predict patient responses to drug therapies. Its primary offerings include PrismDx tests, which identify patients who may not respond to certain medications, ensuring they can be prescribed alternative treatments. Notably, the PrismRA test assesses patients with rheumatoid arthritis to determine their likelihood of responding to anti-TNF therapies, while PrismUC serves a similar purpose for patients with ulcerative colitis. By focusing on the underlying disease biology rather than just symptoms, Scipher Medicine aims to optimize treatment from the outset, potentially reducing the healthcare costs associated with ineffective therapies. Established in 2013 and rebranded in 2015, Scipher Medicine is committed to transforming drug prescription practices and advancing drug development through its innovative approach.

Cellino

Seed Round in 2021
Cellino is focused on developing a scalable, automated biomanufacturing system aimed at producing personalized cell therapies. The company's innovative platform leverages AI-guided laser editing to generate autologous induced pluripotent stem cells (iPSCs) efficiently and at scale. By utilizing image-guided machine learning, single-cell laser processing, and robotics, Cellino seeks to make advanced, potentially curative treatments accessible for a range of chronic degenerative diseases, including vision loss and Parkinson's disease. The company's mission is to transform healthcare by enabling personalized therapies that can significantly improve patient outcomes and overall health.

Rubedo Life Sciences

Seed Round in 2020
Rubedo Life Sciences, Inc. is a biopharmaceutical company based in Sunnyvale, California, focused on developing innovative therapies that target senescent cells implicated in age-related diseases. Established in 2018, the company utilizes its proprietary ALEMBIC drug discovery platform to create a pipeline of therapeutic candidates. These candidates are designed to selectively address senescent cells, as well as pro-inflammatory and pro-fibrotic cell populations that contribute to various chronic conditions, including pulmonary, dermatological, oncological, neurodegenerative, and fibrotic diseases. Rubedo's leadership team comprises industry experts with significant experience in drug development and commercialization across both large pharmaceutical companies and biotech firms.

Siolta Therapeutics

Series B in 2020
Siolta Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing microbiome-based therapeutics and diagnostics aimed at preventing and treating chronic inflammatory diseases, particularly asthma and atopic conditions. Founded in 2016 and headquartered in San Francisco, California, the company utilizes its extensive understanding of the developing gut microbiome to promote immune tolerance. Siolta Therapeutics is advancing pharmaceutical-grade anaerobic organisms and is currently in phase 2 of development for its products. By leveraging insights from human microbiome studies, the company aims to create targeted microbial therapeutics and companion diagnostics that facilitate precision medicine in the management of inflammatory diseases.

SiPhox Health

Seed Round in 2020
SiPhox Health, based in Cambridge, Massachusetts, specializes in designing and manufacturing innovative diagnostic solutions. The company develops next-generation diagnostics infrastructure, including at-home test kits and central lab systems. Their flagship product is a disposable biosensor cartridge that assesses 17 blood biomarkers, providing insights into inflammation, hormonal health, metabolic fitness, and cardiovascular health. SiPhox Health's platform merges biochemistry, photonic chip technology, integrated photonics, electronics, and microfluidics to enable sensitive readouts of immunoassays and nucleic acid tests, facilitating point-of-need and at-home diagnostics.

Genalyte

Series C in 2020
Genalyte, Inc. is a clinical and diagnostic life sciences company based in San Diego, California, that specializes in rapid diagnostic testing solutions for healthcare providers, patients, and researchers. Founded in 2007, Genalyte has developed a unique technology platform employing silicon photonic biosensors to quantify the interactions between biomolecules, such as antibodies and proteins. This innovative approach allows for the direct measurement of protein binding and nucleic acid hybridization, facilitating the monitoring of autoimmune diseases, cancer biomarker screening, and the detection of infectious agents, including Ebola. The company's Maverick platform enables rapid testing in various healthcare settings, with results typically available in under thirty minutes, thereby enhancing patient care and improving resource efficiency within the healthcare system.

Karius

Series B in 2020
Karius, Inc. is a life sciences company based in Redwood City, California, with an additional office in Menlo Park. Founded in 2014, Karius specializes in generating genomic insights for infectious diseases through its innovative Karius Test. This non-invasive blood test utilizes sequencing of microbial cell-free DNA to identify and quantify a wide range of pathogens, including bacteria, DNA viruses, fungi, and parasites. The Karius Test is particularly useful in the diagnosis of complicated pneumonia, infections in immunocompromised patients, and endocarditis, enabling clinicians to make rapid and informed treatment decisions. Karius operates a CLIA-certified and CAP-accredited laboratory, providing high-complexity clinical laboratory testing and offering services for pathogen biomarker detection aimed at biopharmaceutical companies. The company is dedicated to advancing the understanding and management of infectious diseases, striving for a future where these conditions pose less of a threat to human health.

Fountain Therapeutics

Series A in 2020
Fountain Therapeutics, established in 2018 and headquartered in San Francisco, specializes in developing treatments for age-related diseases using cellular models and an AI-based platform for target discovery. The company aims to recreate aging's complex hallmarks in lab dishes, combining this model with artificial intelligence and computer vision to identify novel targets unbiasedly.

Lightship

Series B in 2020
Lightship is a company founded in 2018 that focuses on transforming clinical trials to enhance health equity globally. By leveraging digital health innovations and remote care, it aims to make clinical research more accessible and patient-centered. Lightship provides decentralized and hybrid clinical services that improve patient experience, retention, and trial diversity. Its approach expands the pool of potential participants by moving beyond traditional research centers, effectively meeting patients in their own environments. This strategy helps to eliminate the barriers and inefficiencies associated with conventional clinical trial models, ultimately making medical research more inclusive and effective.

Deep Genomics

Series B in 2020
Deep Genomics Inc. is an artificial intelligence therapeutics company based in Toronto, Canada, founded in 2014. The company focuses on developing individualized genetic medicines by utilizing AI systems to enhance various aspects of drug discovery and development, such as target discovery, lead optimization, toxicity assessment, and innovative trial design. Deep Genomics specializes in creating oligonucleotide therapies that address the genetic underpinnings of diseases at the RNA and DNA levels, targeting rare metabolic, ophthalmologic, and neurodegenerative disorders. Its AI-powered platform decodes the complexities of RNA biology, enabling the identification of novel therapeutic targets and mechanisms that traditional methods cannot access. This innovative approach positions Deep Genomics at the forefront of revolutionizing drug discovery, ultimately aiming to provide new treatments for currently untreatable diseases.

Encellin

Seed Round in 2019
Encellin Inc., established in 2016, is a biotechnology company based in San Francisco, California. It specializes in developing innovative thin-film cell encapsulation devices for cell-based therapeutics, aiming to improve the lives of patients with chronic diseases initially focusing on Type 1 diabetes. The company's technology enables encapsulated cells to function as smart molecular factories, providing potential therapeutic solutions.

GEn1E Lifesciences

Seed Round in 2019
GEn1E Lifesciences Inc. is a biotechnology company based in Palo Alto, California, that focuses on developing therapies for inflammatory and age-related diseases. Incorporated in 2018, GEn1E employs a unique artificial intelligence platform to accelerate the creation of immunomodulatory therapies targeted at rare diseases that currently lack effective treatments. The company has built a robust pipeline of over 21 novel immunomodulators and is working to expedite the development of additional therapies to address pressing health challenges. One of its key products, MUC1-ED, is an antibacterial therapy designed to combat pseudomonas infections. GEn1E's innovative approach allows for the rapid advancement of drug development, significantly reducing time and costs compared to traditional methods in the pharmaceutical industry. The company's experienced team, formed from notable backgrounds in drug development and machine learning, has made substantial progress in a short period, with the aim of delivering life-saving treatments to patients in need.

Cellino

Venture Round in 2019
Cellino is focused on developing a scalable, automated biomanufacturing system aimed at producing personalized cell therapies. The company's innovative platform leverages AI-guided laser editing to generate autologous induced pluripotent stem cells (iPSCs) efficiently and at scale. By utilizing image-guided machine learning, single-cell laser processing, and robotics, Cellino seeks to make advanced, potentially curative treatments accessible for a range of chronic degenerative diseases, including vision loss and Parkinson's disease. The company's mission is to transform healthcare by enabling personalized therapies that can significantly improve patient outcomes and overall health.

Prellis Biologics

Series A in 2019
Prellis Biologics, Inc. is a biotechnology company based in San Francisco, California, that specializes in bioprinting human tissues for drug development and organ transplantation. Founded in 2016, the company focuses on overcoming the challenges of creating vascularized human tissues and organs, aiming to revolutionize healthcare. Its innovative technology allows for the precise engineering of human tissues, including lymph node organoids, which can replicate human immune responses for various applications such as antibody discovery and tumor-immune modeling. Prellis Biologics offers a range of products, including TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X, which collectively enhance early-stage drug discovery and translational pharmacology.

BioAge Labs

Series B in 2019
BioAge Labs, Inc. is a biotechnology company focused on developing therapies to treat aging and age-related diseases. The company utilizes a proprietary systems biology and artificial intelligence platform to identify significant drug targets that influence aging, leveraging extensive datasets to uncover the molecular drivers of age-related pathologies. Among its key offerings is BGE-117, a hypoxia-inducible factor prolyl hydroxylase inhibitor that activates HIF-1 target genes involved in various biological processes, including tissue regeneration and vascular remodeling. Another notable product is BGE-175, an orally administered inhibitor targeting the prostaglandin D2 DP1 signaling pathway, which is linked to an increased risk of mortality and infections, including those associated with immune aging. Founded in 2015 and headquartered in Richmond, California, BioAge Labs is dedicated to harnessing the biology of human aging to create innovative therapies for metabolic and age-related diseases.

Loop Genomics

Series A in 2018
Loop Genomics is a platform technology for long-read DNA sequencing. Loop Genomics technology transforms short-read DNA sequencers into high-throughput, long-read, single-molecule DNA sequencing machines. Loop Genomics long-read DNA sequencing technology provides phased sequencing solutions across a diverse repertoire of research and clinical applications. Sequencing of partial rRNA gene sequences results in reduced phylogenetic resolution. Full-length, high-throughput, phased sequencing that covers all 16S variable regions is becoming the gold standard for profiling the microbiome. Achieve the highest resolution microbial community profiling with long-read, next-generation sequencing of the microbiome. Characterizing polymorphisms in HLA genes inside and outside of the protein-coding regions is important for organ transplantation compatibility testing and for strengthening causality association studies. The length of homologous sequences between HLA alleles extends beyond the capabilities of short-read sequencing platforms, resulting in diploid ambiguities and a reliance on imputation. Sequence full-length HLA DNA and/or RNA with phased, high throughput, long-read sequencing that resolves allelic discrimination and diploid ambiguity. Viral genetic variability is a major determinant of viral drug resistance and viral vaccine efficacy. Accurately mapping viral genetic variability is a critical step in choosing the optimal course of therapy and developing efficacious vaccines. Key mutations are typically located throughout long stretches of viral genomes, making the retrieval of critical phased data challenging using short-read sequencing technology. Use phased, high-throughput DNA sequencing technology to map key mutations at the quasi-species level and generate a complete phased map of viral populations.

Scipher Medicine

Series A in 2018
Scipher Medicine Corporation is a biotechnology company based in Waltham, Massachusetts, that specializes in precision medicine for patients with autoimmune and cardiovascular diseases. The company has developed a molecular technology platform that utilizes blood samples to analyze RNA and predict patient responses to drug therapies. Its primary offerings include PrismDx tests, which identify patients who may not respond to certain medications, ensuring they can be prescribed alternative treatments. Notably, the PrismRA test assesses patients with rheumatoid arthritis to determine their likelihood of responding to anti-TNF therapies, while PrismUC serves a similar purpose for patients with ulcerative colitis. By focusing on the underlying disease biology rather than just symptoms, Scipher Medicine aims to optimize treatment from the outset, potentially reducing the healthcare costs associated with ineffective therapies. Established in 2013 and rebranded in 2015, Scipher Medicine is committed to transforming drug prescription practices and advancing drug development through its innovative approach.

Viome Life Sciences

Series B in 2018
Viome Life Sciences, established in 2016 and headquartered in Bellevue, Washington, specializes in providing comprehensive health insights through its proprietary at-home clinical-grade tests. The company analyzes RNA from stool samples, along with other bodily fluids, to determine the makeup of microbial communities, offering personalized recommendations for diet and lifestyle based on the results. Viome's services aim to empower individuals to track their microbiome health, mitochondrial health, cellular health, and biological age, ultimately aiding in the prevention and reversal of chronic diseases. The company operates as a subsidiary of BlueDot LLC and sells its products through distributors and online channels.

BioConsortia

Series D in 2018
BioConsortia, Inc. is an agricultural biotechnology company that specializes in the discovery, development, and commercialization of microbial consortia for seed treatment and soil additive products aimed at enhancing agricultural yield. Founded in 2014 and headquartered in Davis, California, the company utilizes a proprietary Advanced Microbial Selection process to identify beneficial microbial consortia that improve crop traits, such as fertilizer utilization, plant growth, and resilience against environmental stresses. BioConsortia's products include bio fungicides, bio nematicides, bio insecticides, and biostimulants, which contribute to increased crop yields while reducing reliance on chemical inputs. The company operates research and development facilities in both New Zealand and the United States, focusing on leveraging complex plant-microbe interactions to enhance agricultural productivity and sustainability.

Eligo Bioscience

Series A in 2017
Eligo Bioscience S.A.S is a biotechnology company founded in 2014 and based in Paris, France, specializing in the development of Eligobiotics, a novel class of antimicrobials. These therapeutics are designed to target specific bacteria based on their genomic information, utilizing a combination of CRISPR/Cas technology and engineered phage capsids. This advanced approach allows Eligo to create precision antibiotics aimed at eradicating resistant pathogens and virulent bacteria within the human microbiome. The applications of Eligobiotics extend beyond pharmaceuticals; they also encompass areas such as cosmetics and biodefense, addressing a variety of bacteria-associated diseases and offering next-generation solutions to combat superbugs.

Deep Genomics

Series A in 2017
Deep Genomics Inc. is an artificial intelligence therapeutics company based in Toronto, Canada, founded in 2014. The company focuses on developing individualized genetic medicines by utilizing AI systems to enhance various aspects of drug discovery and development, such as target discovery, lead optimization, toxicity assessment, and innovative trial design. Deep Genomics specializes in creating oligonucleotide therapies that address the genetic underpinnings of diseases at the RNA and DNA levels, targeting rare metabolic, ophthalmologic, and neurodegenerative disorders. Its AI-powered platform decodes the complexities of RNA biology, enabling the identification of novel therapeutic targets and mechanisms that traditional methods cannot access. This innovative approach positions Deep Genomics at the forefront of revolutionizing drug discovery, ultimately aiming to provide new treatments for currently untreatable diseases.

Karius

Series A in 2017
Karius, Inc. is a life sciences company based in Redwood City, California, with an additional office in Menlo Park. Founded in 2014, Karius specializes in generating genomic insights for infectious diseases through its innovative Karius Test. This non-invasive blood test utilizes sequencing of microbial cell-free DNA to identify and quantify a wide range of pathogens, including bacteria, DNA viruses, fungi, and parasites. The Karius Test is particularly useful in the diagnosis of complicated pneumonia, infections in immunocompromised patients, and endocarditis, enabling clinicians to make rapid and informed treatment decisions. Karius operates a CLIA-certified and CAP-accredited laboratory, providing high-complexity clinical laboratory testing and offering services for pathogen biomarker detection aimed at biopharmaceutical companies. The company is dedicated to advancing the understanding and management of infectious diseases, striving for a future where these conditions pose less of a threat to human health.

Viome Life Sciences

Series A in 2017
Viome Life Sciences, established in 2016 and headquartered in Bellevue, Washington, specializes in providing comprehensive health insights through its proprietary at-home clinical-grade tests. The company analyzes RNA from stool samples, along with other bodily fluids, to determine the makeup of microbial communities, offering personalized recommendations for diet and lifestyle based on the results. Viome's services aim to empower individuals to track their microbiome health, mitochondrial health, cellular health, and biological age, ultimately aiding in the prevention and reversal of chronic diseases. The company operates as a subsidiary of BlueDot LLC and sells its products through distributors and online channels.

Genalyte

Series D in 2016
Genalyte, Inc. is a clinical and diagnostic life sciences company based in San Diego, California, that specializes in rapid diagnostic testing solutions for healthcare providers, patients, and researchers. Founded in 2007, Genalyte has developed a unique technology platform employing silicon photonic biosensors to quantify the interactions between biomolecules, such as antibodies and proteins. This innovative approach allows for the direct measurement of protein binding and nucleic acid hybridization, facilitating the monitoring of autoimmune diseases, cancer biomarker screening, and the detection of infectious agents, including Ebola. The company's Maverick platform enables rapid testing in various healthcare settings, with results typically available in under thirty minutes, thereby enhancing patient care and improving resource efficiency within the healthcare system.

BioConsortia

Series C in 2016
BioConsortia, Inc. is an agricultural biotechnology company that specializes in the discovery, development, and commercialization of microbial consortia for seed treatment and soil additive products aimed at enhancing agricultural yield. Founded in 2014 and headquartered in Davis, California, the company utilizes a proprietary Advanced Microbial Selection process to identify beneficial microbial consortia that improve crop traits, such as fertilizer utilization, plant growth, and resilience against environmental stresses. BioConsortia's products include bio fungicides, bio nematicides, bio insecticides, and biostimulants, which contribute to increased crop yields while reducing reliance on chemical inputs. The company operates research and development facilities in both New Zealand and the United States, focusing on leveraging complex plant-microbe interactions to enhance agricultural productivity and sustainability.

Siolta Therapeutics

Venture Round in 2016
Siolta Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing microbiome-based therapeutics and diagnostics aimed at preventing and treating chronic inflammatory diseases, particularly asthma and atopic conditions. Founded in 2016 and headquartered in San Francisco, California, the company utilizes its extensive understanding of the developing gut microbiome to promote immune tolerance. Siolta Therapeutics is advancing pharmaceutical-grade anaerobic organisms and is currently in phase 2 of development for its products. By leveraging insights from human microbiome studies, the company aims to create targeted microbial therapeutics and companion diagnostics that facilitate precision medicine in the management of inflammatory diseases.

Luminist

Seed Round in 2016
Luminist, Inc. is a biomedical company focused on developing a diagnostic platform aimed at the early detection and diagnosis of liver disease. Established in 2015 and located in Newark, California, Luminist operates as a subsidiary of DiscernDx. The company's innovative platform leverages data-driven methodologies to transform biochemical data into essential health information. This enables healthcare providers to deliver comprehensive insights regarding liver diseases and cancer screening through a single diagnostic test, enhancing patient care and facilitating timely medical intervention.

Quartzy

Series B in 2016
Quartzy Inc. is a company that offers an online lab management platform aimed at scientists in laboratories, academic institutions, and pharmaceutical and biotechnology companies globally. Founded in 2007 and headquartered in Palo Alto, California, Quartzy provides a comprehensive solution that includes an extensive catalog of over three million lab supplies, supported by thousands of top suppliers. The platform is designed to streamline the management of laboratory inventories, facilitate communication among lab personnel, consolidate orders, and track inventory efficiently. With a user base of approximately 200,000 scientists across 13,000 labs, Quartzy aims to save time and reduce costs for its clients by optimizing resource management in scientific environments.

Genalyte

Series C in 2015
Genalyte, Inc. is a clinical and diagnostic life sciences company based in San Diego, California, that specializes in rapid diagnostic testing solutions for healthcare providers, patients, and researchers. Founded in 2007, Genalyte has developed a unique technology platform employing silicon photonic biosensors to quantify the interactions between biomolecules, such as antibodies and proteins. This innovative approach allows for the direct measurement of protein binding and nucleic acid hybridization, facilitating the monitoring of autoimmune diseases, cancer biomarker screening, and the detection of infectious agents, including Ebola. The company's Maverick platform enables rapid testing in various healthcare settings, with results typically available in under thirty minutes, thereby enhancing patient care and improving resource efficiency within the healthcare system.

Editas Medicine

Series B in 2015
Editas Medicine is a clinical-stage biotechnology company based in Cambridge, Massachusetts, with an additional site in Boulder, Colorado. Founded in 2013, the company focuses on the discovery and development of genome editing therapeutics, primarily utilizing its proprietary CRISPR/Cas9 technology. This innovative platform enables precise molecular modifications at the genetic level, with the aim of treating a wide array of serious diseases by addressing their underlying causes. Editas Medicine has established a strong intellectual property portfolio, which includes numerous patents related to foundational genome editing technologies and advancements that facilitate the translation of research into viable human therapeutics. The company's mission is to pioneer transformative genomic medicines that can significantly improve patient outcomes across various genetic disorders.

20n

Seed Round in 2015
20n is a biotechnology company that focuses on engineering microbes through advanced algorithms to produce valuable chemicals for therapeutic and industrial applications. Their innovative technology has successfully demonstrated the ability to create bacteria capable of synthesizing Paracetamol, a widely used pain reliever, representing a significant breakthrough in bioproduction methods. Additionally, 20n is developing an open-source platform that allows users to predict DNA edits and design custom fermentation organisms, facilitating the discovery of new molecules and more efficient production processes. The company's data mining capabilities further enhance their potential to identify and produce a wide spectrum of biologically-derived chemicals, positioning them at the forefront of synthetic biology and biomanufacturing.

BioConsortia

Series B in 2014
BioConsortia, Inc. is an agricultural biotechnology company that specializes in the discovery, development, and commercialization of microbial consortia for seed treatment and soil additive products aimed at enhancing agricultural yield. Founded in 2014 and headquartered in Davis, California, the company utilizes a proprietary Advanced Microbial Selection process to identify beneficial microbial consortia that improve crop traits, such as fertilizer utilization, plant growth, and resilience against environmental stresses. BioConsortia's products include bio fungicides, bio nematicides, bio insecticides, and biostimulants, which contribute to increased crop yields while reducing reliance on chemical inputs. The company operates research and development facilities in both New Zealand and the United States, focusing on leveraging complex plant-microbe interactions to enhance agricultural productivity and sustainability.

GreenLight Biosciences

Series A in 2013
GreenLight Biosciences, Inc. is a biotechnology company headquartered in Medford, Massachusetts, with an additional location in North Carolina. Founded in 2008, the company specializes in developing RNA-based solutions for agricultural and pharmaceutical purposes. It offers a proprietary technology platform that enables the efficient and cost-effective production of high-quality RNA, facilitating advancements in vaccine development, pandemic response, crop management, and the protection of pollinators. GreenLight develops mRNA-based vaccine candidates, including those aimed at preventing SARS-CoV-2 infections, and engages in collaborative efforts with industry leaders to further enhance its offerings. Through its innovative approach, GreenLight aims to contribute significantly to sustainable global development and food security.

Quartzy

Series A in 2013
Quartzy Inc. is a company that offers an online lab management platform aimed at scientists in laboratories, academic institutions, and pharmaceutical and biotechnology companies globally. Founded in 2007 and headquartered in Palo Alto, California, Quartzy provides a comprehensive solution that includes an extensive catalog of over three million lab supplies, supported by thousands of top suppliers. The platform is designed to streamline the management of laboratory inventories, facilitate communication among lab personnel, consolidate orders, and track inventory efficiently. With a user base of approximately 200,000 scientists across 13,000 labs, Quartzy aims to save time and reduce costs for its clients by optimizing resource management in scientific environments.

LS9

Series D in 2010
LS9, known as the Renewable Petroleum Company, is a privately-held industrial biotechnology firm based in South San Francisco, California. The company focuses on the development and production of patent-pending UltraClean fuels and sustainable chemicals utilizing synthetic biology. By harnessing advanced industrial synthetic biology techniques, LS9 aims to create renewable petroleum biofuels that serve as eco-friendly alternatives to traditional fossil fuels.

LS9

Series C in 2009
LS9, known as the Renewable Petroleum Company, is a privately-held industrial biotechnology firm based in South San Francisco, California. The company focuses on the development and production of patent-pending UltraClean fuels and sustainable chemicals utilizing synthetic biology. By harnessing advanced industrial synthetic biology techniques, LS9 aims to create renewable petroleum biofuels that serve as eco-friendly alternatives to traditional fossil fuels.

LS9

Series B in 2007
LS9, known as the Renewable Petroleum Company, is a privately-held industrial biotechnology firm based in South San Francisco, California. The company focuses on the development and production of patent-pending UltraClean fuels and sustainable chemicals utilizing synthetic biology. By harnessing advanced industrial synthetic biology techniques, LS9 aims to create renewable petroleum biofuels that serve as eco-friendly alternatives to traditional fossil fuels.

LS9

Series A in 2007
LS9, known as the Renewable Petroleum Company, is a privately-held industrial biotechnology firm based in South San Francisco, California. The company focuses on the development and production of patent-pending UltraClean fuels and sustainable chemicals utilizing synthetic biology. By harnessing advanced industrial synthetic biology techniques, LS9 aims to create renewable petroleum biofuels that serve as eco-friendly alternatives to traditional fossil fuels.

Codon Devices

Series B in 2006
Codon Devices is a biotechnology company, engages in developing, constructing, and delivering synthetic biology products for research. The company focuses on discovering and manufacturing synthetic biological parts. Its BioLOGIC Engineering Platform combines sophisticated design algorithms with assay and protein engineering capabilities to result in a system for the design, discovery, and optimization of proteins for specific applications; and BioFAB Production Platform, which produces synthetic genes.

Vivodyne

Vivodyne is a biotechnology company that specializes in developing an advanced automated robotic system aimed at discovering innovative drugs and cellular therapies. The company has created a microfluidic bioengineering platform that focuses on single-cell 4D phenomics, allowing for a detailed exploration of biological complexities. Its technology enables the cultivation of highly realistic human tissue models for drug discovery, incorporating an integrated confocal microscope. This platform not only accelerates the drug development process but also allows researchers to formulate tunable mixtures of compounds and cell therapies. Through its unique approach, Vivodyne seeks to advance the understanding of human health and facilitate the creation of effective treatments for various diseases.

NewLimit

NewLimit is a biotechnology company focused on addressing age-related diseases to enhance the human health span. It is engaged in the development of epigenetic reprogramming therapies aimed at reversing the aging process and improving life expectancy. By utilizing advanced techniques such as single-cell sequencing, NewLimit aims to rejuvenate tissue across the entire body, targeting diseases that currently have significant unmet medical needs. Through its innovative approach, the company seeks to provide effective solutions for extending health and vitality in aging populations.
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