European Innovation Council

ATXA Therapeutics Limited is a pharmaceutical company based in Dublin, Ireland, focused on developing novel small molecule drugs for the treatment of pulmonary arterial hypertension (PAH). Established in 2015 as a spin-out from University College Dublin, the company has leveraged over 20 years of research and more than €15 million in grant funding to advance its clinical trials and secure marketing authorization for its therapies. ATXA's innovative approach involves targeting human thromboxane receptors to enhance vasodilation and reduce vasoconstriction, addressing significant unmet medical needs in PAH and other cardiovascular conditions. The team comprises experts in various fields, including cardiovascular and cancer biology, drug discovery, and preclinical pharmacokinetics, positioning ATXA to develop more effective treatments than current standard care options. The company aims to improve treatment outcomes for patients suffering from PAH and related conditions through its advanced therapies.

Selio is a simple, effective and patent protected technology. The Selio prototype has been rigorously tested in the lab and in subsequent acute pre-clinical in vivo studies with very positive results.

Ovagen is a biotechnology company that has developed the process of producing germ free (GF) chicken eggs and GF birds in commercial quantities for use primarily in the pharmaceutical industry. Ovagen can also provide a Contract Research Service and has extensive expertise in SPF poultry & rodent housing & husbandry, in specific poultry & rodent research technologies to GMP standards and in avian transgenics.

Loci Orthopaedics Limited is a medical technology company based in Upper Newcastle, Ireland, focused on developing innovative solutions for orthopedic care. Established in 2017, the company specializes in the InDx implant, which is designed to treat arthritis in the thumb base joint. This implant uniquely mimics the natural motions of the thumb joint, providing a less invasive and easier insertion method compared to existing surgical options. Loci Orthopaedics also emphasizes evidence-based designs in its products, aiming to address significant unmet clinical needs in orthopedic extremities.

Loci Orthopaedics Limited is a medical technology company based in Upper Newcastle, Ireland, focused on developing innovative solutions for orthopedic care. Established in 2017, the company specializes in the InDx implant, which is designed to treat arthritis in the thumb base joint. This implant uniquely mimics the natural motions of the thumb joint, providing a less invasive and easier insertion method compared to existing surgical options. Loci Orthopaedics also emphasizes evidence-based designs in its products, aiming to address significant unmet clinical needs in orthopedic extremities.

Ovagen is a biotechnology company that has developed the process of producing germ free (GF) chicken eggs and GF birds in commercial quantities for use primarily in the pharmaceutical industry. Ovagen can also provide a Contract Research Service and has extensive expertise in SPF poultry & rodent housing & husbandry, in specific poultry & rodent research technologies to GMP standards and in avian transgenics.

Venari Medical Limited, founded in 2018 and based in Galway, Ireland, develops innovative medical devices aimed at treating chronic venous diseases (CVD). The company's flagship product, BioVena, employs the body's natural healing processes to provide a more effective and less invasive treatment option for conditions such as varicose veins and venous ulcers. Venari Medical seeks to address the significant gap in treatment, as only a small fraction of the 120 million individuals suffering from venous disease in the US and EU receive adequate care. Their technology not only offers a safer alternative to existing methods but also targets the underserved population of venous ulcer patients who currently rely on ineffective compression bandaging. By widening the indications for superficial venous ablation, Venari Medical aims to reduce the annual costs associated with venous ulcers, which total approximately $33 billion for insurers in these regions. The company's commitment to patient-centered solutions positions it to disrupt traditional treatment practices that have seen limited innovation in recent years.

Intelligent Implants specializes in developing wireless implantable electronics designed to stimulate, steer, and monitor bone growth. The company provides electrotherapeutic devices that address various diseases and support the recovery of bone and other tissues. By integrating data, engineering, and medicine, Intelligent Implants creates innovative, active, and connected medical devices aimed at improving patient treatment and assisting healthcare professionals in their decision-making processes. Founded in 2014 in Cork, the company was established by Erik Zellmer, Rory Murphy, Martin Larsson, and John Zellmer.

OneProjects Design and Innovation Ltd. develops healthcare technologies for the treatment of cardiac arrhythmias. It offers VERAFEYE, a connected platform technology to revolutionize the treatment of AFib and cardiac arrhythmias. The company was incorporated in 2017 and is based in Dublin, Ireland.

OneProjects Design and Innovation Ltd. develops healthcare technologies for the treatment of cardiac arrhythmias. It offers VERAFEYE, a connected platform technology to revolutionize the treatment of AFib and cardiac arrhythmias. The company was incorporated in 2017 and is based in Dublin, Ireland.

RemedyBio is an immunology-focused discovery and development company based in Dublin, Ireland. It has pioneered a new approach to understanding the immune system and the discovery of new therapies.

Vivasure Medical Limited is a medical device company based in Galway, Ireland, focused on the research, development, and manufacturing of arterial and venous closure devices utilizing its proprietary PerQseal technology. The company specializes in creating polymer implants and delivery systems aimed at facilitating minimally invasive vessel closures in cardiology, interventional radiology, and vascular surgery. Its flagship product is an absorbable patch-based large-bore percutaneous closure device, specifically designed to close large arteriotomies during transcatheter procedures like transcatheter aortic valve replacement and endovascular aneurysm repair. Established in 2008, Vivasure Medical aims to enhance patient outcomes in vascular access procedures through innovative medical solutions.

Gasgon Medical is a medical device company focused on enhancing the safety and efficiency of intravenous (IV) infusions. By developing innovative products, the company addresses the challenges faced by medical staff in administering IV medications, aiming to reduce potential harm to patients. Gasgon Medical's devices are designed to minimize the risk of Vascular Air Embolism, thereby improving overall patient outcomes and supporting clinicians in delivering high-quality healthcare.

SepTec is developing and commercializing a revolutionary sample-to-answer sepsis diagnostic device that can rapidly detect pathogens in whole blood.

Provizio Ltd provides an accident prevention technology platform, which includes proprietary vision sensors and machine learning for detecting danger. It also offers BETA program. The company was incorporated in 2019 and is based in Limerick, Ireland.

SepTec is developing and commercializing a revolutionary sample-to-answer sepsis diagnostic device that can rapidly detect pathogens in whole blood.

SiriusXT Limited, incorporated in 2015 and headquartered in Dublin, Ireland, specializes in the development and manufacture of a soft x-ray microscope known as the SXT system. This innovative benchtop system enables researchers to produce high-resolution images of biological samples in their own laboratories. Utilizing a vacuum-based laser-produced plasma soft x-ray light source, the SXT system facilitates soft x-ray tomography, akin to a CT scan for cells, which is essential for life scientists studying the 3D internal structures of cells in their natural, fully hydrated states. The SXT system is primarily marketed to researchers in disease research and drug discovery, including pharmaceutical companies, biotechnologists, and clinicians, helping them to better understand disease pathways, protein-drug interactions, and bio-engineering processes. As the first high-throughput, bench-top soft x-ray tomography system, it can produce detailed 3D tomographs of entire cells in minutes.

RemedyBio is an immunology-focused discovery and development company based in Dublin, Ireland. It has pioneered a new approach to understanding the immune system and the discovery of new therapies.

SiriusXT Limited, incorporated in 2015 and headquartered in Dublin, Ireland, specializes in the development and manufacture of a soft x-ray microscope known as the SXT system. This innovative benchtop system enables researchers to produce high-resolution images of biological samples in their own laboratories. Utilizing a vacuum-based laser-produced plasma soft x-ray light source, the SXT system facilitates soft x-ray tomography, akin to a CT scan for cells, which is essential for life scientists studying the 3D internal structures of cells in their natural, fully hydrated states. The SXT system is primarily marketed to researchers in disease research and drug discovery, including pharmaceutical companies, biotechnologists, and clinicians, helping them to better understand disease pathways, protein-drug interactions, and bio-engineering processes. As the first high-throughput, bench-top soft x-ray tomography system, it can produce detailed 3D tomographs of entire cells in minutes.

Rockfield Medical Devices is an innovative SME in the area of human centered design process in the medical device industry. The company is led by its founder and has a very strong team made up of several acknowledged experts from the medical device industry and from research and design. Rockfield aims to be a leading innovator in the enteral feeding market globally and strives to achieve exemplary end user satisfaction with their plug and play technologies through innovative design, usability and mobility.

Rockfield Medical Devices is an innovative SME in the area of human centered design process in the medical device industry. The company is led by its founder and has a very strong team made up of several acknowledged experts from the medical device industry and from research and design. Rockfield aims to be a leading innovator in the enteral feeding market globally and strives to achieve exemplary end user satisfaction with their plug and play technologies through innovative design, usability and mobility.

Bluedrop Medical Limited, founded in 2014 and based in Galway, Ireland, develops and commercializes an Internet of Things-enabled device that facilitates early detection of diabetic foot ulcers. The device conducts daily scans of patients' feet and transmits the data to the cloud for analysis using advanced algorithms. This technology is designed to identify skin abnormalities early, thereby reducing the risk of amputation, a serious complication faced by many diabetics due to peripheral neuropathy. With an estimated 25% of diabetics likely to develop foot ulcers, the company's innovation addresses a critical healthcare need and aims to improve patient outcomes while potentially lowering healthcare costs associated with diabetes-related amputations.

GEOWOX LIMITED provides AI powered valuations for the residential real estate sector in Irish and British markets. The company provides property and area valuation services for lenders and investors. Its services for lenders include new lead generation and qualification, re-valuation and fraud detection, and CRR and NPL alignment; and investors include assess new business opportunities, leverage data to assess risk, and analyze trends and insights. GEOWOX LIMITED was incorporated in 2017 and is based in Dublin, Ireland.