MedTech Innovator

CardiaCare is focused on developing a wearable medical device aimed at the non-invasive treatment and monitoring of atrial fibrillation (AFib) in patients. Utilizing a closed-loop approach and machine learning algorithms, the device applies personalized peripheral neuromodulation to elicit a cardiovascular antiarrhythmic response. This innovative technology enables users to effectively reduce the burden of atrial fibrillation and mitigate its precursors, such as premature atrial contractions. As a result, patients can experience rapid clinical and symptomatic relief while managing their condition from the comfort of their homes.

Healthcare X.0 is an online healthcare platform that provides its clients with digitization solutions. The platform provides its clients with health, vascular, patient, onco, nephro, cardio, wound, tele, patient, and diabetic assist database solutions. Healthcare X.0 was launched in 2013 by and is based in Niedersachsen.

CARI Health is a digital health company based in San Diego, California, that specializes in the development of remote medication monitors. Founded in 2015 and incorporated in 2021, the company creates wireless sensors that patients wear on their skin. These sensors continuously transmit real-time data about medication levels to the cloud, allowing clinicians to safely prescribe, dose, and monitor adherence to critical medications. By providing this innovative solution, CARI Health aims to enhance patient care and improve health outcomes through better medication management.

Digma Medical is a clinical stage medical device company established in 2013, focused on innovating treatments for Type-2 Diabetes and related metabolic syndromes, including NASH. The company is developing the DiaGone™, an endoscopic and disposable device that employs advanced laser technology to treat the duodenum without the need for an implant. The Duodenal Glycemic Control™ procedure, which lasts approximately 30 minutes, allows gastroenterologists to use the DiaGone™ to enhance the body's ability to regulate glucose levels. This approach aims to offer patients the potential for long-term remission from Type-2 Diabetes and other metabolic conditions, thereby improving their overall quality of life and health outcomes. Supported by prominent venture capital firms, Digma Medical is dedicated to advancing effective therapies for diabetes management.

Fluid Biomed Inc. is a Calgary-based company that specializes in the development of innovative implantable vascular stents aimed at enhancing patient well-being. Established in 2012, the company focuses on creating a stent designed to gently divert blood flow away from brain aneurysms, facilitating their healing process. Through its commitment to innovation, Fluid Biomed seeks to improve health outcomes and overall quality of life for patients.

Gradient Denervation Technologies develops a endovascular catheter-based medical device to treat pulmonary hypertension. Its medical device aims at reducing pulmonary vascular resistance and improving cardiovascular hemodynamics. The company was incorporated in 2019 and is based in Paris, France.

LiveMetric is a medical device company developing non-invasive sensing and deep data analytics solutions. The company transforming the care and condition-management of hypertension and cardiovascular diseases. Using their own proprietary, non-invasive arterial pressure technology, they provide a wearable, non-invasive medical device which enables AI-augmented care and condition management treatment services management. LiveMetric delivers high fidelity arterial pressure waveforms and detailed activity mapping of the single user at any time. They seek to empower individuals, payors, self-insured employers and healthcare providers with an accurate, fact-based, personalized care platform that has the potential for improving the care and lives of over 1 Billion people worldwide who suffer from these conditions. The company's goal is to provide prescribed patients, caregivers, and payors with pertinent data and detailed daily activity mapping.

Garwood Medical Devices, LLC develops and manufactures medical devices related to infection, perio-prosthetic, and wound healing. It offers BioPrax, a minimally invasive device that targets and eliminates biofilm infections on prosthetic knee implants during early intervention procedures. Garwood Medical Devices, LLC was formerly known as Enermed, LLC and changed its name to Garwood Medical Devices, LLC in December 2015. Garwood Medical Devices, LLC was incorporated in 2014 and is based in Buffalo, New York.

Robotic Hospital Nutrition Management Systems

Endiatx is a medical device manufacturing company that specializes in developing a series of pill-sized robots to perform remote diagnosis. Its unique propulsion system which allows our pill robots to actively navigate the entire length of the GI tract is approximately 30 minutes with real-time video control. It was founded in 2019 and headquartered in Redwood City, California.

Tricog Health Services Pvt Limited, established in 2014 and headquartered in Bengaluru, India, specializes in cloud-connected ECG devices that facilitate the interpretation and analysis of electrocardiography (ECG) reports. The company addresses critical gaps in cardiac care, particularly in regions with limited access to diagnostic tools and trained personnel. Tricog's offerings include the InstaECG and VCardia applications, which enhance the speed and accuracy of cardiac monitoring. The company leverages artificial intelligence to provide real-time reporting and analysis of ECG results, enabling quicker diagnosis of cardiac events. This timely intervention is crucial, as survival rates for heart attack patients significantly improve with prompt treatment, yet many patients experience delays in diagnosis and care. Tricog Health aims to bridge these gaps, potentially saving millions of lives by ensuring that primary care clinics are equipped with affordable and efficient ECG solutions. With a presence in Singapore, Malaysia, and China, Tricog is positioned to expand its impact in the global healthcare landscape.

Bright Uro is an early-stage medical technology company. It is building the next generation of diagnostic devices for Urology. Utilizing advanced hardware, software, and data science can unlock new data streams and offer actionable insight for clinicians.

EvoEndo is a medical technology company focused on advancing unsedated endoscopic procedures for both pediatric and adult patients. The company has developed a system that incorporates sterile, single-use flexible endoscopes, a virtual reality-based distraction method, and a comprehensive software integration platform. This innovative approach allows for routine endoscopies to be performed in a clinical setting without the need for general anesthesia or sedation. By streamlining the process, EvoEndo's technology aims to decrease complexity, lower costs, and alleviate the anxiety often associated with endoscopic procedures, making them more accessible and manageable for patients and healthcare providers alike.

Corveus Medical is focused on creating innovative solutions to prevent heart failure through the development of a neuromodulation device. This catheter-based technology aims to safely and effectively access nerve tissue, enabling nerve ablation for improved treatment outcomes. By employing minimally invasive methods, Corveus Medical seeks to alleviate both the clinical and economic burdens associated with heart failure, marking a significant advancement in the field of cardiac care. The company is committed to delivering consistent results and enhancing patient quality of life through its pioneering approach to heart failure treatment.

Discure Technologies is focused on creating a minimally invasive, implantable bioelectronic device aimed at treating degenerative disc disease (DDD). This innovative device employs a novel bioelectric technique that addresses the root cause of DDD, allowing physicians to alleviate pain and restore normal disc function in patients. By promoting healing of the affected discs, Discure seeks to improve the quality of life for individuals suffering from this condition.

SUTUREGARD Medical, Inc. is an Oregon-based company that develops, manufactures, and supplies innovative wound closure devices. Founded in 2014 and headquartered in Portland, the company offers products designed to enhance surgical outcomes. Its flagship device, SUTUREGARD ISR, facilitates stress-relaxation during wound healing, addressing issues such as skin stretch and reduced tension on surgical sites. Additionally, the HEMIGARD ARS serves as an adhesive retention suture device that reinforces skin strength, allowing for linear wound closure without the risk of skin ripping. By commercializing these advanced surgical products, SUTUREGARD Medical aims to simplify the wound closure process and improve patient recovery.

Endoron Medical specializes in the development of innovative medical devices aimed at improving the treatment of abdominal aortic aneurysms. The company has created an endovascular suture-like device designed for use in endovascular aneurysm repair. This fixation device enhances the performance of endografts, providing a more effective and durable sealing solution. By leveraging advanced technology, Endoron Medical aims to facilitate better patient outcomes during procedures for abdominal aortic aneurysms, thereby addressing a critical need in vascular surgery.

MastOR SAS is a medical device company based in Paris, France, founded in 2019. The company focuses on developing a surgical robot designed to assist with laparoscopy, a minimally invasive surgical technique. This innovative platform aims to enhance access to advanced surgical procedures for surgeons and improve resource utilization in operating rooms. By providing tools that facilitate laparoscopy, MastOR seeks to advance surgical practices and patient care.

CloudMedx Inc. is a software development company based in Palo Alto, California, that specializes in artificial intelligence solutions for the healthcare sector. Founded in 2014, the company focuses on extracting key clinical concepts from electronic health records to provide actionable insights that enhance clinical operations, documentation, and patient care. Its platform transforms disparate healthcare data into a cohesive view that supports better clinical, treatment, and diagnostic outcomes. By integrating with existing systems, CloudMedx aims to facilitate collaboration among healthcare providers, payers, and patients. The company offers tools for patient engagement, risk stratification, and timely notifications for care needs, serving a diverse clientele that includes managed care organizations, accountable care organizations, and various healthcare facilities. The mission of CloudMedx is driven by a commitment to improve healthcare delivery, stemming from personal experiences related to misdiagnosis and the inefficiencies within the healthcare system.

Oxford Endovascular are developing a novel treatment for treating brain aneurysms. The Oxford technology uses a special laser-cut metal alloy which has a shape-memory. It can be posted into a catheter during surgery, inserted into the brain and opened up into a tiny tube mesh (‘flow diverter’) that fits into the natural shape of the blood vessel. This diverts the blood away from the aneurysm, allowing it to heal.

ConKay Medical Systems is an early-stage medical device company focused on developing innovative solutions to address valvular regurgitation in patients suffering from progressive heart failure. The company's technology is centered around annular repair, which targets the primary cause of functional regurgitation while preserving the integrity of healthy leaflets. This approach aims to enhance the effectiveness of cardiovascular care, providing healthcare professionals with advanced tools to better manage this condition.

Anumana is an AI-driven company that develops ECG algorithms enabling early disease diagnosis and intervention. Anumana harnesses industry-leading AI and translational science to decode the electrocardiogram (ECG) – like a deep predictive tool and biomarker of disease, empowering care providers to help patients early.

52 North Health is focused on enhancing healthcare for cancer patients, specifically those undergoing chemotherapy, by providing a portable and easy-to-use medical device. This device employs artificial intelligence to assess the risk of neutropenic sepsis, a serious and potentially fatal side effect of chemotherapy. Through a finger prick blood test and a corresponding digital platform, the device measures a patient's neutrophil count and C-reactive protein (CRP) levels at home. This functionality allows for timely identification of patients at risk of sepsis, thereby improving their safety and quality of life. By facilitating rapid management of their condition, 52 North Health offers a reliable and cost-effective solution for cancer patients.

Actionable, accessible, and affordable feedback system for preventive health maintenance.

Aqua Medical, Inc. develops a disruptive, vapor-based, endoscopic, ablation technology to treat gastrointestinal (GI) disease and prevent GI cancers. Its ablation technology includes high temperature water vapor created by a radio frequency generator and delivered endoscopically through proprietary catheters to the GI tract. The company’s platform technology uses a vapor generator system with two catheter types to deliver treatment for multiple diseases throughout the GI tract. The company was incorporated in 2016 and is based in Santa Ana, California.

Endoluxe, Inc. manufactures a portable device to perform endoscopic procedures. The company’s EVS system offers features, such as wireless display, HD camera, voice activation, and auto image stabilization with applications in Urology, Gynecology, Pulmonology, and Orthopedics. Endoluxe, Inc. was incorporated in 2013 and is based in Dunwoody, Georgia.

DermaSensor, Inc. develops a hand-held device that uses artificial intelligence to evaluate skin lesions for cancer. It offers DermaSensor, a device that allows physicians and consumers to perform skin checks in physician offices and patient homes. The company’s device is also used for lesion identification, scanning, photon scattering, and algorithmic analysis. DermaSensor, Inc. was founded in 2009 and is based in Miami, Florida.

SymPhysis Medical focuses on developing innovative medical technologies aimed at treating chronic diseases, with an emphasis on enhancing patient experience and quality of life. The company's flagship product, releaze, addresses malignant pleural effusion (MPE), a common complication in late-stage cancer patients that can lead to severe shortness of breath and chest pain. This therapeutic device is designed for home use, effectively draining excess fluid from the pleural space. By utilizing an active component that enhances fluid removal efficiency, releaze alleviates distressing symptoms and improves treatment accessibility for patients requiring indwelling pleural catheter (IPC) therapies.

Augment Health is a medical device company in the southeast United States. Augment Health is focused on improving patient quality of life and care outcomes, initially focused on the population of catheter users with limited bladder sensation. They have developed a bladder management system that lets patients know when they need to go.

Liquet Medical is a medical device development company focused on improving the treatment of vascular disease through innovative localized drug delivery methods. The company's flagship product, the Versus Catheter, features a dual-tip infusion design, real-time pressure monitoring, and a flow-directed placement balloon. These advancements aim to enhance patient outcomes and promote healthcare sustainability by providing healthcare professionals with more effective tools for managing vascular conditions. Liquet Medical's commitment to developing patented technologies positions it as a significant player in the medical device sector.

SafeBeat Rx replaces a hospitalization with a take-home kit that combines FDA-approved wearables with life-saving ECG software that expands access to proven heart therapies.

PyrAmes is a healthcare technology company focused on transforming the delivery of medical care through advanced sensor measurement. The company has developed a paper-thin, flexible device that enables non-invasive, continuous blood pressure monitoring. This ultra-low power device is designed to be accurate and wireless, making it suitable for patients across all age groups, from newborns to seniors. By providing a pain-free method for blood pressure monitoring, PyrAmes aims to enhance the quality of care offered by healthcare providers, particularly for vulnerable populations such as neonates.

Flosonics is a medical device company that focuses on developing non-invasive sensors to improve the management of critically ill patients. Flosonics's flagship smart-bandage product, the FloPatch, addresses unmet clinical needs of critically ill patients and the physicians, nurses, and paramedics who care for them in the ambulance, emergency department, operating room, and intensive care unit.

Forest Devices, Inc. is a medical device company based in Pittsburgh, Pennsylvania, with an additional office in Canada. Founded in 2014, the company focuses on developing innovative solutions for stroke detection. Its flagship product, AlphaStroke, is a non-invasive, AI-powered device designed for medical personnel to identify strokes in various environments, even before advanced imaging techniques like CT or MRI are available. This portable and durable device can detect both ischemic and hemorrhagic strokes, enabling practitioners to triage patients effectively and improve treatment outcomes. By streamlining the decision-making process in stroke management, AlphaStroke aims to reduce delays in critical care and enhance the overall frequency of stroke treatments.

OncoRes Medical Pty Ltd is an early-stage medical device company based in Nedlands, Australia, founded in 2014. The company specializes in developing a patented imaging technology that provides surgeons with real-time, micro-scale images of tissue stiffness and elasticity during breast cancer surgeries. This innovative tool integrates optical coherence tomography to enhance surgical accuracy, aiding in the differentiation between tumor and healthy tissue. OncoRes collaborates with leading researchers at the University of Western Australia and the Harry Perkins Institute of Medical Research, as well as breast cancer surgeons in the Western Australian public health system. With support from the Medical Research Commercialisation Fund, OncoRes Medical aims to improve clinical applications by enabling precise intraoperative assessments of tissue microstructure, ultimately striving to transform the standard of care in breast cancer treatment.

Bardy Diagnostics, Inc. is a medical device company that specializes in the development and manufacturing of cardiac monitoring solutions, primarily focused on arrhythmia detection. Its flagship product, the Carnation Ambulatory Monitor (CAM), is a lightweight, discreet cardiac patch that can be worn comfortably for up to seven days, even during physical activities like exercise or showering. The CAM is designed with a unique hourglass shape to enhance comfort, particularly for female patients. Complementing the monitor is the BDxCONNECT patient management system, which allows healthcare providers to create and manage patient reports efficiently. By utilizing innovative P-wave centric ECG detection technology, Bardy Diagnostics aims to improve clinical management and outcomes for patients and their physicians. Founded in 2013, the company is headquartered in Seattle, Washington, with additional offices in Houston, Texas, and New Providence, New Jersey.

CloudCath is a company that specializes in developing a remote monitoring platform for peritoneal dialysis patients. Their innovative system utilizes sensor-enabled technology to provide continuous monitoring, allowing for early detection of complications associated with catheter-based treatments. By leveraging Internet of Things (IoT) capabilities, CloudCath's platform enables healthcare providers to remotely oversee patients during their home treatment, significantly reducing the frequency of in-person visits. This approach not only enhances patient safety but also improves the overall management of care for individuals undergoing peritoneal dialysis, ultimately promoting better health outcomes.

HD Medical Group Pty Ltd. designs and develops innovative medical products aimed at the screening and detection of cardiac conditions. The company's primary offerings include the ViScope, an electronic stethoscope featuring a visual display for auscultation, and the ViScope MD, which integrates a phonocardiogram visual display along with a murmur indicator. These products are distributed through various channels, enhancing accessibility for healthcare professionals. Founded in 2005 and headquartered in Melbourne, Australia, HD Medical also maintains additional offices in Sunnyvale, California; St. Leonards, Australia; and Chennai, India. The company is recognized as a global leader in the management of cardiovascular disease, focusing on enabling evidence-based patient diagnosis.

Respirix, Inc. is a medical technology company based in San Francisco, California, specializing in the development of precise analysis sensors for monitoring breath exhalation and cardiogenic oscillations. Founded in 2015, Respirix focuses on creating hardware and software solutions that provide insights into cardiac health, particularly through non-invasive monitoring of the pulmonary vasculature. Its product pipeline addresses various applications, including at-home monitoring and critical care, specifically targeting conditions such as heart failure and hemodynamics. The company's innovative approach integrates digital health tools to enhance the understanding and management of cardiac conditions.

Embolx, Inc. is a medical device manufacturer based in Sunnyvale, California, focused on creating catheter-based systems for cancer treatment. Founded in 2013, the company has developed innovative devices such as the Sniper, a drug delivery balloon microcatheter that enhances the precision of delivering therapeutic agents directly to tumors while minimizing the risk of affecting surrounding healthy tissues. Utilizing a technique known as Low Pressure Embolization (LPE), Embolx's devices regulate pressure to improve drug distribution within the tumor and eliminate non-target delivery. This technology aims to set a new standard in minimally invasive localized cancer therapy, while also addressing conditions such as benign prostatic hyperplasia and uterine fibroids.

Moving Analytics. is a tele-health company dedicated to helping people thrive after heart disease. Our flagship product is Movn a virtual cardiac rehabilitation program that leverages evidence based guidelines, behavioral science, remote monitoring and personalized coaching to help patients recover to full health after a cardiac event. Movn is currently used by the Veterans Affairs Medical Center, Highmark Health Plan, Kaiser Permanente Northwest and many more health systems across the US.

Patchd Inc is a healthcare technology company based in San Francisco, California, founded in 2017. The company specializes in developing a wearable device designed to predict sepsis in outpatient settings. Its wireless patch continuously collects vital sign data, enabling healthcare providers to monitor patients effectively. By employing artificial intelligence algorithms, Patchd's technology facilitates the early detection of life-threatening conditions, particularly when used by hospitals for newly admitted patients. This innovative approach aims to enhance patient care and improve outcomes in post-acute care scenarios.

Koya Medical, Inc. is a company based in Oakland, California, founded in 2018. It focuses on developing a connected wearable platform designed to address the significant unmet needs in the treatment of cancer-related chronic lymphedema and venous diseases. The technology aims to provide a drug-free solution for patients suffering from these conditions, enhancing their quality of life through innovative medical devices.

Venari Medical Limited, founded in 2018 and based in Galway, Ireland, develops innovative medical devices aimed at treating chronic venous diseases (CVD). The company's flagship product, BioVena, employs the body's natural healing processes to provide a more effective and less invasive treatment option for conditions such as varicose veins and venous ulcers. Venari Medical seeks to address the significant gap in treatment, as only a small fraction of the 120 million individuals suffering from venous disease in the US and EU receive adequate care. Their technology not only offers a safer alternative to existing methods but also targets the underserved population of venous ulcer patients who currently rely on ineffective compression bandaging. By widening the indications for superficial venous ablation, Venari Medical aims to reduce the annual costs associated with venous ulcers, which total approximately $33 billion for insurers in these regions. The company's commitment to patient-centered solutions positions it to disrupt traditional treatment practices that have seen limited innovation in recent years.

Pristine Surgical LLC, founded in 2011 and based in Manchester, New Hampshire, has developed a groundbreaking single-use digital imaging platform tailored for surgical and diagnostic rigid endoscopic procedures. The company specializes in single-use digital arthroscopes and laparoscopes that come in a completely sterile kit. By integrating high-definition digital imaging, advanced LED lighting, artificial intelligence, and cloud-based software, Pristine Surgical aims to enhance the efficiency and safety of over 23 million procedures annually. The platform not only improves the surgical experience for patients and healthcare providers but also addresses key concerns such as cost reduction, risk mitigation, and the elimination of cross-contamination associated with reprocessing instruments. Through its innovative technology, Pristine Surgical strives to streamline the entire surgical episode, ultimately improving communication and satisfaction among surgeons and healthcare facilities.

Subtle Medical, Inc., a healthcare technology company, develops medical imaging software for clinical imaging centers and hospitals. Its product includes SubtleMR, an artificial intelligence-based image processing software that reduces image noise and increases image sharpness for non-contrast enhanced magnetic resonance imaging (MRI). It enables to reduce cost, imaging time, and radiation/contrast dose. The company was founded in 2017 and is based in Menlo Park, California.

HEPTA Medical develops a sensor, embedded into a bronchoscopic or percutaneous ablation catheter, which provides temperature-based feedback. This enables real-time dosing to precisely target and ablates pulmonary nodules, the precursor of lung cancer, without the need for surgery or radiation.

ZKR Ortho is engaged in developing innovative medical devices and procedures aimed at alleviating chronic knee pain associated with Condromalacia Patellae, a condition characterized by the degeneration of cartilage and inflammation beneath the patella. This condition affects millions, often leading individuals to delay intervention due to the invasiveness of traditional surgical solutions. ZKR Ortho's approach offers a minimally invasive implant procedure that unloads the patellofemoral joint by elevating the patella tendon, thereby realigning the knee cap towards healthier cartilage. This method not only relieves pain but also promotes mobility and may reduce the necessity for knee replacement surgeries. Founded by Dr. Jeffrey Halbrecht, a leader in minimally invasive arthroscopic techniques, the company holds multiple patents and has developed prototypes for its devices. Currently, ZKR Ortho is in the process of raising capital to support product trials.

EndObetes is a medical device company that develops an endoscopically food delivery solution for treating obesity and diabetes. The company's device shunts food directly from the esophagus to the intestine, bypassing the stomach and duodenum, much like gastric bypass surgery, enabling people to get access to a durable, safe and effective non-surgical treatment for obesity and diabetes. It was founded in 2015 and is based in New York, New York.

ATRO Medical B.V., based in Nijmegen, the Netherlands, specializes in the development of an anatomically shaped polymer-based meniscus implant known as the Trammpolin. This innovative implant is designed to restore the protective function of the meniscus by acting as a spacer in the joint. ATRO Medical emerged as a spin-out from DSM and Radboudumc, leveraging expertise gained from a collaborative initiative that began in 2010, which included universities, private companies, and support from the Dutch government. The company combines clinical, biomechanical, and polymer knowledge to advance the Trammpolin design and its prototype development.

CoapTech, Inc. is a medical device company based in Baltimore, Maryland, founded in 2016. It specializes in developing ultrasound-based solutions for feeding tube placement, primarily through its Point-of-care Ultrasound Magnet Aligned (PUMA-G) System. This innovative system enhances safety by using ultrasound visualization to guide the insertion of gastrostomy tubes, thereby eliminating risks associated with traditional methods such as PEG blind sticks, endoscope reprocessing, and fluoroscopy. CoapTech’s technology, known as Coaptive Ultrasound, utilizes strong rare-earth magnets for device placement and low-cost ultrasound for real-time visual feedback. This approach allows non-surgical providers to perform the percutaneous ultrasound gastrostomy (PUG) procedure efficiently and safely, improving patient care delivery while reducing healthcare costs. The company aims to disrupt multiple medical procedures by providing simpler, safer, and more affordable alternatives, focusing on enhancing access to quality medical services globally.

ThermopeutiX is a privately held company that offers imaginative, innovative and economical solutions to unmet medical needs.

Forest Devices, Inc. is a medical device company based in Pittsburgh, Pennsylvania, with an additional office in Canada. Founded in 2014, the company focuses on developing innovative solutions for stroke detection. Its flagship product, AlphaStroke, is a non-invasive, AI-powered device designed for medical personnel to identify strokes in various environments, even before advanced imaging techniques like CT or MRI are available. This portable and durable device can detect both ischemic and hemorrhagic strokes, enabling practitioners to triage patients effectively and improve treatment outcomes. By streamlining the decision-making process in stroke management, AlphaStroke aims to reduce delays in critical care and enhance the overall frequency of stroke treatments.

Olfactomics is a Finnish university-based spinoff company developing a novel technology for surgical tissue assessment. They focus on improving breast-concerving lumpectomies where residual tumor continues to be an issue. Realtime tissue analysis allows the surgeon to remove the whole tumor in one operation and minimize the resection of healthy tissues.

Previvo is a medical device company focused on preventing genetic diseases through its innovative technology that enhances pre-implantation genetic testing. By offering a more natural and healthier alternative to traditional in vitro fertilization and embryo collection methods, Previvo aims to empower women and couples undergoing assisted reproduction. Its patent-pending device is designed to facilitate pre-implantation genetic diagnosis and screening, helping to ensure healthier outcomes for prospective parents and their future children.

Orbit Genomics applies its proprietary OrbiSeq technology platform to aid in diagnosing and ultimately preventing complex diseases.

AMB Surgical is a developer of innovative medical devices aimed at treating pediatric deformities, particularly scoliosis. The company has created an electro-mechanical smart automated growing rod known as "FLYTE," which allows for precise and frequent non-surgical adjustments through sensor feedback. This technology enhances the capabilities of surgeons in managing complex cases involving pediatric scoliosis, dynamic external fixation for deformity correction, and applications related to long bone lengthening. By providing a solution that minimizes the need for invasive surgical procedures, AMB Surgical aims to improve treatment outcomes for children facing these conditions.

AblaCare is a Paris-based company founded in 2017 that focuses on addressing infertility related to Polycystic Ovary Syndrome (PCOS). The company has developed a minimally invasive procedure designed to restore ovulation in patients with PCOS, offering a more natural and less medicalized approach to pregnancy. This innovative treatment is performed transvaginally under ultrasound guidance, eliminating the need for general anesthesia. The procedure can be conducted in a clinic setting, utilizing techniques similar to those used by fertility specialists in in vitro fertilization (IVF). Through its solution, AblaCare aims to enhance the reproductive health and pregnancy experiences of women affected by PCOS.

Conavi Medical is a healthcare company focused on providing image guidance technologies for minimally invasive cardiovascular procedures.

Soundbite Medical Solutions Inc. is a cardiovascular medical technology company based in Montreal, Canada, specializing in the development and commercialization of innovative medical devices. Founded in 2013, the company focuses on creating a proprietary wire-based device and generator console that utilizes shockwave energy to treat chronic total occlusions (CTOs) within the cardiovascular system. This technology is designed to enhance vessel preparation for patients suffering from peripheral artery disease (PAD) and coronary artery disease (CAD), which collectively impact over 20 million individuals in the United States. Soundbite Medical Solutions aims to improve treatment outcomes for these patients through its advanced therapeutic solutions.

Deneb Medical is a start-up dedicated to developing a robotic platform for applications in neurosurgery, CMF surgery, head and neck surgery, urology and general surgery.

X-COR Therapeutics, based in Allston, Massachusetts, is a medical device company focused on developing innovative CO2 removal devices for patients experiencing acute respiratory failure. Founded in 2017, the company has created a novel consumable hybrid cartridge that enables the removal of excess carbon dioxide from a patient's blood using ultra-low blood flows of less than 300 ml/min. This approach is less invasive and allows for easier placement by nursing staff, making the therapy more accessible and affordable compared to traditional extracorporeal devices, which typically require higher blood flow rates and specialized medical personnel. X-COR's technology is supported by a machine-learning-based control algorithm and is designed to integrate smoothly with existing medical infrastructure, enhancing its usability in clinical settings. The company gained recognition as a runner-up in the 2018 Harvard President’s Innovation Challenge and participated in the MedTech Innovator and MassChallenge cohorts that same year.

Paragate Medical is a company based in Nazareth Illit, Israel, specializing in the design and development of implantable devices aimed at providing continuous relief for patients suffering from congestive heart failure and fluid overload conditions related to heart and kidney failure. The company's innovative solutions address the clinical symptoms associated with these health issues, ultimately aiming to alleviate the associated healthcare burden for patients.

Impleo Medical is a developed a proprietary bulking agent therapy for Gastroesophageal Reflux Disease in medical devices

AuriGen Medical Limited, an electrophysiology and structural heart company, develops LAA implants to treat the stroke and arrhythmia risk associated with persistent atrial fibrillation. The company was founded in 2016 and is based in Dublin, Ireland.

Strados Labs, LLC is a medical technology company based in Philadelphia, Pennsylvania, that focuses on innovating respiratory health management through advanced biosensors and artificial intelligence. Founded in 2016, Strados Labs develops a wearable device that provides real-time insights into respiratory metrics such as breathing speed, sounds, and patterns. This device is equipped with a continuous breathing sensor that enables remote monitoring of patients with respiratory conditions like asthma and chronic obstructive pulmonary disease. By connecting the device to a mobile application, patients and healthcare providers can access critical respiratory data, facilitating informed decision-making and improved management of respiratory health.

TrueCath is a medical device company creating the next generation of peripheral IV auto-catheters. Truecath is of similar size, shape, and manufacturing cost to the currently used PIVC systems. It can also be placed with only one hand and is mostly independent of operator skill level. Importantly, Truecath will prevent the most common cause of missed first attempt PIVC placement, which is penetration through the back wall of the vessel and catheter failure. This key advantage will decrease the multitude of complications involved with PIVC placement, improve patient comfort and reduce healthcare costs. The company was founded in 2016 and is headquartered in Camarillo, California.

PercuSense is a development-stage company dedicated to advancing healthcare through innovative invasive medical devices that utilize physiological triggers for continuous monitoring. The company has developed a calibration-free electrochemical sensor capable of simultaneously measuring glucose, lactate, and oxygen levels. This technology provides patients with real-time and retrospective data on their metabolic health, facilitating better disease management and informed therapeutic decisions. By focusing on continuous multi-analyte monitoring, PercuSense aims to enhance patient outcomes and improve the overall understanding of metabolic health.

Deneb Medical is a start-up dedicated to developing a robotic platform for applications in neurosurgery, CMF surgery, head and neck surgery, urology and general surgery.

Ictero Medical is a medical devices company focused on developing innovative solutions for patients with gallstone disease. The company has created a minimally invasive gallbladder ablation tool that allows for the treatment of high-risk patients without the need for surgical removal of the gallbladder. This device can be utilized in interventional radiology suites and requires only minimal local anesthesia, thereby reducing the associated risks of traditional surgery. By offering a definitive treatment option, Ictero Medical aims to improve patient outcomes while minimizing complications related to gallbladder surgery.

PhotoniCare, Inc. is a medical device company founded in 2013 and based in Champaign, Illinois. The company develops advanced diagnostic tools aimed at improving the standard of care for patients with ear infections. Its primary product, the TOMi Scope, utilizes near-infrared light waves to provide three-dimensional views of the middle ear, allowing physicians to see beyond the eardrum. This innovative device leverages patented technology derived from bioengineering research at the University of Illinois at Urbana-Champaign, addressing the limitations of traditional otoscopes, which can only provide surface-level views. By enabling more accurate screening and diagnosis of ear diseases, PhotoniCare aims to enhance patient outcomes and streamline the diagnostic process for healthcare providers.

Darmiyan, Inc. is a company that specializes in the development of diagnostic software aimed at the early detection and monitoring of Alzheimer's disease and other neurodegenerative disorders. Based in San Francisco and founded in 2014, the company offers BrainSee, a Software as a Service platform that utilizes non-invasive brain MRI scans to produce detailed brain maps. This innovative tool quantifies neurodegeneration in individual brain voxels and generates a summary score reflecting brain health and the risk of cognitive decline. BrainSee operates using proprietary technology, referred to as The Virtual Microscope, which provides insights into brain cell distortion before clinical symptoms manifest. The algorithm has undergone successful third-party validation in the US and Canada, demonstrating its accuracy in predicting mild cognitive impairment. By leveraging advanced medical imaging and artificial intelligence, Darmiyan aims to enhance early diagnosis and intervention for patients with neurodegenerative diseases.

ODS Medical Inc. is a Montreal-based medical device company established in 2015, specializing in the design and manufacture of a proprietary Raman spectroscopy system for cancer detection. The company focuses on commercializing this advanced technology to enable real-time detection of tissue abnormalities across various clinical settings. By integrating innovative optical probes with sophisticated software powered by machine learning algorithms, ODS Medical aims to provide physicians with next-generation diagnostic tools. This approach enhances the sensitivity, specificity, and accuracy of medical diagnoses, ultimately empowering healthcare professionals to make critical decisions in real-time.

AtaCor Medical, Inc. is a medical device company based in San Clemente, California, focused on cardiac pacing and rhythm management. Founded in 2014, the company has developed the AtaCor EV Temporary Pacing System, an innovative implantable system that utilizes a parasternal approach to provide temporary pacing without the need for traditional leads or hardware attached to the heart. This system introduces a pacing lead into the extracardiac tissue located between the ribs and pericardium, allowing for quick and effective restoration of cardiac rhythm in patients. AtaCor Medical aims to enhance the delivery of temporary, interim, and permanent cardiac pacing solutions in critical situations.

GT Medical Technologies, Inc. is a medical device company based in Tempe, Arizona, focused on enhancing the treatment options for patients with brain tumors. Founded in 2017, the company has developed GammaTile, an innovative medical device that integrates a biocompatible collagen matrix with brachytherapy radiation seeds. This technology is designed to address the limitations of existing treatments for recurrent brain tumors, providing a conformable and bioresorbable solution that can potentially prevent disease progression and improve patient quality of life. GammaTile has received multiple patents and has shown promise in clinical trials, with significant improvements observed in patients treated at the Barrow Neurological Institute. This approach aims to revolutionize care for the estimated 176,000 individuals diagnosed with brain tumors annually in the United States.

Deton Corp. is a diagnostics technology company based in Pasadena, California, founded in 2011. It specializes in developing innovative solutions for measuring and controlling lower respiratory infections. The company's flagship product, the aerosol biopsy solution, captures aerosol droplets expelled during coughing, allowing for the extraction of genetic information from within the lungs. This technology enables the collection of samples from the lower respiratory tract, facilitating the diagnosis of infections and providing valuable insights into the growth of fungal and bacterial microbes. Through its advancements, Deton aims to enhance the understanding and treatment of lung diseases by delivering complete and timely lung health information.

Colabs is a medical device manufacturing company that focuses on developing an emergency airway and ventilation system. Its device specializes in airway management and ventilation during cardiac arrest. The company was founded in 2012 and headquartered in St, Morgan Hill, California.

Medable, Inc. operates a cloud-based platform that facilitates decentralized clinical trials, enabling healthcare providers, biopharma sponsors, and clinical research organizations to enhance trial design, recruitment, retention, and data quality. The platform integrates various digital tools and services, ensuring compliance with health regulations while improving patient access and experience. Key offerings include solutions for telemedicine, such as HIPAA-compliant video consultations and platforms for capturing clinical trial outcomes remotely. Medable's services support the creation of applications for mobile, desktop, and web use, addressing the needs of doctors, hospitals, and health technology companies. Founded in 2015 and headquartered in Palo Alto, California, Medable has been utilized in clinical trials across over 30 countries and 26 languages, contributing to more effective therapy delivery and patient outcomes.

Day Zero Diagnostics (DZD) is developing a new class of diagnostic that enables a physician to switch from broad spectrum antibiotic therapy to a targeted antibiotic in 5 hours rather than the 2-5 days that it typically takes today. Unlike other molecular diagnostics that can only detect a handful of specific targets, DZD uses the entire genomic sequence and our proprietary Keynome™ algorithm to identify a comprehensive range of bacterial pathogens and their resistance characteristics within hours.

Eximis Surgical, founded in 2014 and headquartered in Louisville, Colorado, specializes in developing innovative technology for laparoscopic surgery. The company has created a specimen removal device that enables surgeons to efficiently extract large specimens through small incisions. This device utilizes radio frequency (RF) energized cutting wires, which are temporarily held in a containment bag, allowing for quick and safe specimen removal. By integrating seamlessly into existing physician protocols, Eximis Surgical's technology significantly reduces the time required for specimen extraction, minimizes patient discomfort, and ensures safe surgical outcomes. Additionally, the device separates specimens into narrow strips, facilitating the creation of clean tissue segments for accurate pathology identification, thereby enhancing the overall effectiveness of minimally invasive surgery.

The Otricath™ introduces a new perspective on therapy delivery. The platform technology delivers cancer-fighting agents to solid tumors with unparalleled control, predictability, and safety for optimal therapeutic benefit and minimal systemic toxicity.

Innoblative Designs, Inc. is a medical device company based in Chicago, Illinois, with an additional office in Mansfield, Massachusetts. Founded in 2013, the company specializes in developing advanced electrosurgical devices, particularly focusing on radiofrequency ablation technology. One of its key innovations is the Sira™ device, a saline-assisted intraoperative radiofrequency ablation tool that employs bipolar current to create a controlled zone of ablation. Sira's unique design, featuring a saline microinfusion system, enhances contact with target tissue and is compatible with standard electrosurgical generators already utilized in operating rooms. This technology offers surgeons a new, effective option for intraoperative ablation of soft tissue, promoting ease of use and adoption in surgical practices.

GreenLight Medical, Inc. is a cloud-based platform that facilitates the procurement process for medical devices within hospitals. Founded in 2014 and headquartered in Nashville, Tennessee, the company offers a software-as-a-service tool designed to enhance the decision-making process regarding medical technology purchases. The platform serves as a collaborative space for hospitals, medical suppliers, and other stakeholders, enabling streamlined workflows and effective project management. By connecting all parties involved, GreenLight Medical promotes cost-effective and quality-conscious purchasing decisions. It manages the entire sales cycle, from the introduction of medical device companies to their approval and use in healthcare facilities, providing actionable data and insights to improve the procurement process.

Revolutionary Medical Devices, Inc. began June 2014 where it received critical acclaim at the Post-Graduate Assembly (PGA) for Anesthesiology. RMD has received worldwide recognition from Key Opinion Leaders in Anesthesia and its technologies are living up to their name, “Revolutionary”. The company’s mission is to utilize current clinical literature to drive the development of innovative technologies to optimize patient positioning during airway management and anesthesia. RMD develops airway management products to significantly improve anesthesiologist workload, O.R. turnover time, and easier patient intubation.

mOm Incubators Ltd. specializes in the development of electronically controlled inflatable infant incubators designed to reduce infant mortality rates, particularly among premature infants. Founded in 2014 and based in London, the company has created a collapsible incubator that provides thermoregulation comparable to traditional models. This innovative solution is versatile, catering to various environments, from rural areas in Africa to urgent neonatal transport in developed countries. mOm's incubators aim to create a safe and supportive environment for pre-term infants, addressing critical challenges faced in settings such as refugee camps, where conventional incubators may be impractical.

Arterys Inc. is a technology company specializing in medical imaging analytics, aiming to enhance patient care through innovative solutions. Founded in 2007 and headquartered in San Francisco, California, with additional offices in Calgary and Paris, Arterys offers a cloud-based, AI-powered platform that enables radiologists to visualize and quantify blood flow in the body. Its product lineup includes Cardio AI for cardiac imaging, Lung AI for lung analysis, Liver AI for liver diagnostics, and Chest/MSK AI for detecting various thoracic and musculoskeletal conditions. The platform is fully web-based and FDA-cleared, providing clinicians with tools for automatic and interactive reporting. Additionally, the Arterys PHI Service allows physicians to access patient data remotely, further supporting efficient medical practices.

Aqueduct Critical Care addresses the critical care problem of managing inter-cranial pressure. Its working prototypes demonstrate the ability to allow the patient to move, and minimize attention from nursing staff. Aqueduct Critical Care was founded in 2013 and is based in Bothell, Washington.

Nebula Industries is solving the problem of medical adhesive related injuries for those with fragile skin, particularly older people, using innovative approaches developed at MIT/Brigham and Women's Hospital.

Selio is a simple, effective and patent protected technology. The Selio prototype has been rigorously tested in the lab and in subsequent acute pre-clinical in vivo studies with very positive results.

PeriCor provides minimally invasive alternatives to infants, children and adults who require interventions including pacemakers, defibrillators or cardiac ablation procedures.

M&S Biotics, LLC is a healthcare technology company based in Scranton, Pennsylvania, established in 2014. It focuses on enhancing the efficiency, efficacy, and safety of surgical procedures through its innovative Biotic Integration system. This system utilizes radio frequency identification (RFID) technology and artificial intelligence to automate the counting of surgical items in real-time, thereby eliminating lengthy inventory protocols. Additionally, the company provides Biotic Insight, an analytics platform that offers valuable data regarding instrument utilization. By streamlining surgical processes, M&S Biotics aims to alleviate the financial pressures faced by hospitals and surgical facilities, enabling them to perform more surgeries annually and ultimately drive revenue growth.

Access Vascular, Inc. is a medical technology company based in Bedford, Massachusetts, founded in 2015. The company specializes in developing venous access devices utilizing innovative hydrogel materials to significantly reduce the accumulation of blood components that can lead to thrombosis, infections, and other complications associated with intravenous therapy. Their product line includes peripherally inserted central catheters (PICC), hemodialysis access devices, implantable ports, and drug delivery systems. By addressing common issues in venous access, Access Vascular aims to improve clinical outcomes, decrease healthcare costs, and enhance patient experiences by minimizing morbidity, shortening hospital stays, and reducing pain. The company's initial focus is on launching the HydroPICC, which promises superior performance compared to existing technologies.

OncoTAb, Inc., a North Carolina based startup, was co-founded by Mayo Clinic alumna Dr. Pinku Mukherjee, with a mission to improve the quality of cancer care by addressing unmet cancer diagnostic and therapeutic needs. The company’s first product, Agkura™ Personal Score, is a simple, non-invasive blood test offered as a supplement to mammography for women with dense breast tissue. Mammograms fail to detect cancer in 50% of women with high breast tissue density*, resulting in late stage diagnosis and mortality. The Agkura™ Personal Score shows a continuous trend of increasing values from benign disease through Breast Cancer Stages 1 to 4, with statistically significant increases prior to late stage breast cancer. Women with dense breast tissue can bi-annually monitor their personalized score in conjunction with annual mammograms. An increasing trend would indicate the need for additional imaging modalities and result in earlier stage diagnosis of breast cancer.

Voyager Biomedical, Inc. is committed to improving the lives of dialysis patients through the development of a novel vascular access device known as the ARK. The ARK has been designed to facilitate targeted needle placement and strengthen the vein by serving as a supportive exoskeleton. In addition, the ARK will increase patient comfort, and reduce stress and increase efficiency for caregivers, while benefiting the payer system by decreasing the surgeries necessary to enable long-term vascular access.

Nexeon MedSystems is a bioelectronics company developing active medical devices for the treatment of chronic medical conditions. The solutions we're developing are a unique blend of traditional device technologies such as electronics, software, mechanical engineering, and material science, as well as pharmaceuticals, protein chemistry, and cell biology.

NovaGray is focused on creating advanced companion diagnostic tests designed to enhance radiation therapy planning. The company develops biomarker-based tests that evaluate patients' sensitivity to radiation through a single blood sample. This approach allows healthcare practitioners to tailor treatment plans, including dosage and session sequencing, based on individual patient profiles. By personalizing standard treatments, NovaGray aims to improve patient outcomes while also reducing both complication and overall treatment costs.

Patientory, Inc. is a healthcare technology company based in Atlanta, Georgia, that focuses on personal healthcare solutions. Founded in 2015, Patientory provides a platform that allows patients to manage their medical records and chronic illnesses while enabling healthcare providers to connect with patients effectively. The company's solution utilizes a blockchain-enabled network to gather and analyze healthcare data, offering insights that empower individuals to take charge of their health. By facilitating secure access to and management of health information, Patientory enhances care coordination among doctors, care providers, and patients, ultimately aiming to improve health outcomes and reduce healthcare costs.