MedTech Innovator

Indago is a biotechnology company that creates the operating room of the future through smart surgical tools. For surgeons who struggle with cumbersome wires and outdated technology, they built ArthroFree, a fully wireless visualization platform with an attractive cost profile that integrates into existing OR workflows, allowing physicians to focus on patients and procedures, not their tools. The company was founded in 2015 and is headquartered in Cleveland, Ohio, United States.

Actionable, accessible, and affordable feedback system for preventive health maintenance.

ConKay Medical Systems is an early-stage medical device company focused on developing innovative solutions to address valvular regurgitation in patients suffering from progressive heart failure. The company's technology is centered around annular repair, which targets the primary cause of functional regurgitation while preserving the integrity of healthy leaflets. This approach aims to enhance the effectiveness of cardiovascular care, providing healthcare professionals with advanced tools to better manage this condition.

Digma Medical is a clinical stage medical device company established in 2013, focused on innovating treatments for Type-2 Diabetes and related metabolic syndromes, including NASH. The company is developing the DiaGone™, an endoscopic and disposable device that employs advanced laser technology to treat the duodenum without the need for an implant. The Duodenal Glycemic Control™ procedure, which lasts approximately 30 minutes, allows gastroenterologists to use the DiaGone™ to enhance the body's ability to regulate glucose levels. This approach aims to offer patients the potential for long-term remission from Type-2 Diabetes and other metabolic conditions, thereby improving their overall quality of life and health outcomes. Supported by prominent venture capital firms, Digma Medical is dedicated to advancing effective therapies for diabetes management.

Healthcare X.0 is an online healthcare platform that provides its clients with digitization solutions. The platform provides its clients with health, vascular, patient, onco, nephro, cardio, wound, tele, patient, and diabetic assist database solutions. Healthcare X.0 was launched in 2013 by and is based in Niedersachsen.

Tricog Health Services Pvt Limited, established in 2014 and headquartered in Bengaluru, India, specializes in cloud-connected ECG devices that facilitate the interpretation and analysis of electrocardiography (ECG) reports. The company addresses critical gaps in cardiac care, particularly in regions with limited access to diagnostic tools and trained personnel. Tricog's offerings include the InstaECG and VCardia applications, which enhance the speed and accuracy of cardiac monitoring. The company leverages artificial intelligence to provide real-time reporting and analysis of ECG results, enabling quicker diagnosis of cardiac events. This timely intervention is crucial, as survival rates for heart attack patients significantly improve with prompt treatment, yet many patients experience delays in diagnosis and care. Tricog Health aims to bridge these gaps, potentially saving millions of lives by ensuring that primary care clinics are equipped with affordable and efficient ECG solutions. With a presence in Singapore, Malaysia, and China, Tricog is positioned to expand its impact in the global healthcare landscape.

CloudMedx Inc. is a software development company based in Palo Alto, California, that specializes in artificial intelligence solutions for the healthcare sector. Founded in 2014, the company focuses on extracting key clinical concepts from electronic health records to provide actionable insights that enhance clinical operations, documentation, and patient care. Its platform transforms disparate healthcare data into a cohesive view that supports better clinical, treatment, and diagnostic outcomes. By integrating with existing systems, CloudMedx aims to facilitate collaboration among healthcare providers, payers, and patients. The company offers tools for patient engagement, risk stratification, and timely notifications for care needs, serving a diverse clientele that includes managed care organizations, accountable care organizations, and various healthcare facilities. The mission of CloudMedx is driven by a commitment to improve healthcare delivery, stemming from personal experiences related to misdiagnosis and the inefficiencies within the healthcare system.

Discure Technologies is focused on creating a minimally invasive, implantable bioelectronic device aimed at treating degenerative disc disease (DDD). This innovative device employs a novel bioelectric technique that addresses the root cause of DDD, allowing physicians to alleviate pain and restore normal disc function in patients. By promoting healing of the affected discs, Discure seeks to improve the quality of life for individuals suffering from this condition.

Endoluxe, Inc. manufactures a portable device to perform endoscopic procedures. The company’s EVS system offers features, such as wireless display, HD camera, voice activation, and auto image stabilization with applications in Urology, Gynecology, Pulmonology, and Orthopedics. Endoluxe, Inc. was incorporated in 2013 and is based in Dunwoody, Georgia.

CARI Health is a digital health company based in San Diego, California, that specializes in the development of remote medication monitors. Founded in 2015 and incorporated in 2021, the company creates wireless sensors that patients wear on their skin. These sensors continuously transmit real-time data about medication levels to the cloud, allowing clinicians to safely prescribe, dose, and monitor adherence to critical medications. By providing this innovative solution, CARI Health aims to enhance patient care and improve health outcomes through better medication management.

Leadoptik is a California-based company operating in stealth mode, focused on developing advanced miniature imaging technology for minimally invasive medical procedures. This innovative technology enhances surgeons' ability to view small objects with improved clarity compared to existing imaging systems, offering 3D navigation capabilities and high-resolution imaging. By facilitating the early detection of cancer in patients, Leadoptik aims to significantly improve surgical outcomes and patient care.

Anumana is an AI-driven company that develops ECG algorithms enabling early disease diagnosis and intervention. Anumana harnesses industry-leading AI and translational science to decode the electrocardiogram (ECG) – like a deep predictive tool and biomarker of disease, empowering care providers to help patients early.

Gradient Denervation Technologies develops a endovascular catheter-based medical device to treat pulmonary hypertension. Its medical device aims at reducing pulmonary vascular resistance and improving cardiovascular hemodynamics. The company was incorporated in 2019 and is based in Paris, France.

Operator of a microbiology research company intended to democratize molecular biology by moving complex molecular biology tools out of highly skilled laboratories to non-laboratory settings. The company's innovative enzymatic approach to nucleic acid extraction offers sample preparation suitable for PCR (polymerase chain reaction) analysis, enabling clients to create the next generation of person-portable diagnostic devices for the management of infectious diseases and other personalized medicine applications.

Phiex Technologies on-demand, interactive materials for efficient and cost-effective medical device manufacturing, food safety and packaging, and innovations for pathogens.

LiveMetric is a medical device company developing non-invasive sensing and deep data analytics solutions. The company transforming the care and condition-management of hypertension and cardiovascular diseases. Using their own proprietary, non-invasive arterial pressure technology, they provide a wearable, non-invasive medical device which enables AI-augmented care and condition management treatment services management. LiveMetric delivers high fidelity arterial pressure waveforms and detailed activity mapping of the single user at any time. They seek to empower individuals, payors, self-insured employers and healthcare providers with an accurate, fact-based, personalized care platform that has the potential for improving the care and lives of over 1 Billion people worldwide who suffer from these conditions. The company's goal is to provide prescribed patients, caregivers, and payors with pertinent data and detailed daily activity mapping.

DermaSensor, Inc. develops a hand-held device that uses artificial intelligence to evaluate skin lesions for cancer. It offers DermaSensor, a device that allows physicians and consumers to perform skin checks in physician offices and patient homes. The company’s device is also used for lesion identification, scanning, photon scattering, and algorithmic analysis. DermaSensor, Inc. was founded in 2009 and is based in Miami, Florida.

Augment Health is a medical device company in the southeast United States. Augment Health is focused on improving patient quality of life and care outcomes, initially focused on the population of catheter users with limited bladder sensation. They have developed a bladder management system that lets patients know when they need to go.

SafeBeat Rx replaces a hospitalization with a take-home kit that combines FDA-approved wearables with life-saving ECG software that expands access to proven heart therapies.

Garwood Medical Devices, LLC develops and manufactures medical devices related to infection, perio-prosthetic, and wound healing. It offers BioPrax, a minimally invasive device that targets and eliminates biofilm infections on prosthetic knee implants during early intervention procedures. Garwood Medical Devices, LLC was formerly known as Enermed, LLC and changed its name to Garwood Medical Devices, LLC in December 2015. Garwood Medical Devices, LLC was incorporated in 2014 and is based in Buffalo, New York.

TrackX Technology develops a tracking technology that provides real-time virtual live fluoroscopy. It focuses on creating profound procedurally driven imaging solutions that provide priceless benefits to the surgeon, hospital, and entire operating room.

Robotic Hospital Nutrition Management Systems

52 North Health is focused on enhancing healthcare for cancer patients, specifically those undergoing chemotherapy, by providing a portable and easy-to-use medical device. This device employs artificial intelligence to assess the risk of neutropenic sepsis, a serious and potentially fatal side effect of chemotherapy. Through a finger prick blood test and a corresponding digital platform, the device measures a patient's neutrophil count and C-reactive protein (CRP) levels at home. This functionality allows for timely identification of patients at risk of sepsis, thereby improving their safety and quality of life. By facilitating rapid management of their condition, 52 North Health offers a reliable and cost-effective solution for cancer patients.

CardiaCare is focused on developing a wearable medical device aimed at the non-invasive treatment and monitoring of atrial fibrillation (AFib) in patients. Utilizing a closed-loop approach and machine learning algorithms, the device applies personalized peripheral neuromodulation to elicit a cardiovascular antiarrhythmic response. This innovative technology enables users to effectively reduce the burden of atrial fibrillation and mitigate its precursors, such as premature atrial contractions. As a result, patients can experience rapid clinical and symptomatic relief while managing their condition from the comfort of their homes.

Endiatx is a medical device manufacturing company that specializes in developing a series of pill-sized robots to perform remote diagnosis. Its unique propulsion system which allows our pill robots to actively navigate the entire length of the GI tract is approximately 30 minutes with real-time video control. It was founded in 2019 and headquartered in Redwood City, California.

Bright Uro is an early-stage medical technology company. It is building the next generation of diagnostic devices for Urology. Utilizing advanced hardware, software, and data science can unlock new data streams and offer actionable insight for clinicians.

Flosonics is a medical device company that focuses on developing non-invasive sensors to improve the management of critically ill patients. Flosonics's flagship smart-bandage product, the FloPatch, addresses unmet clinical needs of critically ill patients and the physicians, nurses, and paramedics who care for them in the ambulance, emergency department, operating room, and intensive care unit.

Forest Devices, Inc. is a medical device company based in Pittsburgh, Pennsylvania, with an additional office in Canada. Founded in 2014, the company focuses on developing innovative solutions for stroke detection. Its flagship product, AlphaStroke, is a non-invasive, AI-powered device designed for medical personnel to identify strokes in various environments, even before advanced imaging techniques like CT or MRI are available. This portable and durable device can detect both ischemic and hemorrhagic strokes, enabling practitioners to triage patients effectively and improve treatment outcomes. By streamlining the decision-making process in stroke management, AlphaStroke aims to reduce delays in critical care and enhance the overall frequency of stroke treatments.

OncoRes Medical Pty Ltd is an early-stage medical device company based in Nedlands, Australia, founded in 2014. The company specializes in developing a patented imaging technology that provides surgeons with real-time, micro-scale images of tissue stiffness and elasticity during breast cancer surgeries. This innovative tool integrates optical coherence tomography to enhance surgical accuracy, aiding in the differentiation between tumor and healthy tissue. OncoRes collaborates with leading researchers at the University of Western Australia and the Harry Perkins Institute of Medical Research, as well as breast cancer surgeons in the Western Australian public health system. With support from the Medical Research Commercialisation Fund, OncoRes Medical aims to improve clinical applications by enabling precise intraoperative assessments of tissue microstructure, ultimately striving to transform the standard of care in breast cancer treatment.

Bardy Diagnostics, Inc. is a medical device company that specializes in the development and manufacturing of cardiac monitoring solutions, primarily focused on arrhythmia detection. Its flagship product, the Carnation Ambulatory Monitor (CAM), is a lightweight, discreet cardiac patch that can be worn comfortably for up to seven days, even during physical activities like exercise or showering. The CAM is designed with a unique hourglass shape to enhance comfort, particularly for female patients. Complementing the monitor is the BDxCONNECT patient management system, which allows healthcare providers to create and manage patient reports efficiently. By utilizing innovative P-wave centric ECG detection technology, Bardy Diagnostics aims to improve clinical management and outcomes for patients and their physicians. Founded in 2013, the company is headquartered in Seattle, Washington, with additional offices in Houston, Texas, and New Providence, New Jersey.

Subtle Medical, Inc., a healthcare technology company, develops medical imaging software for clinical imaging centers and hospitals. Its product includes SubtleMR, an artificial intelligence-based image processing software that reduces image noise and increases image sharpness for non-contrast enhanced magnetic resonance imaging (MRI). It enables to reduce cost, imaging time, and radiation/contrast dose. The company was founded in 2017 and is based in Menlo Park, California.

EndObetes is a medical device company that develops an endoscopically food delivery solution for treating obesity and diabetes. The company's device shunts food directly from the esophagus to the intestine, bypassing the stomach and duodenum, much like gastric bypass surgery, enabling people to get access to a durable, safe and effective non-surgical treatment for obesity and diabetes. It was founded in 2015 and is based in New York, New York.

HEPTA Medical develops a sensor, embedded into a bronchoscopic or percutaneous ablation catheter, which provides temperature-based feedback. This enables real-time dosing to precisely target and ablates pulmonary nodules, the precursor of lung cancer, without the need for surgery or radiation.

CoapTech, Inc. is a medical device company based in Baltimore, Maryland, founded in 2016. It specializes in developing ultrasound-based solutions for feeding tube placement, primarily through its Point-of-care Ultrasound Magnet Aligned (PUMA-G) System. This innovative system enhances safety by using ultrasound visualization to guide the insertion of gastrostomy tubes, thereby eliminating risks associated with traditional methods such as PEG blind sticks, endoscope reprocessing, and fluoroscopy. CoapTech’s technology, known as Coaptive Ultrasound, utilizes strong rare-earth magnets for device placement and low-cost ultrasound for real-time visual feedback. This approach allows non-surgical providers to perform the percutaneous ultrasound gastrostomy (PUG) procedure efficiently and safely, improving patient care delivery while reducing healthcare costs. The company aims to disrupt multiple medical procedures by providing simpler, safer, and more affordable alternatives, focusing on enhancing access to quality medical services globally.

Orbit Genomics applies its proprietary OrbiSeq technology platform to aid in diagnosing and ultimately preventing complex diseases.

CloudCath is a company that specializes in developing a remote monitoring platform for peritoneal dialysis patients. Their innovative system utilizes sensor-enabled technology to provide continuous monitoring, allowing for early detection of complications associated with catheter-based treatments. By leveraging Internet of Things (IoT) capabilities, CloudCath's platform enables healthcare providers to remotely oversee patients during their home treatment, significantly reducing the frequency of in-person visits. This approach not only enhances patient safety but also improves the overall management of care for individuals undergoing peritoneal dialysis, ultimately promoting better health outcomes.

ThermopeutiX is a privately held company that offers imaginative, innovative and economical solutions to unmet medical needs.

Previvo is a medical device company focused on preventing genetic diseases through its innovative technology that enhances pre-implantation genetic testing. By offering a more natural and healthier alternative to traditional in vitro fertilization and embryo collection methods, Previvo aims to empower women and couples undergoing assisted reproduction. Its patent-pending device is designed to facilitate pre-implantation genetic diagnosis and screening, helping to ensure healthier outcomes for prospective parents and their future children.

Olfactomics is a Finnish university-based spinoff company developing a novel technology for surgical tissue assessment. They focus on improving breast-concerving lumpectomies where residual tumor continues to be an issue. Realtime tissue analysis allows the surgeon to remove the whole tumor in one operation and minimize the resection of healthy tissues.

Moving Analytics. is a tele-health company dedicated to helping people thrive after heart disease. Our flagship product is Movn a virtual cardiac rehabilitation program that leverages evidence based guidelines, behavioral science, remote monitoring and personalized coaching to help patients recover to full health after a cardiac event. Movn is currently used by the Veterans Affairs Medical Center, Highmark Health Plan, Kaiser Permanente Northwest and many more health systems across the US.

Bone Health Technologies, Inc. is focused on creating innovative medical devices to combat low bone mass conditions such as osteopenia and osteoporosis. The company's flagship product, OsteoBoost, is a wearable device designed for the lower back that utilizes whole-body vibration technology to deliver gentle mechanical stimulation. This stimulation mimics the effects of weight-bearing exercise, promoting bone health by activating stem cells to strengthen bone density. Founded in 2018 and headquartered in San Francisco, California, Bone Health Technologies aims to provide a safe and effective non-drug intervention for individuals at risk of bone mass deterioration.

Koya Medical, Inc. is a company based in Oakland, California, founded in 2018. It focuses on developing a connected wearable platform designed to address the significant unmet needs in the treatment of cancer-related chronic lymphedema and venous diseases. The technology aims to provide a drug-free solution for patients suffering from these conditions, enhancing their quality of life through innovative medical devices.

Patchd Inc is a healthcare technology company based in San Francisco, California, founded in 2017. The company specializes in developing a wearable device designed to predict sepsis in outpatient settings. Its wireless patch continuously collects vital sign data, enabling healthcare providers to monitor patients effectively. By employing artificial intelligence algorithms, Patchd's technology facilitates the early detection of life-threatening conditions, particularly when used by hospitals for newly admitted patients. This innovative approach aims to enhance patient care and improve outcomes in post-acute care scenarios.

toSense is focused on rapidly bringing devices to the market that address real-world medical issues. toSense’s solutions include both hardware (custom sensors) and software (servers), along with wireless solutions (gateways) that connect these components. Our core focus is the CoVa Sensor and its unique hardware and algorithms. Third-party software systems can integrate with this novel component using our gateways and web services.

Pristine Surgical LLC, founded in 2011 and based in Manchester, New Hampshire, has developed a groundbreaking single-use digital imaging platform tailored for surgical and diagnostic rigid endoscopic procedures. The company specializes in single-use digital arthroscopes and laparoscopes that come in a completely sterile kit. By integrating high-definition digital imaging, advanced LED lighting, artificial intelligence, and cloud-based software, Pristine Surgical aims to enhance the efficiency and safety of over 23 million procedures annually. The platform not only improves the surgical experience for patients and healthcare providers but also addresses key concerns such as cost reduction, risk mitigation, and the elimination of cross-contamination associated with reprocessing instruments. Through its innovative technology, Pristine Surgical strives to streamline the entire surgical episode, ultimately improving communication and satisfaction among surgeons and healthcare facilities.

HD Medical Group Pty Ltd. designs and develops innovative medical products aimed at the screening and detection of cardiac conditions. The company's primary offerings include the ViScope, an electronic stethoscope featuring a visual display for auscultation, and the ViScope MD, which integrates a phonocardiogram visual display along with a murmur indicator. These products are distributed through various channels, enhancing accessibility for healthcare professionals. Founded in 2005 and headquartered in Melbourne, Australia, HD Medical also maintains additional offices in Sunnyvale, California; St. Leonards, Australia; and Chennai, India. The company is recognized as a global leader in the management of cardiovascular disease, focusing on enabling evidence-based patient diagnosis.

Forest Devices, Inc. is a medical device company based in Pittsburgh, Pennsylvania, with an additional office in Canada. Founded in 2014, the company focuses on developing innovative solutions for stroke detection. Its flagship product, AlphaStroke, is a non-invasive, AI-powered device designed for medical personnel to identify strokes in various environments, even before advanced imaging techniques like CT or MRI are available. This portable and durable device can detect both ischemic and hemorrhagic strokes, enabling practitioners to triage patients effectively and improve treatment outcomes. By streamlining the decision-making process in stroke management, AlphaStroke aims to reduce delays in critical care and enhance the overall frequency of stroke treatments.

Respirix, Inc. is a medical technology company based in San Francisco, California, specializing in the development of precise analysis sensors for monitoring breath exhalation and cardiogenic oscillations. Founded in 2015, Respirix focuses on creating hardware and software solutions that provide insights into cardiac health, particularly through non-invasive monitoring of the pulmonary vasculature. Its product pipeline addresses various applications, including at-home monitoring and critical care, specifically targeting conditions such as heart failure and hemodynamics. The company's innovative approach integrates digital health tools to enhance the understanding and management of cardiac conditions.

AltraTech Limited, established in 2013 and located in Shannon, Ireland, specializes in the design of biosensors and semiconductor chips aimed at DNA testing for food traceability in the agricultural sector. The company has developed a portable device that enhances molecular detection of viral DNA and RNA using advanced enrichment and semiconductor techniques. This innovation achieves the sensitivity and specificity comparable to traditional PCR methods, allowing for rapid and accurate measurement of viral samples. Through these technologies, AltraTech contributes to improving food safety and quality in the agri-business industry.

Conavi Medical is a healthcare company focused on providing image guidance technologies for minimally invasive cardiovascular procedures.

PhotoniCare, Inc. is a medical device company founded in 2013 and based in Champaign, Illinois. The company develops advanced diagnostic tools aimed at improving the standard of care for patients with ear infections. Its primary product, the TOMi Scope, utilizes near-infrared light waves to provide three-dimensional views of the middle ear, allowing physicians to see beyond the eardrum. This innovative device leverages patented technology derived from bioengineering research at the University of Illinois at Urbana-Champaign, addressing the limitations of traditional otoscopes, which can only provide surface-level views. By enabling more accurate screening and diagnosis of ear diseases, PhotoniCare aims to enhance patient outcomes and streamline the diagnostic process for healthcare providers.

Darmiyan, Inc. is a company that specializes in the development of diagnostic software aimed at the early detection and monitoring of Alzheimer's disease and other neurodegenerative disorders. Based in San Francisco and founded in 2014, the company offers BrainSee, a Software as a Service platform that utilizes non-invasive brain MRI scans to produce detailed brain maps. This innovative tool quantifies neurodegeneration in individual brain voxels and generates a summary score reflecting brain health and the risk of cognitive decline. BrainSee operates using proprietary technology, referred to as The Virtual Microscope, which provides insights into brain cell distortion before clinical symptoms manifest. The algorithm has undergone successful third-party validation in the US and Canada, demonstrating its accuracy in predicting mild cognitive impairment. By leveraging advanced medical imaging and artificial intelligence, Darmiyan aims to enhance early diagnosis and intervention for patients with neurodegenerative diseases.

CU-BX provides high-accuracy measurements of driver health parameters, fatigue, stress, and comfort. Our patented technology maintains high-level accuracy across all road and lighting conditions and is agnostic to clothing and other accessories such as masks, sunglasses, headwear, etc. CU-BX works closely with all key automotive players (OEMs, Tier-1 and Tier-2 manufacturers) on providing driver monitoring systems (DMS) as well as aftermarket solutions. See our 1-pager here: https://www.dropbox.com/s/a0bp4dmmcwlwoe0/CU-BX_Automotive_OnePager.pdf?dl=0

Strados Labs, LLC is a medical technology company based in Philadelphia, Pennsylvania, that focuses on innovating respiratory health management through advanced biosensors and artificial intelligence. Founded in 2016, Strados Labs develops a wearable device that provides real-time insights into respiratory metrics such as breathing speed, sounds, and patterns. This device is equipped with a continuous breathing sensor that enables remote monitoring of patients with respiratory conditions like asthma and chronic obstructive pulmonary disease. By connecting the device to a mobile application, patients and healthcare providers can access critical respiratory data, facilitating informed decision-making and improved management of respiratory health.

PercuSense is a development-stage company dedicated to advancing healthcare through innovative invasive medical devices that utilize physiological triggers for continuous monitoring. The company has developed a calibration-free electrochemical sensor capable of simultaneously measuring glucose, lactate, and oxygen levels. This technology provides patients with real-time and retrospective data on their metabolic health, facilitating better disease management and informed therapeutic decisions. By focusing on continuous multi-analyte monitoring, PercuSense aims to enhance patient outcomes and improve the overall understanding of metabolic health.

Tasso, Inc. is a healthcare company based in Seattle, Washington, that specializes in the development of clinical-grade blood sample collection devices. Founded in 2012, Tasso has created innovative self-sampling devices that allow patients to collect their own blood at home with ease and convenience. These disposable devices are designed for user-friendliness, enabling individuals to obtain blood samples painlessly and securely. After collection, patients can mail the samples directly to qualified laboratories for analysis. Tasso's approach prioritizes patient comfort and privacy, fundamentally transforming the traditional blood collection process.

Ictero Medical is a medical devices company focused on developing innovative solutions for patients with gallstone disease. The company has created a minimally invasive gallbladder ablation tool that allows for the treatment of high-risk patients without the need for surgical removal of the gallbladder. This device can be utilized in interventional radiology suites and requires only minimal local anesthesia, thereby reducing the associated risks of traditional surgery. By offering a definitive treatment option, Ictero Medical aims to improve patient outcomes while minimizing complications related to gallbladder surgery.

Colabs is a medical device manufacturing company that focuses on developing an emergency airway and ventilation system. Its device specializes in airway management and ventilation during cardiac arrest. The company was founded in 2012 and headquartered in St, Morgan Hill, California.

X-COR Therapeutics, based in Allston, Massachusetts, is a medical device company focused on developing innovative CO2 removal devices for patients experiencing acute respiratory failure. Founded in 2017, the company has created a novel consumable hybrid cartridge that enables the removal of excess carbon dioxide from a patient's blood using ultra-low blood flows of less than 300 ml/min. This approach is less invasive and allows for easier placement by nursing staff, making the therapy more accessible and affordable compared to traditional extracorporeal devices, which typically require higher blood flow rates and specialized medical personnel. X-COR's technology is supported by a machine-learning-based control algorithm and is designed to integrate smoothly with existing medical infrastructure, enhancing its usability in clinical settings. The company gained recognition as a runner-up in the 2018 Harvard President’s Innovation Challenge and participated in the MedTech Innovator and MassChallenge cohorts that same year.

Spire, Inc., also known as Spire Health, develops health-tracking devices and remote patient monitoring solutions aimed at managing respiratory chronic diseases. Founded in 2013 and based in San Francisco, the company specializes in continuous respiration sensing and offers ambulatory monitoring services. Its technology includes an activity tracker that monitors physical movement, breathing patterns, and sleep, providing insights into inhalation and exhalation times, apneic events, and daily activities. Spire Health's solutions cater to various health conditions, including chronic obstructive pulmonary disease, congestive heart failure, asthma, sleep disorders, and anxiety. By leveraging advanced algorithms and sensors, Spire Health aims to empower patients and healthcare providers with actionable data to improve health outcomes and overall well-being.

Deton Corp. is a diagnostics technology company based in Pasadena, California, founded in 2011. It specializes in developing innovative solutions for measuring and controlling lower respiratory infections. The company's flagship product, the aerosol biopsy solution, captures aerosol droplets expelled during coughing, allowing for the extraction of genetic information from within the lungs. This technology enables the collection of samples from the lower respiratory tract, facilitating the diagnosis of infections and providing valuable insights into the growth of fungal and bacterial microbes. Through its advancements, Deton aims to enhance the understanding and treatment of lung diseases by delivering complete and timely lung health information.

ODS Medical Inc. is a Montreal-based medical device company established in 2015, specializing in the design and manufacture of a proprietary Raman spectroscopy system for cancer detection. The company focuses on commercializing this advanced technology to enable real-time detection of tissue abnormalities across various clinical settings. By integrating innovative optical probes with sophisticated software powered by machine learning algorithms, ODS Medical aims to provide physicians with next-generation diagnostic tools. This approach enhances the sensitivity, specificity, and accuracy of medical diagnoses, ultimately empowering healthcare professionals to make critical decisions in real-time.

Soundbite Medical Solutions Inc. is a cardiovascular medical technology company based in Montreal, Canada, specializing in the development and commercialization of innovative medical devices. Founded in 2013, the company focuses on creating a proprietary wire-based device and generator console that utilizes shockwave energy to treat chronic total occlusions (CTOs) within the cardiovascular system. This technology is designed to enhance vessel preparation for patients suffering from peripheral artery disease (PAD) and coronary artery disease (CAD), which collectively impact over 20 million individuals in the United States. Soundbite Medical Solutions aims to improve treatment outcomes for these patients through its advanced therapeutic solutions.

Day Zero Diagnostics (DZD) is developing a new class of diagnostic that enables a physician to switch from broad spectrum antibiotic therapy to a targeted antibiotic in 5 hours rather than the 2-5 days that it typically takes today. Unlike other molecular diagnostics that can only detect a handful of specific targets, DZD uses the entire genomic sequence and our proprietary Keynome™ algorithm to identify a comprehensive range of bacterial pathogens and their resistance characteristics within hours.

Day Zero Diagnostics (DZD) is developing a new class of diagnostic that enables a physician to switch from broad spectrum antibiotic therapy to a targeted antibiotic in 5 hours rather than the 2-5 days that it typically takes today. Unlike other molecular diagnostics that can only detect a handful of specific targets, DZD uses the entire genomic sequence and our proprietary Keynome™ algorithm to identify a comprehensive range of bacterial pathogens and their resistance characteristics within hours.

M&S Biotics, LLC is a healthcare technology company based in Scranton, Pennsylvania, established in 2014. It focuses on enhancing the efficiency, efficacy, and safety of surgical procedures through its innovative Biotic Integration system. This system utilizes radio frequency identification (RFID) technology and artificial intelligence to automate the counting of surgical items in real-time, thereby eliminating lengthy inventory protocols. Additionally, the company provides Biotic Insight, an analytics platform that offers valuable data regarding instrument utilization. By streamlining surgical processes, M&S Biotics aims to alleviate the financial pressures faced by hospitals and surgical facilities, enabling them to perform more surgeries annually and ultimately drive revenue growth.

NovaGray is focused on creating advanced companion diagnostic tests designed to enhance radiation therapy planning. The company develops biomarker-based tests that evaluate patients' sensitivity to radiation through a single blood sample. This approach allows healthcare practitioners to tailor treatment plans, including dosage and session sequencing, based on individual patient profiles. By personalizing standard treatments, NovaGray aims to improve patient outcomes while also reducing both complication and overall treatment costs.

Revolutionary Medical Devices, Inc. began June 2014 where it received critical acclaim at the Post-Graduate Assembly (PGA) for Anesthesiology. RMD has received worldwide recognition from Key Opinion Leaders in Anesthesia and its technologies are living up to their name, “Revolutionary”. The company’s mission is to utilize current clinical literature to drive the development of innovative technologies to optimize patient positioning during airway management and anesthesia. RMD develops airway management products to significantly improve anesthesiologist workload, O.R. turnover time, and easier patient intubation.

GreenLight Medical, Inc. is a cloud-based platform that facilitates the procurement process for medical devices within hospitals. Founded in 2014 and headquartered in Nashville, Tennessee, the company offers a software-as-a-service tool designed to enhance the decision-making process regarding medical technology purchases. The platform serves as a collaborative space for hospitals, medical suppliers, and other stakeholders, enabling streamlined workflows and effective project management. By connecting all parties involved, GreenLight Medical promotes cost-effective and quality-conscious purchasing decisions. It manages the entire sales cycle, from the introduction of medical device companies to their approval and use in healthcare facilities, providing actionable data and insights to improve the procurement process.

Also modify BD: Enspectra Health, Inc. develops a system to image live cellular anatomy. Its system images beneath the skin and displays images in real-time. Enspectra Health, Inc. was formerly known as Zebra Medical Technologies. The company was incorporated in 2012 and is based in Mountain View, California.

AVA Health Technologies is building a disruptive software platform that addresses challenges in pediatric care for children with acute, chronic, and rare conditions Our vision is to fill the gap in funding and focus in dedicated pediatric research and to provide a collaborative ecosystem for care that can facilitate discovery of new cures.

Advanced Prenatal Therapeutics (APT) is developing a novel therapeutic device for treating preeclampsia by specifically removing harmful substances from the mother’s blood.

Synotrac is a novel, patent pending sensor technology that detects infection in vivo and alerts the patient and their physician in real time. The device quickly analyzes the body's immune response to give a dynamic picture of the joint's healing process, which enables detection of infection significantly earlier than other methods.

PneuMotion provides continuous respiratory rate monitoring and obstructive apnea detection. PneuMotion seamlessly integrates into a hospital's existing network and allows mobile respiratory monitoring and EHR data collection. Ultra-low cost sensor technology makes this a cost-effective solution for opioid safety.

Genetesis LLC is a medical technology company focused on enhancing the diagnosis and management of cardiac conditions, specifically myocardial ischemia and coronary artery disease. Founded in 2013 and based in Mason, Ohio, Genetesis develops non-invasive biomagnetic imaging solutions, notably the Genetesis CardioFlux system. This advanced mapping technology allows for the detection and characterization of cardiac rhythm disorders by visualizing the heart's electrical currents in 3D. The company also utilizes the Faraday Analytical Cloud, a HIPAA-compliant platform that supports data management and workflow for the CardioFlux Magnetocardiograph (MCG). This innovative approach combines biomagnetic imaging with machine learning capabilities, aiming to improve patient health outcomes without exposing patients to radiation or requiring exercise during the procedure.

Nanowear, Inc. specializes in developing textile-based nanosensor technology designed for wireless and real-time electrophysiological monitoring. The company offers products like SimplECG, a remote cardiac monitoring undergarment, and SimpleSense, which focuses on monitoring and managing congestive heart failure. These garments capture multi-channel electrocardiogram (ECG), heart rate, and respiratory rate data, which is transmitted to a web-based portal for physician review via a mobile application. Nanowear's technology is versatile, finding applications in cardiac, neurological, industrial safety, government, sports medicine, and performance diagnostics. Founded in 2014, the company is headquartered in Brooklyn, New York, with a research and development facility located in University Park, Pennsylvania.

Avenda Health Inc. is focused on developing a minimally invasive treatment for prostate cancer through its artificial intelligence-based focal laser ablation system. This innovative technology includes a fiber-optic laser and a disposable sensor, which work together with a feedback control system to provide precise treatments. The system integrates prostate images and biopsies using MRI-ultrasound fusion for guidance, allowing procedures to be performed under local anesthesia. Avenda Health aims to deliver safe, effective, and cost-efficient alternatives for patients, enhancing their quality of life while undergoing outpatient treatment. Founded in 2017, the company is headquartered in Santa Monica, California.

Abreos Biosciences develops lateral flow assays that measure the activity of high-value biologics. Its simple devices can be used for quality assurance, pharmacokinetic monitoring, and authentication in field, forensic, or point of care settings. We deliver value by enhancing brand protection, improving patients’ outcomes, and enabling rapid authentication for counterfeit prevention and end-user confidence. The company was founded in 2013 and headquartered in San Diego, California.

PeriCor provides minimally invasive alternatives to infants, children and adults who require interventions including pacemakers, defibrillators or cardiac ablation procedures.

Centerline Biomedical, Inc. is a Cleveland-based company founded in 2014, focused on developing advanced navigation systems for interventional vascular procedures. The company specializes in a non-x-ray based, three-dimensional GPS surgical navigation technology that enhances the precision and outcomes of endovascular procedures while significantly reducing radiation exposure for both patients and healthcare providers. This innovative system assists surgeons in accurately navigating catheters and guide wires through the complex three-dimensional anatomy of patients with vascular diseases, ultimately enabling safer and more effective image-guided surgeries. The technology is rooted in research and development from the Cleveland Clinic, highlighting its commitment to improving surgical practices in the medical field.

Harbor MedTech, Inc. is a regenerative medicine company focused on developing and commercializing tissue regeneration products. Founded in 2010 and based in Irvine, California, the company offers a range of innovative solutions including Architect, an extracellular collagen matrix designed for managing various types of wounds such as diabetic ulcers, pressure sores, and surgical wounds. Additionally, Harbor MedTech provides NeuvoCell, a wound therapy specifically for chronic wounds, alongside products aimed at hernia and joint repair, orthopedic soft tissue repair, breast reconstruction, and urogynecological repair. Utilizing its BriDGE platform, the company is expanding its product pipeline to address needs in dermatology, general surgery, and plastic surgery. Harbor MedTech also maintains a strategic partnership with Edwards Lifesciences to enhance its offerings in the market.

HemaFlo Therapeutics, Inc. is an early stage company founded to commercialize a novel new device for the treatment of acute kidney injury and other ischemic conditions. The device is a very dilute solution of drag-reducing polymer (DRP) that is simply delivered intravenously to patients. Drag-reducing polymers have been studied in animals since the mid-1970’s and have shown dramatic benefits in disease models such as heart attack, hemorrhagic shock, diabetes, and atherosclerosis. The work has received little attention because the mechanism of action was unknown until just recently. HemaFlo Therapeutics has shown that drag-reducing polymers can be used to treat a very common and deadly condition that has a very attractive commercialization pathway. Acute kidney injury has no effective treatment and there are as many new cases in the US each year as for heart attacks, strokes, and cancer combined! Acute kidney injury is not widely perceived to be a serious problem because most cases occur in the hospital as a consequence of other diseases or procedures, resolve in a week or two, and the deaths are coded as heart failure (loss of regulation of electrolytes), respiratory failure (loss of regulation of fluids), or sepsis.

OncoTAb, Inc., a North Carolina based startup, was co-founded by Mayo Clinic alumna Dr. Pinku Mukherjee, with a mission to improve the quality of cancer care by addressing unmet cancer diagnostic and therapeutic needs. The company’s first product, Agkura™ Personal Score, is a simple, non-invasive blood test offered as a supplement to mammography for women with dense breast tissue. Mammograms fail to detect cancer in 50% of women with high breast tissue density*, resulting in late stage diagnosis and mortality. The Agkura™ Personal Score shows a continuous trend of increasing values from benign disease through Breast Cancer Stages 1 to 4, with statistically significant increases prior to late stage breast cancer. Women with dense breast tissue can bi-annually monitor their personalized score in conjunction with annual mammograms. An increasing trend would indicate the need for additional imaging modalities and result in earlier stage diagnosis of breast cancer.

Arterys Inc. is a technology company specializing in medical imaging analytics, aiming to enhance patient care through innovative solutions. Founded in 2007 and headquartered in San Francisco, California, with additional offices in Calgary and Paris, Arterys offers a cloud-based, AI-powered platform that enables radiologists to visualize and quantify blood flow in the body. Its product lineup includes Cardio AI for cardiac imaging, Lung AI for lung analysis, Liver AI for liver diagnostics, and Chest/MSK AI for detecting various thoracic and musculoskeletal conditions. The platform is fully web-based and FDA-cleared, providing clinicians with tools for automatic and interactive reporting. Additionally, the Arterys PHI Service allows physicians to access patient data remotely, further supporting efficient medical practices.

Nexeon MedSystems is a bioelectronics company developing active medical devices for the treatment of chronic medical conditions. The solutions we're developing are a unique blend of traditional device technologies such as electronics, software, mechanical engineering, and material science, as well as pharmaceuticals, protein chemistry, and cell biology.

Redox accelerates the development and distribution of healthcare software solutions with a full-service integration platform to securely and efficiently exchange data. Healthcare delivery organizations and technology vendors connect once and authorize the data they send and receive across the most extensive interoperable network in healthcare. Redox exists to make healthcare data useful and every patient experience a little bit better. It keeps patients at the forefront by helping vendors and providers integrate securely, easily, and at a reduced cost. It was founded in 2014 and is headquartered in Madison, Wisconsin.

PreDxion Bio is a precision medicine diagnostics company that provides ICU doctors with actionable patient immune function data. The company offers MicroKine, a diagnostic tool that measures patients’ immune responses. It enables doctors to identify up to six cytokine proteins using small blood volumes. Using this technology, physicians are able to tailor ICU treatments to each patient's needs. Founded in 2016, PreDxion Bio is based in Ann Arbor, Michigan.

Tueo Health specializes in asthma management through the development of an innovative monitoring system aimed at improving control for children with asthma. The company offers a solution that combines accurate, objective indicators of asthma control with valuable clinical insights tailored to the needs of patients and their families. Utilizing a contactless sensor, the application enables users to monitor and manage asthma treatment progress effectively. This approach not only enhances understanding of asthma conditions but also supports families in achieving optimal health outcomes.

SafeHeal is a medtech company focused on developing innovative medical devices specifically for digestive surgery. Established by MD Start, a medtech accelerator that brings physician inventions to market, SafeHeal has received funding from both MD Start and Sofinnova Partners. The company has been recognized for its contributions to the field, receiving accolades such as the Worldwide Innovation Challenge laureate in 2015 and the Charles Foix grant for its innovations aimed at enhancing the quality of life for elderly individuals. SafeHeal was also acknowledged as the most promising MedTech start-up at the Biovision 2016 investor conference and was a finalist in the global Medtech Innovator competition in 2016.

Cor is a consumer product, with the intention of making it easy to access vital and valuable nutrition and fitness information through your blood. Cor transforms data through machine learning algorithms into “insights.” These insights are information for you based on your lifestyle changes. They include diet, supplements, exercise, and relaxation insights and recommendations. When something you try works for you, you will see an improvement in your indicators. That’s self-efficacy, and that’s just the beginning. You can take these insights and make them into habits. That’s adherence. Over time this becomes permanent improvement. Furthermore, you can share your successes with your family, or anyone you choose. You can help your community by sharing your secrets to success. Cor enables you to see inside your body, quickly and from the comfort of your own home. By providing personalized health insights and key indicator tracking, Cor empowers you to live a longer and healthier life.

Spry Health, Inc. is a digital health solutions company based in Palo Alto, California, established in 2013. It specializes in developing a clinical-grade wearable device and a disease management platform designed to support chronically ill patients. The company's chargeable wristband monitors daily health and fitness activities, providing real-time analytics through a mobile application. This technology enables healthcare organizations to enhance patient outcomes, manage chronic conditions, prevent medical emergencies, and reduce hospitalizations and overall healthcare costs. Spry Health focuses on delivering individualized analytics that assist healthcare payers in efficiently managing the small percentage of patients who contribute significantly to health spending.

Catalia Health Inc. is a San Francisco-based company that develops a cloud-based patient care management platform aimed at enhancing healthcare delivery. Established in 2014, the company integrates artificial intelligence, psychology, and medicine to improve patient engagement and support. Its platform provides healthcare providers with real-time data on patient progress and challenges, facilitating effective communication through mobile apps, web interfaces, and an interactive robotic coach. By delivering tailored conversations to patients, Catalia Health aims to address ongoing healthcare issues, ultimately enabling healthcare professionals to monitor adherence to treatment and improve overall patient outcomes.

Linear Health Sciences is a medical device company creating products for various types of medical tubing based on its proprietary, breakaway safety-valve technology. This platform technology is designed to improve the healthcare experience for patients, caregivers, and healthcare facilities. The company has made substantial progress toward global patent protections and FDA clearance for the Orchid Safety Release Valve. There is a total addressable market of more than $1 billion annually for devices made by the company, which was founded by a physician and two engineers.

SilverCloud Health Limited is a provider of online therapeutic solutions aimed at improving mental wellness. The company develops a platform that offers tailored clinical programs addressing various mental health issues, including emotional health. Founded in 2011 and headquartered in Boston, Massachusetts, with additional offices in Dublin, Ireland, and London, United Kingdom, SilverCloud Health delivers evidence-based digital therapies that enhance user engagement and reduce dropout rates compared to traditional online therapeutic products. By serving the healthcare, medical, and pharmaceutical sectors, SilverCloud Health enables individuals to access professional support quickly and affordably, promoting overall mental health and well-being.

V-Sense Medical specializes in the development of remote medical monitoring devices that utilize advanced radar technology to monitor vital signs without direct contact with patients. By eliminating the need for traditional instruments such as wires, electrodes, and blood pressure cuffs, V-Sense Medical addresses significant challenges in medical facilities, including patient safety and comfort, measurement accuracy, and the efficiency of healthcare delivery. Their innovative approach allows for continuous monitoring of critical health metrics like heart rate and respiratory rate, providing healthcare professionals with real-time insights and alerts regarding patient health. This technology not only enhances the precision of medical assessments but also streamlines workflows, ultimately facilitating quicker and more effective patient care in urgent medical environments.

Sontina Medical is a healthcare technology company focused on developing innovative solutions for the breast biopsy market. Collaborating with leading physicians, Sontina Medical creates advanced technologies that allow for the safe and efficient collection of high-quality biopsy samples. Their products are designed to be accessible and affordable, offering unique features without the need for costly tools or capital equipment. By prioritizing both quality and affordability, Sontina Medical aims to enhance the biopsy procedures available to physicians and improve patient outcomes on a global scale.

Disease Diagnostic Group (DDG) is a pre-revenue medical device company specializing in the development of rapid, accurate, and inexpensive disease diagnostic tests.