MedTech Innovator

SymPhysis Medical focuses on developing innovative medical technologies aimed at treating chronic diseases, with an emphasis on enhancing patient experience and quality of life. The company's flagship product, releaze, addresses malignant pleural effusion (MPE), a common complication in late-stage cancer patients that can lead to severe shortness of breath and chest pain. This therapeutic device is designed for home use, effectively draining excess fluid from the pleural space. By utilizing an active component that enhances fluid removal efficiency, releaze alleviates distressing symptoms and improves treatment accessibility for patients requiring indwelling pleural catheter (IPC) therapies.

AltraTech Limited, established in 2013 and located in Shannon, Ireland, specializes in the design of biosensors and semiconductor chips aimed at DNA testing for food traceability in the agricultural sector. The company has developed a portable device that enhances molecular detection of viral DNA and RNA using advanced enrichment and semiconductor techniques. This innovation achieves the sensitivity and specificity comparable to traditional PCR methods, allowing for rapid and accurate measurement of viral samples. Through these technologies, AltraTech contributes to improving food safety and quality in the agri-business industry.

Venari Medical Limited, founded in 2018 and based in Galway, Ireland, develops innovative medical devices aimed at treating chronic venous diseases (CVD). The company's flagship product, BioVena, employs the body's natural healing processes to provide a more effective and less invasive treatment option for conditions such as varicose veins and venous ulcers. Venari Medical seeks to address the significant gap in treatment, as only a small fraction of the 120 million individuals suffering from venous disease in the US and EU receive adequate care. Their technology not only offers a safer alternative to existing methods but also targets the underserved population of venous ulcer patients who currently rely on ineffective compression bandaging. By widening the indications for superficial venous ablation, Venari Medical aims to reduce the annual costs associated with venous ulcers, which total approximately $33 billion for insurers in these regions. The company's commitment to patient-centered solutions positions it to disrupt traditional treatment practices that have seen limited innovation in recent years.

Starling Surgical is focused on advancing wound closure technology by developing innovative medical devices that enhance the efficiency and effectiveness of surgical sutures. The company manufactures surgical sutures and staplers designed to perform wound closures with the speed and convenience of a skin stapler, minimizing complications such as pain, infection, and unsightly scarring. By improving the wound closure process, Starling Surgical aims to facilitate better healing outcomes for patients following surgical procedures.

CroiValve Limited, founded in 2016 and based in Dublin, Ireland, specializes in the development of a medical device aimed at treating severe tricuspid regurgitation through a minimally invasive procedure. The company's innovative device allows for percutaneous delivery via a vein into the right heart, effectively sealing the gap between the native tricuspid valve leaflets. This approach restores proper valve function and prevents regurgitation, enabling healthcare professionals to address this condition in a safe, effective, and cost-efficient manner. CroiValve's solution is designed to be user-friendly, catering to a broad range of patients suffering from this serious heart issue.

AuriGen Medical Limited, an electrophysiology and structural heart company, develops LAA implants to treat the stroke and arrhythmia risk associated with persistent atrial fibrillation. The company was founded in 2016 and is based in Dublin, Ireland.

Selio is a simple, effective and patent protected technology. The Selio prototype has been rigorously tested in the lab and in subsequent acute pre-clinical in vivo studies with very positive results.

VETEX Medical is an Irish medical device company developing a revolutionary thrombectomy catheter to speedily extract thrombus in a single session, from patients who present with Venous Thrombo-Embolism. Vetex Medical has developed the Vetex thrombectomy catheter as a platform technology for the venous vascular system targeting deep vein thrombosis, AV Fistula grafts and pulmonary embolism. Initially Vetex Medical will target patients with acute DVT in the ilio-femoral veins. The venous thrombectomy market has been underserved for many years but is currently one of the key drivers of the clot management market as clinical evidence and awareness increases.

SilverCloud Health Limited is a provider of online therapeutic solutions aimed at improving mental wellness. The company develops a platform that offers tailored clinical programs addressing various mental health issues, including emotional health. Founded in 2011 and headquartered in Boston, Massachusetts, with additional offices in Dublin, Ireland, and London, United Kingdom, SilverCloud Health delivers evidence-based digital therapies that enhance user engagement and reduce dropout rates compared to traditional online therapeutic products. By serving the healthcare, medical, and pharmaceutical sectors, SilverCloud Health enables individuals to access professional support quickly and affordably, promoting overall mental health and well-being.

AventaMed Ltd. is a medical device company based in Cork, Ireland, specializing in the development of a device for the placement of tympanostomy tubes, commonly known as grommets. As a start-up spun out from the MEDIC research centre at the Cork Institute of Technology, AventaMed has built its foundation on four years of product development aimed at enhancing patient care while lowering healthcare costs. The company's innovative device enables the insertion of ear tubes without the need for general anesthetic, facilitating the treatment of recurring ear infections and hearing loss in both children and adults.

AventaMed Ltd. is a medical device company based in Cork, Ireland, specializing in the development of a device for the placement of tympanostomy tubes, commonly known as grommets. As a start-up spun out from the MEDIC research centre at the Cork Institute of Technology, AventaMed has built its foundation on four years of product development aimed at enhancing patient care while lowering healthcare costs. The company's innovative device enables the insertion of ear tubes without the need for general anesthetic, facilitating the treatment of recurring ear infections and hearing loss in both children and adults.

Incereb is an Irish medical device company based in Dublin, established in May 2011, that focuses on the neonatal intensive care unit (NICU) market. The company specializes in designing and developing disposable Electroencephalography (EEG) and Cerebral Function Monitoring (CFM) products tailored for term and preterm infants. These user-friendly devices require minimal training for setup, thereby reducing the time needed for EEG and CFM monitoring of neonates. Incereb's products are compatible with all brands of EEG and CFM recording equipment. As an award-winning early-stage company, Incereb is committed to investing in research and development, product design, and development to expand its product offerings. Collaborations with leading Irish universities and hospitals allow Incereb to harness local scientific expertise, facilitating the swift commercialization of innovative devices and promoting rapid growth in the NICU sector.