National Science Foundation

Developer of medical devices designed to improve home patient monitoring. The company's devices aid in the diagnostic evaluation as well as monitoring of therapeutic interventions for multiple medical conditions including trauma, dehydration, and sepsis, enabling physicians to simplify home and critical care, prevent unnecessary acute visits, and improve emergency or critical care.

PneumoNIX Medical is developing gel-based technologies to prevent complications associated with percutaneous procedures such as soft tissue biopsies.

Developer of an implantable continuous blood pressure monitoring solution intended for early and accurate detection of dangerous blood pressures that lead to organ damage. The company's device provides advanced notice of changing health status using end-to-end results seamlessly and remotely which connects patients and clinicians through a cloud-based software and analytics platform, enabling timely, cost-effective clinical interventions to intercept and possibly prevent a hypertension crisis.

BioSuperior is a preclinical stage biotherapeutics company developing cost-effective, non-invasive, and easily accessible technologies to cure lung disease and repair damaged lung tissue. They have bio-engineered a novel synthetic pulmonary surfactant prototype, BioSurf, an essential biomaterial required for breathing and having direct therapeutic effects that will be used to deliver potent drugs that restore normal lung function.

the first nasal endoscope for primary care

Colabs is a medical device manufacturing company that focuses on developing an emergency airway and ventilation system. Its device specializes in airway management and ventilation during cardiac arrest. The company was founded in 2012 and headquartered in St, Morgan Hill, California.

Respira Labs, Inc. is a company focused on developing innovative solutions for managing chronic obstructive pulmonary disease (COPD). Based in Mountain View, California, the company has created Sylvee, a wearable device that utilizes advanced technology to continuously monitor lung function and predict COPD exacerbation attacks in real-time. This device is equipped with non-invasive acoustic sensors and employs techniques such as audio signal processing and machine learning to detect "trapped air," an early indicator of potential COPD issues. By enabling early intervention and prevention of exacerbations, Respira Labs aims to enhance patient quality of life and health outcomes while also reducing healthcare costs. Founded in 2018, the company is positioned to transform the landscape of COPD management through its innovative approach.

Relavo, LLC is a medical device company founded in 2018 and based in Baltimore, Maryland. The company focuses on developing solutions to prevent infection related to peritoneal dialysis, specifically through its product, The PeritoneX. This device disinfects contamination points prior to the initiation of dialysis treatment, thereby helping patients with kidney failure to lower their risk of developing peritonitis. By offering an affordable means to enhance safety during peritoneal dialysis, Relavo aims to improve patient outcomes in this critical area of healthcare.

AccuBreath is a medical device company focused on creating an affordable and ultraportable ventilator designed for respiratory support. The company has developed a non-invasive ventilation and respiration monitoring system that offers gentle assistance to patients, particularly during sedation for medical procedures. This innovative ventilator helps to reduce airway obstruction, allowing healthcare professionals to maintain effective ventilation while minimizing potential complications, such as stomach inflation. AccuBreath aims to enhance patient care through its advanced respiratory technology, making high-quality respiratory support more accessible in various medical settings.

Strados Labs, LLC is a medical technology company based in Philadelphia, Pennsylvania, that focuses on innovating respiratory health management through advanced biosensors and artificial intelligence. Founded in 2016, Strados Labs develops a wearable device that provides real-time insights into respiratory metrics such as breathing speed, sounds, and patterns. This device is equipped with a continuous breathing sensor that enables remote monitoring of patients with respiratory conditions like asthma and chronic obstructive pulmonary disease. By connecting the device to a mobile application, patients and healthcare providers can access critical respiratory data, facilitating informed decision-making and improved management of respiratory health.

Lura Health is a company that specializes in developing tooth-mounted sensors designed to monitor oral health through saliva analysis. Founded in 2016 and based in Cambridge, Massachusetts, Lura Health's wireless intra-oral sensors allow users to continuously track key diagnostic metrics related to their oral environment. The sensors are designed to sit comfortably on a single tooth and monitor oral acidity, transmitting data to a mobile application. This technology provides users with meaningful insights and instant feedback, empowering them to take control of their health and improve personal health management by setting and achieving health goals.

Intelligent Medicine provides software and simulation services in medical, artificial intelligence, and virtual reality simulators. Their solution provides architects and facility stakeholders the ability to test and optimize building designs and protocols, thereby reducing infectious spread probability and user congestion.

CathBuddy is a medical device company that features a reusable urinary catheterization system. It specializes in the fields of healthcare, medical, and medical device. It was founded in 2018 and headquartered in New York, United States.

SafeBVM is a medical device startup that addresses the issue of inadvertent hyperventilation by healthcare providers during manual ventilation. The company has developed a safety accessory that ensures optimal airflow delivery while resuscitating patients. This device monitors critical parameters such as airflow and adjusts them based on the patient's airway resistance and lung compliance. By doing so, SafeBVM aims to enhance patient outcomes and reduce complications associated with improper ventilation, including acute respiratory distress syndrome and aspiration pneumonia. The company's focus on cost-efficient innovation reflects its commitment to improving the quality of care in healthcare settings.

PediaMetrix Inc. develops a smart digital tool for pediatric head measurement and monitoring. It offers a flat head syndrome app enables parents to receive accurate measures of their baby's head shape and receive repositioning instructions specific to their baby instantly. The company’s app also enables pediatricians to have access to the data and easy-to-understand analysis of the smart algorithms behind the app to save time and ensure quality care. PediaMetrix Inc. was founded in 2018 and is based in Rockville, Maryland.

Oncurie specializes in developing targeted radionuclide therapies aimed at treating metastatic cancer. The company employs innovative molecular radionuclide technology to deliver radionuclides selectively to metastatic tissues, enhancing treatment efficacy. By focusing on this advanced therapeutic approach, Oncurie seeks to provide healthcare providers with the tools needed to effectively cure patients suffering from breast cancer and other metastatic conditions.

MBF Therapeutics, Inc. is a clinical-stage veterinary oncology company dedicated to developing innovative therapies for dogs and cats with cancer. The company's portfolio includes targeted immunotherapies and small molecule drugs designed to disrupt tumor cell metabolism while sparing normal healthy cells. Notable products in development include MBFT-101, a combination therapy for sarcomas and lymphoma that merges a polyamine transport inhibitor with a potent enzyme inhibitor, and MBFT-102, an immunotherapy based on the tumor suppressor mda-7/IL24, which has shown promise in human cancers. Additionally, MBF Therapeutics is exploring gene-based immunotherapeutic vaccines, aiming to revolutionize cancer treatment and infectious disease prevention in companion animals and livestock. The company collaborates with the Lankenau Institute for Medical Research and is headquartered in Ambler, Pennsylvania.

OPOS operates a patient monitoring and opioid prescriber compliance platform designed to assist primary care and pain specialists across various practice settings. The company focuses on ensuring that opioid prescribers adhere to guidelines set by the Centers for Disease Control and Prevention, state authorities, and medical boards. By providing documented evidence of compliance, along with clinical decision support, OPOS enables healthcare providers to enhance patient outcomes and assess individual and collective risks associated with patients, prescribers, and practices. Their services not only promote regulatory compliance but also aim to reduce prescribing risks and administrative overhead, thus generating revenue through improved operational efficiency in opioid treatment.

BioSapien is a biotech startup that focuses on developing a 3D printed drug delivery platform to provide FDA approved drugs. The startup's device allows chemotherapy to be delivered intravenously through a controlled drug release and enables physicians to reduce harmful side-effects and dramatically reduce costs. BioSapien was established in 2018 and is based in New York.

Aspero Medical, Inc. is a medical device manufacturer based in Boulder, Colorado, established in 2018. The company specializes in gastrointestinal balloon endoscopy procedures, offering a product known as the AP Balloon Overtube. This innovative device utilizes pillar micro-texture technology to improve the performance of endoscopic procedures by enhancing mucosal wall traction and anchoring consistency within the gastrointestinal tract. By optimizing these aspects, Aspero Medical aims to reduce procedure time and sedation requirements, ultimately improving patient outcomes and providing cost-effective solutions for healthcare providers.

Medecipher is a highly innovative early stage company providing innovative solutions to help hospitals improve their operations.

Koda Health, Inc. is a Houston-based company that provides a data-driven, video-based interactive platform aimed at enhancing communication between healthcare providers and elderly patients. Founded in 2020, Koda Health focuses on facilitating personalized end-of-life conversations, allowing patients to articulate their healthcare preferences and make informed decisions about their medical care in advance. The platform utilizes artificial intelligence to guide patients through discussions about their quality of life, designating power of attorney, and identifying emergency contacts. By doing so, Koda Health helps ensure that patients' healthcare preferences are respected while simultaneously aiding healthcare systems in reducing unnecessary expenditures. The company also collects valuable data on patient personas and care preferences, enriching the understanding of patient needs in clinical settings.

Clairways specializes in smart lung monitoring technology designed for pharmaceutical clinical trials. The company develops a wearable digital lung monitor that captures critical respiratory metrics for individuals suffering from conditions such as asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis (CF). Fitted to the body, this device employs acoustic sensors and machine learning technology to detect and characterize various respiratory metrics. The collected data is presented in an accessible format, allowing healthcare providers to easily monitor and assess patients' respiratory health over the long term.

Green Sun Medical, LLC is a medical device company established in 2013 and located in Fort Collins, Colorado. The company specializes in the design, development, and manufacturing of orthotic braces aimed at treating Adolescent Idiopathic Scoliosis (AIS) and Kyphosis. Its innovative products are designed to correct spinal deformities, providing support and alignment for patients with these conditions.

Biochip Labs, founded in 2019 and headquartered in Cleveland, Ohio, specializes in laboratory testing services for blood disorders, particularly sickle cell disease and thalassemia. The company offers a variety of proprietary microfluidic biomarker assays that assess blood cell adhesion, red blood cell deformability, whole blood rheology, and endothelialized microfluidics. These assays are designed to evaluate the efficacy of emerging targeted and curative therapies, allowing clinicians to effectively monitor patient responses to treatment. By focusing on accurate and high-quality testing, Biochip Labs aims to advance the understanding and management of blood disorders.

xMD Diagnostics operates in the healthcare industry focusing on biotechnology business. The company was formerly known as Bay Resources Development Group. The company is headquartered in Annapolis, Maryland. xMD Diagnostics uses high-throughput microdissection technology for the diagnosis of cancer.

Developer of gastrointestinal therapeutic device designed for the alleviation of postoperative ileus and the restoration of gastrointestinal motility. The company's device aims to revolutionize medical science by using bioelectronic medicine for the treatment of diseases and injuries incurable pharmaceutically and is capable of developing miniaturized implantable device, while retaining sophisticated functionality with various electrode shape and number, enabling clinicians to treat diseases and injuries through neuromodulation.

MileMarker is a web-based assessment platform designed to enhance medical training through real-time evaluations. Developed by leaders from the Johns Hopkins University School of Medicine, it addresses the challenges of evolving competency requirements in medical education while reducing training costs. The platform enables residents to log operative cases and conduct self-assessments, which are then followed by evaluations from attending surgeons. These assessments can be completed swiftly, integrating seamlessly into the workflow of medical professionals. By capturing real-time data on resident performance, MileMarker allows for continuous monitoring and comparison of individual progress against peers, facilitating a more efficient training process. The software not only improves communication and efficiency within residency programs but also has the potential to significantly increase program revenue and reduce training duration. Accessible on any mobile device or computer, MileMarker positions itself as a vital tool for residency programs aiming to meet regulatory demands and enhance the quality of medical education.

Kodikaz Therapeutic Solutions is focused on advancing cancer treatment by developing targeted therapies aimed at eradicating cancers while minimizing side effects. The company utilizes its innovative Zip-Code™ Technology platform, a first-in-class delivery system that facilitates cell-specific genomic transfer for both RNA and DNA applications. Rooted in discoveries from human cancers, this platform addresses the limitations associated with traditional viral delivery methods, providing a more effective and safer alternative. Kodikaz's research generates valuable in-vitro and in-vivo data across various oncological applications, including pancreatic, myeloma, and colorectal cancers, supporting the development of curative gene transfer technologies.

Infusense is a platform biosensor to measure propofol levels in patients undergoing anesthesia and sedation.

Compact Medical Solutions LLC, founded in 2016 and based in Indianapolis, Indiana, specializes in the development of a medical bag-valve-mask (BVM) known as Butterfly BVM. This innovative device is designed to assist medical personnel in ventilating patients experiencing respiratory distress. The Butterfly BVM enhances resuscitation efforts by preventing hyperventilation, ensuring that caregivers can safely and effectively manage patients who are not breathing properly. Through its focus on creating ultra-compact breathing solutions, Compact Medical aims to improve emergency response in critical situations.

Empo Health specializes in in-home health monitoring, focusing on early detection of diabetic foot conditions to prevent amputations. The company has developed innovative bathroom scales and a digital health platform that provide reliable visual data for patients and clinicians outside of clinical settings. By integrating these tools into everyday life, Empo Health aims to enhance patient care and contribute to better health outcomes.

KovaDx focuses on improving healthcare access for individuals suffering from Sickle Cell Disease and other hemolytic anemias through an innovative point-of-care solution. The company has developed a health monitoring tool that utilizes Quantitative Phase Imaging and deep learning technology to provide affordable and easy-to-use diagnostics. This system is designed to bridge gaps in care for blood diseases, enabling better management of blood health. By offering a diagnostic and monitoring device, KovaDx aims to enhance the understanding of treatment impacts and improve patient outcomes. Ultimately, the company seeks to support individuals with Sickle Cell Disease in enhancing their overall prognosis and quality of life.

Developer of virus-resistant live bacterial products designed to modulate the human microbiome. The company targets the viral components of the gut microbiome to treat disease and focus on healthy gut bacteria and their predatory phages to engineer resistant strains, and also develops a new class of live biotherapeutics, enabling medical science professionals to specifically target phages or viruses with a specific affinity for inducing lysis.

Respira Labs, Inc. is a company focused on developing innovative solutions for managing chronic obstructive pulmonary disease (COPD). Based in Mountain View, California, the company has created Sylvee, a wearable device that utilizes advanced technology to continuously monitor lung function and predict COPD exacerbation attacks in real-time. This device is equipped with non-invasive acoustic sensors and employs techniques such as audio signal processing and machine learning to detect "trapped air," an early indicator of potential COPD issues. By enabling early intervention and prevention of exacerbations, Respira Labs aims to enhance patient quality of life and health outcomes while also reducing healthcare costs. Founded in 2018, the company is positioned to transform the landscape of COPD management through its innovative approach.

HC Simulation, founded in 2011 and headquartered in Canton, Mississippi, focuses on developing advanced products that utilize the HumMod engine to simulate human physiology. The company's offerings allow users to explore physiological interactions that are often difficult to observe through traditional methods. By providing high-quality simulations, HC Simulation aids in the ideation, development, and prediction of innovative medical devices and pharmaceuticals, enhancing the understanding of complex biological systems.

Sequitur Health develops a blood biomarker monitoring device with the aim of saving, extending, and improving people's lives. The company was founded in 2019 and is headquartered in Scottsdale, Arizona.

Hermes Life Sciences develops solutions to improve the accuracy and accessibility of blood testing at the point of care. The company was founded by Sasank Vemulapati.

BioSense8 develops biosensors for use in human and animal healthcare, and environmental wellness. The company was founded in 2020 and is headquartered in Boston, Massachusetts.

Optical Metrology Solutions, headquartered in Niskayuna, New York, specializes in consulting services related to optical metrology equipment. The company offers application evaluations to identify the most suitable off-the-shelf tools and assists in the procurement of specifications. Additionally, it provides training to enhance the understanding and application of these tools. By focusing on making in-process measurements more economically viable and improving machine utilization, Optical Metrology Solutions aids companies in testing their parts for compliance throughout nearly all stages of the optical production process.

LumenAstra, founded in 2020 and headquartered in Longmont, Colorado, develops non-invasive, wearable deep-tissue temperature sensors aimed at enhancing patient care in various medical contexts. The company's innovative technology allows for the external measurement of internal temperature, making it particularly useful in cancer hyperthermia therapy. Additionally, LumenAstra's sensors have applications in monitoring hypothermia during aortic dissection repair, brain temperature in neonatal hypoxia-ischemia cases, and internal heat stress in military and hazardous environments. This technology enables medical professionals to effectively protect patients from serious injuries and fatalities related to heat stress.

MedChem Partners is a medicinal chemistry CRO that specializes in developing small molecule therapeutics. The company was founded in 2006 and is headquartered in Lexington, Massachusetts.

Developer of a medical device designed to use for endoscopic surgeries. The company's device is compatible with standard endoscopes for tissue approximation for surgeries with an image-guided suturing system, enabling hospitals to reduce the procedure time and mortality rates.

Cordance Medical is a medical device company focused on developing innovative therapies for central nervous system (CNS) pathologies, including primary and metastatic cancers, Alzheimer's disease, and Parkinson's disease. The company has created a non-invasive ultrasound system that precisely opens the blood-brain barrier, allowing for targeted delivery of systemically administered drugs to specific brain regions. This low-power ultrasound technology aims to enhance diagnostic and therapeutic options for patients, providing a safe and effective means to address complex neurological conditions.

Operator of a digital health platform intended to make a clinical encounter productive by improving patient-doctor communication. The company's platform is advantageous for public health providers that serve a disproportionately high number of patients who do not speak English and improves access to care for people with communication barriers, enabling disadvantaged patients to accurately and remotely self-report symptoms that are often missed.

QAS.AI focuses on developing and commercializing advanced software that enhances the functionality of image-guided surgical equipment. The company specializes in image analysis and treatment management, creating tools that accurately assess tissue perfusion status and identify vessel occlusion. This software is designed for use during surgical procedures, enabling clinicians to detect areas of inadequate blood flow in the brain and to evaluate the effectiveness of aneurysm correction six months post-embolization. By providing real-time assistance during endovascular surgeries, QAS.AI aims to improve patient outcomes and support healthcare professionals in delivering precise interventions. The multidisciplinary team at QAS.AI includes specialists in biomedical engineering, neurosurgery, and pathology, ensuring a comprehensive approach to surgical technology.

Alerje, Inc. is a Detroit-based company that develops an innovative epinephrine auto-injector designed to fit into a smartphone case, enhancing accessibility for individuals with food allergies. The device is complemented by a mobile application that alerts a user’s CareCircle, which includes emergency services, family, friends, caregivers, and medical professionals, providing crucial location and health information during emergencies. Founded in 2015, Alerje focuses on improving the quality of life for those affected by food allergies by integrating emergency medicine with digital health solutions. The platform aims to foster better dietary decisions among families, allergists, insurers, and pharmaceutical companies through improved patient adherence and real-time communication.

Desert Valley Tech, founded in 2018 and based in Mesa, Arizona, specializes in developing cold chain storage systems designed to preserve temperature-sensitive items such as blood, pharmaceuticals, biologics, and organs. The company's innovative system maintains pre-set temperatures while optimizing power consumption, providing customizable modular storage solutions suited for various scenarios. This technology enhances the ability of medical professionals to ensure the safe transport and storage of critical medical supplies, ultimately improving survival rates in challenging and remote medical environments.

Ethos Medical Inc is a medical device manufacturer specializing in ultrasound-based needle guidance systems for procedures such as spinal taps and epidurals. Founded in 2018 and headquartered in Duluth, Georgia, the company has developed the Iris, a handheld device that assists practitioners in accurately navigating needles into the spine. This system interfaces with existing ultrasound machines, providing real-time tracking and guidance, which enhances the precision of needle-based procedures. Ethos Medical aims to improve the efficiency and accuracy of healthcare delivery while maintaining cost-effectiveness.

JuneBrain is an early start-up company that empowers multiple sclerosis patients through the power of telemedicine. It aims to develop a wearable and non-invasive imaging device that enables multiple sclerosis patients to monitor their disease activity at home, leading to earlier detection of MS attacks and improved monitoring of treatment efficacy. Its long-term goal is to extend the use of our device into the broader neurodegenerative disease population, thus creating a pathway towards more frequent, widely-accessible monitoring of brain health. ​It was founded in 2017 and is headquartered in Washington, DC.

Lisa Health is a digital platform for menopause and midlife women's health. Menopause is a transition every woman around the globe will experience. Eighty-five percent will have symptoms that adversely impact their health, quality of life, relationships, and productivity at work. Lisa Health manages the menopause journey and midlife wellbeing with personalized, science-based, community-supported guidance.

NeuroLogic Solutions, established in 2016 and based in Baltimore, Maryland, develops advanced EEG analytic software aimed at enhancing the diagnosis and treatment of epilepsy. The company’s platform analyzes electroencephalography data to identify regions of the brain affected by seizures, which assists clinicians in diagnosing epilepsy more accurately and guiding surgical interventions. By providing insights that can lead to seizure freedom, NeuroLogic Solutions seeks to improve patient outcomes and contribute to the overall effectiveness of epilepsy care.

Lightengale is a developer of medical devices focused on enhancing safety in healthcare settings, particularly in intensive care units. The company has created an innovative infusion line that utilizes light-emitting cables to illuminate individual intravenous (IV) lines from the pump to the patient. This design addresses the critical issue of line mix-ups and medication delivery errors, which can pose significant risks to patient safety. By providing visual cues for nurses to accurately trace IV lines, Lightengale's technology allows healthcare professionals to dedicate more time to patient care, ultimately improving the overall quality of medical treatment.

Current Surgical is a surgical device company that develops precise tools for the treatment of solid tumors. The company was founded in 2020 and has its headquarters in Washington, DC.

Wildlife Protection Management, Inc. manufactures a dart system for delivering vaccines and contraceptives on the horses. Its system also allows for the delivery of radio-frequency identification (RFID) chips for identifying each horse and monitoring the health and location. Wildlife Protection Management, Inc. was incorporated in 2018 and is based in Albuquerque, New Mexico.

CAIRA Surgical is a medical software and technology company on a mission to reduce costs and improve patient outcomes in orthopedic care. CAIRA Surgical develops advanced joint replacement software, scanning, and precision radar technologies designed for reliability, intuitive adoption, and global accessibility. CAIRA Surgical strives to empower surgeons by inventing and investing in new, proprietary technologies that simplify workflows and enable better patient outcomes in joint replacement.

Winter Innovations is focused on developing medical devices aimed at enhancing patient outcomes following orthopedic injuries. The company is working on EasyWhip, a patent-pending suturing needle specifically designed for orthopedic ligament and tendon reconstruction surgeries. This innovative device simplifies and standardizes the whip stitching technique, providing benefits such as ease of use, speed, stability, and versatility. By improving the speed and consistency of orthopedic reconstruction procedures, Winter Innovations aims to support surgeons in delivering more effective treatments for their patients.

Precision Theranostics is a biotechnology company based in Baltimore, Maryland, founded in 2019. The company focuses on developing prognosis-based intervention strategies aimed at the early detection and treatment of fatal diseases. Its innovative platform is designed to estimate disease progression, particularly for respiratory diseases and age-related disorders. By creating novel diagnostics, therapeutics, and prognosis-based therapies, Precision Theranostics enables healthcare providers to deliver timely diagnoses and interventions, ultimately improving survival rates and preventing the progression of chronic and fatal conditions.

CellDrop Biosciences, established in 2017 and based in Laramie, Wyoming, specializes in hydrogel-based technology for point-of-care diagnostics and targeted biomaterial delivery. The company focuses on developing hydrogel platforms that enable precise control over chemical and biological systems. Its innovations aim to facilitate the healing of equine musculoskeletal injuries efficiently, while also minimizing the risk of re-injury. By providing effective diagnostic and treatment solutions, CellDrop Biosciences addresses critical needs within the veterinary medical community.

Supremetric develops forensic applications to help with the forensic analysis of biological stains. The company was founded in 2019 and is headquartered in Glenmont, New York.

Radiosight, founded in 2020 and headquartered in Hoboken, New Jersey, specializes in ultra-wide imaging technology aimed at improving the diagnosis of skin cancer and assisting in surgical decisions. The company has developed an innovative technique that enhances image resolutions, offering a handheld 3D imaging device that reveals the underlying shape and profile of suspicious tissue. This technology enables dermatologists to better visualize the margins before biopsy, thereby increasing the accuracy of skin lesion excisions. Through its advanced imaging solutions, Radiosight seeks to enhance the effectiveness of skin cancer treatment and diagnosis.

Grapevine Health is a data-driven health media company focused on improving health literacy among underserved communities. By utilizing technical expertise and trusted communicators, the organization provides culturally appropriate health information that is both relatable and understandable. Their services assist health systems, insurers, and medical providers in enhancing community outreach and engagement, ensuring that health information is accessible and empowering for patients. Through empathetic storytelling and tailored communication strategies, Grapevine Health aims to democratize health information and support the maintenance of healthy behaviors within these communities.

Manufacturer of surgical devices intended to enhance surgeon performance. The company's system provides critical decision-making information along with superior performance and a smart balance of features and ease the way surgeons approach soft tissue management, enabling surgeons to extend their tactile reach to the target tissue with AI guidance, minimize inefficient workflows, reduce costs, and eliminate toxic waste disposal.

HealthTrends.AI is a trusted third party delivering ongoing authoritative health information that is independently auditable. Our mission is to help organizations turn health data into actionable information. We offer a platform-agnostic solution embedded in our products. Products are available as streaming feeds, APIs, and dashboards enabling flexible integration with 3rd party tools (Power BI, Tableau, etc.). Our tools are designed to be easily accessible and plug into and enhance your existing in-house systems with an intuitive platform.

Ortuvo develops 3D printing research tools for tissue engineering and custom bio-inks for the healthcare and biotech industries. The company was founded in 2020 and is headquartered in Baltimore, Maryland.

Developer of life science platform intended to provide accurate methods to test dangerous endotoxins. The company provides advanced healthcare innovations for the detection of blood-borne pathogens, enabling physicians to develop a rapid and sensitive diagnostic for detecting bloodstream infection.

Enable Therapeutics is a biotechnology company developing a patented drug delivery platform. The company was founded in 2020 and is headquartered in Hopedale, Massachusetts.

Cobio Diagnostics is a biotechnology company that develops diagnostics for bacterial identification and phenotypic antibiotic resistance testing. The company was established in 2016 and is based in Golden, Colorado.

BondTrue LLC is a medical device company focused on enhancing surgical accuracy through automation. The company's patented device automates the processes of surgical incisions and closures, allowing for rapid approximation and repair of surgical wounds. This innovation enables surgeons to execute clean, consistent incisions and achieve precise suturing. Recently, BondTrue received a Phase II Maryland Industrial Partnerships (MIPS) award from the Maryland Technology Enterprise Institute, which provides funding for research and development in collaboration with universities. The $100,000 grant will support the continued development of the device, following successful completion of Phase I. BondTrue plans to refine its prototype designs, which will undergo further research and testing to advance the commercialization of this medical technology.

Instapath Inc. specializes in designing and developing a microscopy system that enhances the evaluation of cancer biopsies. The company’s technology allows for imaging biopsy samples at subcellular resolution immediately after removal, while also preserving the tissue for future analysis. This innovation aims to address a critical need, as over 7 million Americans undergo biopsy procedures annually, with a significant portion failing to provide accurate diagnoses, leading to costly repeat procedures. By improving rapid on-site evaluation of biopsies, Instapath’s system reduces the necessity for these repeat procedures, thereby increasing operating room efficiency and potentially boosting hospital revenue. Founded in 2017, Instapath is headquartered in New Orleans, Louisiana.

Nanoxort, founded in 2018 and based in Auburn, Alabama, specializes in developing diffusive magnetic fractionation (DMF) technology that allows precise control over the properties of magnetic nanomaterials. This innovative technology is particularly significant in the healthcare sector, as it enhances contrast agent injections for patients undergoing MRI scans. By improving image resolution, Nanoxort's technology reduces the toxic effects associated with traditional MRI contrast agents, particularly gadolinium, which poses risks for individuals with compromised kidney function. Consequently, Nanoxort's advancements contribute to safer imaging practices, minimizing gadolinium exposure for patients who require frequent MRI procedures.

PediaMetrix Inc. develops a smart digital tool for pediatric head measurement and monitoring. It offers a flat head syndrome app enables parents to receive accurate measures of their baby's head shape and receive repositioning instructions specific to their baby instantly. The company’s app also enables pediatricians to have access to the data and easy-to-understand analysis of the smart algorithms behind the app to save time and ensure quality care. PediaMetrix Inc. was founded in 2018 and is based in Rockville, Maryland.

Spatio Metrics presents architecture as a new tool for advancing health by filling the gap between design, data, and performance. The company helps hospitals manage facilities with a dashboard that shows how spaces influences patients’ health outcomes. The company's product analyzes floor plans, reveals design gaps, and recommends performance improvements. Hospital administrators are encouraged to make smarter design investments by quantifying the human and financial impact of design.

Sperry Bio provides the sperry micro-coring system, which is a medical device and has not been evaluated for marketing clearance. They address current prioritized objectives of regenerative skin medicine research programs within the army medical research and materiel command clinical and rehabilitative medicine research program.

PainScan specializes in developing biomedical devices aimed at measuring and mapping pain intensity on a three-dimensional (3D) image of the human body. The company's innovative medical device incorporates ultrathin pressure sensors embedded in a clinician's glove, along with cameras that track palpation locations. By integrating data from various subjective and objective biosensors, the device allows for a detailed assessment of pain intensity at each palpation site. This technology enables clinicians to visualize pain comprehensively within the peripheral nervous system, enhancing their ability to diagnose and treat pain-related conditions.

Oncospace is a medical device manufacturing company that specializes in radiation oncology. It features an AI-based platform that takes advantage of this knowledge to personalize each patient’s treatment, minimize side effects, and maintains the quality of life. The company was founded in 2019 and headquartered in Baltimore, Maryland.

Gradient Medical develops novel interventional oncology services to bring ACE therapy to the clinic. The company was founded in 2020 and is headquartered in Raleigh, North Carolina.

ReSuture specializes in creating advanced physical simulations aimed at enhancing surgical training, particularly for open vascular procedures. The company develops innovative surgical instruments that address contemporary challenges in medical simulation. These instruments provide realistic physical stimulation, enabling users to effectively learn vascular surgical skills in a controlled and monitored setting. By improving psychomotor skills and minimizing training time, ReSuture allows medical practitioners to replicate the mechanical properties of human vascular tissue, thereby facilitating repeated and realistic simulations of vascular surgery. This approach not only enhances the training experience but also contributes to better preparedness for actual surgical procedures.

Operator of a biotechnology company intended to improve research, health, and wellness by providing access to accurate and cost-effective specimen collection devices. The company's device stabilized sensitive tests and facilitates remote specimen collection, including urine, serum, plasma, or any other bodily fluid, and simple transportation at ambient temperature, enabling people in the community to access accurate and cost-effective diagnoses.

Vena Vitals makes a small sticker that monitors blood pressure continuously. Vena Vitals showed that it works in the operating room and is as accurate as the best tools doctors have today, at a fraction of the cost. We're a team of health tech scientists with multiple past startups and exits, and we've built products that have scaled to over 2M users.

Spero Therapeutics, a clinical-stage biopharmaceutical company based in Cambridge, Massachusetts, specializes in developing novel therapies for multi-drug resistant (MDR) bacterial infections and rare diseases. Its key product candidates include tebipenem pivoxil hydrobromide, an oral carbapenem-class antibiotic intended for adults with MDR Gram-negative infections, and SPR206, an intravenous agent targeting MDR Gram-negative infections in hospital settings. Additionally, the company is advancing SPR720, an oral antibiotic designed for treating pulmonary non-tuberculous mycobacterial disease. Spero Therapeutics has established various collaborations and license agreements to support the development and commercialization of its products, including partnerships with Meiji Seika Pharma, Everest Medicines, and the Bill & Melinda Gates Medical Research Institute. Founded in 2013, Spero aims to address the critical need for effective treatments against serious bacterial infections using innovative approaches and mechanisms.

Progenitor MDX provides a comprehensive and customizable solution to manage COVID-19 infections from start to finish. We not only deliver testing results, but also help you develop actionable plans for infection management, providing reassurance to your communities.

O2M Technologies develops oxygen imaging devices for effective cancer and regenerative medicine treatments. The company was founded in 2017 and is headquartered in Chicago, Illinois.

GMJ Technologies develops microanalytical technologies for biopharmaceutical and biomedical applications. The company was founded in 2018 and is headquartered in Seattle, Washington.

BioAesthetics Corporation, founded in 2015 as a spin-out from Tulane University, specializes in developing innovative reconstruction solutions for breast cancer patients who have undergone mastectomies. The company's primary product is a tissue-engineered nipple-areolar complex (NAC), designed to facilitate the regeneration of the nipple and areola during the breast reconstruction phase. This biologically derived graft serves as an acellular, off-the-shelf option for plastic and reconstructive surgeons, allowing the patient's own cells to integrate and restore the NAC. Currently in the pre-clinical phase, this patent-pending technology aims to improve surgical outcomes and enhance the quality of life for patients with incomplete or removed NACs due to disease, surgery, or birth defects. BioAesthetics is headquartered in Research Triangle Park, North Carolina.

BiomeSense is revolutionizing human microbiome research by developing novel technologies to enable investigators to collect, store, and analyze the daily microbiome profiles of clinical trial participants in a low-cost, scalable way. By enabling daily profiling, the platform allows investigators the unprecedented ability to tie microbiome changes directly to clinical outcomes in real time, dramatically increasing the research discovery potential.

RadWave Technologies Inc. is an early-stage company based in Saint Paul, Minnesota, that specializes in developing advanced technologies for minimally invasive medical procedures. Founded in 2018, the company has created an electromagnetic navigation system that enhances the accuracy of object tracking during complex surgical operations. This innovative system provides performance tracking services for image-guided, minimally invasive, and robotic procedures, allowing medical professionals to effectively locate surgical instruments and tools within the human body, even in scenarios where there is no direct line of sight. Through its cutting-edge technology, RadWave Technologies aims to improve surgical outcomes and enhance the capabilities of healthcare providers.

Lasarrus is a Baltimore-based company founded in 2013 that specializes in developing wearable devices for patients with chronic obstructive pulmonary disease (COPD). The company's innovative device is designed to enhance physical therapy by facilitating telemedicine and remote monitoring. It captures physiological and range-of-motion data, allowing patients to track their health routines effectively. Lasarrus aims to provide an affordable, comfortable, and non-invasive solution that accelerates recovery for users, improving their overall health management.

Developer of a medical technology designed to offer treatment for heart failure. The company's technology specializes in offering advanced transcatheter heart valve therapies, enabling patients to prevent structural heart failure.

Novonate is a healthcare technology company focused on developing medical devices for neonatal care. Its primary product is designed for use in neonatal intensive care units, specifically to protect the umbilical catheter insertion site from complications associated with central lines, such as migration and malposition. This innovative device helps stabilize the umbilical cord during medical procedures, including phlebotomy, thereby enhancing patient safety and care in vulnerable newborns.

OmnEcoil Instruments, founded in 2016 and based in Portland, Oregon, specializes in developing an innovative device for prostate cancer detection and tissue sampling. This device enhances the diagnostic process by integrating MRI technology with tissue sampling, thereby eliminating the need for traditional ultrasound-guided biopsies. By providing a more efficient and accurate method for detecting prostate cancer, OmnEcoil Instruments aims to improve patient outcomes and streamline the diagnostic workflow for healthcare providers.

Developer of a healthcare device designed for continuous monitoring and early detection of health issues based on urine analysis. The company's device uses mass spectroscopy-based sensors to track changes in urine over time, enabling patients and doctors with timely intervention, and potentially preventing complications or hospitalizations.

Developer of medical devices intended to address unmet needs in gynecologic surgery. The company offers specialized pre-commercial medical devices for minimally invasive surgical tools, enabling medical practitioners to get proper surgical assistance to treat women.

Ionica Sciences™ is utilizing a new technology platform to meet urgent needs in clinical diagnostics.The ability to rapidly and accurately identify the presence of diseases would provide clinicians with the ability to reduce suffering of their patients, the use of antibiotics, and healthcare costs that result from mis- or missed diagnoses.

FloBio specializes in point-of-care diagnostics focused on assessing bleeding risk through real-time blood analysis. Founded in 2017 and based in Philadelphia, PA, the company has developed an innovative fluidic-based diagnostic platform that utilizes microfluidic technology. This platform allows for rapid and precise measurements of blood clotting function under physiological conditions, enabling clinicians to make informed decisions and personalize patient management swiftly during critical situations.

Flotherm develops a thermal compression device that maintains normothermia in a timely manner. The company's headquarters are in Los Angeles, California.

Relavo, LLC is a medical device company founded in 2018 and based in Baltimore, Maryland. The company focuses on developing solutions to prevent infection related to peritoneal dialysis, specifically through its product, The PeritoneX. This device disinfects contamination points prior to the initiation of dialysis treatment, thereby helping patients with kidney failure to lower their risk of developing peritonitis. By offering an affordable means to enhance safety during peritoneal dialysis, Relavo aims to improve patient outcomes in this critical area of healthcare.

FYR Diagnostics, founded in 2016 and based in Missoula, Montana, focuses on developing biomarker detection technology aimed at addressing chronic diseases in both human healthcare and agriculture. The company aims to tackle significant clinical challenges by commercializing innovative technologies that enhance the prediction, diagnosis, and management of diseases. This approach targets disorders that currently suffer from inadequate treatment and diagnostic options, thereby offering potential solutions for healthcare professionals and agricultural sectors facing substantial unmet needs.

Dynamic Entropy Technology manufactures medical devices with the purpose of improving new technologies in the field of health sciences. The company was founded in 2018 and is headquartered in Pasco, Washington.