National Science Foundation

The National Science Foundation (NSF), established in 1950 and located in Alexandria, Virginia, is an independent federal agency dedicated to advancing fundamental research and education across all scientific and engineering disciplines. With an annual budget of approximately $7.8 billion, the NSF operates America's Seed Fund, which allocates nearly $200 million each year to support startups and small businesses through the Small Business Innovation Research (SBIR) program. This initiative provides non-dilutive funding of up to $1.5 million to assist in research and development efforts, thereby facilitating the transformation of scientific discoveries into commercially viable products and services. By helping to de-risk technology, the NSF plays a crucial role in fostering innovation and addressing societal challenges through scientific advancements.

James Donlon

Program Director

Sean L. Jones

Assistant Director for Mathematical and Physical Sciences

Sethuraman Panchanathan

Director

Ben Schrag Ph.D

Program Director and Policy Liaison, SBIR / STTR

Past deals in Washington

Transparent Path

Grant in 2023
Transparent Path is a technology provider specializing in supply chain visibility, particularly for the food industry. The company utilizes Internet of Things (IoT) sensors, edge computing, and artificial intelligence to create a secure and scalable platform that allows food manufacturers, processors, logistics partners, and retailers to monitor and manage supply chain issues in real-time. By offering both software and hardware solutions, Transparent Path enables its clients to gain insights into logistics, product quality, and risk management, helping them to detect and address problems before they escalate. This proactive approach not only enhances operational efficiency but also reduces costs and waste associated with perishable goods. Founded by Eric Weaver, who has extensive experience in enterprise transformation, Transparent Path aims to foster a more resilient and agile supply chain.

Ocean

Grant in 2022
Eco-Shelter is a social enterprise founded in 2017 by Alexa Bednar, based in Seattle, Washington. The company focuses on providing safe and affordable roofing solutions for low-income households in India. It specializes in sustainable building materials, offering an eco-roof panel made from resin-coated bamboo mats. These panels are pressed and sealed to create a strong, lightweight, water-resistant, and flame-resistant roofing option. Through its innovative products, Eco-Shelter aims to improve living conditions for underprivileged communities by delivering accessible and environmentally friendly building solutions.

Ryp Labs

Grant in 2022
Stixfresh is focused on developing and commercializing groundbreaking and innovative technologies that will significantly reduce food waste via all-natural methods. Our first product, the Stixfresh stickers, have the potential to do just that. Stixfresh can reduce certain fresh fruit waste across the entire supply chain by extending their shelf-life, and keeping them fresher, longer. The Stixfresh technology, consists of an FDA-approved sticker that is coated with our patent-pending formulation, which is composed of 100% natural ingredients. The sticker is simply peeled and applied to the surface of certain fruits in order to extend its shelf-life by up-to 14 days. The formulation includes compounds that work together to create a protective layer around the fruit, which slows down the ripening process. Independent studies have shown that fruits treated with the Stixfresh sticker have increased sweetness, higher retention of moisture, and sustained cellular structure resulting in increased firmness.

QuadraLynx

Grant in 2021
Quadralynx specializes in the development of wearable biometric devices tailored for adults experiencing motor speech disorders, particularly those who face challenges with volume control due to Parkinson's disease and similar neurological conditions. The company's innovative device employs biofeedback technology to alert users through vibrations when their voice reaches a pathological state. By focusing on speech and voice improvement, Quadralynx aims to enhance the quality of life for individuals affected by these disorders.

Sugarcube Systems

Grant in 2021
Developer of an online CAD tool intended to optimizes designs. The company's online CAD tool is accurate and enables self calibration, the performance control technology also enables devices to change their effective mass, damping, and stiffness on demand enabling students, researchers, and startups to facilitate a MEMS community of shared designs and compact models.

Map Collective

Grant in 2021
Map Collective specializes in developing an interactive mapping platform that utilizes artificial intelligence to analyze and visualize environmental data. This Software-as-a-Service solution integrates seamlessly with Geographic Information Systems (GIS) to provide users, including companies and governments, with essential tools for monitoring various environmental factors such as air quality, carbon footprints, and supply chain emissions. The platform facilitates traceability and emissions mapping, supports biodiversity assessments, aids in energy hub planning, and assists in transitioning to a circular economy. By offering a comprehensive view of the carbon impact on the environment, Map Collective empowers users to make informed decisions regarding sustainability and environmental management.

JuneBrain

Grant in 2021
JuneBrain is an early start-up company that empowers multiple sclerosis patients through the power of telemedicine. It aims to develop a wearable and non-invasive imaging device that enables multiple sclerosis patients to monitor their disease activity at home, leading to earlier detection of MS attacks and improved monitoring of treatment efficacy. Its long-term goal is to extend the use of our device into the broader neurodegenerative disease population, thus creating a pathway towards more frequent, widely-accessible monitoring of brain health. ​It was founded in 2017 and is headquartered in Washington, DC.

Recurrent

Grant in 2021
Recurrent Motors, Inc. specializes in analyzing electric vehicle (EV) batteries and providing detailed reports that assist car dealers and private buyers in purchasing used electric cars. Founded in 2020 and based in Seattle, Washington, the company offers tools that assess battery health, life expectancy, and current maximum range of EVs, addressing the complexities involved in understanding these factors as vehicles age. By delivering non-invasive tests and leveraging a national database of vehicle data and history, Recurrent enables informed decision-making for both dealers and consumers. Additionally, the company provides personalized monthly battery analyses for EV owners, enhancing their understanding of their vehicles' performance over time.

Current Surgical

Grant in 2021
Current Surgical is a surgical device company that develops precise tools for the treatment of solid tumors. The company was founded in 2020 and has its headquarters in Washington, DC.

SunFly

Grant in 2021
SunFly Brands, Inc. develops invisible ink stamps/ultraviolet indicator stamps that a user wear underneath their sunscreen, which will saturate with color indicating when to reapply sunscreen. The company was incorporated in 2016 and is based in Seattle, Washington.

Grapevine Health

Grant in 2021
Grapevine Health is a data-driven health media company focused on improving health literacy among underserved communities. By utilizing technical expertise and trusted communicators, the organization provides culturally appropriate health information that is both relatable and understandable. Their services assist health systems, insurers, and medical providers in enhancing community outreach and engagement, ensuring that health information is accessible and empowering for patients. Through empathetic storytelling and tailored communication strategies, Grapevine Health aims to democratize health information and support the maintenance of healthy behaviors within these communities.

NLM Photonics

Grant in 2021
Nonlinear Materials Corp. is a developer of next-generation nano-scale photonics. Nonlinear Materials Corporation (NLM) has exclusively licensed proprietary materials and methods developed by University of Washington researchers to deliver “fiber-optic networks on a chip.”

Aquagga

Grant in 2021
Aquagga is a spinout company from the University of Alaska and the University of Washington, focused on developing innovative wet-waste treatment technology. The company utilizes supercritical water (sH2O) technology in conjunction with advanced additive manufacturing to effectively clean and desalinate various industrial effluents. By reducing environmental contaminants with lower energy consumption, Aquagga aims to provide significant social and environmental benefits. Its approach seeks to address pressing environmental challenges while fostering positive societal impacts through sustainable technological solutions.

BlueDot Photonics

Grant in 2021
BlueDot Photonics, Inc., based in Kirkland, Washington, specializes in the design, development, and production of solar panels and photonic devices. Founded in 2019, the company aims to significantly advance solar power deployment by reducing the cost of silicon solar panels by 10% while improving their efficiency by 16%. Additionally, BlueDot Photonics is focused on innovative manufacturing techniques to create flexible, lightweight solar modules with efficiencies exceeding 25%. By utilizing new semiconductor materials, the company enhances the performance and durability of solar panels, enabling customers to access affordable alternative energy solutions.
Discrete Lattice Industries develops programmable and cellular materials to reduce the need for fixed tooling. The company was founded in 2020 and is headquartered in Laguna Beach, California.

Mazdak International

Grant in 2021
Mazdak International is a capsule pipeline technology company that specializes in deep dredging.

GMJ Technologies

Grant in 2021
GMJ Technologies develops microanalytical technologies for biopharmaceutical and biomedical applications. The company was founded in 2018 and is headquartered in Seattle, Washington.
Dynamic Entropy Technology manufactures medical devices with the purpose of improving new technologies in the field of health sciences. The company was founded in 2018 and is headquartered in Pasco, Washington.

HaptX

Grant in 2020
HaptX develops advanced virtual reality gloves that simulate touch sensation with remarkable realism. By utilizing patented microfluidic technology, HaptX Gloves offer 130 points of touch feedback and provide resistive force feedback of 4 lbs. per finger while tracking hand motions with sub-millimeter precision. This innovative device creates a haptic experience that allows users to perceive the texture, shape, motion, vibration, and temperature of virtual objects, enhancing interaction within the virtual environment. Founded by Jake Rubin and Dr. Bob Crockett, HaptX operates with a team of 35 employees across offices in Seattle, Washington, and San Luis Obispo, California.

CircleIn

Grant in 2020
CircleIn is an online educational platform dedicated to enhancing the student study experience by fostering collaboration and accessibility. The platform enables students to connect with peers and high achievers nationwide for personalized coaching and support. By providing an easy-to-use app and website, CircleIn encourages students to work together to tackle challenging problems and share valuable study resources. The company's mission focuses on making learning more attainable and inclusive, ultimately aiming to unlock the full potential of every student.

Xonotiv

Grant in 2020
Xonotiv develops a prosthetic knee that will improve amputee mobility and safety while also allowing robots to walk like humans. The company's headquarters are in Auburn, Washington.

Membrion

Grant in 2020
Membrion, Inc. is a company based in Seattle, Washington, that specializes in the manufacture and commercialization of advanced membranes for filtering molecules. Founded in 2016 as a spin-out from the University of Washington, Membrion's technology is designed to operate under various challenging conditions, including extreme temperatures and pH levels, as well as in vacuum and biologically sensitive environments. The membranes are primarily utilized in applications such as flow batteries, water purification systems, fuel cells, and pharmaceuticals. The company has received financial support from numerous organizations, including the Murdock Charitable Trust and the National Science Foundation, which has facilitated its transition from research to commercial product. Membrion's innovative approach focuses on providing clients with durable and cost-effective membranes made from silica gel, contributing to improved efficiency in industrial wastewater treatment and other applications.

ThruWave

Grant in 2020
ThruWave specializes in millimeter wave imaging technology, catering to various commercial and industrial sectors such as robotics, construction, and quality control. Founded in 2017 and based in Seattle, Washington, the company offers low-cost sensors that leverage patent-pending radar signal processing and GPU-accelerated image reconstruction techniques. ThruWave's technology enhances operational efficiency by allowing construction professionals to visualize the internal structures of walls, ceilings, and floors, thereby reducing risks and expediting workflows. Additionally, its solutions support inventory verification, shipment confirmations, and detection of packaging issues, enabling clients to automate processes such as counting contents and identifying damaged or missing items.

A-Alpha Bio

Grant in 2020
A-Alpha Bio, Inc., founded in 2017 and based in Seattle, Washington, specializes in synthetic biology with a focus on drug development that targets multiple proteins. The company's flagship platform, AlphaSeq, offers innovative cell-based tools for quantitative and high-throughput measurement of protein interactions. This technology accelerates processes such as target discovery, library screening, and preclinical drug characterization, addressing significant bottlenecks in the industry. By providing biologics and molecular glue discovery and optimization services, A-Alpha Bio supports pharmaceutical companies in enhancing binding and specificity for various target proteins. The team comprises experts in synthetic biology, structural biology, and next-generation sequencing, all dedicated to advancing drug discovery methodologies.

ChameleonCloud

Grant in 2020
Cloud services have become ubiquitous to all major 21st century economic activities. However, cloud services and technologies can be significantly more powerful than they are now. A persistent barrier to further advancement has been the lack of a large-scale and open cloud research platforms. With funding from the National Science Foundation (NSF), the Chameleon project will provide such a large-scale platform to the open research community allowing them explore transformative concepts in deeply programmable cloud services, design, and core technologies. Chameleon will allow users to explore problems ranging from the creation of Software as a Service to kernel support for virtualization. This broad range of supported research includes many other areas such as developing Platforms as a Service, creating new and optimizing existing Infrastructure as a Service components, investigating software-defined networking, and optimizing virtualization technologies. The Chameleon testbed, will be deployed at the University of Chicago and the Texas Advanced Computing Center and will consist of 650 multi-core cloud nodes, 5PB of total disk space, and leverage 100 Gbps connection between the sites. While a large part of the testbed will consist of homogenous hardware to support large-scale experiments, a portion of it will support heterogeneous units allowing experimentation with high-memory, large-disk, low-power, GPU, and co-processor units. The project will also leverage existing FutureGrid hardware at the University of Chicago and the Texas Advanced Computing Center in its first year to provide a transition period for the existing FutureGrid community of experimental users. To support the broad range of experiments experiments described above, the project will support a graduated configuration system allowing full user configurability of the software stack, from provisioning of bare metal and network interconnects to delivery of fully functioning cloud environments. A special feature of Chameleon is that it provides for an exceptionally close integration of clouds and networks, which substantially enhances the capabilities of both. In addition, to facilitate experiments, Chameleon will support a set of services designed to meet researchers needs, including support for experimental management, reproducibility, and repositories of trace and workload data of production cloud workloads. The project is led by the Computation Institute at the University of Chicago and partners from the Texas Advanced Computing Center at the University of Texas at Austin, the International Center for Advanced Internet Research at Northwestern University, the Ohio State University, and University of Texas at San Antonio, comprising a highly qualified and experienced team. The team includes members from the NSF supported FutureGrid project and from the GENI community, both forerunners of the NSFCloud solicitation under which this project is funded. Chameleon will also form a set of partnerships with commercial and academic clouds, such as Rackspace, CERN and Open Science Data Cloud (OSDC), and will partner with other testbeds, notably GENI and INRIA's Grid'5000 testbed.

Docugami

Grant in 2020
Docugami, Inc. is an artificial intelligence document engineering company based in Kirkland, Washington, established in 2017. The company specializes in developing software-as-a-service (SaaS) solutions that utilize various AI techniques, such as natural language processing, image recognition, and declarative markup. These tools are designed to help businesses of all sizes enhance their document creation and management processes, leading to improved insight, efficiency, and overall business impact. Through its innovative approach, Docugami aims to transform how organizations handle their unique documents, making the process more effective and impactful.

Proteios Technology

Grant in 2020
Proteios Technology, founded in 2015 and based in Issaquah, Washington, focuses on providing cost-effective solutions for scientists involved in biopharmaceutical development. The company has developed a flexible protein technology that supports the discovery and efficient manufacturing of advanced therapeutics. Its offerings include a fully automated, closed system designed for the isolation of target immune cells, which complies with Current Good Manufacturing Practice for cell therapy manufacturing. Additionally, Proteios Technology provides kits for the purification of recombinant proteins and antibodies, utilizing proprietary affinity tags and silica-based resins. This enables researchers to quickly and economically isolate proteins of interest, facilitating the progression from preclinical discovery to the end-to-end manufacturing of autologous cell therapies.

A-Alpha Bio

Grant in 2020
A-Alpha Bio, Inc., founded in 2017 and based in Seattle, Washington, specializes in synthetic biology with a focus on drug development that targets multiple proteins. The company's flagship platform, AlphaSeq, offers innovative cell-based tools for quantitative and high-throughput measurement of protein interactions. This technology accelerates processes such as target discovery, library screening, and preclinical drug characterization, addressing significant bottlenecks in the industry. By providing biologics and molecular glue discovery and optimization services, A-Alpha Bio supports pharmaceutical companies in enhancing binding and specificity for various target proteins. The team comprises experts in synthetic biology, structural biology, and next-generation sequencing, all dedicated to advancing drug discovery methodologies.

Astrolabe Analytics

Grant in 2020
Developer of an analytics tool designed for partners across the battery value chain, from materials developers to systems integrators. The company offers a platform for battery data management and predictive analytics in fields such as automotive and electric vehicles, aerospace, grid storage, and much more, enabling clients to boost business outcomes, accelerate time-to-market, and drive better decision-making with customized options and insights.

Off Planet Research

Grant in 2020
Off Planet Research, founded in 2015 and based in Lacey, Washington, operates a facility dedicated to extraterrestrial research. The company specializes in creating environments that simulate conditions found on the Moon and other planetary bodies, which allows for the testing of space technology and the conduct of research and development. Off Planet Research provides high-quality simulants that replicate lunar regolith and ice, enabling researchers to design, adapt, and test components and processes for future lunar and off-world missions. This approach enhances mission assurance, improves cost-effectiveness, and accelerates the development of safe and effective space-based technologies.
Boydston Chemicals Innovations, Inc. manufactures resins and polymers. The company was founded in 2017 and is based in Federal Way, Washington. As of July 8, 2019, Boydston Chemicals Innovations, Inc. operates as a subsidiary of 3D Systems Corporation.

Opticyte

Grant in 2020
Opticyte, Inc, a medical device innovator developing proprietary advanced algorithms and tailored optical spectroscopy technology to measure and detect low oxygen levels in cells to prevent organ failure. Opticyte is developing the first Cell O2 Monitor for reducing organ failure. Founded in 2016, Opticyte, Inc, is a spinoff from the University of Washington. Headquartered in Seattle, WA, Opticyte employs engineering, regulatory, and communications teams with deep experience in bringing medical devices to market.

easyXAFS

Grant in 2019
easyXAFS offers complete instruments for advanced x-ray spectroscopy. The company was founded in 2015 and is headquartered in Seattle, Washington.
Developer of a self-aware system designed to protect the lives of national security, public safety, and private security personnel. The company's system consists of a series of small, ruggedized Artificial intelligence-powered sensors built into the grips of a firearm that monitor utilization at the edge and provide analytics and insights using instant notification, enabling clients to save lives and protect people.
Taproot Medical Technologies is a provider of biocompatible materials designed to apply this technology to medical device development.

Parse Biosciences

Grant in 2019
Parse Biosciences, based in Seattle, Washington, focuses on single-cell analysis and was incorporated in 2018. The company is dedicated to developing innovative technologies that enhance the understanding of cellular diversity and function at the single-cell level. By leveraging advanced methodologies, Parse Biosciences aims to provide researchers with powerful tools for exploring complex biological systems, ultimately advancing the fields of genomics and biomedical research.

ThermaWatts

Grant in 2019
ThermaWatts develops an ambient thermal electric converter that converts heat into electricity. The company is based in Renton, Washington.

Alertive Healthcare

Grant in 2019
Alertive Healthcare is a digital healthcare company focused on addressing hypertension and chronic diseases. Founded in 2017 and based in Seattle, Washington, the company provides a Bluetooth-enabled blood pressure monitoring device connected to a mobile application. This platform facilitates two-way communication between patients and their healthcare teams, allowing for remote monitoring and actionable treatment recommendations. Alertive Healthcare aims to significantly reduce the time required for patients to achieve blood pressure control, shortening the standard care duration of 18-24 months to as little as 10 weeks. By partnering with healthcare organizations, Alertive Healthcare enhances medication adherence and generates revenue for healthcare systems while tackling the hypertension epidemic.

Ocean

Grant in 2019
Eco-Shelter is a social enterprise founded in 2017 by Alexa Bednar, based in Seattle, Washington. The company focuses on providing safe and affordable roofing solutions for low-income households in India. It specializes in sustainable building materials, offering an eco-roof panel made from resin-coated bamboo mats. These panels are pressed and sealed to create a strong, lightweight, water-resistant, and flame-resistant roofing option. Through its innovative products, Eco-Shelter aims to improve living conditions for underprivileged communities by delivering accessible and environmentally friendly building solutions.

Sironix Renewables

Grant in 2019
Sironix Renewables, Inc. is a Seattle-based company founded in 2016 that specializes in producing environmentally friendly ingredients for cleaning and personal care products derived from plants. The company focuses on the development of oleo-furan surfactant technology, which enables the production of plant-based detergents with fewer harmful chemicals and higher effectiveness. Sironix Renewables aims to create safer consumer products, offering alternatives that are free from harmful additives. Additionally, the company’s innovations have potential applications in various industries, including agricultural pesticides and oil spill remediation, reflecting its commitment to sustainability and safety in industrial consumer products.
OtoNexus Medical Technologies Inc. specializes in the design, development, and commercialization of ultrasound medical devices for diagnosing middle ear infections, known as otitis media, in both children and adults. The company's innovative hand-held device enables clinicians to quickly and accurately distinguish between viral and bacterial infections, facilitating appropriate treatment decisions regarding antibiotic use. Utilizing ultrasound technology in a novel manner, the device offers rapid diagnostic results in seconds, making it user-friendly for both physicians and non-physician healthcare providers. Additionally, the incorporation of one-use-per-patient tips generates a recurring revenue stream for the company. Founded in 2010 and based in Seattle, Washington, OtoNexus Medical Technologies aims to improve the efficiency and accuracy of middle ear infection diagnosis.

Allumia

Grant in 2019
Allumia, LLC designs, funds, installs, and manages lighting upgrades. It evaluates the current lighting and follow-up with a proposal, which includes updated designs and expected savings; installs and upgrades the entire facility’s lighting; and provides replacement lamps, drivers, and additional lighting hardware; and maintenance services. The company serves commercial, athletic, automotive, and industrial markets. Allumia, LLC was founded in 2013 and is based in Seattle, Washington. It has additional satellite offices in Los Angeles, California and Durham, North Carolina.

Unanimous AI

Grant in 2019
Unanimous A.I., Inc. designs and develops swarm artificial intelligence-based software solutions. It offers Swarm AI, a solution that connects people online as real-time systems modeled after natural swarms enabling deeper insights and predictions; and Swarm Insight, a subscription service which builds and deploys intelligent swarms to provide predictive guidance for any application, including sales, marketing, product innovation, and finance. Unanimous A.I., Inc. was founded in 2014 and is based in San Francisco, California with additional offices in Arlington, Virginia; San Luis Obispo, California; Chicago, Illinois; and Washington, District of Columbia.

Conservation X Labs

Grant in 2019
Conservation X Labs focuses on harnessing technology and entrepreneurship to address the key drivers of human-induced extinction. By utilizing open innovation, the organization runs global innovation competitions that invite diverse participants to propose solutions aimed at conservation challenges. With a blend of in-house expertise and a commitment to scaling early-stage companies, Conservation X Labs aims to create impactful, market-driven solutions that tackle the root causes of extinction rather than merely addressing its symptoms. This approach, termed Conservation 3.0, emphasizes a transformative and interdisciplinary perspective on conservation efforts, positioning the organization at the forefront of environmental innovation.

Ultorg

Grant in 2019
Ultorg creates general-purpose software that helps organizations manage their data. Based on a new method for interactive data visualization, our product combines ease-of-use with expressive power to allow end-users to query, display, and edit relational data, without resorting to custom programming. This fills a long-standing gap between spreadsheets and tailor-made database applications.

GMJ Technologies

Grant in 2019
GMJ Technologies develops microanalytical technologies for biopharmaceutical and biomedical applications. The company was founded in 2018 and is headquartered in Seattle, Washington.

CircleIn

Grant in 2018
CircleIn is an online educational platform dedicated to enhancing the student study experience by fostering collaboration and accessibility. The platform enables students to connect with peers and high achievers nationwide for personalized coaching and support. By providing an easy-to-use app and website, CircleIn encourages students to work together to tackle challenging problems and share valuable study resources. The company's mission focuses on making learning more attainable and inclusive, ultimately aiming to unlock the full potential of every student.

Curio Interactive

Grant in 2018
Curio Interactive provides a variety of engaging online STEAM-based learning activities. The company is based in Seattle, Washington.

Stabilitas

Grant in 2018
Stabilitas Intelligence Communications, Inc. develops a platform which provide security and intelligence data. It provides data for security managers, intelligence teams, corporate protection teams, and travel managers. The company develops SigActs, a platform which provides information and context about risks around, and PACE Notify, a platform for communicating security data through SMS, voice, email, and application. The company was formerly known as A & H Stabilitas Ventures, Inc. Stabilitas Intelligence Communications, Inc. was incorporated in 2013 and is based in Seattle, Washington. As of August 11, 2020, Stabilitas Intelligence Communications, Inc. operates as a subsidiary of ONSOLVE, LLC.

Digital Promise

Grant in 2018
Digital Promise provides support to advance technologies that can transform teaching and learning. It is a non-profit organization originated by the U.S. Congress as part of the 2008 re-authorization of the higher education opportunity act. Digital Promise was founded in 2011 and is based in Washington, District of Columbia.

Beta Hatch

Grant in 2018
Beta Hatch grows insect protein for animal feed. Nutrient balanced fertilizer is a sterile by-product of their process. Beta Hatch knows bugs better than anyone- they use their expertise in entomology to grow the most efficient and nutritious insects. They are currently farming mealworms from their urban farm in Seattle. They believe in changing food systems. Their goal is to develop the technology and knowledge that will make insects the next commodity crop.

Emissol

Grant in 2018
Emissol is a company based in Mill Creek, Washington, specializing in the development of emission control technology aimed at reducing emissions from vehicles and other mobile sources. The company offers a range of services and capabilities, including engine and chassis-dynamometer testing, mobile emission measurements, innovative coating techniques, selective catalytic reduction, and gasoline particulate filters. Through these advanced technologies, Emissol enables its clients to contribute to a cleaner environment by effectively managing and minimizing harmful emissions.

Membrion

Grant in 2018
Membrion, Inc. is a company based in Seattle, Washington, that specializes in the manufacture and commercialization of advanced membranes for filtering molecules. Founded in 2016 as a spin-out from the University of Washington, Membrion's technology is designed to operate under various challenging conditions, including extreme temperatures and pH levels, as well as in vacuum and biologically sensitive environments. The membranes are primarily utilized in applications such as flow batteries, water purification systems, fuel cells, and pharmaceuticals. The company has received financial support from numerous organizations, including the Murdock Charitable Trust and the National Science Foundation, which has facilitated its transition from research to commercial product. Membrion's innovative approach focuses on providing clients with durable and cost-effective membranes made from silica gel, contributing to improved efficiency in industrial wastewater treatment and other applications.

Klar Scientific

Grant in 2018
Klar Scientific is a manufacturer specializing in spectroscopic microscopy through its patented confocal optical profile technology. The company produces the Klar Mini Pro microscope, which is a compact and affordable instrument tailored for researchers requiring spectral information with high spatial resolution. This microscope utilizes a laser to focus on samples, while a spectrometer collects the emitted light, allowing research laboratories to achieve clear visualizations through optical adjustments and magnification. Klar Scientific's innovations aim to enhance the capabilities of scientists in various research applications.

A-Alpha Bio

Grant in 2018
A-Alpha Bio, Inc., founded in 2017 and based in Seattle, Washington, specializes in synthetic biology with a focus on drug development that targets multiple proteins. The company's flagship platform, AlphaSeq, offers innovative cell-based tools for quantitative and high-throughput measurement of protein interactions. This technology accelerates processes such as target discovery, library screening, and preclinical drug characterization, addressing significant bottlenecks in the industry. By providing biologics and molecular glue discovery and optimization services, A-Alpha Bio supports pharmaceutical companies in enhancing binding and specificity for various target proteins. The team comprises experts in synthetic biology, structural biology, and next-generation sequencing, all dedicated to advancing drug discovery methodologies.

Xonotiv

Grant in 2018
Xonotiv develops a prosthetic knee that will improve amputee mobility and safety while also allowing robots to walk like humans. The company's headquarters are in Auburn, Washington.

JuneBrain

Grant in 2018
JuneBrain is an early start-up company that empowers multiple sclerosis patients through the power of telemedicine. It aims to develop a wearable and non-invasive imaging device that enables multiple sclerosis patients to monitor their disease activity at home, leading to earlier detection of MS attacks and improved monitoring of treatment efficacy. Its long-term goal is to extend the use of our device into the broader neurodegenerative disease population, thus creating a pathway towards more frequent, widely-accessible monitoring of brain health. ​It was founded in 2017 and is headquartered in Washington, DC.

Earshot (Application)

Grant in 2018
Developer of a AI and voice analysis application intended to provide feedback to teachers to help them improve. The company's application captures voice data from the classroom to provide real-time discussion analysis, enabling teachers to be able to quickly learn from their classrooms and improve their practice.

Plectica

Grant in 2018
Plectica LLC develops transdisciplinary science technology which visualizes and connects the information between people. It organizes and connects the ideas with visual maps which can be built together in real-time. The company provides a go-to tool for consultants and teachers who need to work with complex ideas, processes, and systems. Plectica LLC was formerly known as Systems Thinking Institute LLC. The company was founded in 2016 and is based in New York, New York.
Developer of a self-aware system designed to protect the lives of national security, public safety, and private security personnel. The company's system consists of a series of small, ruggedized Artificial intelligence-powered sensors built into the grips of a firearm that monitor utilization at the edge and provide analytics and insights using instant notification, enabling clients to save lives and protect people.

Proteios Technology

Grant in 2018
Proteios Technology, founded in 2015 and based in Issaquah, Washington, focuses on providing cost-effective solutions for scientists involved in biopharmaceutical development. The company has developed a flexible protein technology that supports the discovery and efficient manufacturing of advanced therapeutics. Its offerings include a fully automated, closed system designed for the isolation of target immune cells, which complies with Current Good Manufacturing Practice for cell therapy manufacturing. Additionally, Proteios Technology provides kits for the purification of recombinant proteins and antibodies, utilizing proprietary affinity tags and silica-based resins. This enables researchers to quickly and economically isolate proteins of interest, facilitating the progression from preclinical discovery to the end-to-end manufacturing of autologous cell therapies.

Vesicus

Grant in 2018
Vesicus is a roll-to-roll manufacturing process for nano cellular polymeric thin films. The company's technologies can tune the microstructure within the microcellular PET, imparting unique functional properties that are useful for a variety of applications.

Hive Battery Labs

Grant in 2018
Developer of a battery diagnostic technology designed to decrease capital and operation costs of lithium-ion battery manufacturing. The company offers test equipment and software analytics to expand the use of impedance spectroscopy, from battery management integrated circuits to high-power, multi-channel cyclers, enabling battery manufacturers to drive down the cost and improve the efficiency of formation, storage, and tests.

Jeeva

Grant in 2018
Jeeva Wireless Inc. is a Seattle-based company that specializes in developing transmission devices utilizing Wi-Fi, ZigBee, and Bluetooth technologies. Incorporated in 2015, Jeeva focuses on enhancing internet connectivity for a wide range of devices, aiming to support the growing demand for connectivity solutions among the next billion users. Through its innovative products, the company addresses the challenges of connecting more devices in an increasingly digital world.
Boydston Chemicals Innovations, Inc. manufactures resins and polymers. The company was founded in 2017 and is based in Federal Way, Washington. As of July 8, 2019, Boydston Chemicals Innovations, Inc. operates as a subsidiary of 3D Systems Corporation.

ThruWave

Grant in 2017
ThruWave specializes in millimeter wave imaging technology, catering to various commercial and industrial sectors such as robotics, construction, and quality control. Founded in 2017 and based in Seattle, Washington, the company offers low-cost sensors that leverage patent-pending radar signal processing and GPU-accelerated image reconstruction techniques. ThruWave's technology enhances operational efficiency by allowing construction professionals to visualize the internal structures of walls, ceilings, and floors, thereby reducing risks and expediting workflows. Additionally, its solutions support inventory verification, shipment confirmations, and detection of packaging issues, enabling clients to automate processes such as counting contents and identifying damaged or missing items.
Taproot Medical Technologies is a provider of biocompatible materials designed to apply this technology to medical device development.

Intentionet

Grant in 2017
Intentionet is a developer of management software that specializes in analyzing network configurations to identify and rectify errors. The company's software automates the testing of changes within both on-premises and cloud-based networks, proactively addressing potential issues that could lead to outages or security breaches. By providing clients with enhanced visibility into their network's security posture and connectivity, Intentionet facilitates rapid deployment and ongoing maintenance of network systems without the risk of service interruptions or compliance violations.

MicroHAOPs

Grant in 2017
MicroHAOPs is a Seattle-based company specializing in innovative wastewater treatment technology, founded in 2015. The company focuses on membrane-based treatment processes and has developed proprietary solutions that include a unique nanomaterial for membrane pre-treatment, wastewater treatment, and water purification. These advancements enable the effective removal of phosphorus from treated domestic wastewater and polluted natural waters to trace levels. By commercializing technology that minimizes fouling of water treatment membranes, MicroHAOPs supports businesses in reducing their freshwater costs and wastewater outputs, thereby enhancing their overall water sustainability.

Z-senz

Grant in 2017
Z-senz develops the next leap in LIDAR to enable safety and reliability in autonomous vehicles. The company's headquarters are in Washington, D.C. Founded in 2015 by a group of scientists with expertise in optics, lasers, material science, physics, and manufacturing,

LiloTree

Grant in 2017
LiloTree is an advanced materials company that offers next-generation technology solutions via chemistry and material innovations. The company is based in Seattle, Washington, and is an NSF-funded manufacturer and distributor of ENIG-Premium, an environmentally friendly patented solution that offers enhanced reliability at a lower cost.

Turntide

Grant in 2017
Turntide Technologies (formerly Software Motor Company) has developed an efficient and intelligent electric motor system. The revolutionary Smart Motor System is based on proven switched reluctance technology, now managed with advanced cloud software and connected to precise controls via IoT. Turntide’s vision is to eliminate the 25% of global electricity consumption that is wasted by legacy motors, thus accelerating the world’s transition from fossil fuels. Turntide is based in Sunnyvale, California, with offices in San Francisco; Arlington, Washington; and Kennesaw, Georgia. Turntide has installed Smart Motor Systems with dozens of customers, reducing their motor electricity consumption by an average of 64%, and is powering the systems of leading OEMs.

Mazdak International

Grant in 2017
Mazdak International is a capsule pipeline technology company that specializes in deep dredging.
OtoNexus Medical Technologies Inc. specializes in the design, development, and commercialization of ultrasound medical devices for diagnosing middle ear infections, known as otitis media, in both children and adults. The company's innovative hand-held device enables clinicians to quickly and accurately distinguish between viral and bacterial infections, facilitating appropriate treatment decisions regarding antibiotic use. Utilizing ultrasound technology in a novel manner, the device offers rapid diagnostic results in seconds, making it user-friendly for both physicians and non-physician healthcare providers. Additionally, the incorporation of one-use-per-patient tips generates a recurring revenue stream for the company. Founded in 2010 and based in Seattle, Washington, OtoNexus Medical Technologies aims to improve the efficiency and accuracy of middle ear infection diagnosis.

KONTAK, LLC

Grant in 2017
KONTAK, LLC specializes in advanced hydrogen storage technology aimed at making hydrogen accessible for mass-market applications, particularly in light- and heavy-duty fleet vehicles, as well as stationary power solutions. The company's innovative platform utilizes proprietary catalysts and precise reactor temperature control to facilitate the safe extraction of hydrogen from its carrier, ensuring durability across hundreds of cycles. This technology supports various hydrogen production methods, including steam methane reforming, biomass conversion, and renewable electrolysis from wind and solar sources. By focusing on affordability and ease of installation, KONTAK aims to lower the overall costs of hydrogen, making it a viable alternative for a wide range of users.

posed2, Inc.

Seed Round in 2017
posed2 is developing innovative, college-to-career planning and advising technologies using games and AI. We match prospective students with providers of post-secondary education and training based on the goodness of fit between an organization’s offerings and a student’s career goals. Once an applicant determines where they will apply to school, we help them design a course of study that makes it more likely they will graduate on-time and well prepared to enter the workforce.

RJS Biologics

Grant in 2017
Developer of novel cancer therapeutics and therapies designed to make cancer treatments more predictable. The company's services deliver beneficial therapeutics to patients suffering from cancer and other serious illnesses and also a novel drug conjugate approach that uses computationally designed affinity tags to drive therapeutic compounds into cancer cells and has a pipeline of conjugated anti-cancer compounds with payloads specific to a variety of clinically-relevant targets including kinase inhibitors, enzyme inhibitors, and cell cycle inhibitors, enabling patients to get proper treatment for cancer without any side effects

Misapplied Sciences

Grant in 2017
Misapplied Sciences is a mind-bending innovation that allows a hundred or more viewers to simultaneously share a digital display, sign, or light and each sees something different. The PARALLEL REALITY displays were invented by scientists, engineers, and designers with a history of transforming technology into amazing experiences. It was founded in 2014 and is based in Redmond, Washington.

Sironix Renewables

Grant in 2017
Sironix Renewables, Inc. is a Seattle-based company founded in 2016 that specializes in producing environmentally friendly ingredients for cleaning and personal care products derived from plants. The company focuses on the development of oleo-furan surfactant technology, which enables the production of plant-based detergents with fewer harmful chemicals and higher effectiveness. Sironix Renewables aims to create safer consumer products, offering alternatives that are free from harmful additives. Additionally, the company’s innovations have potential applications in various industries, including agricultural pesticides and oil spill remediation, reflecting its commitment to sustainability and safety in industrial consumer products.

PlayPosit

Grant in 2016
PlayPosit, Inc. operates an online learning platform that allows users to create and share interactive video lessons, transforming passive video content into engaging learning experiences. Founded in 2012 and based in Washington, D.C., PlayPosit serves both educational institutions and corporate clients, facilitating training for employees, partners, and customers. The platform supports various learning environments, including K-12, flipped classrooms, and blended learning settings. Users can enhance videos from sources such as TED and Khan Academy with interactive elements like quizzes, annotations, and peer reviews, enabling educators and trainers to monitor and assess learner engagement and understanding effectively. PlayPosit was previously known as eduCanon Inc. and rebranded in 2016. The company has received backing from notable organizations, including AT&T and Stanford’s startX, and has been recognized as a leading open educational resource.

Klar Scientific

Grant in 2016
Klar Scientific is a manufacturer specializing in spectroscopic microscopy through its patented confocal optical profile technology. The company produces the Klar Mini Pro microscope, which is a compact and affordable instrument tailored for researchers requiring spectral information with high spatial resolution. This microscope utilizes a laser to focus on samples, while a spectrometer collects the emitted light, allowing research laboratories to achieve clear visualizations through optical adjustments and magnification. Klar Scientific's innovations aim to enhance the capabilities of scientists in various research applications.

Workit Health

Grant in 2016
Workit Health, Inc. is a healthcare technology company that specializes in digital treatment for substance use disorders. Founded in 2014 and headquartered in Ann Arbor, Michigan, Workit Health offers an online platform that combines interactive therapeutic content with professional counseling services. The platform provides evidence-based treatment for opioid and alcohol use disorders, including medication-assisted treatment with buprenorphine. Users can access therapeutic recovery curriculums, video consultations with clinicians, online recovery groups, and virtual drug testing from the privacy of their homes. Workit Health serves a diverse range of clients, including employers, schools, hospitals, clinics, and recovery support communities, with additional locations in California, New Jersey, Alaska, and Washington.

Emissol

Grant in 2016
Emissol is a company based in Mill Creek, Washington, specializing in the development of emission control technology aimed at reducing emissions from vehicles and other mobile sources. The company offers a range of services and capabilities, including engine and chassis-dynamometer testing, mobile emission measurements, innovative coating techniques, selective catalytic reduction, and gasoline particulate filters. Through these advanced technologies, Emissol enables its clients to contribute to a cleaner environment by effectively managing and minimizing harmful emissions.

Beta Hatch

Grant in 2016
Beta Hatch grows insect protein for animal feed. Nutrient balanced fertilizer is a sterile by-product of their process. Beta Hatch knows bugs better than anyone- they use their expertise in entomology to grow the most efficient and nutritious insects. They are currently farming mealworms from their urban farm in Seattle. They believe in changing food systems. Their goal is to develop the technology and knowledge that will make insects the next commodity crop.

Strange Loop Games

Grant in 2016
Owner and operator of a gaming studio for developing educational games. The company owns and operates a gaming studio that specializes in developing multiplayer games where users aim at winning points and rewards by saving a virtual ecosystem, thereby teaching children the value of community and nature.

Membrion

Grant in 2016
Membrion, Inc. is a company based in Seattle, Washington, that specializes in the manufacture and commercialization of advanced membranes for filtering molecules. Founded in 2016 as a spin-out from the University of Washington, Membrion's technology is designed to operate under various challenging conditions, including extreme temperatures and pH levels, as well as in vacuum and biologically sensitive environments. The membranes are primarily utilized in applications such as flow batteries, water purification systems, fuel cells, and pharmaceuticals. The company has received financial support from numerous organizations, including the Murdock Charitable Trust and the National Science Foundation, which has facilitated its transition from research to commercial product. Membrion's innovative approach focuses on providing clients with durable and cost-effective membranes made from silica gel, contributing to improved efficiency in industrial wastewater treatment and other applications.

Phoresa

Grant in 2016
Phoresa develops clinical diagnostic tests to improve patient care by allowing physicians to make confident diagnoses without waiting days or weeks for test results. Our tests will lower costs for clinics, provide better patient management, and help reduce the spread and complication of diseases. ​

Earshot (Application)

Grant in 2016
Developer of a AI and voice analysis application intended to provide feedback to teachers to help them improve. The company's application captures voice data from the classroom to provide real-time discussion analysis, enabling teachers to be able to quickly learn from their classrooms and improve their practice.

Stabilitas

Grant in 2016
Stabilitas Intelligence Communications, Inc. develops a platform which provide security and intelligence data. It provides data for security managers, intelligence teams, corporate protection teams, and travel managers. The company develops SigActs, a platform which provides information and context about risks around, and PACE Notify, a platform for communicating security data through SMS, voice, email, and application. The company was formerly known as A & H Stabilitas Ventures, Inc. Stabilitas Intelligence Communications, Inc. was incorporated in 2013 and is based in Seattle, Washington. As of August 11, 2020, Stabilitas Intelligence Communications, Inc. operates as a subsidiary of ONSOLVE, LLC.

Intentionet

Grant in 2016
Intentionet is a developer of management software that specializes in analyzing network configurations to identify and rectify errors. The company's software automates the testing of changes within both on-premises and cloud-based networks, proactively addressing potential issues that could lead to outages or security breaches. By providing clients with enhanced visibility into their network's security posture and connectivity, Intentionet facilitates rapid deployment and ongoing maintenance of network systems without the risk of service interruptions or compliance violations.

Turntide

Grant in 2016
Turntide Technologies (formerly Software Motor Company) has developed an efficient and intelligent electric motor system. The revolutionary Smart Motor System is based on proven switched reluctance technology, now managed with advanced cloud software and connected to precise controls via IoT. Turntide’s vision is to eliminate the 25% of global electricity consumption that is wasted by legacy motors, thus accelerating the world’s transition from fossil fuels. Turntide is based in Sunnyvale, California, with offices in San Francisco; Arlington, Washington; and Kennesaw, Georgia. Turntide has installed Smart Motor Systems with dozens of customers, reducing their motor electricity consumption by an average of 64%, and is powering the systems of leading OEMs.

Hive Battery Labs

Grant in 2016
Developer of a battery diagnostic technology designed to decrease capital and operation costs of lithium-ion battery manufacturing. The company offers test equipment and software analytics to expand the use of impedance spectroscopy, from battery management integrated circuits to high-power, multi-channel cyclers, enabling battery manufacturers to drive down the cost and improve the efficiency of formation, storage, and tests.

LiloTree

Grant in 2016
LiloTree is an advanced materials company that offers next-generation technology solutions via chemistry and material innovations. The company is based in Seattle, Washington, and is an NSF-funded manufacturer and distributor of ENIG-Premium, an environmentally friendly patented solution that offers enhanced reliability at a lower cost.

Olis Robotics

Grant in 2016
Olis Robotics specializes in industrial telerobotic services designed to simplify robotic operations for its clients. The company offers software solutions that integrate two-dimensional and three-dimensional video fusion, allowing users to assist robotic automation with high-value tasks. Its technology features haptic guidance control and machine learning capabilities, enabling operators to intuitively manage complex robotic systems. This innovative approach enhances precision and efficiency in critical remote operations, allowing clients to focus more on achieving their objectives rather than on the intricacies of the robotic systems themselves. Through its patent-pending technology for force feedback, Olis Robotics promotes overall mission success across various industries.
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