National Science Foundation

Transparent Path is a technology provider specializing in supply chain visibility, particularly for the food industry. The company utilizes Internet of Things (IoT) sensors, edge computing, and artificial intelligence to create a secure and scalable platform that allows food manufacturers, processors, logistics partners, and retailers to monitor and manage supply chain issues in real-time. By offering both software and hardware solutions, Transparent Path enables its clients to gain insights into logistics, product quality, and risk management, helping them to detect and address problems before they escalate. This proactive approach not only enhances operational efficiency but also reduces costs and waste associated with perishable goods. Founded by Eric Weaver, who has extensive experience in enterprise transformation, Transparent Path aims to foster a more resilient and agile supply chain.

Rift Valley provides solutions for addressing burnout, turnover, and mental health disruption within the workplace. They provide management with a holistic dashboard and suite of tools. They are changing that model and offering institutions the means to prioritize their people effectively.

AccuBreath is a medical device company focused on creating an affordable and ultraportable ventilator designed for respiratory support. The company has developed a non-invasive ventilation and respiration monitoring system that offers gentle assistance to patients, particularly during sedation for medical procedures. This innovative ventilator helps to reduce airway obstruction, allowing healthcare professionals to maintain effective ventilation while minimizing potential complications, such as stomach inflation. AccuBreath aims to enhance patient care through its advanced respiratory technology, making high-quality respiratory support more accessible in various medical settings.

Eco-Shelter is a social enterprise founded in 2017 by Alexa Bednar, based in Seattle, Washington. The company focuses on providing safe and affordable roofing solutions for low-income households in India. It specializes in sustainable building materials, offering an eco-roof panel made from resin-coated bamboo mats. These panels are pressed and sealed to create a strong, lightweight, water-resistant, and flame-resistant roofing option. Through its innovative products, Eco-Shelter aims to improve living conditions for underprivileged communities by delivering accessible and environmentally friendly building solutions.

Stixfresh is focused on developing and commercializing groundbreaking and innovative technologies that will significantly reduce food waste via all-natural methods. Our first product, the Stixfresh stickers, have the potential to do just that. Stixfresh can reduce certain fresh fruit waste across the entire supply chain by extending their shelf-life, and keeping them fresher, longer. The Stixfresh technology, consists of an FDA-approved sticker that is coated with our patent-pending formulation, which is composed of 100% natural ingredients. The sticker is simply peeled and applied to the surface of certain fruits in order to extend its shelf-life by up-to 14 days. The formulation includes compounds that work together to create a protective layer around the fruit, which slows down the ripening process. Independent studies have shown that fruits treated with the Stixfresh sticker have increased sweetness, higher retention of moisture, and sustained cellular structure resulting in increased firmness.

Quadralynx specializes in the development of wearable biometric devices tailored for adults experiencing motor speech disorders, particularly those who face challenges with volume control due to Parkinson's disease and similar neurological conditions. The company's innovative device employs biofeedback technology to alert users through vibrations when their voice reaches a pathological state. By focusing on speech and voice improvement, Quadralynx aims to enhance the quality of life for individuals affected by these disorders.

Aspero Medical, Inc. is a medical device manufacturer based in Boulder, Colorado, established in 2018. The company specializes in gastrointestinal balloon endoscopy procedures, offering a product known as the AP Balloon Overtube. This innovative device utilizes pillar micro-texture technology to improve the performance of endoscopic procedures by enhancing mucosal wall traction and anchoring consistency within the gastrointestinal tract. By optimizing these aspects, Aspero Medical aims to reduce procedure time and sedation requirements, ultimately improving patient outcomes and providing cost-effective solutions for healthcare providers.

University of Colorado Boulder is a bold, innovative community of scholars and learners who accelerate human potential. University of Colorado Boulder, colloquially referred to as CU or Colorado, is a public research university in Boulder, Colorado. It is the flagship university of the University of Colorado system, and was founded in 1876, five months before Colorado became a state.

Medecipher is a highly innovative early stage company providing innovative solutions to help hospitals improve their operations.

Green Sun Medical, LLC is a medical device company established in 2013 and located in Fort Collins, Colorado. The company specializes in the design, development, and manufacturing of orthotic braces aimed at treating Adolescent Idiopathic Scoliosis (AIS) and Kyphosis. Its innovative products are designed to correct spinal deformities, providing support and alignment for patients with these conditions.

Developer of an online CAD tool intended to optimizes designs. The company's online CAD tool is accurate and enables self calibration, the performance control technology also enables devices to change their effective mass, damping, and stiffness on demand enabling students, researchers, and startups to facilitate a MEMS community of shared designs and compact models.

Skyhaven Systems is a specialty research and development firm that focuses on solving critical US Government needs in the Defense, Energy, Aerospace, and Environmental sectors. With the firm’s headquarters located in Steamboat Springs, CO and its main research and development laboratories located in Westford, MA, the firm applies advanced electrochemical engineering and science principles to solve technical problems of concern to the Government including the Department of Defense, NASA, Environmental Protection Agency, National Science Foundation, Department of Energy, USDA, NIH, and the Centers for Disease Control. Skyhaven Systems is a privately held limited liability company formed in 2017 that merged its former business, Reactive Innovations, LLC, into its new operations. The Firm owns a 4200 ft2 facility in Westford, MA where it conducts its primary research and development activities along with light manufacturing. Skyhaven conducts innovative research and development work in the chemical process technology area focusing on reaction chemistry, reactor design, separation systems, sensors, thermal management, and materials development. At the core of their technologies is a reaction-based chemical process used to fabricate the product, or that the product uses to conduct its operation. Skyhaven’s mission is to explore, develop, and commercialize novel chemical and electrochemical-based systems that larger organizations are disinterested in developing due to small market sizes, high risk, or lengthy development times that can be counter to meeting short-term profit margin goals. Skyhaven seeks out high risk development areas via responding to competitive solicitations and securing government funded contracts and grants. These contracts enable the firm to innovate and develop new technologies to solve government identified problems culminating in the delivery of research reports, operational prototypes, or a limited number of operational systems for use by the government. As a small business, Skyhaven owns the technology rights to its government funded research and development projects. The government receives a royalty-free license to use the technology for its needs while Skyhaven is free to commercialize the technology toward non-government needs. Consequently, the firm files patents and establishes trade secrets on select technologies to protect core development areas that are being primed for commercialization.

Map Collective specializes in developing an interactive mapping platform that utilizes artificial intelligence to analyze and visualize environmental data. This Software-as-a-Service solution integrates seamlessly with Geographic Information Systems (GIS) to provide users, including companies and governments, with essential tools for monitoring various environmental factors such as air quality, carbon footprints, and supply chain emissions. The platform facilitates traceability and emissions mapping, supports biodiversity assessments, aids in energy hub planning, and assists in transitioning to a circular economy. By offering a comprehensive view of the carbon impact on the environment, Map Collective empowers users to make informed decisions regarding sustainability and environmental management.

Contextualize provides the tools needed to capture the expertise spread across an organization and make it accessible and usable to others across the organization. It also leverages mathematical descriptions of complex phenomena and machine learning models to extract physics from the latter and models from the former, enabling clients to transform the wealth of information into actionable insights.

DrivenData focuses on leveraging data science and crowdsourcing to address significant social challenges. The company organizes online challenges, typically lasting 2-3 months, where a global community of data scientists competes to develop effective statistical models for complex predictive problems. In addition to these competitions, DrivenData offers services that include comprehensive data assessment, predictive modeling, statistical analysis, and rapid development and prototyping. By connecting mission-driven organizations with skilled data scientists, DrivenData aims to empower these organizations to make impactful decisions based on their data.

LumenAstra, founded in 2020 and headquartered in Longmont, Colorado, develops non-invasive, wearable deep-tissue temperature sensors aimed at enhancing patient care in various medical contexts. The company's innovative technology allows for the external measurement of internal temperature, making it particularly useful in cancer hyperthermia therapy. Additionally, LumenAstra's sensors have applications in monitoring hypothermia during aortic dissection repair, brain temperature in neonatal hypoxia-ischemia cases, and internal heat stress in military and hazardous environments. This technology enables medical professionals to effectively protect patients from serious injuries and fatalities related to heat stress.

Intersphere, founded in 2020 and headquartered in Fort Collins, Colorado, specializes in providing environmental services, focusing on weather and climate forecasts for seasonal to decadal planning horizons. The company employs a combination of artificial and human intelligence to deliver accurate predictions, helping clients manage risks related to weather and climate. Intersphere's services cater to various sectors, including natural resource management, energy, and agriculture, enabling clients to make informed decisions based on optimized forecasts.

Terra Cover is a monitoring platform operator based in Denver, Colorado, specializing in applications for insurance and water resource management. Founded in 2020, the company utilizes data, machine learning, and physics to provide insights into the Earth's constantly changing surface. Its platform enables businesses to analyze satellite imagery and geospatial data at scale, facilitating improved decision-making in resource management and risk assessment.

Grid7’s project, E-Blockchain: A Scalable Platform for Secure Energy Transactions and Control, aims to use blockchain technology to address power plant cybersecurity issues and explore how a decentralized approach can improve the reliability of energy networks.

JuneBrain is an early start-up company that empowers multiple sclerosis patients through the power of telemedicine. It aims to develop a wearable and non-invasive imaging device that enables multiple sclerosis patients to monitor their disease activity at home, leading to earlier detection of MS attacks and improved monitoring of treatment efficacy. Its long-term goal is to extend the use of our device into the broader neurodegenerative disease population, thus creating a pathway towards more frequent, widely-accessible monitoring of brain health. ​It was founded in 2017 and is headquartered in Washington, DC.

Recurrent Motors, Inc. specializes in analyzing electric vehicle (EV) batteries and providing detailed reports that assist car dealers and private buyers in purchasing used electric cars. Founded in 2020 and based in Seattle, Washington, the company offers tools that assess battery health, life expectancy, and current maximum range of EVs, addressing the complexities involved in understanding these factors as vehicles age. By delivering non-invasive tests and leveraging a national database of vehicle data and history, Recurrent enables informed decision-making for both dealers and consumers. Additionally, the company provides personalized monthly battery analyses for EV owners, enhancing their understanding of their vehicles' performance over time.

Current Surgical is a surgical device company that develops precise tools for the treatment of solid tumors. The company was founded in 2020 and has its headquarters in Washington, DC.

Immersive Reality Group, founded in 2004 and based in Bozeman, Montana, specializes in using artificial intelligence and virtual reality technology to deliver personalized healthcare solutions focused on mental health. The company operates a platform designed for stress and anxiety management, which integrates predictive analytics for health monitoring in a home setting. Through its innovative virtual reality experiences, Immersive Reality Group aims to provide users with real-time relief from stress and anxiety symptoms while also offering tools to develop effective coping strategies.

Wildlife Protection Management, Inc. manufactures a dart system for delivering vaccines and contraceptives on the horses. Its system also allows for the delivery of radio-frequency identification (RFID) chips for identifying each horse and monitoring the health and location. Wildlife Protection Management, Inc. was incorporated in 2018 and is based in Albuquerque, New Mexico.

CellDrop Biosciences, established in 2017 and based in Laramie, Wyoming, specializes in hydrogel-based technology for point-of-care diagnostics and targeted biomaterial delivery. The company focuses on developing hydrogel platforms that enable precise control over chemical and biological systems. Its innovations aim to facilitate the healing of equine musculoskeletal injuries efficiently, while also minimizing the risk of re-injury. By providing effective diagnostic and treatment solutions, CellDrop Biosciences addresses critical needs within the veterinary medical community.

Grapevine Health is a data-driven health media company focused on improving health literacy among underserved communities. By utilizing technical expertise and trusted communicators, the organization provides culturally appropriate health information that is both relatable and understandable. Their services assist health systems, insurers, and medical providers in enhancing community outreach and engagement, ensuring that health information is accessible and empowering for patients. Through empathetic storytelling and tailored communication strategies, Grapevine Health aims to democratize health information and support the maintenance of healthy behaviors within these communities.

SunFly Brands, Inc. develops invisible ink stamps/ultraviolet indicator stamps that a user wear underneath their sunscreen, which will saturate with color indicating when to reapply sunscreen. The company was incorporated in 2016 and is based in Seattle, Washington.

Nonlinear Materials Corp. is a developer of next-generation nano-scale photonics. Nonlinear Materials Corporation (NLM) has exclusively licensed proprietary materials and methods developed by University of Washington researchers to deliver “fiber-optic networks on a chip.”

Cobio Diagnostics is a biotechnology company that develops diagnostics for bacterial identification and phenotypic antibiotic resistance testing. The company was established in 2016 and is based in Golden, Colorado.

Vapor Cell Technologies, founded in 2020 and based in Boulder, Colorado, specializes in the development of ultra-compact vapor cells that achieve sub-nanometer precision in distance measurement. These innovative vapor cells convert lasers into wavelength standards, facilitating accurate measurements of length and optical frequency. By providing advanced sensing capabilities, the company supports various industries and laboratories in their efforts to advance atomic technology and enhance precision in scientific research and applications.

PainScan specializes in developing biomedical devices aimed at measuring and mapping pain intensity on a three-dimensional (3D) image of the human body. The company's innovative medical device incorporates ultrathin pressure sensors embedded in a clinician's glove, along with cameras that track palpation locations. By integrating data from various subjective and objective biosensors, the device allows for a detailed assessment of pain intensity at each palpation site. This technology enables clinicians to visualize pain comprehensively within the peripheral nervous system, enhancing their ability to diagnose and treat pain-related conditions.

Aquagga is a spinout company from the University of Alaska and the University of Washington, focused on developing innovative wet-waste treatment technology. The company utilizes supercritical water (sH2O) technology in conjunction with advanced additive manufacturing to effectively clean and desalinate various industrial effluents. By reducing environmental contaminants with lower energy consumption, Aquagga aims to provide significant social and environmental benefits. Its approach seeks to address pressing environmental challenges while fostering positive societal impacts through sustainable technological solutions.

ElectraSteel uses intermittent renewable energy for the electrification and decarbonization of iron and steelmaking. ElectraSteel's investors include leading sustainability-focused global venture capital funds with $300B+ assets under management.

CO2 Sync, founded in 2019 and based in Cody, Wyoming, specializes in the development of genomically optimized plants aimed at achieving specific desired traits. The company operates in stealth mode, focusing on innovative agricultural solutions to enhance plant performance and adaptability.

Molten Salt Solutions develops a technology platform to commercialize molten salt synthesis and purification technology. The company was founded in 2018 and is headquartered in Santa Fe, New Mexico.

BlueDot Photonics, Inc., based in Kirkland, Washington, specializes in the design, development, and production of solar panels and photonic devices. Founded in 2019, the company aims to significantly advance solar power deployment by reducing the cost of silicon solar panels by 10% while improving their efficiency by 16%. Additionally, BlueDot Photonics is focused on innovative manufacturing techniques to create flexible, lightweight solar modules with efficiencies exceeding 25%. By utilizing new semiconductor materials, the company enhances the performance and durability of solar panels, enabling customers to access affordable alternative energy solutions.

Mazdak International is a capsule pipeline technology company that specializes in deep dredging.

Discrete Lattice Industries develops programmable and cellular materials to reduce the need for fixed tooling. The company was founded in 2020 and is headquartered in Laguna Beach, California.

Progenitor MDX provides a comprehensive and customizable solution to manage COVID-19 infections from start to finish. We not only deliver testing results, but also help you develop actionable plans for infection management, providing reassurance to your communities.

GMJ Technologies develops microanalytical technologies for biopharmaceutical and biomedical applications. The company was founded in 2018 and is headquartered in Seattle, Washington.

FYR Diagnostics, founded in 2016 and based in Missoula, Montana, focuses on developing biomarker detection technology aimed at addressing chronic diseases in both human healthcare and agriculture. The company aims to tackle significant clinical challenges by commercializing innovative technologies that enhance the prediction, diagnosis, and management of diseases. This approach targets disorders that currently suffer from inadequate treatment and diagnostic options, thereby offering potential solutions for healthcare professionals and agricultural sectors facing substantial unmet needs.

Solving gout using engineered probiotics

Dynamic Entropy Technology manufactures medical devices with the purpose of improving new technologies in the field of health sciences. The company was founded in 2018 and is headquartered in Pasco, Washington.

HaptX develops advanced virtual reality gloves that simulate touch sensation with remarkable realism. By utilizing patented microfluidic technology, HaptX Gloves offer 130 points of touch feedback and provide resistive force feedback of 4 lbs. per finger while tracking hand motions with sub-millimeter precision. This innovative device creates a haptic experience that allows users to perceive the texture, shape, motion, vibration, and temperature of virtual objects, enhancing interaction within the virtual environment. Founded by Jake Rubin and Dr. Bob Crockett, HaptX operates with a team of 35 employees across offices in Seattle, Washington, and San Luis Obispo, California.

CircleIn is an online educational platform dedicated to enhancing the student study experience by fostering collaboration and accessibility. The platform enables students to connect with peers and high achievers nationwide for personalized coaching and support. By providing an easy-to-use app and website, CircleIn encourages students to work together to tackle challenging problems and share valuable study resources. The company's mission focuses on making learning more attainable and inclusive, ultimately aiming to unlock the full potential of every student.

Xonotiv develops a prosthetic knee that will improve amputee mobility and safety while also allowing robots to walk like humans. The company's headquarters are in Auburn, Washington.

Tortuga AgTech focuses on enhancing agricultural practices through the development of digital horticulture systems that integrate robotics, automation, precision data analytics, and machine learning. By automating labor-intensive tasks such as picking, packing, and trimming, Tortuga AgTech aims to significantly reduce the manual labor required in farming while increasing yields through optimized growing conditions. The company's mission is to promote a healthier society and a thriving ecosystem by empowering growers to produce unique, nutritious food that is environmentally sustainable. This approach not only helps farmers compete with large-scale agriculture but also fosters the creation of local technical jobs. Ultimately, Tortuga AgTech strives to provide fresher and healthier products to communities near their grower clients.

Membrion, Inc. is a company based in Seattle, Washington, that specializes in the manufacture and commercialization of advanced membranes for filtering molecules. Founded in 2016 as a spin-out from the University of Washington, Membrion's technology is designed to operate under various challenging conditions, including extreme temperatures and pH levels, as well as in vacuum and biologically sensitive environments. The membranes are primarily utilized in applications such as flow batteries, water purification systems, fuel cells, and pharmaceuticals. The company has received financial support from numerous organizations, including the Murdock Charitable Trust and the National Science Foundation, which has facilitated its transition from research to commercial product. Membrion's innovative approach focuses on providing clients with durable and cost-effective membranes made from silica gel, contributing to improved efficiency in industrial wastewater treatment and other applications.

Inherent Biosciences is a molecular diagnostics company that revolutionizes trial and error medicine and restore hope. The company does this by discovering what's inherent in our biology about the unexplained and translating discoveries into personal insights that inform actions. Inherent Biosciences develops medicines for treating pain, infertility, embryo quality, autism, rheumatoid arthritis, psoriatic arthritis, fetal heart disease, COVID-19, and many more.

Manufaturer of environmental sampling products intended to simplify the sample collection process. The company's system creates ultrasonic personal air sampler and water sampling products for environment analysis, enabling researchers and industrial hygienists to monitor particulates and pollutants in the work environment and perform fixed measurements within one device.

ThruWave specializes in millimeter wave imaging technology, catering to various commercial and industrial sectors such as robotics, construction, and quality control. Founded in 2017 and based in Seattle, Washington, the company offers low-cost sensors that leverage patent-pending radar signal processing and GPU-accelerated image reconstruction techniques. ThruWave's technology enhances operational efficiency by allowing construction professionals to visualize the internal structures of walls, ceilings, and floors, thereby reducing risks and expediting workflows. Additionally, its solutions support inventory verification, shipment confirmations, and detection of packaging issues, enabling clients to automate processes such as counting contents and identifying damaged or missing items.

Developer of a cloud-based SaaS platform designed to provide data relating to medical drug discovery. The company's software specializes in providing mass spectrometry data processing, analysis, reporting, and visualization for every instrument, molecule, algorithm, and workflow, allowing scientists to research and develop drugs and providing them with tools for spectrometry.

A-Alpha Bio, Inc., founded in 2017 and based in Seattle, Washington, specializes in synthetic biology with a focus on drug development that targets multiple proteins. The company's flagship platform, AlphaSeq, offers innovative cell-based tools for quantitative and high-throughput measurement of protein interactions. This technology accelerates processes such as target discovery, library screening, and preclinical drug characterization, addressing significant bottlenecks in the industry. By providing biologics and molecular glue discovery and optimization services, A-Alpha Bio supports pharmaceutical companies in enhancing binding and specificity for various target proteins. The team comprises experts in synthetic biology, structural biology, and next-generation sequencing, all dedicated to advancing drug discovery methodologies.

Aspero Medical, Inc. is a medical device manufacturer based in Boulder, Colorado, established in 2018. The company specializes in gastrointestinal balloon endoscopy procedures, offering a product known as the AP Balloon Overtube. This innovative device utilizes pillar micro-texture technology to improve the performance of endoscopic procedures by enhancing mucosal wall traction and anchoring consistency within the gastrointestinal tract. By optimizing these aspects, Aspero Medical aims to reduce procedure time and sedation requirements, ultimately improving patient outcomes and providing cost-effective solutions for healthcare providers.

Cloud services have become ubiquitous to all major 21st century economic activities. However, cloud services and technologies can be significantly more powerful than they are now. A persistent barrier to further advancement has been the lack of a large-scale and open cloud research platforms. With funding from the National Science Foundation (NSF), the Chameleon project will provide such a large-scale platform to the open research community allowing them explore transformative concepts in deeply programmable cloud services, design, and core technologies. Chameleon will allow users to explore problems ranging from the creation of Software as a Service to kernel support for virtualization. This broad range of supported research includes many other areas such as developing Platforms as a Service, creating new and optimizing existing Infrastructure as a Service components, investigating software-defined networking, and optimizing virtualization technologies. The Chameleon testbed, will be deployed at the University of Chicago and the Texas Advanced Computing Center and will consist of 650 multi-core cloud nodes, 5PB of total disk space, and leverage 100 Gbps connection between the sites. While a large part of the testbed will consist of homogenous hardware to support large-scale experiments, a portion of it will support heterogeneous units allowing experimentation with high-memory, large-disk, low-power, GPU, and co-processor units. The project will also leverage existing FutureGrid hardware at the University of Chicago and the Texas Advanced Computing Center in its first year to provide a transition period for the existing FutureGrid community of experimental users. To support the broad range of experiments experiments described above, the project will support a graduated configuration system allowing full user configurability of the software stack, from provisioning of bare metal and network interconnects to delivery of fully functioning cloud environments. A special feature of Chameleon is that it provides for an exceptionally close integration of clouds and networks, which substantially enhances the capabilities of both. In addition, to facilitate experiments, Chameleon will support a set of services designed to meet researchers needs, including support for experimental management, reproducibility, and repositories of trace and workload data of production cloud workloads. The project is led by the Computation Institute at the University of Chicago and partners from the Texas Advanced Computing Center at the University of Texas at Austin, the International Center for Advanced Internet Research at Northwestern University, the Ohio State University, and University of Texas at San Antonio, comprising a highly qualified and experienced team. The team includes members from the NSF supported FutureGrid project and from the GENI community, both forerunners of the NSFCloud solicitation under which this project is funded. Chameleon will also form a set of partnerships with commercial and academic clouds, such as Rackspace, CERN and Open Science Data Cloud (OSDC), and will partner with other testbeds, notably GENI and INRIA's Grid'5000 testbed.

Imagine a solution that understands an athlete’s life beyond their training. A solution that knows how many last-minute, unexpected work, family, and friends things can come up in a week. Imagine how happy coaches would be to free themselves from the manual work of inputting data and focus on the morale of their athletes instead.

Impressio is a manufacturer specializing in the development of ultra-dissipative materials designed to enhance human health and safety through innovative applications. The company focuses on creating advanced liner materials for protective equipment, such as helmet liners and padding, by utilizing liquid-crystal elastomers. These novel materials aim to address existing challenges in energy absorption associated with traditional helmet foams, thereby reducing the risk of concussions and improving head protection. Impressio's products have potential applications across various sectors, including sports, military, automotive, and aerospace.

Meati, also known as Emergy Foods, is a consumer goods company based in Boulder, Colorado, founded in 2016. The company specializes in producing whole muscle, nutritious plant-based meats designed to promote healthier lifestyles and environmental sustainability. By utilizing proprietary, clean technologies, Meati offers nutrient-dense meat alternatives that aim to appeal to a wide audience, ensuring that consumers can enjoy meals that are both good for their health and the planet.

Legov Systems Group, founded in 2018 and based in Boise, Idaho, specializes in the development of scalable power systems utilizing smart materials for energy harvesting. The company's innovative technologies are designed to recover significant amounts of low-grade waste heat from various sources, including combined heat and power installations, metal manufacturing, chemical processing, and industrial boilers. By enhancing the recovery of waste heat, Legov Systems Group enables its clients to lower operating costs, reduce energy demands, and improve overall sustainability in their operations.

Docugami, Inc. is an artificial intelligence document engineering company based in Kirkland, Washington, established in 2017. The company specializes in developing software-as-a-service (SaaS) solutions that utilize various AI techniques, such as natural language processing, image recognition, and declarative markup. These tools are designed to help businesses of all sizes enhance their document creation and management processes, leading to improved insight, efficiency, and overall business impact. Through its innovative approach, Docugami aims to transform how organizations handle their unique documents, making the process more effective and impactful.

Solving gout using engineered probiotics

Proteios Technology, founded in 2015 and based in Issaquah, Washington, focuses on providing cost-effective solutions for scientists involved in biopharmaceutical development. The company has developed a flexible protein technology that supports the discovery and efficient manufacturing of advanced therapeutics. Its offerings include a fully automated, closed system designed for the isolation of target immune cells, which complies with Current Good Manufacturing Practice for cell therapy manufacturing. Additionally, Proteios Technology provides kits for the purification of recombinant proteins and antibodies, utilizing proprietary affinity tags and silica-based resins. This enables researchers to quickly and economically isolate proteins of interest, facilitating the progression from preclinical discovery to the end-to-end manufacturing of autologous cell therapies.

A-Alpha Bio, Inc., founded in 2017 and based in Seattle, Washington, specializes in synthetic biology with a focus on drug development that targets multiple proteins. The company's flagship platform, AlphaSeq, offers innovative cell-based tools for quantitative and high-throughput measurement of protein interactions. This technology accelerates processes such as target discovery, library screening, and preclinical drug characterization, addressing significant bottlenecks in the industry. By providing biologics and molecular glue discovery and optimization services, A-Alpha Bio supports pharmaceutical companies in enhancing binding and specificity for various target proteins. The team comprises experts in synthetic biology, structural biology, and next-generation sequencing, all dedicated to advancing drug discovery methodologies.

Developer of an analytics tool designed for partners across the battery value chain, from materials developers to systems integrators. The company offers a platform for battery data management and predictive analytics in fields such as automotive and electric vehicles, aerospace, grid storage, and much more, enabling clients to boost business outcomes, accelerate time-to-market, and drive better decision-making with customized options and insights.

Optipulse, Inc. designs and manufactures wireless communication equipment for intercity and residential communication connection grid.

LightWorks Metrology, founded in 2019 and based in Holladay, Utah, specializes in the development of coordinate measuring machines and three-dimensional interferometer systems utilizing interferometry. The company aims to provide precision measurement solutions, enhancing accuracy in various applications. Its innovative approach combines advanced technology with a focus on quality, positioning LightWorks Metrology as a key player in the metrology sector.

Off Planet Research, founded in 2015 and based in Lacey, Washington, operates a facility dedicated to extraterrestrial research. The company specializes in creating environments that simulate conditions found on the Moon and other planetary bodies, which allows for the testing of space technology and the conduct of research and development. Off Planet Research provides high-quality simulants that replicate lunar regolith and ice, enabling researchers to design, adapt, and test components and processes for future lunar and off-world missions. This approach enhances mission assurance, improves cost-effectiveness, and accelerates the development of safe and effective space-based technologies.

Developer and manufacturer of aerosol particle collector devices designed to revolutionize the science of airborne particle sampling for physical, chemical and biological analysis. The company's collectors provide pre-concentrated samples, with better collection efficiency and offer efficient aerosol measurement capabilities that advance scientific knowledge, that lead to improving the environment, health, safety, and quality of life, enabling researchers to enhance their aerosol research with time-resolved and concentrated particle samples.

Biomimicry Design Alliance is a consulting organization that aims to make biomimicry more accessible to the architecture community. The company was founded in 2018 and is based in Denver, Colorado.

Boydston Chemicals Innovations, Inc. manufactures resins and polymers. The company was founded in 2017 and is based in Federal Way, Washington. As of July 8, 2019, Boydston Chemicals Innovations, Inc. operates as a subsidiary of 3D Systems Corporation.

Developer of a gastroesophageal reflux (GER) diagnostic tool designed for early detection and characterization of reflux events to guide treatment. The company's diagnostic tool uses ultrasound to non-invasively detect and characterize GER in a home setting, enabling patients to live a healthy life and reduce their suffering from gastrointestinal problems.

Opticyte, Inc, a medical device innovator developing proprietary advanced algorithms and tailored optical spectroscopy technology to measure and detect low oxygen levels in cells to prevent organ failure. Opticyte is developing the first Cell O2 Monitor for reducing organ failure. Founded in 2016, Opticyte, Inc, is a spinoff from the University of Washington. Headquartered in Seattle, WA, Opticyte employs engineering, regulatory, and communications teams with deep experience in bringing medical devices to market.

Provider of services in energy and materials science industry. The company provides technological services for solving technical issues in the field of energy and materials science. The company was incorporated in 2013 and is based in Highlands Ranch, Colorado.

ClearSight develops intraocular lenses for high-quality vision after cataract surgery. The company was founded in 2012 and is headquartered in Aurora, Colorado.

Grid7’s project, E-Blockchain: A Scalable Platform for Secure Energy Transactions and Control, aims to use blockchain technology to address power plant cybersecurity issues and explore how a decentralized approach can improve the reliability of energy networks.

nView Medical, Inc. is a medical technology company based in Salt Lake City, Utah, specializing in the development and manufacture of imaging equipment for invasive surgical procedures. Its flagship product, insta3D, utilizes advanced imaging technologies, including artificial intelligence and machine learning, to provide real-time, three-dimensional visual guidance during surgeries. This innovative approach enhances surgical accuracy and efficiency, allowing for quicker procedures while minimizing the use of X-ray radiation. nView's technology is applicable in various medical contexts, such as biopsies, tumor resections, minimally invasive vascular interventions, and orthopedic surgeries. Incorporated in 2012, nView Medical aims to improve surgical outcomes and patient safety through its cutting-edge imaging solutions.

XOnano's aim is to ensure the highest grade foam padding available. When standard foam is replaced with Xonano Smartfoam one can receive real-time feedback in anything from helmets to body armor. Not only does Xonano Smartfoam provide real-time feedback but it provides an extra level of protection.

Green Sun Medical, LLC is a medical device company established in 2013 and located in Fort Collins, Colorado. The company specializes in the design, development, and manufacturing of orthotic braces aimed at treating Adolescent Idiopathic Scoliosis (AIS) and Kyphosis. Its innovative products are designed to correct spinal deformities, providing support and alignment for patients with these conditions.

easyXAFS offers complete instruments for advanced x-ray spectroscopy. The company was founded in 2015 and is headquartered in Seattle, Washington.

Provider of a geospatial remote sensing and hydro spatial data service based in Denver, Colombia. The company provides hydro spatial products, Earth observation analysis services, and Satellite-Derived Bathymetry data for near-shore areas around the globe, enabling research and government agencies to run hydrographic surveys easily.

Developer of a self-aware system designed to protect the lives of national security, public safety, and private security personnel. The company's system consists of a series of small, ruggedized Artificial intelligence-powered sensors built into the grips of a firearm that monitor utilization at the edge and provide analytics and insights using instant notification, enabling clients to save lives and protect people.

Taproot Medical Technologies is a provider of biocompatible materials designed to apply this technology to medical device development.

Meati, also known as Emergy Foods, is a consumer goods company based in Boulder, Colorado, founded in 2016. The company specializes in producing whole muscle, nutritious plant-based meats designed to promote healthier lifestyles and environmental sustainability. By utilizing proprietary, clean technologies, Meati offers nutrient-dense meat alternatives that aim to appeal to a wide audience, ensuring that consumers can enjoy meals that are both good for their health and the planet.

Developer of a cloud-based SaaS platform designed to provide data relating to medical drug discovery. The company's software specializes in providing mass spectrometry data processing, analysis, reporting, and visualization for every instrument, molecule, algorithm, and workflow, allowing scientists to research and develop drugs and providing them with tools for spectrometry.

Roper provides ranchers with real-time decision support to optimize beef cattle health and productivity using a solar-powered, GPS-enabled health wearable and companion mobile app. GPS-steered tractors revolutionized farming and now we're using this same concept to revolutionize beef production. And we're taking it to the next level with health monitoring and predictive analytics, so ranchers can maximize herd fertility and nutrition, sustainably manage grazing, and pinpoint cattle that are sick or distressed.

Developer and manufacturer of aerosol particle collector devices designed to revolutionize the science of airborne particle sampling for physical, chemical and biological analysis. The company's collectors provide pre-concentrated samples, with better collection efficiency and offer efficient aerosol measurement capabilities that advance scientific knowledge, that lead to improving the environment, health, safety, and quality of life, enabling researchers to enhance their aerosol research with time-resolved and concentrated particle samples.

ThermaWatts develops an ambient thermal electric converter that converts heat into electricity. The company is based in Renton, Washington.

Parse Biosciences, based in Seattle, Washington, focuses on single-cell analysis and was incorporated in 2018. The company is dedicated to developing innovative technologies that enhance the understanding of cellular diversity and function at the single-cell level. By leveraging advanced methodologies, Parse Biosciences aims to provide researchers with powerful tools for exploring complex biological systems, ultimately advancing the fields of genomics and biomedical research.

Radiation Detection Solutions develops the solid-state tissue-equivalent detector, or SSTED, a radiation detection system. The company was founded in 2011 with its headquarters in Albuquerque, New Mexico.

Nielson Scientific develops custom UVC systems that produce precise and consistent UVC doses for industrial applications. The company is based in Lehi, Utah.

NeuDax offers a wide range of artificial intelligence (AI) solutions to upstream oil and gas (O&G) industry. The NeuDax "Analytics and Software-as-a-Service" (A+SaaS) solution provides both AI-Platforms and engineering and technical consults to clients to help them improve their decision making in the unconventional oil and gas projects. The NeuDax solution is beyond limited machine learning (ML) applications. We provide solutions based on cutting-edge technologies, including deep learning (DL) and reinforcement learning (RL), to maximize the advantage of big data to oil and gas operators.

Alertive Healthcare is a digital healthcare company focused on addressing hypertension and chronic diseases. Founded in 2017 and based in Seattle, Washington, the company provides a Bluetooth-enabled blood pressure monitoring device connected to a mobile application. This platform facilitates two-way communication between patients and their healthcare teams, allowing for remote monitoring and actionable treatment recommendations. Alertive Healthcare aims to significantly reduce the time required for patients to achieve blood pressure control, shortening the standard care duration of 18-24 months to as little as 10 weeks. By partnering with healthcare organizations, Alertive Healthcare enhances medication adherence and generates revenue for healthcare systems while tackling the hypertension epidemic.

Eco-Shelter is a social enterprise founded in 2017 by Alexa Bednar, based in Seattle, Washington. The company focuses on providing safe and affordable roofing solutions for low-income households in India. It specializes in sustainable building materials, offering an eco-roof panel made from resin-coated bamboo mats. These panels are pressed and sealed to create a strong, lightweight, water-resistant, and flame-resistant roofing option. Through its innovative products, Eco-Shelter aims to improve living conditions for underprivileged communities by delivering accessible and environmentally friendly building solutions.

Swift Solar Inc. is a U.S.-based company specializing in the design and manufacture of lightweight, flexible solar panels. Founded in 2017 and headquartered in San Carlos, California, with an additional facility in Golden, Colorado, the company focuses on advanced photovoltaic technology utilizing perovskite semiconductors. Swift Solar's products are engineered for diverse applications, including aerospace, automotive, and building sectors. The team comprises experts from prestigious institutions such as Stanford, MIT, and the University of Washington, who leverage their knowledge to develop innovative solar cell architectures and specialized manufacturing techniques. Swift Solar's ultra-thin perovskite films are designed for high efficiency, enabling the production of tandem solar cells that maximize light absorption and conversion efficiency while maintaining a low weight.

Medecipher is a highly innovative early stage company providing innovative solutions to help hospitals improve their operations.