National Science Foundation

The National Science Foundation (NSF), established in 1950 and located in Alexandria, Virginia, is an independent federal agency dedicated to advancing fundamental research and education across all scientific and engineering disciplines. With an annual budget of approximately $7.8 billion, the NSF operates America's Seed Fund, which allocates nearly $200 million each year to support startups and small businesses through the Small Business Innovation Research (SBIR) program. This initiative provides non-dilutive funding of up to $1.5 million to assist in research and development efforts, thereby facilitating the transformation of scientific discoveries into commercially viable products and services. By helping to de-risk technology, the NSF plays a crucial role in fostering innovation and addressing societal challenges through scientific advancements.

James Donlon

Program Director

Sean L. Jones

Assistant Director for Mathematical and Physical Sciences

Sethuraman Panchanathan

Director

Ben Schrag Ph.D

Program Director and Policy Liaison, SBIR / STTR

Past deals in New England

PneumoNIX

Grant in 2023
PneumoNIX Medical is developing gel-based technologies to prevent complications associated with percutaneous procedures such as soft tissue biopsies.
University of Massachusetts Amherst is a public research and land-grant university that offers academic, master's, and doctoral programs. It is the flagship campus of the University of Massachusetts system. University of Massachusetts Amherst has an annual enrollment of approximately 1,300 faculty members and more than 30,000 students.

Muon Vision

Grant in 2022
Our technology provides a passive, non-invasive X-ray imaging technology that can be used to i) visualize the percolation of process fluids across leaching heaps at scale; ii) monitor the stability of dams, heaps, mining assetts; iii) other industrial and minidng applications where density measurements are of key importance to improve safety and productivity.

T-Omega Wind

Grant in 2022
T-Omega Wind specializes in the development of innovative floating wind turbines aimed at enhancing offshore energy production. By utilizing a design that allows turbines to float on the water's surface, the company capitalizes on the natural movement of waves rather than resisting it. This approach improves stability and efficiency, as the rotor is securely held on both sides and aligns with the wind, adapting to changing weather conditions. T-Omega Wind's technology not only promotes the generation of affordable clean energy but also supports the expansion of sustainable energy solutions across the globe.

Landsdowne

Grant in 2022
Developer of an innovative button battery technology designed to deactivate batteries following accidental ingestion. The company is commercializing this technology for global companies seeking a turnkey, low-cost alternative to the growing button battery health crisis, enabling patients with fragile skin to remain unharmed.

The Emerald Tutu

Grant in 2022
The Emerald Tutu develops floating landscape infrastructure to mitigate the effects of climate change. The company provides waterfront amenities.

Singularity Energy

Grant in 2022
Singularity Energy, Inc. is a company that develops a platform for real-time energy and carbon management, aimed at helping corporate clients optimize their energy usage and reduce carbon emissions. Founded in 2018 and based in Cambridge, Massachusetts, the company utilizes artificial intelligence to incorporate real-time carbon dioxide signals from the energy grid into its management solutions. This innovative approach allows organizations to co-optimize their energy costs and emissions effectively. Singularity Energy's platform is designed to support climate regulators and sustainability professionals by providing transparent and reliable data, thereby enabling informed decision-making to meet rigorous environmental targets. By offering a modern alternative to traditional carbon reporting methods, the company contributes to the broader goal of grid decarbonization and promotes sustainable practices in various industries.

Arctura

Grant in 2022
Arctura is dedicated to securing a sustainable energy future that is affordable, healthy, and accessible. Through technology innovation, we are developing new wind energy solutions to get more from every turn.

Elateq

Grant in 2022
Elateq specializes in advanced electrochemical water treatment technology aimed at purifying wastewater. The company's innovative system employs low-level electricity and proprietary carbon materials to effectively remove various contaminants, including heavy metals, pathogens, and toxic chemicals. Elateq's solutions are tailored to meet the specific needs of different facilities, allowing for the efficient treatment of both municipal and industrial wastewater. By integrating these technologies, Elateq enhances the purification process and promotes cleaner water resources.

RaySecur

Grant in 2022
RaySecur Inc. specializes in advanced 3D package scanning technology designed to detect concealed and potentially dangerous items such as powders, solids, liquids, and various composite threats. Based in Cambridge, Massachusetts, the company offers the MailSecur system, which provides real-time 3D imaging capabilities that surpass traditional X-ray methods. Founded in 2018, RaySecur's innovative solutions utilize scalable terahertz scanners and millimeter-wave technology, allowing for the effective examination of suspicious letters, flat envelopes, and small parcels. Their devices are lightweight, portable, and user-friendly, requiring minimal training for mail screening. RaySecur's technology is employed by Fortune 500 companies and government organizations globally, enhancing security and safety for personnel and critical assets.

Lura Health

Grant in 2022
Lura Health is a company that specializes in developing tooth-mounted sensors designed to monitor oral health through saliva analysis. Founded in 2016 and based in Cambridge, Massachusetts, Lura Health's wireless intra-oral sensors allow users to continuously track key diagnostic metrics related to their oral environment. The sensors are designed to sit comfortably on a single tooth and monitor oral acidity, transmitting data to a mobile application. This technology provides users with meaningful insights and instant feedback, empowering them to take control of their health and improve personal health management by setting and achieving health goals.

UCHU Biosensors

Grant in 2022
UCHU Biosensors develops a platform of tooth mounted sensors to effortlessly track health through saliva.

futuresTHRIVE

Grant in 2022
FuturesTHRIVE develops an AI platform to identify and track pediatric mental health easily. FuturesTHRIVE's platform uses a combination of artificial intelligence, sentiment analysis, and machine learning to provide a mental health baseline that can be used by doctors and families to better understand a child's mental health qualities, thereby helping to identify mental health conditions in children easily and early.
University of Massachusetts (UMass) Dartmouth boasts challenging academics, particularly in the fields of Engineering, Law, Marine Science and Portuguese studies among others. One of the largest and most comprehensive Portuguese studies programs in the United States, this particular department offers specialized emphases in Portuguese Language and Literature and a doctorate in Luso-Afro-Brazilian Studies and Theory. The department also puts out its own publication and hosts conferences featuring scholars from around the globe. Since UMass Dartmouth’s Visual and Performing Arts Department is also one of its most respected, the campus abounds with theatre performance opportunities as well as student art galleries. Additionally, UMass has Business and Liberal Arts divisions as well as a division for the study of Education, Public Policy and Civic Engagement. Graduate programs are also available in a number of departments. Since UMass Dartmouth houses numerous research centers and institutes where scholarly conferences are held, the level of scholarship on campus is inspiring and stimulating. An application, transcripts, a personal essay and SAT scores are some of the materials prospective undergraduates will need to submit to admissions for consideration. Students who need assistance with paying tuition may apply for financial aid.

Boston Geospatial

Grant in 2021
Boston Geospatial, founded in 2019 and based in Boston, Massachusetts, focuses on developing a geospatial data platform that facilitates access to various satellite data providers. The platform allows users to search and compare a vast array of geospatial data, which can be analyzed in multiple ways. This capability is particularly beneficial for operators and risk managers in critical infrastructure sectors, as it enables them to obtain valuable geospatial insights essential for informed decision-making.

Alloy Enterprises

Grant in 2021
Alloy Enterprises Inc., based in Somerville, Massachusetts, specializes in developing 3D printing technologies aimed at addressing inefficiencies in traditional manufacturing processes. Incorporated in 2020, the company focuses on industrial engineering and manufacturing solutions, particularly in the production of aluminum components. Alloy Enterprises has created an innovative aluminum additive technology that allows for the production of dense and cost-effective parts without the use of expensive and hazardous powders. This advancement enables clients to overcome the limitations posed by conventional manufacturing methods, promoting innovation and facilitating progress in lightweight design and emissions reduction.

Akttyva Therapeutics

Grant in 2021
Akttyva Therapeutics focuses on developing targeted therapeutics aimed at addressing cell barrier dysfunction, particularly in vascular barrier disorders. The company leverages its understanding of biological pathways, along with artificial intelligence and machine learning, to design innovative treatments. By concentrating on the structural aspects of cell barriers, Akttyva Therapeutics aims to provide solutions that enable healthcare professionals to effectively manage various medical conditions related to cell barrier dysfunction.

Gencores

Grant in 2021
Gencores provides a platform that reduces the risk of concussion with customizable, smart, shock-absorbing helmet inserts.

Clairways

Grant in 2021
Clairways specializes in smart lung monitoring technology designed for pharmaceutical clinical trials. The company develops a wearable digital lung monitor that captures critical respiratory metrics for individuals suffering from conditions such as asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis (CF). Fitted to the body, this device employs acoustic sensors and machine learning technology to detect and characterize various respiratory metrics. The collected data is presented in an accessible format, allowing healthcare providers to easily monitor and assess patients' respiratory health over the long term.

Supranational

Grant in 2021
Supranational develops hardware and software solutions for verifiable and secure computing. The company was founded in 2019 with the goal of developing products at the intersection of cryptography and computer architecture.

Labby

Grant in 2021
Labby Inc. is a technology company based in Cambridge, Massachusetts, founded in 2017. It specializes in developing a smartphone-based wireless optical spectrometer for testing milk composition, primarily serving farmers and dairy processors. The company's AI-driven cloud platform translates raw optical data into actionable insights for individual animals and entire herds, facilitating rapid mastitis detection and timely intervention. In addition to its primary focus on dairy, Labby's technology has applications in the beer and wine production industry, offering tools for counterfeit detection, quality control, and serving as a virtual brewmate for homebrewers. The platform also aids in monitoring spoilage along the supply chain, detecting adulterants and contamination, and tracking harvest cycles while providing meteorological data mapping for farm-level analytics.

Biko Biolabs

Grant in 2021
Biko Biolabs is a research company founded in 2020 and located in Somerville, Massachusetts, that focuses on the intersection of plastic waste and regenerative agriculture. The company aims to address research and development gaps related to sustainability and self-sufficiency in traditionally marginalized communities. By providing resources to innovators, Biko Biolabs fosters the creation of new economic opportunities and trains emerging local scientists and engineers. The company emphasizes impactful research that is closely aligned with the specific needs of the communities involved, enabling tailored scientific practices and technologies that directly address fundamental community challenges.

BirdHabitatBot

Grant in 2021
BirdHabitatBot develops a robotic system to remove invasive plant species from the environment. Unpiloted aerial systems images from the company's drones are used to map, monitor, and remove non-native invasive plants in the deciduous forest that are significantly contributing to the degradation of forest habitat, allowing natural resource professionals to manage understory invasive shrub species and improve habitat for native plants and wildlife.

Skyhaven Systems

Grant in 2021
Skyhaven Systems is a specialty research and development firm that focuses on solving critical US Government needs in the Defense, Energy, Aerospace, and Environmental sectors. With the firm’s headquarters located in Steamboat Springs, CO and its main research and development laboratories located in Westford, MA, the firm applies advanced electrochemical engineering and science principles to solve technical problems of concern to the Government including the Department of Defense, NASA, Environmental Protection Agency, National Science Foundation, Department of Energy, USDA, NIH, and the Centers for Disease Control. Skyhaven Systems is a privately held limited liability company formed in 2017 that merged its former business, Reactive Innovations, LLC, into its new operations. The Firm owns a 4200 ft2 facility in Westford, MA where it conducts its primary research and development activities along with light manufacturing. Skyhaven conducts innovative research and development work in the chemical process technology area focusing on reaction chemistry, reactor design, separation systems, sensors, thermal management, and materials development. At the core of their technologies is a reaction-based chemical process used to fabricate the product, or that the product uses to conduct its operation. Skyhaven’s mission is to explore, develop, and commercialize novel chemical and electrochemical-based systems that larger organizations are disinterested in developing due to small market sizes, high risk, or lengthy development times that can be counter to meeting short-term profit margin goals. Skyhaven seeks out high risk development areas via responding to competitive solicitations and securing government funded contracts and grants. These contracts enable the firm to innovate and develop new technologies to solve government identified problems culminating in the delivery of research reports, operational prototypes, or a limited number of operational systems for use by the government. As a small business, Skyhaven owns the technology rights to its government funded research and development projects. The government receives a royalty-free license to use the technology for its needs while Skyhaven is free to commercialize the technology toward non-government needs. Consequently, the firm files patents and establishes trade secrets on select technologies to protect core development areas that are being primed for commercialization.

KovaDx

Grant in 2021
KovaDx focuses on improving healthcare access for individuals suffering from Sickle Cell Disease and other hemolytic anemias through an innovative point-of-care solution. The company has developed a health monitoring tool that utilizes Quantitative Phase Imaging and deep learning technology to provide affordable and easy-to-use diagnostics. This system is designed to bridge gaps in care for blood diseases, enabling better management of blood health. By offering a diagnostic and monitoring device, KovaDx aims to enhance the understanding of treatment impacts and improve patient outcomes. Ultimately, the company seeks to support individuals with Sickle Cell Disease in enhancing their overall prognosis and quality of life.

BioSens8

Grant in 2021
BioSense8 develops biosensors for use in human and animal healthcare, and environmental wellness. The company was founded in 2020 and is headquartered in Boston, Massachusetts.

MedChem Partners

Grant in 2021
MedChem Partners is a medicinal chemistry CRO that specializes in developing small molecule therapeutics. The company was founded in 2006 and is headquartered in Lexington, Massachusetts.

Tender Food

Grant in 2021
Boston Meats, Inc. produces alternative meat products using proteins. It also develops fiber production technology to produce meats using natural proteins. The company was founded in 2020 and is based in Somerville, Massachusetts.

Theromics

Grant in 2021
Theromics Inc. develops cell therapies. It offers HeatSYNC Gel, a thermal accelerant (TA) that augments MW and RF energy by increasing local tissue electrical conductivity in a reproducible and effective manner. The company’s TA absorbs microwave energy effectively preventing heat loss caused by blood flow in large vessels adjacent to ablation zone; optimizes the shape of the ablation zone into a circle making the ablation volume predictable; and produces a larger ablation area making it easier to target the tumor center and with 3-D modeling optimizes antenna guidance into tumor mass. Theromics Inc. was founded in 2016 and is based in West Bridgewater, Massachusetts.

Stellate DNA

Grant in 2021
Stellate DNA, founded in 2020 and headquartered in Cambridge, Massachusetts, specializes in developing proprietary DNA donor technology for the synthesis and production of single-strand DNA donors. The company employs a clonal synthesis approach rather than traditional chemical methods, allowing for the manufacture of customizable gene knock-in payloads. This platform enables production at microgram to milligram scales while maintaining controlled costs, thereby assisting medical professionals in achieving minimal mutation rates and ensuring sequence uniformity.

EnVision Endoscopy

Grant in 2021
Developer of a medical device designed to use for endoscopic surgeries. The company's device is compatible with standard endoscopes for tissue approximation for surgeries with an image-guided suturing system, enabling hospitals to reduce the procedure time and mortality rates.

Simpact

Grant in 2021
Simpact develops analytics and forecasting software to help businesses make data-driven decisions. The company's headquarters are in Boston, Massachusetts.

Bryant University

Grant in 2021
Bryant University, founded in 1863 and located in Smithfield, Rhode Island, is a non-profit institution that offers a diverse array of academic programs through its College of Business Administration and College of Arts and Sciences. The university is committed to providing innovative education that meets the evolving needs of industry and society, focusing on developing students into effective leaders of character. Its curriculum emphasizes real-world application and a global perspective, supported by various co-curricular opportunities such as internships, service-learning programs, and practicums. With a strong student-centered community, Bryant University fosters an environment where students can enhance their leadership skills while engaging in practical experiences. The university has a robust alumni network of over 40,000 graduates who contribute positively to their professions and communities worldwide.

Riff Analytics

Grant in 2021
Riff Learning Inc is a company that specializes in developing artificial intelligence-based tools aimed at enhancing communication in virtual environments. Founded in 2017 and headquartered in Newton, Massachusetts, Riff offers a platform that analyzes vocal data from video meetings and text chats to assess individual and team dynamics. Its technology measures interaction patterns, providing insights into engagement, influence, and information flow among participants. The Riff Platform delivers both real-time and post-meeting feedback, allowing users to become more aware of their communication styles and how these affect their colleagues. Emphasizing privacy, Riff ensures that the data collected is only accessible to the individuals involved, maintaining confidentiality and never sharing information with advertisers or for sale.

Heila Technologies

Grant in 2021
Heila Technologies is an MIT-born startup dedicated to simplifying the integration and operation of individual Distributed Energy Resources (DERs) and microgrids. It is focused on the commercialization of the Heila IQ Platform, a decentralized optimization system that reduces system complexity and cost. The company was founded in 2017 and is based in Somerville, Massachusetts.
Irradiant Technologies develops implosion fabrication lithography for chemically amplified high throughput micro-fabrication. The company was founded in 2020 and is headquartered in Cambridge, Massachusetts.

Marley Environmental

Grant in 2021
Marley Environmental offers consulting, engineering, and technical services to a diverse range of clients, including contractors and government entities. The company specializes in ASTM property site assessments and field investigations, which support owners and developers in their community development projects. By adhering to international standards, Marley Environmental ensures the delivery of high-quality engineering consultancy, facilitating informed decision-making for its clients in various industrial and commercial sectors.

AeroShield

Grant in 2021
AeroShield manufactures a super-insulating, nanoporous form of glass for energy efficient windows. The AeroShield material can be placed between two panes of glass, similar to a traditional double-pane, to create a product that is 50% more insulating than traditional windows, but with a payback period up to 5 times faster than windows of similar performance.

Jet-Set Offset

Grant in 2021
Jet-Set Offset is a donation-based carbon-offsetting tool for air travel, and a consumer-friendly alternative to the traditional carbon marketplace. Our site operates as a fundraising tool for environmental nonprofit organizations and facilitates automatic, mileage-based donations from travelers' flights. We've developed this approach to raise awareness of the environmental impact of air travel and inspire eco-conscious travelers and businesses to take action. Travelers and companies can subscribe to Jet-Set Offset and choose to support a nonprofit organization automatically with a one cent-per-mile donation every time they, or their employees, fly. Our nonprofit partners are working towards local climate solutions across the country, operating certified carbon offset and credit projects, as well as advocacy, education, renewable energy, reforestation, and/or conservation programs.

RevMedica

Grant in 2021
Manufacturer of surgical devices intended to enhance surgeon performance. The company's system provides critical decision-making information along with superior performance and a smart balance of features and ease the way surgeons approach soft tissue management, enabling surgeons to extend their tactile reach to the target tissue with AI guidance, minimize inefficient workflows, reduce costs, and eliminate toxic waste disposal.

FluidForm Bio

Grant in 2021
FluidForm is a provider of 3D bioprinting services to build the additive manufacturing platform for 3D printing silicone and 3D bioprinting. The company's FRESH technology enables the printing of silicones, urethanes, epoxies, liquid metals, biologic materials, and more, revolutionizing diverse fields, from aerospace to wearable sensors to regenerative medicine. FluidForm was founded in 2018 and is headquartered in, Acton, MA.

Aliro Security

Grant in 2021
Aliro Technologies, Inc. develops and offers cloud based software-as-a-service platform for coding in quantum environment. The company's platform enables coders with hardware-independent toolkit for developers of quantum algorithms and applications to be used in quantum computers. Aliro Technologies, Inc. was founded in 2019 and is headquartered in Boston, Massachusetts.

Silartek

Grant in 2021
SilarTek develops solar silicon technology with the aim of producing solar panels more accessible to a wider audience. The company was founded in 2020 and is based in Leominster, Massachusetts.

Enable Therapeutics

Grant in 2021
Enable Therapeutics is a biotechnology company developing a patented drug delivery platform. The company was founded in 2020 and is headquartered in Hopedale, Massachusetts.

SiTration

Grant in 2021
SiTration, founded by Brendan Smith in 2020 and based in Cambridge, Massachusetts, specializes in the development of ultra-durable filtration membranes tailored for efficient separations in harsh environments. The company's innovative technology enhances energy efficiency in challenging industrial applications by integrating the low cost and exceptional durability of various advanced commercial membranes. This enables users to achieve resource-efficient operations even in demanding conditions, setting SiTration apart in the filtration industry.

Nabla Bio

Grant in 2021
Nabla is an autoreverse platform that enables the rapid discovery of previously unattainable protein variants with supernatural qualities.Nabla Bio makes new medicines and improve nutrition by engineering novel proteins.

Spatio Metrics

Grant in 2021
Spatio Metrics presents architecture as a new tool for advancing health by filling the gap between design, data, and performance. The company helps hospitals manage facilities with a dashboard that shows how spaces influences patients’ health outcomes. The company's product analyzes floor plans, reveals design gaps, and recommends performance improvements. Hospital administrators are encouraged to make smarter design investments by quantifying the human and financial impact of design.

Sperry Bio

Corporate Round in 2021
Sperry Bio provides the sperry micro-coring system, which is a medical device and has not been evaluated for marketing clearance. They address current prioritized objectives of regenerative skin medicine research programs within the army medical research and materiel command clinical and rehabilitative medicine research program.
Aura Intelligent Systems provides solutions in the fields of radio technology, robotics, and artificial intelligence.​ Its patented technology provides 5D situational awareness without the harmful effects of interference, jamming, and multipath. Their technology is based on a 5G hardware architecture and intelligent software that can be programmed.

Spero Therapeutics

Grant in 2021
Spero Therapeutics, a clinical-stage biopharmaceutical company based in Cambridge, Massachusetts, specializes in developing novel therapies for multi-drug resistant (MDR) bacterial infections and rare diseases. Its key product candidates include tebipenem pivoxil hydrobromide, an oral carbapenem-class antibiotic intended for adults with MDR Gram-negative infections, and SPR206, an intravenous agent targeting MDR Gram-negative infections in hospital settings. Additionally, the company is advancing SPR720, an oral antibiotic designed for treating pulmonary non-tuberculous mycobacterial disease. Spero Therapeutics has established various collaborations and license agreements to support the development and commercialization of its products, including partnerships with Meiji Seika Pharma, Everest Medicines, and the Bill & Melinda Gates Medical Research Institute. Founded in 2013, Spero aims to address the critical need for effective treatments against serious bacterial infections using innovative approaches and mechanisms.

Flux Marine

Grant in 2021
Flux Marine specializes in developing electric marine propulsion systems designed to enhance performance while minimizing environmental impact. The company focuses on creating electric boat motors that utilize solid-state components to achieve zero emissions, thereby reducing pollution in marine environments. By prioritizing efficiency and sustainability, Flux Marine's motors not only enhance transport capabilities but also significantly lower noise and air pollution. Additionally, these propulsion systems are virtually maintenance-free, contributing to a reduced carbon footprint and promoting cleaner practices within the marine industry.

Verdox

Grant in 2021
Verdox is dedicated to reversing climate change through the development and deployment of advanced technology. The company’s proprietary electro-swing process, developed at MIT, enables carbon dioxide and other acid gases to be captured with up to 80% less energy and 70% less cost than conventional approaches.

GreenSight

Grant in 2021
GreenSight Agronomics, Inc. is a company that develops advanced drone technology and a cloud-based platform aimed at improving agricultural and turf management. Founded in 2015 and headquartered in Brookline, Massachusetts, GreenSight manufactures automated drones equipped with sophisticated sensors and data analytics capabilities. Its offerings include services for turf monitoring, crop management, irrigation, and pest detection. The company provides actionable insights through its drone technology, which allows land managers in sectors such as agriculture, energy, and construction to gather daily aerial intelligence efficiently. Notably, GreenSight's solutions have been designed to significantly reduce water and chemical usage, thereby saving costs and enhancing sustainability for golf courses and farms. By detecting plant stress and diseases early, the platform enables timely intervention by agrochemical companies, ultimately improving crop health and operational efficiency.

Vaxess Technologies

Grant in 2021
Vaxess Technologies, Inc. is a biotechnology company based in Boston, Massachusetts, founded in 2011. It specializes in developing and commercializing silk biomaterial technologies aimed at improving vaccine delivery and storage. The company has created the MIMIX microneedle platform, which facilitates transdermal delivery of vaccines and therapies, and the MATRIX formulation and drying platform, which enhances the stability of vaccines, therapeutics, and diagnostic products. By utilizing a silk-derived protein, Vaxess enables vaccines to be stored and transported without refrigeration, thereby reducing distribution costs and increasing access to essential healthcare products globally.
Ernest Pharmaceuticals is a biotechnology company based in Hadley, Massachusetts, founded in 2016. The company specializes in developing innovative bacterial therapeutics aimed at treating cancer. Its unique approach involves programming bacteria to deliver intracellular macromolecules directly into tumor tissues. These engineered bacteria are motile, allowing them to actively penetrate and target metastatic diseases and inoperable tumors. Through these advancements, Ernest Pharmaceuticals aims to enhance treatment options for patients facing challenging cancer diagnoses.
Millimeter Wave Systems, founded in 2016 and headquartered in Amherst, Massachusetts, specializes in millimeter wave and microwave hardware solutions. The company develops a range of products, including subsystems, modules, components, and antennas, as well as advanced technologies such as cryogenic quantum-limited parametric amplifiers and latching junction ferrite circulators. These innovations are utilized in various applications, including medical scanners, sensors, automobile radars, and high data-rate communications. Millimeter Wave Systems aims to provide consistent quality in production while offering customizable solutions tailored to specific industry needs.

Ubiros

Grant in 2020
Manufacturer of a robotic gripper designed to handle fragile objects without damaging them. The company's pneumatic system consists of polyurethane and polyurethane fingers which provide precise control over gripping force and movement, enabling non-traditional industries to automate material handling activities.

Thinking Robots

Grant in 2020
Thinking Robots provides software solutions for robotic tasks that can be performed on any robotic platform. The company was founded in 2010 and is headquartered in Boston, Massachusetts.

Fortify

Grant in 2020
Fortify is a Boston-based advanced manufacturing company that specializes in designing and producing custom composite materials using a patented magnetic 3D printing technology. Founded in 2016, the company focuses on creating high-performance products reinforced with carbon fiber, fiberglass, and ceramics. Fortify's innovative approach aims to transform the additive manufacturing landscape by offering optimized composite materials suitable for a variety of applications, including tool manufacturing, aerospace, and automotive industries. With a commitment to affordability and customization, Fortify is positioned to lead advancements in the production of reinforced composite products.
Worcester Polytechnic Institute (WPI), founded in 1865, is a non-profit educational institution located in the United States. It provides a diverse range of undergraduate and graduate programs, including fields such as computer science, chemical engineering, psychology, and business administration. WPI is known for its distinguished faculty, advanced research facilities, and an active community that fosters collaboration and innovation. The institute emphasizes a hands-on approach to learning, encouraging students to engage in real-world problem-solving and make meaningful contributions to society.
Circadian Positioning Systems specializes in circadian-targeted technology aimed at enhancing performance in critical work environments. The company develops innovative solutions that incorporate wearable sensors and circadian-based light interventions. These technologies are designed to adjust an individual's circadian rhythm, promoting optimal physical and mental performance during work hours and improving sleep quality during designated rest periods. By addressing the effects of tiredness and fatigue, Circadian Positioning Systems enables users to maintain high levels of productivity and well-being in demanding situations.

Omnicyte

Grant in 2020
Omnicyte is a biotechnology company focused on developing targeted treatments for cancer therapy. It utilizes a proprietary Immuno-Oncology Platform Technology to create recombinant targeted immunomodulators aimed at addressing unmet medical needs in oncology. The company is actively working on treatments for various cancer indications, including ovarian cancer and small cell lung cancer. By advancing its innovative platform, Omnicyte aims to enhance patient outcomes and improve quality of life for individuals affected by these challenging diseases.

Muon Vision

Grant in 2020
Our technology provides a passive, non-invasive X-ray imaging technology that can be used to i) visualize the percolation of process fluids across leaching heaps at scale; ii) monitor the stability of dams, heaps, mining assetts; iii) other industrial and minidng applications where density measurements are of key importance to improve safety and productivity.

SONATA SCIENTIFIC

Grant in 2020
Sonata Scientific is a developer of advanced air purification and antimicrobial products.
Leading Edge Equipment Technologies, Inc. manufactures and supplies manufacturing equipment to solar panel manufacturers. The company offers floating silicon method, which helps to reduce manufacturing cost of silicon wafers, increases commercial solar panel power, and reduces manufacturing emissions. Leading Edge Equipment Technologies, Inc. was formerly known as Leading Edge Crystal Technologies, Inc. and changed its name to Leading Edge Equipment Technologies, Inc. in May 2020. The company was founded in 2008 and is based in Wilmington, Massachusetts.
Paramount Planet Product is an Orono-based startup that aims to cut ocean pollution with low-cost, compostable plant-based drink lid that resembles plastic but will not harm the ocean environment if littered.
Armada Marine Robotics develops asymmetric propulsion technology for enhancing marine maneuverability. The company's headquarters are in Falmouth, Massachusetts.

Full Circle Microbes

Grant in 2020
Full Circle Microbes provides a waste disposal service that converts organic waste into fertilizer. The company was founded in 2019 and is headquartered in Hinesburg, Vermont.

GRO Biosciences

Grant in 2020
GRO Biosciences is leveraging breakthrough technologies from computational protein design and synthetic biology to develop best-in-class protein therapeutics with enhanced properties. The company has established multiple genomically recoded strains of bacteria that can incorporate non-standard amino acids into proteins to confer increased potency, stability, and targeted delivery. GRO Biosciences is applying its technology platform to develop improved protein therapeutics for diabetes, growth disorders and autoimmunity. The company, co-founded by Dr. George Church, is located at the Harvard Life Lab, a shared laboratory space for high-potential life sciences and biotechnology startups founded by Harvard faculty, alumni, students, and postdoctoral scholars.

Solvus Global

Grant in 2020
Developer of a material manufacturing technology designed to specialize in the areas of additive manufacturing, machine learning, and sustainable materials processing. The company's technology provides an online portal for the purchase of quality-controlled, custom-processed, and custom-packaged powders for the cold spray and additive manufacturing that are processed as per quality standards, and customized data management systems are incorporated directly into manufacturing cells, enabling clients to have real-time, secure cloud synchronization and build machine-learning-powered feedback controls to maximize process performance.

ActivSignal

Grant in 2020
ActivSignal is a biotech company that develops protein profiling for diagnostics and other applications. The company was founded in 2016 and is headquartered in Natick, Massachusetts.
Developer of a heat sink optimization platform designed to hybridize computational fluid dynamics. The company develops a compliant vapour chamber technology to eliminate thick thermal interface materials in the form of gap fillers and/or thermal grease in the aforementioned hardware, thereby using analytical, numerical, and experimental methods to consult on complex problems involving momentum, heat and mass transport phenomena.

Travera

Grant in 2020
Travera, LLC operates in the biotechnology industry. The company uses Suspended Microchannel Resonator device to measure change in the weight of a single cancer cell called Mass Accumulation Rate (MAR) biomarker to determine which drugs to prescribe based on the actual responses of their patients’ tumor cells to candidate drugs. The company was founded in 2017 and is headquartered in Cambridge, Massachusetts.

Guardion

Grant in 2020
Guardion is a company focused on developing advanced sensor technology that enhances safety by detecting and tracking potential threats, such as dirty bombs, in urban areas. It has created the world's first radiation detector that utilizes the quantum properties of nanomaterials, allowing for the production of low-cost, sensitive, and low-power detectors that can be deployed on a large scale. The company's innovations include analytical instruments, chemical detectors, and portable radiation detectors, all designed for applications that require high sensitivity, miniaturization, and ease of manufacturing. These technologies support various industries, including aerospace, medical, and national security, by enabling data collection in challenging environments. Guardion has received recognition for its contributions, winning awards such as the MassChallenge 2017 Gold Prize and participating in the Techstars Autonomous Tech Accelerator.

CoreMap

Grant in 2020
CoreMap, Inc. develops a diagnostic technology for electrophysiologists for treating atrial fibrillation. It offers CoreMap micro-electrode solution for mapping tissue properties (ability to map sequentially). The company also provides CoreMap ultra-high resolution electrodes reveal the details of activation despite fibrillation. The company was incorporated in 2016 and is based in Winooski, Vermont.

Lura Health

Grant in 2020
Lura Health is a company that specializes in developing tooth-mounted sensors designed to monitor oral health through saliva analysis. Founded in 2016 and based in Cambridge, Massachusetts, Lura Health's wireless intra-oral sensors allow users to continuously track key diagnostic metrics related to their oral environment. The sensors are designed to sit comfortably on a single tooth and monitor oral acidity, transmitting data to a mobile application. This technology provides users with meaningful insights and instant feedback, empowering them to take control of their health and improve personal health management by setting and achieving health goals.

bosWell

Grant in 2020
bosWell provides a record-keeping platform tailored for community-based organizations, facilitating simple and secure data collection. The platform includes a dashboard and customizable client intake forms that allow organizations to gather client data across various devices. By digitizing data and generating insights, bosWell enables organizations to streamline their operations, save time, and enhance client outcomes. This approach supports community organizations in effectively managing their records and improving service delivery.

UCHU Biosensors

Grant in 2020
UCHU Biosensors develops a platform of tooth mounted sensors to effortlessly track health through saliva.
Foresight Science & Technology, Inc. (Foresight), founded in 1980, is a provider of commercialization, technology transfer, and due diligence services. Their methodology is described in The Art & Science of Technology Transfer, a best-selling textbook by their founder, Dr. Phyllis “Leah” Speser, who also helped develop the legislation that created the US innovation ecosystem and is emulated by innovation ecosystems around the globe. Their customers include: universities, companies, government agencies, laboratories, foundations, inventors and investors. Their services include assessing technologies, marketing and licensing technologies, training and mentoring, launching programs, and providing operational and technical support.
New Equilibrium Biosciences focuses on the research and development of therapeutic drugs aimed at treating cancer, neurodegenerative diseases, and other medical conditions. The company specializes in targeting intrinsically disordered proteins (IDPs), which play a significant role in various disorders. By integrating artificial intelligence with quantum chemistry, New Equilibrium leverages biophysical experiments to explore opportunities for structure-based drug design. This approach includes the creation of compound libraries specifically for IDPs, allowing for the identification of potential drug candidates that can interact with transient binding pockets on these proteins. Through its innovative platform, New Equilibrium aims to enhance drug discovery processes and improve treatment options within the healthcare sector.

RizLab Health

Grant in 2020
Rizlab Health is a medical device startup founded in 2018 and based in East Princeton. The company specializes in providing practitioners and patients with rapid blood count readings, specifically focusing on white blood cell analysis. Rizlab Health's electronic cytometer and analyzer utilize a cartridge system to quantify key cellular components, such as neutrophils and lymphocytes. This technology enables hospitals and healthcare providers to quickly and affordably monitor patients' white blood counts, which is crucial for diagnosing conditions like sepsis and distinguishing between bacterial and viral infections. By offering a fast, portable, and cost-effective health monitoring solution, Rizlab Health aims to enhance patient care and streamline clinical decision-making processes.

Metalmark

Grant in 2020
Metalmark creates nanostructured materials that destroy submicron scale airborne pollutants and toxins to support healthy indoor air quality. It aims to address the challenges associated with air pollution and climate change. The company's air cleaning technology utilizes catalytic materials to filter the air with nanoscale precision. It was founded in 2017 and is headquartered in Boston, Massachusetts.

Aclarity

Grant in 2020
Aclarity, LLC is a manufacturer of innovative water purification devices aimed at improving water treatment processes for residential use. Founded in 2017 and headquartered in the United States, the company leverages patent-pending electrochemical technology to effectively remove a wide range of contaminants, including pathogens, metals, volatile organic compounds (VOCs), per- and polyfluoroalkyl substances (PFAS), and ammonia from water. Aclarity's systems are designed to provide cost-effective, low-maintenance solutions, ensuring comprehensive purification while promoting safe and clean water for its customers and end-users.

Infinite Cooling

Grant in 2020
Infinite Cooling Inc. is a company focused on water recovery systems designed for power plants and other industrial facilities. Founded in 2017 and based in Massachusetts, the company employs innovative technology utilizing high-voltage electric fields to capture and recycle water that evaporates from cooling towers. This process significantly reduces water waste and helps mitigate water scarcity. By implementing its systems, Infinite Cooling enables power plants, data centers, and factories to lower their water consumption and treatment costs, promoting sustainability in industrial operations.

Mizar Imaging

Grant in 2020
Mizar Imaging is a light sheet illumination system that is modular and designed for high-resolution imaging. The company was founded in 2017 and is headquartered in Woods Hole, Massachusetts.

Merrimack College

Grant in 2020
Merrimack College is a selective, independent college in the Catholic, Augustinian tradition whose mission is to enlighten minds, engage hearts and empower lives. Leadership Mission History Accreditations Fast Facts Recognition & Rankings The College offers undergraduate degrees in the liberal arts, business, science and engineering, and education programs; it also offers master’s programs in accounting, computer science, education, engineering, health sciences, and management; and a range of certificate, licensure and degree completion programs. Throughout the curriculum, students can take advantage of hands-on opportunities including cooperative education and internships, research with faculty, study abroad and service learning. And, because our curriculum emphasizes the liberal arts, graduates are prepared to be imaginative, analytical, aware of trends and historical perspectives, clear thinking, and adaptable to changes in their career.

ChameleonCloud

Grant in 2020
Cloud services have become ubiquitous to all major 21st century economic activities. However, cloud services and technologies can be significantly more powerful than they are now. A persistent barrier to further advancement has been the lack of a large-scale and open cloud research platforms. With funding from the National Science Foundation (NSF), the Chameleon project will provide such a large-scale platform to the open research community allowing them explore transformative concepts in deeply programmable cloud services, design, and core technologies. Chameleon will allow users to explore problems ranging from the creation of Software as a Service to kernel support for virtualization. This broad range of supported research includes many other areas such as developing Platforms as a Service, creating new and optimizing existing Infrastructure as a Service components, investigating software-defined networking, and optimizing virtualization technologies. The Chameleon testbed, will be deployed at the University of Chicago and the Texas Advanced Computing Center and will consist of 650 multi-core cloud nodes, 5PB of total disk space, and leverage 100 Gbps connection between the sites. While a large part of the testbed will consist of homogenous hardware to support large-scale experiments, a portion of it will support heterogeneous units allowing experimentation with high-memory, large-disk, low-power, GPU, and co-processor units. The project will also leverage existing FutureGrid hardware at the University of Chicago and the Texas Advanced Computing Center in its first year to provide a transition period for the existing FutureGrid community of experimental users. To support the broad range of experiments experiments described above, the project will support a graduated configuration system allowing full user configurability of the software stack, from provisioning of bare metal and network interconnects to delivery of fully functioning cloud environments. A special feature of Chameleon is that it provides for an exceptionally close integration of clouds and networks, which substantially enhances the capabilities of both. In addition, to facilitate experiments, Chameleon will support a set of services designed to meet researchers needs, including support for experimental management, reproducibility, and repositories of trace and workload data of production cloud workloads. The project is led by the Computation Institute at the University of Chicago and partners from the Texas Advanced Computing Center at the University of Texas at Austin, the International Center for Advanced Internet Research at Northwestern University, the Ohio State University, and University of Texas at San Antonio, comprising a highly qualified and experienced team. The team includes members from the NSF supported FutureGrid project and from the GENI community, both forerunners of the NSFCloud solicitation under which this project is funded. Chameleon will also form a set of partnerships with commercial and academic clouds, such as Rackspace, CERN and Open Science Data Cloud (OSDC), and will partner with other testbeds, notably GENI and INRIA's Grid'5000 testbed.

Veramorph

Grant in 2020
VeraMorph is a pharmaceutical company that is developing an oral dosage technology based on polymers. The company was founded in 2017 and is headquartered in Mansfield, Massachusetts.

Soliyarn

Grant in 2020
Developer of sustainable textile finishing technologies intended to reduce pollution in the textile industry. The company's platform utilizes chemical vapor deposition (CVD) and organic polymers to create functional fabrics with conductivity, water repellency, and dyeing capabilities, all without using water or harmful chemicals, enabling the textile industry to make eco-friendly clothing with improved performance and reduced environmental impact.

The Emerald Tutu

Grant in 2020
The Emerald Tutu develops floating landscape infrastructure to mitigate the effects of climate change. The company provides waterfront amenities.

2Witech Solutions

Grant in 2020
2Witech Solutions specializes in the development of rapid and low-cost PFAS sensors. 2Witech's PFAS rapid sensing film allows for accurate PFAS concentration measurements without the long wait times or high costs associated with traditional PFAS laboratory testing.
Higgins Environmental Associates provides LSP and environmental consulting services, including assessments, senior reviews, remediation design, and oversight. They rapidly assess, mitigate, and reduce health risks posed by toxic cyanobacteria in lakes and ponds.
Coagulo Medical Technologies, Inc. is a Massachusetts-based company focused on developing advanced testing systems for coagulation management. The company provides a portable and connected precision-medicine platform that enables healthcare professionals to detect, identify, and quantify the effects of various anticoagulants in whole blood. By utilizing a combination of patent-pending coagulation assays, microfluidic technology, and data analytics, Coagulo's system offers actionable results, facilitating personalized diagnosis and management of coagulation-related conditions. This innovative approach aims to improve healthcare outcomes by making coagulation testing more accessible and efficient for both providers and patients.

Ichosia Biotechnology

Grant in 2020
Developer of derived red blood cells intended to leverage natural genetic processes to support healthcare providers and patients in need. The company's platform has created red blood cells by genetically engineering human stem cells, enabling patients at risk to receive blood on demand.

Alloy Enterprises

Grant in 2020
Alloy Enterprises Inc., based in Somerville, Massachusetts, specializes in developing 3D printing technologies aimed at addressing inefficiencies in traditional manufacturing processes. Incorporated in 2020, the company focuses on industrial engineering and manufacturing solutions, particularly in the production of aluminum components. Alloy Enterprises has created an innovative aluminum additive technology that allows for the production of dense and cost-effective parts without the use of expensive and hazardous powders. This advancement enables clients to overcome the limitations posed by conventional manufacturing methods, promoting innovation and facilitating progress in lightweight design and emissions reduction.

Biocogniv

Grant in 2020
Biocogniv Inc. specializes in developing artificial intelligence-powered diagnostic tools tailored for hospitals. Founded in 2019 and based in Burlington, Vermont, the company creates plugins for electronic health records (EHRs) that enhance clinical decision-making. Its initial product screens patients for COVID-19 by rapidly analyzing standard blood test results, achieving a sensitivity rate of 95%. Additionally, Biocogniv's technology aims to predict sepsis-related in-hospital mortality and the need for intensive care unit admission during emergency department visits. By seamlessly integrating with EHR workflows, Biocogniv's solutions facilitate accurate and non-invasive diagnostic methods, thereby improving patient outcomes and operational efficiency in the medical sector.

InThePendant

Grant in 2020
InThePendant is a technological platform that aims to provide meaningful insight. The company was founded in 2019 and is headquartered in Lexington, Massachusetts.
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