IndieBio

IndieBio is an accelerator firm established in 2014 and based in San Francisco, California, with an additional office in New York. It specializes in startups that utilize synthetic biology to address significant global challenges. IndieBio runs four-month accelerator programs aimed at both companies and teams with innovative ideas, focusing on seed-stage and early-stage investments. The firm typically invests $250,000, providing $50,000 in exchange for eight percent equity in biotech startups, with the possibility of an additional $25,000 as a convertible loan note. IndieBio prioritizes investments in businesses that leverage biology as the core of their technology, particularly in life sciences, biotechnology, and related fields. The firm favors teams with a minimum of two co-founders and is open to investing in startups from various geographical locations.

Alexander Hall-Daniels

Associate

Parikshit Sharma

Partner

Past deals in Biotechnology

Beeflow

Convertible Note in 2023
Beeflow S.A. is a company that specializes in professional pollination services, focusing on the enhancement of bee health and efficiency. Founded in 2016 and headquartered in Buenos Aires, Argentina, Beeflow employs scientific techniques and organic compounds to improve the immune systems of bees, enabling them to effectively pollinate specific crops. The company has demonstrated significant success in increasing crop yields, with reported improvements ranging from 20% to 90% in various fruits such as blueberries, almonds, raspberries, and kiwifruit. Since its inception, Beeflow has expanded its operations to the United States and continues to grow its presence, particularly in Ventura County, California. The company's efforts aim to address the challenges of declining bee populations while supporting agricultural productivity.

Cayuga Biotech

Seed Round in 2023
Cayuga Biotech is a startup developing novel hemostatic drugs and devices to reduce uncontrollable bleeding which is a leading cause of death from traumatic injuries. The company's polyphosphate-based drug accelerates the body's own clotting process to contain clotting at the injury site and thus minimize the risk of side effects. Cayuga is developing drugs for indications that treat traumatic hemorrhage as well as rare bleeding disorders.

DNALite Therapeutics

Convertible Note in 2023
DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes proprietary technology to deliver therapeutic DNA directly to intestinal stem cells, aiming to address the underlying causes of diseases such as Familial Adenomatous Polyposis (FAP), a hereditary form of colorectal cancer that often necessitates invasive surgical procedures. By targeting these root causes, DNALite seeks to prevent disease progression rather than merely managing symptoms, offering a potentially transformative approach to treating gastrointestinal disorders, including colorectal cancer and Crohn's disease.

Multus

Series A in 2023
Multus Media enables cultivated meat companies to scale affordably and profitably. We take care of the growth media, so our customers can focus on bringing delicious, sustainable meat to the world. Taking a machine learning-based approach we can design a completely animal-free growth media that is tailored for animal cells. This is particularly useful for the cultivated meat industry where there are needs of high performance at large scale. Multus Media was established in 2019 and is headquartered in London, England.

Mirá Biotech

Seed Round in 2022
Mirá Biotech is a biotechnology company focused on the development of sustainable, formaldehyde-free engineered wood products. By utilizing waste materials, such as sugar cane bagasse, the company aims to create all-natural alternatives to traditional wood boards, thereby promoting a circular economy. This innovative approach not only eliminates the need for tree harvesting but also contributes to sustainable industrial practices, positioning Mirá Biotech as a leader in environmentally friendly manufacturing solutions.

Prellis Biologics

Series C in 2022
Prellis Biologics is building human tissues for drug development, and ultimately, developing human organs for transplantation. Bioprinting vascularized human tissue and organs will revolutionize healthcare. Prellis Biologics'​ technology leverages massive gains in print speed and resolution to break the microvasculature barrier.

BioLumen

Convertible Note in 2022
BioLumen is a nutritional technology company that develops a patented dietary fiber technology platform that reduces the negative effect of a diet heavy in processed foods. BioLumen's technology is composed of insoluble dietary fiber matrix covered with a blend of food ingredients created from the latest drug delivery system research. The company's product, a nutraceutical, focuses on high risk individuals with prediabetes to help manage blood sugar levels, protect their liver from excess sugar and feed their gut microbiome, delivering health benefits. BioLumen was founded on 2018 and is headquartered in San Francisco, California.

Oobli

Series B in 2022
Derived from exotic plants, protein sweeteners are rare compounds that provide an amazing taste without the calories.

Voyage Foods

Series A in 2022
Voyage Foods has made sustainable and scalable alternatives to foods that have current obstacles –environmental, social, and health alike. Our breakthrough technology provides endless opportunities to make delicious, nearly identical, versions of beloved foods, without compromising individual health or our planet. We replicated the world’s favorite foods so that we can all enjoy them, forever.

ClimateCrop

Seed Round in 2022
ClimateCrop technologies allow plants to store more carbon and energy, resulting in increased yields in biomass or fruit states. Founded in 2021 and is based in Ness Ziona.

AnimalBiome

Series A in 2022
AnimalBiome focuses on improving the gut health of dogs and cats in the United States that suffer from chronic digestive disorders. The company offers microbiome-based supplements and non-invasive diagnostic tools designed to identify imbalances in the gut microbiome. Utilizing deoxyribonucleic acid sequencing, AnimalBiome's diagnostic services assess the balance of gut bacteria, allowing pet owners to gain insights into their pets' gut health. This information enables tailored supplementation aimed at restoring gut balance, ultimately promoting a healthier and happier life for pets.

UPSIDE Foods

Series C in 2022
UPSIDE Foods, formerly known as Memphis Meats, is a company headquartered in San Francisco, California, that specializes in producing cultured meat directly from animal cells. Founded in 2015 by Uma Valeti and Nicholas Genovese, the company focuses on developing products such as hot dogs, sausages, burgers, and meatballs without the need to raise and slaughter animals. This innovative approach to meat production requires significantly less caloric input, water, land, and energy compared to traditional methods, while also aiming to provide consumers with cleaner meat products that are free from harmful chemicals.

DNALite Therapeutics

Venture Round in 2022
DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes proprietary technology to deliver therapeutic DNA directly to intestinal stem cells, aiming to address the underlying causes of diseases such as Familial Adenomatous Polyposis (FAP), a hereditary form of colorectal cancer that often necessitates invasive surgical procedures. By targeting these root causes, DNALite seeks to prevent disease progression rather than merely managing symptoms, offering a potentially transformative approach to treating gastrointestinal disorders, including colorectal cancer and Crohn's disease.

OzoneBio

Seed Round in 2022
OzoneBio is a cleantech company that focuses on lignocellulosic waste-derived bio-plastics production. In its workflow, they utilize the unique technology of dead cell fermentation («Zombie cells») that allows them to convert challenging/toxic feedstocks into high-value products and avoid significant expenses and complications related to live-cell fermentation. OzoneBio was founded in 2021 and is headquartered in Toronto, Canada.

Innatrix

Seed Round in 2022
Innatrix is an agricultural biotechnology company focused on developing innovative biological and chemical products aimed at controlling challenging crop diseases, pests, and weeds. Utilizing patented protein evolution technology, the company has created a peptide and RNA interference (RNAi) delivery platform that offers eco-friendly alternatives for crop protection. Innatrix's proprietary automated platform allows for advanced protein engineering through continuous laboratory evolution and other methods, such as phage display. This technology enhances researchers' capabilities in control, reporting, recording, simulation, and remote access, positioning Innatrix as a leader in sustainable agricultural solutions.

Innatrix

Convertible Note in 2022
Innatrix is an agricultural biotechnology company focused on developing innovative biological and chemical products aimed at controlling challenging crop diseases, pests, and weeds. Utilizing patented protein evolution technology, the company has created a peptide and RNA interference (RNAi) delivery platform that offers eco-friendly alternatives for crop protection. Innatrix's proprietary automated platform allows for advanced protein engineering through continuous laboratory evolution and other methods, such as phage display. This technology enhances researchers' capabilities in control, reporting, recording, simulation, and remote access, positioning Innatrix as a leader in sustainable agricultural solutions.

LizarBio Therapeutics

Pre Seed Round in 2022
PluriCell wants to positively impact the lives of millions of patients suffering from chronic heart failure condition by injecting healthy bona fide lab-made human heart cells in their failing heart, improve its function and, ultimately, the clinical outcome of the patients. Our tech enables us not only tackle heart diseases, but potentially, many chronic disorders currenly untractable.

Finless Foods

Series B in 2022
Finless Foods Inc. is a biotechnology company based in Emeryville, California, focused on producing sustainable seafood alternatives through cellular agriculture technologies. Founded in 2017, the company specializes in growing marine-animal cells to create seafood products, including bluefin tuna. Finless Foods aims to provide a healthier and environmentally friendly alternative to traditionally caught and farmed seafood, offering consumers a cost-effective option that does not compromise on taste or dietary preferences. The company's mission is to develop and mass manufacture innovative marine animal food products that promote sustainability and accessibility in the seafood market.

QuantumCyte

Convertible Note in 2022
QuantumCyte, Inc. is a biotechnology company based in Sunnyvale, California, founded in 2014. It specializes in developing a cell analysis system designed to enhance drug efficacy predictions and advance cancer research. By analyzing large numbers of cells, QuantumCyte aims to deepen the understanding of immune system and cancer biology. The company utilizes artificial intelligence in its pathology technology platform to provide precise cellular data, facilitating single-cell analysis for healthcare providers. Its team comprises experts from various fields, including biology, high technology, and diagnostics, with backgrounds in esteemed organizations such as Stanford and Genentech. QuantumCyte has established strong collaborations with specialists in cancer and genomic sequencing to meet fundamental research needs and ensure the scalability of its products.

Avisa Myko

Convertible Note in 2022
Avisa Myko Inc. is a biotechnology company based in San Francisco, California, that specializes in the production of natural soluble melanin through precision fermentation technology. This innovative approach allows the company to manufacture melanin at scale and at an affordable cost, ensuring high purity and ease of application across various industries. Avisa Myko's melanin serves multiple purposes, including protection against ionizing radiation and electricity generation, and is utilized in cosmetics, biomedicine, organic semiconductors, biosensors, and textiles. The company is also developing a prototype sunscreen that leverages its melanin as an ultraviolet blocker without relying on conventional chemical or mineral filters. Through its patented technology, Avisa Myko aims to improve human health and environmental sustainability by integrating melanin into products such as latex, fabrics, and laminated materials.

NovoNutrients

Convertible Note in 2022
NovoNutrients is focused on converting industrial waste carbon dioxide emissions into high-value protein ingredients for food and animal feed. The company has developed a fermentation platform that utilizes proprietary microbes and advanced gas fermentation systems to transform CO2, along with hydrogen and oxygen, into complete and safe single-cell protein. This innovative approach not only provides sustainable protein sources to support a growing population but also plays a role in combating climate change through carbon capture and utilization. By addressing both food security and environmental sustainability, NovoNutrients aims to meet the increasing demand for alternative protein solutions.

ArgenTAG

Convertible Note in 2022
ArgenTAG specializes in developing synthetic DNA barcoding technology aimed at enhancing the capabilities of long-read sequencing applications in genomics. By addressing the limitations associated with reduced multiplexing capacity and sequencing throughput, ArgenTAG enables the simultaneous analysis of thousands of samples. The company integrates advanced micro-fabrication techniques with next-generation DNA sequencing and molecular biology, leveraging reengineered error correction technologies initially derived from digital communications. This innovative approach facilitates the decentralization of genome sequencing, allowing medical professionals to effectively analyze antibodies and perform single-cell sequencing, thus advancing the field of personalized medicine.

Nat4Bio

Seed Round in 2022
At NAT4Bio, we develop naturally-sourced coatings that protect produce from spoilage and decay. By leveraging microbial fermentation of selected fungi & bacteria and through carefully designed downstream processes, we obtain cell-free compounds, meaning we use microbes' active principles without the microbes themselves. Our first product is a natural and edible coating for fresh lemons that could potentially replace the combination of waxes and chemical fungicides. We are also prototyping formulations for blueberries and avocados, and we aim to expand our portfolio to address the needs of every fruit class.

Nat4Bio

Convertible Note in 2022
At NAT4Bio, we develop naturally-sourced coatings that protect produce from spoilage and decay. By leveraging microbial fermentation of selected fungi & bacteria and through carefully designed downstream processes, we obtain cell-free compounds, meaning we use microbes' active principles without the microbes themselves. Our first product is a natural and edible coating for fresh lemons that could potentially replace the combination of waxes and chemical fungicides. We are also prototyping formulations for blueberries and avocados, and we aim to expand our portfolio to address the needs of every fruit class.

ArgenTAG

Pre Seed Round in 2022
ArgenTAG specializes in developing synthetic DNA barcoding technology aimed at enhancing the capabilities of long-read sequencing applications in genomics. By addressing the limitations associated with reduced multiplexing capacity and sequencing throughput, ArgenTAG enables the simultaneous analysis of thousands of samples. The company integrates advanced micro-fabrication techniques with next-generation DNA sequencing and molecular biology, leveraging reengineered error correction technologies initially derived from digital communications. This innovative approach facilitates the decentralization of genome sequencing, allowing medical professionals to effectively analyze antibodies and perform single-cell sequencing, thus advancing the field of personalized medicine.

Sóliome

Seed Round in 2022
Sóliome is a biotechnology company founded in 2021 and based in San Francisco, California. The company specializes in developing protein-based sunscreens designed to be safe for both the skin and the environment. These innovative products aim to reduce inflammation and skin damage caused by traditional sunscreens, which often contain harmful xenobiotic ingredients that can absorb into the skin and contribute to ecological harm. Sóliome's approach allows customers to protect their skin from harmful rays without the adverse effects associated with conventional sunscreen formulations.

Sóliome

Convertible Note in 2022
Sóliome is a biotechnology company founded in 2021 and based in San Francisco, California. The company specializes in developing protein-based sunscreens designed to be safe for both the skin and the environment. These innovative products aim to reduce inflammation and skin damage caused by traditional sunscreens, which often contain harmful xenobiotic ingredients that can absorb into the skin and contribute to ecological harm. Sóliome's approach allows customers to protect their skin from harmful rays without the adverse effects associated with conventional sunscreen formulations.

Cayuga Biotech

Seed Round in 2022
Cayuga Biotech is a startup developing novel hemostatic drugs and devices to reduce uncontrollable bleeding which is a leading cause of death from traumatic injuries. The company's polyphosphate-based drug accelerates the body's own clotting process to contain clotting at the injury site and thus minimize the risk of side effects. Cayuga is developing drugs for indications that treat traumatic hemorrhage as well as rare bleeding disorders.

Ceragen

Convertible Note in 2022
Ceragen is a biotechnology company based in Kitchener, Ontario, focused on enhancing agricultural productivity through plant microbiome engineering. The company specializes in precision microbiome engineering, offering inoculant products specifically designed for controlled environment agriculture. These products aim to provide farmers with natural solutions that enhance crop yields, allowing them to grow more food in smaller spaces. By improving plants' resilience to environmental stressors, Ceragen's innovations support sustainable farming practices and contribute to the efficient use of land resources, addressing the growing need to feed the global population.

Capra Biosciences

Convertible Note in 2022
Capra Biosciences is a biotechnology company harnessing biology for efficient and low-carbon production of everyday chemicals. It develops bioreactor technology designed to make the production of chemical products more efficient. The company developed a biofilm bioreactor which has the potential to significantly reduce the downstream processing requirements and costs inherent in the bio-manufacturing of products such as fuels. Capra Biosciences was founded in 2020 and is headquartered in Alexandria, VA.

Tômtex

Pre Seed Round in 2022
Tômtex is a developer of sustainable, bio-based materials that aim to reduce environmental impacts by utilizing food waste. The company specializes in creating alternatives to faux and animal leather, using natural biodegradable sources such as shellfish waste, mushrooms, and coffee grounds. By providing these innovative materials, Tômtex enables businesses to lower their greenhouse gas emissions and minimize their carbon footprint, contributing to a more sustainable future. The focus on 100% naturally bio-based products aligns with the growing demand for eco-friendly solutions in various industries.

ClimateCrop

Convertible Note in 2021
ClimateCrop technologies allow plants to store more carbon and energy, resulting in increased yields in biomass or fruit states. Founded in 2021 and is based in Ness Ziona.

Veloz Bio

Seed Round in 2021
Veloz Bio is a biotechnology company established in 2021 and located in Monterrey, Nuevo León. The company specializes in molecular farming to develop and manufacture sustainable and affordable animal-free and alternative proteins. By leveraging efficient plant metabolism, Veloz Bio has created a rapid protein production system that enables scalable growth of new proteins. This innovation allows biotech firms to gain expertise in essential areas of protein production, including supercritical fluid extraction and membrane purification. Through its focus on alternative proteins, Veloz Bio aims to contribute to a more sustainable food supply.

Veloz Bio

Convertible Note in 2021
Veloz Bio is a biotechnology company established in 2021 and located in Monterrey, Nuevo León. The company specializes in molecular farming to develop and manufacture sustainable and affordable animal-free and alternative proteins. By leveraging efficient plant metabolism, Veloz Bio has created a rapid protein production system that enables scalable growth of new proteins. This innovation allows biotech firms to gain expertise in essential areas of protein production, including supercritical fluid extraction and membrane purification. Through its focus on alternative proteins, Veloz Bio aims to contribute to a more sustainable food supply.

Unlocked Labs

Seed Round in 2021
Solving gout using engineered probiotics

ClimateCrop

Seed Round in 2021
ClimateCrop technologies allow plants to store more carbon and energy, resulting in increased yields in biomass or fruit states. Founded in 2021 and is based in Ness Ziona.

Unlocked Labs

Convertible Note in 2021
Solving gout using engineered probiotics

Zymochem

Seed Round in 2021
ZymoChem, Inc. develops microbes and bioprocesses that enable production of chemicals from renewable sources, such as sugars. The company was founded in 2013 and is based in Emeryville, California.

Gatehouse Bio

Seed Round in 2021
Gatehouse Bio is a biotechnology company based in Waltham, Massachusetts, focused on advancing precision medicine through the development of targeted therapeutics. Founded in 2016, the company utilizes a novel bioinformatics platform to identify small ribonucleic acid (sRNA) biomarkers, which are essential for uncovering disease signatures and facilitating drug discovery and repurposing. Their technology employs machine learning to achieve high accuracy in classifying patient samples, making it a valuable tool for identifying custom biomarker panels tailored to individual needs. Gatehouse Bio collaborates with leading drug developers to discover novel drug targets and develop companion diagnostics, with applications validated in areas such as cardiology, neurology, oncology, respiratory diseases, and rare diseases.

Tidal Vision

Venture Round in 2021
Tidal Vision Inc. is a company based in Ferndale, Washington, that focuses on manufacturing sustainable products derived from ocean waste, such as salmon skin and discarded crab shells. Founded in 2015, Tidal Vision offers a range of innovative products, including Alaska Salmon leather items like wallets, belts, shoes, and boots. Additionally, the company produces a variety of chitin and chitosan-based products, which serve multiple purposes, such as a fining agent for clarifying beverages, water treatment solutions, and antimicrobial applications. Other offerings include Crystal Clarity, a water clarifier for pools and spas, Game Meat Protector to prevent spoilage, High Tide, a natural shellfish extract, Tidal Grow, an all-purpose plant food, and Tidal Scrub, a sponge designed to eliminate germs and odors. Through its commitment to sustainability, Tidal Vision is positioned at the intersection of biotechnology and manufacturing.

Pyrone Systems

Seed Round in 2021
Pyrone Systems develops biopesticides that combine biology with chemistry. The company was founded in 2021.

Grand Bio

Seed Round in 2021
Grand Bio is working to improve the efficiency with which cells create their own growth factors. The firm provides supplements that boost growth factors in the medium in which cells live and thrive.

Pyrone Systems

Convertible Note in 2021
Pyrone Systems develops biopesticides that combine biology with chemistry. The company was founded in 2021.

Grand Bio

Convertible Note in 2021
Grand Bio is working to improve the efficiency with which cells create their own growth factors. The firm provides supplements that boost growth factors in the medium in which cells live and thrive.

New Culture

Series A in 2021
New Culture Inc. is a food and beverage company that specializes in producing cheese from protein using innovative methods. By employing microflora to create dairy proteins and dairy products, the company aims to revolutionize traditional cheese-making processes. Founded in 2018 and headquartered in San Francisco, California, New Culture is committed to developing sustainable and alternative cheese options that appeal to a growing market of health-conscious and environmentally aware consumers.

Prothegen

Seed Round in 2021
Prothegen is a biotechnology company that develops cutting-edge medicines for precisely regulating cell death. The company is based in Palo Alto, California.

Prothegen

Convertible Note in 2021
Prothegen is a biotechnology company that develops cutting-edge medicines for precisely regulating cell death. The company is based in Palo Alto, California.

OncoPrecision

Seed Round in 2021
We're developing personalized assays to determine the most suitable medication for cancer therapy at the patient level. Through our proprietary Drug Activity Ranking, oncologists will be able to make data-driven decisions regarding cancer therapy selection based on patient-derived samples. Our goal is to democratize access to precision oncology to improve patients' lives.

microTERRA

Seed Round in 2021
microTERRA creates sustainable protein for farmers in LATAM. Protein is the largest cost to farmers, representing 70% of their total spend. By combining hardware and biotech, microTERRA develops microalgae systems that transform wastewater into a sustainable protein and clean water. Our first customers are fish farms. We transform their wastewater into fish feed, onsite, lowering their production costs, producing protein sustainably and cleaning the water.

California Cultured

Seed Round in 2021
California Cultured is a food company based in Davis, California, that specializes in producing sustainable, lab-grown cocoa through advanced cellular agriculture techniques. Founded in 2020, the company aims to create cocoa that is less bitter and requires less sugar, enhancing the taste while promoting health benefits. By stimulating cocoa cells with common food ingredients, California Cultured ensures the growth of premium-quality cocoa without the ethical and environmental issues associated with traditional cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious cocoa products that are both sustainable and socially responsible.

Kyomei

Seed Round in 2021
Kyomei is a company based in Oxford, England, that focuses on developing a plant-based production system aimed at creating animal proteins for the alternative meat industry. Founded in 2021, Kyomei utilizes plant cell biology to enhance the flavor of meat alternatives by scaling the production of myoglobin in plants, which contributes to the umami taste. This innovative approach not only aims to improve the sensory experience of plant-based meats but also seeks to reduce the environmental impact associated with traditional animal farming. By providing consumers with flavorful plant-based meat options, Kyomei positions itself as a key player in the growing alternative meat market.

PunaBio

Pre Seed Round in 2021
PunaBio is a Buenos Aires-based company that develops biological products aimed at enhancing agricultural productivity through environmentally friendly methods. By utilizing extremophile microorganisms, PunaBio focuses on improving crop nutrition, which contributes to increased yields and better crop quality. Their products are designed to enable farmers to cultivate crops on degraded soils and restore and enrich agricultural land sustainably. This approach not only helps improve farmers' productivity but also promotes sustainable agricultural practices.

New Age Meats

Series A in 2021
New Age Meats is a biotechnology company based in San Francisco, California, founded in 2017. The company specializes in producing cultivated meat using an automated, data-driven platform and advanced stem cell technology. By growing meat from animal cells rather than relying on traditional animal slaughter, New Age Meats aims to create healthier and more sustainable meat alternatives.

Indee Labs

Convertible Note in 2021
Indee Labs is developing hardware for gene delivery. Our hardware is uniquely positioned for the efficient development and scalable manufacture of gene-modified cell therapies such as chimeric antigen receptor T cells. The technology is being developed with the help of the Australian National Fabrication Facility. We are alumni of NSW Health, IndieBio, Y Combinator and MBC Biolabs (née QB3@953). We are opening up an office in Sydney and have lab space at Bonneville Labs in Berkeley.

Plantruption

Seed Round in 2021
Plantruption builds a brand of sustainability to develop products using seaweed and microalgae. The company is on a mission to create the first plant-based seafood. It researches and collaborates with universities and food technologists to provides Plant-based seafood that’s close in taste and texture to the real deal. Plant-based seafood provides a host of environmental benefits, including alleviating pressures on rapidly depleting fisheries, providing relief to fragile ocean ecosystems, reducing the impact of fishing nets on the ocean plastic problem, and reducing production emissions. The company was founded in 2019 in Dublin, Dublin.

HelEx

Seed Round in 2021
Helex uses its own genomics data, bioinformatics, and intelligent data-driven platform to create, verify, and distribute therapy-specific gRNAs. Founded in 2021 and is based in New York.

HelEx

Convertible Note in 2021
Helex uses its own genomics data, bioinformatics, and intelligent data-driven platform to create, verify, and distribute therapy-specific gRNAs. Founded in 2021 and is based in New York.

Kutanios

Seed Round in 2021
Kutanios is a biotechnology firm focused on creating new compounds for anti-aging, sun care, anti-acne, and skin cleaning items. Headwuartered in London.

Finless Foods

Convertible Note in 2021
Finless Foods Inc. is a biotechnology company based in Emeryville, California, focused on producing sustainable seafood alternatives through cellular agriculture technologies. Founded in 2017, the company specializes in growing marine-animal cells to create seafood products, including bluefin tuna. Finless Foods aims to provide a healthier and environmentally friendly alternative to traditionally caught and farmed seafood, offering consumers a cost-effective option that does not compromise on taste or dietary preferences. The company's mission is to develop and mass manufacture innovative marine animal food products that promote sustainability and accessibility in the seafood market.

Filtricine

Seed Round in 2021
Filtricine, Inc. is a clinical-stage biotechnology company based in Santa Clara, California, focused on developing therapeutic products for cancer treatment. Founded in 2017, the company specializes in a novel nutrient modulation platform that targets and depletes essential nutrients critical for cancer cell growth. By exploiting the metabolic vulnerabilities of cancer cells, Filtricine aims to halt the spread of cancer without relying on traditional drug substances. This approach allows healthcare professionals to utilize targeted nutrient deprivation therapy to address a broad spectrum of cancers effectively.

Beeflow

Series A in 2021
Beeflow S.A. is a company that specializes in professional pollination services, focusing on the enhancement of bee health and efficiency. Founded in 2016 and headquartered in Buenos Aires, Argentina, Beeflow employs scientific techniques and organic compounds to improve the immune systems of bees, enabling them to effectively pollinate specific crops. The company has demonstrated significant success in increasing crop yields, with reported improvements ranging from 20% to 90% in various fruits such as blueberries, almonds, raspberries, and kiwifruit. Since its inception, Beeflow has expanded its operations to the United States and continues to grow its presence, particularly in Ventura County, California. The company's efforts aim to address the challenges of declining bee populations while supporting agricultural productivity.

Diadem Biotherapeutics

Convertible Note in 2021
Diadem Biotherapeutics is a biotechnology company that focuses on creating bio-therapeutical materials produced using organic means. Diadem develops exosomes to treat chronic inflammatory and auto-immune conditions.

QuantumCyte

Convertible Note in 2021
QuantumCyte, Inc. is a biotechnology company based in Sunnyvale, California, founded in 2014. It specializes in developing a cell analysis system designed to enhance drug efficacy predictions and advance cancer research. By analyzing large numbers of cells, QuantumCyte aims to deepen the understanding of immune system and cancer biology. The company utilizes artificial intelligence in its pathology technology platform to provide precise cellular data, facilitating single-cell analysis for healthcare providers. Its team comprises experts from various fields, including biology, high technology, and diagnostics, with backgrounds in esteemed organizations such as Stanford and Genentech. QuantumCyte has established strong collaborations with specialists in cancer and genomic sequencing to meet fundamental research needs and ensure the scalability of its products.

Plantruption

Convertible Note in 2021
Plantruption builds a brand of sustainability to develop products using seaweed and microalgae. The company is on a mission to create the first plant-based seafood. It researches and collaborates with universities and food technologists to provides Plant-based seafood that’s close in taste and texture to the real deal. Plant-based seafood provides a host of environmental benefits, including alleviating pressures on rapidly depleting fisheries, providing relief to fragile ocean ecosystems, reducing the impact of fishing nets on the ocean plastic problem, and reducing production emissions. The company was founded in 2019 in Dublin, Dublin.

Ceragen

Seed Round in 2021
Ceragen is a biotechnology company based in Kitchener, Ontario, focused on enhancing agricultural productivity through plant microbiome engineering. The company specializes in precision microbiome engineering, offering inoculant products specifically designed for controlled environment agriculture. These products aim to provide farmers with natural solutions that enhance crop yields, allowing them to grow more food in smaller spaces. By improving plants' resilience to environmental stressors, Ceragen's innovations support sustainable farming practices and contribute to the efficient use of land resources, addressing the growing need to feed the global population.

Ceragen

Convertible Note in 2021
Ceragen is a biotechnology company based in Kitchener, Ontario, focused on enhancing agricultural productivity through plant microbiome engineering. The company specializes in precision microbiome engineering, offering inoculant products specifically designed for controlled environment agriculture. These products aim to provide farmers with natural solutions that enhance crop yields, allowing them to grow more food in smaller spaces. By improving plants' resilience to environmental stressors, Ceragen's innovations support sustainable farming practices and contribute to the efficient use of land resources, addressing the growing need to feed the global population.

Intrinsic Medicine

Convertible Note in 2021
Inflammatory disease affects us all. We looked 300 million years into our past to imagine a healthier future, beyond the limitations of today’s anti-inflammatory drugs. Lupa Bio is developing an entirely new class of safer, anti-inflammatory therapeutics based on compounds found in mothers’ milk ...because no technology today can screen like the forces of nature. ​

Jointechlabs

Pre Seed Round in 2021
JointechLabs, Inc. is a company focused on enhancing access to cell-based therapies for healthcare providers and patients. Based in Mount Prospect, Illinois, the company has developed the Mini-Stem System, a closed disposable kit designed for the processing and extraction of stromal vascular cell fractions from human tissue. This innovative medical device allows for the efficient preparation of high-quality injectable fat grafts and fat-derived stem cells, facilitating on-site access to optimized adipose-derived stromal cells (ADSC). By streamlining the process of individualized cell and tissue-based therapies, JointechLabs aims to make these advanced treatments more accessible and cost-effective for use in hospitals, clinics, and local medical offices. Since its incorporation in 2012, the company has been dedicated to improving the efficacy and availability of cell therapies in clinical settings.

Stämm

Convertible Note in 2021
Stämm Biotech, founded in 2014 and based in San Francisco, California, specializes in innovative biomanufacturing solutions for the life sciences sector. The company has developed a novel bioproduction system that integrates microfluidics, electroporation, and robotics to address the challenges of scaling in the biotech industry. Stämm's flagship product, the Bioprocessor, is an all-in-one, plug-and-play desktop unit that significantly enhances productivity, being at least 70 times more efficient than conventional bioreactors. Additionally, Stämm offers a suite of products including an automated continuous batch system for microbial growth, tools for tracking biological variations, and systems for monitoring microorganisms to convert data into actionable insights. This technological advancement positions Stämm to unlock a substantial market opportunity in biomanufacturing over the next decade.

Earnest

Pre Seed Round in 2021
At Earnest Earth, we partner with farmers to turn their agricultural waste into proprietary engineered fertilizer that increases crop yields. By managing waste, we save farmers time, space, and help them generate additional income while making a greener and cleaner world. Our patent-pending bioreactors (agricultural waste converters) use composting (heat: kill pathogens), vermicomposting (earthworms: remove heavy metals, infuse microbes), microbes (microorganisms), and machine learning to engineer biofertilizers that increase crop yields (promoting drought resistance, pathogen suppression, and improving soil quality).

Multus

Convertible Note in 2021
Multus Media enables cultivated meat companies to scale affordably and profitably. We take care of the growth media, so our customers can focus on bringing delicious, sustainable meat to the world. Taking a machine learning-based approach we can design a completely animal-free growth media that is tailored for animal cells. This is particularly useful for the cultivated meat industry where there are needs of high performance at large scale. Multus Media was established in 2019 and is headquartered in London, England.

DNALite Therapeutics

Convertible Note in 2021
DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, the company utilizes proprietary technology to deliver therapeutic DNA directly to intestinal stem cells, aiming to address the underlying causes of diseases such as Familial Adenomatous Polyposis (FAP), a hereditary form of colorectal cancer that often necessitates invasive surgical procedures. By targeting these root causes, DNALite seeks to prevent disease progression rather than merely managing symptoms, offering a potentially transformative approach to treating gastrointestinal disorders, including colorectal cancer and Crohn's disease.

OzoneBio

Seed Round in 2021
OzoneBio is a cleantech company that focuses on lignocellulosic waste-derived bio-plastics production. In its workflow, they utilize the unique technology of dead cell fermentation («Zombie cells») that allows them to convert challenging/toxic feedstocks into high-value products and avoid significant expenses and complications related to live-cell fermentation. OzoneBio was founded in 2021 and is headquartered in Toronto, Canada.

Vertical Oceans

Seed Round in 2021
Akualogix is an agrifood tech start-up that produces shrimp, whitefish, and seaweeds in high-tech five-story farming systems. The company uses advanced technologies and sustainable practices in urban, vertical aquafarms to produce fresh shrimp, fish, and umibudo. Its vertical oceans combine multi-trophic biology with advanced digital technologies in modular growing habitats efficiently stacked in a vertical tower. Akualogix was established in 2020 and is based in Singapore.

OzoneBio

Convertible Note in 2021
OzoneBio is a cleantech company that focuses on lignocellulosic waste-derived bio-plastics production. In its workflow, they utilize the unique technology of dead cell fermentation («Zombie cells») that allows them to convert challenging/toxic feedstocks into high-value products and avoid significant expenses and complications related to live-cell fermentation. OzoneBio was founded in 2021 and is headquartered in Toronto, Canada.

Prolific Machines

Seed Round in 2021
Gaia Laboratories revolutionizes cell production, creating powerful solutions for the defining challenges of time. The founding principles behind Gaia Laboratories are to combat climate change, enable space-food, and make cell therapy accessible to everyone.

Avalo

Seed Round in 2021
Avalo is a biotechnology company focused on enhancing crop resilience through innovative gene discovery and control techniques. By employing interpretable machine learning, Avalo accelerates the identification of genes in plants, thereby facilitating the development of improved agricultural crops. The company's artificial intelligence-based platform is designed to uncover the biological origins of traits essential for future agriculture, such as drought tolerance, water-use efficiency, and nutrient density. This advancement in gene discovery not only aids researchers in validating and predicting crop quality but also addresses the challenges posed by a changing climate, contributing to a healthier and more sustainable agricultural landscape.

Wayfinder Biosciences

Seed Round in 2021
Wayfinder Biosciences develops biosensors for ultra-high-throughput screening for high-value molecules. The company's PerfectPath biosensors make invisible molecules visible. These biosensors generate fluorescence based on the concentration of the desired small-molecule — allowing quantification of product titer at high-throughput using fast fluorescence measurements. Wayfinder Biosciences was established in 2021 and is headquartered in San Francisco, CA.

Wayfinder Biosciences

Convertible Note in 2021
Wayfinder Biosciences develops biosensors for ultra-high-throughput screening for high-value molecules. The company's PerfectPath biosensors make invisible molecules visible. These biosensors generate fluorescence based on the concentration of the desired small-molecule — allowing quantification of product titer at high-throughput using fast fluorescence measurements. Wayfinder Biosciences was established in 2021 and is headquartered in San Francisco, CA.

Avalo

Convertible Note in 2021
Avalo is a biotechnology company focused on enhancing crop resilience through innovative gene discovery and control techniques. By employing interpretable machine learning, Avalo accelerates the identification of genes in plants, thereby facilitating the development of improved agricultural crops. The company's artificial intelligence-based platform is designed to uncover the biological origins of traits essential for future agriculture, such as drought tolerance, water-use efficiency, and nutrient density. This advancement in gene discovery not only aids researchers in validating and predicting crop quality but also addresses the challenges posed by a changing climate, contributing to a healthier and more sustainable agricultural landscape.

Beemmunity

Pre Seed Round in 2021
Pesticide protection for bees.

Beemmunity

Convertible Note in 2021
Pesticide protection for bees.

Diptera

Seed Round in 2021
Developing technology to fight mosquitoes with mosquitoes.

Proteinea

Seed Round in 2021
Proteinea is a biotechnology company that focuses on insect-based solutions, specifically utilizing the Black Soldier Fly as a mini-biofactory. By integrating biological science with engineering and molecular techniques, the company aims to reduce the capital and operational costs typically associated with conventional bioreactors. Additionally, Proteinea has developed a protein engineering platform that leverages proprietary artificial intelligence models and computational tools to design next-generation antibodies. This platform enhances the efficacy, safety, and convenience of biologics for antibody medicines, allowing clients to access advanced biologic designs tailored for therapeutic applications. Through these innovative approaches, Proteinea seeks to advance the fields of biotechnology and protein engineering.

Proteinea

Convertible Note in 2021
Proteinea is a biotechnology company that focuses on insect-based solutions, specifically utilizing the Black Soldier Fly as a mini-biofactory. By integrating biological science with engineering and molecular techniques, the company aims to reduce the capital and operational costs typically associated with conventional bioreactors. Additionally, Proteinea has developed a protein engineering platform that leverages proprietary artificial intelligence models and computational tools to design next-generation antibodies. This platform enhances the efficacy, safety, and convenience of biologics for antibody medicines, allowing clients to access advanced biologic designs tailored for therapeutic applications. Through these innovative approaches, Proteinea seeks to advance the fields of biotechnology and protein engineering.

Huue

Convertible Note in 2021
Huue, formerly known as Tinctorium Inc., is a biotechnology company based in Berkeley, California, specializing in sustainable indigo dyeing solutions for the textile and fashion industry. Founded in 2018, the company utilizes a unique technology that mimics natural plant processes within microbes to produce indigo dye. This innovative approach significantly reduces chemical usage in the denim supply chain, offering an environmentally friendly alternative for denim production. By harnessing the power of biotechnology, Huue aims to provide the fashion industry with sustainable coloring options that rely on renewable resources, contributing to a more eco-conscious approach in textile manufacturing.

Huue

Convertible Note in 2021
Huue, formerly known as Tinctorium Inc., is a biotechnology company based in Berkeley, California, specializing in sustainable indigo dyeing solutions for the textile and fashion industry. Founded in 2018, the company utilizes a unique technology that mimics natural plant processes within microbes to produce indigo dye. This innovative approach significantly reduces chemical usage in the denim supply chain, offering an environmentally friendly alternative for denim production. By harnessing the power of biotechnology, Huue aims to provide the fashion industry with sustainable coloring options that rely on renewable resources, contributing to a more eco-conscious approach in textile manufacturing.

OncoPrecision

Pre Seed Round in 2021
We're developing personalized assays to determine the most suitable medication for cancer therapy at the patient level. Through our proprietary Drug Activity Ranking, oncologists will be able to make data-driven decisions regarding cancer therapy selection based on patient-derived samples. Our goal is to democratize access to precision oncology to improve patients' lives.

Lux Bio

Convertible Note in 2021
Lux Bio operates a bioluminescent light platform that harnesses the natural light produced by living organisms through biochemical reactions. The company focuses on developing innovative, eco-friendly lighting solutions that utilize engineered proteins derived from plants and animals, enhancing their performance for commercial use. By leveraging clean technology, Lux Bio aims to offer sustainable lighting options while preventing toxic chemical waste from contaminating oceans. Their flagship product, the Nyoka Light Wand, exemplifies this mission by providing a non-toxic alternative to traditional glow sticks, showcasing the potential of bioluminescence in everyday applications.

OncoPrecision

Convertible Note in 2021
We're developing personalized assays to determine the most suitable medication for cancer therapy at the patient level. Through our proprietary Drug Activity Ranking, oncologists will be able to make data-driven decisions regarding cancer therapy selection based on patient-derived samples. Our goal is to democratize access to precision oncology to improve patients' lives.

Basin Genomics

Convertible Note in 2021
Gypsy Bay Genomics is combining scientific backgrounds in genomics and oncology with startup expertise to translate genetic discoveries into advances in personalized clinical care as it strives to develop technology that will decrease the rates of cervical cancer globally.

Basin Genomics

Seed Round in 2021
Gypsy Bay Genomics is combining scientific backgrounds in genomics and oncology with startup expertise to translate genetic discoveries into advances in personalized clinical care as it strives to develop technology that will decrease the rates of cervical cancer globally.

Lux Bio

Seed Round in 2021
Lux Bio operates a bioluminescent light platform that harnesses the natural light produced by living organisms through biochemical reactions. The company focuses on developing innovative, eco-friendly lighting solutions that utilize engineered proteins derived from plants and animals, enhancing their performance for commercial use. By leveraging clean technology, Lux Bio aims to offer sustainable lighting options while preventing toxic chemical waste from contaminating oceans. Their flagship product, the Nyoka Light Wand, exemplifies this mission by providing a non-toxic alternative to traditional glow sticks, showcasing the potential of bioluminescence in everyday applications.

Aja Labs

Seed Round in 2021
Aja Labs is a biotechnology company that produces biodegradable fiber intended to eliminate the usage of plastic-based fiber. They create solutions for the many dynamic and diverse communities with which they identify. The company uses plants to grow fiber that looks and feels like human hair, enabling people in eliminating the need for chemical-heavy synthetics or human hair in the production of hair extensions. Aja Labs was founded in 2019 and is headquartered in San Francisco, CA.

Aja Labs

Convertible Note in 2021
Aja Labs is a biotechnology company that produces biodegradable fiber intended to eliminate the usage of plastic-based fiber. They create solutions for the many dynamic and diverse communities with which they identify. The company uses plants to grow fiber that looks and feels like human hair, enabling people in eliminating the need for chemical-heavy synthetics or human hair in the production of hair extensions. Aja Labs was founded in 2019 and is headquartered in San Francisco, CA.

NovoNutrients

Seed Round in 2021
NovoNutrients is focused on converting industrial waste carbon dioxide emissions into high-value protein ingredients for food and animal feed. The company has developed a fermentation platform that utilizes proprietary microbes and advanced gas fermentation systems to transform CO2, along with hydrogen and oxygen, into complete and safe single-cell protein. This innovative approach not only provides sustainable protein sources to support a growing population but also plays a role in combating climate change through carbon capture and utilization. By addressing both food security and environmental sustainability, NovoNutrients aims to meet the increasing demand for alternative protein solutions.

Dalton Bioanalytics

Convertible Note in 2021
Dalton Bioanalytics specializes in developing advanced analytical technology aimed at transforming blood analysis into a more efficient and cost-effective process. By digitizing the biochemical composition of blood, the company provides a comprehensive array of actionable health insights, addressing the limitations of traditional laboratory testing. This technology enables the monitoring of various plasma analytes, including proteins, lipids, electrolytes, and small molecules, through a single assay. Dalton Bioanalytics supports the scientific research community in exploring multi-omic biology, thereby facilitating the discovery, development, and delivery of precision medicine. Founded in 2019, the company is headquartered in Los Angeles, California.

Innate Biology

Seed Round in 2021
Panacea Longevity is a biotechnology company aiming to replicate the health benefits of fasting. The company patent-pending fasting mimetic forumuation uses a rigorously selected combination of the same bioactive human metabolites that induce this regenerative "bio-program" to replicate the body’s natural response to fasting without having to fast, enabling customers to have anti-inflammatory and antioxidant effects in human cells that could combat age-associated chronic inflammation and cellular damage. Panacea Longevity was established in 2020 and is based in San Francisco, CA.

Mimio Health

Convertible Note in 2021
Mimio Health is a nutraceutical company focusing on the research and production of mimetic supplements. Its patent-pending fasting mimetic formulation uses a rigorously selected combination of the same bioactive human metabolites that induce this regenerative "bio-program" to replicate the body’s natural response to fasting without having to fast.
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