Digitalis Ventures

Galatea Bio is a biotechnology company based in the United States, founded by Carlos Bustamante, Nicholas Katsanis, and Alexander Ioannidis. The company focuses on improving diagnostic testing and accelerating drug discovery, particularly in underserved populations that have been historically underrepresented in genetics research. Galatea Bio operates a biobank that serves as a biosample-to-bioinformatics platform, utilizing advanced algorithms and innovative analyses to enhance genomic discovery. By identifying patients at risk for severe multi-inflammatory syndromes and infections, Galatea Bio aims to develop new tests, treatments, and cures that can significantly improve healthcare outcomes for diverse populations.

Nuvig Therapeutics is advancing innovative and transformational therapies that are designed to induce natural mechanisms to restore immune homeostasis, rebalance immune function following inflammation, and improve the treatment options for patients. Nuvig is building a pipeline of novel immune therapeutics for chronic inflammatory and autoimmune diseases.

Alpha9 Theranostics is a biopharma company that focuses on radiotherapeutics for the treatment of solid and hematologic malignancies. The company is creating a strong pipeline of radiopharmaceuticals to target solid and hematologic malignancies. Its systematic approach to radiotherapeutic design is fueled by a toolbox of technologies and chemistries, which offers broad potential for expansion into a multitude of oncology targets. Alpha9 Theranostics was founded in 2019 and is headquartered in Vancouver, Canada.

Terray Therapeutics is a biotechnology company based in Pasadena, California, founded in 2018. The company specializes in developing innovative treatments for complex human diseases by integrating experimentation and computation to enhance small molecule drug discovery. Terray's unique platform employs ultra-dense microarray technology alongside artificial intelligence and synthetic chemistry to generate extensive and precise chemical datasets. This allows for a rapid design-make-test-analyze cycle, facilitating efficient exploration of chemical space and mapping biochemical interactions between small molecules and disease causes. By utilizing automation and machine learning, Terray addresses significant therapeutic challenges, ultimately guiding the next cycles of drug design and experimentation.

Judo Bio is a biotechnology company focused on developing precision therapeutics that target specific cell populations to treat genetic diseases. Utilizing an innovative receptor targeting approach, Judo Bio is building a pipeline of therapies designed to benefit patients suffering from both common and rare conditions. Currently, the company is operating in stealth mode, indicating a focus on research and development without public visibility.

GRO Biosciences is focused on developing advanced protein therapeutics by utilizing innovative technologies in computational protein design and synthetic biology. The company has created several genomically recoded strains of bacteria that enable the incorporation of non-standard amino acids into proteins. This approach enhances the potency, stability, and targeted delivery of these therapeutics. GRO Biosciences aims to apply its technology to improve treatments for a range of conditions, including diabetes, growth disorders, and autoimmunity, thereby addressing significant unmet medical needs.

Expressable is an online speech therapy practice that focuses on enhancing communication for individuals with speech and language disorders, particularly children. By employing a parent-focused care model, Expressable integrates speech therapy techniques into the daily lives of users, thereby improving outcomes and experiences. The platform offers a range of services, including therapy for accent modification, aphasia, apraxia of speech, autism spectrum disorder, and various language disorders. It facilitates consistent practice through weekly activities, enabling users to develop their communication skills effectively.

Elegen is a biotechnology company founded in 2017, focused on developing microfluidic technology to advance synthetic biology. Led by Dr. Matthew Hill, Elegen aims to revolutionize the field by engineering entire genomes and creating innovative DNA synthesizers. Their technology is designed to enhance the speed and efficiency of DNA sequence testing, thereby facilitating significant progress in biomedical research and healthcare applications. Through these efforts, Elegen seeks to contribute to the rapid development of solutions that address various challenges in the life sciences sector.

Alterome Therapeutics is a biotechnology company focused on precision oncology, dedicated to developing targeted therapeutics that specifically address validated oncogenic drivers in cancer. The firm aims to discover and create alteration-specific therapies that provide hope and improved treatment options for individuals affected by cancer. By concentrating on high-value oncogenic alterations, Alterome Therapeutics seeks to enhance the effectiveness of cancer treatments and support healthcare providers in their efforts to combat the disease.

Gallant Therapeutics is an animal health biotechnology company developing allogeneic, "off-the-shelf" stem cell therapies from their stem cell platform. Gallant is also the leading provider of non-invasive stem cell banking during the spay or neuter process, opening the door to novel regenerative medical treatments formerly unavailable for non-human family members. Clinical studies demonstrate stem cell therapies help pets with a multitude of ailments, including osteoarthritis, atopic dermatitis, chronic kidney disease, and chronic stomatitis, among others. Gallant's first product helps to save cats that would die of chronic gingivostomatitis, with a robust pipeline in development for companion animals.

T-Therapeutics is a biopharmaceutical company specializing in the development of engineered soluble biologics for oncological and immunological conditions. The company utilizes a proprietary T cell receptor (TCR) discovery platform, which is based on a highly humanized mouse model. This innovative approach allows T-Therapeutics to identify TCRs that target human antigens not obtainable from human samples. The TCRs bind specific pMHC targets on target cells, facilitating the recruitment of T cells to either attack cancer cells or modulate immune responses. By leveraging advanced techniques in mouse genome engineering, single cell genomics, machine learning, and structural biology, T-Therapeutics aims to enhance treatment options for patients suffering from chronic and infectious diseases while fostering a culture of creativity and collaboration within its operations.

Eden Brew is a food and beverage company that provides a range of animal-free and precision-fermented milk and dairy products.

EpiBiologics focuses on developing antibody-based targeted therapies aimed at membrane and extracellular proteins that contribute to various diseases. The company utilizes its EpiTAC platform to create therapeutics that degrade these disease-driving proteins, addressing the underlying biology of disorders. By specializing in protein degradation, EpiBiologics enables researchers to manipulate cellular proteostasis, offering potential solutions for a wide range of medical conditions.

Ascend Gene & Cell Therapies supports manufacturing and process development projects from design through to clinical and commercial scales. They partner with biotechnology teams to embed scalable manufacturing in their operations from the beginning. They respond to customer inquiries by phone and contact form.

Companion creates technology that simplifies how owners interact with and train their dogs. Companion's proprietary technology communicates with dogs through audio, and 3D sensing systems detect and analyze the dog's movement and behaviors. With machine learning, it can adapt in real-time, calculating the best way to engage with a dog. Companion rewards the dog for desired behaviors such as sit, down, stay, and recall using positive reinforcement techniques and proprietary data and algorithms.

Switch Therapeutics is a biotechnology company established in 2020 and located in San Francisco, California. The company focuses on developing innovative RNA interference (RNAi) therapies aimed at transforming the treatment of various diseases, particularly those affecting the central nervous system and other systemic conditions with significant unmet medical needs. By integrating nucleic acid nanotechnology with RNAi science, Switch Therapeutics creates biomarker-gated genetic medicines designed to activate RNA molecules and therapies specifically in targeted cells. This targeted approach aims to enhance the effectiveness of treatments for central nervous system diseases, providing healthcare providers with advanced therapeutic options.

Onc.AI, Inc. is a San Carlos, California-based company founded in 2020 that focuses on clinical oncology. It specializes in leveraging advanced technologies such as deep learning to enhance oncology diagnostics by providing insights derived from clinical oncology data, genomics, proteomics, and radiomics. The company's comprehensive approach aims to improve treatment outcomes by offering actionable insights that aid in the decision-making process for healthcare professionals in the oncology field.

Bonum Therapeutics is a biopharmaceutical company focused on developing innovative protein-based drugs designed to treat various diseases, with a primary emphasis on cancer. The company has established a technology platform that enables the creation of drugs with regulated, context-dependent activity. These drugs are engineered to sense their local environment and transition from an inactive to an active form, allowing for targeted therapeutic effects. In addition to cancer, Bonum Therapeutics also aims to address metabolic diseases, immunological conditions, and pain management, thereby expanding its potential impact across multiple therapeutic areas.

Elemental Machines, Inc., founded in 2014 and based in Cambridge, Massachusetts, operates within the technology sector, focusing on revolutionizing science-based industries through its smart lab platform. This platform leverages artificial intelligence to provide data-driven insights that enhance laboratory operations, research, development, and manufacturing processes. By continuously monitoring equipment and environmental variables using intelligent sensors, it offers improved clarity, transparency, consistency, and repeatability. The system also sends alerts via text and email for any anomalous results, facilitating clients in refining and accelerating their work across all stages of product innovation. Through the collection of new data sets, Elemental Machines enables advanced analytics that supports experimental reproducibility and optimizes operational efficiency.

Matchpoint Therapeutics is a biotechnology company focused on developing precision covalent medicines aimed at transforming the treatment of immune diseases and other serious conditions. Utilizing its proprietary Advanced Covalent Exploration (ACE) platform, the company combines advanced chemoproteomics, machine learning, and the evolution of covalent chemistry libraries to enhance drug discovery. This innovative approach allows for a deeper exploration of the proteome, enabling the identification and targeting of new binding sites on disease-causing proteins. Matchpoint is building an emerging pipeline of novel covalent medicines, with an initial emphasis on immunology.

Faeth Therapeutics is a data-driven, evidence-based company that specializes in mechanistic understanding of the way that dietary nutrients influence tumor growth and cancer treatment. It fully focuses on matching specific diets with tumor genotypes and treatment regimens to improve the outcomes of cancer therapy. The company was founded to translate breakthrough discoveries, made by cancer research laboratories, into clinical practice. Its founding team includes some of the industry’s preeminent researchers and clinicians.

Ness builds a credit card-first wedge into healthcare. It allows its user to earn rewards for healthy purchases and access exclusive perks to complement their lifestyle. It was established in 2021 and is based in New York, United States.

Eden Brew is a food and beverage company that provides a range of animal-free and precision-fermented milk and dairy products.

Terray Therapeutics is a biotechnology company based in Pasadena, California, founded in 2018. The company specializes in developing innovative treatments for complex human diseases by integrating experimentation and computation to enhance small molecule drug discovery. Terray's unique platform employs ultra-dense microarray technology alongside artificial intelligence and synthetic chemistry to generate extensive and precise chemical datasets. This allows for a rapid design-make-test-analyze cycle, facilitating efficient exploration of chemical space and mapping biochemical interactions between small molecules and disease causes. By utilizing automation and machine learning, Terray addresses significant therapeutic challenges, ultimately guiding the next cycles of drug design and experimentation.

Faeth Therapeutics is a data-driven, evidence-based company that specializes in mechanistic understanding of the way that dietary nutrients influence tumor growth and cancer treatment. It fully focuses on matching specific diets with tumor genotypes and treatment regimens to improve the outcomes of cancer therapy. The company was founded to translate breakthrough discoveries, made by cancer research laboratories, into clinical practice. Its founding team includes some of the industry’s preeminent researchers and clinicians.

Good Therapeutics, Inc. is a biotechnology company based in Seattle, Washington, established in 2016. The company specializes in developing biotherapeutics and self-regulating drugs that provide therapeutic effects precisely when and where needed. Their innovative approach involves creating context-dependent protein drugs that can sense specific biomarkers and respond accordingly, thereby enhancing efficacy while minimizing systemic toxicity. Central to their technology is an algorithm designed to create allosterically-regulated proteins, which change shape upon binding to a biomarker, activating a therapeutic domain. Good Therapeutics is particularly focused on applications in immuno-oncology, aiming to leverage biological pathways to create therapies that maximize patient benefit without compromising safety.

Elegen is a biotechnology company founded in 2017, focused on developing microfluidic technology to advance synthetic biology. Led by Dr. Matthew Hill, Elegen aims to revolutionize the field by engineering entire genomes and creating innovative DNA synthesizers. Their technology is designed to enhance the speed and efficiency of DNA sequence testing, thereby facilitating significant progress in biomedical research and healthcare applications. Through these efforts, Elegen seeks to contribute to the rapid development of solutions that address various challenges in the life sciences sector.

Galatea Bio is a biotechnology company based in the United States, founded by Carlos Bustamante, Nicholas Katsanis, and Alexander Ioannidis. The company focuses on improving diagnostic testing and accelerating drug discovery, particularly in underserved populations that have been historically underrepresented in genetics research. Galatea Bio operates a biobank that serves as a biosample-to-bioinformatics platform, utilizing advanced algorithms and innovative analyses to enhance genomic discovery. By identifying patients at risk for severe multi-inflammatory syndromes and infections, Galatea Bio aims to develop new tests, treatments, and cures that can significantly improve healthcare outcomes for diverse populations.

GRO Biosciences is focused on developing advanced protein therapeutics by utilizing innovative technologies in computational protein design and synthetic biology. The company has created several genomically recoded strains of bacteria that enable the incorporation of non-standard amino acids into proteins. This approach enhances the potency, stability, and targeted delivery of these therapeutics. GRO Biosciences aims to apply its technology to improve treatments for a range of conditions, including diabetes, growth disorders, and autoimmunity, thereby addressing significant unmet medical needs.

BIOMILQ is a Durham, North Carolina-based startup founded in 2020 that specializes in producing nutritionally equivalent human breast milk using cultured human mammary cells. The company has developed a mammary biomanufacturing platform aimed at creating bioauthentic human milk ingredients that support better health outcomes for infants. By leveraging advanced technology, BIOMILQ provides an alternative for mothers and caregivers seeking a nutritious and sustainable feeding option, promoting essential aspects of infant development, including immune, gut, and neurological health. The company's innovative approach empowers families with a comprehensive solution for early-life nutrition.

Kingdom Supercultures specializes in the development and production of microbial cultures that assist food manufacturers in creating innovative food products. Founded in 2019 and based in Brooklyn, New York, the company offers Koji, a traditional Japanese ingredient used in various fermented foods and beverages. Their technology utilizes an extensive biobank of Generally Recognized As Safe (GRAS) microbial strains and employs automated systems to characterize and assemble these strains into new combinations. This enables the production of plant-based foods that replicate dairy flavors, low-alcohol beverages with rich taste, and effective natural preservatives. Kingdom Supercultures collaborates with clients across multiple sectors, including food, beverage, personal care, and beauty, focusing on enhancing the health and sustainability of food offerings.

UnifiHealth is reimagining how health benefits are built and delivered to small businesses. The company was founded in 2019 and based in Columbus, Ohio.

PetMedix Ltd is a veterinary biopharmaceutical company based in Cambridge, United Kingdom, focused on developing therapeutic antibody drugs for pets. Founded in 2017, the company utilizes advanced scientific methods to create innovative therapies that enhance the health and well-being of companion animals. PetMedix offers specialized platforms, including the Ky9 and Felyne transgenic mouse systems, which are designed to produce high-quality, therapeutic antibodies tailored specifically for pets. By leveraging over thirty years of expertise in drug development, PetMedix aims to provide effective medical solutions that meet the unique needs of animals, ensuring they receive appropriate care and treatment.

Cayaba Care is a maternal health company that offers comprehensive support for medium and high-risk women throughout their pregnancy and postpartum journeys. By combining virtual and in-person services, Cayaba Care provides a multidisciplinary approach led by Maternity Navigators, who are also certified doulas. These navigators work closely with clients to address various needs, including mental health, breastfeeding support, and postpartum follow-up, ensuring successful birth outcomes. The company partners with both commercial and Medicaid plans, utilizing standard and value-based care contracts to enhance the quality of care, improve the overall experience for patients, and achieve significant cost savings. Cayaba Care aims to alleviate the symptoms, pain, and anxiety associated with pregnancy, promoting a healthy and safe experience for expectant mothers.

Terray Therapeutics is a biotechnology company based in Pasadena, California, founded in 2018. The company specializes in developing innovative treatments for complex human diseases by integrating experimentation and computation to enhance small molecule drug discovery. Terray's unique platform employs ultra-dense microarray technology alongside artificial intelligence and synthetic chemistry to generate extensive and precise chemical datasets. This allows for a rapid design-make-test-analyze cycle, facilitating efficient exploration of chemical space and mapping biochemical interactions between small molecules and disease causes. By utilizing automation and machine learning, Terray addresses significant therapeutic challenges, ultimately guiding the next cycles of drug design and experimentation.

AnimalBiome specializes in personalized nutrition services focused on enhancing the gut health of dogs and cats through the science of the microbiome. The company offers microbiome tests that analyze the gut microbiome of individual pets, providing tailored nutrition recommendations based on the results. Additionally, AnimalBiome produces restorative supplements designed to introduce beneficial microbes sourced from healthy pets, helping to address microbiome imbalances. Through advanced diagnostics, including DNA sequencing, the company enables pet owners to gain insights into their pets' gut health, ultimately promoting a healthier and happier life for their animals.

Aunt Bertha picks up where Uncle Sam leaves off by making it easy to find and apply for government and charitable social service programs. By organizing the world's human service program information, people in need, and the people who help them can find programs in seconds on. They are driving down the cost of administering social service programs by providing a simple way for governments and charities to accept applications online. Aunt Bertha was founded in 2010 and headquartered in Austin, Texas.

Code Ocean is a cloud-based computational reproducibility platform that provides researchers and developers an easy way to share, discover, and run code published in academic journals and conferences. The platform provides open access to the published software code and data to view and download for everyone for free. But the real treat is that users can execute all published code without installing anything on their personal computer. Everything runs in the cloud on CPUs or GPUs according to the user needs.

Rejuvenate Bio Inc is a biotechnology company based in Brookline, Massachusetts, founded in 2017. The company focuses on developing gene therapies aimed at increasing the health and lifespan of domesticated animals, particularly dogs. Its innovative therapies utilize new DNA instructions to provide anti-aging treatments and address specific diseases in pets. The foundation of Rejuvenate Bio's research is rooted in work from the Wyss Institute at Harvard Medical School, and the company has established a gene therapy pipeline that targets chronic age-related diseases. By leveraging clinically validated gene targets and effective delivery methods, Rejuvenate Bio aims for long-lasting and well-tolerated gene expression, ultimately enhancing the quality of life for both animals and potentially humans facing chronic health challenges.

SeQure Dx specializes in providing safety data related to CRISPR gene editing therapies, focusing on both on-target and off-target effects. The company develops genomics diagnostic technologies that facilitate target profiling for gene editing, supporting the discovery, clinical development, and diagnostic processes. Its core technologies are designed to identify potential off-target sites prior to the initiation of therapy, ensuring comprehensive confirmation of actual genetic edits. This capability empowers gene editing therapeutics developers, physicians, and patients by enhancing the safety and efficacy of gene editing treatments.

UnifiHealth is reimagining how health benefits are built and delivered to small businesses. The company was founded in 2019 and based in Columbus, Ohio.

Onc.AI, Inc. is a San Carlos, California-based company founded in 2020 that focuses on clinical oncology. It specializes in leveraging advanced technologies such as deep learning to enhance oncology diagnostics by providing insights derived from clinical oncology data, genomics, proteomics, and radiomics. The company's comprehensive approach aims to improve treatment outcomes by offering actionable insights that aid in the decision-making process for healthcare professionals in the oncology field.

Nuperfect is a teeth-straightening company that focuses on invisible teeth correction. The company provides users with personal exclusive correction design solutions and precise customized invisible correction braces. Nuperfect was founded in 2019 and is based in Shenzhen, China.

Ansel Health is a developer of a health insurance platform designed for employers to improve employee benefits through a straightforward supplemental health benefits plan. The company provides insurance services that offer cash payouts to individuals diagnosed with various conditions, including those related to COVID-19. This support helps alleviate financial burdens associated with serious health issues, ensuring that employees have access to necessary resources for recovery.

Smalls is a direct-to-consumer pet food company that specializes in producing human-grade and fresh food for cats. Founded in 2017 by co-founders Matt Michaelson and Calvin Hughes, the company is headquartered in New York, New York. Smalls offers a range of cat food options, including chicken, beef, freeze-dried chicken, and turkey and duck, all prepared with high-quality ingredients. The food is made from fresh meat and a small amount of green vegetables, gently cooked to preserve nutrients and moisture. Additionally, Smalls provides customized meal kits tailored to meet the specific nutritional needs of each cat, allowing pet owners to conveniently receive healthy and fresh food delivered directly to their homes.

Base5 Genomics, Inc. is a biotechnology firm focused on developing sequencing solutions for personalized healthcare. Founded in 2018 and based in Mountain View, California, the company aims to uncover the full genomic diversity in humans and other organisms. Its innovative solutions are designed to enhance the understanding of cancer biology, DNA damage and repair, genome organization, and gene regulation. By providing detailed genomic insights, Base5 Genomics enables the medical community to offer tailored treatments that cater to individual patient needs, thereby advancing the field of personalized medicine.

Good Therapeutics, Inc. is a biotechnology company based in Seattle, Washington, established in 2016. The company specializes in developing biotherapeutics and self-regulating drugs that provide therapeutic effects precisely when and where needed. Their innovative approach involves creating context-dependent protein drugs that can sense specific biomarkers and respond accordingly, thereby enhancing efficacy while minimizing systemic toxicity. Central to their technology is an algorithm designed to create allosterically-regulated proteins, which change shape upon binding to a biomarker, activating a therapeutic domain. Good Therapeutics is particularly focused on applications in immuno-oncology, aiming to leverage biological pathways to create therapies that maximize patient benefit without compromising safety.

Kenzen, Inc. specializes in health and performance monitoring through its innovative Kenzen ECHO system, which includes a wireless smart patch designed to provide real-time feedback on vital signs, motion, and performance. The smart patch continuously monitors critical parameters to detect heat-related injuries and alert both users and safety supervisors, thereby enhancing workplace safety. Kenzen ECHO also incorporates a mobile application that delivers personalized health insights, aiding in performance improvement and injury prevention. The company, which was incorporated in 2014 and is based in New York, markets its products through various distributors, resellers, and retail locations. Its mission focuses on leveraging physiological data to predict and prevent injuries among industrial workers, ultimately boosting productivity and ensuring safer work environments.

Scratch is a financial technology company that specializes in payment processing, patient financing, and communication tools tailored for veterinary and medical practices. Its platform is utilized by approximately half of all veterinary clinics in the United States, facilitating efficient interactions and transactions between practices and their clients. Scratch's patient financing solution offers clients, including pet owners, a guaranteed financing offer in as little as 60 seconds, helping them manage medical expenses. Additionally, Scratch's payment processing tools integrate with popular practice management systems, enhancing the checkout experience for both patients and practices. This comprehensive approach supports various medical and dental practices in accessing modern financial solutions effectively.

Aunt Bertha picks up where Uncle Sam leaves off by making it easy to find and apply for government and charitable social service programs. By organizing the world's human service program information, people in need, and the people who help them can find programs in seconds on. They are driving down the cost of administering social service programs by providing a simple way for governments and charities to accept applications online. Aunt Bertha was founded in 2010 and headquartered in Austin, Texas.

Code Ocean is a cloud-based computational reproducibility platform that provides researchers and developers an easy way to share, discover, and run code published in academic journals and conferences. The platform provides open access to the published software code and data to view and download for everyone for free. But the real treat is that users can execute all published code without installing anything on their personal computer. Everything runs in the cloud on CPUs or GPUs according to the user needs.

Pawp, Inc. is a digital health clinic and telehealth platform focused on pet care, connecting pet owners with licensed veterinary professionals. Founded in 2020 and based in New York, the platform offers users unlimited 24/7 access to veterinarians, allowing for timely consultations that can often replace unnecessary in-person visits. Additionally, Pawp provides a yearly pet emergency fund of $3,000, serving as a financial safety net for unexpected veterinary expenses. By facilitating these services, Pawp aims to empower pet owners to make informed health decisions for their pets while managing costs effectively.

Scout Bio, Inc. is a biotechnology company focused on developing innovative therapies for chronic health conditions in pets, utilizing veterinary biotechnology and gene therapy. Founded in 2016 and based in Philadelphia, Pennsylvania, the company specializes in creating one-time treatments to address significant issues such as anemia linked to chronic kidney disease in cats. Scout Bio employs Adeno-associated viral vector technology to design and deliver protein and monoclonal antibody therapeutics through single intra-muscular injections. The company's mission is to apply advancements from human medicine to improve veterinary care and enhance the quality of life for pets.

Terray Therapeutics is a biotechnology company based in Pasadena, California, founded in 2018. The company specializes in developing innovative treatments for complex human diseases by integrating experimentation and computation to enhance small molecule drug discovery. Terray's unique platform employs ultra-dense microarray technology alongside artificial intelligence and synthetic chemistry to generate extensive and precise chemical datasets. This allows for a rapid design-make-test-analyze cycle, facilitating efficient exploration of chemical space and mapping biochemical interactions between small molecules and disease causes. By utilizing automation and machine learning, Terray addresses significant therapeutic challenges, ultimately guiding the next cycles of drug design and experimentation.

GRO Biosciences is focused on developing advanced protein therapeutics by utilizing innovative technologies in computational protein design and synthetic biology. The company has created several genomically recoded strains of bacteria that enable the incorporation of non-standard amino acids into proteins. This approach enhances the potency, stability, and targeted delivery of these therapeutics. GRO Biosciences aims to apply its technology to improve treatments for a range of conditions, including diabetes, growth disorders, and autoimmunity, thereby addressing significant unmet medical needs.

PetMedix Ltd is a veterinary biopharmaceutical company based in Cambridge, United Kingdom, focused on developing therapeutic antibody drugs for pets. Founded in 2017, the company utilizes advanced scientific methods to create innovative therapies that enhance the health and well-being of companion animals. PetMedix offers specialized platforms, including the Ky9 and Felyne transgenic mouse systems, which are designed to produce high-quality, therapeutic antibodies tailored specifically for pets. By leveraging over thirty years of expertise in drug development, PetMedix aims to provide effective medical solutions that meet the unique needs of animals, ensuring they receive appropriate care and treatment.

Good Therapeutics, Inc. is a biotechnology company based in Seattle, Washington, established in 2016. The company specializes in developing biotherapeutics and self-regulating drugs that provide therapeutic effects precisely when and where needed. Their innovative approach involves creating context-dependent protein drugs that can sense specific biomarkers and respond accordingly, thereby enhancing efficacy while minimizing systemic toxicity. Central to their technology is an algorithm designed to create allosterically-regulated proteins, which change shape upon binding to a biomarker, activating a therapeutic domain. Good Therapeutics is particularly focused on applications in immuno-oncology, aiming to leverage biological pathways to create therapies that maximize patient benefit without compromising safety.

MollyBox is a subscription-based e-commerce platform that caters to pet owners, specifically focusing on cats. Founded in 2015 by Yifu Sun and Yi Ju, the company is headquartered in Shanghai, China. MollyBox provides a monthly themed box that includes a selection of natural cat food and toys, allowing customers to conveniently receive these products on a regular basis. In addition to subscription options, customers can also purchase individual items, enhancing the accessibility of their offerings. Through this model, MollyBox aims to meet the needs of pet owners by delivering quality products directly to their homes.

Girihlet Inc. is a genetic-sequencing company based in Oakland, California, established in 2012. The company specializes in providing rapid and accurate deep sequencing services, focusing on non-canonical genomics solutions. Girihlet has developed patented technologies for profiling T cell receptors and sequencing mitochondrial DNA, utilizing novel, bias-free methods to analyze these genetic components. This approach aims to harness the potential of T cell receptors and mtDNA as biomarkers for diagnostics across various disorders, particularly those driven by T-cell-related autoimmune conditions. By employing deep sequencing and machine learning, Girihlet seeks to decode individual immune responses and guide effective therapeutic strategies, thereby contributing significantly to both clinical applications and advanced research in immunology.

Rejuvenate Bio Inc is a biotechnology company based in Brookline, Massachusetts, founded in 2017. The company focuses on developing gene therapies aimed at increasing the health and lifespan of domesticated animals, particularly dogs. Its innovative therapies utilize new DNA instructions to provide anti-aging treatments and address specific diseases in pets. The foundation of Rejuvenate Bio's research is rooted in work from the Wyss Institute at Harvard Medical School, and the company has established a gene therapy pipeline that targets chronic age-related diseases. By leveraging clinically validated gene targets and effective delivery methods, Rejuvenate Bio aims for long-lasting and well-tolerated gene expression, ultimately enhancing the quality of life for both animals and potentially humans facing chronic health challenges.

Scratch is a financial technology company that specializes in payment processing, patient financing, and communication tools tailored for veterinary and medical practices. Its platform is utilized by approximately half of all veterinary clinics in the United States, facilitating efficient interactions and transactions between practices and their clients. Scratch's patient financing solution offers clients, including pet owners, a guaranteed financing offer in as little as 60 seconds, helping them manage medical expenses. Additionally, Scratch's payment processing tools integrate with popular practice management systems, enhancing the checkout experience for both patients and practices. This comprehensive approach supports various medical and dental practices in accessing modern financial solutions effectively.

Kenzen, Inc. specializes in health and performance monitoring through its innovative Kenzen ECHO system, which includes a wireless smart patch designed to provide real-time feedback on vital signs, motion, and performance. The smart patch continuously monitors critical parameters to detect heat-related injuries and alert both users and safety supervisors, thereby enhancing workplace safety. Kenzen ECHO also incorporates a mobile application that delivers personalized health insights, aiding in performance improvement and injury prevention. The company, which was incorporated in 2014 and is based in New York, markets its products through various distributors, resellers, and retail locations. Its mission focuses on leveraging physiological data to predict and prevent injuries among industrial workers, ultimately boosting productivity and ensuring safer work environments.

Elemental Machines, Inc., founded in 2014 and based in Cambridge, Massachusetts, operates within the technology sector, focusing on revolutionizing science-based industries through its smart lab platform. This platform leverages artificial intelligence to provide data-driven insights that enhance laboratory operations, research, development, and manufacturing processes. By continuously monitoring equipment and environmental variables using intelligent sensors, it offers improved clarity, transparency, consistency, and repeatability. The system also sends alerts via text and email for any anomalous results, facilitating clients in refining and accelerating their work across all stages of product innovation. Through the collection of new data sets, Elemental Machines enables advanced analytics that supports experimental reproducibility and optimizes operational efficiency.

GRO Biosciences is focused on developing advanced protein therapeutics by utilizing innovative technologies in computational protein design and synthetic biology. The company has created several genomically recoded strains of bacteria that enable the incorporation of non-standard amino acids into proteins. This approach enhances the potency, stability, and targeted delivery of these therapeutics. GRO Biosciences aims to apply its technology to improve treatments for a range of conditions, including diabetes, growth disorders, and autoimmunity, thereby addressing significant unmet medical needs.

Kenzen, Inc. specializes in health and performance monitoring through its innovative Kenzen ECHO system, which includes a wireless smart patch designed to provide real-time feedback on vital signs, motion, and performance. The smart patch continuously monitors critical parameters to detect heat-related injuries and alert both users and safety supervisors, thereby enhancing workplace safety. Kenzen ECHO also incorporates a mobile application that delivers personalized health insights, aiding in performance improvement and injury prevention. The company, which was incorporated in 2014 and is based in New York, markets its products through various distributors, resellers, and retail locations. Its mission focuses on leveraging physiological data to predict and prevent injuries among industrial workers, ultimately boosting productivity and ensuring safer work environments.

Somatix, Inc. specializes in developing real-time wearable remote patient monitoring (RPM) solutions aimed at enhancing healthcare delivery. Founded in 2015 and based in New York, the company utilizes patented gesture detection technology, artificial intelligence, and machine learning algorithms to analyze gesture data from various wearable devices. Its flagship offerings include SafeBeing, designed for elderly monitoring, and SmokeBeat, which aids in smoking cessation. By passively collecting data on users' hydration, sleep, activity levels, and medication adherence, Somatix's platform provides healthcare providers with critical clinical insights. This facilitates early detection of health issues, enhances care management, and ensures continuous engagement with patients, ultimately improving overall wellbeing.

SchoolCare is a digital health platform dedicated to enhancing pediatric healthcare in K-12 public schools. By providing free health technology, it assists school nurses in delivering effective care and ensuring student safety. The platform captures essential health information, including student medical charts, medications, and immunizations, while facilitating communication between schools, families, and healthcare providers. This connectivity allows for timely alerts about health events and supports the efficient operation of public school health programs. By addressing gaps in traditional care coordination, SchoolCare aims to improve health outcomes for children, ensuring that they receive consistent and comprehensive care throughout their school experience.