Define Ventures

Define Ventures is an early-stage venture capital firm based in San Francisco, California, founded in 2019. The firm specializes in investing exclusively in digital health companies, aiming to support entrepreneurs who are dedicated to transforming healthcare through innovative digital solutions. By partnering with these entrepreneurs, Define Ventures seeks to leverage their expertise and insights to redefine the healthcare landscape.

Chuka Esiobu

Senior Associate

Garrett Howard

Senior Associate and Investor

Lynne Chou O'Keefe

Founder and Managing Partner

Chirag Shah

Partner

Hong Truong

Principal

46 past transactions

Marit Health

Seed Round in 2025
Marit Health is a platform and community for clinicians to thrive in their careers

Layer Health

Series A in 2025
Layer Health focuses on resolving the healthcare information problem by utilizing artificial intelligence to execute any clinical, administrative, or research work that involves chart review from unstructured data.

Blackbird Health

Series A in 2024
Blackbird Health is a mental health clinic that supports children and young adults facing social, developmental, and academic difficulties. The practice offers both in-person and virtual therapy options, making it accessible to a broader range of clients. Blackbird Health employs a holistic approach to mental health care, aiming to address the overall well-being of their clients.

9amHealth

Series A in 2024
9amHealth is a healthcare service provider that aims to deliver comprehensive medical support for chronic conditions such as diabetes, hypertension, and hyperlipidemia. The company offers personalized care plans, prescription medication, at-home lab tests, and unlimited virtual visits, ensuring that patients have direct access to affordable and compassionate care. By redesigning all care elements into a single digital service, 9amHealth caters to the modern realities of patients' lives, making healthcare always available and convenient, even for those without insurance. Its focus on chronic conditions highlights its commitment to improving the health and well-being of customers in the United States.

Cohere Health

Series C in 2024
Cohere Health, Inc. is a healthcare technology company based in Boston, Massachusetts, established in 2019. The company focuses on enhancing healthcare delivery by creating a platform that facilitates collaboration among various stakeholders, including patients, providers, and payers. Cohere Health specializes in intelligent prior authorization, which aligns the needs of physicians and health plans through a customizable service. By utilizing artificial intelligence, machine learning, and real-time analytics, the company automates the prior authorization process, enabling efficient utilization management. This approach aims to simplify the complexities of the healthcare system, improve communication, and ultimately enhance patient outcomes throughout the healthcare journey.

Datalogz

Series A in 2023
Datalogz is a platform focused on data discovery and understanding, designed to reduce data ambiguity from various sources. Its offerings include a data catalog, data lineage, data governance, and a data glossary, all aimed at enhancing the efficiency of data management. The platform enables data scientists and analysts to utilize AI-powered recommendations, which help improve project quality and streamline workflows. By providing these tools, Datalogz seeks to facilitate clearer data insights and support better decision-making in data-related projects.

RepubliK GG

Seed Round in 2023
RepubliK GG specializes in developing a suite of tools for creators. It helps creators to unlock a wealth of untapped opportunities that cannot be reached within the confines of current social platforms.

Laudio

Series B in 2023
Laudio LLC is a Boston-based company that operates a SaaS platform focused on healthcare leadership and staff relationship management. Founded in 2017, the platform leverages artificial intelligence and predictive analytics to enhance employee engagement and retention while minimizing burnout. It provides healthcare executives and managers with an integrated management system that bridges the gap between information and actionable insights. By digitizing workflows, Laudio enables managers to interact with staff members more frequently and effectively, offering proactive interventions to address risk factors in real time. This approach not only improves team dynamics but also helps organizations reduce turnover costs and enhance overall operational efficiency.

Intrinsic

Venture Round in 2023
Intrinsic Brands is an eCommerce acquisition and growth platform uniquely focused on digital-first health and wellness brands.

Crescendo Health

Seed Round in 2023
Crescendo Health is a digital health company focused on transforming the collection and utilization of patient health data to enhance clinical research. The company builds relationships with patients by obtaining their consent to gather health information, which is then curated for trial sponsors, offering a comprehensive and longitudinal overview of patient health. Crescendo Health operates a public benefit platform that assembles individual health stories while ensuring privacy, allowing patients to maintain access to their personal health records or request deletion of their data. The information is securely stored in a cloud-based database, enabling healthcare providers and researchers to gain insights into full health journeys and improve the design of clinical trials. Founded by experienced healthcare executives, the team combines expertise from research, technology, and the provider community.

UpStream Care

Series B in 2022
UpStream Care is a primary care services and technology company providing physicians with support and systems. It allows physicians to focus on what they and their patients value the most. Their intelligent technology platform, which integrates with all physician EMRs and provides an elegant workflow for all care coordination activities, augments this in-person clinical support.

FOLX

Series B in 2022
FOLX Health is a telehealth platform based in Boston, Massachusetts, that specializes in providing digital healthcare services for the LGBTQIA+ community. Launched in 2020, the platform creates a medical service marketplace specifically designed for queer and trans individuals. FOLX Health offers access to a network of clinicians who understand the unique needs of this community, focusing on services such as gender-affirming hormone therapy, sexual health, and family creation. The platform also provides virtual consultations, discreet delivery of at-home medication kits, and general medical services, aiming to eliminate the barriers and stigma often encountered in traditional healthcare settings. By prioritizing the health and well-being of LGBTQIA+ individuals, FOLX Health fosters a supportive environment for patients to manage their health needs.

Soda Health

Series A in 2022
Soda Health is a healthcare technology company founded in 2021 and based in Chicago, Illinois. The company focuses on addressing health inequities by leveraging social determinants of health. It offers a technology platform designed to assist individuals in identifying, accessing, and funding the resources necessary for a healthy life. By providing a system for administering and reimbursing personalized benefits, Soda Health enables customers to effectively bridge the gap between medical claims and retail payments, ultimately promoting better health outcomes.

Fair Square Medicare

Series A in 2022
Fair Square Medicare provides a consumer-friendly way for seniors to buy health insurance. The company offers a quantitative and systematic approach to finding coverage.Their software analyzes the plans available to customers and finds the few worth considering. Then one of their licensed partner agents walks customers through the pros and cons of each option.

Concert Health

Series B in 2022
Concert Health, Inc. is a company that develops and operates an online platform designed to connect physicians with therapists and psychiatrists, facilitating the integration of behavioral health services into primary care practices. Founded in 2016 and headquartered in San Diego, California, the company provides a range of services including remote clinical staffing with behavioral care managers and psychiatric consultants, as well as tools for registry, screening, workflow management, and reimbursement. Concert Health emphasizes evidence-based care by assisting medical groups in implementing shared care plans that address both physical and mental health needs. By working closely with primary care teams, Concert Health aims to enhance the quality of behavioral health care through effective documentation and billing support, ultimately improving patient outcomes.

Waltz Health

Series A in 2022
Waltz Health is focused on enhancing the pharmaceutical supply chain by collaborating with consumers, payers, and pharmacies to develop innovative, technology-driven solutions for pricing, distribution, and prescription of medications. The company creates AI-driven marketplaces that aim to reduce costs and provide valuable insights for users, facilitating informed decision-making in prescription care. By offering consumer tools designed to empower individuals and help payers manage their pharmacy benefits, Waltz Health strives to improve accessibility and affordability in the healthcare sector.

9amHealth

Series A in 2022
9amHealth is a healthcare service provider that aims to deliver comprehensive medical support for chronic conditions such as diabetes, hypertension, and hyperlipidemia. The company offers personalized care plans, prescription medication, at-home lab tests, and unlimited virtual visits, ensuring that patients have direct access to affordable and compassionate care. By redesigning all care elements into a single digital service, 9amHealth caters to the modern realities of patients' lives, making healthcare always available and convenient, even for those without insurance. Its focus on chronic conditions highlights its commitment to improving the health and well-being of customers in the United States.

Found

Series B in 2021
Found is dedicated to improving people’s overall wellbeing by making evidence-based weight loss accessible and affordable. The company was founded in 2019 and is headquartered in San Francisco, California, United States.

Lightship

Series C in 2021
Lightship is a company founded in 2018 that focuses on enhancing access, choice, and equity in clinical trials through decentralized and hybrid clinical services. By leveraging innovations in digital health and technology, Lightship aims to transform the clinical research landscape by improving patient experiences, retention, and trial diversity. The company moves beyond traditional research centers to make clinical studies more accessible, allowing medical research organizations to overcome the barriers and inefficiencies associated with conventional clinical trial models. Its mission centers on placing patients at the forefront, ensuring that clinical research is designed to meet the needs of diverse populations globally.

Centivo

Venture Round in 2021
Centivo is a new type of health plan administrator that allows self-funded employers and clinicians to join forces and deliver high quality, affordable healthcare to their employees. An alternative to traditional insurance carriers or third-party administrators, Centivo offers the technology, network, claims processing, customer support, and population health management to fully administer health benefits for all or a portion of an employee population. The Centivo model emphasizes the partnership between individuals and their primary care team as the proper model to coordinate healthcare needs. Centivo’s clinical partners are dedicated to controlling costs and helping members navigate the healthcare system, aided by personalized patient/doctor matching tools. Members are rewarded for working with their primary care team and choosing high-value care and are supported through a user-friendly app and their concierge. Employers get an ally that diligently roots out waste and is accountable for performance. It was formed in 2017 and headquartered in New York, United States.

9amHealth

Seed Round in 2021
9amHealth is a healthcare service provider that aims to deliver comprehensive medical support for chronic conditions such as diabetes, hypertension, and hyperlipidemia. The company offers personalized care plans, prescription medication, at-home lab tests, and unlimited virtual visits, ensuring that patients have direct access to affordable and compassionate care. By redesigning all care elements into a single digital service, 9amHealth caters to the modern realities of patients' lives, making healthcare always available and convenient, even for those without insurance. Its focus on chronic conditions highlights its commitment to improving the health and well-being of customers in the United States.

Tia

Series B in 2021
Tia, Inc. is a health advisory platform focused on providing personalized and data-driven support for women's health and lifestyle. Founded in 2015 and headquartered in New York City with an additional office in San Francisco, Tia offers a mobile application that features services such as birth control recommendations, sexual health advice, symptom tracking, and the ability to locate nearby healthcare providers. The platform empowers women to manage their health by allowing them to schedule in-person appointments and access virtual care. Tia aims to address the unique needs of women in the healthcare system, recognizing that they control a significant portion of healthcare spending in the U.S. The company is supported by various venture funds, highlighting its commitment to building a healthcare model that prioritizes female patients.

Intrinsic

Series A in 2021
Intrinsic Brands is an eCommerce acquisition and growth platform uniquely focused on digital-first health and wellness brands.

Cohere Health

Series B in 2021
Cohere Health, Inc. is a healthcare technology company based in Boston, Massachusetts, established in 2019. The company focuses on enhancing healthcare delivery by creating a platform that facilitates collaboration among various stakeholders, including patients, providers, and payers. Cohere Health specializes in intelligent prior authorization, which aligns the needs of physicians and health plans through a customizable service. By utilizing artificial intelligence, machine learning, and real-time analytics, the company automates the prior authorization process, enabling efficient utilization management. This approach aims to simplify the complexities of the healthcare system, improve communication, and ultimately enhance patient outcomes throughout the healthcare journey.

DexCare

Series A in 2021
DexCare is a Seattle-based provider of a platform-as-a-service designed to optimize health system capacity and demand across various lines of care. Established in 2021, the company offers a solution that transforms traditional patient-to-provider relationships into a scalable digital experience. This platform enhances patient access to the appropriate care settings, enabling healthcare institutions to attract new patients, boost revenue, and improve overall satisfaction. Additionally, DexCare's approach leads to significant cost savings while ensuring that patients receive timely and effective care.

Unite Us

Series C in 2021
Unite Us is a veteran-led technology company that specializes in creating coordinated care networks that connect health and social service providers. Founded in 2013 by veterans Dan Brillman and Taylor Justice in New York, the company focuses on integrating social determinants of health into patient care to enhance the delivery of services. Its platform enables providers to securely send and receive referrals, track each individual's health journey, and report on outcomes across various services. By fostering a centralized and collaborative ecosystem, Unite Us empowers communities to move beyond traditional resource directories, allowing them to effectively measure impact and improve health outcomes at scale.

Found

Series A in 2021
Found is dedicated to improving people’s overall wellbeing by making evidence-based weight loss accessible and affordable. The company was founded in 2019 and is headquartered in San Francisco, California, United States.

Story Health

Seed Round in 2020
Story Health Corporation, founded in 2020 and based in Saratoga, California, develops advanced virtualized clinical care software tools aimed at aiding healthcare specialists, particularly neurologists and primary care physicians. The company offers a comprehensive healthcare technology platform that includes virtual patient programs, therapy management, and analytics designed to bridge the gap between clinical evidence and patient experiences. By utilizing data from high-frequency sources, Story Health empowers clinicians to better understand medical situations and make informed decisions regarding the physiological impacts of diseases and therapies. Through its innovative approach, Story Health enhances the ability of specialists to deliver effective patient care.

Centivo

Series B in 2020
Centivo is a new type of health plan administrator that allows self-funded employers and clinicians to join forces and deliver high quality, affordable healthcare to their employees. An alternative to traditional insurance carriers or third-party administrators, Centivo offers the technology, network, claims processing, customer support, and population health management to fully administer health benefits for all or a portion of an employee population. The Centivo model emphasizes the partnership between individuals and their primary care team as the proper model to coordinate healthcare needs. Centivo’s clinical partners are dedicated to controlling costs and helping members navigate the healthcare system, aided by personalized patient/doctor matching tools. Members are rewarded for working with their primary care team and choosing high-value care and are supported through a user-friendly app and their concierge. Employers get an ally that diligently roots out waste and is accountable for performance. It was formed in 2017 and headquartered in New York, United States.

MedArrive

Seed Round in 2020
MedArrive, Inc. operates a software-as-a-service health platform that facilitates the extension of healthcare services into patients' homes. Based in New York, the company connects healthcare providers with a network of emergency medical professionals, allowing for a seamless integration of in-home care and telemedicine. This innovative approach aims to serve vulnerable populations by improving access to high-quality healthcare while reducing overall costs. MedArrive's platform consolidates clinical data into electronic medical records and enhances communication and billing processes, ultimately fostering better patient outcomes and encouraging self-advocacy among patients. By utilizing an underemployed workforce, MedArrive aims to bridge the virtual care gap, ensuring continuity of care and re-engaging patients in primary healthcare services.

Cohere Health

Series A in 2020
Cohere Health, Inc. is a healthcare technology company based in Boston, Massachusetts, established in 2019. The company focuses on enhancing healthcare delivery by creating a platform that facilitates collaboration among various stakeholders, including patients, providers, and payers. Cohere Health specializes in intelligent prior authorization, which aligns the needs of physicians and health plans through a customizable service. By utilizing artificial intelligence, machine learning, and real-time analytics, the company automates the prior authorization process, enabling efficient utilization management. This approach aims to simplify the complexities of the healthcare system, improve communication, and ultimately enhance patient outcomes throughout the healthcare journey.

Tia

Series A in 2020
Tia, Inc. is a health advisory platform focused on providing personalized and data-driven support for women's health and lifestyle. Founded in 2015 and headquartered in New York City with an additional office in San Francisco, Tia offers a mobile application that features services such as birth control recommendations, sexual health advice, symptom tracking, and the ability to locate nearby healthcare providers. The platform empowers women to manage their health by allowing them to schedule in-person appointments and access virtual care. Tia aims to address the unique needs of women in the healthcare system, recognizing that they control a significant portion of healthcare spending in the U.S. The company is supported by various venture funds, highlighting its commitment to building a healthcare model that prioritizes female patients.

FOLX

Venture Round in 2020
FOLX Health is a telehealth platform based in Boston, Massachusetts, that specializes in providing digital healthcare services for the LGBTQIA+ community. Launched in 2020, the platform creates a medical service marketplace specifically designed for queer and trans individuals. FOLX Health offers access to a network of clinicians who understand the unique needs of this community, focusing on services such as gender-affirming hormone therapy, sexual health, and family creation. The platform also provides virtual consultations, discreet delivery of at-home medication kits, and general medical services, aiming to eliminate the barriers and stigma often encountered in traditional healthcare settings. By prioritizing the health and well-being of LGBTQIA+ individuals, FOLX Health fosters a supportive environment for patients to manage their health needs.

Found

Seed Round in 2020
Found is dedicated to improving people’s overall wellbeing by making evidence-based weight loss accessible and affordable. The company was founded in 2019 and is headquartered in San Francisco, California, United States.

Verana Health

Series D in 2020
Verana Health, Inc. is a digital health company based in San Francisco, California, that specializes in transforming healthcare data into actionable insights. Founded in 2008 and formerly known as Digisight Technologies, the company connects healthcare providers with patients through innovative solutions. Its flagship product, SightBook, is a mobile application that enables users to test their vision and share results with their physicians in real-time, facilitating timely appointments and treatments. Verana Health manages data from over 20,000 healthcare providers and 70 electronic health record systems, leveraging its AI-enhanced platform, VeraQ™, to create a robust healthcare data ecosystem. By utilizing advanced analytics on curated datasets, Verana Health supports life sciences partners in improving clinical research and enhancing patient care outcomes.

Lightship

Series B in 2020
Lightship is a company founded in 2018 that focuses on enhancing access, choice, and equity in clinical trials through decentralized and hybrid clinical services. By leveraging innovations in digital health and technology, Lightship aims to transform the clinical research landscape by improving patient experiences, retention, and trial diversity. The company moves beyond traditional research centers to make clinical studies more accessible, allowing medical research organizations to overcome the barriers and inefficiencies associated with conventional clinical trial models. Its mission centers on placing patients at the forefront, ensuring that clinical research is designed to meet the needs of diverse populations globally.

Unite Us

Series B in 2019
Unite Us is a veteran-led technology company that specializes in creating coordinated care networks that connect health and social service providers. Founded in 2013 by veterans Dan Brillman and Taylor Justice in New York, the company focuses on integrating social determinants of health into patient care to enhance the delivery of services. Its platform enables providers to securely send and receive referrals, track each individual's health journey, and report on outcomes across various services. By fostering a centralized and collaborative ecosystem, Unite Us empowers communities to move beyond traditional resource directories, allowing them to effectively measure impact and improve health outcomes at scale.

Tia

Seed Round in 2019
Tia, Inc. is a health advisory platform focused on providing personalized and data-driven support for women's health and lifestyle. Founded in 2015 and headquartered in New York City with an additional office in San Francisco, Tia offers a mobile application that features services such as birth control recommendations, sexual health advice, symptom tracking, and the ability to locate nearby healthcare providers. The platform empowers women to manage their health by allowing them to schedule in-person appointments and access virtual care. Tia aims to address the unique needs of women in the healthcare system, recognizing that they control a significant portion of healthcare spending in the U.S. The company is supported by various venture funds, highlighting its commitment to building a healthcare model that prioritizes female patients.
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