SFPI-FPIM

Axelera AI specializes in developing hardware and software platforms designed to accelerate artificial intelligence tasks, particularly for edge computing. Its flagship product, the Metis™ AI Platform, integrates both hardware and software components to deliver high-performance, energy-efficient AI inference solutions. The company is headquartered in Eindhoven with R&D offices in Belgium, Switzerland, and Italy.

EyeD Pharma SA is a pharmaceutical company based in Liège, Belgium, specializing in the development and commercialization of innovative drug products for ophthalmology. The company focuses primarily on the treatment of glaucoma, a condition historically managed with daily eye drops. EyeD Pharma aims to enhance the quality of life for patients by reducing the side effects associated with traditional therapies. In collaboration with ophthalmologists, the company offers new treatment options and surgical products that improve clinical practices and provide therapeutic assistance that is currently lacking in the market. Through its efforts, EyeD Pharma seeks to advance the standard of care in ophthalmology.

PDC*line Pharma is a French-Belgium clinical-stage biotech company developing active immunotherapies for cancer using its proprietary Plasmacytoid Dendritic Cell line, PDC*line. These therapies aim to stimulate potent and scalable antitumor immune responses.

Imcyse SA is a clinical-stage biopharmaceutical company based in Liège, Belgium, specializing in innovative immunotherapeutic solutions aimed at treating severe chronic autoimmune diseases. Founded in 2010, Imcyse is pioneering a unique technology platform that employs Imotopes™, specifically modified peptides that target immune cells responsible for organ damage. This approach facilitates the generation of cytolytic CD4 T-cells, which selectively eliminate antigen-presenting cells and autoantigen-specific lymphocytes, thereby addressing diseases with limited treatment options. The company has shown proof of concept across various indications and has completed its initial clinical trial for type 1 diabetes, yielding promising outcomes. In addition to type 1 diabetes, Imcyse is actively developing a pipeline of therapies for multiple autoimmune diseases, aiming to provide effective treatment while preserving overall immune defense.

Endo Tools Therapeutics is a medical device company focused on gastroenterology, developing and manufacturing therapeutic devices and the ENDOMINA open platform that supports therapeutic endoscopic procedures. Founded in 2008 and based in Belgium, the company develops catheters with therapeutic channels and increased degrees of freedom for interventional gastro-enterology, as well as tools for endoscopic suturing and tissue apposition. Its devices aim to treat obesity, digestive tract tumors, and diabetes by enabling minimally invasive surgical endoscopy.

Miracor Medical develops cardiovascular medical devices, notably the PiCSO impulse system, a pressure‑controlled intermittent coronary sinus occlusion device designed to improve microvascular perfusion and cardiac function after acute myocardial infarction. The system supports treatment of myocardial infarction and can be used in surgical settings such as coronary artery bypass grafting to facilitate perfusion improvements. Founded in 2008, the company is based in Awans, Belgium, with a presence in Vienna, Austria.

ExeVir Bio BV is a Belgian biotechnology company founded in 2020 and headquartered in Zwijnaarde. The company specializes in developing single-domain antibody-based therapies aimed at preventing viral infections. Utilizing a llama-derived antibody technology platform, ExeVir Bio focuses on creating robust antiviral treatments, particularly targeting coronaviruses. One of its key products, VHH72-FC, binds to a conserved region of the SARS-CoV-2 spike protein, which is crucial for the virus's entry into human cells. The company has established a rapid response platform for antivirals, allowing for a quick adaptation to emerging health threats through a streamlined process for generating drug candidates. Their protein-based therapeutics are designed to be stable, cost-effective, and accessible on a global scale, addressing significant public health challenges posed by viral infections.

iTeos Therapeutics is a biotechnology company focused on immuno-oncology, developing cancer therapies that target the tumor microenvironment to overcome immune suppression and enhance efficacy of existing treatments. The company pursues small molecule and antibody approaches, including EOS-850, a small molecule antagonist of the adenosine A2A receptor, and EOS-448, an antagonist of TIGIT, with early-stage clinical programs designed to restore immune activity against tumors. By modulating metabolic and immune pathways within the tumor microenvironment, iTeos aims to improve responses across cancer types and complement immune checkpoint therapies.

iSTAR Medical specializes in developing ophthalmic implants made from biomaterials. Its flagship product is the STARflo glaucoma implant, a non-degradable, precision-pore device designed to reduce intraocular pressure in open angle glaucoma patients by enhancing natural fluid outflow. The company's products are sold through distributors worldwide and it operates from its eco-friendly R&D and manufacturing facility near Namur, Belgium.

Ninepointfive is a venture capital investment firm based in Antwerp, Belgium, founded in 2019. It co-invests with corporate partners to support tech startups from pre-seed to maturity, combining venture capital with corporate acceleration to drive growth. The firm works with brands such as Beiersdorf, Telenet, and Agfa to provide strategic value, resources, and market access for portfolio companies. Ninepointfive focuses on sectors including energy, information technology, B2B software as a service, and materials and resources, seeking startups with scalable technology and practical applications. By leveraging corporate networks and investment expertise, it helps founders move from early validation to scale in a pragmatic, value-driven approach.

Unifly is a developer of unmanned traffic management software focused on the secure integration of drones into global airspace. Founded in 2015 by aerospace experts, the company emerged from a vision shared by air traffic controllers who recognized the need for effective management of the increasing number of drones. Unifly's award-winning platform connects authorities and drone operators, allowing for real-time monitoring and management of drone traffic, while providing pilots with essential information regarding the legal status of their flights. The platform is already utilized by national authorities in Germany, Denmark, Austria, and Belgium, and Unifly is also active in the United States and several projects worldwide, including Africa and Asia. By fostering collaboration with various stakeholders, Unifly aims to enhance airspace safety and facilitate the seamless integration of drones into everyday life, addressing critical concerns regarding safety and oversight in both recreational and commercial drone activities.

Imcyse SA is a clinical-stage biopharmaceutical company based in Liège, Belgium, specializing in innovative immunotherapeutic solutions aimed at treating severe chronic autoimmune diseases. Founded in 2010, Imcyse is pioneering a unique technology platform that employs Imotopes™, specifically modified peptides that target immune cells responsible for organ damage. This approach facilitates the generation of cytolytic CD4 T-cells, which selectively eliminate antigen-presenting cells and autoantigen-specific lymphocytes, thereby addressing diseases with limited treatment options. The company has shown proof of concept across various indications and has completed its initial clinical trial for type 1 diabetes, yielding promising outcomes. In addition to type 1 diabetes, Imcyse is actively developing a pipeline of therapies for multiple autoimmune diseases, aiming to provide effective treatment while preserving overall immune defense.

Endo Tools Therapeutics is a medical device company focused on gastroenterology, developing and manufacturing therapeutic devices and the ENDOMINA open platform that supports therapeutic endoscopic procedures. Founded in 2008 and based in Belgium, the company develops catheters with therapeutic channels and increased degrees of freedom for interventional gastro-enterology, as well as tools for endoscopic suturing and tissue apposition. Its devices aim to treat obesity, digestive tract tumors, and diabetes by enabling minimally invasive surgical endoscopy.

Miracor Medical develops cardiovascular medical devices, notably the PiCSO impulse system, a pressure‑controlled intermittent coronary sinus occlusion device designed to improve microvascular perfusion and cardiac function after acute myocardial infarction. The system supports treatment of myocardial infarction and can be used in surgical settings such as coronary artery bypass grafting to facilitate perfusion improvements. Founded in 2008, the company is based in Awans, Belgium, with a presence in Vienna, Austria.

iTeos Therapeutics is a biotechnology company focused on immuno-oncology, developing cancer therapies that target the tumor microenvironment to overcome immune suppression and enhance efficacy of existing treatments. The company pursues small molecule and antibody approaches, including EOS-850, a small molecule antagonist of the adenosine A2A receptor, and EOS-448, an antagonist of TIGIT, with early-stage clinical programs designed to restore immune activity against tumors. By modulating metabolic and immune pathways within the tumor microenvironment, iTeos aims to improve responses across cancer types and complement immune checkpoint therapies.

Air Belgium S.A., established in 1979 and headquartered in Mont-Saint-Guibert, Belgium, specializes in passenger air transportation with a focus on intercontinental flights between Belgium and select destinations in Asia, including Hong Kong. The airline operates a diverse fleet equipped with economy, premium, and business class seating, catering to various passenger needs. In addition to providing comfortable in-flight experiences, Air Belgium also accommodates travelers with pets and children, and offers onboard catering services. The company is committed to delivering quality air travel at competitive prices, ensuring an enjoyable journey for its customers.

Miracor Medical develops cardiovascular medical devices, notably the PiCSO impulse system, a pressure‑controlled intermittent coronary sinus occlusion device designed to improve microvascular perfusion and cardiac function after acute myocardial infarction. The system supports treatment of myocardial infarction and can be used in surgical settings such as coronary artery bypass grafting to facilitate perfusion improvements. Founded in 2008, the company is based in Awans, Belgium, with a presence in Vienna, Austria.

PDC*line Pharma is a French-Belgium clinical-stage biotech company developing active immunotherapies for cancer using its proprietary Plasmacytoid Dendritic Cell line, PDC*line. These therapies aim to stimulate potent and scalable antitumor immune responses.

iSTAR Medical specializes in developing ophthalmic implants made from biomaterials. Its flagship product is the STARflo glaucoma implant, a non-degradable, precision-pore device designed to reduce intraocular pressure in open angle glaucoma patients by enhancing natural fluid outflow. The company's products are sold through distributors worldwide and it operates from its eco-friendly R&D and manufacturing facility near Namur, Belgium.

iTeos Therapeutics is a biotechnology company focused on immuno-oncology, developing cancer therapies that target the tumor microenvironment to overcome immune suppression and enhance efficacy of existing treatments. The company pursues small molecule and antibody approaches, including EOS-850, a small molecule antagonist of the adenosine A2A receptor, and EOS-448, an antagonist of TIGIT, with early-stage clinical programs designed to restore immune activity against tumors. By modulating metabolic and immune pathways within the tumor microenvironment, iTeos aims to improve responses across cancer types and complement immune checkpoint therapies.