Creative Destruction Lab (CDL)

Founded in 2018, Milk Moovement is a Canadian software company specializing in dairy supply chain management. It offers a cloud-based platform that tracks milk pick-ups, monitors production, and provides actionable intelligence to optimize processes and maximize profitability.

Clinia specializes in AI-powered infrastructure for personalized healthcare navigation. It enables health organizations to integrate and deploy tailored navigation systems within their digital platforms, enhancing resource discovery and improving care team efficiency.

Founded in 2020, 3D BioFibR Inc. specializes in manufacturing biomaterials, focusing on producing high-value biofibers such as spider silk, collagen, and chitosan. The company serves global markets including biomedical engineering, green textiles, defense, and aerospace engineering. Its products include 3D tissue cultures and collagen tendons for biomedical research.

Lucent Biosciences specializes in the development of innovative biofertilizers aimed at enhancing agricultural sustainability. The company offers a unique class of micronutrient fertilizers that promote higher crop yields and nutrient levels while being environmentally friendly. Their products are designed to improve soil health and sequester carbon, contributing to climate-positive farming practices. By utilizing sustainable bioactive crop nutrition, Lucent Biosciences enables farmers to cultivate nutrient-dense crops without polluting groundwater, thereby supporting regenerative agriculture and reducing overall costs per hectare.

AdeptMind is a Toronto-based SaaS company that develops an AI-powered e-commerce product discovery and search platform. Founded in 2016, it uses deep learning and natural language processing to deliver personalized search results and smart filtering, helping online retailers reduce no-result searches. The platform collects data across all products to power recommendations without requiring third-party search tools, and it targets shopping center marketplaces and e-commerce product discovery.

FTEX is a Montreal-based developer of next-generation smart, connected drive systems for light electric vehicles. The company provides the electronics, software and applications that control vehicle motors, all connected in real time over cellular networks to FTEX's cloud platform. Its EVionics mobile operating system enables features such as location tracking, diagnostics, security, remote locking, collision detection, service and theft insurance. FTEX aims to accelerate adoption of personal electric vehicles by delivering smart motor controllers that enhance performance, range and user experience through novel technology and standards.

Iris Dynamics is a Canadian technology startup specializing in magnetic force controlled actuator motors. Its innovative process enhances human-machine interfaces, benefiting diverse markets such as aircraft controls, robotics, and industrial automation. The company also develops high-performance stabilization platforms and supports electromagnetic research at major Canadian universities.

Private AI Inc., founded in 2017 and headquartered in Toronto, Canada, specializes in developing privacy-preserving machine learning and natural language processing tools. The company focuses on enabling organizations to securely analyze large datasets that contain sensitive information without compromising user privacy. Its technology excels in identifying, redacting, and generating synthetic personally identifiable information (PII) across more than 50 entity types and supports over 47 languages with an accuracy exceeding 99.5%. Private AI's solutions are designed to integrate seamlessly with clients' existing infrastructures, ensuring that their data remains secure and never leaves their environment. Through these innovations, Private AI aims to enhance the capabilities of developers while maintaining the highest standards of data privacy.

Vodasafe Inc. develops AquaEye, a handheld scanning sonar device used by emergency responders, lifeguards, and recreational users for water-based search and rescue. The device uses sonar and artificial intelligence to detect submerged persons, provides distance and direction to victims, records rescue data, and can connect via Bluetooth to other devices. The company is based in Kelowna, Canada.

Summit Nanotech Corporation is a Calgary-based cleantech company developing direct lithium extraction technology for lithium producers, with modular systems designed for scalable deployment and a focus on sustainable, water-efficient operations. Founded in 2018, it collaborates with mining companies and lithium asset owners in Chile and Argentina to reduce environmental impact and lower costs compared with traditional methods.

Rithmik Solutions is a Montreal-based company that develops an AI-powered platform for predictive maintenance on mobile mining equipment. Its solution, including the Asset Health Analyzer, analyzes equipment health, detects deviations from a virtual model of a healthy asset, and provides insights to reduce maintenance needs and improve uptime. The platform tracks asset health to help optimize productivity and profitability in the mining sector. Founded in 2017, Rithmik Solutions serves mining operators by turning AI analytics into actionable maintenance decisions.

Founded in 2019 with headquarters in San Sebastian, Spain, Multiverse Computing develops quantum computing software tailored to solve complex real-world challenges. Its software leverages probabilistic technology for portfolio optimization, risk analysis, and market simulation, serving clients across industries such as finance, energy, manufacturing, and logistics.

BarrelWise Technologies specializes in developing advanced technical systems for the wine industry. Its flagship product, the FS1 System, enables wineries to perform routine free SO2 checks on-site, reducing analysis time from days to minutes while maintaining lab-level accuracy.

Path Therapeutics, Inc. is a biotechnology company based in Calgary, Canada, focused on developing a novel neurometabolic, phenotypic drug discovery platform. This innovative platform aims to enhance drug discovery by identifying new protein targets and measuring improvements in mitochondrial function. By utilizing phenotypic screening technology, Path Therapeutics evaluates repurposed libraries with well-characterized molecular targets, facilitating the reverse identification of druggable proteins. The company's approach is particularly beneficial for addressing central nervous system disorders, including epilepsy, autism, and age-related conditions. Founded in 2013, Path Therapeutics seeks to enable de novo drug discovery and uncover novel mechanisms of action in the neuroscience field, with a focus on rare and pediatric epilepsies.

BreatheSuite develops an inhaler attachment that connects to a smartphone via Bluetooth. It provides real-time feedback on inhalation technique and medication dosage for asthma and COPD patients, ensuring proper usage and symptom control.

PulseMedica is a medical device company based in Edmonton. It develops non-invasive, automated image-guided laser treatments for vitreoretinal diseases using 3D computer vision and femtosecond laser technology.

Founded in 2015, Arylla specializes in nanotechnology-based invisible ink for authenticating luxury goods. It offers a platform that enables luxury brands to apply its ink during production, allowing resellers to verify product authenticity using smartphones.

Mayday Labs Inc. is a Toronto-based company that specializes in designing and developing wellness and productivity software solutions. Founded in 2018, the company focuses on creating an AI-assisted scheduling tool that helps users organize and optimize their time effectively. This tool analyzes how time is allocated across various activities and offers calendar management features, including automatic travel time scheduling. By providing personalized assistance and recommendations for daily time management, Mayday Labs aims to enhance productivity and adapt to changing schedules, enabling users to manage their time more efficiently.

Founded in 2018, Brink Bionics specializes in developing advanced prosthetic technologies. Its flagship product is the Axo Hand, a six-degree-of-freedom myoelectric hand prosthesis designed for adults with below-elbow limb differences.

Open Ocean Robotics is a company that specializes in collecting ocean data using solar-powered autonomous boats. Founded in 2018 and based in Victoria, British Columbia, the company operates unmanned surface vehicles (USVs) equipped with sensors, cameras, and communication devices. These boats can gather real-time information from various locations across the ocean, providing valuable insights for environmental protection and sustainability. Their data collection capabilities are instrumental in monitoring ocean traffic, detecting illegal fishing activities, studying marine mammals, and understanding the effects of climate change. By offering a safe, efficient, and cost-effective alternative to traditional crewed vessels, Open Ocean Robotics contributes to the preservation of marine ecosystems and the promotion of responsible ocean management.

Covalent Research & Development Inc. is a technology company based in Vancouver, Canada, focused on enhancing transparency and accountability in the cryptocurrency sector. Established in 2018, Covalent develops a data analytics suite that addresses significant infrastructure challenges obstructing blockchain adoption. Its offerings include on-chain data and analytics for the Ethereum network, as well as APIs that provide visibility and transparency across various blockchain networks. The company aims to bridge centralized databases with decentralized blockchain technologies, thereby facilitating adoption among enterprises and consumers. Covalent supports several leading decentralized finance protocols and is actively building tools like SafeKeeep, which aims to improve data availability and record-keeping in the DeFi space. The company’s team comprises industry veterans with extensive experience in database and distributed systems, underscoring its commitment to driving innovation in blockchain technology.

Workwolf is a Toronto-based startup that develops software to streamline hiring by filtering applicants and verifying resumes. Its CEO, Erik Simins, previously founded MAGNUS HRS, a staffing firm that now serves over 150 enterprise customers. Workwolf’s platform uses blockchain and AI to provide up‑to‑date background verification, producing detailed reports for employers and allowing candidates to create verified profiles. The solution reduces manual effort, shortens time‑to‑hire, and lowers the risk of mis‑hiring. The company has earned three global innovation awards and is preparing for a $4.5 million seed financing round.

Founded in 2014, PhenoTips is a Canadian software company specializing in clinical genetics. It offers user-friendly solutions that integrate with existing electronic health records to streamline phenotyping and human phenotype ontology.

Revolve Surgical is a Toronto, Ontario-headquartered company developing a robotic surgery platform designed to enable robotic procedures across a broader range of operating rooms and to advance value-based care. The hybrid manual-robotic system eliminates teleoperation and seeks to reduce the size, cost, and training required by current robotic devices, expanding access to robotic surgery for patients. The technology targets abdominal surgeries performed outside traditional hospital settings, aiming to bring the benefits of surgical robotics to more care settings in the United States.

Epineuron Technologies, Inc. is a medical device company based in Hamilton, Canada, established in 2016. It specializes in developing innovative treatment strategies for peripheral nerve injuries through bioelectronic medicine. The company focuses on creating a suite of surgical solutions aimed at enhancing the repair and regeneration of peripheral nerves. Epineuron's flagship product is an electroceutical device that delivers targeted electrical stimulation to accelerate the natural healing processes of injured nerves. By leveraging this technology, Epineuron aims to set a new standard of care in the field of nerve injury treatment, aspiring to become a leader in bioelectronic nerve care.

Provision Analytics Inc., founded in 2018 and headquartered in Calgary, Canada, specializes in cloud-based solutions for food safety management. The company provides software designed for food processors and manufacturers, streamlining food safety processes by automating data input and recall procedures. This technology connects detailed process data with production outcomes, enabling the generation of analytics that help minimize food loss and improve quality control. By enhancing traceability and tracking throughout the supply chain, Provision Analytics supports the food industry in ensuring safety and compliance.

Menten AI, established in 2018 with headquarters in San Francisco and a satellite office in Toronto, is an early-stage biotech company specializing in drug discovery. It leverages machine learning and quantum computing to develop novel protein-based drugs and enzymes for pharmaceutical and chemical industries. Menten AI's core offering is a proprietary protein design algorithm tailored for current and near-term quantum computers, enabling efficient exploration of protein structures for therapeutic applications, such as oncology and neurodegeneration, and industrial enzyme development.

Evercloak is a Waterloo, Canada-based materials company that develops ultra-thin graphene and other 2D nanomaterial films for cleantech applications. It employs a low-cost manufacturing platform to produce continuous coatings and ultra-thin membranes, enabling energy-efficient technologies across oil and gas, nuclear, energy, mining and agriculture sectors. The company aims to reduce energy use and greenhouse gas emissions by cooling buildings without warming the planet, delivering solutions that improve indoor comfort and support sustainable building operations.

Measure Protocol Limited is a London-based company established in 2018, with additional offices in Silicon Valley, Toronto, and Chennai. It develops a blockchain-powered application that serves as a marketplace for personal data, addressing concerns related to fraud, privacy, transparency, and consumer engagement. The application enables users to earn compensation for completing surveys and to connect various personal data sources, including location, health, and purchase history from online accounts. By providing verified, first-party consumer behavior insights, Measure Protocol aims to overcome the accuracy and scalability challenges faced by modern digital advertising. Its deterministic panel offers high-fidelity behavioral insights, ensuring that brands target genuine high-intent consumers instead of relying on inferred data, thereby enhancing the effectiveness of marketing strategies.

Founded in 2019 and based in Halifax, Canada, Gibli Tech develops innovative aerodynamic sensors designed to enhance athletic performance. Their real-time sensor technology provides cyclists and triathletes with critical aerodynamic data, enabling them to optimize equipment choices, adjust riding positions, and improve overall efficiency.

Arma Biosciences develops a sensor platform for continuous monitoring of a wide range of physiological markers. The platform uses sensing tips compatible with saliva, blood, urine, sweat, and tears and can be rapidly developed to detect diverse health indications, including cardiac biomarkers such as BNP, CRP, and Cardiac Troponin, enabling individuals to access real-time information about their health status. The company is headquartered in Toronto, Ontario.

Ubenwa is a Montreal-based startup focused on advancing automated sound-based medical diagnostics through innovative artificial intelligence technology. The company has created a pioneering system for the rapid detection of neurological and respiratory conditions in infants, relying solely on the analysis of their cry sounds. This technology, developed in collaboration with Mila - the Québec AI Institute and the McGill University Health Center, enables healthcare providers to diagnose conditions such as birth asphyxia in a cost-effective manner. By utilizing machine learning to evaluate the amplitude and frequency patterns of infant cries, Ubenwa's solution aims to enhance primary healthcare, support clinical trials, and improve neurodevelopmental care for newborns. The team comprises award-winning scientists, engineers, and medical professionals dedicated to transforming infant healthcare through sound analysis.

Smart Access Inc., established in 2015 and based in Edmonton, Alberta, specializes in developing software solutions tailored for retail workforces. The company's primary product is a mobile performance support platform designed to expedite worker training and skill development using location-aware technology. This platform offers features such as onboarding, user management, content management, and operational intelligence, aiming to enhance workforce efficiency and competence by providing intuitive access to essential knowledge.

Founded in 2015, G2V Optics specializes in manufacturing LED solar simulators and commercial lighting automation products for scientific research, vertical farming, and industrial applications. Its product offerings include horticulture lighting systems designed to improve yield, quality, and operating costs.

InVivo AI is a Montreal-based company founded in 2017 that specializes in leveraging artificial intelligence to enhance pharmaceutical research and development, with a particular focus on preclinical toxicology. The company has developed advanced AI methods for molecular representation, structure and ligand-based de novo design, and multiparameter optimization, enabling the creation of novel chemistry to address complex biological challenges.

Aifred Health Inc. is a Montreal-based company that specializes in developing a deep-learning clinical decision support tool aimed at enhancing personalized medicine in psychiatry. Founded in 2017, Aifred Health addresses the challenges associated with the traditional trial-and-error approach to treatment selection for mental health, particularly in depression, which is a leading cause of medical impairment worldwide. The company's application software provides features such as treatment prediction, interpretability, and patient data tracking, enabling physicians to make informed decisions tailored to individual patients. By processing de-identified data, Aifred Health's AI model facilitates personalized therapeutic choices, thereby improving the likelihood of effective treatment outcomes for patients who often do not respond to initial interventions.

SucSeed is a socially-driven hydroponics company. They sell their grow tanks and accessories to households across Canada. Their at-home hydroponic systems are built by Choices For Youth, an organization that supports and employs youth facing barriers to work and housing.

Vouched specializes in AI-powered visual identity verification, enabling swift user onboarding for businesses across various sectors such as healthcare, finance, real estate, and retail. Its patent-pending technology can verify hundreds of ID types from numerous countries, having already identified hundreds of thousands of individuals worldwide.

Ratio.City is a Toronto-based developer of an online mapping and analysis platform for real estate development. The platform enables users to identify potential development locations and to model 3D building massing for low-, mid-, and high-rise scenarios while incorporating city planning regulations to inform land valuations. By generating a three-dimensional building simulation, it helps real estate professionals strategically identify sites that fit target markets and quickly assess land value. The company focuses on providing tools and data to evaluate development opportunities efficiently. Founded in 2017, Ratio.City serves the real estate industry.

Coloursmith Labs Inc. is an optical filtering technology company based in Halifax, Canada, founded in 2018. The company specializes in developing advanced optical filters for contact lenses, designed to enhance color saturation and assist individuals with color vision deficiencies. By focusing on innovative materials and the principles of light and optics, Coloursmith Labs aims to create products that offer protection from harmful light while addressing chromatic applications. Their mission centers on integrating science and creativity to expand the potential of human vision, thereby improving the quality of life for their users.

Coastal Genomics Inc., established in 2012 and based in Burnaby, Canada, specializes in research and development within the life sciences automation sector. The company is known for its ranger technology, which automates the gel-based size selection of biomolecules, a critical process in DNA analysis. By creating automated solutions tailored to sample preparation needs, Coastal Genomics addresses challenges in the medical diagnostics field, enhancing efficiency and precision in laboratory workflows.

Miru Smart Technologies, formerly known as Click Materials, is a Vancouver-based company specializing in advanced materials, particularly in the development of electrochromic windows for residential, commercial, and automotive applications. Founded as a university spin-off, Miru leverages over a decade of academic and industrial research to innovate traditional thin film production. This advanced fabrication process is designed to provide superior performance at lower manufacturing costs compared to existing technologies. By focusing on strategic partnerships, Miru aims to integrate its window technology into the growing trends of connected smart buildings and voice-activated smart homes, contributing to reduced greenhouse gas emissions and enhanced energy efficiency.

Founded in 2016, Merinio designs and develops cloud-based workforce automation software. Its platform streamlines labor forecasting, shift fulfillment, scheduling validation, compliance management, and communication to enhance operational efficiency, minimize costs, and improve employee satisfaction.

Imeka Solutions Inc., established in 2011 and based in Sherbrooke, Canada, specializes in medical image processing services. It provides advanced MRI-based techniques such as diffusion tensor imaging, tractography, and free water imaging to clients including neurologists, clinicians, and pharmaceutical researchers. Imeka's platform leverages deep learning algorithms and high-resolution MRI structures to quantify and understand brain connectivity, particularly white matter, aiding in neuroinflammation and demyelination research.

16 Bit Inc. is a Toronto-based company that develops medical image analysis systems, focusing on artificial intelligence software designed to enhance diagnostic capabilities for healthcare professionals. The company is working on a triaging algorithm specifically for breast cancer screening, as well as systems for neurological emergency detection and pediatric bone age assessment. By creating trusted AI software as a medical device, 16 Bit aims to improve the quality, efficiency, and accessibility of healthcare, ultimately assisting physicians and radiologists in interpreting medical images more effectively.

StratumAI Inc. is a Toronto-based company that specializes in developing artificial intelligence-driven software for the mining industry. Founded in 2018, StratumAI focuses on enhancing the efficiency and accuracy of drilling data collection and analysis. Its software employs deep learning techniques to predict optimal drilling locations and estimate the quantity of gold and other metals present in the subsurface. This innovative approach replaces traditional statistical interpolation methods, which can be costly and less precise. StratumAI's technology has also shown effectiveness in assessing base metals, such as copper. By streamlining the exploration process, the company aims to deliver significant economic value, with projections indicating that its solutions could generate substantial annual savings for mining operations.

LlamaZOO Interactive, based in Victoria, BC, Canada, specializes in transforming complex data into immersive three-dimensional visualizations. The company's platform integrates real-time 3D technology, commonly found in the gaming industry, to help organizations visualize their data within its real-world context. By enabling users to view and interact with data as 3D models, LlamaZOO facilitates a deeper understanding of information and enhances decision-making processes. Its use of augmented and virtual reality not only provides centralized oversight of real-time data but also creates engaging communication tools that allow stakeholders to derive meaningful insights and take decisive action.

Nanogrande is a Montreal-based developer of additive manufacturing systems that specializes in high-definition manufacturing for the 4.0 industrial revolution. The company has pioneered a patented process that enables the production of particle layers as thin as one nanometre, resulting in the world's first nanoscale 3D printer. This innovative technology allows for the creation of ultra-high-resolution and precision parts using a diverse range of materials, including metals, polymers, and ceramics. By offering unparalleled design freedom and intricate detail, Nanogrande's solutions cater to industries needing complex objects while potentially reducing production costs by up to 50%. The company's advancements position it to capture significant opportunities in the rapidly growing markets of metal injection moulding, precision metal casting, and components for microelectromechanical systems. Through its unique approach, Nanogrande is effectively bridging the fields of nanotechnology and additive manufacturing.

CapIntel Inc. is a financial technology company based in Toronto, Canada, founded in 2017. It develops an online platform designed to enhance financial advisory services, utilized by over 12,000 financial advisors and asset management sales teams across North America. The platform integrates investment analytics with collaborative tools, facilitating better communication between asset managers and advisors, and improving the overall client experience. By enabling financial advisors to build client portfolios, compare fund performance, and create easily comprehensible proposals, CapIntel enhances advisors' confidence in communicating investment options to their clients. The company's solutions aim to increase sales for both advisors and asset managers, positioning CapIntel as a leading sales platform in the financial advisory sector.

CleanO2 Carbon Capture Technologies develops devices to reduce greenhouse gas emissions from heating, ventilation and air conditioning systems. Founded in 2013 and based in Calgary, Alberta, the company has produced residential and commercial carbon capture devices, including CARBiNX, aimed at recovering heat and capturing carbon for use as a by-product. The technology converts waste carbon into chemicals used in the soap and detergent industry, enabling businesses to lower emissions and energy demand while pursuing global deployment.

QReserve is a platform that helps organizations manage, promote, and share resources such as meeting rooms, equipment, and facilities. It provides analytics tools to track utilization rates, revenues, capacity, and performance. The platform enables users to discover, access, and book these resources, serving notable clients like SickKids, UBC Okanagan, and McMaster University.

BeatDapp is a music technology company that provides streaming fraud detection and data integrity solutions for the music industry. The platform authenticates and validates media streamed in real time to reduce discrepancies between digital service providers and rights holders, helping labels, artists, and distributors ensure fair compensation and lower audit costs. With offices in Vancouver, Los Angeles, and Toronto, BeatDapp serves streaming services, labels, collection societies, creator tools, and distributors by delivering accurate streaming data and insights to combat fraud and improve royalty reporting.

Spiderwort is an innovative company based in Ottawa, Ontario, founded in 2015, focused on developing biomaterials for regenerative medicine. The company specializes in creating cellulose-based biomaterials that serve as living scaffolds, which can be utilized for various medical applications, including spinal cord injury repair and soft tissue regeneration. Spiderwort's products encompass a range of biological and synthetic polymers available in multiple forms, such as powders, gels, membranes, and pastes. Currently in the pre-clinical stage, their novel biomaterials have shown promising results in terms of biocompatibility and the ability to induce angiogenesis, which is the generation of blood vessels within the scaffold. This approach aims to advance the repair and regeneration of tissues within the human body, providing new solutions for challenging medical conditions.

Leap Biosystems is a Canadian company that specializes in developing innovative next-generation medical technologies and astronaut medical training platforms. Their mission is to support upcoming human space exploration initiatives by providing advanced healthcare solutions designed for remote environments. The company combines clinical medicine with space exploration technologies, enabling clients to access remote medical procedure guidance technology.

Forcen develops and manufactures force-sensing film for various industries, including surgical robotics, industrial robotics, and aerospace. Its film can be integrated into parts or assemblies of devices in these sectors, providing real-time force feedback. Founded in 2015, the company is headquartered in Toronto, Canada.

SiteVue is a real-time site management platform for the construction industry that enables project managers to monitor progress by securely storing data in the cloud and making it accessible to the project team. The platform offers automated photo mapping, deficiency tracking, and customizable reports, along with GPS-based mapping of photos to drawing locations and instant sharing of progress updates. All data is stored securely in the cloud to support up-to-date information across the team, helping reduce rework, improve productivity, and support safer, more efficient site operations. Founded in 2016 and based in Kitchener, Canada.

Doorr Inc. is a Toronto-based company founded in 2018 that specializes in developing application software for the mortgage industry. The company offers a digital mortgage platform designed to streamline the mortgage process for brokers, agents, and financial institutions. This platform facilitates collaboration between brokers and their clients, providing tools for managing pre-approvals, refinances, and purchases in a centralized location. By digitizing the entire mortgage experience—from document management to deal funding—Doorr enhances efficiency and improves visibility throughout the application and approval process. Its solutions also include data visualization and customizable websites, allowing agents to better serve their clients and navigate the complexities of the mortgage market.

Founded in Toronto in 2018, Grain Discovery operates an online marketplace that leverages blockchain technology to facilitate efficient, transparent, and secure transactions between farmers and buyers. Its platform offers tools for instant bids, contract finalization, ERP integration, CRM consolidation, and traceability solutions, enabling agricultural supply chain verticals to manage operations more efficiently.

Naegis Pharmaceuticals Inc. is a Canadian biopharmaceutical company dedicated to developing innovative small molecules aimed at treating serious inflammatory diseases, particularly those affecting the eye. The company focuses on chronic inflammatory conditions that significantly impact the quality and quantity of life, especially in an aging population. Naegis seeks to create safer and more effective therapeutic options by designing compounds that target the underlying inflammatory processes in these diseases. Their research initially concentrates on serious eye conditions that cause damage to the back of the eye, with a specific program aimed at blocking the synthesis of pro-inflammatory mediators. By delivering these treatments via eye drops directly to the retina, Naegis aims to address leading causes of blindness and improve patient outcomes.

Lunie is a non-custodial cryptocurrency platform based in Toronto, Ontario, designed for both mobile and web use. The company focuses on staking and governance for proof-of-stake blockchains, providing developers with support across various networks, including Cosmos, Polkadot, Kusama, and Terra. Lunie's mission is to facilitate the growth and management of these blockchain ecosystems, emphasizing user control and security in cryptocurrency transactions.

Miru Smart Technologies, formerly known as Click Materials, is a Vancouver-based company specializing in advanced materials, particularly in the development of electrochromic windows for residential, commercial, and automotive applications. Founded as a university spin-off, Miru leverages over a decade of academic and industrial research to innovate traditional thin film production. This advanced fabrication process is designed to provide superior performance at lower manufacturing costs compared to existing technologies. By focusing on strategic partnerships, Miru aims to integrate its window technology into the growing trends of connected smart buildings and voice-activated smart homes, contributing to reduced greenhouse gas emissions and enhanced energy efficiency.

QuantumSense is an artificial intelligence company based in Canada that specializes in advanced semantic search technology. As a graduate of the Creative Destruction Lab's quantum machine learning track, the company has developed a platform that transcends traditional keyword searches by analyzing the meaning and structure of sentences. This innovative approach allows for efficient comparisons and significantly enhances the accuracy and speed of searches for ideas or text passages within documents and archives. QuantumSense's technology also includes capabilities for question answering, named entity recognition, and sentiment analysis, making it valuable for various industries. In finance, it can analyze unstructured data to improve predictive accuracy, while in the insurance sector, it streamlines and accelerates the claims process, thus enhancing operational efficiencies for insurers.

Contxtful Technologies is a Montreal-based analytics company that develops an AI-powered platform to measure audience context and intent through privacy-preserving sensor data from mobile devices while prioritizing user privacy. The system uses sensor signals to assess attention, viewability, and engagement, providing real-time insights to optimize digital advertising and marketing campaigns. It offers audience targeting, segmentation, and programmatic optimization, delivering measurement of ad effectiveness and performance scores for online and video content. The technology is GDPR-compliant and does not require explicit user permission, avoiding reliance on GPS, cameras, or microphones. It serves diverse industries, including Adtech, Martech, finance-related sectors, streaming, and game engines, helping publishers and advertisers improve ad monetization and campaign outcomes.

DarwinAI Corp. is a Canadian company that specializes in artificial intelligence technology, particularly in the development of deep neural networks for enterprise applications. Founded in 2017 and based in Waterloo, the company offers GenSynth, a software platform designed for developers and data scientists to streamline the deep learning development process. GenSynth employs generative synthesis technology, allowing for the automatic creation of optimized, explainable AI models that meet specific performance criteria while ensuring transparency throughout the development stages. Additionally, DarwinAI has developed an AI-powered visual quality inspection system aimed at enhancing the PCBA manufacturing lifecycle. This system leverages specialized optics and advanced algorithms to detect defects in products, improving quality and consistency while reducing costs for manufacturers.

INDUS.AI is a construction intelligence platform that provides real-time visibility into construction sites for real estate investors, owners, developers, and general contractors. The platform uses live video from secure cameras to identify inefficiencies, monitor productivity, and surface risks, enabling project teams to optimize labor, equipment, and materials, reconcile over-billed charges, and adjust schedules. It aims to improve safety, efficiency, and transparency on projects. Founded in 2017, INDUS.AI has offices in San Francisco and Toronto and serves clients in the United States, Canada, Hong Kong, and Brazil.

Ideon Technologies develops advanced borehole detectors and a discovery platform that integrates proprietary sensors, imaging systems, inversion technologies, and AI for detecting subsurface muons. This enables x-ray-like imaging and generation of 3D density maps, serving industries such as mining, oil & gas, infrastructure, and security.

Kognitiv Spark Inc. is a Canadian company specializing in mixed reality software solutions designed to enhance the capabilities of industrial workers. Founded in 2016 and headquartered in Fredericton, the company’s flagship product, RemoteSpark, is a cloud-based application that enables remote technicians to connect with experts through devices like tablets, phones, laptops, and HoloLens headsets. This platform facilitates real-time guidance by allowing experts to see what technicians see and to provide holographic instructions and resources, significantly improving task execution and training. Kognitiv Spark's offerings are particularly beneficial in sectors such as aerospace, defense, and security, where they help reduce equipment downtime, streamline knowledge transfer, and minimize the necessity for expert travel. With a focus on industrial-grade security and low-bandwidth operation, RemoteSpark is recognized for its reliability and effectiveness in complex operational environments.

Founded in Ottawa, Canada in 2015, eMurmur is a digital health company specializing in the detection, analysis, and classification of heart murmurs using machine learning. Its platform enables remote recording and analysis of auscultation sounds, facilitating screening, monitoring, diagnosis, and consultation for heart health.

Bridge7 is a Canadian company founded in 2017 that specializes in developing AI-powered consultation software aimed at improving cancer care delivery. The software employs advanced machine learning algorithms to analyze data from thousands of patients, providing clinical teams with decision-making metrics to enhance the quality of care. This innovative approach enables healthcare providers to gain valuable insights and consultations regarding cancer treatment options before patients initiate their treatment courses, ultimately leading to increased clinical efficiency and improved quality in cancer care delivery. Headquartered in Ontario, Bridge7 is committed to ensuring that patients receive the most effective and timely care from specialized cancer treatment centers.

Brisk Synergies Inc. is a technology company specializing in the design and development of solutions for urban planners and engineers focused on traffic movement analysis. Founded in 2013 and headquartered in Waterloo, Canada, with an additional office in Montréal, the company offers advanced software platforms, including BriskLUMINA and BriskVANTAGE. BriskLUMINA tracks and classifies individual road users while detecting near-misses and potentially dangerous interactions, whereas BriskVANTAGE employs artificial intelligence and computer vision to monitor real-time video data, enabling the identification of collision risks. These tools provide transportation engineers with critical insights into road safety issues, allowing for proactive measures to enhance traffic infrastructure and urban mobility. As of January 2020, Brisk Synergies operates as a subsidiary of Transoft Solutions, Inc.

Delphia Inc. is a Toronto-based company, incorporated in 1993, that specializes in developing artificially intelligent surveys designed to assist individuals in making informed decisions regarding careers, education, finances, and health. The company emphasizes the importance of data in fostering capital formation and economic empowerment. Delphia creates products that encourage the sharing of proprietary data, aiming to provide users with a competitive advantage in financial markets. By actively managing personal data, Delphia seeks to unlock innovative opportunities for wealth creation for both individual and institutional investors.

Founded in 2016, LabsCubed specializes in manufacturing automated material testing systems. These systems are designed to efficiently load tensile samples and plastic materials for numerical simulation, aiding companies in creating innovative materials.

GenXys Health Care Systems Inc., based in Kelowna, Canada, specializes in precision prescribing software and pharmacogenetic solutions designed to prevent adverse drug reactions. The company has developed a platform that integrates medication interactions, genetic data, and health information, allowing clinicians to make informed prescribing decisions with enhanced accuracy. This platform is utilized by molecular lab companies for the clinical translation and interpretation of pharmacogenetic tests, delivering real-time, clinically relevant information at any point of care. GenXys's software addresses the significant health challenge of adverse drug reactions, which are among the leading causes of death globally. The company aims to revolutionize prescription practices worldwide, contributing to the advancement of precision medicine for all patients.

Zennea Technologies is a medical device company based in Surrey, Canada, specializing in the development of therapeutic wearables aimed at reducing snoring and improving overall health through enhanced sleep quality. The company's flagship product, ZENS, is a comfortable and discreet sleep wearable that targets the root cause of snoring, thereby assisting individuals with chronic snoring and mild obstructive sleep apnea. Zennea conducts clinical trials to validate the efficacy of its device, which not only helps reduce snoring but also tracks sleep quality, providing valuable insights for users to make informed decisions about their health and sleep habits.

TritonWear is a Canadian wearable technology company based in Kitchener that develops performance wearables and companion software to help coaches and athletes track performance in real time. Its waterproof wearable, paired with mobile and web applications, delivers real-time and post-workout metrics, AI-powered analytics, video motion analysis, and cloud storage, enabling swim teams, coaches, and athletes to monitor progress, identify improvement areas, and make data-driven training decisions.

Pancella Inc. is a biotechnology company based in Mississauga, Canada, founded in 2015. The company specializes in developing innovative cell therapies aimed at treating degenerative and malignant diseases. Its flagship product, the FailSafe cell therapy system, incorporates advanced safety mechanisms that allow for precise control over cell proliferation. By linking a drug-inducible suicide gene with a gene essential for cell division, Pancella's technology enables healthcare professionals to eliminate potentially malignant cells at will, either before or after transplantation. This approach enhances the safety and efficacy of cell-based therapies, providing critical support for regulators, clinicians, and patients in their treatment decisions.

Notch Therapeutics is a Toronto-based company developing immune cell therapies using induced pluripotent stem cell technology to create gene-edited allogeneic T cells. Its platform enables precise control of Notch signaling during T-cell development, enabling scalable manufacture of a uniform supply of therapeutic T cells for cancer indications such as non-Hodgkin lymphoma, leukemia, and multiple myeloma. The approach aims to overcome bottlenecks in cell therapy development by integrating advanced product design with commercially compatible processes, supporting a next-generation pipeline of cell therapies.

AuroraQ is a quantum computing startup based in Toronto, Canada, founded in 2017, that develops standardized and modular quantum components designed to integrate with a range of quantum processor technologies and scale with customer needs. The company sells its modular components to existing quantum computing companies as well as academic and government customers, enabling easier access to quantum capabilities and broader market participation. In addition, AuroraQ offers engineering services for superconducting quantum processors, including designing and running quantum circuits, deriving the equations that describe time evolution, analyzing parasitic dissipation of quantum information, and simulating circuit behavior under varying environmental conditions, helping customers advance quantum computing development.

Plum.io, Inc. is a Canadian software company that has developed a recruitment platform leveraging data-driven assessments to match job candidates with organizational needs. Established in 2012 and formerly known as Cream.HR, the company aims to enhance talent acquisition and management processes through its software as a service (SaaS) offerings. Plum's platform provides tools for workforce re-organization, planning, succession, and employee development, enabling organizations to quantify job fit and improve hiring quality. By focusing on objective data, Plum facilitates personalized career insights and helps create high-performing teams. The company has received recognition in the HR industry, including awards for its innovative technology.

ProteinQure is a biotechnology company focused on designing novel exotic peptides with broad therapeutic applications. It leverages quantum computing, atomic-level simulations, reinforcement learning, and artificial intelligence to engineer dynamic peptide therapeutics and to design protein structures with efficiency. The company provides structure determination, protein design, and property determination to enable drug discovery and design. Founded in 2017, ProteinQure is based in Toronto, Canada.

Untether AI Corporation, established in 2017 and headquartered in Toronto, Canada, specializes in the development of advanced neural net-based inference processors and chips. These processors are designed to enhance the capabilities of various devices, such as augmented reality headsets and wearables, enabling them to perform complex tasks like machine vision and speech recognition. The company focuses on a unique architecture that minimizes energy consumption while maximizing inference performance, addressing the challenges posed by strict energy budgets in modern devices. By employing a near-memory design, Untether AI’s technology reduces the distance data must travel during processing, thereby improving efficiency and lowering resource requirements. This innovative approach positions Untether AI as a leader in the evolving landscape of artificial intelligence applications, where effective inference is critical for advancing device intelligence.

Variense is a startup based in Montreal that offers Industrial IoT sensing solutions.

Creatus Biosciences Inc. is a biotechnology company based in West Vancouver, Canada, focused on the production of genetically engineered microorganisms that convert xylose sugars into valuable chemical compounds. Founded in 2014, the company employs proprietary mixed-sugar biorefinery technology and advanced genetic engineering techniques to develop high-value, low-volume chemicals from second-generation feedstocks. This innovative approach allows for versatile applications of xylose utilization across various industries, including biofuels and food additives. By leveraging metabolic engineering and synthetic biology, Creatus Biosciences aims to provide sustainable and efficient chemical solutions, contributing to the growth of green chemistry in industrial markets.

Founded in 2016, LabsCubed specializes in manufacturing automated material testing systems. These systems are designed to efficiently load tensile samples and plastic materials for numerical simulation, aiding companies in creating innovative materials.

Borealis Wind is a Canadian company based in Kitchener, Ontario, founded in 2016. It specializes in developing an innovative internal blade heating retrofit for wind turbines, aimed at enhancing their performance in cold climates. This patented device effectively prevents and removes ice buildup on turbine blades, which can lead to significant losses in power generation and revenue for wind farms during winter months. By providing a low-maintenance and easily installable de-icing solution, Borealis Wind is contributing to increased efficiency and reliability in the wind energy sector, addressing critical challenges faced by renewable energy sources in harsh weather conditions.

Dooly Research Ltd. is a Vancouver-based company that specializes in developing artificial intelligence-driven software designed to enhance the efficiency of sales teams. Founded in 2015, Dooly's platform automates the customer relationship management process by monitoring and sharing digital notes, fields, and tasks from meetings and customer interactions. This software facilitates the seamless transfer of information between team members and systems, thereby addressing the challenges of note-taking and information sharing. By organizing workflow systems in real-time, Dooly's platform enables businesses to minimize administrative tasks, allowing sales teams to concentrate on core activities essential for closing deals.

Orpyx Medical Technologies Inc. is a Calgary-based company that develops innovative mobility sensor devices aimed at supporting diabetic patients in maintaining their mobility. Founded in 2010, the company offers several key products, including the Orpyx SI sensory insoles, which are designed to manage and prevent diabetic foot ulcers and limb loss by capturing real-time data related to pressure, temperature, and movement. Additionally, Orpyx provides Kinetyx, a mobile in-shoe pressure management system that collects clinical plantar pressure data for various applications, including sports medicine and therapeutic use. Another notable product is SurroGait Rx, which assists multiple sclerosis patients in improving their mobility and balance. Orpyx Medical Technologies emphasizes the importance of prevention in healthcare and collaborates with global stakeholders to promote sustainable health solutions.

Founded in 2015, Cerebri AI specializes in real-time data engineering and artificial intelligence modeling. Its platform, Answers-as-a-Service, processes complex datasets to provide near-instant insights for decision-making, focusing on customer experience (CX) and traveler experience (TX). The company is headquartered in Austin, Texas.

Innovative Protein Technologies is a biotechnology company focused on creating environmentally-friendly products derived from natural protein molecules for agricultural and home gardening applications. Founded by recent graduates from the University of Guelph and the University of Waterloo, the company aims to harness nature's protective strategies to develop effective solutions for crop protection. Its flagship product, Frost Armour, is a spray-on solution designed to safeguard valuable crops from frost damage during the spring growing season. In addition to this primary offering, Innovative Protein Technologies provides services related to expression optimization, stability testing, functional engineering, protein production, protein modification, and plasmid constructs, helping users utilize bio-based technologies effectively.

Shakepay Inc. is a Montreal-based technology company that specializes in financial applications aimed at helping users build wealth through cryptocurrency. Founded in 2015, Shakepay offers a platform that allows Canadians to buy and sell Bitcoin, as well as a peer-to-peer mobile wallet for secure transactions. The company's services include a VISA debit card that enables users to load and spend Bitcoin for various purposes, including point of sale transactions, ATM withdrawals, and online purchases. By providing these innovative financial tools, Shakepay aims to facilitate the use of digital currencies in everyday transactions.

Founded in 2014, Brizi develops remote-control augmented reality camera systems that automate and monetize fan content. It serves real-time sharing, social sharing, brand messaging, and end-to-end control applications for indoor and outdoor venues globally.

CryptoNumerics Inc. is an enterprise software company based in Toronto, Canada, founded in 2017. The company specializes in solutions that facilitate data privacy and security in compliance with regulations such as HIPAA and GDPR. Its flagship products include CN-Fuse, which identifies key intersections across decentralized datasets; CN-Shroud, which balances re-identification risk and data quality through differential privacy and anonymization; and CN-Insight, which enables the training of machine learning models to predict adverse drug reactions. By allowing organizations to create privacy-protected datasets and build statistical models while safeguarding intellectual property, CryptoNumerics empowers data owners to leverage machine learning in a distributed manner, enhancing insights and operational efficiency while minimizing costs and risks. As of July 2020, CryptoNumerics operates as a subsidiary of Snowflake Computing Inc.

NanoQuan Inc. is a Canadian company based in Kitchener that specializes in the development and manufacturing of advanced nanocomposite materials. The firm focuses on creating innovative materials with exceptional electrical, mechanical, optical, and thermal properties, catering to various industries, including electronics, automotive, and aerospace. Utilizing a proprietary dispersion-mixing technology, NanoQuan effectively incorporates nano-fillers into a diverse range of host materials, allowing for customized solutions to meet specific industry requirements at competitive prices.

Wondereur Inc. is a digital art platform based in Toronto, Canada, founded in 2012. The company offers the Wondereur application for iPad and iPhone, which allows contemporary artists to share personal narratives and insights about their creative processes. Additionally, the platform features photojournalists who document artists' daily lives with visually striking imagery from studios and urban environments. Wondereur also aids curators in identifying emerging talent and acquiring art at favorable prices. The platform provides real-time intelligence on the art market, analyzing various factors that influence an artist's long-term market value, including endorsements from galleries, publications, and prevailing art movements. This analysis results in intelligent indices that suggest price ranges and projected growth rates for contemporary artworks, serving customers across Europe, Asia, the United States, and Canada.

FleetOps is a Toronto-based freight technology company that operates a freight marketplace and a carrier-focused platform to connect brokers, shippers, and trucking capacity. The company automates the allocation of loads to drivers by analyzing telematics data from providers to determine truck locations, routes, idle time, available driving hours, and driver behavior, and it uses AI to match loads with suitable drivers. The platform also delivers tailored analytics and KPIs for carrier trucking operations, helping to optimize dispatch and execution.

Founded in 2017, Phenomic AI is a Toronto-based company that develops artificial intelligence-driven drug discovery platforms. Its technology analyzes phenotypes in complex disease models like high-content co-culture and 3D assays, enabling pharmaceutical companies to discover drugs more efficiently.

Saccade Analytics Inc. is a Montreal-based company that specializes in developing clinical tools for analyzing data from patients' eye and head movements during simple tasks to assess brain function. Founded in 2016 by Dr. Mimi Galiana, a pioneer in the field of eye and head movement analysis, the company aims to enhance neurological care by translating advanced research into practical applications. Its flagship product, InSight, is designed for clinicians and therapists to diagnose and monitor conditions such as concussions, vestibular disorders, and other neurological issues. By harnessing decades of research, Saccade Analytics strives to provide accessible diagnostic tools that improve patient outcomes.

Routific, Inc. is a Vancouver-based company that specializes in route optimization solutions for delivery businesses. Its platform automates and enhances vehicle routing and scheduling operations, serving small and medium-sized enterprises both in Canada and internationally. Inspired by the foraging behaviors of honey bees, Routific's technology helps local delivery businesses efficiently plan routes, resulting in significant reductions in time and fuel consumption, as well as lowering carbon emissions by 20-40%. The software includes features such as intelligent route optimization, dispatch and live tracking, and delivery notifications, enabling companies to reduce delivery costs, improve driver efficiency, and enhance customer satisfaction.

DarwinAI Corp. is a Canadian company that specializes in artificial intelligence technology, particularly in the development of deep neural networks for enterprise applications. Founded in 2017 and based in Waterloo, the company offers GenSynth, a software platform designed for developers and data scientists to streamline the deep learning development process. GenSynth employs generative synthesis technology, allowing for the automatic creation of optimized, explainable AI models that meet specific performance criteria while ensuring transparency throughout the development stages. Additionally, DarwinAI has developed an AI-powered visual quality inspection system aimed at enhancing the PCBA manufacturing lifecycle. This system leverages specialized optics and advanced algorithms to detect defects in products, improving quality and consistency while reducing costs for manufacturers.

Careteam Technologies develops a digital health platform that facilitates collaboration among patients, families, and healthcare providers. The platform offers a virtual care plan, dynamic event lists, and secure messaging, enabling coordinated care across different settings.