Missouri Technology Corporation

Backstitch Inc. is a Kansas City-based company founded in 2012 that specializes in a platform for personalized employee communications. The platform serves business communicators by enabling them to create tailored communications for their teams, providing features such as push notifications, internal content, and industry news. Additionally, Backstitch's platform helps users analyze trends and behaviors, identify departmental allies, and measure the return on investment of their communications and engagement efforts. The company also develops an application that integrates a curated media monitoring platform, further enhancing its offerings for HR and internal communications teams.

Amptify is a leading provider of hearing healthcare services, leveraging a technology platform that connects users through mobile devices, the internet, video, and phone. Founded by a distinguished team of aural rehabilitation researchers at the Washington University in St. Louis, Amptify offers a comprehensive, evidence-based program designed for individuals with hearing loss. Its proprietary digital toolkit enhances communication abilities and supports the social, psychological, and physical well-being of patients. This innovative approach empowers hearing healthcare specialists to deliver personalized rehabilitation, making Amptify a significant player in the global hearing healthcare market.

iSite Media, LLC is a St. Louis-based company specializing in advertising and marketing services through innovative digital display technology. Established in 2015 and formerly known as Sitting Duck Advertising, the company focuses on delivering impactful brand promotions via a digital display network situated in restrooms. This unique positioning enables iSite Media to effectively engage consumers in a private setting, enhancing message recall and relevance. By leveraging location flexibility, the company bridges the gap between content and consumer, ensuring that advertising reaches the appropriate audience in a compelling manner. Since its inception, iSite Media has prioritized high-level engagement, recognizing the importance of targeting the right viewers for successful media campaigns. In 2017, it rebranded to underscore its commitment to modern advertising solutions.

Digital Sandbox KC is a Kansas City, Missouri-based venture studio that supports early-stage information technology ventures by providing proof-of-concept resources, access to technology, business and market experts, and funding for market validation, prototyping and beta testing.

Lindenwood University is a school in Saint Charles. Whether you are a busy working adult, recent high school graduate, or international student looking to study in the US, Lindenwood University (LU) might have what you are searching for in your pursuit of higher education. LU is a private, four-year institution that is founded on Judeo-Christian standards. It has undergraduate and graduate degrees on campus in an array of programs, including Biology, Computer/Graphic Arts, Fire and Paramedic Science, and Retail Merchandising. For those who are seeking a degree while working a job and need coursework to fit in with their busy schedule, LU provides courses in the evenings and online for added convenience. Financial aid is available to those who meet the criteria. Applications for financial assistance and admissions to LU can be done online or in person during a site visit. Beyond academics, the university offers students enriching experiences through athletic programs, clubs and organizations, leadership opportunities, and Greek life. It even built a recreational facility (Evans Commons) where students can hang out, watch movies, socialize, and meet new friends. If you like the idea of going to a larger school with a historic campus, extensive liberal arts curriculum, and full student life, consider Lindenwood University.

The eFactory is a business resource center located in southwest Missouri, specifically designed to support entrepreneurs and startups. It offers a 12-week intensive accelerator program aimed at jumpstarting emerging companies. Participants benefit from financial support, dedicated office space, and personalized mentoring, as well as business consulting services. The eFactory also facilitates introductions to potential follow-on funding sources and provides access to a recreation center, enhancing the networking opportunities available to its members. Through these resources, the eFactory fosters a collaborative environment that aims to promote innovation and growth within the local entrepreneurial ecosystem.

Launch KC is to attract and retain high-growth tech startups to Downtown Kansas City, Missouri. Meet your new colleagues and have the space you need. They’ll match your firm to seasoned business leaders to give you resources. Expand your business affordably. Their Data Center gives you better computing power, hosting, and data storage. Access higher bandwidth and work where you want, when you want with the freedom of their downtown wireless district. Grow your business. Take advantage of their tailored development incentives for your IT company. Test your ideas with state of the art equipment. Meet mentors and professionals who will develop your business. Partner with KCMO to develop or test an innovative solution for the City.

Arch Grants is a nonprofit organization established in 2011 and based in St. Louis, Missouri, dedicated to fostering economic development and community revitalization. It offers $50,000 equity-free grants and pro bono support services to entrepreneurs who establish their early-stage businesses in the St. Louis area. Through its highly competitive Global Startup Competition, Arch Grants aims to attract and retain innovative entrepreneurs, thereby inspiring future employers and civic leaders. The competition operates year-round, with grants awarded biannually in spring and fall. Arch Grants focuses on funding scalable business models across various industries, targeting innovative technologies, products, and services that have the potential for national or international impact.

Plastomics is a biotechnology company focused on chloroplast genetic engineering to enhance crop yields and nutritional quality. Its technology platform enables precise insertion of beneficial traits into chloroplasts, reducing cross-pollination and shortening breeding timelines. The company employs gene stacking and rapid breeding approaches to develop biotech crops with a broader set of traits, addressing industry challenges in seed development. Plastomics' approach is applicable across multiple crops and trait areas, supporting commercial trait expression while aiming to lower production costs. Founded in 2016 and headquartered in Saint Louis, Missouri.

CoverCress Inc. specializes in developing and commercializing field pennycress as a sustainable oilseed crop for industrial oils and livestock feed. Founded in 2013, the company is headquartered in Saint Louis, Missouri.

Digital Sandbox KC is a Kansas City, Missouri-based venture studio that supports early-stage information technology ventures by providing proof-of-concept resources, access to technology, business and market experts, and funding for market validation, prototyping and beta testing.

PatientsVoices, LLC is a healthcare technology company based in Parkville, Missouri, founded in 2013. The company operates a platform that utilizes data analytics to transform patient feedback—derived from surveys, social media, and complaints—into actionable insights for hospitals. By employing experts in computing and linguistics, PatientsVoices has developed a system that automatically categorizes feedback into improvement priorities from the patient's perspective. This platform not only helps hospital administrators understand how to enhance patient satisfaction but also aims to increase Medicare reimbursements by summarizing patient insights into a user-friendly format. Currently, the platform is being tested in various hospitals, demonstrating its potential to significantly improve patient care experiences.

Canopy Biosciences, founded in 2016 and headquartered in St. Louis, Missouri, is a biotechnology company specializing in research tools for genetic engineering, molecular biology, and personalized medicine. The company offers a comprehensive range of products and services designed to facilitate gene editing, gene expression analysis, and bioprocessing. One of its key technologies, TUNR, targets translation elongation by inserting polyA tracks into specific coding regions of the genome, effectively reducing mRNA levels and suppressing protein expression. This innovative approach supports biomedical researchers at universities, research institutions, and within the biotechnology and pharmaceutical sectors, accelerating scientific discovery and enhancing the field of genetic engineering. Canopy Biosciences operates as a subsidiary of Bruker Corporation.

Geneoscopy develops non-invasive diagnostics using stool-derived eukaryotic RNA to prevent, detect, and guide treatment for gastrointestinal diseases. Its platform technology enables early-stage detection of colorectal cancer neoplasms and improves screening compliance.

Lean Media, Inc. is a digital advertising company specializing in cookieless audience targeting services tailored for agribusiness and rural community advertisers. Founded in 2014 and based in Chesterfield, Missouri, the company employs advanced geo-targeting technology to connect with consumers at an individual level by analyzing IP addresses in conjunction with consumer databases. Lean Media's platform enables advertisers to customize campaigns based on specific workplaces, demographics, psychographics, and behavioral insights, allowing for more effective engagement and reduced advertising waste. The company focuses on delivering confidence to advertisers by enhancing their ability to reach target consumers through programmatic online display advertising.

Aptimmune is a biotechnology company headquartered in St. Louis, Missouri, established in 2010. It specializes in the development of mucosal vaccines aimed at preventing viral diseases in swine, specifically targeting the Porcine Reproductive and Respiratory Syndrome virus (PRRSV) and influenza A virus. By employing innovative technologies, including a proprietary pig alveolar macrophage cell line known as ZMAC, Aptimmune creates effective nasal delivery vaccines that provide lasting immune responses and enhance disease protection for animal breeders.

Keybot, Inc. is a company that designs and manufactures rental access robots, automating entry for rental properties through an innovative integration of hardware and software. Founded in 2018 and headquartered in St. Peters, Missouri, with additional locations in Kansas City and London, the company provides solutions for rental owners and property managers. Keybot's product facilitates self-showings and allows renters and maintenance personnel to access properties securely. The system employs digital keys that enable property managers to share access with verified third parties, manage locks remotely, and maintain access logs, thereby enhancing security and efficiency in property management. Keybot also operates a production office in Taipei City, Taiwan.

Tallyfy, Inc. is a company that develops online business process improvement and workflow management software, founded in 2014 and headquartered in St. Louis, Missouri, with an additional office in San Francisco, California. Its cloud-based platform focuses on automating and optimizing recurring workflows, allowing organizations, from Fortune 500 companies to small startups, to track processes in real-time, thereby reducing manual updates and enhancing efficiency. Tallyfy's software specializes in areas such as client onboarding, customer success, and compliance, enabling businesses to minimize human errors and streamline operations. Users can create templates, automate processes with conditional rules, and continuously improve workflows through feedback and metrics, fostering a culture of operational excellence.

Vector Legal Method is a software company based in Kansas City, Missouri, specializing in litigation management solutions. The company offers a cloud-based Software-as-a-Service platform designed specifically for corporate legal departments and law firms. This platform provides centralized control over litigation cases, enhancing visibility into outside counsel activities and offering instant access to case information. By streamlining document storage, retrieval, deadlines, and tasks, the platform enables collaborative management of cases among all stakeholders. This results in increased efficiency, reduced billable costs, and allows legal departments to focus on strategic projects.

PopBookings is a cloud-based staffing solution company that specializes in automating the hiring process for temporary and promotional staffing agencies. Founded in 2014 and headquartered in Lenexa, Kansas, PopBookings offers a comprehensive platform designed to simplify the booking and communication with promotional staff. Its features include database management, a custom-branded talent portal, drag-and-drop scheduling, geo check-ins, and an event dashboard with status alerts. By connecting agencies and brands with event workers, PopBookings facilitates the organization of events, helping to celebrate brands through effective staffing solutions.

CoverCress Inc. specializes in developing and commercializing field pennycress as a sustainable oilseed crop for industrial oils and livestock feed. Founded in 2013, the company is headquartered in Saint Louis, Missouri.

Tallyfy, Inc. is a company that develops online business process improvement and workflow management software, founded in 2014 and headquartered in St. Louis, Missouri, with an additional office in San Francisco, California. Its cloud-based platform focuses on automating and optimizing recurring workflows, allowing organizations, from Fortune 500 companies to small startups, to track processes in real-time, thereby reducing manual updates and enhancing efficiency. Tallyfy's software specializes in areas such as client onboarding, customer success, and compliance, enabling businesses to minimize human errors and streamline operations. Users can create templates, automate processes with conditional rules, and continuously improve workflows through feedback and metrics, fostering a culture of operational excellence.

Strayos Inc., founded in 2016 and based in St. Louis, Missouri, specializes in developing aerial data analytics software for various industries including mining, drilling, blasting, quarrying, and oil and gas exploration. The company's platform utilizes image processing and artificial intelligence to provide highly accurate survey data analytics, transforming job site insights through 3D visual AI. Key offerings include smart drill data analysis using measurement-while-drilling techniques, 3D Blast Profile for optimizing blast patterns, and Muckpile and Rock Size Analysis through advanced machine learning. These solutions aim to reduce costs, improve productivity, and enhance safety by delivering actionable insights that maximize operational excellence.

BenchmarkONE is a St. Louis, Missouri-based company that specializes in developing sales and marketing automation software for small and mid-sized businesses. Founded in 2010 and previously known as Hatchbuck, Inc., BenchmarkONE provides an all-in-one customer relationship management (CRM) platform that includes features for sales automation, real-time activity monitoring, and email marketing. Its user-friendly interface allows businesses to create and manage campaigns, track leads, and analyze performance metrics effectively. The software is designed to streamline the sales process, enhance customer engagement, and facilitate the growth of relationships into sales. As of June 2020, BenchmarkONE operates as a subsidiary of Benchmark Internet Group, LLC.

Better Weekdays, Inc. operates an online career services platform and mobile application known as The Whether. Founded in 2011 and based in Saint Louis, Missouri, the company provides a comprehensive suite of applications aimed at preparing students for employment. Its flagship product, Mentor Spaces, is a virtual mentorship platform that assists companies in identifying, hiring, and retaining underrepresented talent. In addition to this, Better Weekdays offers self-assessment, job matching, and career development services to both students and professionals. By leveraging personalized content marketing, the company helps university recruiters reduce their cost per hire while enabling employers to attract and retain top talent.

Olio City, Inc. is a company based in Saint Louis, Missouri, that specializes in developing an online travel guide application aimed at enhancing city exploration. Founded in 2014, the app offers personalized city discovery by integrating curated content with an algorithm that adapts to individual user preferences. It features a comprehensive database of local experiences, including restaurants, attractions, and nightlife events, all curated by local experts and cultural enthusiasts. The application tailors recommendations based on users’ tastes, ensuring that whether one is interested in jazz music or Japanese cuisine, the suggestions align with their interests. Olio City enables users to seamlessly explore cities, uncovering nearby hotspots and enriching their travel experiences.

Recursive Labs offers a patented Visual Customer Engagement Platform that enables secure real-time co-browsing between users and customer service representatives. Its solutions include Realtime for Web and document sharing, Replay Social for viral marketing, Replay Support for time-shifted messaging, and Replay Enterprise for internal communications. Available as Software-as-a-service, the platform aims to enhance sales and support efforts across digital channels.

SanusEO, LLC is a St. Louis-based company that specializes in developing a mobile patient engagement platform (PEP) designed to enhance communication and care between patients and healthcare providers. Founded in 2012, the platform employs data analytics to deliver daily alerts and real-time participant data to care teams, facilitating timely interventions for chronic disease management. SanusEO offers targeted programs such as transition care for patients recently discharged from hospitals and bootcamps for newly diagnosed or at-risk individuals. The platform promotes behavior modification in key health areas, including medication adherence, vital monitoring, diet, and physical activity, with capabilities for multi-language support. By streamlining engagement and intervention processes, SanusEO aims to improve patient outcomes while reducing healthcare costs.

Janus Choice, LLC is a healthcare technology company focused on enhancing the hospital discharge process and facilitating informed transitions to post-discharge care. Founded in 2014 and headquartered in Rockford, Illinois, the company offers an innovative search engine that utilizes a patentable algorithm to match patients' clinical and social needs with appropriate skilled nursing facilities. This platform empowers patients and their families to make informed decisions about their care options while still in the hospital, thereby improving the overall patient experience and reducing hospital length of stay. By streamlining the discharge process, Janus Choice benefits not only patients and their families but also hospitals and skilled nursing facilities, contributing to a more efficient continuum of care. The company was established by individuals who recognized the challenges of navigating post-discharge care for their loved ones, leading to a solution that addresses the needs of all stakeholders involved in the healthcare transition process.

LocalRaces.com LLC is a technology company based in Joplin, Missouri, that specializes in online race registration and event management services. Established in 2014, the company provides a comprehensive platform designed to enhance the experience of participants in endurance events such as running, cycling, and triathlons. LocalRaces.com facilitates race management for directors by offering an all-in-one web-based software suite that includes tools for registration, volunteer coordination, sponsorship, and vendor management. The platform processes registrations both online and onsite and acts as a payment facilitator, charging a fee to registrants while delivering valuable event management solutions to race directors. Additionally, LocalRaces.com boasts the largest network of local running and cycling communities in the U.S., hosting thousands of event and club profiles. Athletes benefit from web-based tools and mobile applications to manage their racing itineraries, results, and training goals. The company also generates revenue through featured event listings, display advertisements, and partnerships within the running shoe and apparel market.

Sparo Labs is a St. Louis-based startup founded in 2012 that focuses on advancing respiratory care through innovative technology. The company's flagship product, Wing, is a pocket-sized device connected to a smartphone, designed to measure lung function with medical-grade accuracy. This device empowers patients to understand, track, and manage their asthma effectively, thereby reducing the fear and uncertainty associated with the condition. By allowing users to monitor their lung function, manage medications, and identify triggers and symptoms, Sparo Labs aims to transform the asthma management landscape and enhance the quality of life for individuals living with respiratory conditions.

EternoGen is a medical biotechnology company founded in 2009 and headquartered in Columbia, Missouri. The company specializes in the design and manufacture of collagen scaffolds for therapeutic applications in soft tissue. EternoGen focuses on research and development, leveraging its expertise in clinical market evaluation, material science, and biological engineering to advance its clinical development model. Its innovative liquid collagen tissue products offer an alternative to traditional aesthetic treatments, enabling easy injection that creates an immediate natural collagen scaffold upon contact with skin. This process not only lifts wrinkled skin but also inhibits degradation, allowing dermal cells to gradually infill the scaffold over time, thereby restoring youthful fullness, texture, and elasticity to the skin.

MedAware Solutions, Inc. is a healthcare technology company based in St. Louis, Missouri, founded in 2014. It specializes in providing a comprehensive platform that facilitates communication and coordination among healthcare teams, including providers, payers, patients, and their families. The company's flagship product, mViva, serves as an all-in-one care coordination tool that allows multi-disciplinary teams to engage with patients throughout the continuum of care. This secure, HIPAA-compliant platform enables users to capture and share data efficiently, fostering collaboration and enhancing patient outcomes. By empowering individuals to participate in real-time conversations and access connected care, MedAware Solutions aims to optimize clinical resources and reduce healthcare costs.

FocalCast LLC, founded in 2013 and located in St. Louis, Missouri, is a technology company that specializes in developing an interactive web-based platform for market research. The platform allows users to simultaneously share and annotate documents and whiteboards in real time from any device, enhancing collaboration for global brands and marketing agencies. FocalCast's offerings include tools for stimuli and content presentation, live annotations, project management, and polling and data services. Users can easily connect with research participants without needing to download additional software, facilitating seamless presentations directly from smartphones or tablets to display devices like projectors or smart TVs.

FinLocker, LLC is a financial technology company based in St. Louis, Missouri, founded in 2014. It specializes in developing a consumer-enabled financial data platform that enhances the loan process for mortgages and various financial products. FinLocker provides a personal financial assistant tool that captures essential borrower data with consumer consent, utilizing intelligent analytics to offer tailored loan product recommendations based on individual financial profiles. Its solutions aim to streamline lending processes by improving data collection, verification, and analytics, thereby reducing costs, time, and risks for lenders. Additionally, FinLocker enhances the borrower experience by enabling consumers to manage their finances more effectively, apply for loans with reduced documentation hassles, and control data sharing.

Nanopore Diagnostics, LLC is a St. Louis-based company founded in 2011 that specializes in developing rapid and portable diagnostic products for bacterial infections. Its flagship product, The iNDxer, is a nanopore sensor designed to count dilute amounts of nucleic acid biomarkers directly in minimally processed samples. This technology allows for the detection of RNA markers specific to pathogenic bacteria, enabling physicians to accurately identify the presence of harmful microbes. By providing timely and precise diagnostic information, Nanopore Diagnostics aims to assist healthcare providers in making informed antibiotic decisions, ultimately reducing healthcare costs and combating antibiotic resistance. The company's focus on delivering microbiology lab-quality testing at the patient's side represents a significant advancement in the field of diagnostics.

PayIt specializes in modernizing government payment systems by offering a cloud-based platform that enables digital transactions for various services such as taxes, utilities, courts, DMV, and outdoors. The company serves over 100 million residents across North America, improving operational efficiency and enhancing citizen satisfaction.

Founded in 2013, Bonfyre operates an employee engagement platform that facilitates communication, recognition, feedback, events, and more. Its mobile-first, real-time tools help enterprises build camaraderie, align culture, and drive HR business intelligence.

MedSocket is a company that specializes in clinical decision support systems aimed at enhancing the efficiency and quality of patient care. It offers two patented technologies: the 1-Click Decision Support (1-CDS) system and a medical search engine called 1-Search. Designed by clinicians for clinicians, these tools provide rapid access to evidence-based information at the point of care, addressing the urgent information needs of healthcare providers. Both technologies have been successfully piloted at the University of Missouri Health System, demonstrating their potential to improve healthcare decisions, reduce errors, and ultimately enhance patient outcomes. MedSocket was founded by Dr. Karl Kochendorfer, who recognized the challenges healthcare providers faced in accessing timely information, and was later joined by Matt Botkin and Jayne Williams to bring together expertise in business and information science. The company aims to alleviate the burden on clinicians by streamlining information retrieval and decision-making processes in healthcare settings.

MedSocket is a company that specializes in clinical decision support systems aimed at enhancing the efficiency and quality of patient care. It offers two patented technologies: the 1-Click Decision Support (1-CDS) system and a medical search engine called 1-Search. Designed by clinicians for clinicians, these tools provide rapid access to evidence-based information at the point of care, addressing the urgent information needs of healthcare providers. Both technologies have been successfully piloted at the University of Missouri Health System, demonstrating their potential to improve healthcare decisions, reduce errors, and ultimately enhance patient outcomes. MedSocket was founded by Dr. Karl Kochendorfer, who recognized the challenges healthcare providers faced in accessing timely information, and was later joined by Matt Botkin and Jayne Williams to bring together expertise in business and information science. The company aims to alleviate the burden on clinicians by streamlining information retrieval and decision-making processes in healthcare settings.

Orange EV manufactures heavy-duty industrial electric vehicles. Established in 2012, the company designs, manufactures, delivers, and services Class 8 trucks, offering charging solutions, demo drives, warranties, financial incentives, and financing options.

Euclises Pharmaceuticals, Inc. is a biopharmaceutical company focused on researching, developing, and commercializing innovative medicines for inflammation and oncology. Founded in 2011 and headquartered in Saint Louis, Missouri, the company aims to create novel pain and cancer treatments that demonstrate superior safety profiles compared to existing medications. Euclises Pharmaceuticals leverages groundbreaking inventions from Dr. John Talley, a renowned medicinal chemist known for his development of several approved drugs, including Celebrex. The company's research is centered on compounds that promise enhanced efficacy and safety, positioning Euclises as a significant player in the pharmaceutical industry. It operates out of the BioGenerator Accelerator Labs, fostering a collaborative environment for its innovative pursuits.

Confluence Life Sciences, Inc. is a drug discovery company based in Saint Louis, Missouri, specializing in the design and development of mechanistically novel kinase inhibitors for human and animal health care. Founded in 2010, the company utilizes its KINect technology platform to identify and develop new drugs targeting key enzymes involved in cancer growth, survival, and metastasis, as well as in chronic inflammatory diseases. Confluence Life Sciences distinguishes itself by focusing on novel binding sites and previously undrugged kinases, addressing challenges that other programs have overlooked. The company is supported by a team of experts with extensive pharmaceutical experience in kinase inhibitor discovery and development, enabling it to pursue innovative strategies and targets. Confluence Life Sciences aims to establish scientific and business collaborations to enhance its program pipeline, which follows a cycle of discovery, development, and partnership to meet unmet medical needs.

GeneriCo, LLC is a pharmaceutical company that specializes in the development and marketing of generic medications. Founded in 2013 and headquartered in Saint Louis, Missouri, with additional offices in Bengaluru, India; Italy; and South Korea, GeneriCo focuses on foundational medicines across various therapeutic areas, including cardiovascular health, pain management, central nervous system disorders, oncology, and aging-related conditions. The company distinguishes itself by targeting niche generic pharmaceuticals that have been overlooked by larger competitors, particularly those that involve complex formulations and innovative drug delivery technologies. This strategic focus allows GeneriCo to address specific market needs that are often neglected by mid-sized and large generic companies. GeneriCo serves a global customer base, providing essential medications that contribute to improved health outcomes.

SanusEO, LLC is a St. Louis-based company that specializes in developing a mobile patient engagement platform (PEP) designed to enhance communication and care between patients and healthcare providers. Founded in 2012, the platform employs data analytics to deliver daily alerts and real-time participant data to care teams, facilitating timely interventions for chronic disease management. SanusEO offers targeted programs such as transition care for patients recently discharged from hospitals and bootcamps for newly diagnosed or at-risk individuals. The platform promotes behavior modification in key health areas, including medication adherence, vital monitoring, diet, and physical activity, with capabilities for multi-language support. By streamlining engagement and intervention processes, SanusEO aims to improve patient outcomes while reducing healthcare costs.

CoverCress Inc. specializes in developing and commercializing field pennycress as a sustainable oilseed crop for industrial oils and livestock feed. Founded in 2013, the company is headquartered in Saint Louis, Missouri.

BenchmarkONE is a St. Louis, Missouri-based company that specializes in developing sales and marketing automation software for small and mid-sized businesses. Founded in 2010 and previously known as Hatchbuck, Inc., BenchmarkONE provides an all-in-one customer relationship management (CRM) platform that includes features for sales automation, real-time activity monitoring, and email marketing. Its user-friendly interface allows businesses to create and manage campaigns, track leads, and analyze performance metrics effectively. The software is designed to streamline the sales process, enhance customer engagement, and facilitate the growth of relationships into sales. As of June 2020, BenchmarkONE operates as a subsidiary of Benchmark Internet Group, LLC.

SynerZ Medical, Inc. develops medical device for the treatment of obesity and type 2 diabetes. The company was incorporated in 2013 and is based in St. Louis, Missouri.

PFITR, Inc. is a technology company headquartered in Chesterfield, Missouri, specializing in integrated mobile solutions for public funds investment managers. Founded in 2013, PFITR offers a software-as-a-service platform designed to assist public fiduciaries—such as treasurers and directors of finance—in managing trillions of taxpayer dollars. Its flagship product, the Bond Price Validation Tool, provides users with essential valuation metrics derived from market transactions, enabling informed investment decisions while adhering to mandates of safety, liquidity, and yield. The software enhances transparency by offering analytics and internal controls that mitigate risks associated with hidden commissions and poor timing in investment purchases. By leveraging proprietary data from recognized partners, PFITR aims to empower public fiduciaries to optimize their portfolios and ensure accountability to constituents and auditors. The company has garnered interest from early-stage investors and is actively building its customer base, targeting a significant penetration of U.S. public entities over the coming years.

ImmunoPhotonics, Inc. is a biotechnology company focused on developing innovative immunotherapy-based treatments for cancer, specifically targeting metastatic solid tumors. Founded in 2008 and headquartered in Columbia, Missouri, the company has created a proprietary drug product that functions as a minimally invasive autologous cancer vaccine. This treatment involves the intratumoral injection of a carbohydrate polymer following tumor ablation, which harnesses the immune system's response to tumor-associated neoantigens released during the process. By doing so, ImmunoPhotonics aims to generate a systemic anti-tumor immune response, facilitating the treatment of late-stage metastatic cancers. The company has established a strategic partnership with Veterinary Cancer Therapeutics, LLC, enhancing its potential for clinical application.

Kultevat, Inc. is a biotechnology company focused on the breeding and cultivation of industrially relevant dandelion varieties, specifically the Russian Dandelion, to serve as a sustainable source of natural rubber. Founded in 2013 and based in Portageville, Missouri, the company engages in the processing and extraction of dandelion rubber and related co-products, offering latex and bulk rubber products for various applications, including gloves, medical devices, automotive parts, and biofuels. Kultevat aims to provide an environmentally friendly alternative to synthetic rubber, contributing to reduced ecological impact while serving agricultural markets in the United States, Canada, and Europe. Its innovative approach combines crop improvement and strain selection to enhance the performance and versatility of natural rubber.

Euclises Pharmaceuticals, Inc. is a biopharmaceutical company focused on researching, developing, and commercializing innovative medicines for inflammation and oncology. Founded in 2011 and headquartered in Saint Louis, Missouri, the company aims to create novel pain and cancer treatments that demonstrate superior safety profiles compared to existing medications. Euclises Pharmaceuticals leverages groundbreaking inventions from Dr. John Talley, a renowned medicinal chemist known for his development of several approved drugs, including Celebrex. The company's research is centered on compounds that promise enhanced efficacy and safety, positioning Euclises as a significant player in the pharmaceutical industry. It operates out of the BioGenerator Accelerator Labs, fostering a collaborative environment for its innovative pursuits.

Lumate, LLC is a technology company that specializes in a context-driven mobile advertising platform aimed at enhancing audience engagement for advertisers. Established in 2008 and headquartered in Saint Louis, Missouri, with an additional office in Rolla, the company provides a range of innovative products. These include AdTrade, which serves as a bidding engine that enriches mobile advertising through data analysis of user behavior, AdMotive, a self-service portal that allows advertisers to customize campaign reach, and DataWell, an API and SDK intended for publishers and data providers to monetize actionable audience data. By leveraging geo-location and real-time bidding technologies, Lumate enables advertisers, ad networks, and media buyers to effectively target their desired audiences within the mobile advertising landscape.

Adarza BioSystems is an early-stage medical diagnostics company based in St. Louis, Missouri, that specializes in developing a rapid and label-free biological assay platform for clinical and point-of-care samples. Founded in 2008, the company utilizes its innovative arrayed imaging reflectometry technology to enable the simultaneous detection of hundreds of analytes from a single drop of fluid. This platform allows healthcare professionals to conduct sophisticated tests in a matter of minutes, ensuring high sensitivity and specificity in the detection of multiplexed proteins. Adarza BioSystems aims to enhance diagnostic capabilities, improving patient outcomes through quicker and more accurate testing.

EternoGen is a medical biotechnology company founded in 2009 and headquartered in Columbia, Missouri. The company specializes in the design and manufacture of collagen scaffolds for therapeutic applications in soft tissue. EternoGen focuses on research and development, leveraging its expertise in clinical market evaluation, material science, and biological engineering to advance its clinical development model. Its innovative liquid collagen tissue products offer an alternative to traditional aesthetic treatments, enabling easy injection that creates an immediate natural collagen scaffold upon contact with skin. This process not only lifts wrinkled skin but also inhibits degradation, allowing dermal cells to gradually infill the scaffold over time, thereby restoring youthful fullness, texture, and elasticity to the skin.

Traxxsson is a biotechnology company that develops diagnostics for cancer using protein biomarkers. It uses a proprietary panel of biomarkers to identify at-risk patients who have questionable radiology images. It has three tests: PRO CancSure to identify prostate cancer patients in need of aggressive treatment, BRE CancSure to confirm the presence of breast cancer in women with positive mammograms, and LNG CancSure to confirm the presence of lung cancer in patients with positive low-density CAT scan results. The company was founded in 2009 and is based in St. Louis, Missouri.

MediBeacon is an optical diagnostics company developing real-time organ function monitoring solutions. Its portfolio focuses on fluorescent tracer-agent systems that enable continuous assessment of kidney function, including the NIC-Kidney device for monitoring glomerular filtration rate in preclinical settings and a renal function system that pairs an optical skin sensor with a proprietary light-activated agent to provide continuous real-time kidney monitoring in clinical environments. The company also maintains a pipeline of light-activated agents for physiological monitoring, surgical guidance and imaging. By commercializing biocompatible optical agents, MediBeacon aims to support critical care and surgical decision-making, enhancing dosing accuracy and patient outcomes in ICUs and operating suites. The technology supports monitoring of kidney and other vital organ functions, helping clinicians intervene in a timely manner.

Kypha Inc. is a life sciences company focused on the discovery, development, and commercialization of in-vitro diagnostic biomarker tests targeting inflammation and autoimmune disorders. Based in St. Louis, Missouri, the company offers the COMP ACT System, which enhances the monitoring and treatment of various health conditions, including lupus, stroke, traumatic brain injury, preeclampsia, infection, kidney disease, and transplant rejection. Through its innovative platform, Kypha provides rapid and accurate assessments of inflammation levels, enabling healthcare professionals to make timely and informed clinical decisions. The company's approach facilitates testing across diverse settings, from home health care to clinical laboratories, ultimately aiming to improve patient outcomes by optimizing treatment strategies based on real-time immune insights. Since its incorporation in 2009, Kypha has attracted significant funding and built a strong network of scientific and clinical expertise to support its mission.

Founded in 2013, Bonfyre operates an employee engagement platform that facilitates communication, recognition, feedback, events, and more. Its mobile-first, real-time tools help enterprises build camaraderie, align culture, and drive HR business intelligence.

Confluence Life Sciences, Inc. is a drug discovery company based in Saint Louis, Missouri, specializing in the design and development of mechanistically novel kinase inhibitors for human and animal health care. Founded in 2010, the company utilizes its KINect technology platform to identify and develop new drugs targeting key enzymes involved in cancer growth, survival, and metastasis, as well as in chronic inflammatory diseases. Confluence Life Sciences distinguishes itself by focusing on novel binding sites and previously undrugged kinases, addressing challenges that other programs have overlooked. The company is supported by a team of experts with extensive pharmaceutical experience in kinase inhibitor discovery and development, enabling it to pursue innovative strategies and targets. Confluence Life Sciences aims to establish scientific and business collaborations to enhance its program pipeline, which follows a cycle of discovery, development, and partnership to meet unmet medical needs.

Euphrates Vascular is a medical technology company based in St. Louis, Missouri, that focuses on innovative solutions for the treatment of stroke, heart disease, and other conditions. The company has developed a proprietary magnetically-enhanced diffusion (MED) system that utilizes magnet-based technology to dissolve blood clots more rapidly than existing treatment options. This system aims to improve the efficacy of FDA-approved clot-busting medications, potentially reducing mortality rates associated with stroke and cardiovascular diseases. In addition to the MED system, Euphrates Vascular offers MED MicroBeads, which are designed to deliver therapeutic agents directly to clots during thrombolysis therapy, and a touch screen-operated MED Workstation. Founded by physicists with extensive experience in medical technology, the company continues to advance its pioneering approaches in the healthcare sector, attracting interest from investors and media alike.