Missouri Technology Corporation

Missouri Technology Corporation, established in 2005 and based in Jefferson City, Missouri, is a venture capital firm dedicated to promoting entrepreneurship and facilitating the growth of high-tech companies within the state. The organization focuses on investing in companies operating in various sectors, including life sciences, animal health, applied engineering, biomedical science, defense and homeland security, plant science, and technology. By supporting emerging businesses in these fields, Missouri Technology Corporation aims to strengthen the state's economy and foster innovation.

Dan Cobb

Vice Chairman and Board Member

Jack Scatizzi Ph.D

Executive Director

Past deals in Missouri

backstitch

Venture Round in 2024
Backstitch Inc. operates a platform focused on personalized employee communications, catering specifically to HR and internal communications teams. The company's platform allows users to create effective business communications, providing features such as push notifications, internal content delivery, and industry news. Additionally, Backstitch enables users to analyze trends and behaviors within their organizations, identify allies across departments, and measure the return on investment of their communications and engagement efforts. The company also develops an application that integrates a curated media monitoring platform. Founded in 2012, Backstitch is based in Kansas City, Missouri.

Amptify

Grant in 2023
Amptify provides hearing healthcare services through a technology platform that utilizes mobile devices, the internet, video, and phone communication. Founded by a prominent aural rehabilitation research team from the Audiovisual Speech Perception Laboratory at Washington University in St. Louis, Amptify has established itself as a leader in comprehensive hearing healthcare. The company's evidence-based programs and proprietary digital toolkit are designed to assist individuals with hearing loss, enhancing their ability to communicate and improving their overall social, psychological, and physical well-being. This approach enables hearing healthcare specialists to deliver personalized rehabilitation tailored to the needs of their patients.

Digital Sandbox KC

Grant in 2022
Digital Sandbox KC is an incubator based in Kansas City, Missouri, established in 2013. The organization focuses on supporting early-stage commercialization processes by providing proof-of-concept resources. It offers access to technology, as well as expertise in business and market validation, which are crucial for startups. Digital Sandbox KC assists entrepreneurs with prototyping and beta testing services, facilitating the development and refinement of innovative ideas. Through its comprehensive support, the incubator aims to foster the growth of emerging businesses in the region.

Arch Grants

Grant in 2022
Arch Grants is a nonprofit organization that accelerates economic development and community revitalization by providing $50,000 equity-free grants and pro bono support services to entrepreneurs who locate their early-stage businesses in St. Louis. Through its rigorously competitive Global Startup Competition, Arch Grants retains and attracts the most innovative entrepreneurs to the St. Louis region. This program is an aggressive effort to inspire the next generation of employers, civic leaders, and philanthropists for St. Louis. The industry-agnostic Global Startup Competition is year-round, with grants awarded once in the spring and again in the fall. Arch Grants funds innovative technologies, products, and services wrapped within scalable business models that have the potential to make a national or international impact.

Launch KC

Grant in 2022
Launch KC is to attract and retain high-growth tech startups to Downtown Kansas City, Missouri. Meet your new colleagues and have the space you need. They’ll match your firm to seasoned business leaders to give you resources. Expand your business affordably. Their Data Center gives you better computing power, hosting, and data storage. Access higher bandwidth and work where you want, when you want with the freedom of their downtown wireless district. Grow your business. Take advantage of their tailored development incentives for your IT company. Test your ideas with state of the art equipment. Meet mentors and professionals who will develop your business. Partner with KCMO to develop or test an innovative solution for the City.

The eFactory

Grant in 2022
The eFactory is a business resource center located in southwest Missouri, specifically designed to support entrepreneurs and startups. It offers a 12-week intensive accelerator program aimed at jumpstarting emerging companies. Participants benefit from financial support, dedicated office space, and personalized mentoring, as well as business consulting services. The eFactory also facilitates introductions to potential follow-on funding sources and provides access to a recreation center, enhancing the networking opportunities available to its members. Through these resources, the eFactory fosters a collaborative environment that aims to promote innovation and growth within the local entrepreneurial ecosystem.

Plastomics

Series A in 2021
Plastomics Inc. is a biotechnology company specializing in chloroplast genetic engineering to enhance crop performance. Founded in 2016 and based in St. Louis, Missouri, the company focuses on gene stacking and rapid breeding to improve yield production and nutritional quality. Its innovative technology platform allows for the precise insertion of beneficial traits into the chloroplasts of plant cells, facilitating the development of more effective biotech crops. This approach not only addresses current industry challenges but also eliminates cross-pollination, enabling clients to achieve trait expression in plants more reliably. Additionally, Plastomics' unique method of maternal inheritance streamlines breeding timelines and reduces costs, making it a valuable partner for seed companies in the agricultural sector.

Covercress

Venture Round in 2018
CoverCress Inc. is a biotechnology company based in St. Louis, Missouri, focused on developing and commercializing field pennycress as an oilseed crop. Founded in 2013, the company aims to produce oil for industrial and renewable fuels, as well as meal for nutritious livestock feed. CoverCress specializes in crop breeding services that enhance soil cover during corn harvest and soybean planting, allowing farmers to maximize yields through sustainable agricultural practices. The company is dedicated to utilizing low-input methods to create a feedstock for low carbon intensity biofuels, contributing to more efficient and environmentally friendly agricultural solutions.

Digital Sandbox KC

Grant in 2018
Digital Sandbox KC is an incubator based in Kansas City, Missouri, established in 2013. The organization focuses on supporting early-stage commercialization processes by providing proof-of-concept resources. It offers access to technology, as well as expertise in business and market validation, which are crucial for startups. Digital Sandbox KC assists entrepreneurs with prototyping and beta testing services, facilitating the development and refinement of innovative ideas. Through its comprehensive support, the incubator aims to foster the growth of emerging businesses in the region.

PatientsVoices

Seed Round in 2018
PatientsVoices, LLC, founded in 2013 and based in Parkville, Missouri, operates a healthcare language processing platform that transforms patient feedback into actionable insights. The company utilizes advanced data analytics to process information from various sources, including surveys, social media posts, and complaints. This platform is designed to automatically categorize feedback into improvement priorities from the patient's perspective, demonstrating to hospital administrators how to enhance patient satisfaction. By summarizing patient responses into an easily digestible format, PatientsVoices equips healthcare providers with the tools needed to improve patient experiences and potentially increase Medicare reimbursements. The platform is currently being tested in hospitals to further validate its effectiveness.

Canopy Biosciences

Series A in 2018
Canopy Biosciences is a biotechnology company specializing in research tools for gene editing, molecular biology, and personalized medicine. Founded in 2016 and headquartered in St. Louis, Missouri, the company offers a range of products and services designed to enhance scientific discovery in biomedical research. Its gene editing technology, known as TUNR, facilitates targeted modifications in the genome by inserting polyA tracks into specific coding regions, which reduces mRNA levels and subsequently suppresses protein expression. This innovative approach supports researchers at universities, research institutions, and within the biotechnology and pharmaceutical sectors, advancing the fields of genetic engineering and gene expression analysis. Canopy Biosciences operates as a subsidiary of Bruker Corporation.

Geneoscopy

Venture Round in 2018
Geneoscopy, LLC, based in Saint Louis, Missouri, specializes in developing non-invasive diagnostic tests aimed at preventing, detecting, and guiding treatment for gastrointestinal diseases, particularly colorectal cancer. Founded in 2015, the company utilizes a proprietary platform that extracts stool-derived eukaryotic RNA (seRNA) to create a multi-target RNA biomarker panel. This innovative approach allows for the identification of colorectal cancer by capturing the effects of DNA mutations associated with the disease. Geneoscopy's technology not only enhances screening compliance but also facilitates the early detection of colorectal neoplasms, ultimately aiming to reduce morbidity and mortality linked to colorectal cancer. The company is also exploring additional applications of its technology for related gastrointestinal conditions.

Lean Media

Seed Round in 2018
Lean Media, Inc. specializes in cookieless digital advertising services tailored for agribusiness and rural community advertisers. Founded in 2014 and headquartered in Chesterfield, Missouri, the company utilizes a sophisticated audience targeting platform that leverages geo-targeting technology alongside consumer psychographic, demographic, and behavioral insights. By comparing IP addresses with consumer databases, Lean Media enables advertisers to engage individuals at the consumer level, as well as target specific business categories or locations. Their innovative approach aims to enhance engagement and minimize waste in advertising campaigns, providing a reliable solution for reaching target audiences effectively.

Keybot

Pre Seed Round in 2018
Keybot, Inc. specializes in designing and manufacturing rental access robots that streamline access to rental properties through integrated hardware and software solutions. Established in 2018 and headquartered in St. Peters, Missouri, with additional locations in Kansas City, Missouri, and London, United Kingdom, the company focuses on automating self-showings and facilitating access for renters and maintenance personnel. Keybot's innovative products allow property managers and rental owners to share digital keys with verified third parties, manage access remotely, and maintain detailed access logs, enhancing security and convenience for users. The company also operates a production office in Taipei City, Taiwan, to support its manufacturing needs.

Tallyfy

Seed Round in 2017
Tallyfy, Inc. is a software company that specializes in online business process improvement and workflow management. Founded in 2014 and headquartered in St. Louis, Missouri, with an additional office in San Francisco, Tallyfy offers a cloud-based platform that enables organizations to streamline their recurring workflows and enhance process management. The software provides a user-friendly dashboard for real-time tracking of processes, allowing businesses to digitize workflows, automate conditional rules, and eliminate manual updates. Tallyfy serves a diverse clientele, ranging from Fortune 500 companies to small startups, and emphasizes the importance of process optimization in achieving efficiency and reducing human errors. Users can initiate a trial of the platform to explore its capabilities, which also include continuous process improvement through metrics and feedback.

Covercress

Venture Round in 2017
CoverCress Inc. is a biotechnology company based in St. Louis, Missouri, focused on developing and commercializing field pennycress as an oilseed crop. Founded in 2013, the company aims to produce oil for industrial and renewable fuels, as well as meal for nutritious livestock feed. CoverCress specializes in crop breeding services that enhance soil cover during corn harvest and soybean planting, allowing farmers to maximize yields through sustainable agricultural practices. The company is dedicated to utilizing low-input methods to create a feedstock for low carbon intensity biofuels, contributing to more efficient and environmentally friendly agricultural solutions.

Tallyfy

Seed Round in 2017
Tallyfy, Inc. is a software company that specializes in online business process improvement and workflow management. Founded in 2014 and headquartered in St. Louis, Missouri, with an additional office in San Francisco, Tallyfy offers a cloud-based platform that enables organizations to streamline their recurring workflows and enhance process management. The software provides a user-friendly dashboard for real-time tracking of processes, allowing businesses to digitize workflows, automate conditional rules, and eliminate manual updates. Tallyfy serves a diverse clientele, ranging from Fortune 500 companies to small startups, and emphasizes the importance of process optimization in achieving efficiency and reducing human errors. Users can initiate a trial of the platform to explore its capabilities, which also include continuous process improvement through metrics and feedback.

BenchmarkONE

Series A in 2017
BenchmarkONE develops sales and marketing automation software tailored for small and mid-sized businesses. The company offers an integrated platform that includes customer relationship management (CRM) tools and sales automation features, allowing users to monitor contacts' activities, track deals, manage communications, and segment their audience. Additionally, BenchmarkONE provides email marketing capabilities with a user-friendly drag-and-drop email builder and marketing automation tools designed to engage visitors, prioritize leads, and optimize campaign investments. Originally known as Hatchbuck, Inc., the company rebranded to BenchmarkONE in June 2020 and has been operational since 2010, with its headquarters in St. Louis, Missouri. As of September 2019, BenchmarkONE functions as a subsidiary of Benchmark Internet Group, LLC.

Better Weekdays

Grant in 2016
Better Weekdays, Inc. operates an online career services platform and mobile application known as The Whether, aimed at enhancing the job placement process for students and employers. Founded in 2011 and based in Saint Louis, Missouri, the company focuses on reducing hiring costs for university recruiters through personalized content marketing tailored to college students. It offers a range of services including self-assessment, job matching, and career development resources for both students and professionals. Additionally, Better Weekdays develops Mentor Spaces, a virtual mentorship platform that assists companies in finding, hiring, and retaining underrepresented talent, thereby promoting diversity in the workforce.

Recursive Labs

Grant in 2016
Recursive Labs, Inc. specializes in a visual customer engagement platform that enhances real-time interactions between businesses and their customers. The company's technology enables co-browsing, allowing users to share their online experiences with customer service, sales, and technical support representatives, as well as with family and friends. Key offerings include Realtime, a solution for collaborative online shopping, and Replay Support, which allows customers to record and share their shopping experiences for better assistance. Additionally, Recursive Labs provides Replay Social, a tool that integrates voice, web, and video for enhanced marketing on social platforms, and Replay Enterprise, aimed at improving internal communications. These solutions are delivered through a Software-as-a-Service model, ensuring accessibility across various internet-connected devices. Founded in 2011 and based in St. Louis, Missouri, Recursive Labs was previously known as Click With Me Now, Inc. before rebranding in 2015.

Olio City

Grant in 2016
Olio City, Inc. is a company that specializes in an online travel guide application aimed at enhancing city exploration. Founded in 2014 and based in Saint Louis, Missouri, the application provides users with personalized city discovery experiences by utilizing curated content from local experts and cultural enthusiasts. It features a comprehensive database that includes recommendations for attractions, restaurants, shopping, and nightlife events, all tailored to individual preferences. The app employs an algorithm that learns users' tastes, allowing it to suggest relevant experiences based on their interests, whether they are seeking jazz music or specific culinary options. This innovative approach enables users to navigate cities effectively and discover unique local hotspots.

SanusEO

Seed Round in 2016
SanusEO, LLC is a mobile health technology company based in St. Louis, Missouri, specializing in a text-based patient engagement platform (PEP) designed to enhance communication between patients and care teams. Founded in 2012, SanusEO's platform supports healthcare providers, chronic disease patients, and payers by delivering daily alerts and real-time data to care teams, facilitating both immediate and long-term intervention strategies. The platform is particularly effective for managing patients transitioning from hospital care and those newly diagnosed with chronic conditions. By utilizing mobile texting programs, SanusEO aims to modify patient behaviors related to medication adherence, vital monitoring, diet, physical activity, and overall communication with healthcare providers. The approach targets various chronic diseases, including diabetes and congestive heart failure, and offers multi-language capabilities to cater to diverse patient populations.

Janus Choice

Seed Round in 2016
Janus Choice, LLC is a healthcare solutions provider that enhances the hospital discharge process by empowering patients to select suitable skilled nursing facilities. The company offers an interactive search engine equipped with a patentable algorithm, which matches patients' clinical and social needs with available services at various facilities. This technology allows patients and their families to make informed decisions while still in the hospital, ultimately reducing hospital length of stay and improving patient experience. Founded in 2014 and headquartered in St. Louis, Missouri, Janus Choice aims to facilitate seamless transitions between different care settings, benefiting patients, hospitals, and skilled nursing facilities alike. The company was established by individuals who recognized the challenges faced during the discharge process and sought to create a solution that addresses the needs of all parties involved.

LocalRaces.com

Grant in 2016
LocalRaces.com LLC operates a comprehensive online platform focused on race registration and event management services, catering primarily to the endurance event market. Established in 2014 and headquartered in Joplin, Missouri, the company provides race directors with tools to enhance participant experiences while streamlining event management processes. It facilitates registrations for runners, cyclists, and triathletes, handling both online and onsite transactions through mobile credit card readers. LocalRaces.com charges a processing fee for registrants and offers a suite of software solutions that cover various aspects of event management, including volunteer coordination, sponsorship, and vendor management. The platform hosts a vast network of local running and cycling events across the U.S., allowing athletes to manage their race itineraries, results, and training through web-based tools and mobile applications. Additionally, LocalRaces.com generates revenue from advertising and partnerships within the running shoe and apparel market, and plans to expand its offerings by opening its API for third-party development, further enhancing its reach and service capabilities.

Sparo

Grant in 2016
Sparo Labs is an award-winning startup company in St. Louis dedicated to breathing life into the asthma industry. The company flagship product, Wing, uses innovative technology to accurately measure lung function through a smartphone-connected, pocket-sized device. This empowers patients to better understand, track, and proactively manage their asthma so they can discover what most of us take for granted — a simple breath. The Wings also measures lung function with medical-grade accuracy and helps patients monitor their condition and manage medications, triggers, and symptoms. It also helps end the fear and uncertainty of asthma by empowering people to understand, track, and proactively control their condition. Sparo Labs was established in 2012 and is based in St. Louis, MO, USA.

EternoGen

Grant in 2016
EternoGen is a medical biotech company designing and manufacturing collagen scaffolds for soft tissue therapeutic applications. It is primarily a research and development company that utilizes expertise in clinical market evaluation, material science, and biological engineering to execute its clinical development model. The company was founded in 2009 and is headquartered in Columbia, Missouri.

FocalCast

Seed Round in 2016
FocalCast offers a range of interactive web-based market research platforms for global brands and marketing agencies. FocalCast was founded by Devin Turner and Charlie Beckwith in September 2013 and is based in St Louis, Missouri.

FinLocker

Seed Round in 2016
FinLocker, LLC is a financial technology company founded in 2014 and based in St. Louis, Missouri. It develops a consumer-enabled financial data platform that facilitates the loan process for mortgages and other financial products. The platform serves both businesses and consumers by streamlining loan transactions and enhancing the overall financial experience. For businesses, FinLocker provides tools that cut costs, reduce fraud, and mitigate risks while improving customer satisfaction and operational efficiency. For consumers, the platform simplifies the loan application process, minimizes paperwork, and enables better management of personal finances. Using consumer consent, FinLocker captures essential borrower data and employs intelligent analytics to offer tailored loan product recommendations based on individual financial profiles.

PayIt

Series A in 2016
PayIt, LLC is a technology company based in Kansas City, Missouri, that specializes in cloud-based solutions to modernize government payment systems. Established in 2013, PayIt provides a digital platform that enables state and local government agencies to enhance the payment experience for residents. Its services encompass various sectors, including property tax, utilities, courts, and public safety, facilitating a seamless and secure digital payment process across web and mobile interfaces. By integrating with existing back-office systems, PayIt creates a unified resident profile that streamlines interactions across different agencies and jurisdictions. The company serves over 100 million residents in North America and has received accolades for its innovative approach, including recognition from Fast Company and StateScoop.

Bonfyre

Funding Round in 2016
Bonfyre Inc. is an employee engagement platform founded in 2013 and based in Saint Louis, Missouri. The company focuses on transforming workplace culture by providing technology that enhances employee recognition, communication, feedback, and event management. Its mobile-first platform offers real-time communication tools such as announcements, targeted broadcasts, and pop surveys, which help organizations foster camaraderie, align their culture, and gather valuable HR insights. By modernizing employee communications, Bonfyre enables companies to build stronger relationships and increase engagement, ultimately promoting a collaborative and innovative work environment.

MedSocket

Seed Round in 2015
MedSocket offers a clinical decision support system aimed at enhancing the efficiency and quality of patient care. The company has developed a patented 1-Click Decision Support (1-CDS) system and a medical search engine known as 1-Search, both designed by clinicians to address their specific needs. These technologies facilitate quick and easy access to evidence-based information for busy healthcare providers, thereby aiming to improve healthcare decisions, reduce errors, and enhance patient outcomes. Successful pilots of these systems at the University of Missouri Health System have demonstrated their potential to decrease healthcare costs and improve the overall efficiency of patient consultations. Founded in 2012 by Dr. Karl Kochendorfer, who recognized the necessity for immediate information access in clinical settings, MedSocket combines expertise in business and information science to refine clinical decision-making processes.

MedSocket

Seed Round in 2015
MedSocket offers a clinical decision support system aimed at enhancing the efficiency and quality of patient care. The company has developed a patented 1-Click Decision Support (1-CDS) system and a medical search engine known as 1-Search, both designed by clinicians to address their specific needs. These technologies facilitate quick and easy access to evidence-based information for busy healthcare providers, thereby aiming to improve healthcare decisions, reduce errors, and enhance patient outcomes. Successful pilots of these systems at the University of Missouri Health System have demonstrated their potential to decrease healthcare costs and improve the overall efficiency of patient consultations. Founded in 2012 by Dr. Karl Kochendorfer, who recognized the necessity for immediate information access in clinical settings, MedSocket combines expertise in business and information science to refine clinical decision-making processes.

Orange EV

Seed Round in 2015
Orange EV LLC is a manufacturer of industrial electric vehicles, specifically Class 8 heavy-duty trucks. Founded in 2012 and headquartered in Riverside, Missouri, the company focuses on producing zero-emission vehicles that offer significant environmental, financial, and operational advantages. By eliminating diesel-related costs and emissions, Orange EV's trucks help reduce the carbon footprint of fleets while providing comparable power to traditional fuel-consuming vehicles. The company also offers a range of services, including vehicle charging, demonstration drives, on-site warranty support, and financing options, aimed at enhancing the efficiency and safety of fleet operations while contributing to a cleaner environment.

Euclises Pharmaceuticals

Venture Round in 2015
Euclises Pharmaceuticals, Inc. is engaged in the research, development, and commercialization of innovative medicines targeting inflammation and oncology. Founded in 2011 and headquartered in Saint Louis, Missouri, the company focuses on creating novel pain and cancer medications that promise enhanced safety profiles compared to current therapies. The firm is built on pioneering inventions by Dr. John Talley, a renowned medicinal chemist known for developing Celebrex among other approved drugs. Euclises aims to introduce new compounds that provide improved efficacy and safety, positioning itself as a leader in the pharmaceutical industry. The company operates from the BioGenerator Accelerator Labs, where it continues to advance its research initiatives.

GeneriCo

Venture Round in 2015
GeneriCo, LLC is a pharmaceutical company that specializes in the development and marketing of generic drugs. Founded in 2013 and headquartered in Saint Louis, Missouri, with additional offices in Bengaluru, Italy, and South Korea, GeneriCo focuses on niche generic pharmaceuticals that are often overlooked by larger competitors. The company targets foundational medicines in key therapeutic areas, including cardiovascular health, pain management, central nervous system disorders, oncology, and aging-related conditions. GeneriCo distinguishes itself through its expertise in complex formulations and embedded drug delivery technologies, addressing market needs that are typically neglected by mid-sized and large generic firms. The company's global reach enables it to serve a diverse customer base.

SanusEO

Pre Seed Round in 2015
SanusEO, LLC is a mobile health technology company based in St. Louis, Missouri, specializing in a text-based patient engagement platform (PEP) designed to enhance communication between patients and care teams. Founded in 2012, SanusEO's platform supports healthcare providers, chronic disease patients, and payers by delivering daily alerts and real-time data to care teams, facilitating both immediate and long-term intervention strategies. The platform is particularly effective for managing patients transitioning from hospital care and those newly diagnosed with chronic conditions. By utilizing mobile texting programs, SanusEO aims to modify patient behaviors related to medication adherence, vital monitoring, diet, physical activity, and overall communication with healthcare providers. The approach targets various chronic diseases, including diabetes and congestive heart failure, and offers multi-language capabilities to cater to diverse patient populations.

Covercress

Series A in 2015
CoverCress Inc. is a biotechnology company based in St. Louis, Missouri, focused on developing and commercializing field pennycress as an oilseed crop. Founded in 2013, the company aims to produce oil for industrial and renewable fuels, as well as meal for nutritious livestock feed. CoverCress specializes in crop breeding services that enhance soil cover during corn harvest and soybean planting, allowing farmers to maximize yields through sustainable agricultural practices. The company is dedicated to utilizing low-input methods to create a feedstock for low carbon intensity biofuels, contributing to more efficient and environmentally friendly agricultural solutions.

BenchmarkONE

Venture Round in 2015
BenchmarkONE develops sales and marketing automation software tailored for small and mid-sized businesses. The company offers an integrated platform that includes customer relationship management (CRM) tools and sales automation features, allowing users to monitor contacts' activities, track deals, manage communications, and segment their audience. Additionally, BenchmarkONE provides email marketing capabilities with a user-friendly drag-and-drop email builder and marketing automation tools designed to engage visitors, prioritize leads, and optimize campaign investments. Originally known as Hatchbuck, Inc., the company rebranded to BenchmarkONE in June 2020 and has been operational since 2010, with its headquarters in St. Louis, Missouri. As of September 2019, BenchmarkONE functions as a subsidiary of Benchmark Internet Group, LLC.

SynerZ Medical

Seed Round in 2015
SynerZ Medical, Inc. develops medical device for the treatment of obesity and type 2 diabetes. The company was incorporated in 2013 and is based in St. Louis, Missouri.

ImmunoPhotonics

Series A in 2015
ImmunoPhotonics, Inc. is a biotechnology company focused on developing innovative immunotherapy treatments for cancer, specifically targeting metastatic solid tumors. Founded in 2008 and located in Columbia, Missouri, the company has created a proprietary drug product designed to function as a minimally invasive therapeutic cancer vaccine. This product is administered through intratumoral injection following tumor ablation, leveraging tumor-associated neoantigens to stimulate a systemic anti-tumor immune response. By transforming the process of tumor ablation into a therapeutic approach, ImmunoPhotonics aims to enhance treatment options for patients with late-stage metastatic cancers. The company has also established a strategic partnership with Veterinary Cancer Therapeutics, LLC to further its mission in cancer treatment.

Kultevat

Venture Round in 2015
Kultevat, Inc. is a biotechnology company focused on the cultivation and processing of dandelion varieties to produce natural rubber. The company primarily works with TKS Dandelion, a domestic source of rubber in the United States, Canada, and Europe, and also extracts rubber from Russian Dandelion. Kultevat's offerings include latex and bulk rubber products used in a variety of applications such as gloves, medical devices, and automotive parts, as well as renewable food co-products and sugar feedstocks for biofuel production. Founded in 2013 and based in Portageville, Missouri, Kultevat aims to provide sustainable alternatives to synthetic rubber, contributing positively to agricultural markets and reducing environmental impact.

Euclises Pharmaceuticals

Series A in 2014
Euclises Pharmaceuticals, Inc. is engaged in the research, development, and commercialization of innovative medicines targeting inflammation and oncology. Founded in 2011 and headquartered in Saint Louis, Missouri, the company focuses on creating novel pain and cancer medications that promise enhanced safety profiles compared to current therapies. The firm is built on pioneering inventions by Dr. John Talley, a renowned medicinal chemist known for developing Celebrex among other approved drugs. Euclises aims to introduce new compounds that provide improved efficacy and safety, positioning itself as a leader in the pharmaceutical industry. The company operates from the BioGenerator Accelerator Labs, where it continues to advance its research initiatives.

Lumate

Seed Round in 2013
Lumate, LLC is a technology company that specializes in mobile advertising, providing a context-driven platform that enhances audience targeting for advertisers. Founded in 2008 and headquartered in Saint Louis, Missouri, Lumate offers a suite of products designed to optimize the mobile advertising experience. Key offerings include AdTrade, a bidding engine that analyzes data to improve contextual relevance, AdMotive, a self-service portal that allows advertisers to customize their reach, and DataWell, an API and SDK aimed at publishers and data providers for monetizing audience data. By integrating geo-location and real-time bidding technologies, Lumate addresses gaps in the mobile advertising supply chain, enabling advertisers and ad networks to effectively connect with their desired audiences.

Adarza BioSystems

Seed Round in 2013
Adarza BioSystems is an early-stage medical diagnostics company based in St. Louis, Missouri, founded in 2008. The company specializes in developing a rapid and label-free biological assay platform that measures clinical and point-of-care samples. This innovative platform employs diagnostic arrayed imaging reflectometry (AIR) to enable the simultaneous detection of hundreds of analytes from a single drop of fluid, allowing healthcare professionals to conduct sophisticated tests with high sensitivity and specificity. By significantly reducing the time required for testing, Adarza BioSystems aims to enhance diagnostic capabilities in various healthcare settings.

EternoGen

Series A in 2013
EternoGen is a medical biotech company designing and manufacturing collagen scaffolds for soft tissue therapeutic applications. It is primarily a research and development company that utilizes expertise in clinical market evaluation, material science, and biological engineering to execute its clinical development model. The company was founded in 2009 and is headquartered in Columbia, Missouri.

Traxxsson

Seed Round in 2013
Traxxsson is a biotechnology company that develops diagnostics for cancer using protein biomarkers. It uses a proprietary panel of biomarkers to identify at-risk patients who have questionable radiology images. It has three tests: PRO CancSure to identify prostate cancer patients in need of aggressive treatment, BRE CancSure to confirm the presence of breast cancer in women with positive mammograms, and LNG CancSure to confirm the presence of lung cancer in patients with positive low-density CAT scan results. The company was founded in 2009 and is based in St. Louis, Missouri.

Kypha

Seed Round in 2012
Kypha Inc. is a life sciences company focused on developing and commercializing in-vitro diagnostic biomarker tests for inflammation and autoimmune disorders. Based in St. Louis, Missouri, the company offers the COMP ACT System, which enhances the monitoring and treatment of various health conditions, including lupus, stroke, traumatic brain injury, preeclampsia, infection, kidney disease, and transplant rejection. Kypha aims to provide rapid and accurate assessments of inflammation levels, enabling healthcare professionals to make timely and informed clinical decisions. With a core team supported by scientific advisors and clinical collaborators, Kypha has successfully secured federal grants and raised private capital to advance its diagnostic products toward regulatory approval and market launch. The company's technology is designed for scalability, facilitating testing in diverse settings from home health to clinical laboratories, ultimately improving patient outcomes through timely intervention.

Bonfyre

Seed Round in 2012
Bonfyre Inc. is an employee engagement platform founded in 2013 and based in Saint Louis, Missouri. The company focuses on transforming workplace culture by providing technology that enhances employee recognition, communication, feedback, and event management. Its mobile-first platform offers real-time communication tools such as announcements, targeted broadcasts, and pop surveys, which help organizations foster camaraderie, align their culture, and gather valuable HR insights. By modernizing employee communications, Bonfyre enables companies to build stronger relationships and increase engagement, ultimately promoting a collaborative and innovative work environment.

Euphrates Vascular

Venture Round in 2010
Euphrates Vascular is a medical technology company based in St. Louis, Missouri, focused on developing innovative solutions for the treatment of stroke, heart disease, and other related conditions. The company's flagship product, the magnetically-enhanced diffusion (MED) system, employs advanced magnet-based technology to accelerate the dissolution of blood clots, offering a faster delivery of FDA-approved clot-busting medications compared to traditional methods. This technology aims to significantly reduce mortality rates associated with strokes and heart disease. In addition to the MED system, Euphrates Vascular offers MED MicroBeads, which facilitate the rapid delivery of selected therapeutic agents to blood clots, and a touch screen-operated MED Workstation for enhanced user interaction. Founded by physicists with extensive experience in medical technology, the company continues to attract interest from investors and media for its groundbreaking contributions to cardiovascular care.
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