Canaan X

Canaan X, established in 2014, is an early-stage venture capital fund based in San Francisco, California, managed by Canaan Partners. The fund invests in early-stage companies across the United States, Israel, and India, focusing on software, healthcare, and technology, media, and telecommunications (TMT) sectors. Canaan X typically invests between $1 million to $20 million per company, supporting entrepreneurs from the early stages through expansion.

Brent Ahrens

General Partner

Nandu Anilal

Vice President, East Coast

Richard Boyle

General Partner - West Coast

Laura Chau

General Partner - East Coast

Brendan Dickinson

General Partner - East Coast

Rayfe Gaspar-Asaoka

Partner - West Coast

Nina Kjellson

General Partner - West Coast

Ehud Levy

Co-Founder and General Partner, Canaan Partners Israel

Jared Newman

Vice President, East Coast

Julie Papanek

Partner

Guy Russo

General Partner - East Coast

Uwe Schoenbeck

Venture Partner

Hrach Simonian

General Partner - West Coast

Dana Warren

Venture Partner, East Coast

Bob Williams

Venture Partner - West Coast

Mark Mangiola

Venture Partner

Past deals in Growth Stage

Cynomi

Series B in 2025
Cynomi is a London-based company founded in 2021 that specializes in providing scalable virtual Chief Information Security Officer (vCISO) services through its AI-powered platform. The platform enables managed security service providers (MSSPs) and consulting firms to deliver comprehensive vCISO services without the need to expand their current resources. Cynomi's multi-tenant architecture automates the generation of essential vCISO deliverables, including risk and compliance assessments, customized security policies, actionable remediation plans, and task management tools. It conducts a thorough analysis of a company's cybersecurity posture, producing detailed and prioritized remediation strategies that are continuously updated. This approach facilitates optimal security and regulatory compliance for organizations, ensuring they remain protected in an evolving cyber landscape.

AttoTude

Series B in 2025
AttoTude is a technology company specializing in the development of advanced interconnect solutions for AI and hyperscale data centers. It aims to surpass the limitations of existing data networking systems by creating innovative technology that significantly boosts bandwidth, enhances reliability, and reduces power consumption and costs.

Nivoda

Series C in 2024
Nivoda Limited is a B2B online marketplace that facilitates the buying and selling of diamonds and jewelry. Founded in 2017 and headquartered in London, with an additional office in Hong Kong, Nivoda aims to streamline the global jewelry trade by offering a comprehensive solution for businesses. The platform enables users to efficiently browse a wide selection of diamonds and gemstones from verified suppliers, ensuring competitive pricing and reliable sourcing. By simplifying the procurement process, Nivoda helps jewelry businesses enhance their profitability and accelerate growth while avoiding the logistical challenges and extra costs associated with international purchases.

Halda Therapeutics

Series B in 2024
Halda Therapeutics is a research-stage drug discovery company dedicated to developing next-generation precision medicine. The company employs a unique therapeutic modality that serves as a platform for addressing various disease states. By focusing on the discovery of novel therapies that modify disease-causing pathways, Halda Therapeutics aims to enable healthcare providers to offer more targeted treatments for their patients. Through its innovative approach, the company seeks to advance the field of precision medicine and improve patient outcomes.

Autobahn Therapeutics

Series C in 2024
Autobahn Therapeutics, Inc. is a biotechnology company based in San Diego, California, focused on developing small molecule therapies for central nervous system (CNS) disorders. Founded in 2017 and originally named Llama Therapeutics, the company aims to address significant unmet medical needs in neuropsychiatry, neurodegeneration, and neuroinflammation. Autobahn's lead candidate, ABX-002, is a thyroid hormone receptor beta agonist being investigated as a potential adjunctive treatment for multiple sclerosis, adrenomyeloneuropathy, major depressive disorder, and bipolar disorder depression. The company employs a brain-targeting chemistry platform that allows for precise tuning of CNS exposure while pursuing validated clinical and biological targets, guided by biomarkers, to unlock new therapeutic opportunities.

Greywolf Therapeutics

Series B in 2024
Grey Wolf Therapeutics is a biotechnology company based in Oxford, United Kingdom, focused on developing innovative immunotherapies for oncology. Founded in 2017, the company aims to enhance the visibility of non-responsive tumors to the immune system by directly modifying tumor cells. Its approach involves targeting endoplasmic reticulum aminopeptidases (ERAP) 1 and 2 within the antigen presentation pathway, which increases the neoantigen repertoire on tumor cells. This strategy is designed to improve the effectiveness of immunotherapy in treating cancer. Grey Wolf collaborates with leading academic and commercial partners to advance its drug discovery initiatives and deliver clinical candidates against well-validated targets in the field of immuno-oncology.

Nivoda

Series B in 2024
Nivoda Limited is a B2B online marketplace that facilitates the buying and selling of diamonds and jewelry. Founded in 2017 and headquartered in London, with an additional office in Hong Kong, Nivoda aims to streamline the global jewelry trade by offering a comprehensive solution for businesses. The platform enables users to efficiently browse a wide selection of diamonds and gemstones from verified suppliers, ensuring competitive pricing and reliable sourcing. By simplifying the procurement process, Nivoda helps jewelry businesses enhance their profitability and accelerate growth while avoiding the logistical challenges and extra costs associated with international purchases.

Quantum Circuits

Venture Round in 2024
Quantum Circuits, Inc. is a New Haven, Connecticut-based company that develops, manufactures, and sells superconducting quantum computers. Founded in 2015 by Dr. Robert Schoelkopf, a leading figure in quantum science, the company focuses on creating full-stack quantum computing solutions that prioritize error correction to enhance scalability. Utilizing a dual-rail qubit design, Quantum Circuits aims to reduce the number of physical qubits needed for logical qubit operations by a factor of ten, thereby streamlining the path to fault-tolerant quantum computing. The company's innovative approach allows for efficient quantum computations, making it a significant player in the advancement of quantum technology and its applications in research and industry.

Qlaris Bio

Series B in 2024
Qlaris Bio is a clinical-stage biotechnology company based in Wellesley, Massachusetts, founded in 2017. The company specializes in developing innovative therapies for serious and debilitating ophthalmic diseases, with a focus on addressing episcleral venous pressure (EVP), a significant component of intraocular pressure (IOP). Qlaris Bio's lead therapy, QLS-101, aims to reduce IOP, thereby mitigating the risk of blindness in conditions such as Primary Open Angle Glaucoma and Normal Tension Glaucoma. The company also targets other high unmet need conditions related to disturbances in intraocular pressure, including a progressive pediatric rare disease with limited effective therapies.

Pathios Therapeutics

Series B in 2024
Pathios Therapeutics is an early-stage biotech company based in Oxford, United Kingdom, focused on developing therapies for autoimmune diseases and cancer. Founded in 2017, the company specializes in creating small molecule inhibitors that target the pH-sensing G protein-coupled receptor GPR65. These inhibitors are designed to counteract the immunosuppressive effects of immune cells, such as tumor-associated macrophages, which are influenced by the acidic environment often found in tumors. By leveraging a deep scientific approach and human genetic insights, Pathios Therapeutics aims to generate novel therapeutics for advanced solid tumors and other unmet medical needs.

Alterome Therapeutics

Series B in 2024
Alterome Therapeutics is a biotechnology company focused on precision oncology, specializing in the development of alteration-specific therapeutics aimed at treating cancer. By targeting high-value and validated oncogenic drivers, Alterome seeks to create innovative biopharmaceutical therapies that offer hope to individuals affected by cancer. The company's approach is centered on discovering and developing precise treatments that cater to the unique genetic alterations present in different cancer types, thereby enhancing the effectiveness of cancer therapies for healthcare providers and patients alike.

Lily AI

Series B in 2024
Lily AI is an innovative e-commerce product discovery platform based in Mountain View, California, that focuses on enhancing the sales performance of brands and retailers. The company specializes in integrating customer-centric product attributes into various facets of the e-commerce ecosystem, including site search engines and recommendation systems. By aligning brand messaging with customer intent, Lily AI improves on-site search, personalized product discovery, and demand prediction. This approach enables retailers, particularly in the fashion, home, and beauty sectors, to achieve significant increases in traffic, conversion rates, revenue, and brand loyalty.

Nocion Therapeutics

Series B in 2024
Nocion Therapeutics, Inc. is a biopharmaceutical company based in Cambridge, Massachusetts, established in 2017. It specializes in developing innovative therapies known as "nocions," which are designed to treat conditions resulting from neurogenic inflammation. These therapies selectively target activated nociceptors, the sensory neurons responsible for pain perception, by utilizing small molecule charged sodium channel blockers. This targeted approach aims to provide robust and sustained relief from serious conditions such as cough, itch, pain, and inflammation, addressing the limitations of traditional small molecule anesthetics.

AgomAb Therapeutics

Series C in 2023
AgomAb Therapeutics N.V., based in Gent, Belgium, specializes in the development of molecular therapies aimed at regenerating damaged tissues. The company focuses on creating agonistic monoclonal antibodies, known as agomAbs, which are designed to stimulate molecular and cellular repair mechanisms. These therapies have the potential to restore organ function in patients suffering from fibrotic, inflammatory, autoimmune, and degenerative diseases. AgomAb targets biologically validated pathways, including Transforming Growth Factor β and Hepatocyte Growth Factor, while employing specialized capabilities in organ-specific small molecules and high-affinity antibodies. The company boasts a diversified clinical pipeline addressing various fibrotic conditions and possesses comprehensive research and development expertise, alongside a strong track record in business development.

Acesion Pharma

Series B in 2023
Acesion Pharma ApS is a biotechnology company based in Copenhagen, Denmark, focused on developing medical treatments for atrial fibrillation (AF), the most prevalent type of cardiac arrhythmia. Founded in 2011, Acesion Pharma specializes in creating SK channel inhibitors that aim to provide safe and tolerable chronic treatments for AF. These drugs work by inhibiting specific ion channels in heart cells, which are crucial for generating the electrical signals that regulate the heart's rhythm. The company's goal is to offer effective solutions for preventing the recurrence of atrial fibrillation and maintaining normal heart rhythm, thereby improving the quality of life for patients affected by this condition.

Kepler

Series C in 2023
Kepler Communications Inc. is a Toronto-based satellite communications company focused on creating a robust in-space telecommunications network for connecting various space-borne assets. Established in 2015, the company designs, develops, and operates a constellation of Low-Earth Orbit (LEO) satellites that act as on-orbit cell towers, facilitating real-time connectivity for diverse applications. Kepler's offerings include PolarConnect, a communication solution for operations in extreme environments, and Global Data Service, which enables efficient transfer of large data files from remote locations to the internet. Additionally, the company is developing everywhereIOT, a low-power satellite service designed to connect Internet of Things devices globally. By addressing the challenge of intermittent connectivity for non-geostationary satellites, Kepler aims to enhance communication capabilities in industries such as maritime, natural resources, defense, and logistics. With two satellites already in orbit and plans for further expansion, Kepler is positioning itself at the forefront of space-based connectivity solutions.

Greywolf Therapeutics

Series B in 2023
Grey Wolf Therapeutics is a biotechnology company based in Oxford, United Kingdom, focused on developing innovative immunotherapies for oncology. Founded in 2017, the company aims to enhance the visibility of non-responsive tumors to the immune system by directly modifying tumor cells. Its approach involves targeting endoplasmic reticulum aminopeptidases (ERAP) 1 and 2 within the antigen presentation pathway, which increases the neoantigen repertoire on tumor cells. This strategy is designed to improve the effectiveness of immunotherapy in treating cancer. Grey Wolf collaborates with leading academic and commercial partners to advance its drug discovery initiatives and deliver clinical candidates against well-validated targets in the field of immuno-oncology.

WorkMotion

Series B in 2022
WorkMotion is a global HR platform founded in 2020 and headquartered in Berlin, Germany. The company specializes in facilitating the hiring and onboarding of employees internationally, allowing organizations to recruit and manage remote workers from various countries with ease. Its cloud-based workforce management platform streamlines the hiring process by enabling employers to consolidate global payroll accounting and manage freelancers without the need to establish legal entities in foreign markets. By providing a comprehensive solution for international employment, WorkMotion supports businesses in expanding their talent acquisition capabilities across borders.

Appsmith

Series B in 2022
Appsmith is a company that specializes in open-source low-code software aimed at facilitating the rapid development of custom internal applications. Founded in mid-2019, Appsmith's platform allows developers to create, deploy, and manage applications with a focus on enterprise-grade security and governance. The software simplifies the development of internal tools, streamlining operations, automating processes, and enabling seamless integration of various applications and data sources. With over 5 million downloads and a user base that includes more than 1,000 enterprises across over 100 countries, Appsmith has established itself as a significant player in the low-code application development space, empowering developers to enhance legacy applications and build efficient internal web apps.

Lily AI

Venture Round in 2022
Lily AI is an innovative e-commerce product discovery platform based in Mountain View, California, that focuses on enhancing the sales performance of brands and retailers. The company specializes in integrating customer-centric product attributes into various facets of the e-commerce ecosystem, including site search engines and recommendation systems. By aligning brand messaging with customer intent, Lily AI improves on-site search, personalized product discovery, and demand prediction. This approach enables retailers, particularly in the fashion, home, and beauty sectors, to achieve significant increases in traffic, conversion rates, revenue, and brand loyalty.

Dusty Robotics

Series B in 2022
Dusty Robotics, Inc. is a technology company that specializes in automated layout services for the construction industry. Founded in 2018 and headquartered in Mountain View, California, the company has developed the FieldPrinter, a robotic tool that translates digital building information modeling (BIM) designs into accurate, on-site layouts. By integrating BIM information directly onto construction-site floors, Dusty Robotics eliminates manual processes, thereby enhancing efficiency in the construction workflow. The company's innovative solutions serve a diverse clientele, including owners, general contractors, subcontractors, and builders, helping them to reduce labor and material waste and improve the overall design-build-operate lifecycle.

Lev

Series B in 2022
Lev Inc is a financial services company based in New York, founded in 2019, that specializes in lending and capital management solutions for commercial real estate transactions. The company has developed a technology platform that digitizes the process of finding and closing loans for property transactions. By leveraging machine learning and artificial intelligence, Lev's platform analyzes historical data and lender activity to identify optimal financing scenarios for each deal. It also facilitates communication by contacting and negotiating with lenders on behalf of clients, thereby streamlining the financing process and helping clients secure the most suitable financing for their projects.

BoostUp.ai

Series B in 2022
BoostUp.ai is a technology company based in Santa Clara, California, operating a sales intelligence platform designed to enhance revenue performance. Its platform analyzes macro and micro-level risks within sales forecasts, pipelines, deals, and seller behavior, transforming unstructured data into actionable insights. BoostUp.ai's Front Office Revenue Operations and Intelligence platform aims to improve forecasting accuracy, efficiency, predictability, and growth across the entire sales process. It automates processes, identifies risks and opportunities in the pipeline, and provides data-driven feedback to drive team efficiency and predictable revenue growth. The company serves leading organizations such as Teradata, Degreed, ContentSquare, Workato, Iterable, Branch, Udemy, and Windstream.

Hermeus

Series B in 2022
Hermeus Corporation, founded in 2018 and based in Atlanta, Georgia, is focused on developing hypersonic aircraft capable of flying at speeds exceeding Mach 5. These advanced jets significantly reduce travel times, allowing a flight from New York to London to take just 90 minutes instead of the typical seven hours. Hermeus aims to enhance the global transportation network by enabling businesses to operate efficiently without major changes to existing aviation infrastructure. The company's innovations not only decrease flight durations but also enhance safety for long-haul and business class air travel, facilitating improved connectivity between major global cities.

Instrumental

Series C in 2022
Instrumental, Inc. specializes in developing software solutions that enhance the efficiency of assembly lines, enabling them to operate autonomously while adapting to various parts and processes. Founded by former Apple engineers Anna-Katrina Shedletsky and Samuel Weiss, the company aims to reduce costs associated with scrap and rework by allowing manufacturers to identify and resolve issues on their assembly lines. Instrumental's technology has been deployed in multiple global assembly lines at leading manufacturers, helping to prevent delays in development schedules and start production at higher yields. In addition to its software offerings, Instrumental also provides services related to high-performance computing, data storage, and business continuity, catering to both commercial and government sectors. The firm is headquartered in Saint Paul, Minnesota, and has been operational since 1991.

Taptap Send

Series B in 2021
Taptap Send is a mobile application that facilitates instant money transfers for immigrants sending funds back to Africa at low costs. Launched in the summer of 2018, the platform has successfully processed hundreds of millions of dollars and serves hundreds of thousands of customers. It operates in seven European countries and enables payments to various countries, including Ivory Coast, Senegal, Mali, Ghana, Guinea, Cameroon, Bangladesh, Kenya, Madagascar, Zambia, Vietnam, and the Democratic Republic of the Congo, with plans for further expansion. Taptap Send simplifies the remittance process by allowing users to transfer money directly to mobile money wallets using just a debit card, eliminating the need for physical deposits and saving time for its clients.

Apex.AI

Series B in 2021
Apex.AI, Inc. is a software development company focused on creating solutions for autonomous mobility systems, particularly for self-driving vehicles. Founded in 2017 and headquartered in Palo Alto, California, the company offers Apex.OS, a software framework that simplifies the complexity of hardware and software integration through user-friendly, secure APIs. Additionally, Apex.AI provides Apex.Autonomy, a tool designed for safety-critical applications, and MARV.Automotive, a data management platform that facilitates the transfer of vehicle data to the cloud and enables advanced analytics and collaboration. The company's products leverage open-source technologies, allowing software developers to build reliable and efficient applications for autonomous vehicles.

Edge Impulse

Series B in 2021
Edge Impulse is a software platform focused on simplifying the development of machine learning models optimized for edge devices, where data is collected. The platform streamlines the entire process, encompassing data acquisition, signal processing, machine learning training, model testing, and deployment. It enables developers to create intelligent applications by facilitating the collection of real sensor data and processing it from raw inputs to neural networks. Edge Impulse's technology supports a wide range of devices, allowing for efficient operation on various hardware from microcontrollers to GPUs. By enhancing the accessibility and efficiency of embedded machine learning applications, Edge Impulse aims to promote positive societal change through advanced technology.

Sounding Board

Series B in 2021
Sounding Board is a technology company that specializes in leadership development. It offers a platform that provides personalized coaching for leaders and managers, connecting them with qualified coaches via phone, video, and chat. The platform creates tailored development plans, automates administration tasks, and offers data visualization tools to track progress and measure impact. Sounding Board serves global enterprises across 11 countries, with a strong focus on user experience and high-quality coaching. It was founded in 2016 and is headquartered in Foster City, California.

Reibus

Series B in 2021
Reibus is an online marketplace designed for the buying and selling of metals, specifically targeting industrial markets. The company connects businesses with a network of metal suppliers, facilitating seamless transactions and logistics for metal transportation. Its platform includes features such as anonymous buying, real-time leads for sellers, and transparent shipping options. By providing a proprietary search tool and a streamlined materials listing process, Reibus aims to enhance price performance, minimize time to market, and expand market reach, ultimately reducing sales and marketing-related expenses for its users.

Clutch

Series B in 2021
Clutch is a technology company focused on transforming the car buying experience by offering a fully online platform for purchasing high-quality certified vehicles. Through its website, customers can easily browse a diverse inventory of second-hand cars, select their preferred vehicle, and benefit from convenient at-home delivery. By eliminating traditional showrooms and commissioned salespeople, Clutch simplifies the purchasing process and provides competitive pricing. The company aims to enhance customer satisfaction by delivering a seamless and enjoyable car buying journey while also positively impacting the communities it serves.

CompStak

Series C in 2021
CompStak, Inc., founded in 2011 and headquartered in New York, operates an online platform that provides a comprehensive database of commercial lease comparables. Utilizing a crowd-sourced model, CompStak facilitates the exchange of detailed lease information, which includes tenant names, addresses, rental rates, square footage, landlord concessions, broker identities, and other pertinent data. This information is critical for real estate investors, brokers, asset managers, and appraisers as they conduct valuations and analyses of commercial properties. CompStak's platform serves various stakeholders in the real estate market, enabling informed decision-making in significant investments and property comparisons. Additionally, CompStak has established a strategic partnership with Knowledge Cubed to enhance its data offerings, further solidifying its position in the industry.

TrueFort

Series B in 2021
TrueFort Inc. is a cybersecurity company based in Weehawken, New Jersey, founded in 2015. It specializes in real-time application and cloud workload protection solutions, focusing on safeguarding critical applications and infrastructure. TrueFort's flagship product, Fortress, is a behavior-based security platform that employs advanced behavioral analysis, machine intelligence, and automation to create zero trust application environments. This platform addresses multiple security challenges by providing real-time application self-protection and enhanced visibility into enterprise applications. By leveraging existing agents and offering out-of-the-box analytics, TrueFort enables organizations to mitigate risks associated with excessive trust and cyber threats effectively.

Embroker

Series C in 2021
Embroker, Inc. is a digital insurance brokerage that specializes in providing insurance services to small and mid-sized businesses. Founded in 2015 and headquartered in San Francisco, with additional offices in Chicago, Boston, Denver, and New York, Embroker utilizes an online platform to streamline the process of purchasing, managing, and analyzing commercial insurance policies. The platform allows clients to automate the sharing, requesting, and tracking of proof of coverage, as well as monitor claims in real-time. Embroker offers a wide range of insurance products, including Commercial General Liability, property insurance, professional liability, and employee benefits, among others. The company also provides tools for peer comparison, enabling clients to benchmark their policies against industry standards. By combining technology with broker expertise, Embroker aims to enhance the efficiency and effectiveness of the $800 billion property and casualty insurance market, helping businesses save time and secure optimal coverage.

Kepler

Series B in 2021
Kepler Communications Inc. is a Toronto-based satellite communications company focused on creating a robust in-space telecommunications network for connecting various space-borne assets. Established in 2015, the company designs, develops, and operates a constellation of Low-Earth Orbit (LEO) satellites that act as on-orbit cell towers, facilitating real-time connectivity for diverse applications. Kepler's offerings include PolarConnect, a communication solution for operations in extreme environments, and Global Data Service, which enables efficient transfer of large data files from remote locations to the internet. Additionally, the company is developing everywhereIOT, a low-power satellite service designed to connect Internet of Things devices globally. By addressing the challenge of intermittent connectivity for non-geostationary satellites, Kepler aims to enhance communication capabilities in industries such as maritime, natural resources, defense, and logistics. With two satellites already in orbit and plans for further expansion, Kepler is positioning itself at the forefront of space-based connectivity solutions.

Archipelago

Series B in 2021
Archipelago Analytics, Inc., based in San Francisco, California, was incorporated in 2018 and specializes in utilizing artificial intelligence to enhance risk management for large commercial property owners. The company's platform digitizes risk data, facilitating improved insurance outcomes and overall resilience. By enabling the efficient movement of critical information through the insurance value chain—from clients to brokers and capacity providers—Archipelago aims to lower the total cost of risk for its users, ensuring they receive timely and relevant data to make informed decisions.

OncoResponse

Series C in 2021
OncoResponse Inc. is an immuno-oncology biotechnology company based in Houston, Texas, focused on developing innovative cancer therapies. The company utilizes a proprietary human antibody platform to identify fully human monoclonal antibodies targeting immuno-oncology pathways. By probing the adaptive immune systems of cancer patients who have shown exceptional responses to checkpoint inhibitors, OncoResponse aims to discover novel therapeutic antibodies. Its research emphasizes addressing immunosuppressive myeloid biology and enhancing immune activation, with the goal of transforming cold tumors into hot tumors that are more responsive to treatment. Through its advanced antibody pipeline, OncoResponse is dedicated to providing effective solutions for cancer treatment.

Tyra Biosciences

Series B in 2021
Tyra Biosciences, Inc. is a clinical-stage biotechnology company based in Carlsbad, California, dedicated to developing precision oncology therapies targeted at overcoming drug resistance in cancer treatment. Founded in 2018, the company utilizes its proprietary SNÅP platform to facilitate rapid and precise drug design by generating iterative molecular snapshots. This innovative approach allows Tyra to create next-generation therapies specifically aimed at addressing acquired resistance in tumors. The company's primary focus is on developing selective inhibitors of the Fibroblast Growth Factor Receptor (FGFR) family, which are implicated in approximately 7% of all cancers. Tyra's lead product candidate, TYRA-300, is designed to selectively inhibit FGFR3, initially targeting patients with metastatic urothelial carcinoma of the bladder and urinary tract.

Axis Security

Series C in 2021
Axis Security Inc. is a cybersecurity company founded in 2018 and based in Palo Alto, California. It specializes in Zero Trust Network Access solutions, providing a cloud security platform that ensures secure remote access to applications. The company's technology focuses on application isolation and employs a context-aware approach to security, evaluating multiple factors to ensure that only authorized users can access specific resources within a network. This business-centric strategy allows organizations to maintain control over sensitive information and manage access for employees, partners, and other stakeholders effectively.

Day One Biopharmaceuticals

Series B in 2021
Day One Biopharmaceuticals is a clinical-stage biotechnology company dedicated to developing targeted cancer therapies for patients of all ages, with a particular emphasis on pediatric patients who have historically been underserved in cancer treatment advancements. The company is committed to addressing the unique needs of children and adults facing cancer by creating therapies that are informed by the biology of childhood cancers. Day One Biopharmaceuticals aims to bring promising treatments rapidly to market, focusing on those that can benefit both younger and older patients. The company's lead product candidate, DAY101, is an oral, brain-penetrant pan-RAF kinase inhibitor designed to target genetically defined cancers. By licensing and acquiring innovative products from research institutions and other biopharmaceutical companies, Day One Biopharmaceuticals seeks to provide effective treatment options for families confronted with the challenges of a cancer diagnosis.

Vivace Therapeutics

Series C in 2020
Vivace Therapeutics, Inc. is a biotechnology company focused on the discovery and development of small molecule therapies aimed at treating cancer. Founded in 2014 and located in the San Francisco Bay Area, the company specializes in targeting the Hippo pathway, which plays a critical role in regulating tissue regeneration and organ size. Vivace Therapeutics employs an innovative approach by leveraging research from leading academic institutions to develop novel therapeutics that can be used independently or in combination with existing treatments. The company is committed to advancing promising drug candidates and therapeutic technologies to address the unmet needs of cancer patients, driven by a mission to improve patient outcomes and quality of life.

Dragos

Series C in 2020
Dragos is an industrial cybersecurity company specializing in protecting critical infrastructure worldwide. It develops software that provides real-time visibility into Industrial Control Systems (ICS) and Operational Technology (OT) networks, enabling early detection of threats and proactive mitigation strategies. The company's solutions are optimized for emerging technologies like the Industrial Internet of Things (IIoT), serving clients across power and water utilities, energy, and manufacturing sectors to enhance their overall security posture.

Vineti

Series C in 2020
Vineti, Inc. is a technology company focused on advancing the development and delivery of personalized therapies, particularly in the realm of cell and gene treatments for serious conditions like cancer. Founded in 2016 and headquartered in San Francisco, California, Vineti offers a cloud-based platform known as the Personalized Therapy Management (PTM) platform. This platform integrates various aspects of the therapeutic supply chain, including operations, manufacturing, quality assurance, and regulatory compliance, to streamline and automate processes. It addresses critical challenges faced by patients, healthcare providers, pharmaceutical companies, and regulatory bodies in the commercialization of personalized medicine. By enhancing supply chain orchestration and ensuring compliance with regulatory standards, Vineti aims to expand patient access to innovative therapies. The company also maintains regional offices in Bethesda, Maryland, and Yerevan, Armenia.

Axis Security

Series B in 2020
Axis Security Inc. is a cybersecurity company founded in 2018 and based in Palo Alto, California. It specializes in Zero Trust Network Access solutions, providing a cloud security platform that ensures secure remote access to applications. The company's technology focuses on application isolation and employs a context-aware approach to security, evaluating multiple factors to ensure that only authorized users can access specific resources within a network. This business-centric strategy allows organizations to maintain control over sensitive information and manage access for employees, partners, and other stakeholders effectively.

Papa

Series B in 2020
Papa, Inc. operates an online platform designed to connect college students with senior citizens, facilitating various services to assist older adults in maintaining their independence and well-being. Founded in 2016 and based in Miami, Florida, the platform enables college and nursing students to provide companionship and assistance in areas such as transportation, house chores, technology lessons, grocery shopping, and caregiving. By connecting vetted companions with older adults, Papa aims to enhance social connections and support for seniors, allowing them to live securely and happily at home.

nTopology

Series C in 2020
nTopology, Inc. is an engineering software company founded in 2013 and headquartered in New York, New York. The company specializes in developing design software and tools aimed at optimizing manufacturing processes. Its flagship platform, nTopology, empowers engineers to create lightweight and optimized parts that meet specific functional requirements. The software includes features such as Lightweighting, Architected Materials, Topology Optimization, Additive Manufacturing, and Design Analysis, facilitating the integration of geometry and simulation data into manufacturing-ready models. By streamlining workflows and enhancing team collaboration, nTopology serves a diverse range of industries, including aerospace and defense, medical, automotive, consumer products, and education.

Instrumental

Series B in 2020
Instrumental, Inc. specializes in developing software solutions that enhance the efficiency of assembly lines, enabling them to operate autonomously while adapting to various parts and processes. Founded by former Apple engineers Anna-Katrina Shedletsky and Samuel Weiss, the company aims to reduce costs associated with scrap and rework by allowing manufacturers to identify and resolve issues on their assembly lines. Instrumental's technology has been deployed in multiple global assembly lines at leading manufacturers, helping to prevent delays in development schedules and start production at higher yields. In addition to its software offerings, Instrumental also provides services related to high-performance computing, data storage, and business continuity, catering to both commercial and government sectors. The firm is headquartered in Saint Paul, Minnesota, and has been operational since 1991.

Mynd

Series C in 2020
Mynd is a technology-driven property management company specializing in single-family rental properties. It offers a suite of services, including property marketing, tenant screening, rent collection, maintenance, and accounting, to help investment property owners efficiently manage their assets and maximize returns. The company leverages technology and data analytics to enhance property performance, ensure timely communication, and provide property owners with real-time information and financial reports via its digital platforms.

READY Robotics

Series B in 2020
READY Robotics Corp., established in 2016, is headquartered in Columbus, Ohio. The company specializes in developing ForgeOS, an industrial operating system designed to simplify robotics and automation deployment and management. ForgeOS leverages patented technology and low-code apps, enabling manufacturers to automate high-mix/low-volume production efficiently. READY Robotics' platform connects various robotic devices and thousands of industrial automation tools via a cloud computing unit, allowing operators to control and program them collectively with minimal training.

Ladder

Series C in 2020
Ladder is a digital life insurance company established in 2015, headquartered in Palo Alto, California. It provides flexible term coverage up to $8 million across all U.S. states, offering savings of up to 40% compared to traditional policies. Ladder's platform streamlines the application process using real-time underwriting and an all-digital architecture, making life insurance more accessible and affordable for consumers without requiring commissioned sales agents or in-person visits.

Vineti

Series C in 2020
Vineti, Inc. is a technology company focused on advancing the development and delivery of personalized therapies, particularly in the realm of cell and gene treatments for serious conditions like cancer. Founded in 2016 and headquartered in San Francisco, California, Vineti offers a cloud-based platform known as the Personalized Therapy Management (PTM) platform. This platform integrates various aspects of the therapeutic supply chain, including operations, manufacturing, quality assurance, and regulatory compliance, to streamline and automate processes. It addresses critical challenges faced by patients, healthcare providers, pharmaceutical companies, and regulatory bodies in the commercialization of personalized medicine. By enhancing supply chain orchestration and ensuring compliance with regulatory standards, Vineti aims to expand patient access to innovative therapies. The company also maintains regional offices in Bethesda, Maryland, and Yerevan, Armenia.

Berkshire Grey

Series B in 2020
Berkshire Grey, Inc. is a technology company specializing in the development of artificial intelligence-driven robotic and automated material handling systems. Founded in 2013 and based in Lexington, Massachusetts, the company focuses on automating tasks traditionally performed by humans in commercial settings, enhancing efficiency in fulfillment, supply chain, and logistics operations. Its offerings include a range of robotic solutions, such as autonomous picking and sorting systems, mobile robotic units, and dynamic parcel sortation technologies. Additionally, Berkshire Grey provides electromechanical solutions that incorporate vision systems and advanced scanning technologies. By leveraging AI, computer vision, and machine learning, the company's systems enable clients to achieve higher accuracy and throughput speeds while managing diverse product assortments. The majority of its revenue is generated from North America, positioning Berkshire Grey as a significant player in the automation landscape.

Capella Space

Series B in 2019
Capella Space Corp. is a San Francisco-based company that manufactures and operates a constellation of commercial radar satellites, providing high-resolution synthetic aperture radar (SAR) imagery with a resolution of 50 centimeters. Founded in 2016, the company delivers on-demand Earth observation services that enable continuous global coverage, regardless of weather conditions or time of day. Capella's satellite technology is utilized across various industries for applications such as maritime domain awareness, urban planning, disaster response, and monitoring economic activities. By offering timely and flexible information, Capella Space aims to enhance decision-making in commerce, conservation, and security, ultimately contributing to improved outcomes in infrastructure monitoring, agriculture, and disaster recovery efforts.

Astra

Series C in 2019
Astra Space, Inc. is a technology company based in Alameda, California, that specializes in designing and building rockets for satellite delivery and launch services. Founded in 2004 and originally known as Ventions LLC, the company rebranded in 2016 and aims to provide accessible and affordable access to space. Astra offers online reservations for payload deliveries to both sun-synchronous and low inclination orbits, with a focus on dedicated launch services for payloads ranging from 50 kg to 150 kg. The business is divided into two segments: Launch Services, which provides rapid global launch capabilities, and Space Products, which includes the development of space products tailored to customer needs for successful satellite launches. Astra operates test facilities to support its operations and is committed to facilitating frequent access to space for satellite operators and governments.

PerimeterX

Series C in 2019
PerimeterX, Inc. is a cybersecurity company that specializes in developing solutions to prevent automated attacks and malicious web behavior. Founded in 2014 and headquartered in San Mateo, California, with additional locations in London, Miami, and a subsidiary in Tel Aviv, the company offers a suite of products aimed at protecting web infrastructure. Its flagship solutions, known as PerimeterX Bot Defender, provide real-time defenses against various types of bot attacks, including those targeting websites, mobile applications, and APIs. By leveraging behavioral analytics and advanced threat detection techniques, PerimeterX helps organizations in sectors such as e-commerce, travel, and media safeguard their digital assets from account abuse, web scraping, and marketing fraud. The company's innovative approach has garnered recognition, including being listed among the top cybersecurity startups and promising artificial intelligence firms.

ScaleFactor

Series C in 2019
ScaleFactor, Inc. is a technology company that provides a comprehensive suite of accounting and finance solutions designed to streamline business operations. Founded in 2014 and headquartered in Austin, Texas, ScaleFactor offers software that automates bookkeeping, financial analysis, and compliance services, allowing businesses to focus on growth and management. The company's platform utilizes machine learning to process and categorize financial transactions in real-time, delivering actionable insights to business owners and managers. In addition to its core accounting services, ScaleFactor also provides IT integration, HR and payroll support, and CFO advisory services, catering to a diverse range of industries including professional services, retail, and technology. ScaleFactor has additional offices in Denver, Coquitlam, New York, and Santa Monica, reflecting its commitment to serving a broad client base.

MindTickle

Series C in 2019
MindTickle is a global, privately-held company that specializes in providing a data-driven sales readiness platform aimed at enhancing the effectiveness of customer-facing teams. Headquartered in San Francisco, California, and Pune, India, MindTickle's platform is utilized by sales teams across various industries to bridge knowledge and skill gaps through automated training paths, adaptive learning, and virtual coaching tools. The company's solution incorporates on-demand online training, bite-sized mobile updates, gamification, and role-play, enabling enterprises to track onboarding progress and certify readiness. By leveraging MindTickle, organizations can improve sales performance, achieve larger deal sizes, increase win rates, and shorten sales cycles, ultimately driving growth and maximizing business impact.

nTopology

Series B in 2019
nTopology, Inc. is an engineering software company founded in 2013 and headquartered in New York, New York. The company specializes in developing design software and tools aimed at optimizing manufacturing processes. Its flagship platform, nTopology, empowers engineers to create lightweight and optimized parts that meet specific functional requirements. The software includes features such as Lightweighting, Architected Materials, Topology Optimization, Additive Manufacturing, and Design Analysis, facilitating the integration of geometry and simulation data into manufacturing-ready models. By streamlining workflows and enhancing team collaboration, nTopology serves a diverse range of industries, including aerospace and defense, medical, automotive, consumer products, and education.

CompStak

Series B in 2019
CompStak, Inc., founded in 2011 and headquartered in New York, operates an online platform that provides a comprehensive database of commercial lease comparables. Utilizing a crowd-sourced model, CompStak facilitates the exchange of detailed lease information, which includes tenant names, addresses, rental rates, square footage, landlord concessions, broker identities, and other pertinent data. This information is critical for real estate investors, brokers, asset managers, and appraisers as they conduct valuations and analyses of commercial properties. CompStak's platform serves various stakeholders in the real estate market, enabling informed decision-making in significant investments and property comparisons. Additionally, CompStak has established a strategic partnership with Knowledge Cubed to enhance its data offerings, further solidifying its position in the industry.

Gen.G esports

Series B in 2019
Gen.G esports is a prominent professional esports organization founded in 2017, with its headquarters in Seoul, South Korea, and additional offices in Los Angeles and Shanghai. The organization is known for bridging the esports markets in the United States and Asia, operating top teams in renowned games like Overwatch and League of Legends, and featuring a celebrated all-female Fortnite team. Gen.G has achieved significant recognition, including being ranked among the world's most valuable esports companies. Its teams have won seven global championships, reflecting their competitive prowess. Beyond team management, Gen.G offers a range of services such as coaching, training, and business development, while also creating platforms for global brands to engage with gaming fans. The company is committed to fostering inclusivity in esports through initiatives like #TeamBumble and the Gen.G Elite Esports Academy, which integrates academic programs with esports training. Gen.G's mission emphasizes leveraging the power of gaming to empower both fans and athletes in their pursuits, establishing it as a leader in the evolving landscape of sports entertainment.

Roman

Series B in 2019
Roman is a men's health company that offers online diagnosis and discreet shipping of safe erectile dysfunctional medication. The company was launched in 2017 as a vertical of Ro, a healthcare technology company.

JOOR

Series C in 2019
JOOR, Inc. is an online global fashion marketplace that facilitates wholesale buying by connecting brands and retailers through a digital platform. Founded in 2010 and headquartered in New York, with additional offices in cities such as Los Angeles, London, Milan, Paris, Sydney, and Melbourne, JOOR aims to enhance the wholesale purchasing process. The platform streamlines operations by eliminating manual, error-prone tasks, thereby allowing brands and retailers to focus on increasing revenue, reducing costs, and enhancing customer experiences. Additionally, JOOR leverages data analytics to enable users to monitor performance effectively. Through its innovative approach, JOOR serves as a vital resource in the retail industry, supporting businesses in navigating their wholesale transactions more efficiently.

PerimeterX

Series C in 2019
PerimeterX, Inc. is a cybersecurity company that specializes in developing solutions to prevent automated attacks and malicious web behavior. Founded in 2014 and headquartered in San Mateo, California, with additional locations in London, Miami, and a subsidiary in Tel Aviv, the company offers a suite of products aimed at protecting web infrastructure. Its flagship solutions, known as PerimeterX Bot Defender, provide real-time defenses against various types of bot attacks, including those targeting websites, mobile applications, and APIs. By leveraging behavioral analytics and advanced threat detection techniques, PerimeterX helps organizations in sectors such as e-commerce, travel, and media safeguard their digital assets from account abuse, web scraping, and marketing fraud. The company's innovative approach has garnered recognition, including being listed among the top cybersecurity startups and promising artificial intelligence firms.

Komprise

Series C in 2019
Komprise, Inc. is a data management software company founded in 2014 and headquartered in Campbell, California. It specializes in intelligent data-aware management solutions that enable organizations to store, organize, and analyze both on-premise and cloud-based data. The company's platform allows users to easily analyze and mobilize file and object data across multiple cloud environments, providing flexibility without vendor lock-in. Komprise's software employs data growth analytics to identify and manage both frequently accessed (hot) and infrequently accessed (cold) data, ensuring that unstructured data is moved to appropriate secondary storage based on criteria such as age and usage. This comprehensive approach facilitates efficient data lifecycle management, including replication, archiving, and migration.

Contentsquare

Series C in 2019
ContentSquare is a digital experience insights optimization platform that helps businesses analyze customer behavior through vast amounts of anonymous web, mobile, and app interactions, adhering to data privacy regulations such as the EU GDPR and California CCPA. By integrating diverse data sets, including content, user experience, product offerings, pricing, acquisition channels, and technical performance, the platform generates insights and AI-driven recommendations to enhance digital performance throughout the customer journey. Its solutions enable clients to better understand user interactions, measure content effectiveness, and clarify consumer intentions, ultimately leading to increased revenue and engagement while reducing operational costs. ContentSquare serves over 700 enterprise clients, including notable brands like American Express, Best Buy, and LVMH.

Kustomer

Series C in 2019
Kustomer, Inc. is a customer service software company that specializes in developing a customer relationship management (CRM) platform designed to enhance enterprise customer service experiences. Founded in 2015 and headquartered in New York, with an additional office in Durham, North Carolina, Kustomer's platform consolidates data from various sources, allowing businesses to manage inquiries and customer relationships effectively. It provides a comprehensive view of customer interactions, including buying history and previous help desk conversations, enabling agents to address customer queries and issues efficiently. Kustomer serves a range of notable brands, helping them deliver exceptional service and support through a unified timeline view, thereby streamlining communication and improving customer satisfaction.

ScaleFactor

Series B in 2019
ScaleFactor, Inc. is a technology company that provides a comprehensive suite of accounting and finance solutions designed to streamline business operations. Founded in 2014 and headquartered in Austin, Texas, ScaleFactor offers software that automates bookkeeping, financial analysis, and compliance services, allowing businesses to focus on growth and management. The company's platform utilizes machine learning to process and categorize financial transactions in real-time, delivering actionable insights to business owners and managers. In addition to its core accounting services, ScaleFactor also provides IT integration, HR and payroll support, and CFO advisory services, catering to a diverse range of industries including professional services, retail, and technology. ScaleFactor has additional offices in Denver, Coquitlam, New York, and Santa Monica, reflecting its commitment to serving a broad client base.

Bellhop

Series C in 2018
Bellhops, Inc. is a technology-driven moving services company based in Chattanooga, Tennessee, founded in 2013. It specializes in providing on-demand truck and trailer loading and unloading services, as well as heavy lifting assistance for small to medium-sized moves. The company connects athletic students with individuals and businesses in need of moving help through its user-friendly online platform and applications. Bellhops has established itself as a significant player in the moving industry, operating in 55 cities across the United States and focusing on delivering superior customer experiences at competitive prices. Its innovative model combines a dedicated team of movers with a transparent review system, allowing customers to manage their moving process with ease and efficiency.

Embroker

Series B in 2018
Embroker, Inc. is a digital insurance brokerage that specializes in providing insurance services to small and mid-sized businesses. Founded in 2015 and headquartered in San Francisco, with additional offices in Chicago, Boston, Denver, and New York, Embroker utilizes an online platform to streamline the process of purchasing, managing, and analyzing commercial insurance policies. The platform allows clients to automate the sharing, requesting, and tracking of proof of coverage, as well as monitor claims in real-time. Embroker offers a wide range of insurance products, including Commercial General Liability, property insurance, professional liability, and employee benefits, among others. The company also provides tools for peer comparison, enabling clients to benchmark their policies against industry standards. By combining technology with broker expertise, Embroker aims to enhance the efficiency and effectiveness of the $800 billion property and casualty insurance market, helping businesses save time and secure optimal coverage.

Dragos

Series B in 2018
Dragos is an industrial cybersecurity company specializing in protecting critical infrastructure worldwide. It develops software that provides real-time visibility into Industrial Control Systems (ICS) and Operational Technology (OT) networks, enabling early detection of threats and proactive mitigation strategies. The company's solutions are optimized for emerging technologies like the Industrial Internet of Things (IIoT), serving clients across power and water utilities, energy, and manufacturing sectors to enhance their overall security posture.

OncoResponse

Series B in 2018
OncoResponse Inc. is an immuno-oncology biotechnology company based in Houston, Texas, focused on developing innovative cancer therapies. The company utilizes a proprietary human antibody platform to identify fully human monoclonal antibodies targeting immuno-oncology pathways. By probing the adaptive immune systems of cancer patients who have shown exceptional responses to checkpoint inhibitors, OncoResponse aims to discover novel therapeutic antibodies. Its research emphasizes addressing immunosuppressive myeloid biology and enhancing immune activation, with the goal of transforming cold tumors into hot tumors that are more responsive to treatment. Through its advanced antibody pipeline, OncoResponse is dedicated to providing effective solutions for cancer treatment.

Cargomatic

Series B in 2018
Cargomatic, Inc. is a technology-driven transportation platform that connects shippers with pre-screened carriers in real-time, primarily serving the short-haul and drayage trucking markets. Founded in 2013 and headquartered in Venice, California, Cargomatic facilitates an on-demand network for local truck availability, allowing shippers to submit loads and quickly find nearby trucks to meet their logistics needs. Since its launch in early 2014, the company has successfully supported tens of thousands of deliveries across California, Chicago, and metropolitan New York. By streamlining communication and reducing the reliance on traditional booking methods, Cargomatic enhances service levels, improves pick-up times and delivery rates, and enables customers to manage their outsourced transportation vendors more effectively through a single platform.

Antiva Biosciences

Series C in 2018
Antiva Biosciences, Inc. is a biopharmaceutical company based in South San Francisco, California, focused on developing antiviral therapies for human papillomavirus (HPV) infections. Established in 2012, the company aims to prevent cancer by treating precancerous lesions associated with HPV. Antiva's innovative approach includes localized therapeutics and small molecule antivirals that target HPV and other viral infections. The company is currently conducting clinical trials for high-grade anal intraepithelial neoplasias and high-grade cervical intraepithelial neoplasias. Through its medicinal chemistry platform, Antiva strives to enhance health outcomes for patients affected by HPV-related diseases and other viral infections.

Kustomer

Series B in 2018
Kustomer, Inc. is a customer service software company that specializes in developing a customer relationship management (CRM) platform designed to enhance enterprise customer service experiences. Founded in 2015 and headquartered in New York, with an additional office in Durham, North Carolina, Kustomer's platform consolidates data from various sources, allowing businesses to manage inquiries and customer relationships effectively. It provides a comprehensive view of customer interactions, including buying history and previous help desk conversations, enabling agents to address customer queries and issues efficiently. Kustomer serves a range of notable brands, helping them deliver exceptional service and support through a unified timeline view, thereby streamlining communication and improving customer satisfaction.

PACT Pharma

Series B in 2018
PACT Pharma, Inc. is a biotechnology company focused on developing personalized cell-based therapies for cancer treatment. The company specializes in neoantigen-specific adoptive T-cell therapies aimed at solid tumors. Its innovative platform utilizes bioinformatics to analyze patients' tumor and normal DNA and RNA, identifying candidate neoantigen peptides that stimulate robust antitumor T-cell responses. By pinpointing neo-epitopes unique to each patient's cancer, PACT Pharma enables the engineering of autologous T cells that specifically target and eradicate tumors expressing these neo-antigens. Founded in 2016 and headquartered in South San Francisco, California, PACT Pharma is dedicated to advancing personalized medicine in oncology.

Mynd

Series B in 2018
Mynd is a technology-driven property management company specializing in single-family rental properties. It offers a suite of services, including property marketing, tenant screening, rent collection, maintenance, and accounting, to help investment property owners efficiently manage their assets and maximize returns. The company leverages technology and data analytics to enhance property performance, ensure timely communication, and provide property owners with real-time information and financial reports via its digital platforms.

Rocketrip

Series C in 2018
Rocketrip, Inc. is a travel management platform founded in 2013 and based in New York, New York. The company focuses on enabling employees to make cost-effective travel decisions while earning rewards for saving on expenses. Its platform provides real-time insights into reasonable travel spending, allowing users to compare costs and choose lower-priced options for flights, cars, and hotels without disrupting their online booking process. By establishing a custom-calibrated budget known as the Price to Beat, Rocketrip incentivizes employees to select economical travel arrangements, thereby promoting a culture of cost savings within organizations. The platform is utilized by several enterprise brands, demonstrating its effectiveness in the corporate travel sector. As of September 2020, Rocketrip operates as a subsidiary of Mondee Holdings Inc.

Vineti

Series B in 2018
Vineti, Inc. is a technology company focused on advancing the development and delivery of personalized therapies, particularly in the realm of cell and gene treatments for serious conditions like cancer. Founded in 2016 and headquartered in San Francisco, California, Vineti offers a cloud-based platform known as the Personalized Therapy Management (PTM) platform. This platform integrates various aspects of the therapeutic supply chain, including operations, manufacturing, quality assurance, and regulatory compliance, to streamline and automate processes. It addresses critical challenges faced by patients, healthcare providers, pharmaceutical companies, and regulatory bodies in the commercialization of personalized medicine. By enhancing supply chain orchestration and ensuring compliance with regulatory standards, Vineti aims to expand patient access to innovative therapies. The company also maintains regional offices in Bethesda, Maryland, and Yerevan, Armenia.

Arvinas

Series C in 2018
Arvinas, Inc. is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, that specializes in the discovery, development, and commercialization of innovative therapies aimed at degrading disease-causing proteins. The company's lead product candidates include ARV-110, a proteolysis targeting chimera (PROTAC) currently in phase I clinical trials for metastatic castration-resistant prostate cancer, and ARV-471, which targets the estrogen receptor for patients with metastatic ER-positive/HER2-negative breast cancer. In addition to these, Arvinas is developing various other PROTACs aimed at degrading clinically relevant androgen receptor mutations and treatments for neurodegenerative diseases, including tauopathies. The company has established collaborations with prominent pharmaceutical firms such as Pfizer Inc., Genentech, and Bayer AG, enhancing its research capabilities and reach within the biopharmaceutical landscape. Founded in 2015, Arvinas aims to improve patient outcomes by eliminating harmful proteins from the body through its proprietary technology.

IDEAYA Biosciences

Series B in 2018
IDEAYA Biosciences, Inc., established in 2015 and headquartered in South San Francisco, California, specializes in oncology-focused precision medicine. The company discovers and develops targeted therapeutics for patient populations selected through molecular diagnostics. Its lead product candidate, IDE196, is a protein kinase C inhibitor currently in Phase 1/2 clinical trials for genetically-defined cancers with GNAQ or GNA11 gene mutations. IDEAYA's preclinical pipeline includes programs targeting MAT2A, Pol-theta, PARG, and WRN in various solid tumors. The company collaborates with institutions like Cancer Research UK and Pfizer Inc., and has partnerships with industry leaders such as GlaxoSmithKline plc.

Imanis Data

Series B in 2018
Imanis Data is a San Jose-based company that specializes in subscription-based data availability management solutions for enterprise-scale environments. Founded in 2012 and formerly known as Talena, the company offers two primary products: FastFind, a metadata catalog that simplifies Big Data application management across various platforms, and Imanis Data 3.0, a backup and recovery platform designed to detect ransomware attacks early and prevent accidental data loss. These solutions are architected for petabyte-scale datasets and leverage machine learning to minimize risk and reduce costs. As of May 2019, Imanis Data operates as a subsidiary of Cohesity, Inc.

Contentsquare

Series B in 2018
ContentSquare is a digital experience insights optimization platform that helps businesses analyze customer behavior through vast amounts of anonymous web, mobile, and app interactions, adhering to data privacy regulations such as the EU GDPR and California CCPA. By integrating diverse data sets, including content, user experience, product offerings, pricing, acquisition channels, and technical performance, the platform generates insights and AI-driven recommendations to enhance digital performance throughout the customer journey. Its solutions enable clients to better understand user interactions, measure content effectiveness, and clarify consumer intentions, ultimately leading to increased revenue and engagement while reducing operational costs. ContentSquare serves over 700 enterprise clients, including notable brands like American Express, Best Buy, and LVMH.

Apartment List

Series C in 2018
Apartment List, Inc., established in 2008 and headquartered in San Francisco, operates an online rental marketplace connecting renters and landlords across the United States. Its platform streamlines the housing search by offering personalized, curated listings based on users' preferences, ensuring a simple, enjoyable, and transparent process.

Ladder

Series B in 2018
Ladder is a digital life insurance company established in 2015, headquartered in Palo Alto, California. It provides flexible term coverage up to $8 million across all U.S. states, offering savings of up to 40% compared to traditional policies. Ladder's platform streamlines the application process using real-time underwriting and an all-digital architecture, making life insurance more accessible and affordable for consumers without requiring commissioned sales agents or in-person visits.

MindTickle

Series B in 2017
MindTickle is a global, privately-held company that specializes in providing a data-driven sales readiness platform aimed at enhancing the effectiveness of customer-facing teams. Headquartered in San Francisco, California, and Pune, India, MindTickle's platform is utilized by sales teams across various industries to bridge knowledge and skill gaps through automated training paths, adaptive learning, and virtual coaching tools. The company's solution incorporates on-demand online training, bite-sized mobile updates, gamification, and role-play, enabling enterprises to track onboarding progress and certify readiness. By leveraging MindTickle, organizations can improve sales performance, achieve larger deal sizes, increase win rates, and shorten sales cycles, ultimately driving growth and maximizing business impact.

UrbanSitter

Series C in 2017
UrbanSitter, Inc. is a childcare marketplace that connects parents with babysitters and nannies through shared connections. Founded in 2010 and based in San Francisco, the company operates in major cities including New York City, Chicago, Los Angeles, Seattle, Washington D.C., Boston, Denver, and San Diego. UrbanSitter offers an app and website that simplifies the process of finding, booking, and paying for trusted care across various needs, including child care, senior care, pet sitting, and household services. By leveraging a parent's personal network, UrbanSitter helps families find caregivers recommended by friends, co-workers, and local parents, ensuring a level of trust and reliability. The platform is particularly useful for last-minute childcare needs, boasting average response times of under three minutes. By addressing the challenges of securing reliable care, UrbanSitter provides families with essential support in their daily lives.

PerimeterX

Series B in 2017
PerimeterX, Inc. is a cybersecurity company that specializes in developing solutions to prevent automated attacks and malicious web behavior. Founded in 2014 and headquartered in San Mateo, California, with additional locations in London, Miami, and a subsidiary in Tel Aviv, the company offers a suite of products aimed at protecting web infrastructure. Its flagship solutions, known as PerimeterX Bot Defender, provide real-time defenses against various types of bot attacks, including those targeting websites, mobile applications, and APIs. By leveraging behavioral analytics and advanced threat detection techniques, PerimeterX helps organizations in sectors such as e-commerce, travel, and media safeguard their digital assets from account abuse, web scraping, and marketing fraud. The company's innovative approach has garnered recognition, including being listed among the top cybersecurity startups and promising artificial intelligence firms.

Unchained Labs

Series C in 2017
Unchained Labs is a life sciences tools company based in Pleasanton, California, specializing in solutions for biologics and gene therapy researchers. Established in 2014, it develops a range of products designed to enhance the efficiency and effectiveness of research in protein stability and formulation. Key offerings include the Optim platform, which allows researchers to measure multiple protein stability parameters simultaneously, and GRUNT, an automated system for biologic formulation preparation. In addition to these, the company provides various tools such as protein sizing systems, stability quantifiers, and automated buffer exchange systems. Unchained Labs serves biopharma and academic customers globally, distributing its products through partnerships in Europe, North and South America, Japan, and other Asian markets.

Vivace Therapeutics

Series B in 2017
Vivace Therapeutics, Inc. is a biotechnology company focused on the discovery and development of small molecule therapies aimed at treating cancer. Founded in 2014 and located in the San Francisco Bay Area, the company specializes in targeting the Hippo pathway, which plays a critical role in regulating tissue regeneration and organ size. Vivace Therapeutics employs an innovative approach by leveraging research from leading academic institutions to develop novel therapeutics that can be used independently or in combination with existing treatments. The company is committed to advancing promising drug candidates and therapeutic technologies to address the unmet needs of cancer patients, driven by a mission to improve patient outcomes and quality of life.

Glooko

Series C in 2017
Glooko is a company that develops a remote patient-monitoring platform specifically designed for individuals with diabetes. This platform integrates with various diabetes devices, fitness wearables, and activity trackers to capture and sync health data. It provides comprehensive reports and analytics aimed at promoting behavior change and improving health outcomes. By enhancing communication between patients and healthcare providers, Glooko facilitates better management of diabetes and supports remote monitoring efforts. The platform is accessible on both Android and iOS devices, allowing users to conveniently track their diabetes-related information on their smartphones.

Iterum Therapeutics

Series B in 2017
Iterum Therapeutics plc is a clinical-stage pharmaceutical company based in Dublin, Ireland, focused on developing innovative anti-infectives to address the pressing issue of multi-drug resistant pathogens. Founded in 2015, the company is advancing sulopenem, a novel penem anti-infective compound that is currently undergoing Phase III clinical trials. Sulopenem is designed for both oral and intravenous use and aims to treat various serious infections, including uncomplicated and complicated urinary tract infections as well as complicated intra-abdominal infections. The company’s mission is to significantly improve the lives of patients affected by serious and life-threatening diseases by providing effective solutions to antibiotic resistance.

Onkos Surgical

Series B in 2017
Onkos Surgical Inc. is a privately-held company based in Parsippany, New Jersey, focused on providing advanced technologies and solutions for surgical oncologists. Founded in 2014, Onkos Surgical is dedicated to transforming the treatment of musculoskeletal cancers and complex orthopedic conditions. The company offers innovative products such as GenVie, a magnesium bone scaffolding technology, and the ELEOS Proximal Tibia, a 3D printed limb salvage replacement. By leveraging cutting-edge techniques in virtual surgical planning, 3D modeling and printing, and personalized surgical planning, Onkos Surgical aims to enhance patient outcomes and improve the overall experience for both patients and healthcare professionals.

Antiva Biosciences

Series C in 2017
Antiva Biosciences, Inc. is a biopharmaceutical company based in South San Francisco, California, focused on developing antiviral therapies for human papillomavirus (HPV) infections. Established in 2012, the company aims to prevent cancer by treating precancerous lesions associated with HPV. Antiva's innovative approach includes localized therapeutics and small molecule antivirals that target HPV and other viral infections. The company is currently conducting clinical trials for high-grade anal intraepithelial neoplasias and high-grade cervical intraepithelial neoplasias. Through its medicinal chemistry platform, Antiva strives to enhance health outcomes for patients affected by HPV-related diseases and other viral infections.

UNIFi Software

Series B in 2017
Unifi Software, Inc. develops a suite of self-service data integration tools designed for both business users and IT professionals. Its flagship products include the Unifi catalog, which utilizes AI technology for data crawling and asset collection, allowing users to identify and process critical data assets. This catalog supports user-friendly search, collaboration, and data governance for enhanced security. Additionally, the Unifi data platform facilitates data acquisition, discovery, enrichment, transformation, normalization, and formatting, while also handling unstructured data. IT professionals benefit from features that enable connection to data sources, user authorization, and resource management. The platform is accessible through the Microsoft Azure Marketplace and offers solutions for various applications, including audience analytics and cloud migration. Founded in 2013 and based in San Mateo, California, Unifi Software operates as a subsidiary of Boomi, Inc.

Apartment List

Series B in 2016
Apartment List, Inc., established in 2008 and headquartered in San Francisco, operates an online rental marketplace connecting renters and landlords across the United States. Its platform streamlines the housing search by offering personalized, curated listings based on users' preferences, ensuring a simple, enjoyable, and transparent process.

Leanplum

Series C in 2016
Leanplum Inc. is a mobile marketing platform that specializes in enhancing engagement for brands through a unified, multichannel approach. Founded in 2012 and headquartered in San Francisco, with additional offices in New York, London, Bulgaria, and Amsterdam, Leanplum enables businesses to optimize their mobile applications and marketing efforts. The platform offers a range of services including messaging, automation, app editing, personalization, A/B testing, and analytics, allowing product teams to conduct real-time optimization tests and analyze results effectively. Renowned global brands such as Tinder, Grab, Tesco, and Zynga utilize Leanplum to orchestrate integrated campaigns that foster customer loyalty and drive growth. By transforming data into actionable insights, Leanplum helps companies understand user needs, delivering relevant experiences that enhance brand engagement and establish long-term customer relationships.

Glooko

Series C in 2016
Glooko is a company that develops a remote patient-monitoring platform specifically designed for individuals with diabetes. This platform integrates with various diabetes devices, fitness wearables, and activity trackers to capture and sync health data. It provides comprehensive reports and analytics aimed at promoting behavior change and improving health outcomes. By enhancing communication between patients and healthcare providers, Glooko facilitates better management of diabetes and supports remote monitoring efforts. The platform is accessible on both Android and iOS devices, allowing users to conveniently track their diabetes-related information on their smartphones.

Chrono Therapeutics

Series B in 2016
Chrono Therapeutics Inc. is a pharmaceutical company based in Hayward, California, focused on revolutionizing drug delivery and addiction management. Founded in 2003, the company specializes in the development of SmartStop, a digital nicotine replacement therapy that employs a wearable device to deliver programmable, transdermal drug therapy. This innovative system is designed to tailor the timing and dosage of nicotine while providing real-time behavioral support to help users manage addiction and smoking cessation effectively. Chrono Therapeutics aims to address the challenges associated with smoking addiction through its advanced technology, which seeks to achieve optimal clinical outcomes and improve the overall quality of life for users. The company's leadership team brings extensive experience in product development, research and development, and navigating regulatory pathways, positioning Chrono Therapeutics as a key player in the smoking cessation market.

Sample6

Series C in 2016
Sample6 is a biotechnology company that specializes in the development of a synthetic-biology based diagnostic system for bacteria. Its innovative technology enables enrichment-free detection of harmful bacteria, identifying levels as low as 1 CFU/ml within just four hours. The proprietary Bioillumination Platform, created by a team of researchers including Professor Tim Lu from MIT, allows for the engineering of bioparticles that target specific unwanted bacteria, illuminating them for detection. This system is coupled with sensitive sensor technology that provides rapid on-site results without the need for a laboratory. Sample6 aims to enhance public health and safety by enabling quick and efficient detection of harmful bacteria across various industries, including food production, retail, and healthcare, addressing environments where humans and bacteria interact.

Rocketrip

Series B in 2016
Rocketrip, Inc. is a travel management platform founded in 2013 and based in New York, New York. The company focuses on enabling employees to make cost-effective travel decisions while earning rewards for saving on expenses. Its platform provides real-time insights into reasonable travel spending, allowing users to compare costs and choose lower-priced options for flights, cars, and hotels without disrupting their online booking process. By establishing a custom-calibrated budget known as the Price to Beat, Rocketrip incentivizes employees to select economical travel arrangements, thereby promoting a culture of cost savings within organizations. The platform is utilized by several enterprise brands, demonstrating its effectiveness in the corporate travel sector. As of September 2020, Rocketrip operates as a subsidiary of Mondee Holdings Inc.
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