The Bill & Melinda Gates Foundation is an independent non-profit organization based in Seattle, Washington, established in 2000. It is dedicated to reducing global inequities by focusing on improving health, alleviating extreme poverty, and supporting educational initiatives. The foundation also engages in community giving within the Pacific Northwest, promoting strategies and programs that assist low-income families. With regional offices in Washington, D.C.; New Delhi, India; Beijing, China; and London, United Kingdom, the foundation is governed by its co-founders, Bill and Melinda Gates, along with trustee Warren Buffett. Its mission encompasses a wide range of global challenges, aiming to create lasting change through targeted grant-making and programmatic efforts.
Director, Global Health Discovery and Translational Sciences
Keith Klugman
Director
Trevor Mundel
President, Global Health
Rob Nabors
Director, North America
Lynda Stuart
Deputy Director
Mark Suzman
President, Global Policy and Advocacy
Chris Wilson
Director
Past deals in Healthcare
Likarda
Grant in 2025
Likarda is a biotechnology company focused on developing innovative cell therapies and delivery technologies. Utilizing its patented Core-Shell Spherification® platform, Likarda specializes in cell encapsulation within biocompatible hydrogels, such as Hyaluronic Acid and PEG, which allows for customized delivery solutions tailored to the unique specifications of various cell therapies. The company's approach enables the creation of microcapsules that can provide injectable treatments with enhanced localization and efficacy or offer immunoprotective barriers for long-term cell transplants. Likarda is actively working on therapies for diabetes and osteoarthritis, including the delivery of islet-like cells for diabetes treatment and the slow-release injection of encapsulated stem cells for alleviating joint pain and reversing osteoarthritis degradation. The company has achieved significant recognition, including being named one of the "50 Most Promising Start-Ups in the World." To date, Likarda has secured over $8 million in funding through private investments, grants, and contract services.
Vitrivax
Grant in 2024
VitriVax is a biotechnology startup based in Boulder, Colorado, focused on developing an innovative vaccine formulation platform. The company utilizes its proprietary atomic layering thermostable antigen and adjuvant (ALTA) technology to create vaccines that are more effective, affordable, and accessible worldwide. This technology addresses the challenges associated with vaccine stability and administration by enabling the development of thermostable, single-shot vaccines that can effectively incorporate both prime and booster doses. VitriVax's advancements in vaccine formulation aim to eliminate barriers to global vaccination, ultimately enhancing immune responses for a broad range of medical indications. The company has received significant funding, including over $5 million from various sources such as the National Institutes of Health, the National Science Foundation, and the Bill and Melinda Gates Foundation, to support its mission.
Freya Biosciences
Series A in 2024
Freya Biosciences is a clinical-stage company focused on women's health, with operations in Copenhagen and Boston. It specializes in developing microbial immunotherapies aimed at addressing significant unmet medical needs across various conditions. The company utilizes a proprietary platform to engineer and manufacture live microbes, ensuring their safety and efficacy for human use. Through this innovative approach, Freya Biosciences seeks to create new treatment options for a range of diseases, striving to make a meaningful impact in the healthcare sector.
La Ruche Health
Grant in 2024
La Ruche Health provides an innovative platform that connects patients with virtual and at-home healthcare services. Utilizing health AI technology, it offers advice and facilitates the booking of medical services and lab tests through user-friendly applications on iOS, Android, and WhatsApp. The company has recognized WhatsApp as a key distribution channel, being the first to integrate generative AI into this platform to enhance conversational experiences, particularly for low-literacy communities. Additionally, La Ruche Health develops a medical record management system that enables healthcare teams to efficiently manage and exchange medical data through both web and mobile applications. This comprehensive platform allows for virtual and physical consultations, as well as access to a wellness marketplace designed to make modern health services more affordable and accessible to various communities.
CanSino Biologics
Grant in 2024
CanSino Biologics focuses on the R&D, manufacturing, and commercialization of vaccine products for human use. These vaccine products include pneumococcal polysaccharide and conjugate vaccines, and a DTcP-based combo, and other items. It is also dedicated to the development of new vaccine-like recombinant adenovirus vector-based tuberculosis vaccines and a recombinant protein-based pneumococcal vaccine.
Immorna
Grant in 2024
Immorna is a biotechnology company focused on developing RNA-based therapeutics and vaccines. The company employs various RNA platforms, including conventional, self-replicating, and circular RNA, to create innovative treatments. Immorna has established a comprehensive central management console for RNA synthesis, purification, and analytical testing, which facilitates both clinical and commercial development. Additionally, the company has developed advanced screening tools and a range of RNA delivery vehicles, such as polymers and lipid nanoparticles, incorporating proprietary ionizable cationic lipids. This robust infrastructure positions Immorna to contribute significantly to the field of RNA therapeutics.
Noze
Venture Round in 2024
Noze is a leader in digital odor perception technology, creating advanced solutions that replicate the human sense of smell. Their sophisticated digital nose utilizes a specialized sensor, developed with NASA technology, to detect and identify odors in various real-world environments. This technology collects and analyzes data through an AI engine, allowing healthcare providers to assess air quality, monitor chemical footprints, and potentially diagnose diseases based on breath-based odor biomarkers. By enabling real-time disease detection and routine health screenings with a single exhale, Noze aims to enhance human health and well-being while improving patient outcomes.
Nanite
Grant in 2024
Nanite is a biotechnology company focused on non-viral gene delivery through the development of programmable polymer nanoparticles. Utilizing an artificial intelligence-driven platform, Nanite combines advanced high-throughput experimental and computational methods to create tailored delivery vehicles. These vehicles are designed to effectively transport a wide range of genetic materials with specific targeting capabilities, facilitating research in functional chemistry and enhancing the design of therapeutically relevant gene delivery systems.
Owlstone Medical
Grant in 2024
Owlstone Medical Ltd is a diagnostics company based in Cambridge, United Kingdom, specializing in non-invasive breath-based diagnostic tools aimed at the early detection of diseases, including cancer and respiratory conditions. The company develops a range of innovative products, including its Breath Biopsy platform, which utilizes advanced technology to identify volatile organic compounds in breath samples. Its offerings include FAIMS technology for medical applications, Lonestar for disease biomarker detection, and ReCIVA breath samplers for in vitro analysis. Owlstone Medical's technology has significant applications in various medical fields, such as lung cancer, bowel cancer, and gastrointestinal disorders. The company is also exploring the development of a portable hand-held device that promises high sensitivity and selectivity for chemical detection, with potential applications across multiple markets, including military and industrial sectors. Owlstone Medical aims to become a leader in non-invasive diagnostics, with ongoing collaborations and trials, including contracts with the UK National Health Service for lung cancer screening initiatives.
Owlstone Medical
Venture Round in 2024
Owlstone Medical Ltd is a diagnostics company based in Cambridge, United Kingdom, specializing in non-invasive breath-based diagnostic tools aimed at the early detection of diseases, including cancer and respiratory conditions. The company develops a range of innovative products, including its Breath Biopsy platform, which utilizes advanced technology to identify volatile organic compounds in breath samples. Its offerings include FAIMS technology for medical applications, Lonestar for disease biomarker detection, and ReCIVA breath samplers for in vitro analysis. Owlstone Medical's technology has significant applications in various medical fields, such as lung cancer, bowel cancer, and gastrointestinal disorders. The company is also exploring the development of a portable hand-held device that promises high sensitivity and selectivity for chemical detection, with potential applications across multiple markets, including military and industrial sectors. Owlstone Medical aims to become a leader in non-invasive diagnostics, with ongoing collaborations and trials, including contracts with the UK National Health Service for lung cancer screening initiatives.
Corner Therapeutics
Grant in 2024
Corner Therapeutics is a biotechnology research company focused on immunotherapy. It specializes in developing technologies that stimulate exceptional memory T cells to achieve lifelong immunity. The company utilizes a versatile dendritic cell hyperactivation platform that induces strong T-cell responses, aiming to provide robust and durable immunity against a wide range of cancers and infectious diseases. By enhancing T-cell activation, Corner Therapeutics seeks to enable healthcare providers to promote lasting immunity and optimize immune regulation.
Ginkgo Bioworks
Grant in 2024
Ginkgo Bioworks is a biotechnology company based in Boston, Massachusetts, founded in 2008. It specializes in biological engineering, designing and developing custom microbes and organisms for various applications. The company discovers and licenses molecules used in flavors, sweeteners, cosmetic ingredients, crop treatments, and pharmaceuticals. Additionally, it offers probiotic bacteria aimed at protecting against infections and creates libraries of molecules for natural product discovery. Ginkgo Bioworks operates primarily in the markets of cultured ingredients, carbon mitigation, probiotics, and biosecurity. The biosecurity segment, which generates the majority of the company's revenue, provides data analytics and related services to organizations across diverse sectors, including food, agriculture, pharmaceuticals, and specialty chemicals.
Noze
Grant in 2024
Noze is a leader in digital odor perception technology, creating advanced solutions that replicate the human sense of smell. Their sophisticated digital nose utilizes a specialized sensor, developed with NASA technology, to detect and identify odors in various real-world environments. This technology collects and analyzes data through an AI engine, allowing healthcare providers to assess air quality, monitor chemical footprints, and potentially diagnose diseases based on breath-based odor biomarkers. By enabling real-time disease detection and routine health screenings with a single exhale, Noze aims to enhance human health and well-being while improving patient outcomes.
Evotec
Grant in 2023
Evotec is a drug discovery partnership firm that collaborates with pharmaceutical and biotechnology companies, academic institutions, and nonprofit organizations to advance innovative therapeutic solutions. The company specializes in a range of therapeutic areas, including central nervous system disorders, diabetes, inflammation, oncology, infectious diseases, and women's health. Approximately 80% of its revenue comes from shared research and development services, which involve fee-for-service work and integrated drug discovery collaborations utilizing proprietary assets. The remaining 20% of sales derive from its Just-Evotec Biologics segment, which provides contract development and manufacturing organization services for biologics. Evotec's approach emphasizes collaboration with various stakeholders, including patient advocacy groups and venture capitalists, to enhance drug discovery and development processes.
Brightseed
Grant in 2023
Brightseed, Inc. is a biotechnology company based in San Francisco, California, that specializes in the discovery of bioactive compounds in plants to enhance human health. Utilizing its advanced Forager platform, which employs artificial intelligence and machine learning algorithms, Brightseed accelerates the identification and validation of clinically beneficial molecules. This innovative approach enables the company to uncover connections between natural compounds and health outcomes, revealing the potential of bioactives that have previously remained uncharted. By integrating these discoveries back into the food supply chain, Brightseed collaborates with various companies across the consumer health continuum to develop science-backed health solutions aimed at managing chronic diseases and improving overall quality of life. Founded in 2017, Brightseed is committed to exploring the untapped resources of the plant kingdom to address pressing health challenges.
Ginkgo Bioworks
Grant in 2023
Ginkgo Bioworks is a biotechnology company based in Boston, Massachusetts, founded in 2008. It specializes in biological engineering, designing and developing custom microbes and organisms for various applications. The company discovers and licenses molecules used in flavors, sweeteners, cosmetic ingredients, crop treatments, and pharmaceuticals. Additionally, it offers probiotic bacteria aimed at protecting against infections and creates libraries of molecules for natural product discovery. Ginkgo Bioworks operates primarily in the markets of cultured ingredients, carbon mitigation, probiotics, and biosecurity. The biosecurity segment, which generates the majority of the company's revenue, provides data analytics and related services to organizations across diverse sectors, including food, agriculture, pharmaceuticals, and specialty chemicals.
Vitrivax
Grant in 2023
VitriVax is a biotechnology startup based in Boulder, Colorado, focused on developing an innovative vaccine formulation platform. The company utilizes its proprietary atomic layering thermostable antigen and adjuvant (ALTA) technology to create vaccines that are more effective, affordable, and accessible worldwide. This technology addresses the challenges associated with vaccine stability and administration by enabling the development of thermostable, single-shot vaccines that can effectively incorporate both prime and booster doses. VitriVax's advancements in vaccine formulation aim to eliminate barriers to global vaccination, ultimately enhancing immune responses for a broad range of medical indications. The company has received significant funding, including over $5 million from various sources such as the National Institutes of Health, the National Science Foundation, and the Bill and Melinda Gates Foundation, to support its mission.
Philips
Grant in 2023
Philips is a global technology company that specializes in healthcare, consumer lifestyle, and lighting products, solutions, and services. The company provides a wide range of offerings, including healthcare solutions, professional lighting products, oral healthcare items, and innovative display technologies. For consumers, Philips offers electronic products in categories such as sound and vision, personal care, mother and child care, housewares, and lighting. The company's commitment to improving health and well-being is evident in its focus on meaningful innovation and its efforts to address healthcare inequalities through initiatives like the Philips Foundation, which aims to enhance access to quality healthcare for disadvantaged communities.
BiomEdit
Grant in 2023
BiomEdit is an innovation company focused on developing novel probiotics and microbiome-derived bioactives to enhance animal health. The company aims to tackle significant challenges in animal agriculture and food security by harnessing the potential of the microbiome. Utilizing a unique platform that incorporates high-throughput sequencing and data analytics, BiomEdit rapidly discovers and screens new probiotic species and bioactive molecules. These innovations can be engineered for improved thermostability, increased production of beneficial metabolites, and expression of immune-modulating proteins. By creating next-generation products that promote animal health without relying on antibiotics, BiomEdit addresses critical needs in livestock production and disease management.
Axmed
Grant in 2023
Axmed is a business focuses on LMICs and strengthens the purchasing power of these markets to ensure the supply of cost-effective, high-quality medicines. We partner exclusively with authorized, high-quality pharmaceutical companies and certified caregivers to accelerate access to medicines.
GE HealthCare Technologies
Grant in 2023
GE Healthcare is a multinational healthcare company based in Chicago, Illinois, that specializes in manufacturing a diverse range of medical equipment and technologies. Founded in 1892, the company offers products and services including medical imaging, information technologies, medical diagnostics, and patient monitoring systems. GE Healthcare also supports drug discovery and biopharmaceutical manufacturing through intelligent devices and data analytics. The company aims to enhance patient care and outcomes by providing innovative healthcare solutions utilized in hospitals, clinics, research institutions, and pharmaceutical companies globally. By focusing on precision health and digitizing healthcare, GE Healthcare seeks to improve productivity and health outcomes for patients and healthcare providers alike. Additionally, the company pursues an aggressive acquisition strategy to strengthen its presence in emerging markets and expand its life sciences portfolio.
American University of Beirut
Grant in 2023
The American University of Beirut (AUB), established in 1866 and formerly known as Syrian Protestant College, is a prominent educational institution located in Beirut, Lebanon. Adhering to the American liberal arts model, AUB emphasizes a teaching-centered approach to research and education. It offers over 120 academic programs across six faculties: Agricultural and Food Sciences, Arts and Sciences, Engineering and Architecture, Health Sciences, Medicine, and Business Management. The university serves approximately 8,000 students, supported by around 800 instructional faculty, with a balanced gender ratio of 50 percent male and 50 percent female. AUB fosters an environment that encourages freedom of thought and expression, aiming to cultivate graduates equipped with critical thinking skills, personal integrity, and civic responsibility. The institution is accredited by the Commission on Higher Education of the Middle States Association of Colleges and Schools in the United States, having received its initial accreditation in 2004. Instruction is primarily conducted in English, except for specific language courses.
EHA Clinics
Grant in 2023
EHA Clinics is dedicated to providing accessible, effective, and affordable healthcare services. The organization offers a comprehensive healthcare network that includes routine medical care, laboratory services, pharmacy, optometry, dental care, urgent care, and specialist consultations. EHA Clinics ensures that members have round-the-clock access to healthcare through various channels, including physical locations, telehealth virtual visits, and home care services. By leveraging technology and a skilled team, EHA Clinics aims to enhance the healthcare experience, improve patient outcomes, and offer competitive pricing for individual, family, and business members.
Aegis Life
Grant in 2023
Aegis Life is a biotechnology company focused on advancing nucleic acid delivery technology, specifically through its proprietary platform known as fusogenix PLV. This technology, developed over two decades, is designed to facilitate the rapid development and commercialization of vaccines and therapeutics aimed at preventing and treating infectious diseases. Aegis Life's innovative approach supports the pharmaceutical industry in accelerating the discovery, clinical development, and manufacturing processes for vaccines and treatments, particularly in response to emerging health threats such as COVID-19.
Hyperfine
Grant in 2023
Hyperfine is a medical device company that developed Swoop, the first FDA-cleared point-of-care MRI system designed to enhance patient access to diagnostic imaging. Swoop operates at a lower magnetic field strength than traditional MRI machines, producing high-quality images quickly and efficiently. This portable system can be easily wheeled to a patient's bedside, plugged into a standard electrical outlet, and operated via an iPad, making it suitable for various clinical environments such as emergency departments and intensive care units. Hyperfine generates revenue through the sale of MRI devices and service sales, which include subscriptions for bundled devices, maintenance, and software. By providing rapid imaging capabilities at a fraction of the cost of conventional MRIs, Hyperfine aims to facilitate timely diagnoses and treatments for patients, regardless of their location or resources.
Medicines for All Institute
Grant in 2023
The Medicines for All Institute, operating under the auspices of the Virginia Commonwealth University School of Engineering.
Kallyope
Grant in 2023
Kallyope Inc. is a biotechnology company based in New York City that focuses on the gut-brain axis to develop innovative therapeutics and consumer products aimed at enhancing human health. Founded in 2014, Kallyope employs a multidisciplinary approach, integrating technologies such as sequencing, computational biology, neural imaging, and human genetics to deepen the understanding of gut-brain biology. This comprehensive understanding enables the company to create effective and well-tolerated oral medications targeting various health issues, including diabetes, obesity, gut disorders, inflammatory diseases, migraines, and allergies. With a team of experienced scientists and a strong foundation in drug discovery, Kallyope aims to address significant unmet medical needs through its research and development efforts.
Vir Biotechnology
Grant in 2023
Vir Biotechnology, Inc. is a clinical-stage immunology company based in San Francisco, California, that focuses on developing therapeutic products aimed at treating and preventing serious infectious diseases. The company is working on several key therapies, including VIR-2218 and VIR-3434 for hepatitis B, VIR-2482 for influenza A, VIR-1111 for human immunodeficiency virus, and VIR-2020 for tuberculosis. Vir Biotechnology employs advanced technologies and scientific expertise to manipulate immune responses and enhance pathogen-host interactions. The company has established collaborations and agreements with various organizations, including the Bill & Melinda Gates Foundation, National Institutes of Health, Brii Biosciences, Alnylam Pharmaceuticals, and others, to further its research and development efforts. Additionally, it has a manufacturing agreement with Samsung Biologics for producing antibodies related to COVID-19 treatments. Founded in 2016, Vir Biotechnology aims to leverage its innovative platforms to potentially eradicate diseases like hepatitis B, influenza A, HIV, and tuberculosis.
Audere
Grant in 2023
Audere is a digital health nonprofit developing software to improve global health in underserved communities.
Smart Immune
Grant in 2023
Smart Immune is a clinical-stage biotechnology company focused on developing innovative hematopoietic stem cell-based therapies aimed at improving the prognosis and quality of life for patients with serious diseases. The company's primary program utilizes T cell progenitors, known as ProTcells, which are designed to facilitate a rapid and safe immune recovery following transplantation. This therapy seeks to provide a polyclonal immune response, enhancing the body's ability to combat cancers and infections. Additionally, Smart Immune plans to complement its core offerings with advancements in targeted conditioning, gene therapy, and genome editing, thereby creating next-generation treatments for a range of inherited blood disorders and hematological malignancies.
Evotec
Grant in 2023
Evotec is a drug discovery partnership firm that collaborates with pharmaceutical and biotechnology companies, academic institutions, and nonprofit organizations to advance innovative therapeutic solutions. The company specializes in a range of therapeutic areas, including central nervous system disorders, diabetes, inflammation, oncology, infectious diseases, and women's health. Approximately 80% of its revenue comes from shared research and development services, which involve fee-for-service work and integrated drug discovery collaborations utilizing proprietary assets. The remaining 20% of sales derive from its Just-Evotec Biologics segment, which provides contract development and manufacturing organization services for biologics. Evotec's approach emphasizes collaboration with various stakeholders, including patient advocacy groups and venture capitalists, to enhance drug discovery and development processes.
Noze
Grant in 2023
Noze is a leader in digital odor perception technology, creating advanced solutions that replicate the human sense of smell. Their sophisticated digital nose utilizes a specialized sensor, developed with NASA technology, to detect and identify odors in various real-world environments. This technology collects and analyzes data through an AI engine, allowing healthcare providers to assess air quality, monitor chemical footprints, and potentially diagnose diseases based on breath-based odor biomarkers. By enabling real-time disease detection and routine health screenings with a single exhale, Noze aims to enhance human health and well-being while improving patient outcomes.
VisualDx
Grant in 2023
VisualDx is a clinical decision support system that aims to improve diagnostic accuracy and patient safety in healthcare settings. By integrating a curated medical image library with a robust search engine, it provides clinicians with patient-specific answers swiftly, facilitating informed therapeutic decisions. The platform encompasses high-quality images covering a range of both pediatric and adult medical conditions. Used by over 2,300 hospitals, clinics, and medical schools globally, VisualDx enhances point-of-care decisions and fosters better patient engagement, enabling healthcare providers to deliver timely and effective care.
LumiraDx
Grant in 2022
LumiraDx Ltd, incorporated in 2016 and based in London, is a next-generation healthcare company specializing in point-of-care diagnostics. The company manufactures a diagnostic platform designed to provide lab-comparable performance across a wide range of tests, enhancing patient-centered care. LumiraDx aims to simplify and improve diagnostic-led care by offering a compact, portable instrument paired with advanced, low-cost test strips and seamless digital connectivity. Its solutions are focused on achieving healthcare transformation goals by delivering integrated and informed care, resulting in safer, more efficient practices with better patient outcomes. The company operates in multiple countries, including the United States, Italy, Germany, and Sweden, with a significant portion of its revenue generated in the U.S.
Aspen Pharmacare
Grant in 2022
Aspen Pharmacare Holdings Limited is a global pharmaceutical company headquartered in Durban, South Africa, specializing in the manufacture and supply of both branded and generic pharmaceutical products. It operates primarily through two segments: Commercial Pharmaceuticals and Manufacturing. Aspen offers a diverse range of products, including general anaesthetics, muscle relaxants, cytotoxic medications, and injectable anticoagulants, particularly focusing on low molecular weight heparins and Xa inhibitors. The company also engages in the contract production and supply of active pharmaceutical ingredients (APIs) and finished pharmaceuticals for third parties. With a presence in over 150 countries, Aspen serves various markets, including South Africa, Australia, and several nations across Europe and Asia. Its extensive capabilities in manufacturing encompass both API and finished dosage forms, addressing a wide array of therapeutic needs. Founded in 1850, Aspen has expanded its reach significantly through strategic acquisitions, enhancing its footprint in emerging markets and contributing to a diverse portfolio of healthcare solutions.
Dare Bioscience
Grant in 2022
Daré Bioscience is a healthcare company committed to the development and commercialization of innovative products in women’s reproductive health.
Contro
Grant in 2022
Contro is an online prescription and delivery service for sexual health and confidence products such as birth control and erectile dysfunction treatment. Contro, through its secure digital platform, allows individuals to take control of their personal wellness by offering a convenient, affordable and discreet subscription service. Offering a cancel anytime policy, Contro makes it easier than ever to obtain sexual health products in South Africa.
Bayer
Grant in 2022
Bayer is a global enterprise based in Germany, specializing in life sciences with a strong focus on health care and agriculture. The company develops and commercializes a wide range of products, including pharmaceuticals, consumer health items, and crop science solutions. Bayer's pharmaceutical division offers a variety of medications, while its consumer health segment includes vitamins and food supplements. In agriculture, Bayer provides seeds and crop protection products, including pesticides, herbicides, and fungicides, significantly expanded through the acquisition of Monsanto. Additionally, Bayer is a leader in animal health, contributing to the well-being of both human and animal populations. Overall, Bayer aims to create innovative solutions that address critical challenges in health and nutrition.
CQUIN Learning Network
Grant in 2022
CQUIN is made up of representatives from ministries of health, implementing partners, civil society, associations of people living with HIV, academic institutions, and donor agencies that work with CQUIN to scale up DSD according to each country’s unique needs. The company encourages experience sharing, peer-to-peer learning, and collaborative issue solving. It allows member countries to obtain technical support from Columbia University's ICAP.
CaliberMRI
Grant in 2022
CaliberMRI is a platform that includes brain, breast, prostate, and custom phantoms, and companion automated quality control software. They provide services that include quantitative MRI, qmri, phantoms, quantitative medicine, radiology, breast cancer, and calibration.
Sapient
Grant in 2022
Sapient enables the discovery of circulating small molecule biomarkers at unprecedented speed and scale. Leveraging next-generation mass spectrometry, biocomputational analysis, and large-scale human biology databases, its platform supports the rapid identification and validation of circulating biomarkers of health, disease, and drug response which are needed to align patients, disease biology, and specific therapies.
SwipeRx
Series B in 2022
SwipeRx is a digital platform designed to enhance the operations of pharmacies by connecting pharmaceutical manufacturers, pharmacies, and patients. It offers a range of services, including specialized healthcare logistics, negotiated pricing, and financing solutions, creating a robust network for pharmacy purchasing. The platform generates insights that facilitate collaboration with pharmacies, improve pharmacist education, and strengthen market access. Additionally, it optimizes commercial strategies and enhances daily operational efficiencies. By providing real-time access to patient and sell-out data, SwipeRx enables its clients to improve patient affordability, access, and adherence to medications.
Cardea Bio
Grant in 2022
Cardea Bio, Inc. is a biotechnology company based in San Diego, California, focused on developing and commercializing bioelectronics for research and diagnostics. Established in 2013, Cardea utilizes proprietary graphene-based digital biosensors to create advanced biosensor hardware, software, and molecular infrastructure, enabling precision healthcare through improved diagnostic capabilities. The company's product offerings include the AGILE R100, an innovative assay for drug discovery, and the AGILE R200, an automated high-throughput screening solution. Cardea's biosensors convert biomolecular interactions into digital data, allowing for real-time biological signal analysis and access to streaming multi-omics data. Their solutions cater to various applications in life sciences and healthcare, such as small molecule validation, antibody characterization, and biomolecular analysis.
Yemaachi Biotechnology
Grant in 2022
Yemaachi Biotechnology is focused on advancing the diagnosis and treatment of cancer through innovative therapeutic technologies. The company employs immunogenomics, bioinformatics, and artificial intelligence to enhance the development of effective cancer detection and treatment strategies. By leveraging these advanced methodologies, Yemaachi aims to lower the economic burden of cancer and improve patient outcomes through more accurate and efficient therapeutic solutions.
Butterfly Network
Grant in 2022
Butterfly Network develops innovative medical imaging devices designed to enhance point-of-care ultrasound programs in hospitals and healthcare organizations. Founded in 2011 and based in Guilford, Connecticut, the company has created the first handheld, single-probe whole-body ultrasound system, utilizing its patented Ultrasound-on-Chip technology. This compact device enables healthcare professionals to perform diagnostic imaging across various medical fields, including cardiology, urology, and obstetrics, all while integrating seamlessly into clinical workflows through mobile applications. Butterfly Network aims to democratize access to medical imaging, particularly for the 4.7 billion individuals globally who currently lack access to ultrasound, thereby promoting early detection and remote management of health conditions.
Evotec
Grant in 2021
Evotec is a drug discovery partnership firm that collaborates with pharmaceutical and biotechnology companies, academic institutions, and nonprofit organizations to advance innovative therapeutic solutions. The company specializes in a range of therapeutic areas, including central nervous system disorders, diabetes, inflammation, oncology, infectious diseases, and women's health. Approximately 80% of its revenue comes from shared research and development services, which involve fee-for-service work and integrated drug discovery collaborations utilizing proprietary assets. The remaining 20% of sales derive from its Just-Evotec Biologics segment, which provides contract development and manufacturing organization services for biologics. Evotec's approach emphasizes collaboration with various stakeholders, including patient advocacy groups and venture capitalists, to enhance drug discovery and development processes.
Elarex
Grant in 2021
Elarex is a Canadian healthcare technology company commercializing its proprietary PT120 formulation technology which has proven to stabilize biologicals (including live vaccines!) so that they are as effective when stored at 40C as if they had been stored at -80C.
Providence Therapeutics
Grant in 2021
Providence Therapeutics is a biotechnology company that develops a personalized mRNA cancer vaccine designed to treat advanced ovarian cancer. The company's vaccine identifies tumor mutations and elicits an immune response against the tumor cells, enabling users to treat themselves and live life to the fullest. It aims to provide safe and effective medicines for people suffering from diseases with unmet medical needs. Scott Leary, Eric Marcusson, and Bradley Sorenson established the company in Toronto, Ontario in 2015.
Inventprise
Grant in 2021
Inventprise is a biotechnology company based in Redmond, Washington, focused on developing vaccines to combat infectious diseases. Established in 2012, the company is known for its 25-valent pneumococcal conjugate vaccine (PCV), which is supported by significant funding from the Bill and Melinda Gates Foundation, exceeding $100 million. This vaccine is specifically designed for large-scale distribution in low- and middle-income countries. In addition to vaccine development, Inventprise offers comprehensive contract manufacturing and development services, including quality control assays, batch records, and training. The company also operates a fully equipped quality control laboratory that conducts testing for identity, potency, purity, and stability, thereby assisting clients in addressing health disparities and promoting public health.
Philips
Grant in 2021
Philips is a global technology company that specializes in healthcare, consumer lifestyle, and lighting products, solutions, and services. The company provides a wide range of offerings, including healthcare solutions, professional lighting products, oral healthcare items, and innovative display technologies. For consumers, Philips offers electronic products in categories such as sound and vision, personal care, mother and child care, housewares, and lighting. The company's commitment to improving health and well-being is evident in its focus on meaningful innovation and its efforts to address healthcare inequalities through initiatives like the Philips Foundation, which aims to enhance access to quality healthcare for disadvantaged communities.
Brightseed
Grant in 2021
Brightseed, Inc. is a biotechnology company based in San Francisco, California, that specializes in the discovery of bioactive compounds in plants to enhance human health. Utilizing its advanced Forager platform, which employs artificial intelligence and machine learning algorithms, Brightseed accelerates the identification and validation of clinically beneficial molecules. This innovative approach enables the company to uncover connections between natural compounds and health outcomes, revealing the potential of bioactives that have previously remained uncharted. By integrating these discoveries back into the food supply chain, Brightseed collaborates with various companies across the consumer health continuum to develop science-backed health solutions aimed at managing chronic diseases and improving overall quality of life. Founded in 2017, Brightseed is committed to exploring the untapped resources of the plant kingdom to address pressing health challenges.
Titan Pharmaceuticals
Post in 2021
Titan Pharmaceuticals, Inc. is a biopharmaceutical Company developing proprietary therapeutics primarily for the treatment of serious medical disorders. Titan’s principal asset is Probuphine®, the first slow-release implant formulation of buprenorphine hydrochloride (“buprenorphine”), designed to maintain a stable, round-the-clock blood level of the medicine in patients for up to six months following a single treatment. The outpatient treatment of opioid dependence with daily dosed sublingual buprenorphine formulations represents a $1.3 billion market in the U.S., and a seven day transdermal patch formulation of buprenorphine for the treatment of chronic pain was launched in the U.S. in 2011. This novel implant formulation is inserted subdermally in a patient’s upper arm providing continuous medication, and has the potential to enhance patient compliance to treatment, and limit diversion for illicit use and accidental exposure to the sublingual formulations. The New Drug Application (NDA) was submitted to the FDA in October, 2012 seeking approval for treatment of opioid dependence. In December 2012, Titan entered into a license agreement with Braeburn Pharmaceuticals Sprl (“Braeburn”) that grants Braeburn exclusive commercialization rights to Probuphine® in the United States and Canada. Titan received a non-refundable up-front license fee of $15.75 million and will receive a $50 million milestone payment upon the approval of the NDA by the FDA. Additionally, Titan will be eligible to receive up to $130 million upon achievement of specified sales milestones and up to $35 million in regulatory milestones in the event of future NDA submissions and approvals for additional indications, including chronic pain. Titan will receive tiered royalties on net sales of Probuphine ranging from the mid-teens to the low twenties. Probuphine is the first product to utilize ProNeura™, a novel, proprietary, long-term drug delivery technology. The ProNeura technology has the potential to be used in developing products for the treatment of other chronic conditions, such as Parkinson’s disease, where maintaining stable, round-the-clock blood levels of a drug can benefit the patient and improve medical outcomes. Finally, Titan is also entitled to royalty revenue of 8-10% of net sales of Fanapt® (iloperidone), an atypical antipsychotic compound being marketed in the U.S. for the treatment of schizophrenia by Novartis Pharma AG (“Novartis”) under a sub-license agreement based on a licensed U.S. patent that expires in October 2016 (does not include a possible six month pediatric extension). Substantially all of this future royalty revenue has been sold to Deerfield Management (“Deerfield”), a healthcare investment fund, in exchange for cash and debt considerations which have been used to advance the development of Probuphine and for general corporate purposes.
Icosavax
Grant in 2020
Icosavax, Inc. is a biotechnology company based in Seattle, Washington, founded in 2017. The company specializes in developing vaccines using its innovative virus-like particle (VLP) technology platform, which allows for the multivalent display of complex viral antigens. This technology aims to provide broad and durable protection against various infectious diseases, with an initial focus on life-threatening respiratory illnesses. Icosavax's pipeline includes vaccine candidates targeting respiratory syncytial virus (RSV), human metapneumovirus (hMPV), and SARS-CoV-2. The company is dedicated to advancing its VLP technology to discover, develop, and ultimately commercialize effective vaccines against these infectious diseases.
Ilara Health
Grant in 2020
Ilara Health, founded in 2018 and headquartered in Nairobi, Kenya, focuses on enhancing healthcare access in rural Africa by developing and distributing AI-powered diagnostic devices. These compact devices are designed for primary care doctors in peri-urban and rural clinics, providing accurate and affordable diagnostic services. Ilara Health integrates its technology within a proprietary platform that connects to an electronic medical record system, allowing healthcare providers to efficiently record and manage patient data. By leveraging existing healthcare infrastructure, Ilara Health aims to improve the accessibility and affordability of diagnostic services in underserved regions.
Evotec
Grant in 2020
Evotec is a drug discovery partnership firm that collaborates with pharmaceutical and biotechnology companies, academic institutions, and nonprofit organizations to advance innovative therapeutic solutions. The company specializes in a range of therapeutic areas, including central nervous system disorders, diabetes, inflammation, oncology, infectious diseases, and women's health. Approximately 80% of its revenue comes from shared research and development services, which involve fee-for-service work and integrated drug discovery collaborations utilizing proprietary assets. The remaining 20% of sales derive from its Just-Evotec Biologics segment, which provides contract development and manufacturing organization services for biologics. Evotec's approach emphasizes collaboration with various stakeholders, including patient advocacy groups and venture capitalists, to enhance drug discovery and development processes.
Dare Bioscience
Grant in 2020
Daré Bioscience is a healthcare company committed to the development and commercialization of innovative products in women’s reproductive health.
Sapient
Grant in 2020
Sapient enables the discovery of circulating small molecule biomarkers at unprecedented speed and scale. Leveraging next-generation mass spectrometry, biocomputational analysis, and large-scale human biology databases, its platform supports the rapid identification and validation of circulating biomarkers of health, disease, and drug response which are needed to align patients, disease biology, and specific therapies.
Dynavax Technologies
Grant in 2020
Dynavax Technologies Corporation is a biopharmaceutical company based in Emeryville, California, focused on developing and commercializing innovative vaccines. The company's primary product, HEPLISAV-B, is an approved hepatitis B vaccine designed to prevent infection from all known subtypes of the virus in adults aged 18 and older. Dynavax is also advancing its proprietary CpG 1018 adjuvant to enhance vaccine efficacy and is engaged in various collaborations aimed at developing adjuvanted vaccines for COVID-19, pertussis, and universal influenza. In addition to its commercial efforts, Dynavax is involved in research partnerships with organizations such as Clover Biopharmaceuticals, the University of Queensland, and the Coalition for Epidemic Preparedness Innovations to create new vaccine candidates. The company was originally founded in 1996 as Double Helix Corporation and rebranded to its current name in September 1996.
HJF Medical Research International
Grant in 2020
HJF Medical Research International is an NGO that supports international programs advancing medical research and HIV prevention.
Dare Bioscience
Grant in 2020
Daré Bioscience is a healthcare company committed to the development and commercialization of innovative products in women’s reproductive health.
Montreal Heart Institute
Grant in 2020
Montreal Heart Institute is a specialty hospital dedicated to the development of cardiology.
Vaxxas
Grant in 2020
Vaxxas is a biotechnology company based in Brisbane, Australia, that specializes in developing a needle-free vaccination technology aimed at transforming vaccine delivery. The company's innovative system employs an array of vaccine-coated micro projections that penetrate the outer layers of the skin when applied with a specialized applicator device. This approach allows for direct deposition of vaccines among a dense concentration of immune cells in the skin. Additionally, Vaxxas utilizes proprietary dry-coating technology to minimize or eliminate the need for refrigeration during the storage and transport of vaccines, thereby alleviating the logistical challenges associated with maintaining the cold chain. Founded in 2011, Vaxxas aims to enhance global vaccination efforts through its novel delivery system.
Centre for Innovation in Regulatory Science
Grant in 2020
Centre for Innovation in Regulatory Science is a neutral, independently managed UK-based subsidiary company, forming part of the Clarivate Analytics group. CIRS provides an international forum for industry, regulators, HTA and other healthcare stakeholders to meet, debate and develop regulatory and reimbursement policy through the innovative application of regulatory science and to facilitate access to medical products. This is CIRS’ purpose. CIRS is operated solely for promotion of its purpose. The organisation has its own dedicated management and advisory boards, and its funding is derived from membership dues, related activities, special projects and grants.
Biological Dynamics
Grant in 2020
Biological Dynamics Inc. is a healthcare company based in San Diego, California, focused on enhancing global health outcomes through early disease detection. The company has developed a proprietary technology platform that enables the direct and selective capture of large necrotic particles from physiological solutions, including whole blood, serum, and plasma. This platform facilitates the analysis of native-state biomarkers and nanoparticles, supporting multiomics applications. Biological Dynamics specializes in cancer detection and offers a range of services, including the TR(ACE) Assay for monitoring treatment responses and tumor burdens, as well as liquid biopsy testing for personalized medicine. Additionally, the company provides clinical laboratory services, including molecular and next-generation sequencing, and has programs aimed at drug development in areas such as Alzheimer's disease. Founded in 2008, Biological Dynamics is committed to utilizing machine learning and its advanced technology to address various health challenges, including autoimmune diseases, transplant rejection, and traumatic brain injury.
VisualDx
Grant in 2020
VisualDx is a clinical decision support system that aims to improve diagnostic accuracy and patient safety in healthcare settings. By integrating a curated medical image library with a robust search engine, it provides clinicians with patient-specific answers swiftly, facilitating informed therapeutic decisions. The platform encompasses high-quality images covering a range of both pediatric and adult medical conditions. Used by over 2,300 hospitals, clinics, and medical schools globally, VisualDx enhances point-of-care decisions and fosters better patient engagement, enabling healthcare providers to deliver timely and effective care.
1mg
Venture Round in 2020
1mg is a digital consumer healthcare platform based in Gurgaon, Haryana, India, that aims to make healthcare more accessible, understandable, and affordable. Launched in 2015, it allows users to find detailed information about medicines prescribed by doctors and purchase them directly. The platform enables users to search for drugs based on ailments, classes, companies, and brands. Additionally, 1mg offers a service that helps consumers find the right healthcare professionals tailored to their needs. Its diagnostics service enhances transparency and cost-effectiveness in lab tests, empowering Indian consumers and caregivers to choose appropriate healthcare services at competitive prices.
Credence MedSystems
Grant in 2019
Credence MedSystems is a drug delivery and specialty pharmaceutical company focused on delivering medications safely for the benefit of our patients, caregivers and partners. Credence MedSystems has changed the paradigm for drug manufacturers commercializing an injectable drug in a differentiated delivery system. The award-winning Companion Safety Syringe System combines a fully compliant, best-in-class injectable drug delivery system with a vastly simplified path to market for our pharma/biotech partners. This is called Innovation Without Change because we offer the innovation of the final device without the change that customarily accompanies combination product development.
Lyndra Therapeutics
Grant in 2019
Lyndra Therapeutics, Inc. is a biotechnology company that specializes in the development of ultra-long-acting oral medicines. Founded in 2015 and headquartered in Watertown, Massachusetts, the company focuses on creating orally administered dosage forms that can deliver a sustained release of medications for periods ranging from a week to a month while remaining in the stomach. Lyndra's therapeutic initiatives target a variety of conditions, including Alzheimer's disease, cardiovascular and metabolic disorders, psychiatric issues, opioid use disorders, immunology, HIV, malaria vector control, and oral contraceptives. By enhancing medication adherence and improving health outcomes, Lyndra Therapeutics aims to contribute to lower healthcare costs and better patient care.
Halodoc
Series B in 2019
PT HaloDoc is a digital healthcare platform based in Jakarta, Indonesia, founded in 2016. It connects patients with a network of 19,000 licensed doctors and 1,000 certified partner pharmacies through its services. Users can engage with medical professionals via video calls, voice calls, and chat, making healthcare more accessible. The platform also allows patients to order laboratory tests that can be conducted at home. Additionally, HaloDoc helps users locate the nearest hospitals and clinics, streamlining the process of obtaining medical advice and services in real-time.
Biological Dynamics
Grant in 2019
Biological Dynamics Inc. is a healthcare company based in San Diego, California, focused on enhancing global health outcomes through early disease detection. The company has developed a proprietary technology platform that enables the direct and selective capture of large necrotic particles from physiological solutions, including whole blood, serum, and plasma. This platform facilitates the analysis of native-state biomarkers and nanoparticles, supporting multiomics applications. Biological Dynamics specializes in cancer detection and offers a range of services, including the TR(ACE) Assay for monitoring treatment responses and tumor burdens, as well as liquid biopsy testing for personalized medicine. Additionally, the company provides clinical laboratory services, including molecular and next-generation sequencing, and has programs aimed at drug development in areas such as Alzheimer's disease. Founded in 2008, Biological Dynamics is committed to utilizing machine learning and its advanced technology to address various health challenges, including autoimmune diseases, transplant rejection, and traumatic brain injury.
Univercells
Grant in 2019
Univercells is a provider of biomanufacturing solutions focused on making biologics, including vaccines and therapeutics, more accessible and affordable. The company offers innovative technologies designed to reduce manufacturing costs significantly, achieving up to 90% savings on the cost of goods and over 75% in capital investment. Their approach utilizes single-use technologies and integrates three manufacturing steps—cell culture under perfusion, clarification, and capture—into a simulated continuous mode. Univercells also provides a range of biomanufacturing services, including scale-X hydro, scale-X carbo, and NevoLine, along with integrated support such as equipment confirmation, facility design, and bioprocess excellence. This comprehensive offering aids cell and gene therapy manufacturers in scaling their operations from research and development to commercial production, ultimately addressing global health challenges.
Medsaf
Seed Round in 2019
Medsaf is a pharmaceutical platform based in Lagos, Nigeria, that facilitates the delivery of medications to hospitals, pharmacies, and clinics. Founded in 2014, the company offers a wide range of products, including antacids, antiviral drugs, anaemia treatments, antiseptics, and vitamins. Medsaf aims to enhance the accessibility of affordable, quality medications through an integrated suite of technologies designed to improve efficiency and transparency in the supply chain. Its services include online product distribution, quality control as a service, and a marketplace that connects healthcare providers with vetted suppliers and logistics partners. Additionally, Medsaf features an embedded finance platform that provides buy-now-pay-later solutions for medication procurement, streamlining the financial aspects of the pharmaceutical supply process.
Iyeza Health
Seed Round in 2019
Iyeza Health specializes in the supply chain and distribution of health products, focusing primarily on medications for chronic conditions such as diabetes and hypertension. The company operates courier services that facilitate the delivery of essential prescription medications across South Africa. By offering accessible solutions for medication distribution, Iyeza Health enables patients to conveniently collect and receive their chronic medications directly from public health facilities to their homes. This approach addresses the needs of individuals requiring ongoing treatment, ensuring they have reliable access to life-saving health products.
Qloudlab
Grant in 2019
Qloudlab is a pioneering company known for inventing the world's first touchscreen-based biosensor. The company has developed Sceptre, a modular platform that enables multiple diagnostics at the Point-of-Care through a single, mobile device capable of conducting various tests, including blood, urine, saliva, and skin analyses. This innovative technology bridges the gap between smartphones, healthcare, and cloud solutions, offering a cost-effective approach to diagnostics. Complementing this, Loop Medical focuses on revolutionizing blood collection by providing a needleless, pain-free technology. This device collects blood samples using a proprietary cartridge that integrates seamlessly with standard laboratory processes, enhancing the convenience for both patients and healthcare professionals. Together, these innovations represent a significant advancement in accessible and efficient medical diagnostics.
Butterfly Network
Series D in 2018
Butterfly Network develops innovative medical imaging devices designed to enhance point-of-care ultrasound programs in hospitals and healthcare organizations. Founded in 2011 and based in Guilford, Connecticut, the company has created the first handheld, single-probe whole-body ultrasound system, utilizing its patented Ultrasound-on-Chip technology. This compact device enables healthcare professionals to perform diagnostic imaging across various medical fields, including cardiology, urology, and obstetrics, all while integrating seamlessly into clinical workflows through mobile applications. Butterfly Network aims to democratize access to medical imaging, particularly for the 4.7 billion individuals globally who currently lack access to ultrasound, thereby promoting early detection and remote management of health conditions.
Recursion Pharmaceuticals
Grant in 2018
Recursion Pharmaceuticals is a clinical-stage biotechnology company based in Salt Lake City, Utah, focused on transforming drug discovery through the integration of technology, particularly artificial intelligence, automation, and bioinformatics. Founded in 2013, the company utilizes a sophisticated drug discovery platform that includes various software solutions and robotic automation to enhance chemical compound selection, streamline experimental workflows, and evaluate drug efficacy. Key components of this platform involve tools for designing chemical compounds, planning complex experiments, and analyzing data to understand drug interactions and biological responses. By creating one of the largest proprietary biological and chemical datasets, Recursion aims to uncover new biological insights and expedite the development of innovative treatments, ultimately improving patient outcomes.
Scripps Research
Grant in 2018
Scripps Research is a prominent independent, not-for-profit organization dedicated to advancing biomedical research aimed at enhancing human health. Established from the Scripps Metabolic Clinic in 1924, it has grown into one of the largest institutions of its kind, employing around 3,000 individuals across its campuses in La Jolla, California, and Jupiter, Florida. The institute is recognized for its significant contributions to the biomedical sciences, including the development of new treatments for various diseases such as cancer, rheumatoid arthritis, and hemophilia. Scripps Research is home to renowned scientists, including three Nobel laureates, who engage in cutting-edge research. Additionally, its graduate program in biology and chemistry is highly regarded, consistently ranking among the top ten programs in the United States.
Novartis
Grant in 2018
Novartis is a global healthcare company headquartered in Switzerland, dedicated to addressing the evolving needs of patients worldwide through the development and manufacturing of innovative pharmaceuticals. The company focuses on a wide range of therapeutic areas, including oncology, rare diseases, neuroscience, immunology, respiratory, and cardio-metabolic conditions. Novartis is also active in medical nutrition, providing specialized nutritional solutions for individuals with specific dietary needs. Additionally, its animal health division develops advanced medicines aimed at improving the health and welfare of pets, farm animals, and farmed fish. The Genomics Institute of the Novartis Research Foundation plays a crucial role in bridging basic science and preclinical drug discovery, employing nearly 600 scientists to enhance drug development processes. Through its diverse portfolio and commitment to research, Novartis aims to transform patient care and improve health outcomes globally.
NemoCare
Grant in 2017
NemoCare is developing the smartest and most comprehensive patient monitoring and management system. It is an innovative, continuous vital sign data acquisition, analysis and prediction engine that combines unobtrusive wireless wearable sensors and networks, analytical algorithms and big data to provide affordable continuous, high resolution monitoring for all newborns in hospital, and at home. We use design thinking principles to build life-saving technologies that will transform the way healthcare is delivered. Our current area of work is in newborn and maternal care.
Immunethep
Grant in 2017
Immunethep is a biotechnology company focused on developing innovative therapies for immune system-related diseases. Originating as a spin-off from the University of Porto, the company leverages proprietary technology to address significant unmet medical needs. Immunethep has identified a novel mechanism by which various pathogenic bacteria suppress the host immune response. By targeting this mechanism, the company aims to create broad-spectrum anti-bacterial immunotherapies. Among its initiatives, Immunethep is working on neonatal vaccines designed to protect infants from bacterial infections before birth, thereby enhancing their immunity and preventing multi-bacterial infections. Through these advancements, Immunethep strives to improve patient outcomes and contribute to the field of advanced healthcare.
Simprints
Grant in 2017
Simprints is a nonprofit technology company focused on enhancing global development efforts to alleviate poverty. It develops mobile biometric scanner software and identification tools that provide an affordable and secure fingerprint system designed for challenging environments. Simprints' solutions enable healthcare workers in remote areas to access patient records digitally through a mobile device, thus improving the efficiency and effectiveness of healthcare delivery. By ensuring that resources like vaccines and public goods reach those who need them most, Simprints aims to increase transparency and accountability in the distribution of aid and services.
Qloudlab
Grant in 2017
Qloudlab is a pioneering company known for inventing the world's first touchscreen-based biosensor. The company has developed Sceptre, a modular platform that enables multiple diagnostics at the Point-of-Care through a single, mobile device capable of conducting various tests, including blood, urine, saliva, and skin analyses. This innovative technology bridges the gap between smartphones, healthcare, and cloud solutions, offering a cost-effective approach to diagnostics. Complementing this, Loop Medical focuses on revolutionizing blood collection by providing a needleless, pain-free technology. This device collects blood samples using a proprietary cartridge that integrates seamlessly with standard laboratory processes, enhancing the convenience for both patients and healthcare professionals. Together, these innovations represent a significant advancement in accessible and efficient medical diagnostics.
Vaxess Technologies
Grant in 2017
Vaxess Technologies, Inc. is a biotechnology company based in Boston, Massachusetts, founded in 2011. The company focuses on developing and commercializing innovative silk biomaterial technologies. Its key product, the MIMIX microneedle platform, facilitates the transdermal delivery of vaccines and therapeutics. This sustained release patch technology allows for a controlled release of vaccines, mimicking the natural infection process to enhance immune response and effectiveness. Vaxess's patch is engineered for stability, eliminating the need for refrigeration, which enables shipping and application in low-resource settings. In addition to its vaccine delivery systems, Vaxess is also engaged in creating novel therapies aimed at oncology care and infectious diseases, ultimately striving to improve patient outcomes with reduced treatment burdens.
Vir Biotechnology
Venture Round in 2017
Vir Biotechnology, Inc. is a clinical-stage immunology company based in San Francisco, California, that focuses on developing therapeutic products aimed at treating and preventing serious infectious diseases. The company is working on several key therapies, including VIR-2218 and VIR-3434 for hepatitis B, VIR-2482 for influenza A, VIR-1111 for human immunodeficiency virus, and VIR-2020 for tuberculosis. Vir Biotechnology employs advanced technologies and scientific expertise to manipulate immune responses and enhance pathogen-host interactions. The company has established collaborations and agreements with various organizations, including the Bill & Melinda Gates Foundation, National Institutes of Health, Brii Biosciences, Alnylam Pharmaceuticals, and others, to further its research and development efforts. Additionally, it has a manufacturing agreement with Samsung Biologics for producing antibodies related to COVID-19 treatments. Founded in 2016, Vir Biotechnology aims to leverage its innovative platforms to potentially eradicate diseases like hepatitis B, influenza A, HIV, and tuberculosis.
Univercells
Grant in 2016
Univercells is a provider of biomanufacturing solutions focused on making biologics, including vaccines and therapeutics, more accessible and affordable. The company offers innovative technologies designed to reduce manufacturing costs significantly, achieving up to 90% savings on the cost of goods and over 75% in capital investment. Their approach utilizes single-use technologies and integrates three manufacturing steps—cell culture under perfusion, clarification, and capture—into a simulated continuous mode. Univercells also provides a range of biomanufacturing services, including scale-X hydro, scale-X carbo, and NevoLine, along with integrated support such as equipment confirmation, facility design, and bioprocess excellence. This comprehensive offering aids cell and gene therapy manufacturers in scaling their operations from research and development to commercial production, ultimately addressing global health challenges.
AgBiome
Grant in 2016
AgBiome, LLC is a biotechnology company based in Durham, North Carolina, that focuses on developing biological products to address significant challenges in agriculture, particularly soil-borne diseases affecting greenhouse and major row crops. Utilizing advanced genomics and screening technologies, AgBiome identifies plant-associated microbes that can enhance plant health, improve pest resistance, and increase crop yields. The company operates a state-of-the-art laboratory and greenhouse facility and collaborates with prominent agricultural firms to expedite its research and product development. AgBiome's offerings include fungicides that protect crops from various diseases and a platform for capturing and screening diverse microbes for agricultural applications. Established in 2012, AgBiome aims to provide sustainable solutions that support global food production and address critical agricultural issues such as insect and nematode control.
Masimo
Grant in 2016
Masimo Corporation, founded in 1989 and based in Irvine, California, is a medical technology company specializing in non-invasive patient monitoring solutions. The company is renowned for its pulse oximetry technology, notably Masimo Signal Extraction Technology® (SET®), which improves the reliability of blood oxygen measurements, especially in challenging conditions such as patient motion or low perfusion. The technology originated from the founder's observations in neonatal care and has evolved to include a range of advanced monitoring devices and solutions, such as the Root® platform, Masimo Patient SafetyNet™, and the Masimo Stork™ baby monitor. Masimo's product lineup also features noninvasive measurements for various physiological parameters, therapeutic devices like Masimo softFlow™, and wearable health tracking solutions such as the Masimo W1™ watch. The company markets its products directly to healthcare providers and through distributors, as well as collaborating with original equipment manufacturers to integrate its technologies into broader healthcare solutions.
Atomo Diagnostics
Grant in 2016
Atomo Diagnostics was established to capitalize on a core belief that health care products offering significantly improved levels of convenience, simplicity and user experience are disproportionately disruptive and have the potential to be very successful commercial market entrants. Having identified the usability challenges and in-field limitations of existing RDT products, Atomo worked closely with healthcare workers and consumers in a range of settings and determined that by integrating all the test components into a streamlined, end-to-end solution it could significantly improve safety and accuracy and reduce user error rates. This focus on usability and how end users interact with the RDT is one of the key aspects that sets Atomo apart from its competition in the POCT market. Its unique design and patented features mean that AtomoRapid™ addresses and eliminates the vast majority of user errors identified as impacting the performance of standard RDTs in the field. AtomoRapid™ makes it easy to convert proven diagnostic technologies into user-friendly products that deliver unmatched customer satisfaction and in-field performance. These products are successful due to their ability to materially improve usability, convenience, and reliability for both professional and home users. It is this unswerving focus on exceeding user expectations that the management team has applied to the diagnostic market; a market that has to date seen little user-centric innovation. Atomo Diagnostics is headquartered in Sydney, Australia, with corporate offices located in South Africa the UK. The company is led by an executive team with a track record of success commercializing disruptive healthcare products, and the company has assembled an experienced and committed international management team and Board and advisors.
Takeda
Grant in 2016
Takeda Pharmaceutical Company Limited is a global biopharmaceutical leader that focuses on researching, developing, manufacturing, and marketing innovative medicines. The company specializes in a range of therapeutic areas, including oncology, gastroenterology, neuroscience, and rare diseases. With its commitment to improving patient outcomes, Takeda is dedicated to delivering advanced pharmaceuticals and therapeutics, as well as vaccines. Founded in 1781 and headquartered in Japan, Takeda operates worldwide, with significant research and development facilities in locations such as Cambridge, Massachusetts, and San Diego, California. The company also engages in strategic investments through its venture capital arm, which supports early-stage companies and technologies that align with its therapeutic focus, fostering collaborations that leverage its extensive R&D capabilities. Takeda's mission is to enhance the quality of life for patients globally through continuous innovation and excellence in healthcare.
Affinivax
Series A in 2016
Affinivax, Inc. is a biotechnology company based in Lexington, Massachusetts, focused on developing innovative vaccines using its proprietary Multiple Antigen Presenting System (MAPS) technology. This approach allows for the combination of protective polysaccharides and proteins into a single vaccine, thereby enhancing immune responses against a variety of infectious diseases affecting both children and adults. Affinivax targets several significant pathogens, including Streptococcus pneumoniae, bacterial nosocomial infections, Salmonella typhi, and Staphylococcus aureus. The company aims to create vaccines that not only provide broader disease coverage compared to existing options but also address infectious diseases lacking effective immunization strategies. Founded in 2014, Affinivax benefits from the expertise of leading professionals in infectious diseases and vaccines, and it has received backing from the Bill & Melinda Gates Foundation, along with an exclusive license from Boston Children’s Hospital for its MAPS technology.
Moderna
Grant in 2016
Moderna, Inc. is a biotechnology company based in Cambridge, Massachusetts, that specializes in developing therapeutics and vaccines using messenger RNA technology. Founded in 2010, the company focuses on various therapeutic areas, including infectious diseases, oncology, rare genetic disorders, and cardiovascular diseases. As of September 2024, Moderna has 40 mRNA development candidates in clinical development, demonstrating its commitment to advancing medical science. The company's mRNA platform has gained significant recognition, particularly with the authorization of its COVID-19 vaccine in December 2020. Moderna has established strategic collaborations with notable organizations such as AstraZeneca, Merck & Co., and the Bill & Melinda Gates Foundation. Additionally, it collaborates with Lonza Ltd. and Catalent for the manufacturing of its COVID-19 vaccine. Through its innovative approach, Moderna aims to provide effective solutions for a range of health challenges.
Lodo Therapeutics
Series A in 2016
Lodo Therapeutics Corporation is a drug discovery and development company focused on the creation of naturally derived novel therapeutics that will have a dramatic impact human health on a global basis. Lodo seeks to work in partnership with global pharmaceutical companies and world leading Non-Governmental Organizations (NGO’s) to tackle some of the greatest challenges in human health: resistant infectious disease and cancers. Lodo Therapeutics was created to pursue the scientific vision of Dr. Sean Brady at Rockefeller University. Dr. Brady and his laboratory have developed a genome-based, culture-independent platform for the discovery, biosynthesis, and characterization of small molecules from microbial sources present in soil samples. Lodo believes that the potential cures for a number of deadly and/or debilitating diseases literally lie at our feet. By combining the advancements in DNA sequencing and bioinformatics, this innovative discovery platform exploits the power of microbial evolution for the identification of therapeutically valuable pharmaceutical products derived from natural sources. Lodo Therapeutics, an Accelerator Corporation-backed entity, is headquartered in New York City. The company’s lab and offices are located in the Alexandria Center for Life Science, New York City’s first and only premier life science park.
In2Care
Grant in 2015
In2Care is a company focused on developing innovative mosquito traps to combat diseases transmitted by mosquitoes, such as malaria. Their products are designed to provide personal protection from mosquito bites while aiding pest controllers in managing mosquito populations. The traps feature built-in ventilation tubes and mosquito-killing gauze inserts, enhancing their effectiveness. In2Care's work is grounded in academic research and has received endorsement from notable organizations, including the Bill & Melinda Gates Foundation and the UBS Optimus Foundation. The company has also been supported by local initiatives like StartLife and PPM Oost/Gelderland voor Innovaties, underscoring its commitment to transparency and collaboration in addressing public health challenges.
CureVac
Series F in 2015
CureVac is a clinical-stage biopharmaceutical company based in Germany, focused on developing vaccines and therapies utilizing messenger RNA (mRNA). Founded in 2000, the company’s innovative approach involves using mRNA as a data carrier to instruct the body to produce proteins that can combat various diseases. CureVac's pipeline includes novel mRNA-based cancer immunotherapies, prophylactic vaccines for infectious diseases, and molecular therapies aimed at enhancing the body’s production of therapeutic proteins. Its most advanced candidate, CV9104, is currently in Phase IIb clinical trials for prostate cancer treatment. Additionally, CureVac has collaborated with GSK to create second-generation vaccines for seasonal influenza and COVID-19, as well as an avian influenza vaccine, while exploring other mRNA vaccine applications in oncology and various therapeutic areas.
AgBiome
Series B in 2015
AgBiome, LLC is a biotechnology company based in Durham, North Carolina, that focuses on developing biological products to address significant challenges in agriculture, particularly soil-borne diseases affecting greenhouse and major row crops. Utilizing advanced genomics and screening technologies, AgBiome identifies plant-associated microbes that can enhance plant health, improve pest resistance, and increase crop yields. The company operates a state-of-the-art laboratory and greenhouse facility and collaborates with prominent agricultural firms to expedite its research and product development. AgBiome's offerings include fungicides that protect crops from various diseases and a platform for capturing and screening diverse microbes for agricultural applications. Established in 2012, AgBiome aims to provide sustainable solutions that support global food production and address critical agricultural issues such as insect and nematode control.
Ceres Nano
Grant in 2015
Ceres Nanosciences Inc. is a privately held life sciences company focused on the development and commercialization of innovative sample preparation products utilizing its proprietary Nanotrap® technology. This technology captures, enriches, and preserves analytes and biomarkers, which is essential for the early detection of diseases such as cancer, cardiac conditions, and infectious diseases. By facilitating the identification of low abundance biomarkers, Ceres aims to enhance diagnostic accuracy and improve patient outcomes while potentially reducing healthcare costs. The company has a diverse product pipeline that includes advanced sample collection technologies and diagnostics, supported by federal grants and industry collaborations. Among its key developments is a direct antigen test for Lyme disease, which is anticipated to be available for commercial use.
CureVac
Series E in 2015
CureVac is a clinical-stage biopharmaceutical company based in Germany, focused on developing vaccines and therapies utilizing messenger RNA (mRNA). Founded in 2000, the company’s innovative approach involves using mRNA as a data carrier to instruct the body to produce proteins that can combat various diseases. CureVac's pipeline includes novel mRNA-based cancer immunotherapies, prophylactic vaccines for infectious diseases, and molecular therapies aimed at enhancing the body’s production of therapeutic proteins. Its most advanced candidate, CV9104, is currently in Phase IIb clinical trials for prostate cancer treatment. Additionally, CureVac has collaborated with GSK to create second-generation vaccines for seasonal influenza and COVID-19, as well as an avian influenza vaccine, while exploring other mRNA vaccine applications in oncology and various therapeutic areas.
Genocea Biosciences
Grant in 2014
Genocea Biosciences is a biopharmaceutical company based in Cambridge, Massachusetts, focused on the discovery and development of innovative cancer immunotherapies and vaccines. Utilizing its proprietary ATLAS platform, the company profiles patients' CD4+ and CD8+ T cell immune responses to identify potential antigens in tumors. Genocea is advancing several immuno-oncology programs, including GEN-009, an adjuvanted neoantigen peptide vaccine currently in phase I/IIa clinical trials, and GEN-011, a neoantigen adoptive T cell therapy. Additionally, the company has developed GEN-003, an immunotherapy aimed at treating genital herpes, and is working on personalized cancer vaccines through its pre-clinical immuno-oncology program. Established in 2006, Genocea aims to address significant unmet medical needs with its targeted therapeutic approaches.
Oregon Health & Science University
Grant in 2014
Oregon Health & Science University is dedicated to improving the health and quality of life for all Oregonians through excellence, innovation and leadership in health care, education and research. OHSU is the kind of place where the big news doesn't always involve sports, politics, fashion or even weather. The big news is always about health — health care, health education, health-related research. And various organizations and publications that rank American institutions, programs and faculty in a variety of categories have taken note. Nearly one million patient visits each year. Educating thousands of future health care providers. You get the picture. Immerse yourself in more facts and stats than you probably need about Portland's largest employer, Oregon's provider of care to every corner of the state, and one of the nation's top 28 biomedical research institutions. Oregon Health & Science University is the state’s only academic health center. It provides an uncommon array of services from providing the state’s most comprehensive health care, to educating the next generation of clinicians and biomedical researchers, to achieving breakthroughs and innovations.
SomaLogic
Grant in 2014
SomaLogic, Inc. is a commercial-stage company based in Boulder, Colorado, specializing in protein biomarker discovery and clinical diagnostics. The company utilizes its proprietary technology platform, SomaScan, which allows for the measurement of proteins with a precision comparable to DNA measurement. This technology enhances the understanding of the molecular bases of health and disease, surpassing traditional genomic methods. SomaLogic develops and offers SOMAmers, modified nucleic acid-based protein-binding reagents, and provides diagnostic tests and protein measurement solutions for various diseases, including those in oncology, neurology, and cardiovascular health. Their products serve multiple applications, including life sciences research, therapeutic drug development, and clinical diagnostics, making significant contributions to the fields of biological and medical sciences. Founded in 1999, SomaLogic continues to advance the capabilities of proteomics in both research and clinical settings.
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