ARCH Venture Partners

Moleculent is a biotechnology company focused on advancing human health through technology-enabled products that utilize insights into the molecular basis of human biology. The company is dedicated to decoding human biology and aims to significantly enhance therapies and diagnostics by leveraging new scientific knowledge. Moleculent believes that a deeper understanding of molecular mechanisms, especially in relation to health and disease, will emerge over the next decade, paving the way for innovative healthcare solutions. Through its efforts, the company seeks to provide healthcare professionals with access to molecular science-based therapies and diagnostics that can improve patient care and outcomes.

Slingshot Biosciences, Inc. is a biotechnology company based in Emeryville, California, specializing in the development of engineered synthetic cells for diagnostics and therapeutics. Founded in 2012, the company operates within the industrial synthetic biology sector, focusing on delivering innovative solutions that address challenges in research and development. Slingshot Biosciences aims to provide cost-effective and straightforward approaches to enhance drug research by enabling precise measurement and standardization in cell analysis. Their technology eliminates the need for cold-chain storage, facilitating access to advanced diagnostics and therapeutics, particularly for neglected and rare diseases.

Metsera is a clinical-stage biopharmaceutical company dedicated to developing innovative therapies for obesity and metabolic conditions. The company focuses on advancing a variety of treatment options, including both oral and injectable therapies, specifically targeting incretin, non-incretin, and combination approaches. By integrating proprietary health technology tools, Metsera aims to provide personalized care that meets the evolving demands of weight loss treatment. Its commitment to addressing multiple therapeutic targets positions the company to significantly impact the future of obesity management and related metabolic diseases.

Metsera is a clinical-stage biopharmaceutical company dedicated to developing innovative therapies for obesity and metabolic conditions. The company focuses on advancing a variety of treatment options, including both oral and injectable therapies, specifically targeting incretin, non-incretin, and combination approaches. By integrating proprietary health technology tools, Metsera aims to provide personalized care that meets the evolving demands of weight loss treatment. Its commitment to addressing multiple therapeutic targets positions the company to significantly impact the future of obesity management and related metabolic diseases.

Accompany Health is a health technology company dedicated to providing comprehensive in-home care to patients, particularly in underserved regions. The organization focuses on delivering primary care services, including chronic illness management and treatment for new symptoms. By facilitating the organization and coordination of care, Accompany Health aims to alleviate the common challenges faced by patients, such as long wait times and complex healthcare navigation. The company emphasizes building long-term relationships with the individuals they serve, ensuring that patients receive continuous support and care around the clock. Their approach prioritizes dignity and accessibility, catering especially to low-income patients with complex healthcare needs through both at-home and virtual care solutions.

Elephas is a company focused on revolutionizing cancer treatment through its innovative live tumor imaging diagnostics platform. By leveraging advances in cancer biology, multimodal microscopy, engineering, and artificial intelligence, Elephas aims to enhance clinical decision-making and personalize therapy for cancer patients. The company's approach involves the use of human live tumor fragments, allowing clinicians to determine the most effective treatment strategies for individual patients. In doing so, Elephas not only seeks to improve patient outcomes but also to expedite the drug development process, addressing the significant challenges faced in oncology.

UltraDx Bio is a biotechnology company that specializes in single-molecule digital high-sensitivity protein detection technology.

Slingshot Biosciences, Inc. is a biotechnology company based in Emeryville, California, specializing in the development of engineered synthetic cells for diagnostics and therapeutics. Founded in 2012, the company operates within the industrial synthetic biology sector, focusing on delivering innovative solutions that address challenges in research and development. Slingshot Biosciences aims to provide cost-effective and straightforward approaches to enhance drug research by enabling precise measurement and standardization in cell analysis. Their technology eliminates the need for cold-chain storage, facilitating access to advanced diagnostics and therapeutics, particularly for neglected and rare diseases.

Paradigm is rebuilding the clinical research ecosystem by developing a platform that allows all patients equitable access to trials while improving trial efficiency and lowering barriers to participation for healthcare providers. It is an innovative company that is dedicated to transforming the clinical research ecosystem. Their mission is to create a more accessible and equitable healthcare system by developing a platform that enables patients from diverse backgrounds to participate in clinical trials. Clinical trials are essential for testing and developing new drugs, therapies, and medical devices, but historically, they have been plagued by inefficiencies, barriers to access, and inequities in patient representation. Paradigm aims to solve these challenges by creating a platform that uses technology and data-driven insights to streamline the clinical trial process, making it more efficient, cost-effective, and inclusive. The Paradigm platform is designed to facilitate seamless communication and collaboration among all stakeholders involved in clinical research, including patients, healthcare providers, pharmaceutical companies, and regulatory agencies. By leveraging technology such as AI, machine learning, and predictive analytics, Paradigm can identify and match eligible patients to clinical trials, streamline the recruitment and enrollment process, and provide real-time data insights to all stakeholders. Overall, Paradigm's innovative approach to clinical research has the potential to revolutionize the healthcare industry by improving patient outcomes, reducing healthcare costs, and accelerating the development of new treatments and therapies.

Elephas is a company focused on revolutionizing cancer treatment through its innovative live tumor imaging diagnostics platform. By leveraging advances in cancer biology, multimodal microscopy, engineering, and artificial intelligence, Elephas aims to enhance clinical decision-making and personalize therapy for cancer patients. The company's approach involves the use of human live tumor fragments, allowing clinicians to determine the most effective treatment strategies for individual patients. In doing so, Elephas not only seeks to improve patient outcomes but also to expedite the drug development process, addressing the significant challenges faced in oncology.

Happy Health is a mission-driven technology company committed to transforming mental health awareness through the Happy Ring, the first wearable designed to measure your stress and mood 24/7.

Homeward is a healthcare services provider focused on improving access to quality care for the 60 million Americans living in rural communities. The company employs a multidisciplinary care team that operates both in-home and through mobile care units, utilizing technology for remote monitoring. This approach aims to connect patients with high-quality, affordable care, particularly for Medicare-eligible beneficiaries. Homeward partners with Medicare Advantage plans and assumes full financial risk for the care of its members, with the objective of enhancing health outcomes while reducing costs.

Proof Diagnostics is a life sciences company focused on developing diagnostic tools and therapeutic applications. The company specializes in creating rapid diagnostic tests for infectious diseases, including a critical test for the detection of coronavirus infection. With a commitment to enhancing patient care, Proof Diagnostics designs and manufactures diagnostic kits that empower medical professionals to accurately and efficiently test patients for various infections. Additionally, the company is working on a smart, portable system aimed at expanding the capabilities of disease detection.

Singleron Biotechnologies Ltd. is a molecular diagnostic company specializing in single cell sequencing solutions. Founded in 2018 and based in Nanjing, China, with additional offices and laboratories in Suzhou, the United States, and Germany, the firm develops a range of innovative products, including the Singleron Matrix automated instrument for high-density microwell processing and GEXSCOPE single cell RNA sequencing kits. The company also offers a microfluidic chip for cell partitioning, magnetic beads for cell barcoding, and tools for data analysis such as CeleScope and SynEcoSys, which facilitate the interpretation of single cell sequencing data. Singleron provides services in single cell RNA sequencing, single nucleus RNA sequencing, and bioinformatics analysis, aiming to advance clinical diagnosis, drug development, and health management. The company collaborates with research institutes, hospitals, and pharmaceutical firms primarily in China and the United States, leveraging its exclusive IP license from Yale University to enhance its innovative capabilities in single cell analysis.

Slingshot Biosciences, Inc. is a biotechnology company based in Emeryville, California, specializing in the development of engineered synthetic cells for diagnostics and therapeutics. Founded in 2012, the company operates within the industrial synthetic biology sector, focusing on delivering innovative solutions that address challenges in research and development. Slingshot Biosciences aims to provide cost-effective and straightforward approaches to enhance drug research by enabling precise measurement and standardization in cell analysis. Their technology eliminates the need for cold-chain storage, facilitating access to advanced diagnostics and therapeutics, particularly for neglected and rare diseases.

Interline Therapeutics is a drug discovery company based in South San Francisco, California, founded in 2020 by Zach Sweeney. The company specializes in mapping and correcting dysfunctional protein communities to address molecular mechanisms of disease. By utilizing advancements in genomics, proteomics, structural biology, and computational chemistry, Interline has developed a precision medicine platform that focuses on three key areas: genomics, communities, and modulators. This approach enables the identification of new medicines targeting genetically validated signaling pathways, ensuring that drug candidates effectively correct dysfunctional disease networks. Through collaborations with leading academic groups, Interline aims to enhance its capabilities in drug discovery and development.

Ultivue, Inc. is a biotechnology company based in Cambridge, Massachusetts, specializing in the development and manufacturing of reagents for marker multiplexing detection and analysis. Founded in 2015, the company focuses on tissue imaging, diagnostics, and multiplexing to enhance research in the life sciences and biomedical fields. Ultivue's innovative technologies, including DNA-PAINT and DNA-Exchange, facilitate the collection of high-resolution microscopic images that contribute to a deeper understanding of biological processes and diseases. The company’s multiplex biomarker assays are designed for tissue phenotyping and digital pathology, integrating validated antibodies and advanced analytics to support personalized medicine. Ultivue's products are intended for fluorescent microscopy-based research and hold potential for clinical diagnostic applications.

Jaguar Gene Therapy is a clinical-stage biotechnology company focused on accelerating breakthroughs in gene therapy for patients suffering from severe genetic diseases. The company specializes in developing treatments that target nonworking or missing genes by introducing healthy copies back into the body to restore function. This approach aims to address significant unmet needs in healthcare by expediting the development of gene therapies from research to clinical application as safely and quickly as possible.

Interline Therapeutics is a drug discovery company based in South San Francisco, California, founded in 2020 by Zach Sweeney. The company specializes in mapping and correcting dysfunctional protein communities to address molecular mechanisms of disease. By utilizing advancements in genomics, proteomics, structural biology, and computational chemistry, Interline has developed a precision medicine platform that focuses on three key areas: genomics, communities, and modulators. This approach enables the identification of new medicines targeting genetically validated signaling pathways, ensuring that drug candidates effectively correct dysfunctional disease networks. Through collaborations with leading academic groups, Interline aims to enhance its capabilities in drug discovery and development.

Singleron Biotechnologies Ltd. is a molecular diagnostic company specializing in single cell sequencing solutions. Founded in 2018 and based in Nanjing, China, with additional offices and laboratories in Suzhou, the United States, and Germany, the firm develops a range of innovative products, including the Singleron Matrix automated instrument for high-density microwell processing and GEXSCOPE single cell RNA sequencing kits. The company also offers a microfluidic chip for cell partitioning, magnetic beads for cell barcoding, and tools for data analysis such as CeleScope and SynEcoSys, which facilitate the interpretation of single cell sequencing data. Singleron provides services in single cell RNA sequencing, single nucleus RNA sequencing, and bioinformatics analysis, aiming to advance clinical diagnosis, drug development, and health management. The company collaborates with research institutes, hospitals, and pharmaceutical firms primarily in China and the United States, leveraging its exclusive IP license from Yale University to enhance its innovative capabilities in single cell analysis.

Glympse Bio, Inc. is a biotechnology company based in Cambridge, Massachusetts, that specializes in developing modular nanoparticle sensors for noninvasive diagnostics. Founded in 2015, the company focuses on creating diagnostic solutions for various diseases, including fibrosis, cancer, immunology, and infectious diseases. Utilizing a unique platform technology originally developed at MIT, Glympse Bio employs precisely engineered diagnostic agents that interrogate the body to detect specific disease states and transmit this information to urine for analysis. This innovative approach facilitates predictive monitoring and enhances the ability of physicians to assess treatment responses accurately. The company aims to transform disease monitoring and improve patient outcomes through its Glympse Inside product engine, which supports comprehensive, pan-disease diagnostics.

One BioMed is a molecular life science company focused on advancing human health through innovative biomedical research, products, and testing solutions. The company specializes in developing a diagnostics testing platform that facilitates the purification and isolation of nucleic acids from diverse samples. Its offerings include DNA and RNA cartridge kits, which are integral to its platform that integrates molecular diagnostic tools. Utilizing proprietary silicon biophotonics sensing technology, One BioMed enables healthcare professionals to detect point-of-care infectious diseases efficiently and effectively. Through its commitment to innovation, the company aims to enhance diagnostic capabilities in the medical field.

Ultivue, Inc. is a biotechnology company based in Cambridge, Massachusetts, specializing in the development and manufacturing of reagents for marker multiplexing detection and analysis. Founded in 2015, the company focuses on tissue imaging, diagnostics, and multiplexing to enhance research in the life sciences and biomedical fields. Ultivue's innovative technologies, including DNA-PAINT and DNA-Exchange, facilitate the collection of high-resolution microscopic images that contribute to a deeper understanding of biological processes and diseases. The company’s multiplex biomarker assays are designed for tissue phenotyping and digital pathology, integrating validated antibodies and advanced analytics to support personalized medicine. Ultivue's products are intended for fluorescent microscopy-based research and hold potential for clinical diagnostic applications.

LunaPBC, Inc. is a Public Benefit Corporation based in San Diego, California, focused on developing a community-owned platform for health and DNA research. The company's primary offering is LunaDNA, a genomic and medical research knowledge database that enables individuals to share their health and DNA data for research purposes. This platform facilitates collaborations with pharmaceutical companies, insurance providers, and healthcare IT organizations to drive advancements in medical discoveries. By allowing members to contribute their health data, LunaPBC not only supports vital health research projects but also ensures that participants can share in the financial benefits arising from medical breakthroughs, fostering a sense of community ownership and engagement in the research process.

LunaDNA is a community-owned genomic and medical research platform founded by the creators of a leading DNA sequencing company. It facilitates the sharing of health and DNA data, allowing individuals to contribute their personal information for medical research while maintaining ownership of their data. By incentivizing participation, LunaDNA addresses the challenge of data silos that have emerged as personal DNA sequencing has gained popularity. Participants are rewarded with shares in the database, granting them a stake in the profits generated from medical research. These profits are returned to the community as dividends when researchers pay for access to the data. LunaDNA empowers individuals to support health research while ensuring that their contributions benefit the broader community and drive medical discoveries.

Glympse Bio, Inc. is a biotechnology company based in Cambridge, Massachusetts, that specializes in developing modular nanoparticle sensors for noninvasive diagnostics. Founded in 2015, the company focuses on creating diagnostic solutions for various diseases, including fibrosis, cancer, immunology, and infectious diseases. Utilizing a unique platform technology originally developed at MIT, Glympse Bio employs precisely engineered diagnostic agents that interrogate the body to detect specific disease states and transmit this information to urine for analysis. This innovative approach facilitates predictive monitoring and enhances the ability of physicians to assess treatment responses accurately. The company aims to transform disease monitoring and improve patient outcomes through its Glympse Inside product engine, which supports comprehensive, pan-disease diagnostics.

AgBiome, LLC is a biotechnology company based in Durham, North Carolina, that focuses on the agriculture industry through the development of biological products. Founded in 2012, AgBiome leverages its expertise in plant-associated microbes and modern genomics to create innovative solutions aimed at enhancing plant health, pest resistance, and crop yields. The company addresses critical agricultural challenges, including soil-borne diseases, insects, and nematodes, by offering fungicides and a platform that identifies and screens diverse microbial strains. AgBiome collaborates with prominent agricultural partners to accelerate discovery processes and broaden the reach of its sustainable products in global markets. With a dedicated team of over 85 employees and a state-of-the-art laboratory and greenhouse facility, AgBiome is committed to improving food production responsibly.

LunaDNA is a community-owned genomic and medical research platform founded by the creators of a leading DNA sequencing company. It facilitates the sharing of health and DNA data, allowing individuals to contribute their personal information for medical research while maintaining ownership of their data. By incentivizing participation, LunaDNA addresses the challenge of data silos that have emerged as personal DNA sequencing has gained popularity. Participants are rewarded with shares in the database, granting them a stake in the profits generated from medical research. These profits are returned to the community as dividends when researchers pay for access to the data. LunaDNA empowers individuals to support health research while ensuring that their contributions benefit the broader community and drive medical discoveries.

Ultivue, Inc. is a biotechnology company based in Cambridge, Massachusetts, specializing in the development and manufacturing of reagents for marker multiplexing detection and analysis. Founded in 2015, the company focuses on tissue imaging, diagnostics, and multiplexing to enhance research in the life sciences and biomedical fields. Ultivue's innovative technologies, including DNA-PAINT and DNA-Exchange, facilitate the collection of high-resolution microscopic images that contribute to a deeper understanding of biological processes and diseases. The company’s multiplex biomarker assays are designed for tissue phenotyping and digital pathology, integrating validated antibodies and advanced analytics to support personalized medicine. Ultivue's products are intended for fluorescent microscopy-based research and hold potential for clinical diagnostic applications.

ImmusanT, Inc. is a biotechnology company based in Cambridge, Massachusetts, focused on developing therapies and diagnostics for celiac disease. Founded in 2010, the company aims to restore immune tolerance to gluten in patients with this autoimmune disorder. Its primary product, Nexvax2, is a therapeutic vaccine designed to treat, prevent, and diagnose celiac disease. Additionally, ImmusanT is working on a functional T-cell test to facilitate the diagnosis and monitoring of immune tolerance in patients undergoing peptide-based therapy. Through its innovative approach, the company seeks to enhance the management of celiac disease and potentially other autoimmune conditions.

Unity Biotechnology, Inc. is a biotechnology company dedicated to the research and development of therapeutics aimed at extending human health span by addressing age-related diseases. The company specializes in clearing senescent cells through the creation of senolytic medicines, which specifically target vulnerabilities unique to these cells while sparing healthy ones. Its lead drug candidates include UBX0101, currently in Phase II clinical trials for musculoskeletal conditions like osteoarthritis, and UBX1325, which is in Phase I trials for diabetic macular edema. Additionally, Unity is developing treatments for various conditions related to aging, including pulmonary and neurological disorders, as well as kidney and liver diseases. Founded in 2009 and headquartered in South San Francisco, California, Unity Biotechnology was previously known as Forge, Inc. before changing its name in 2015.

VBI Vaccines Inc. is a biopharmaceutical company based in Cambridge, Massachusetts, with research facilities in Ottawa, Canada. It develops and sells vaccines for infectious diseases and immuno-oncology, with a focus on expanding protection in large, underserved markets. The company's enveloped virus-like particle (eVLP) platform enables the creation of vaccines that closely mimic target viruses, eliciting potent immune responses. VBI's commercial product, Sci-B-Vac, is a hepatitis B vaccine approved in Israel and 14 other countries, offering rapid onset of protection and high antibody levels. The company is also developing VBI-2601 for a functional cure of chronic hepatitis B, VBI-1901 for glioblastoma, and VBI-1501 for cytomegalovirus, among other candidates. VBI collaborates with pharmaceutical companies and research institutions, and its products are primarily distributed through direct sales to physicians and pharmacists.

Lodo Therapeutics Corporation is a drug discovery and development company dedicated to creating novel therapeutics derived from natural sources. It focuses on addressing significant health challenges, particularly resistant infectious diseases and cancers, by collaborating with global pharmaceutical companies and leading non-governmental organizations. Founded to realize the scientific vision of Dr. Sean Brady from Rockefeller University, Lodo Therapeutics utilizes a genome-based, culture-independent platform to discover and characterize small molecules sourced from environmental microbial DNA. This innovative approach leverages advancements in DNA sequencing and bioinformatics to explore the untapped potential of microbial evolution, aiming to identify therapeutically valuable pharmaceutical products. Headquartered in New York City at the Alexandria Center for Life Science, Lodo Therapeutics is committed to harnessing the power of nature in the fight against undruggable targets and high unmet medical needs.

Ultivue, Inc. is a biotechnology company based in Cambridge, Massachusetts, specializing in the development and manufacturing of reagents for marker multiplexing detection and analysis. Founded in 2015, the company focuses on tissue imaging, diagnostics, and multiplexing to enhance research in the life sciences and biomedical fields. Ultivue's innovative technologies, including DNA-PAINT and DNA-Exchange, facilitate the collection of high-resolution microscopic images that contribute to a deeper understanding of biological processes and diseases. The company’s multiplex biomarker assays are designed for tissue phenotyping and digital pathology, integrating validated antibodies and advanced analytics to support personalized medicine. Ultivue's products are intended for fluorescent microscopy-based research and hold potential for clinical diagnostic applications.

AgBiome, LLC is a biotechnology company based in Durham, North Carolina, that focuses on the agriculture industry through the development of biological products. Founded in 2012, AgBiome leverages its expertise in plant-associated microbes and modern genomics to create innovative solutions aimed at enhancing plant health, pest resistance, and crop yields. The company addresses critical agricultural challenges, including soil-borne diseases, insects, and nematodes, by offering fungicides and a platform that identifies and screens diverse microbial strains. AgBiome collaborates with prominent agricultural partners to accelerate discovery processes and broaden the reach of its sustainable products in global markets. With a dedicated team of over 85 employees and a state-of-the-art laboratory and greenhouse facility, AgBiome is committed to improving food production responsibly.

Unity Biotechnology, Inc. is a biotechnology company dedicated to the research and development of therapeutics aimed at extending human health span by addressing age-related diseases. The company specializes in clearing senescent cells through the creation of senolytic medicines, which specifically target vulnerabilities unique to these cells while sparing healthy ones. Its lead drug candidates include UBX0101, currently in Phase II clinical trials for musculoskeletal conditions like osteoarthritis, and UBX1325, which is in Phase I trials for diabetic macular edema. Additionally, Unity is developing treatments for various conditions related to aging, including pulmonary and neurological disorders, as well as kidney and liver diseases. Founded in 2009 and headquartered in South San Francisco, California, Unity Biotechnology was previously known as Forge, Inc. before changing its name in 2015.

AgBiome, LLC is a biotechnology company based in Durham, North Carolina, that focuses on the agriculture industry through the development of biological products. Founded in 2012, AgBiome leverages its expertise in plant-associated microbes and modern genomics to create innovative solutions aimed at enhancing plant health, pest resistance, and crop yields. The company addresses critical agricultural challenges, including soil-borne diseases, insects, and nematodes, by offering fungicides and a platform that identifies and screens diverse microbial strains. AgBiome collaborates with prominent agricultural partners to accelerate discovery processes and broaden the reach of its sustainable products in global markets. With a dedicated team of over 85 employees and a state-of-the-art laboratory and greenhouse facility, AgBiome is committed to improving food production responsibly.

WuXi NextCODE operates as a clinical diagnostics company specializing in sequence-based genomics. The firm provides a platform that assists physicians in obtaining critical clinical insights, enabling rapid and accurate diagnoses for patients. Its services include genome interpretation, data analysis, and data mining, along with security and data protection measures. The company also offers custom integration services and both clinical-grade and non-clinical-grade sequencing. With technology developed over 16 years at deCODE genetics, WuXi NextCODE aims to facilitate the integration of genomic data into patient care and diagnosis. Based in Cambridge, Massachusetts, the company was acquired by WuXi AppTec in 2015 and has since focused on addressing the challenges of genome interpretation and big data in healthcare.

Genuity Science is a company that specializes in clinco-omics data analysis solutions for researchers in the fields of central nervous system, cardiometabolic, and inflammatory diseases. The company provides a comprehensive global genomics platform that facilitates the study of biological data insights, offering services that include study design, genomic sequencing, data storage, interpretation, secondary analysis, and scalable analytics. By leveraging the human genome, Genuity Science aims to empower organizations to enhance patient health through advanced genomic insights and analysis.

Boreal Genomics Inc. is a biotechnology company that specializes in the development and marketing of technologies for the blood-based detection and monitoring of circulating tumor DNA. Founded in 2007 and headquartered in Los Altos, California, with an additional office in Vancouver, Canada, the company focuses on improving cancer patient care through innovative diagnostic tools and research applications. Its OnTarget platform enables highly sensitive detection and quantification of tumor mutations in plasma, facilitating accurate tumor profiling and real-time monitoring of tumor evolution. Boreal Genomics also offers the Aurora tool, which purifies and concentrates nucleic acids from various sample types, enhancing the accuracy of sequencing in liquid biopsy applications. These technologies aim to guide therapy selection, improve the efficiency of clinical trials, and accelerate drug development processes.

AgBiome, LLC is a biotechnology company based in Durham, North Carolina, that focuses on the agriculture industry through the development of biological products. Founded in 2012, AgBiome leverages its expertise in plant-associated microbes and modern genomics to create innovative solutions aimed at enhancing plant health, pest resistance, and crop yields. The company addresses critical agricultural challenges, including soil-borne diseases, insects, and nematodes, by offering fungicides and a platform that identifies and screens diverse microbial strains. AgBiome collaborates with prominent agricultural partners to accelerate discovery processes and broaden the reach of its sustainable products in global markets. With a dedicated team of over 85 employees and a state-of-the-art laboratory and greenhouse facility, AgBiome is committed to improving food production responsibly.

Theraclone Sciences, Inc. is a discovery-stage biotechnology company based in Seattle, Washington, focused on developing novel therapeutic antibodies for cancer and infectious diseases. The company employs its proprietary In-Situ Therapeutic Antibody Rescue technology to rapidly identify and test human antibodies with exceptional biological functions. Theraclone's pipeline includes TCN-032, a recombinant human monoclonal antibody aimed at treating patients hospitalized with severe influenza, along with several preclinical and clinical programs targeting unmet medical needs such as triple-negative breast cancer, infectious disease-associated cancers, and multidrug-resistant bacteria. Founded in 2004 and originally known as Spaltudaq Corporation until its rebranding in 2009, Theraclone leverages the natural immune responses of human subjects to discover rare monoclonal antibodies that could lead to effective therapeutic interventions.

Theraclone Sciences, Inc. is a discovery-stage biotechnology company based in Seattle, Washington, focused on developing novel therapeutic antibodies for cancer and infectious diseases. The company employs its proprietary In-Situ Therapeutic Antibody Rescue technology to rapidly identify and test human antibodies with exceptional biological functions. Theraclone's pipeline includes TCN-032, a recombinant human monoclonal antibody aimed at treating patients hospitalized with severe influenza, along with several preclinical and clinical programs targeting unmet medical needs such as triple-negative breast cancer, infectious disease-associated cancers, and multidrug-resistant bacteria. Founded in 2004 and originally known as Spaltudaq Corporation until its rebranding in 2009, Theraclone leverages the natural immune responses of human subjects to discover rare monoclonal antibodies that could lead to effective therapeutic interventions.

Theraclone Sciences, Inc. is a discovery-stage biotechnology company based in Seattle, Washington, focused on developing novel therapeutic antibodies for cancer and infectious diseases. The company employs its proprietary In-Situ Therapeutic Antibody Rescue technology to rapidly identify and test human antibodies with exceptional biological functions. Theraclone's pipeline includes TCN-032, a recombinant human monoclonal antibody aimed at treating patients hospitalized with severe influenza, along with several preclinical and clinical programs targeting unmet medical needs such as triple-negative breast cancer, infectious disease-associated cancers, and multidrug-resistant bacteria. Founded in 2004 and originally known as Spaltudaq Corporation until its rebranding in 2009, Theraclone leverages the natural immune responses of human subjects to discover rare monoclonal antibodies that could lead to effective therapeutic interventions.

Limerick BioPharma focuses on the development of innovative pharmaceutical compounds aimed at enhancing patient care. The company specializes in creating adjunctive therapies that reduce toxic side effects on non-targeted organs and tissues while preserving or improving the efficacy of existing and investigational drugs. In addition to its adjunctive approaches, Limerick BioPharma is also engaged in developing novel monotherapy compounds specifically targeting metabolic diseases, including hypercholesteremia and hyperglycemia. The company employs advanced methods to simulate blood-tissue barrier activities both in vitro and in vivo, positioning itself as a leader in addressing challenges related to tissue-specific toxicity and solid organ transplantation.

Surface Logix is a drug development company specializing in the creation of innovative small molecule drugs aimed at treating metabolic and cardiovascular diseases. Utilizing its expertise in biophysical chemistry, the company develops new chemical entities that demonstrate significantly enhanced pharmacokinetic and pharmacodynamic properties compared to existing market leaders. Surface Logix focuses on targeting specific tissues and organ systems, including the gastrointestinal and cardiovascular systems, and has various ongoing programs addressing a range of metabolic and cardiovascular conditions.

Limerick BioPharma focuses on the development of innovative pharmaceutical compounds aimed at enhancing patient care. The company specializes in creating adjunctive therapies that reduce toxic side effects on non-targeted organs and tissues while preserving or improving the efficacy of existing and investigational drugs. In addition to its adjunctive approaches, Limerick BioPharma is also engaged in developing novel monotherapy compounds specifically targeting metabolic diseases, including hypercholesteremia and hyperglycemia. The company employs advanced methods to simulate blood-tissue barrier activities both in vitro and in vivo, positioning itself as a leader in addressing challenges related to tissue-specific toxicity and solid organ transplantation.

Limerick BioPharma focuses on the development of innovative pharmaceutical compounds aimed at enhancing patient care. The company specializes in creating adjunctive therapies that reduce toxic side effects on non-targeted organs and tissues while preserving or improving the efficacy of existing and investigational drugs. In addition to its adjunctive approaches, Limerick BioPharma is also engaged in developing novel monotherapy compounds specifically targeting metabolic diseases, including hypercholesteremia and hyperglycemia. The company employs advanced methods to simulate blood-tissue barrier activities both in vitro and in vivo, positioning itself as a leader in addressing challenges related to tissue-specific toxicity and solid organ transplantation.

Surface Logix is a drug development company specializing in the creation of innovative small molecule drugs aimed at treating metabolic and cardiovascular diseases. Utilizing its expertise in biophysical chemistry, the company develops new chemical entities that demonstrate significantly enhanced pharmacokinetic and pharmacodynamic properties compared to existing market leaders. Surface Logix focuses on targeting specific tissues and organ systems, including the gastrointestinal and cardiovascular systems, and has various ongoing programs addressing a range of metabolic and cardiovascular conditions.

Theraclone Sciences, Inc. is a discovery-stage biotechnology company based in Seattle, Washington, focused on developing novel therapeutic antibodies for cancer and infectious diseases. The company employs its proprietary In-Situ Therapeutic Antibody Rescue technology to rapidly identify and test human antibodies with exceptional biological functions. Theraclone's pipeline includes TCN-032, a recombinant human monoclonal antibody aimed at treating patients hospitalized with severe influenza, along with several preclinical and clinical programs targeting unmet medical needs such as triple-negative breast cancer, infectious disease-associated cancers, and multidrug-resistant bacteria. Founded in 2004 and originally known as Spaltudaq Corporation until its rebranding in 2009, Theraclone leverages the natural immune responses of human subjects to discover rare monoclonal antibodies that could lead to effective therapeutic interventions.

VBI Vaccines Inc. is a biopharmaceutical company based in Cambridge, Massachusetts, with research facilities in Ottawa, Canada. It develops and sells vaccines for infectious diseases and immuno-oncology, with a focus on expanding protection in large, underserved markets. The company's enveloped virus-like particle (eVLP) platform enables the creation of vaccines that closely mimic target viruses, eliciting potent immune responses. VBI's commercial product, Sci-B-Vac, is a hepatitis B vaccine approved in Israel and 14 other countries, offering rapid onset of protection and high antibody levels. The company is also developing VBI-2601 for a functional cure of chronic hepatitis B, VBI-1901 for glioblastoma, and VBI-1501 for cytomegalovirus, among other candidates. VBI collaborates with pharmaceutical companies and research institutions, and its products are primarily distributed through direct sales to physicians and pharmacists.

Theraclone Sciences, Inc. is a discovery-stage biotechnology company based in Seattle, Washington, focused on developing novel therapeutic antibodies for cancer and infectious diseases. The company employs its proprietary In-Situ Therapeutic Antibody Rescue technology to rapidly identify and test human antibodies with exceptional biological functions. Theraclone's pipeline includes TCN-032, a recombinant human monoclonal antibody aimed at treating patients hospitalized with severe influenza, along with several preclinical and clinical programs targeting unmet medical needs such as triple-negative breast cancer, infectious disease-associated cancers, and multidrug-resistant bacteria. Founded in 2004 and originally known as Spaltudaq Corporation until its rebranding in 2009, Theraclone leverages the natural immune responses of human subjects to discover rare monoclonal antibodies that could lead to effective therapeutic interventions.

Surface Logix is a drug development company specializing in the creation of innovative small molecule drugs aimed at treating metabolic and cardiovascular diseases. Utilizing its expertise in biophysical chemistry, the company develops new chemical entities that demonstrate significantly enhanced pharmacokinetic and pharmacodynamic properties compared to existing market leaders. Surface Logix focuses on targeting specific tissues and organ systems, including the gastrointestinal and cardiovascular systems, and has various ongoing programs addressing a range of metabolic and cardiovascular conditions.

Integrated Diagnostics Inc. is a company focused on developing laboratory-based blood diagnostic tools that facilitate the early diagnosis of complex diseases through non-invasive blood tests. Established in 2005 and headquartered in Seattle, Washington, the company specializes in products that monitor multiple molecular markers simultaneously, offering valuable insights for conditions such as lung cancer. One of its key offerings is Xpresys Lung, a molecular blood test designed to provide objective information for assessing pulmonary nodules. Integrated Diagnostics is committed to leveraging advanced technologies to create a pipeline of innovative diagnostic products aimed at enhancing disease management for conditions including cancer, diabetes, and Alzheimer's. The company operates under a strategic partnership with Agilent Technologies Inc. and has been functioning as a subsidiary of Biodesix, Inc. since 2018.

Surface Logix is a drug development company specializing in the creation of innovative small molecule drugs aimed at treating metabolic and cardiovascular diseases. Utilizing its expertise in biophysical chemistry, the company develops new chemical entities that demonstrate significantly enhanced pharmacokinetic and pharmacodynamic properties compared to existing market leaders. Surface Logix focuses on targeting specific tissues and organ systems, including the gastrointestinal and cardiovascular systems, and has various ongoing programs addressing a range of metabolic and cardiovascular conditions.

NexCura is a provider of online decision support services aimed at enhancing communication between patients and physicians. The company's applications and custom services are offered through an application service provider model, enabling the collection of comprehensive clinical data. NexCura's tools include the NexProfiler, which integrates clinical evidence with personal concerns and individual patient circumstances to assist in pre-treatment decision-making. Additionally, the company offers patient education and market research services, delivering valuable insights to healthcare organizations, pharmaceutical companies, physicians, and patients alike.

R2 Technology develops and commercializes computer-aided detection systems for the early-detection of breast cancer. R2 Technology pioneered the use of CAD for mammography in 1998 when the ImageChecker system became the first CAD system approved by the FDA for screening mammography. The company was founded in 1993 and is headquartered in Santa Clara, California. As of July 13, 2006, R2 Technology, Inc. operates as a subsidiary of Hologic Inc.

NexCura is a provider of online decision support services aimed at enhancing communication between patients and physicians. The company's applications and custom services are offered through an application service provider model, enabling the collection of comprehensive clinical data. NexCura's tools include the NexProfiler, which integrates clinical evidence with personal concerns and individual patient circumstances to assist in pre-treatment decision-making. Additionally, the company offers patient education and market research services, delivering valuable insights to healthcare organizations, pharmaceutical companies, physicians, and patients alike.

Eichrom Technologies, Inc., established in 1990 and headquartered in Lisle, Illinois, specializes in developing and commercializing chemical separation technologies. The company focuses on radiochemistry, geochemistry, hazardous metals analysis, and environmental screening for dioxins. Eichrom supplies purified cation and anion exchange resins for analytical applications, offers the Procept rapid dioxin assay for sample screening, and provides Diphonix resin for metal removal and purification. Additionally, Eichrom manufactures radiation shielding products, serving clients in the nuclear navy, Department of Energy, and nuclear power generation sectors. The company aims to enhance safety and efficiency in these industries through its engineering and radiation protection expertise.

Nanophase Technologies Corporation, founded in 1989 and headquartered in Romeoville, Illinois, specializes in the production of engineered nanomaterials for diverse industrial applications. The company focuses on developing nano-engineered solutions, offering surface-engineered zinc oxide and titanium dioxide for sunscreens and personal care products. It also provides fully formulated cosmetics under the Solésence brand. Additionally, Nanophase produces advanced materials, including architectural and industrial coatings, abrasion-resistant additives, plastics additives, and products for medical diagnostics. Its technologies aim to deliver tailored nanomaterial solutions across various markets, including personal care, energy, and surface finishing applications. Through its integrated approach, Nanophase Technologies plays a significant role in enhancing product performance across multiple sectors.