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Triveni Bio is a biotechnology company specializing in the development of novel antibody therapies for immunological and inflammatory disorders. The company employs a genetics-driven precision medicine approach to identify patients most likely to respond to its treatments, aiming to accelerate drug development and improve the effectiveness and safety of therapies.

GondolaBio is a biopharmaceutical company dedicated to researching, developing, and manufacturing pharmaceutical products. Its primary focus is on creating therapeutics for patients with genetic diseases, addressing high unmet medical needs across various therapeutic areas and stages of development. The company leverages biological research to drive its mission, aiming to enable the healthcare industry to effectively treat and manage rare genetic conditions.

Sionna Therapeutics was formed in late 2019, leveraging 10 years of large pharma scientific investment and expertise. Our experienced scientific team has been on a mission to fully normalize CFTR function. In the three decades since the discovery of the genetic defects that cause cystic fibrosis (CF), researchers have made remarkable advances for patients. Yet the ultimate goal of CF drug development – to fully normalize the function of CFTR, the key protein leading to the pathology of CF – has remained out of reach.

Triveni Bio is a biotechnology company specializing in the development of novel antibody therapies for immunological and inflammatory disorders. The company employs a genetics-driven precision medicine approach to identify patients most likely to respond to its treatments, aiming to accelerate drug development and improve the effectiveness and safety of therapies.

Pragma Bio is a biotechnology company that uses microbiome-based approaches to discover therapies for cancer and autoimmune diseases, combining genomic sequencing, artificial intelligence, and synthetic biology to identify biomarkers and develop therapeutics through a data-driven platform that aggregates public and private data to build a microbiome database and reveal connections across microbial and clinical data. The company pursues small-molecule discovery from human-associated bacteria, focusing on the gut-immune axis, and aims to deliver health-indicative molecules with robust safety profiles, while the platform supports risk stratification and outcome prediction for patients by leveraging real-world data. Pragma Bio was founded in 2018 in Millbrae, California by Peter McCaffrey, Kovi Bessoff, Ayin Vala and Kareem Barghouti.

Ensoma is a biotechnology company focused on advancing genomic medicine through its innovative in vivo approach, utilizing proprietary Engenious vectors. These vectors are engineered to deliver a wide array of gene modification technologies directly to blood and immune cells, including T cells, B cells, and myeloid cells, without the necessity for stem cell collection or prior myeloablative conditioning, which can pose risks to patients. This unique method allows for the administration of therapies via a single injection, enhancing accessibility and convenience in various healthcare settings, even where resources may be limited. Ensoma aims to expand the curative potential of genomic medicine, making it more accessible to patients in need.

Locus Biosciences is a biotechnology company focused on developing a CRISPR-engineered precision antibacterial platform aimed at transforming the treatment of bacterial diseases. The company integrates the antibacterial capabilities of CRISPR-Cas3 technology with the effective and safe delivery of bacteriophages, which are viruses that specifically target bacteria. This innovative approach allows for rapid initiation of treatment by physicians, leading to improved medical outcomes for patients. Through its advanced platform, Locus Biosciences seeks to address the challenges posed by pathogenic bacteria in a precise and targeted manner.

Fluidigm Corporation develops and markets innovative technologies and tools for life sciences research globally. The company specializes in integrated fluidic circuits that control fluids at the nanoscale, enabling a range of applications in biological research. Its product offerings include analytical systems such as the Helios CyTOF system, the Hyperion imaging system, and the Biomark HD system, along with various assays and reagents designed for immuno-oncology and genetic analysis. Fluidigm also provides preparatory instruments and single-cell microfluidics, such as the C1 and Polaris systems. The company serves a diverse clientele, including academic institutions, clinical research laboratories, biopharmaceutical, biotechnology, and agricultural biotechnology companies, focusing on non-diagnostic and non-clinical applications. Established in 1999 as Mycometrix Corporation, it adopted the name Fluidigm Corporation in 2001 and is headquartered in South San Francisco, California.

Color is a healthcare technology company that offers a comprehensive platform for population health management, facilitating equitable and accessible healthcare delivery. The company specializes in large-scale health initiatives, providing solutions that include population genomics programs and high-throughput testing services, such as those for COVID-19. By centralizing essential healthcare capabilities, Color enables businesses, schools, and state public health departments to implement effective preventive health programs, regardless of the geographical distribution of their populations. Its innovative approach addresses various healthcare logistics challenges, streamlining processes related to testing, screening, treatment, and referrals, while creating diverse market opportunities and revenue streams for clinical teams.

Founded in 2008, Ginkgo Bioworks designs, engineers, and licenses organisms for various applications. It discovers molecules for flavors, sweeteners, cosmetics, crops, pharmaceuticals, and generates probiotic bacteria for health benefits. The company serves markets such as cultured ingredients, carbon mitigation, probiotics, and natural product discovery.

Algen Biotechnologies, Inc. is a therapeutic discovery company focused on drug development through an innovative platform that decodes functional gene networks. The company leverages advanced technologies, including CRISPR and machine learning, to uncover disease-driving RNA messages. By analyzing complex disease signaling and gene networks, Algen aims to facilitate drug discovery for cancer and other diseases with significant unmet medical needs. Its approach seeks to provide valuable insights for drug companies, enabling them to identify and develop effective treatments.

PepGen Ltd. is a clinical-stage biotechnology company based in Oxford, United Kingdom, focused on advancing the next generation of nucleic acid therapeutics, particularly in the treatment of severe neuromuscular and neurologic diseases. Incorporated in 2018, PepGen has developed its Enhanced Delivery Oligonucleotide (EDO) platform, which is designed to improve the uptake and activity of conjugated oligonucleotide therapeutics. The company's innovative EDO peptides enhance tissue penetration, cellular uptake, and nuclear delivery, demonstrating their ability to transport oligonucleotides effectively into various target tissues, including smooth, skeletal, and cardiac muscle, as well as the central nervous system. PepGen aims to unlock the clinical potential of these transformative therapeutics, with a particular emphasis on the effective delivery of antisense oligonucleotides, and is advancing its novel conjugate therapeutics toward clinical application.

GeneDx specializes in delivering personalized insights from genomic data to improve health outcomes. It combines extensive genetic expertise with advanced data science capabilities.

Motif FoodWorks, Inc. is a bio-organism engineering company based in Boston, Massachusetts, that specializes in developing innovative food ingredients. The company focuses on producing animal-free proteins, including meat alternatives and dairy-free proteins, catering to the growing demand for plant-based food solutions. By utilizing fermentation technology, Motif creates essential proteins and nutrients that enhance both nutrition and flavor in food products. The company collaborates with chefs, health experts, and food innovators to develop new ingredient solutions aimed at transforming the food industry and promoting sustainability. Established in 2018 and originally known as Motif Ingredients, Motif FoodWorks rebranded in 2019 to reflect its commitment to advancing the next generation of healthy and plant-based foods.

Ensoma is a biotechnology company focused on advancing genomic medicine through its innovative in vivo approach, utilizing proprietary Engenious vectors. These vectors are engineered to deliver a wide array of gene modification technologies directly to blood and immune cells, including T cells, B cells, and myeloid cells, without the necessity for stem cell collection or prior myeloablative conditioning, which can pose risks to patients. This unique method allows for the administration of therapies via a single injection, enhancing accessibility and convenience in various healthcare settings, even where resources may be limited. Ensoma aims to expand the curative potential of genomic medicine, making it more accessible to patients in need.

Color is a healthcare technology company that offers a comprehensive platform for population health management, facilitating equitable and accessible healthcare delivery. The company specializes in large-scale health initiatives, providing solutions that include population genomics programs and high-throughput testing services, such as those for COVID-19. By centralizing essential healthcare capabilities, Color enables businesses, schools, and state public health departments to implement effective preventive health programs, regardless of the geographical distribution of their populations. Its innovative approach addresses various healthcare logistics challenges, streamlining processes related to testing, screening, treatment, and referrals, while creating diverse market opportunities and revenue streams for clinical teams.

Boost Biomes, Inc. is a company that specializes in developing microbiome products for food and agriculture applications. Founded in 2016 and based in South San Francisco, California, the company utilizes a discovery platform that employs high-throughput sequencing, selective enrichment, and advanced informatics to identify multi-microbial products. This innovative approach is designed to create sustainable solutions for improving food production and extending shelf life while effectively managing diseases in high-value crops. By focusing on naturally occurring microbes, Boost Biomes aims to address challenges related to food security and enhance agricultural practices. The company's efforts represent a significant advancement over traditional methods, offering a faster and more cost-effective means of microbial product development.

Pragma Bio is a biotechnology company that uses microbiome-based approaches to discover therapies for cancer and autoimmune diseases, combining genomic sequencing, artificial intelligence, and synthetic biology to identify biomarkers and develop therapeutics through a data-driven platform that aggregates public and private data to build a microbiome database and reveal connections across microbial and clinical data. The company pursues small-molecule discovery from human-associated bacteria, focusing on the gut-immune axis, and aims to deliver health-indicative molecules with robust safety profiles, while the platform supports risk stratification and outcome prediction for patients by leveraging real-world data. Pragma Bio was founded in 2018 in Millbrae, California by Peter McCaffrey, Kovi Bessoff, Ayin Vala and Kareem Barghouti.

Boost Biomes, Inc. is a company that specializes in developing microbiome products for food and agriculture applications. Founded in 2016 and based in South San Francisco, California, the company utilizes a discovery platform that employs high-throughput sequencing, selective enrichment, and advanced informatics to identify multi-microbial products. This innovative approach is designed to create sustainable solutions for improving food production and extending shelf life while effectively managing diseases in high-value crops. By focusing on naturally occurring microbes, Boost Biomes aims to address challenges related to food security and enhance agricultural practices. The company's efforts represent a significant advancement over traditional methods, offering a faster and more cost-effective means of microbial product development.

4D Molecular Therapeutics, Inc. is a clinical-stage gene therapy company based in Emeryville, California, focused on developing innovative gene therapies for unmet medical needs. The company utilizes targeted and evolved adeno-associated virus (AAV) vectors to create its product candidates, which are concentrated in the therapeutic areas of ophthalmology, cardiology, and pulmonology. Key candidates in its portfolio include 4D-125, currently in a Phase I/II trial for X-linked retinitis pigmentosa, and 4D-110, undergoing Phase I trials for choroideremia. Additionally, 4D-310 is in Phase I/II trials for Fabry disease, while investigational drugs 4D-150 and 4D-710 are being developed for wet age-related macular degeneration and cystic fibrosis lung disease, respectively. Founded in 2013, 4D Molecular Therapeutics aims to advance its gene therapies to address significant health challenges.

Founded in 2008, Ginkgo Bioworks designs, engineers, and licenses organisms for various applications. It discovers molecules for flavors, sweeteners, cosmetics, crops, pharmaceuticals, and generates probiotic bacteria for health benefits. The company serves markets such as cultured ingredients, carbon mitigation, probiotics, and natural product discovery.

Polaris Genomics is focused on advancing mental health diagnostics and therapeutics through the identification of genomic biomarkers. The company has developed the ADAPT Platform™, which integrates a targeted neuropsychiatric gene panel featuring over 1,000 transcriptomic biomarkers relevant to various neuropsychiatric conditions, including anxiety, depression, and PTSD. This platform employs advanced analytics powered by artificial intelligence and machine learning, alongside an expanding data repository. Notably, Polaris Genomics has created the PTS-ID™, the first clinical blood test for PTSD screening, which exemplifies its commitment to providing objective assessment tools for mental health. By mapping biological pathways associated with mental health disorders, Polaris Genomics aims to facilitate more accurate diagnoses and improve therapeutic outcomes, ultimately reducing stigma and promoting mental well-being.

Color is a healthcare technology company that offers a comprehensive platform for population health management, facilitating equitable and accessible healthcare delivery. The company specializes in large-scale health initiatives, providing solutions that include population genomics programs and high-throughput testing services, such as those for COVID-19. By centralizing essential healthcare capabilities, Color enables businesses, schools, and state public health departments to implement effective preventive health programs, regardless of the geographical distribution of their populations. Its innovative approach addresses various healthcare logistics challenges, streamlining processes related to testing, screening, treatment, and referrals, while creating diverse market opportunities and revenue streams for clinical teams.

Algen Biotechnologies, Inc. is a therapeutic discovery company focused on drug development through an innovative platform that decodes functional gene networks. The company leverages advanced technologies, including CRISPR and machine learning, to uncover disease-driving RNA messages. By analyzing complex disease signaling and gene networks, Algen aims to facilitate drug discovery for cancer and other diseases with significant unmet medical needs. Its approach seeks to provide valuable insights for drug companies, enabling them to identify and develop effective treatments.

Founded in 2008, Ginkgo Bioworks designs, engineers, and licenses organisms for various applications. It discovers molecules for flavors, sweeteners, cosmetics, crops, pharmaceuticals, and generates probiotic bacteria for health benefits. The company serves markets such as cultured ingredients, carbon mitigation, probiotics, and natural product discovery.

Motif FoodWorks, Inc. is a bio-organism engineering company based in Boston, Massachusetts, that specializes in developing innovative food ingredients. The company focuses on producing animal-free proteins, including meat alternatives and dairy-free proteins, catering to the growing demand for plant-based food solutions. By utilizing fermentation technology, Motif creates essential proteins and nutrients that enhance both nutrition and flavor in food products. The company collaborates with chefs, health experts, and food innovators to develop new ingredient solutions aimed at transforming the food industry and promoting sustainability. Established in 2018 and originally known as Motif Ingredients, Motif FoodWorks rebranded in 2019 to reflect its commitment to advancing the next generation of healthy and plant-based foods.

Mediphage Bioceuticals specializes in developing safe and effective transgene delivery platforms for gene therapy, cell engineering, and gene editing. Its flagship technology, ministring DNA (msDNA), is a non-viral vector that offers enhanced safety and cost-effectiveness compared to competing solutions.

BridgeBio is a biotechnology company that focuses on genetic disease therapies and develops those assets with the right approach in supporting R&D. BridgeBio creates a bridge from advancements in genetic science to patients with unmet needs via the entrepreneurial engine required to make life-changing medicines as rapidly as possible. BridgeBio's mission is to discover, create, test, and deliver transformative medicines to treat patients with genetic diseases.

4D Molecular Therapeutics, Inc. is a clinical-stage gene therapy company based in Emeryville, California, focused on developing innovative gene therapies for unmet medical needs. The company utilizes targeted and evolved adeno-associated virus (AAV) vectors to create its product candidates, which are concentrated in the therapeutic areas of ophthalmology, cardiology, and pulmonology. Key candidates in its portfolio include 4D-125, currently in a Phase I/II trial for X-linked retinitis pigmentosa, and 4D-110, undergoing Phase I trials for choroideremia. Additionally, 4D-310 is in Phase I/II trials for Fabry disease, while investigational drugs 4D-150 and 4D-710 are being developed for wet age-related macular degeneration and cystic fibrosis lung disease, respectively. Founded in 2013, 4D Molecular Therapeutics aims to advance its gene therapies to address significant health challenges.

Boost Biomes, Inc. is a company that specializes in developing microbiome products for food and agriculture applications. Founded in 2016 and based in South San Francisco, California, the company utilizes a discovery platform that employs high-throughput sequencing, selective enrichment, and advanced informatics to identify multi-microbial products. This innovative approach is designed to create sustainable solutions for improving food production and extending shelf life while effectively managing diseases in high-value crops. By focusing on naturally occurring microbes, Boost Biomes aims to address challenges related to food security and enhance agricultural practices. The company's efforts represent a significant advancement over traditional methods, offering a faster and more cost-effective means of microbial product development.

Founded in 2008, Ginkgo Bioworks designs, engineers, and licenses organisms for various applications. It discovers molecules for flavors, sweeteners, cosmetics, crops, pharmaceuticals, and generates probiotic bacteria for health benefits. The company serves markets such as cultured ingredients, carbon mitigation, probiotics, and natural product discovery.

BridgeBio is a biotechnology company that focuses on genetic disease therapies and develops those assets with the right approach in supporting R&D. BridgeBio creates a bridge from advancements in genetic science to patients with unmet needs via the entrepreneurial engine required to make life-changing medicines as rapidly as possible. BridgeBio's mission is to discover, create, test, and deliver transformative medicines to treat patients with genetic diseases.

Trace Genomics specializes in soil health and microbiome analysis, employing DNA sequencing and artificial intelligence to provide a soil microbiome test that enables early prediction of soil diseases, soil health, and crop quality. The company analyzes microbial composition and quantifies microbes, indexing this data and comparing it with soil chemistry to generate actionable insights for agronomists and corporate partners. Its platform integrates biology and chemistry data to help farmers optimize input use, improve yields, and manage risk, treating soil as a valuable asset. By mapping the soil microbiome, Trace Genomics aims to support sustainable agriculture through informed management decisions.

Founded in 2008, Ginkgo Bioworks designs, engineers, and licenses organisms for various applications. It discovers molecules for flavors, sweeteners, cosmetics, crops, pharmaceuticals, and generates probiotic bacteria for health benefits. The company serves markets such as cultured ingredients, carbon mitigation, probiotics, and natural product discovery.

Vitagene, Inc. is a health technology company that utilizes genomic science and advanced technology to deliver personalized healthcare solutions. Founded in 2014 and based in San Francisco, the company offers a DNA-based personalization platform that helps physicians provide data-driven care. Vitagene's algorithm generates tailored supplement regimens and analyzes extensive patient data, including genetics, blood work, and lifestyle factors, to create customized nutritional plans. Additionally, the company produces DNA health test kits and at-home COVID-19 saliva test kits. It also provides comprehensive health and ancestry reports that encompass diet, exercise, and supplementation insights, ensuring that individuals receive recommendations that align with their specific health needs and goals.

EpiBiome, Inc. is a precision microbiome engineering company based in South San Francisco, California, founded in 2013. The company is dedicated to developing therapies that address infectious diseases in humans and agriculture without relying on small-molecule antibiotics. EpiBiome focuses on phage therapy, which targets specific strains within the microbiome, effectively treating antibiotic-resistant infections. Its applications include treatment for mastitis in dairy cows and addressing infections caused by Escherichia coli in humans. By utilizing advanced sequencing and bioinformatic processes, EpiBiome aims to identify pathogenic bacteria and microbiome changes that contribute to disease, offering innovative alternatives to combat the rising threat of antibiotic resistance. As of July 2018, it operates as a subsidiary of Locus Biosciences, Inc.

Editas Medicine is a clinical-stage biotechnology company based in Cambridge, Massachusetts, with an additional site in Boulder, Colorado. Founded in 2013, the company focuses on the discovery and development of genome editing therapeutics, primarily utilizing its proprietary CRISPR/Cas9 technology. This innovative platform enables precise molecular modifications at the genetic level, with the aim of treating a wide array of serious diseases by addressing their underlying causes. Editas Medicine has established a strong intellectual property portfolio, which includes numerous patents related to foundational genome editing technologies and advancements that facilitate the translation of research into viable human therapeutics. The company's mission is to pioneer transformative genomic medicines that can significantly improve patient outcomes across various genetic disorders.

Founded in 2008, Ginkgo Bioworks designs, engineers, and licenses organisms for various applications. It discovers molecules for flavors, sweeteners, cosmetics, crops, pharmaceuticals, and generates probiotic bacteria for health benefits. The company serves markets such as cultured ingredients, carbon mitigation, probiotics, and natural product discovery.