645 Ventures
645 Ventures is an early‑stage venture capital firm based in New York that partners with founders to build iconic companies. It makes seed and Series A investments across software and technology‑enabled sectors, including enterprise SaaS, infrastructure software, fintech, online marketplaces, consumer technology, and augmented or virtual reality. The firm emphasizes themes such as SaaS for the second wave, citizen professionals, the engineering value chain revolution, and personalized consumer applications, and supports portfolio companies through its connected network and Voyager platform to help them scale to growth. It manages more than $200 million in assets and operates across North America, backing a diverse set of companies that mature into growth stages and, in some cases, reach acquisitions by larger tech players.
Top Stages
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Past deals in Simulation
True Anomaly
Series C in 2025
True Anomaly develops space security and resilience solutions by integrating autonomous spacecraft operations, artificial intelligence, and mission-specific software. The company designs, builds, and fields technologies that enable secure and sustainable access to orbital environments for defense agencies, allied governments, and commercial operators. Its offerings improve orbital situational awareness, maintain operational continuity, and support long-term space sustainability across critical infrastructure and strategic missions.
True Anomaly
Series B in 2023
True Anomaly develops space security and resilience solutions by integrating autonomous spacecraft operations, artificial intelligence, and mission-specific software. The company designs, builds, and fields technologies that enable secure and sustainable access to orbital environments for defense agencies, allied governments, and commercial operators. Its offerings improve orbital situational awareness, maintain operational continuity, and support long-term space sustainability across critical infrastructure and strategic missions.
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