25Madison, LLC is a venture platform founded in 2018 and headquartered in New York, with additional offices in Miami, Atlanta, and Tel Aviv. The firm specializes in incubation and early-stage investments, focusing on building companies from the ground up. Its operations are divided into four key segments: the General Studio, which develops companies across various sectors; 25M Health, dedicated to health technology startups in collaboration with LifePoint Health; the Ventures Fund, which invests in pre-seed to Series A startups with an emphasis on B2B SaaS, fintech, and healthtech; and 25M Create, a brand and experience agency that offers services like brand strategy, visual identity, experience design, and digital marketing. Through these initiatives, 25Madison aims to support entrepreneurs at all stages of their business journey.
Ranger AI helps manufacturers decrease response time to win new business, increase bid throughput.
Keragon
Seed Round in 2025
Keragon operates a HIPAA-compliant workflow automation platform designed to streamline and automate healthcare processes. The company provides healthcare organizations with the tools to integrate various systems, facilitating the automation of routine tasks such as appointment scheduling, electronic health records management, patient intake, and billing. By simplifying these workflows, Keragon enables healthcare teams to enhance operational efficiency, lower costs, and ultimately improve the quality of patient care.
Paxton
Series A in 2025
Paxton is a legal tech company that utilizes cutting-edge AI technology to transform the way legal professionals work. Our robust AI platform ingests vast sources of legal information, including all state and federal laws and regulations, and provides precise, relevant, and insightful responses to user queries. From answering questions about regulations to drafting legal documents, Paxton AI transforms the legal research and analysis process, saving time and increasing efficiency.
Wilya
Seed Round in 2024
Wilya is a developer of workforce management software focused on transforming the future of work in industrial manufacturing and logistics. By leveraging its expertise in manufacturing and human resources, the company addresses the challenges of managing a flexible workforce. Wilya's innovative SaaS platform aims to enhance work culture in factories by promoting diversity, minimizing mandatory overtime, and operationalizing flexibility. This approach seeks to dismantle traditional rigid work schedules, allowing factories to tap into diverse talent pools and create a more dynamic and engaged workforce.
Quantivly
Seed Round in 2023
Quantivly, Inc. is a technology company based in Somerville, Massachusetts, that specializes in artificial intelligence solutions for radiology. Founded in 2019, it focuses on developing software that manages and analyzes MRI imaging workflows. The company's platform enables radiology providers to access a vendor-neutral, granular source of operational data by analyzing and harmonizing scanner information. This capability supports radiology departments and imaging centers in making data-driven decisions, improving operational efficiency, and enhancing patient-centered healthcare. By offering tools for data liquidity and analysis, Quantivly aims to increase access to medical imaging and drive advancements in research and patient care within the radiology sector.
Midi Health
Series A in 2023
Midi Health is a virtual care clinic dedicated to addressing the health needs of women, particularly during menopause and related conditions. The clinic specializes in treating issues such as depression, gynecological cancer, and menstrual problems through a clinical platform that delivers personalized care protocols. These protocols are administered by clinicians who are trained in female midlife health. Midi Health enhances its services by utilizing specialized at-home labs, providing prescription medications, supplements, and lifestyle coaching. This comprehensive approach aims to empower women to manage the challenges they face during critical stages of their lives and careers.
Paxton
Seed Round in 2023
Paxton is a legal tech company that utilizes cutting-edge AI technology to transform the way legal professionals work. Our robust AI platform ingests vast sources of legal information, including all state and federal laws and regulations, and provides precise, relevant, and insightful responses to user queries. From answering questions about regulations to drafting legal documents, Paxton AI transforms the legal research and analysis process, saving time and increasing efficiency.
Croissant
Seed Round in 2023
Croissant provides Guaranteed Buybacks at Point of Sale and beyond, enabling retailers and consumers to benefit from the resale ecosystem.
Thrive Health Tech
Pre Seed Round in 2023
Thrive Health Tech is a healthcare-focused mobile company.
Novacy
Pre Seed Round in 2023
Novacy specializes in conversational intelligence by offering a behavioral intelligence platform that enhances customer relationship management, sales, marketing, and customer service. The company’s technology analyzes audio, text, and body language during interactions, allowing clients to gain a deeper understanding of each conversation without manual review. This analysis helps identify the strengths and weaknesses of sales representatives, offering actionable insights that can be used for coaching and improving sales effectiveness. By leveraging these behavioral insights from virtual sales meetings, Novacy empowers businesses to streamline their sales processes and increase their closing rates.
Pattern
Seed Round in 2023
Pattern is a financial membership service that offers users access to a personal financial advisory team supported by a robo-advisory platform. The company specializes in developing financial software that assists customers in managing their finances through comprehensive financial plans and asset management services. Pattern's offerings include access to private equity and other financial services, focusing on maximizing the value of assets while managing risk. This approach enables users to earn higher returns than traditional methods, helping them achieve their financial goals and grow their wealth more effectively.
Swap Health
Seed Round in 2022
Swap Health is a telehealth platform that focuses on making clinical nutrition accessible to individuals, particularly those with chronic conditions or those aiming to prevent such issues. The platform connects users with registered dietitians and health coaches who possess diverse expertise in various dietary needs. By doing so, it provides personalized nutrition guidance tailored to the unique requirements of each individual. Additionally, Swap Health offers cash back on healthy groceries, assisting low-to-moderate-income households in obtaining nutritious food options at a more affordable price. This approach enhances access to essential dietary support while promoting overall health and well-being.
VineSight
Seed Round in 2022
VineSight uses content-agnostic AI to identify suspicious share patterns whether it’s spread by tweets, posts, deepfakes, videos, or memes. With VineSight customized solutions, users can respond quickly to toxic attacks while maintaining control of their brand's story. VineSight's AI-powered technology provides precise, all-encompassing protection across social media platforms and online forums, allowing for rapid mitigation of reputational threats.
Demoleap
Seed Round in 2022
Demoleap is an Israeli-founded company that offers an AI-powered live demo assistant and sales discovery platform designed to enhance the effectiveness of sales teams. With offices in Delaware, Israel, and Ireland, Demoleap provides technology that allows sales representatives to conduct improved demos by shifting focus from merely operating demos to delivering value. Its platform automatically offers insights, tracks and logs demo activities, which helps sales teams increase efficiency and execute more compelling demonstrations. The company is backed by notable US investors and firms, including former Cisco CMO Blair Christie and Aforza CEO Dominic Dinard.
Onda
Series B in 2022
Onda is a spirits brand for a new generation of drinkers. Onda’s first product is a line of canned sparkling tequila beverages, made with blanco tequila and real, legit fruit. Onda’s beverages are all 5% ABV, 100 calories, zero sugar, zero carbs and naturally gluten free. Onda’s brand is inspired by the surf style of the ‘90s.
ModernLTV
Pre Seed Round in 2022
10%+ of annual subscription revenue is lost to unnecessary customer churn. Increased cost of living, zero switching costs, and a lack of predictive insights make it harder than ever to combat churn. Introducing ModernLTV, a no-code retention platform for consumer billers (mobile, cable/tv, insurance) and subscription businesses (streaming, health & wellness, eLearning). Powered by proprietary Retention Intelligence and purpose-built for marketers, Modern delivers real-time predictive insights and automated workflows to combat churn and maximize LTV — all with zero engineering. Launch a FREE test drive in just minutes and get a complimentary Retention Health Check. Start reducing churn today www.modernltv.com/get-started
Handspring
Seed Round in 2022
Handspring is a provider of mental healthcare services focused on children, adolescents, and young adults. The company aims to enhance the family mental healthcare experience by integrating various modalities of care, including in-person sessions, digital platforms, and therapeutic devices. Handspring offers a range of services such as video sessions, skill-based exercises, parent education, medication management, and therapy guidance. By leveraging technology and partnering with health plans, Handspring seeks to make quality mental healthcare more accessible to families, ensuring that children receive timely and personalized therapy tailored to their unique needs. The approach emphasizes empowering young individuals with lifelong tools for growth and well-being.
Eon Health
Series A in 2022
Eon Health is a healthcare technology company based in Denver, Colorado, that specializes in software solutions designed to enhance complex patient management. Founded in 2015 as Matrix Analytics and rebranded in 2018, Eon Health focuses on improving the way healthcare data is gathered, curated, and shared among professionals. Its EonDirect software platform integrates with hospitals' existing electronic health record (EHR) and electronic medical record (EMR) systems, providing an online dashboard that aids healthcare providers in diagnosing and treating complex diseases. The company currently collaborates with 31 hospitals to manage over 12,000 patients, ensuring that critical data is accessible to the right professionals at the right time.
Sagewell Financial
Seed Round in 2022
Sagewell Financial is a company focused on transforming the financial landscape for older adults. It offers a financial platform designed to enhance security for this demographic, enabling users to construct their own retirement paychecks and access free checking services. Additionally, Sagewell Financial provides personalized support through retirement success advocates, who guide clients in making informed financial decisions for retirement. With a team of professionals from technology, insurance, and financial services backgrounds, Sagewell Financial aims to empower older individuals in managing their financial futures effectively.
Intellihealth
Seed Round in 2021
Intellihealth develops medical technology software to diagnose obesity-related diseases. The company's flagship product, Evolve, enables medical providers to offer effective medical obesity treatment to new and existing patients, both via telehealth and in person.
Intellihealth
Seed Round in 2021
Intellihealth develops medical technology software to diagnose obesity-related diseases. The company's flagship product, Evolve, enables medical providers to offer effective medical obesity treatment to new and existing patients, both via telehealth and in person.
Opsera
Series A in 2021
At Opsera, we share a vision for the future of software delivery. Our vision is to empower software and DevOps engineers to deliver software faster, safer and smarter by providing them with a continuous orchestration platform that enables choice of any CI/CD tools and no-code automation across the entire DevOps life cycle. Opsera’s continuous orchestration platform provides self-service toolchain automation, drag-and-drop declarative pipelines, and unified insights. With Opsera, development teams can increase software velocity while using the tools they want, operations teams gain improved efficiency while reducing risk and complexity, and business leaders have unparalleled visibility. Opsera believes that DevOps has transformed from an aspiration to a practical science, and its platform is purpose-built to help organizations accelerate DevOps adoption and reach peak innovation velocity.
Boosted Commerce
Series A in 2021
Boosted Commerce is a consumer packaged goods platform that specializes in acquiring, investing in, and growing third-party seller businesses on e-commerce platforms like Shopify and Amazon. The company focuses on assisting these sellers by offering fair market-driven rates for their brands, allowing them to transition smoothly while Boosted Commerce enhances and expands their businesses. Additionally, the company engages in original product development across various verticals, facilitating significant growth for the brands it partners with. Through its strategic approach, Boosted Commerce aims to accelerate the success of consumer brands in the online marketplace.
Coterie
Seed Round in 2021
Coterie offers a curated selection of elevated party supplies. Customers can find everything they need to throw a memorable party with Coterie's curated collections. Coterie's sells everything from party sets to glitter candles. Customers can find exactly what they want by filtering by occasion, color, or product type.
OROS
Series A in 2021
OROS is a material technology company that specializes in designing and developing advanced insulative outerwear. Utilizing its patented Aerogel-based Solarcore technology, which was originally derived from NASA's insulation for space suits and Mars Rovers, OROS has created a unique solution that allows for thinner, warmer, and more flexible outerwear. By infusing Aerogel into their products, the company enhances thermal performance, making outdoor apparel more efficient and comfortable. Through its innovative approach, OROS is redefining the outerwear market by making advanced thermal solutions accessible to consumers.
Onda
Series A in 2021
Onda is a spirits brand for a new generation of drinkers. Onda’s first product is a line of canned sparkling tequila beverages, made with blanco tequila and real, legit fruit. Onda’s beverages are all 5% ABV, 100 calories, zero sugar, zero carbs and naturally gluten free. Onda’s brand is inspired by the surf style of the ‘90s.
Sourse
Seed Round in 2021
Sourse is a food tech company that aims to set high standards for efficacy and sustainability in the category. They developing new formats for vitamins and supplements. The company's mission is to design clean, delicious functional snacks that serve people and the planet. Their first product is a vitamin-infused chocolate. Sourse was founded by Jenne Moore and Andrew Remlinger.
US Bitcoin
Series A in 2021
US Bitcoin Corporation focuses on building and operating data centers that secure the Bitcoin network. The company emphasizes sustainable operations by utilizing low- and no-carbon energy sources. It provides cost-effective bitcoin mining services, making mining accessible to a wider audience. The corporation aims to enhance the efficiency of its operations while contributing to the overall stability and security of the Bitcoin blockchain.
Truehold
Seed Round in 2021
Truehold offers a sale-leaseback service designed specifically for senior citizens, allowing them to access the full value of their home equity while continuing to live in their residence. This program alleviates the burdens of home maintenance and financial responsibilities by purchasing the home outright and providing a rental arrangement. As a result, seniors can enjoy a comfortable living situation without the stresses associated with homeownership, fostering a healthy and happy lifestyle at home.
Onda
Series A in 2021
Onda is a spirits brand for a new generation of drinkers. Onda’s first product is a line of canned sparkling tequila beverages, made with blanco tequila and real, legit fruit. Onda’s beverages are all 5% ABV, 100 calories, zero sugar, zero carbs and naturally gluten free. Onda’s brand is inspired by the surf style of the ‘90s.
Great American Plant
Seed Round in 2021
Great American Plant offers plant-based protein solutions for user brands, menus, and restaurants. They provide plant-based meatballs, burger patties, and sausage patties. Their solutions reduce greenhouse gas emissions.
Ruby
Pre Seed Round in 2020
Ruby specializes in the health and wellness of seniors and their families with home maintenance and healthcare services for a living. Founded in 2020, Ruby's mission empowers seniors to maintain their independence by living in and loving their homes.
Park & Diamond
Venture Round in 2020
Park & Diamond, Inc. designs and manufactures ultra-portable and collapsible cycling helmets, offering a practical alternative to traditional bulky designs. Founded in 2015, the company is headquartered in Brooklyn, New York. Its innovative helmets feature a compact design with interchangeable skins, making them easy to store and transport. The helmets are equipped with hand-washable layers and provide ultraviolet protection, ensuring that cyclists receive necessary safety while riding bicycles or kick scooters. By focusing on portability and functionality, Park & Diamond aims to enhance the cycling experience for users.
Onda
Seed Round in 2020
Onda is a spirits brand for a new generation of drinkers. Onda’s first product is a line of canned sparkling tequila beverages, made with blanco tequila and real, legit fruit. Onda’s beverages are all 5% ABV, 100 calories, zero sugar, zero carbs and naturally gluten free. Onda’s brand is inspired by the surf style of the ‘90s.
harbor
Pre Seed Round in 2020
harbor's app and readiness platform provides a simple, relatable way to assess and develop preparedness and gain peace-of-mind. By curating expert advice and personalizing, automating, and gamifying key aspects of home safety, harbor aims to make getting ready for the unexpected a fun and easy part of everyday habits.
harbor
Seed Round in 2020
harbor's app and readiness platform provides a simple, relatable way to assess and develop preparedness and gain peace-of-mind. By curating expert advice and personalizing, automating, and gamifying key aspects of home safety, harbor aims to make getting ready for the unexpected a fun and easy part of everyday habits.
Onda
Seed Round in 2020
Onda is a spirits brand for a new generation of drinkers. Onda’s first product is a line of canned sparkling tequila beverages, made with blanco tequila and real, legit fruit. Onda’s beverages are all 5% ABV, 100 calories, zero sugar, zero carbs and naturally gluten free. Onda’s brand is inspired by the surf style of the ‘90s.
Demoleap
Pre Seed Round in 2020
Demoleap is an Israeli-founded company that offers an AI-powered live demo assistant and sales discovery platform designed to enhance the effectiveness of sales teams. With offices in Delaware, Israel, and Ireland, Demoleap provides technology that allows sales representatives to conduct improved demos by shifting focus from merely operating demos to delivering value. Its platform automatically offers insights, tracks and logs demo activities, which helps sales teams increase efficiency and execute more compelling demonstrations. The company is backed by notable US investors and firms, including former Cisco CMO Blair Christie and Aforza CEO Dominic Dinard.
REWIRE
Pre Seed Round in 2020
REWIRE is a cutting-edge health and fitness training system specifically designed to upgrade whole-body performance. REWIRE's proprietary system combines five technologies into a full-stack exercise and recovery program that optimizes sleep, energy, focus, and cognitive and athletic performance.
Tigapo
Seed Round in 2020
Tigapo operates a digital platform that connects coin-operated machines to the cloud for data collection and analysis. Founded in 2016 and based in Tel Aviv, Israel, the company offers a payment solution that allows users to pay for services using smartphones and near-field communication technology. The platform enables the remote control and management of machines, facilitating real-time data analysis and customer profiling. By employing innovative algorithms, Tigapo allows machine owners to autonomously manage their operations, significantly reducing operational costs and enhancing revenue potential.
Onda
Pre Seed Round in 2020
Onda is a spirits brand for a new generation of drinkers. Onda’s first product is a line of canned sparkling tequila beverages, made with blanco tequila and real, legit fruit. Onda’s beverages are all 5% ABV, 100 calories, zero sugar, zero carbs and naturally gluten free. Onda’s brand is inspired by the surf style of the ‘90s.
Forks Over Knives
Seed Round in 2019
Forks Over Knives, LLC is a multimedia brand based in Santa Monica, California, focused on promoting a healthy lifestyle through whole-food, plant-based living. The company provides ready-to-eat plant-based meals and offers an online culinary school, equipping customers with the knowledge and skills necessary for a fulfilling diet. In addition to its meal offerings, Forks Over Knives features a platform that includes a variety of whole-food plant-based recipes, health-related articles, and meal planning tools. By emphasizing the benefits of a plant-based lifestyle, such as increased energy and improved health outcomes, Forks Over Knives aims to empower individuals to make healthier dietary choices.
Park & Diamond
Seed Round in 2019
Park & Diamond, Inc. designs and manufactures ultra-portable and collapsible cycling helmets, offering a practical alternative to traditional bulky designs. Founded in 2015, the company is headquartered in Brooklyn, New York. Its innovative helmets feature a compact design with interchangeable skins, making them easy to store and transport. The helmets are equipped with hand-washable layers and provide ultraviolet protection, ensuring that cyclists receive necessary safety while riding bicycles or kick scooters. By focusing on portability and functionality, Park & Diamond aims to enhance the cycling experience for users.
Verifi Water
Seed Round in 2019
Verifi Water is a water-monitoring platform that delivers real-time water quality intelligence. Their water quality surveillance systems are based on proprietary, advanced material technologies that enable the rapid detection of pathogens, contaminants, and chemicals of concern.
Parmela Creamery
Seed Round in 2019
Parmela Creamery is a New York City-based manufacturer specializing in plant-based cheeses, such as cashew cheese and nut cheese. The company employs traditional cheese-making techniques, including culturing and aging, to create a variety of products that replicate the taste and texture of dairy cheese. Its product lineup includes shreds, slices, sauces, dips, spreads, blocks, and ravioli, all designed to provide superior plant-based nutrition. Parmela Creamery markets its offerings through various food retail stores, making its innovative and authentic cashew-based cheese products accessible to a broad range of consumers.
Steady
Series A in 2019
Steady removes barriers to earn through its income intelligence that supports over 3 million hourly, 1099 and mixed-earners in earning more, an average of over $5,500 per year. Steady's view of income also applies its technology for purposes of income measurement that fills the wage data gap for public and private sector entities that service this worker population in areas such as the administration of public sector benefits. Steady was founded in 2017.
Verifi Water
Seed Round in 2019
Verifi Water is a water-monitoring platform that delivers real-time water quality intelligence. Their water quality surveillance systems are based on proprietary, advanced material technologies that enable the rapid detection of pathogens, contaminants, and chemicals of concern.
Skylark
Seed Round in 2019
Skylark is a travel agency that allows clients to leverage technology when they want it and real people and expert advice when they need it. The company's vision is not just about enabling a better booking experience. More importantly, it's about creating exceptional vacations through better pricing and amenities for hotel and airfare, and a unique combination of unrivaled service, high-tech trip-planning tools and peace of mind. The company was founded in 2015 and based in New York.
Verifi Water
Seed Round in 2019
Verifi Water is a water-monitoring platform that delivers real-time water quality intelligence. Their water quality surveillance systems are based on proprietary, advanced material technologies that enable the rapid detection of pathogens, contaminants, and chemicals of concern.
Mud\Wtr
Pre Seed Round in 2018
MUD\WTR is a producer of organic beverages that provide health and performance benefits through a blend of natural ingredients. The company offers coffee alternatives made from adaptogenic mushrooms such as reishi, lion's mane, and cordyceps, combined with cacao, chia, turmeric, cinnamon, and sea salt. These beverages aim to deliver energy, focus, and immune support without the jitters or crashes associated with traditional coffee. MUD\WTR is committed to promoting healthy minds through the cultivation of healthy habits, positioning itself as a natural alternative to conventional caffeinated drinks.
BOU Brands
Series B in 2018
BOU Brands, LLC, founded in 2016 and headquartered in New York, specializes in the production of bouillon cubes and ready-to-eat soups. The company also offers a diverse range of food products, including risottos, dips, pies, pizzas, and salads. BOU Brands emphasizes the use of real, all-natural ingredients in its offerings, aiming to provide flavorful and convenient meal solutions without compromising health or quality. The company's dedication to creating tastier and healthier food options reflects its commitment to enhancing the dining experience for consumers.
Steady
Series A in 2018
Steady removes barriers to earn through its income intelligence that supports over 3 million hourly, 1099 and mixed-earners in earning more, an average of over $5,500 per year. Steady's view of income also applies its technology for purposes of income measurement that fills the wage data gap for public and private sector entities that service this worker population in areas such as the administration of public sector benefits. Steady was founded in 2017.
Tigapo
Seed Round in 2018
Tigapo operates a digital platform that connects coin-operated machines to the cloud for data collection and analysis. Founded in 2016 and based in Tel Aviv, Israel, the company offers a payment solution that allows users to pay for services using smartphones and near-field communication technology. The platform enables the remote control and management of machines, facilitating real-time data analysis and customer profiling. By employing innovative algorithms, Tigapo allows machine owners to autonomously manage their operations, significantly reducing operational costs and enhancing revenue potential.
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