ARK Investment Management

Hammerspace is a software-defined data orchestration and storage company that provides a unified, cross-platform file access solution through a Parallel Global File System. This system spans diverse storage types, vendors, locations, and clouds, creating a global namespace that enables direct multi-protocol access to all files regardless of storage or geography. A common metadata layer is shared across users and locations, so files are accessed via a single metadata view rather than duplicated copies. When local processing is needed, instantiation of a file is orchestrated in the background and remains transparent to users. The platform virtualizes and abstracts data from underlying infrastructure, delivering file data as a service to applications and data services, supporting hybrid IT environments with minimal disruption to workloads.

Founded in 2012, Coinbase operates a platform enabling merchants and consumers to buy, sell, and store cryptocurrencies like Bitcoin, Ethereum, and Litecoin. It offers products such as Coinbase Wallet, USD Coin, Coinbase Pro, and custody services. The company is headquartered in San Francisco.

Lucra Sports is a social-first sports gaming company that blends fantasy sports concepts with real-world competition. Its B2B technology enables consumer platforms to host cash, cashless, or e-commerce contests and supports staking money in a range of skill-based activities, including sports, yard games, drinking games, board games, and video games. The platform helps brands deliver differentiated, interactive experiences that engage users through social features and competitive gameplay, connecting players, brands, and content to build active communities around diverse forms of play.

Sortium is an entertainment technology startup that merges artificial intelligence with Web3 principles to enhance game content creation. The company has developed a platform for the real-time generation and modification of 3D assets and textures through natural language processing. This innovative approach allows users to efficiently streamline the tokenization process, simulate economic dynamics, and create professional-grade assets for games and virtual productions. By leveraging AI, Sortium enables businesses to produce high-quality content with greater efficiency, transforming the landscape of interactive entertainment.

Relation Therapeutics is a biotechnology company focused on advancing drug discovery and development. It utilizes human genetics and clinical omics data, alongside patient-derived tissue samples, to identify and validate therapeutic programs. The company employs machine learning to explore the relationships between genes, proteins, and drugs, generating insights that have real translational validity. By combining single-cell multi-omics from patient tissues with functional assays, Relation Therapeutics aims to deepen the understanding of biological processes in human health and disease. This approach enables healthcare providers to discover and develop novel treatments, particularly in areas with unmet medical needs.

Shield AI Inc is an artificial intelligence robotics company based in San Diego, California, focused on developing advanced AI-powered systems for national security and first responders. Incorporated in 2015, the company specializes in creating technologies that enhance the safety of military personnel and civilians. Its flagship products include Nova, an autonomous quadcopter drone equipped with lidar technology that operates effectively in GPS-denied environments, and Hivemind, an AI framework that allows various unmanned vehicles to learn from real and synthetic experiences, enabling autonomous operations without direct human control. Additionally, Shield AI has developed the V-BAT, a vertical takeoff and landing aircraft that can navigate contested environments and has been utilized in regions like the Black Sea and the Middle East. The company aims to transform defense operations by leveraging cutting-edge AI and machine learning technologies to execute complex tasks in dynamic and denied environments.

Humata is an AI research assistant that provides answers to questions asked by the user on files such as technical papers and reports. It also allows users to upload files and documents.

Rize ETF is committed to challenging orthodoxy and providing investors with seamless access to the most ground-breaking megatrends shaping the planet.

Palantir Technologies develops data fusion, integration, and analytics software for public institutions, commercial enterprises, and non-profit organizations worldwide. The company offers Gotham, a platform that integrates, manages, secures, and analyzes enterprise data, and Metropolis, a platform that integrates, enriches, models, and analyzes quantitative data for commercial use. Palantir's software supports activities such as anti-fraud, crisis response, cyber security, defense, disaster preparedness, disease response, healthcare delivery, intelligence, law enforcement, insurance analytics, and pharmaceutical research. Its solutions enable collaboration across and within organizations to make sense of large and complex data sets. Palantir serves government, defense, finance, healthcare, and other industries. The company was founded in 2003 and is based in Palo Alto, California.

Archer develops and operates all-electric vertical takeoff and landing aircraft, aiming to enhance urban mobility sustainably. Its four-passenger aircraft can travel up to 60 miles at speeds reaching 150 mph with minimal noise.

Hammerspace is a software-defined data orchestration and storage company that provides a unified, cross-platform file access solution through a Parallel Global File System. This system spans diverse storage types, vendors, locations, and clouds, creating a global namespace that enables direct multi-protocol access to all files regardless of storage or geography. A common metadata layer is shared across users and locations, so files are accessed via a single metadata view rather than duplicated copies. When local processing is needed, instantiation of a file is orchestrated in the background and remains transparent to users. The platform virtualizes and abstracts data from underlying infrastructure, delivering file data as a service to applications and data services, supporting hybrid IT environments with minimal disruption to workloads.

Mythical Games Inc. is a game technology studio founded in 2018 and based in Sherman Oaks, California, with an additional office in Seattle, Washington. The company develops blockchain-based games and aims to create a new generation of gaming experiences by enabling true ownership of digital assets, verifiable scarcity, and integrated secondary markets. Its flagship title, Blankos, is a casual multiplayer game where players can buy, trade, and sell their unique designs. Mythical Games also provides tools for content creators and brands, allowing them to customize and own game assets. By fostering a decentralized gaming ecosystem, the company brings players, developers, and content creators together, promoting personalized experiences and driving consumer adoption of distributed ledger technology through innovative gaming products.

CrowdStrike is a cloud-native cybersecurity company that provides the Falcon platform, a unified security solution for endpoints, cloud workloads, identity and data. The platform combines antivirus, endpoint detection and response, IT hygiene, threat intelligence, and managed threat hunting, along with incident response and ransomware protection. It also offers professional services and training to strengthen cybersecurity capabilities. CrowdStrike serves a wide range of sectors worldwide, including public sector, financial services, healthcare, energy and large enterprises. Founded in 2011 and headquartered in Irvine, California, it maintains a global presence with operations across the United Kingdom, Australia and New Zealand, Asia Pacific and the Middle East. The company positions itself as a leader in cloud-native security, enabling rapid detection and response to threats across an organization's IT ecosystem.

Grayscale is an experienced asset management firm specializing in cryptocurrency investments. Established over a decade ago, it offers a diverse range of crypto investment products, providing exposure to various digital currencies through familiar structures for financial advisors and individual investors.

Founded in 2012, Coinbase operates a platform enabling merchants and consumers to buy, sell, and store cryptocurrencies like Bitcoin, Ethereum, and Litecoin. It offers products such as Coinbase Wallet, USD Coin, Coinbase Pro, and custody services. The company is headquartered in San Francisco.

NVIDIA specializes in the design and manufacture of graphics processing units (GPUs), initially for gaming and professional visualization, but now also widely used in artificial intelligence, data center, and automotive markets. The company's products include GeForce for PC gaming, Quadro for design professionals, Tesla for AI acceleration, DRIVE for autonomous vehicles, and Jetson for embedded systems. NVIDIA serves a broad range of customers, including OEMs, system builders, retailers, cloud service providers, automotive manufacturers, and start-ups.

Leisen performs R&D of industry-leading radar technologies and products for solid protection for the safety of urban low airspace.

Adaptive Biotechnologies Corporation is a commercial-stage company focused on advancing immune-driven medicine by leveraging the biology of the adaptive immune system to enhance disease diagnosis and treatment. Established in 2009 and headquartered in Seattle, Washington, the company offers a range of products and services, including its FDA-authorized clonoSEQ diagnostic test, which is designed for the detection and monitoring of minimal residual disease in patients with specific blood cancers, such as multiple myeloma and chronic lymphocytic leukemia. In addition to clonoSEQ, Adaptive Biotechnologies provides immunoSEQ research services and kits to support scientific research and the discovery of new diagnostic signals. The company also has a pipeline of clinical products aimed at diagnosing and managing various diseases, including cancers, autoimmune disorders, and infectious diseases. It maintains strategic collaborations with notable partners such as Genentech and Microsoft to develop innovative therapies and diagnostic tests.

Burning Rock Biotech is a cancer diagnostics company that leverages next-generation sequencing and bioinformatics to guide personalized cancer treatment. It develops and provides a portfolio of tissue- and blood-based, NGS-driven therapy selection tests, including OncoScreen Plus, LungPlasma, ColonCore and HRDCore, and evaluates biomarkers such as microsatellite instability, tumor mutation burden, and NTRK fusions across multiple cancer types, including lung, gastrointestinal, prostate, breast, hematologic, thyroid, colorectal, ovarian, pancreatic, and bladder cancers. The company supports clinical and research use through one-stop services spanning genetic testing and companion diagnostic development, operating through central laboratory and in-hospital models. It collaborates with major pharmaceutical companies on clinical trials and research to advance targeted therapies and diagnostics. Founded in 2014, it is headquartered in Guangzhou, with a Guangzhou laboratory and an R&D center in Shanghai, reflecting its focus on expanding access to precision oncology in China.

Hyperfine is a pioneering medical device company that developed Swoop®, the world's first FDA-cleared point-of-care MRI system. Designed to enhance patient access to critical care, Swoop produces high-quality images rapidly and at a lower cost than conventional MRIs, enabling clinicians to diagnose and treat patients swiftly in various clinical settings.

Mynaric AG, established in 2009 and headquartered in Gilching, Germany, specializes in laser communication solutions for high-speed, long-distance wireless data transmission between moving objects. The company offers a range of terminals including air-to-ground, air-to-air, space terminals, and optical ground stations, catering to applications in space, air, and ground sectors. Its products facilitate secure, high-data rate connectivity for satellite constellations, airborne networks, and other mobility-based applications.

Nextdoor operates a social networking platform connecting neighbors globally, fostering local conversations and community support. It offers services like Help Map to assist vulnerable residents during crises. The company is headquartered in San Francisco with operations across multiple countries.

Zoom Video Communications, Inc. is a software company that offers a video-first communications platform, enabling users to connect through video, voice, chat, and content sharing. Founded in 2011 and headquartered in San Jose, California, Zoom's product portfolio includes Zoom Meetings, which facilitates HD video and audio conferencing; Zoom Phone, an enterprise cloud phone system; and Zoom Chat for messaging and content exchange. The company also provides Zoom Rooms for conference settings, tools for large-scale webinars, and developer solutions for integrating its services into other applications. Its platform supports collaboration across mobile devices, desktops, and telephones, catering to a diverse range of industries including education, healthcare, finance, and government. With a mission to enhance real-time collaboration, Zoom has established itself as a leader in the communications sector.

Palantir Technologies develops data fusion, integration, and analytics software for public institutions, commercial enterprises, and non-profit organizations worldwide. The company offers Gotham, a platform that integrates, manages, secures, and analyzes enterprise data, and Metropolis, a platform that integrates, enriches, models, and analyzes quantitative data for commercial use. Palantir's software supports activities such as anti-fraud, crisis response, cyber security, defense, disaster preparedness, disease response, healthcare delivery, intelligence, law enforcement, insurance analytics, and pharmaceutical research. Its solutions enable collaboration across and within organizations to make sense of large and complex data sets. Palantir serves government, defense, finance, healthcare, and other industries. The company was founded in 2003 and is based in Palo Alto, California.

NearPad is a software development company. They offer to help developers deliver innovations at scale while enabling users to experience developments that scale within their needs. Their platform focuses on blockchain, gaming, art, and DeFi.

Quantum-Si is focused on revolutionizing the growing field of proteomics. The company’s suite of technologies are powered by a first-of-its-kind semiconductor chip designed to enable single-molecule next-generation protein sequencing and genomics, and digitize proteomic research in order to advance drug discovery and diagnostics beyond what has been possible with DNA sequencing.

InterCure Ltd. is a medical device company that specializes in the development of innovative technologies for the treatment of cardiovascular and pulmonary diseases. Founded in 1994 and based in Hadera, Israel, InterCure has created a patented technology platform known as "Interactive Respiratory-Pacing." This platform has led to the development of product lines that offer non-drug treatments for prevalent conditions such as hypertension and heart failure. The company's flagship product, RESPeRATE, is the only FDA-cleared medical device shown to effectively reduce high blood pressure without side effects. Additionally, InterCure's heart failure treatment, InTone™, has successfully completed phase 2a clinical trials and is awaiting regulatory approval for market launch. With a strong management team and an esteemed Scientific Advisory Board, InterCure aims to lead the market in patient-focused medical devices that address significant health challenges without reliance on pharmaceuticals.

Evogene Ltd. is a computational biology company headquartered in Rehovot, Israel, focused on the discovery and development of life-science products across various industries, including agriculture, human health, and industrial applications. Utilizing its Computational Predictive Biology (CPB) platform, Evogene combines deep biological insights with big data and artificial intelligence to enhance product development efficiency and efficacy. The Agriculture segment works on seed traits and ag-chemical products aimed at improving crop performance for species such as corn, soybean, and cotton. In the Human Health sector, the company develops microbiome-based therapeutics targeting immuno-oncology and gastrointestinal disorders, along with medical cannabis products. The Industrial Applications segment concentrates on enhancing castor bean seeds for biofuel production. Evogene operates globally, with a presence in the United States, Israel, and Brazil, and maintains strategic collaborations and licensing agreements with major agricultural firms. Founded in 1999, the company leverages advanced technologies to transform life-science product development processes.