Zimmer

Paragon 28, Inc. is a medical device company specializing in products for foot and ankle surgery. Incorporated in 2010 and based in Englewood, Colorado, with an additional headquarters in Dublin, Ireland, the company offers a comprehensive range of surgical solutions, including plates, screws, allograft bone systems, and interference screws for various orthopedic procedures. Its product portfolio features advanced systems such as the PHANTOM Lapidus Intramedullary Nail for arthrodesis correction, the Proximal Rotational Metatarsal Osteotomy for bunion correction, and the Paratrooper Plantar Plate Repair System for plantar plate repairs. Paragon 28 aims to meet the diverse needs of foot and ankle surgeries through its nearly 80 product systems, addressing conditions such as hallux valgus, fracture fixation, and flat foot. The company primarily generates revenue from the United States market.

OrthoGrid specializes in developing intraoperative assessment tools aimed at enhancing orthopedic joint reconstruction and trauma procedures. The company focuses on creating anatomy-specific radiopaque grid patterns that assist orthopedic surgeons in positioning implants accurately and restoring leg length during total hip replacements, particularly via the anterior approach. OrthoGrid's portfolio includes a range of patented and patent-pending technologies designed to improve clinical outcomes by addressing critical factors such as implant positioning, limb alignment, and fracture reduction. By providing innovative tools, OrthoGrid aims to empower surgeons to make informed decisions in the operating room, ultimately enhancing patient care and alleviating joint pain.

Osteal Therapeutics is a clinical-stage specialty pharmaceutical company focused on developing innovative drug and device combination products aimed at treating musculoskeletal infections. The company’s therapeutics are designed to significantly reduce the mortality, morbidity, and healthcare costs associated with these infections. Osteal Therapeutics offers solutions for orthopedic infections and infected joint prostheses, providing fast and reliable treatment options. This enables orthopedic surgeons to deliver effective care for patients suffering from musculoskeletal diseases, ultimately improving patient outcomes and the overall management of these conditions.

OSSIS is a company focused on the development of orthopedic implants specifically designed for acetabular revisions and pelvic tumors. Utilizing advanced digital image manipulation, design software, and three-dimensional (3D) printing technology in titanium, OSSIS creates implants that provide effective anchor points for reattaching soft tissue. This innovative approach enhances the ability of medical professionals to treat their patients, improving surgical outcomes and patient care in the field of orthopedics.

Embody, Inc., established in 2014 and based in Norfolk, Virginia, is a regenerative medicine company specializing in the development and commercialization of implantable medical devices. The company focuses on addressing unmet demands in soft tissue restoration and regeneration, with a particular emphasis on tendon and ligament repair. Embody's innovative collagen-based microfiber implants are designed to replicate the biological and biomechanical properties of native tissue, aiming to restore pre-injury performance for a wide range of patients, including warfighters, athletes, and those suffering from sports injuries. The company's technology, which includes microfluidic biofabrication and electrospinning, enables it to create advanced biomaterial-based devices that enhance healthcare providers' ability to repair and regenerate damaged soft tissue.

NeuroOne Medical Technologies Corporation is a medical technology company based in Eden Prairie, Minnesota. It is dedicated to the development and commercialization of advanced thin film electrode technology designed for continuous electroencephalogram (cEEG) and stereoelectroencephalography (sEEG) recording. The company's focus extends to spinal cord stimulation, brain stimulation, and ablation solutions, targeting patients with conditions such as epilepsy, Parkinson’s disease, dystonia, essential tremors, and chronic pain resulting from failed back surgeries. NeuroOne aims to provide minimally invasive, high-definition solutions that enhance patient outcomes while potentially reducing procedural costs in the treatment of various neurological disorders.

A&E Medical Corporation is a manufacturer and designer of medical devices, specializing in a range of products used in surgical procedures. The company's offerings include temporary cardiac pacing leads, high-strength sternum closure systems, stainless steel sutures, electrosurgical instruments, surgical punches, and neurosurgical scalp clips. In addition to its core product line, A&E Medical provides contract manufacturing services, including wire and cable extrusion, electro-mechanical assembly, and sterile packaging. Headquartered in Farmingdale, New Jersey, A&E Medical serves both domestic and international markets through a comprehensive distribution network. Established in 1967, the company has built a reputation for quality and innovation in the medical device industry and operates as a subsidiary of Zimmer Biomet Holdings, Inc.

ReLign Corporation is a manufacturer and developer of advanced electrosurgical devices and accessories, specializing in arthroscopic systems for orthopedic procedures. Founded in 2011 and based in Cupertino, California, the company produces a reusable, sterilizable handle integrated with a single umbilical cable, which facilitates the cutting and removal of bone and soft tissue. This innovative design enables orthopedic surgeons to visualize, diagnose, and treat joint injuries effectively and painlessly. As of September 2020, ReLign operates as a subsidiary of Zimmer Biomet Holdings, further enhancing its capabilities in the medical device sector.

SIG Medical Corp. is a medical device manufacturer based in Hershey, Pennsylvania, established in 2016. The company specializes in developing innovative solutions for the treatment of rib fractures through a patented, minimally invasive surgical procedure. Its rib fixation system is designed to provide effective fixation, stabilization, and fusion for both normal and osteoporotic bone. This FDA-approved system aims to enhance patient care by being less costly, time-consuming, and painful compared to traditional methods. By optimizing clinical services for the operating room, SIG Medical enables surgeons to perform rib fracture repairs more efficiently, ultimately benefiting patients and reducing healthcare spending for payors.

RespondWell, LLC is a digital health company that specializes in telerehabilitation technology. Founded in 2003 and based in Grand Rapids, Michigan, the company offers a comprehensive platform designed for patients, outpatient rehabilitation clinics, hospital systems, and senior care facilities. RespondWell provides a range of modules, including prevention and rehabilitation, as well as clinical content and clinician tools, facilitating patient assessment, engagement, and reporting. The platform supports total joint replacement patients by enabling healthcare providers to connect and monitor patients while collecting valuable data. Patients can access instructional videos for physical therapy conducted by virtual instructors, enhancing their rehabilitation experience. RespondWell also features engagement incentives through in-product rewards and offers two specific online programs, Therapy@Home and Fitness@Home. The company became a subsidiary of Zimmer Biomet Signature Solutions in October 2016.

Clinical Graphics B.V., founded in 2010 and based in Delft, the Netherlands, specializes in advanced imaging technology, particularly 3D range-of-motion simulation. The company provides orthopedic surgeons and radiologists worldwide with the ability to send image data, including CT and MRI scans, to receive detailed 3D motion simulation reports. This innovative technology aids in informing treatment decisions for various hip conditions, such as dysplasia and femoroacetabular impingement, allowing physicians to better understand a patient's physiology and tailor their treatment approaches accordingly. As of September 2016, Clinical Graphics operates as a subsidiary of Zimmer Biomet Holdings, Inc.

CD Diagnostics is developing assays for orthopaedic surgeons and rheumatologists who would like greater diagnostic confidence in joint fluid analysis. Unlike current technologies, which often yield vague and ambiguous results, CygnaSure™, our lead product, offers orthopaedic surgeons and rheumatologists a rapid, accurate and reliable diagnostic answer.

Medtech’s mission statement can be summarized in the following way: Their mission consists of the broader use of medical technology for the benefit of both patient and practitioner as they strive for improved overall health and well-being. Medtech designs, develops and markets a new generation of robotic assistance for the express purpose of improved surgical techniques. Their robots contribute to safer and more stable implementation of both more effective and less invasive treatment.

Compression Therapy Concepts, Inc. specializes in the production and distribution of medical products aimed at preventing deep vein thrombosis (DVT) and reducing the risk of pulmonary embolism. Established in 1999 and based in Eatontown, New Jersey, the company offers a range of products, including the VasoPress DVT system, various garment sizes for different patient needs, and necessary connector tubing. Its offerings are designed to enhance patient outcomes and minimize complications associated with DVT by integrating with care practices in acute, long-term, and home care settings. The company operates through a sales network across the United States and emphasizes cost-effective, environmentally friendly solutions in its product line.

LDR Holding Corporation is a medical device company specializing in the development and marketing of innovative implantable spine systems and instrumentation for surgical use. Founded in 2004 and headquartered in Austin, Texas, the company offers a diverse range of spinal surgery solutions, including cervical and lumbar artificial disc systems, pedicle screw systems, cervical cages, and synthetic bone substitutes, among others. LDR Holding's products are designed to address various spine disorders and are distributed through collaborations with surgeons and distributors in multiple countries, including Australia, Japan, and the United Kingdom. The company has expanded its global presence with additional offices in France, China, Brazil, and Germany, and it was formerly known as LDR Spine USA, Inc. prior to acquiring LDR Médical. LDR Holding is committed to advancing surgical technologies that enhance patient outcomes and support the surgeon community.

Cayenne Medical, Inc. is a medical device company based in Scottsdale, Arizona, specializing in soft tissue reconstruction solutions for the knee, shoulder, and extremities. Founded in 2005, the company designs and develops a range of products for arthroscopic surgery, including the AperFix System, which facilitates anterior cruciate ligament (ACL) reconstruction using various grafts. Its offerings also include the AperFix Femoral and Tibial devices for restoring knee kinematics and anatomical reconstruction. Additionally, Cayenne Medical provides the CrossFix II System for meniscal repair, the iFix Interference Screw System for ACL procedures, and a line of shoulder products under the Quattro System for various soft tissue repairs. The company's innovative solutions aim to enhance surgical precision and improve patient outcomes in sports medicine.

Ortho Transmission has develops a skeletal implant technology.

ETEX Corporation specializes in the development, manufacturing, and commercialization of calcium phosphate-based biomaterials aimed at enhancing orthopedic clinical outcomes. As a leader in bioresorbable bone substitute materials, ETEX focuses on promoting the repair and regeneration of bone affected by trauma or disease. The company is dedicated to expanding the applications of its products by integrating them with cells, biologics, or therapeutic agents, all delivered through minimally invasive and user-friendly systems.

Biomet, Inc., together with its subsidiaries, engages in the design, manufacture, and marketing of surgical and non-surgical products primarily used by orthopedic surgeons and other musculoskeletal medical specialists in the United States, Europe, and internationally. The company’s reconstructive products include knee, hip, shoulders, and extremity joint replacement systems, as well as dental reconstructive implants, bone cements, and accessories; autologous therapy products; and the procedure-specific instrumentation required to implant the company’s reconstructive systems. It also offers various fixation devices comprising internal and external fixation devices, craniomaxillofacial fixation systems, and electrical stimulation devices. In addition, the company supplies spinal products, which include electrical stimulation devices addressing the spine, spinal fixation systems, and orthobiologics for the spine. Further, it offers sports medicine products, softgoods and bracing products, casting materials, general surgical instruments, operating room supplies, and other surgical products. The company was founded in 1977 and is headquartered in Warsaw, Indiana. Biomet, Inc. is a subsidiary of LVB Acquisition, Inc.

Normed Medizin-Technik GmbH is a subsidiary of Zimmer Biomet Holdings Inc. that focuses on the development, manufacture, and distribution of medical products globally. The company specializes in surgical solutions for hand and foot surgery, as well as pediatric orthopedics and treatments for the lower and upper extremities. Normed prioritizes quality, service, and competence in its operations, striving to meet the needs of healthcare professionals and improve patient outcomes through innovative medical technologies.

Knee Creations is an orthopedic medical device company based in New York, specializing in solutions for knee osteoarthritis. Established in 2007, it is known for pioneering the Subchondroplasty procedure, a minimally invasive technique that addresses bone defects associated with chronic bone marrow lesions by utilizing a biomimetic bone void filler. The company also develops related surgical devices and offers training for healthcare professionals to implement these innovative procedures in their practices. As of 2013, Knee Creations operates as a subsidiary of Zimmer Holdings, further enhancing its capabilities in the orthopedic field.

Dornoch Medical Systems is a U.S.-based manufacturer specializing in fluid management systems. The company offers a range of products, including an integrated infectious fluid collection and disposal system known as transposal, which is applicable in operating rooms and throughout healthcare facilities. In addition to its core offerings, Dornoch Medical Systems produces various fluid management accessories to support the safe handling and disposal of infectious fluids.

Synvasive Technology, Inc. specializes in the development, manufacturing, and distribution of advanced surgical cutting technology, focusing on reconstructive orthopedic surgery. With nearly two decades of experience, the company is recognized for its innovative instruments that enhance surgical procedures. Notably, Synvasive is the exclusive provider of STABLECUT®, a patented line of large bone surgical saw blades that has become the gold standard in the industry. Through its commitment to quality and innovation, Synvasive Technology plays a significant role in improving surgical outcomes in orthopedic practices.

ExtraOrtho, Inc. provides damage control and deformity correction solutions for surgeons, administrators, and patients. It offers XTRAFIX, an external fixation system that allows surgeons to eliminate steps, bars, and clamps. ExtraOrtho, Inc. was formerly known as QFx Technologies, Inc. and changed its name to ExtraOrtho, Inc. in May 2009. The company was founded in 2007 and is based in Memphis, Tennessee. As of November 10, 2011, ExtraOrtho, Inc. operates as a subsidiary of Zimmer Holdings, Inc.

Zfx provides dentists, dental labs and milling centres with high-end applications from the entire dental process chain: from the intraoral and desktop scanner and dental shade measuring instrument through to digital axiography and CAD software to the complete solution for dental milling providers. In addition, as Zfx partner you benefit from the new and unique Zfx online platform, which allows for continues control and replacement opportunities during the entire dental production process.

Sodem Diffusion S.A., the manufacturer of SoPlus Orthopaedic Surgical Power Tools based in Geneva, Switzerland. The company will be re-named Zimmer Surgical, S.A. and will be part of Zimmer Surgical, headquartered in Dover, Ohio.

Beijing Montagne Medical Device Co., Ltd. is a privately held company deals and engages in the development, production, and sale of artificial joints in China and abroad.

Abbott Spine, founded in 1996 and based in Austin, Texas, with an international facility in Bordeaux, France, specializes in developing innovative technologies for the treatment of spine diseases. The company focuses on creating less invasive spinal implant solutions that enable surgeons to effectively address various spinal disorders, diseases, and injuries. Key products include the InCompass Pedicle Screw System, the Pathfinder Minimally Invasive Pedicle Screw System, the Wallis Interspinous Stabilizer System (available outside the U.S.), the Ant-Cer Dynamic Cervical Plate, and the Universal Clamp. Through its advancements, Abbott Spine aims to improve surgical outcomes and enhance patient recovery in the field of spinal care.

Endius, founded in 1997, focuses on creating innovative solutions for spine surgery, aiming to provide less traumatic and more effective options for patients suffering from back pain. The company specializes in the development of invasive and endoscopic spine surgery products and implants. Among its notable offerings are the Atavi system, designed for atraumatic lumbar spine fusion procedures, the TiTLE system, and the MDS microdebrider system. Endius is dedicated to advancing total spine surgery solutions, enhancing surgical outcomes and patient recovery. The company was acquired by Zimmer Biomet Holdings, further integrating its technologies into the broader medical device landscape.

Biomet designs, manufactures and markets surgical and non-surgical products used primarily by orthopedic surgeons.

Implex is a company focused on developing innovative solutions in the fields of information technology and orthopedic implants. It offers a range of IT services, including website design, internet and server networks, online broadcasting, and managed services. In the orthopedic sector, Implex specializes in creating advanced implant products, such as hedrocel biomaterial, designed to mimic the structure of human cancellous bone. This technology aims to enhance the treatment options available to orthopedic surgeons for addressing diseases and injuries related to the musculoskeletal system. Through its dual focus on IT services and orthopedic innovations, Implex seeks to significantly impact both fields.

Centerpulse is a privately held medical technology group, serves the reconstructive orthopedic device, spinal device, and dental implant markets on a global basis.