Founded in 2000, General Catalyst is a venture capital firm specializing in early-stage and growth equity investments. It focuses on accelerating ideas, careers, and companies towards success by providing ongoing momentum and mentorship based on deep experience.

Alumni Ventures Group is a venture capital firm based in Manchester, New Hampshire, with offices across North America. It provides access to venture investing for individual accredited investors, particularly alumni networks, by offering diversified portfolios of venture opportunities and allowing members to invest alongside fellow alumni in ventures led by peers. The firm backs early-stage and later-stage opportunities across technology, consumer, healthcare, financial services, and other sectors, with a sector- and geography-agnostic approach. It typically invests between $10,000 and $3 million per deal and emphasizes the involvement of alumni connections and an institutional lead investor in opportunities. Alumni Ventures also offers focused funds to broaden participation, enabling accredited investors to access venture portfolios diversified by type, sector, stage, and geography. The model aims to democratize access to venture capital while maintaining rigorous selection standards through alumni networks.

Founded in 1995, SOSV is a global venture capital firm headquartered in New Jersey. It focuses on seed-to-growth stage investments in deep tech innovations, primarily in bio-tech/life sciences and hardware/robotics sectors, with a commitment to human and planetary health.

Founded in 1989, OrbiMed is a New York-based healthcare-dedicated investment firm managing approximately $5 billion in assets. It invests across the spectrum of healthcare companies, from private start-ups to large multinational corporations, focusing on biopharmaceuticals, life sciences, digital health, medical devices, and diagnostics sectors globally.

Right Side Capital Management is a San Francisco-based venture capital firm that focuses on early-stage, pre-seed technology startups in underserved segments of the ecosystem. It invests in a high-volume, capital-efficient portfolio, typically funding rounds of 50,000 to 500,000 and making roughly 75 to 100 investments per year. The firm targets opportunities across the United States and internationally, including Canada, Israel, Australia, New Zealand, and Western Europe, prioritizing companies with scalable products and prudent capital use outside major metro hubs. Since its inception, it has built a broad portfolio across many states. It commits to a fast decision process, often delivering a yes or no within two weeks to help founders establish momentum.

Khosla Ventures is a California-based venture capital firm founded in 2004 by Vinod Khosla. It provides capital and strategic guidance to startups across stages, focusing on technology-driven companies in areas such as artificial intelligence, climate and sustainability, enterprise software and services, fintech, digital health, medical technology and diagnostics, therapeutics, consumer products, and frontier technologies. The firm backs bold ventures with the potential to disrupt markets and improve lives, supporting companies from early to growth stages and working closely with entrepreneurs to apply science, technology and innovative business models. While primarily investing in North American technology companies, Khosla Ventures pursues opportunities globally and emphasizes experimentation and impact alongside financial returns. The firm also maintains related impact initiatives that support entrepreneurs addressing socio-economic challenges in emerging markets.

Founded in Singapore in 2017, Antler is an early-stage venture capital firm that invests globally. It focuses on backing exceptional founders from day one, offering a global community network of co-founders, talent, advisors, expansion support, and capital across various sectors such as technology, healthcare, finance, consumer goods, and more.

New Enterprise Associates is a venture capital firm founded in 1977 and based in Menlo Park, California, with offices in the United States, India and China. It makes investments across technology and healthcare startups at multiple stages, from seed to growth, including software, cloud, data, internet services, fintech, AI, e-commerce, and enterprise technology, as well as healthcare information technology, life sciences, medical devices, and biopharma. It also considers energy technology and infrastructure opportunities, such as solar, batteries and smart grids. The firm pursues a global approach, with activity in the United States, Asia and other regions, and supports companies through rounds of financing ranging from small to sizable investments as they scale. NEA focuses on building portfolios in software, IT services, consumer technology, and healthcare technology, backing ambitious entrepreneurs across sectors and geographies.

Founded in Boston in 2004, RA Capital is an investment firm specializing in life sciences and drug development. Its team, with backgrounds in biology, chemistry, medicine, and industry experience, invests in early-stage companies with promising technologies and products across healthcare and life science sectors.

Andreessen Horowitz is a venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz and based in Menlo Park, California. It funds startups across the entire lifecycle, from seed to growth, with a broad focus on software and technology-enabled businesses. The firm backs companies in software, cloud infrastructure, digital platforms, data storage, and mobile and Internet services, as well as sectors at the intersection of technology with life sciences, such as bio healthcare and computational medicine. Its investments span artificial intelligence, fintech, consumer and enterprise software, crypto and blockchain, cybersecurity, and related infrastructure. Through strategic guidance and a hands-on approach, the firm aims to help portfolio companies scale and innovate.

Founded in 2009 and based in New York City, BoxGroup is an early-stage investment fund focusing on pre-seed to Series A rounds. It invests globally, with a primary focus on New York City, Silicon Valley, and Los Angeles. The firm typically allocates between $50,000 and $250,000 per investment across various sectors including consumer, enterprise, fintech, healthcare, life science, marketplace, synthetic biology, and climate.

Founded in 2011, StartUp Health is dedicated to improving global health through collaboration with entrepreneurs. It invests in 'Health Transformers' across six continents, focusing on various health moonshots such as Access to Care, Cure Disease, and Mental Health. With over 330 companies in its portfolio, it's backed by prominent investors.

Eli Lilly and Company is a global pharmaceutical leader engaged in the discovery, development, manufacture, and sale of medicines. It operates facilities in the United States, Puerto Rico, and many other countries, with products sold in about 135 countries. The company focuses on therapies in neuroscience, cardiometabolic, cancer, and immunology, and also conducts research in animal health and animal agriculture. Lilly supports patient outcomes and education through a philanthropic foundation that funds programs in underserved communities, including STEM education in Indianapolis.

Qiming Venture Partners is a China-based venture capital firm founded in 2006, with offices in Shanghai, Beijing, Suzhou, Hong Kong and Singapore, and a global arm through Qiming Venture Partners USA. It manages multiple funds and invests in early and growth-stage companies across technology, information technology, healthcare, new consumer sectors, AI, robotics, semiconductors, software and digital health. The firm emphasizes a hands-on approach, often taking board seats and providing operational guidance to help CEOs scale and reach exits. Through its investments, it has backed hundreds of companies and supported numerous IPOs and M&A outcomes, with unicorns among its portfolio, illustrating breadth and depth across China and international markets.

Founded in 1993, Maverick Capital is a global investment firm with offices across New York, San Francisco, London, Hong Kong, Philadelphia, and Dallas. The firm primarily manages private investment funds for qualified investors, focusing on long/short hedged equity strategies to grow and preserve capital. Since its inception, Maverick has strategically invested in private companies with disruptive business models or technologies, actively partnering with portfolio teams to build businesses.

Polaris Partners is a venture capital firm based in Boston, Massachusetts, with offices in San Francisco. Founded in 1996, it targets investments in technology and life science companies across the United States and Europe, supporting startups from early formation to profitable growth. The firm's healthcare and biotechnology focus encompasses digital health, consumer-centric care delivery, patient-provider solutions, data science and analytics, as well as therapeutics, genomics and other life science platforms. It backs companies across business-to-business and business-to-consumer models, software as a service, healthcare information technology and health tech sectors, partnering with repeat entrepreneurs to build durable, scale-ready businesses.

Founded in 2014, Gaingels is a venture investment syndicate dedicated to supporting the LGBT+ community. It invests globally in companies led by LGBT+ founders or C-suite executives at all stages of growth, focusing on inclusivity and positive social change.

Casdin Capital is a New York‑based investment firm founded in 2012 by Eli Casdin. The firm specializes in fundamental research and long‑short equity strategies focused on the life sciences and healthcare sectors, including oncology, digital health, and agtech. In addition to its public‑market fund, Casdin Capital invests in early‑stage to late‑stage private companies within these industries. It operates as a Registered Investment Adviser and, as of October 2020, managed approximately $2.2 billion in assets.

Everywhere Ventures is a New York-based venture capital firm focused on early-stage, pre-seed investments. Founded by founders for founders, it operates as a community-powered investing platform that unites capital, expertise, and mentoring from a broad network of founders and operators across ten micro funds. The firm supports global startups in their first financing rounds, with a focus on purpose-driven teams across money, health, and work verticals. Its model combines hands-on guidance from experienced builders with early-stage funding to help entrepreneurs build durable companies.

Founded in 2015, Flare Capital Partners is a Boston-based venture capital firm specializing in early-stage investments in healthcare technology. The firm focuses on transformational technologies and services that enable value-based healthcare, with an interest in medical devices, biopharmaceuticals, diagnostics, predictive medicine, data-centric devices, healthcare software, services, and digital health.

Frist Cressey Ventures is a venture capital firm headquartered in Nashville, Tennessee, focused on early- and growth-stage investments in healthcare and digital health technologies and services. It seeks opportunities that improve quality of care, system integration, patient outcomes, and population health, partnering with entrepreneurs to accelerate growth and translate viable solutions into practical healthcare improvements. The firm targets technology-enabled healthcare enterprises and service businesses with strong potential to advance care delivery and health outcomes, and it emphasizes value-added collaboration with portfolio companies.

Founded in 2018, Town Hall Ventures is a New York-based investment firm dedicated to transforming the U.S. healthcare market through technology. It invests in and supports visionary entrepreneurs focused on improving care delivery and health outcomes for underserved populations.

Established in 2020, the European Innovation Council supports innovative startups and researchers with promising ideas, focusing on early-stage companies with positive environmental, social, or governance impacts. It co-invests alongside private investors.

Founded in 2015, Liquid 2 Ventures is a venture capital firm based in San Francisco, California. It specializes in seed-stage investments for technology startups.

Founded in 1969, F-Prime Capital is a venture capital firm based in Cambridge, Massachusetts. It invests globally in technology and healthcare sectors, supporting entrepreneurs with its extensive domain expertise and relationships.

First Round Capital is a San Francisco-based venture capital firm that concentrates on seed- and early-stage investments, often supporting pre-revenue startups across sectors including enterprise software, fintech, healthcare, consumer, hardware, artificial intelligence, and web3. The firm emphasizes a community-driven approach, providing founder-focused services, mentorship, and access to a broad founder network to help companies grow. It operates nationally with offices in San Francisco and New York and seeks to take an active role in portfolio companies to aid scaling and access to follow-on funding.

Oak HC/FT is a venture and growth equity investment firm specializing in healthcare information services and financial technology. It supports portfolio companies with strategic counsel, board-level participation, and access to a broad network of industry leaders to drive transformation in these sectors. The firm, based in Stamford, Connecticut, operates within the Oak Investment Partners family, leveraging sector-specific expertise from Oak's healthcare and fintech teams to build and scale innovative businesses.

Founded in 1999, Versant Ventures is a global healthcare investment firm dedicated to supporting exceptional entrepreneurs building innovative companies. With over $2 billion under management and offices across North America and Europe, the firm invests across all stages of healthcare company development, with a focus on novel therapeutics. Versant's team, with deep investment, operating, and scientific expertise, takes a hands-on approach to company building.

City Light Capital is a New York-based venture capital firm founded in 2004 that invests in seed, early, and growth-stage companies across technology, education, digital health, climate, food, wellness, energy, agriculture, safety and care, and the environment in the United States. It emphasizes impact investing, partnering with experienced teams to build category-defining solutions in education, safety and care, and the environment, aiming to scale revenue in ways that improve lives. Notable portfolio companies include 2U, ShotSpotter, Trilogy Education, and Ready Responders.

Venrock is a Palo Alto-based venture capital firm founded in 1969 as the venture capital arm of the Rockefeller family. It concentrates on seed and early-stage investments in technology and healthcare, with interests spanning information technology, life sciences and related sectors in the United States. The firm has supported a broad portfolio of companies, including Apple, Intel, Illumina, DoubleClick, Athenahealth, Gilead Sciences, Nest, SlideShare and Tudou. Venrock emphasizes long-term partnerships with entrepreneurs, combining hands-on venture support with rigorous data analysis to help startups grow into enduring companies.

Echo Health Ventures is a venture capital firm that invests in healthcare companies, health technology, insurance technology and digital health in the United States. Based in Seattle with offices in Durham and Portland, the firm is stage-agnostic and aims to accelerate healthcare innovations to scale nationally by offering strategic guidance in addition to capital. Echo Health Ventures focuses on building deep, high-value relationships with portfolio companies to support growth and clinical impact, partnering with startups to advance patient care, improve care delivery, and broaden access to digital health tools.

8VC is a technology and life sciences investment firm that partners with founders to develop transformational technologies and create long-term value. Its activities span sectors such as healthcare, logistics, software, energy, manufacturing, enterprise IT, and life sciences, with a focus on supporting early-stage and growth opportunities in the United States and beyond.

High-Tech Gründerfonds Management GmbH is a venture capital firm based in Bonn, Germany, specializing in early-stage investments in high-tech startups. Established in 2005, the firm focuses on technology-driven companies across various sectors, including information and communication technology, life sciences, healthcare, automation, and cleantech. HTGF typically invests in companies that have been operational for no more than one year, aiming to contribute up to €0.6 million in initial funding and up to €3 million in follow-on financing. The firm seeks a minority stake, generally around 15%, and provides a subordinated loan convertible into equity, with deferred interest for up to four years to support liquidity. With a total investment volume of approximately €895.5 million across three funds, HTGF has successfully supported over 500 startups and attracted more than €2 billion in follow-on investments from external sources. The firm's investors include notable public and private entities, underscoring its role as a key player in fostering innovation and growth within the German startup ecosystem.

Novo Holdings is a Danish holding and investment firm managing the assets of the Novo Nordisk Foundation. Established in 1999, it invests globally in life science companies at all stages of development, with a portfolio also including equities, bonds, real estate, and infrastructure.

Deerfield Management is a New York-based investment firm established in 1994 that focuses on healthcare. It operates across investment, information, and philanthropy to support the healthcare ecosystem. The firm provides private and public investments and offers long-term, structured capital to both public and private healthcare companies. Its portfolio spans life sciences, medical devices, diagnostics, digital health, and health services. As an investment adviser, it seeks opportunities in healthcare products and services and aims to accelerate innovation by combining capital with industry insight.

Founded in 2015, FJ Labs is a New York-based venture capital firm focusing on stage-agnostic investments in marketplaces and consumer-facing startups. Their investment range varies from $50,000 to $5,000,000, typically at seed or series A stages.

Invus Financial Advisors, LLC is an employee-owned investment firm based in New York, founded in 2006. The firm specializes in private equity investments and manages pooled investment vehicles, including hedge funds and funds of funds. Invus focuses on making direct and indirect investments in special situations, venture capital, and growth equity stages, with an emphasis on smaller companies and opportunistic co-investments. The firm adopts a flexible approach, recognizing the uniqueness of each company and the complexities of business transformation. Invus maintains a long-term commitment to its investments, aligning its incentives with those of its partners. With a history of empowering owner-managers since 1985 and a strong backing from a group of European families, Invus Financial Advisors manages over $4 billion in an evergreen fund and operates additional offices in London, Paris, and Hong Kong.

Founded in 1986, ARCH Venture Partners is a venture capital firm specializing in investments that bring innovations in life sciences to market. It focuses on companies co-founded by scientists and entrepreneurs, with a strong track record in commercializing technologies from academic research institutions and national laboratories.

Founded in 2014, Goodwater Capital is a venture capital firm based in Burlingame, California. It invests in early-stage consumer technology companies, empowering exceptional entrepreneurs to solve pressing problems and create global impact.

Alexandria Venture Investments is the strategic venture capital arm of Alexandria Real Estate Equities. Based in Pasadena, California, it provides long-term strategic capital to innovative life sciences and technology companies developing breakthrough therapies, diagnostics, and platforms across biopharma, digital health, agrifoodtech, agtech, and related healthcare fields. Established in 1996, the firm invests across seed, early, and growth stages and leverages its deep industry knowledge, extensive investor networks, and scientific advisory resources to support portfolio companies. The unit also pursues opportunities at the intersection of real estate, life sciences, and technology, reflecting its parent company's sector focus and integrated ecosystem approach. It aims to help entities advance human health by partnering with founders to scale transformative technologies.

Pioneer Fund is a San Francisco-based venture capital firm founded in 2017 that makes early-stage investments across a wide range of sectors, including consumer products and services, financial services, information technology, advanced manufacturing, blockchain, life sciences, gaming, artificial intelligence and machine learning, construction technology, education technology, fintech, agriculture technology, advertising technology, augmented reality, autonomous vehicles, legal technology, oncology, pet technology, real estate technology, ride-hailing, SaaS and supply chain technology. The firm benefits from a network of more than 420 Y Combinator alumni, enabling it to identify and support YC-backed startups.

IP Group is a London-based corporate firm that provides financial, strategic, and commercial expertise to clients internationally. Founded in 2001, the company focuses on creating value through the commercialisation of intellectual property derived from research-intensive institutions. It manages the end-to-end process of identifying viable IP, developing or partnering to build value, and establishing commercial arrangements that translate scientific advances into practical products and businesses. IP Group combines industry insight and financial experience to support science- and technology-based ventures, offering capital as well as strategic guidance to help companies grow and accelerate the impact of research. Its work spans clean technology, life sciences, and other deep technology sectors, with a track record of backing and developing ventures that aim to deliver tangible societal and economic outcomes.

Established in 2005, SMBC Venture Capital is a Tokyo-based corporate venture capital arm of Sumitomo Mitsui Banking Corporation. It invests primarily in early-stage companies operating within the information technology, life sciences, services, and manufacturing sectors.

Founded in 2009, Thrive Capital is a venture capital firm based in New York. It focuses on investing in and building internet, software, and technology-enabled companies.

Bossa Invest is a venture capital firm based in Sao Paulo, Brazil, founded in 2011, that manages investment portfolios and provides asset management services to clients across sectors, with a focus on software as a service companies, and analyzes market trends to inform its investment decisions while operating in finance, technology, and real estate.

Boston-based venture capital firm founded in 2005 that focuses on early-stage and select growth investments in information technology and related services. The firm backs enterprise IT companies, emphasizing information security, cloud infrastructure, data analytics, and software-as-a-service models, as well as technology-enabled business services and digital health, and it also targets healthcare IT, fintech, mobile software, and next-generation software. It prefers open source and SaaS delivery. Typically investing initial rounds of 2 to 5 million and totaling 6 to 10 million per company, it seeks board representation and often serves as lead or first institutional investor, with minority to majority stakes ranging from 20 to 80 percent. The firm reserves capital for opportunistic investments in more mature companies where its team has prior experience and focuses on opportunities in the Northeast United States.

Advantage Capital Partners is a United States‑based venture capital firm that provides growth equity, debt, and mezzanine financing to small and mid‑market companies, with a focus on underserved communities and state and local economic development. The firm invests across sectors including manufacturing, technology, business services, life sciences, and energy, and also supports real estate development projects with equity and debt. It typically makes initial investments ranging roughly from half a million to ten million in companies with modest sales, and may participate in larger follow‑on rounds or co‑invest with other firms. It uses senior debt, mezzanine debt, subordinated loans, and government‑guaranteed lending, and often pursues equity positions through preferred shares or convertible notes. Advantage Capital operates nationwide in the United States, with roots in New Orleans and offices in multiple states, and has backed thousands of jobs and housing projects as part of its mission to expand inclusive economic growth.

Founded in Boston, Massachusetts in 2016, Transformation Capital is a growth-focused investment firm specializing in the healthcare sector across the United States. Originally established as Leerink Transformation Partners LLC, it spun off from SVB Financial Group to operate independently under the leadership of Todd Cozzens and Jared Kesselheim, MD.

Founded in 2000, Lux Capital is a venture capital firm based in New York and Silicon Valley. It manages over $5 billion in assets, focusing on seed to growth investments at the intersection of technology and sciences. Lux actively supports entrepreneurs building successful businesses in high-growth sectors such as biochemistry, material science, electronics, infrastructure, aerospace, genomics, synthetic biology, and robotics.

Omega Funds is a Boston-based venture capital and private equity firm founded in 2004 that concentrates on early-stage investments in healthcare and biotech across North America and Western Europe, backing companies in life sciences, digital health, immunology, rare diseases, precision medicine, oncology, cybersecurity, and software-as-a-service.