ZeroTo510 is a unique, entrepreneurial accelerator program that focuses on leveraging a key regional strength of the Memphis area: medical device research and manufacturing. The goal of ZeroTo510 is to help medical device startups to navigate the startup process, refine their business models and achieve the Food and Drug Administration's 510(k) premarket notification filing. This goal is accomplished through an intensive, mentorship-driven, 90-day program of instruction and hands-on activities geared at guiding the entrepreneur through the process. In addition, each company chosen for the program will receive an investment of up to $150,000 in seed funding to help jump-start their finances.
EndoShunt Medical, founded in 2022 and based in Nashville, Tennessee, specializes in developing a medical device aimed at targeted hemorrhage control in emergency situations. The company's innovative device facilitates endovascular shunting of blood past hemorrhaging vessels, allowing surgeons to perform definitive repairs while maintaining blood flow. This technology is designed to enhance outcomes in critical care scenarios, addressing the urgent need for effective solutions in managing severe bleeding.
Winter Innovations
Seed Round in 2019
Winter Innovations is a medical device company based in Knoxville, TN, focused on enhancing patient outcomes following orthopedic injuries. Founded in 2018, the company is currently developing EasyWhip, a patent-pending suturing needle specifically designed for orthopedic ligament and tendon reconstruction surgeries. This innovative device aims to simplify and standardize the whip stitching process, providing surgeons with improved ease of use, speed, stability, and versatility. By streamlining these procedures, Winter Innovations seeks to enhance the efficiency and consistency of orthopedic reconstruction, ultimately benefiting both surgeons and patients.
Path Ex
Venture Round in 2017
Path Ex, Inc. is a Nashville-based company established in 2017 that specializes in the development of extracorporeal blood-cleansing equipment aimed at treating sepsis, a severe and often fatal condition linked to blood-borne infections. The company has created a proprietary technology that selectively separates and captures bacteria and toxins from human blood, offering a novel approach to treatment. Unlike traditional methods that rely on broad-spectrum antibiotics to kill infections, Path Ex's device effectively removes intact bacteria from the bloodstream, regardless of the bacteria type or antibiotic resistance. This innovative technology has the potential to improve patient outcomes by reducing diagnostic times, treatment costs, readmission rates, and fatalities associated with sepsis.
SOMAVAC Medical Solutions
Seed Round in 2016
SOMAVAC Medical Solutions, Inc. is a medical technology company based in Memphis, Tennessee, that specializes in enhancing post-operative care. Founded in 2016, the company develops innovative solutions to address complications arising from surgeries, particularly those related to breast cancer, such as mastectomies and abdominoplasties. Its flagship product, the SOMAVAC 100, is a sustained vacuum system designed to improve the recovery experience by effectively removing excess fluids and mitigating the risk of seroma formation. By employing negative pressure therapy, SOMAVAC aims to hold tissue layers together during the healing process, thereby facilitating better outcomes for patients following various surgical procedures.
Cast21
Seed Round in 2016
Cast21 is a medical product developer based in Memphis, Tennessee, focused on creating innovative orthopedic solutions for fracture and joint care. Established in 2015, the company has developed a waterproof and breathable cast designed to enhance patient comfort and facilitate recovery. Its unique design not only allows for skin hygiene—enabling patients to wash and scratch beneath the cast—but also supports the integration of electronic therapies aimed at reducing healing time. By prioritizing user experience and effective treatment, Cast21 seeks to improve the overall recovery process for individuals with orthopedic injuries.
SweetBio
Pre Seed Round in 2015
SweetBio, Inc. is a medical device company based in Memphis, Tennessee, specializing in the research, development, and manufacturing of innovative wound care solutions. Founded in 2015, the company focuses on bioengineering membranes that utilize medical-grade Manuka honey to enhance healing and combat infections associated with wounds, pressure ulcers, diabetic ulcers, surgical wounds, and abrasions. SweetBio's unique honey-incorporated absorbable membranes are designed to improve the efficacy of wound care treatments, offering healthcare professionals a new platform for addressing both chronic and acute wounds effectively.
Blood Monitoring Solutions
Seed Round in 2014
Blood Monitoring Solutions, Inc. is dedicated to developing innovative blood monitoring systems aimed at reducing blood wastage. Based in Memphis, Tennessee, the company has created a smart blood transport system that enables blood banks to continuously monitor the temperature and integrity of each blood unit. This proactive, data-driven approach not only enhances patient safety but also helps hospitals minimize costs associated with blood spoilage. By ensuring that blood is stored within the appropriate temperature range, the company's solutions allow for longer preservation of blood supplies, ultimately supporting more effective transfusion practices in healthcare settings.
Better Walk
Seed Round in 2013
Better Walk Inc. is an innovative company that specializes in the design and development of crutches. Established in 2013 and headquartered in Atlanta, Georgia, the company aims to improve traditional crutch technology by alleviating pressure from the underarm area and minimizing direct force on the wrist of users. Better Walk's commitment to innovation is a fundamental aspect of its culture, which was further strengthened during its participation in the Zero To 510 accelerator in Memphis, where it secured early venture funding. In late 2014, the company shifted its focus to finalizing the Better Walk crutch, positioning itself for production and an anticipated product launch in early 2015.
Restore Medical Solutions
Series A in 2012
Restore Medical Solutions is a medical device company focusing on products and techniques that promote SSI reduction, safety, and productivity within healthcare. The company manufactures a sterilization tray system that reduces the risk of infection from contaminated medical instruments. Its modular sterilization tray systems reduce the potential risk of infection from contaminated instruments and enable surgical departments to improve the quality of care while reducing cost. Founded in 2012, Restore Medical Solutions is headquartered in Memphis, Tennessee.
Urova Medical
Seed Round in 2012
Urova Medical Inc. is a urological device company based in Memphis, Tennessee, focused on creating innovative solutions for stress urinary incontinence in women. Founded in 2012, the company developed its technology through a collaborative effort by biomedical engineering students at Johns Hopkins University, guided by expert physicians from the institution's renowned urological center. Urova Medical collaborates with urologists, gynecologists, and clinical researchers to create effective and convenient treatments for this condition. The company has also participated in the Zeroto510 Accelerator program, which is supported by local venture capital firms, further enhancing its development and outreach efforts.
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